Yoshiaki Murakami

Last Updated :2020/10/08

Affiliations, Positions
Hiroshima University Hospital(Medical), Contributing Professor
E-mail
mura777hiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Doctor of Philosophy in Medical Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Digestive surgery

Research Keywords

  • pancreatic cancer
  • biliary cancer
  • chronic pancreatitis
  • acute pancreatitis
  • chemotherapy
  • surgery

Affiliated Academic Societies

  • Japanese Society for Abdominal Emergency Medicine

Educational Activity

Course in Charge

  1. 2020, Undergraduate Education, Intensive, Practice for medical research

Research Activities

Academic Papers

  1. Remnant pancreatic parenchymal volume predicts postoperative pancreatic exocrine insufficiency after pancreatectomy, SURGERY, 159(3), 885-892, 201603
  2. Nerve Growth Factor Expression Is Not Associated with Perineural Invasion in Extrahepatic Cholangiocarcinoma, DIGESTIVE DISEASES AND SCIENCES, 61(3), 774-784, 201603
  3. Preoperative Biliary Drainage in Cases of Borderline Resectable Pancreatic Cancer Treated with Neoadjuvant Chemotherapy and Surgery, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2016
  4. Prognosis after surgical treatment for pancreatic cancer in patients aged 80years or older: a multicenter study, JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 23(3), 188-197, 201603
  5. Evaluation of the efficacy of daikenchuto (TJ-100) for the prevention of paralytic ileus after pancreaticoduodenectomy: A multicenter, double-blind, randomized, placebo-controlled trial, SURGERY, 159(5), 1333-1341, 201605
  6. Survival effects of adjuvant gemcitabine plus S-1 chemotherapy on pancreatic carcinoma stratified by preoperative resectability status, JOURNAL OF SURGICAL ONCOLOGY, 113(4), 405-412, 20160315
  7. Prognostic Impact of Para-Aortic Lymph Node Micrometastasis in Pancreatic Ductal Adenocarcinoma, ANNALS OF SURGICAL ONCOLOGY, 23(6), 2019-2027, 201606
  8. Preoperative Coil Embolization in Patients With a Replaced Hepatic Artery Scheduled for Pancreatectomy With Splanchnic Artery Resection Helps to Prevent lschemic Organ Injury, JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 40(1), 172-176, 2016
  9. Prognostic value of circulating tumour DNA in patients undergoing curative resection for pancreatic cancer, BRITISH JOURNAL OF CANCER, 115(1), 59-65, 20160628
  10. Grade B pancreatic fistulas do not affect survival after pancreatectomy for pancreatic cancer: A multicenter observational study, SURGERY, 160(2), 293-305, 201608
  11. Reappraisal of Total Pancreatectomy in 45 Patients With Pancreatic Ductal Adenocarcinoma in the Modern Era Using Matched-Pairs Analysis Multicenter Study Group of Pancreatobiliary Surgery in Japan, PANCREAS, 45(7), 1003-1009, 201608
  12. Does Preoperative Biliary Drainage Compromise the Long-Term Survival of Patients With Pancreatic Head Carcinoma?, JOURNAL OF SURGICAL ONCOLOGY, 111(3), 270-276, 20150301
  13. Is Pancreatic Fistula Associated with Worse Overall Survival in Patients with Pancreatic Carcinoma?, WORLD JOURNAL OF SURGERY, 39(2), 500-508, 201502
  14. Identification of Risk Factors for Pancreatic Exocrine Insufficiency After Pancreaticoduodenectomy Using a C-13-Labeled Mixed Triglyceride Breath Test, WORLD JOURNAL OF SURGERY, 39(2), 516-525, 201502
  15. Reappraisal of Peritoneal Washing Cytology in 984 Patients with Pancreatic Ductal Adenocarcinoma Who Underwent Margin-Negative Resection, JOURNAL OF GASTROINTESTINAL SURGERY, 19(1), 6-14, 201501
  16. Portal or superior mesenteric vein resection in pancreatoduodenectomy for pancreatic head carcinoma, BRITISH JOURNAL OF SURGERY, 102(7), 837-846, 201506
  17. Postoperative prognosis of pancreatic cancer with para-aortic lymph node metastasis: a multicenter study on 822 patients, JOURNAL OF GASTROENTEROLOGY, 50(6), 694-702, 201506
  18. National Comprehensive Cancer Network Resectability Status for Pancreatic Carcinoma Predicts Overall Survival, WORLD JOURNAL OF SURGERY, 39(9), 2306-2314, 201509
  19. Postpancreatoduodenectomy Hemorrhage Treated by Combined Transcatheter Arterial Embolization and Superior Mesenteric Artery to Iliac Artery Bypass: Report of a Case, INTERNATIONAL SURGERY, 100(6), 1084-1088, 201506
  20. An Increased Number of Perineural Invasions Is Independently Associated With Poor Survival of Patients With Resectable Pancreatic Ductal Adenocarcinoma, PANCREAS, 44(8), 1345-1351, 201511
  21. Arteriography after embolization before distal pancreatectomy with en bloc celiac axis resection, MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES, 24(6), 350-355, 20151102
  22. Proposed preoperative risk factors for early recurrence in patients with resectable pancreatic ductal adenocarcinoma after surgical resection: A multi-center retrospective study, PANCREATOLOGY, 15(6), 674-680, 2015
  23. Impact of Preoperative Biliary Drainage on Long-Term Survival in Resected Pancreatic Ductal Adenocarcinoma: A Multicenter Observational Study, ANNALS OF SURGICAL ONCOLOGY, 22, S1238-S1246, 201512
  24. Clinical pharmacokinetics of meropenem in pancreatic juice and site-specific pharmacodynamic target attainment against Gram-negative bacteria: Dosing considerations, PANCREATOLOGY, 14(2), 95-99, 2014
  25. Indicators for proper management of surgical drains following pancreaticoduodenectomy., Journal of Surgical Oncology, 109(7), 702-707, 20140101
  26. Influence of preoperative anti-cancer therapy on resectability and perioperative outcomes in patients with pancreatic cancer: Project study by the Japanese Society of Hepato-Biliary-Pancreatic Surgery, JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 21(2), 148-158, 201402
  27. Short- and long-term results of lateral pancreaticojejunostomy for chronic pancreatitis: a retrospective Japanese single-center study, JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 21(6), 426-432, 201406
  28. Indicators for proper management of surgical drains following pancreaticoduodenectomy, JOURNAL OF SURGICAL ONCOLOGY, 109(7), 702-707, 201406
  29. Elevated perioperative serum CA 19-9 levels are independent predictors of poor survival in patients with resectable cholangiocarcinoma, JOURNAL OF SURGICAL ONCOLOGY, 110(4), 422-429, 20140915
  30. Pharmacokinetics and pharmacodynamic target attainment of intravenous pazufloxacin in the bile of patients undergoing biliary pancreatic surgery, JOURNAL OF CHEMOTHERAPY, 26(5), 287-292, 201410
  31. Perioperative Antibiotics Covering Bile Contamination Prevent Abdominal Infectious Complications After Pancreatoduodenectomy in Patients With Preoperative Biliary Drainage, WORLD JOURNAL OF SURGERY, 38(11), 2952-2959, 201411
  32. Concurrent analysis of human equilibrative nucleoside transporter 1 and ribonucleotide reductase subunit 1 expression increases predictive value for prognosis in cholangiocarcinoma patients treated with adjuvant gemcitabine-based chemotherapy, BRITISH JOURNAL OF CANCER, 111(7), 1275-1284, 20140923
  33. Nonalcoholic Fatty Liver Disease After Pancreatoduodenectomy is Closely Associated With Postoperative Pancreatic Exocrine Insufficiency, JOURNAL OF SURGICAL ONCOLOGY, 110(6), 720-726, 201411
  34. Antibiotic prophylaxis for endoscopic retrograde chlangiopancreatography increases the detection rate of drug-resistant bacteria in bile, JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 21(9), 712-718, 201409
  35. Benefit of portal or superior mesenteric vein resection with adjuvant chemotherapy for patients with pancreatic head carcinoma, JOURNAL OF SURGICAL ONCOLOGY, 107(4), 414-421, 201303
  36. Penetration of meropenem into human pancreatic juice, SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 45(5), 404-406, 201305
  37. Early initiation of adjuvant chemotherapy improves survival of patients with pancreatic carcinoma after surgical resection, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 71(2), 419-429, 201302
  38. Combined analysis of intratumoral human equilibrative nucleoside transporter 1 (hENT1) and ribonucleotide reductase regulatory subunit M1 (RRM1) expression is a powerful predictor of survival in patients with pancreatic carcinoma treated with adjuvant gemcitabine-based chemotherapy after operative resection, SURGERY, 153(4), 565-575, 201304
  39. Effect of Daikenchuto (TJ-100) on Postoperative Bowel Motility and on Prevention of Paralytic Ileus after Pancreaticoduodenectomy: A Multicenter, Randomized, Placebo-controlled Phase II Trial (The JAPAN-PD Study), JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 43(4), 436-438, 201304
  40. Perineural Invasion in Extrahepatic Cholangiocarcinoma: Prognostic Impact and Treatment Strategies, JOURNAL OF GASTROINTESTINAL SURGERY, 17(8), 1429-1439, 201308
  41. Adjuvant chemotherapy with gemcitabine and S-1 after surgical resection for advanced biliary carcinoma: outcomes and prognostic factors, JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 19(4), 306-313, 201207
  42. Long-term results of adjuvant gemcitabine plus S-1 chemotherapy after surgical resection for pancreatic carcinoma, JOURNAL OF SURGICAL ONCOLOGY, 106(2), 174-180, 201208
  43. Elevation of Urine Trypsinogen 2 Is an Independent Risk Factor for Pancreatic Fistula After Pancreaticoduodenectomy, PANCREAS, 41(6), 876-881, 201208
  44. Histological Loss of Pancreatic Exocrine Cells Correlates With Pancreatic Exocrine Function After Pancreatic Surgery, PANCREAS, 41(6), 928-933, 201208
  45. Human Equilibrative Nucleoside Transporter 1 Expression Predicts Survival of Advanced Cholangiocarcinoma Patients Treated With Gemcitabine-Based Adjuvant Chemotherapy After Surgical Resection, ANNALS OF SURGERY, 256(2), 288-296, 201208
  46. Prognostic Significance of Telomerase Activity and Human Telomerase Reverse Transcriptase Expression in Ampullary Carcinoma, ANNALS OF SURGICAL ONCOLOGY, 19(9), 3072-3080, 201209
  47. Combined Analysis of Dihydropyrimidine Dehydrogenase and Human Equilibrative Nucleoside Transporter 1 Expression Predicts Survival of Pancreatic Carcinoma Patients Treated with Adjuvant Gemcitabine Plus S-1 Chemotherapy after Surgical Resection, ANNALS OF SURGICAL ONCOLOGY, 19, S646-S655, 201207
  48. A rare diagnostic challenge in acute appendicitis: a case report. Hiroshima J Med Sci. 2012 Mar;61(1):19-21., Hiroshima J Med Sci, 61(1), 19-21, 20120301
  49. Intrahepatic Cholangiocarcinoma: Clinicopathological Differences Between Peripheral Type and Hilar Type, JOURNAL OF GASTROINTESTINAL SURGERY, 16(3), 540-548, 201203
  50. Bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents--special references to bacteria isolated between April 2009 and March 2010, The Japanese Journal of Antibiotics, 64(3), 125-69, 20110601
  51. Ruptured left colic arterial aneurysm treated by transcatheter arterial embolization alone and without a subsequent laparotomy: Report of a case, SURGERY TODAY, 41(5), 707-712, 201105
  52. Edaravone, a Free Radical Scavenger, Promotes Engraftment of Intraportally Transplanted Islet Cells, PANCREAS, 40(1), 126-130, 201101
  53. Prognostic Factors After Surgical Resection for Intrahepatic, Hilar, and Distal Cholangiocarcinoma, ANNALS OF SURGICAL ONCOLOGY, 18(3), 651-658, 201103
  54. Is Para-aortic Lymph Node Metastasis a Contraindication for Radical Resection in Biliary Carcinoma?, WORLD JOURNAL OF SURGERY, 35(5), 1085-1093, 201105
  55. Prognostic Factors of Patients with Advanced Gallbladder Carcinoma Following Aggressive Surgical Resection, JOURNAL OF GASTROINTESTINAL SURGERY, 15(6), 1007-1016, 201106
  56. Impact of Intratumoral Thymidylate Synthase Expression on Prognosis After Surgical Resection for Ampullary Carcinoma, JOURNAL OF SURGICAL ONCOLOGY, 103(7), 663-668, 20110601
  57. Predictive risk factors for clinically relevant pancreatic fistula analyzed in 1,239 patients with pancreaticoduodenectomy: multicenter data collection as a project study of pancreatic surgery by the Japanese Society of Hepato-Biliary-Pancreatic Surgery, JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 18(4), 601-608, 201107
  58. Prognostic Impact of Dihydropyrimidine Dehydrogenase Expression on Pancreatic Adenocarcinoma Patients Treated With S-1-Based Adjuvant Chemotherapy After Surgical Resection, JOURNAL OF SURGICAL ONCOLOGY, 104(2), 146-154, 20110801
  59. Distal pancreatectomy with duct-to-mucosa pancreaticogastrostomy: a novel technique for preventing postoperative pancreatic fistula, AMERICAN JOURNAL OF SURGERY, 202(1), 77-81, 201107
  60. Clinical Pharmacokinetics of Meropenem and Biapenem in Bile and Dosing Considerations for Biliary Tract Infections Based on Site-Specific Pharmacodynamic Target Attainment, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 55(12), 5609-5615, 201112
  61. Reduced Pancreatic Parenchymal Thickness Indicates Exocrine Pancreatic Insufficiency After Pancreatoduodenectomy, JOURNAL OF SURGICAL RESEARCH, 171(2), 473-478, 201112
  62. Number of Metastatic Lymph Nodes, but Not Lymph Node Ratio, Is an Independent Prognostic Factor after Resection of Pancreatic Carcinoma, JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 211(2), 196-204, 201008
  63. Prognostic Impact of Para-aortic Lymph Node Metastasis in Pancreatic Ductal Adenocarcinoma, WORLD JOURNAL OF SURGERY, 34(8), 1900-1907, 201008
  64. Gemciatbine-based adjuvant chemotherapy improves survival after aggressive surgical resection for advanced biliary carcinoma, J Gastrointest Surg, 13(8), 1470-1479, 20090801
  65. Main pancreatic duct obstruction to asmall nonfunctioning endocrine tumor of the pancreas, Hiroshima J Med Sci, 58(1), 45-48, 20090101
  66. Usefulmness of human telomerase reverse transcriptase in pancreatic juice as a biomarker of pancreatic malignancy, Pancreas, 38(5), 527-533, 20090501
  67. Predictive factors for exocrine pancaretic insufficiency after oancreatoduedenectomy with pancreaticogastrectomy, J Gastrointest Surg, 13(7), 1321-1327, 20090701
  68. Changes in the agr locus affect enteritis caused by methcillin-resistant Staphylococcus aureus, J Clin Microbiol, 47(9), 1528-1535, 20090901
  69. Usefulness of a C-13-labeled mixed triglyceride breath test for assessing pancreatic exocrine function after pancreatic surgery, SURGERY, 145(2), 168-175, 200902
  70. Invasive Intraductal Papillary-Mucinous Neoplasm of the Pancreas: Comparison With Pancreatic Ductal Adenocarcinoma, JOURNAL OF SURGICAL ONCOLOGY, 100(1), 13-18, 20090701
  71. Impact of Adjuvant Gemcitabine Plus S-1 Chemotherapy After Surgical Resection for Adenocarcinoma of the Body or Tail of the Pancreas, JOURNAL OF GASTROINTESTINAL SURGERY, 13(1), 85-92, 200901
  72. Changes in the agr Locus Affect Enteritis Caused by Methicillin-Resistant Staphylococcus aureus, JOURNAL OF CLINICAL MICROBIOLOGY, 47(5), 1528-1535, 200905
  73. Analysis of Fat Digestive and Absorptive Function after Subtotal Gastrectomy by a C-13-Labeled Mixed Triglyceride Breath Test, DIGESTION, 80(2), 98-103, 2009
  74. Indication for Postoperative Adjuvant Therapy in Biliary Carcinoma Based on Analysis of Recurrence and Survival After Surgical Resection, DIGESTIVE DISEASES AND SCIENCES, 54(6), 1360-1364, 200906
  75. Predictive Factors for Exocrine Pancreatic Insufficiency After Pancreatoduodenectomy with Pancreaticogastrostomy, JOURNAL OF GASTROINTESTINAL SURGERY, 13(7), 1321-1327, 200907
  76. Usefulness of Human Telomerase Reverse Transcriptase in Pancreatic Juice as a Biomarker of Pancreatic Malignancy, PANCREAS, 38(5), 527-533, 200907
  77. Gemcitabine-Based Adjuvant Chemotherapy Improves Survival After Aggressive Surgery for Hilar Cholangiocarcinoma, JOURNAL OF GASTROINTESTINAL SURGERY, 13(8), 1470-1479, 200908
  78. Pouchitis disease activity index (PDAI) does not predict patients with symptoms of pouchitis who will respond to antibiotics, SURGERY TODAY, 39(11), 962-968, 200911
  79. Combination of Polyglicolic Acid Felt and Fibrin Glue for Prevention of Pancreatic Fistula Following Pancreaticoduodenectomy, HEPATO-GASTROENTEROLOGY, 56(94-95), 1538-1541, 2009
  80. Adjuvant Gemcitabine Plus S-1 Chemotherapy Improves Survival After Aggressive Surgical Resection for Advanced Biliary Carcinoma, ANNALS OF SURGERY, 250(6), 950-956, 200912
  81. Telomere shortening and telomerase expression during multistage carcinogenesis of intraductal papillary mucinous neoplasms of the pancreas, JOURNAL OF GASTROINTESTINAL SURGERY, 12(1), 17-28, 200801
  82. Detection of human telomerase reverse transcriptase (hTERT) expression in tissue and pancreatic juice from pancreatic cancer, SURGERY, 143(1), 113-125, 200801
  83. No mortality after 150 consecutive pancreatoduodenctomies with duct-to-mucosa pancreaticogastrostomy, JOURNAL OF SURGICAL ONCOLOGY, 97(3), 205-209, 20080301
  84. A soft pancreatic remnant is associated with increased drain fluid pancreatic amylase and serum CRP levels following pancreatoduodenectomy, JOURNAL OF GASTROINTESTINAL SURGERY, 12(1), 51-56, 200801
  85. Successful preoperative diagnosis of a rare bowel obstruction: Cecal volvulus, JOURNAL OF GASTROINTESTINAL SURGERY, 12(1), 202-204, 200801
  86. Postoperative adjuvant chemotherapy improves survival after surgical resection for pancreatic carcinoma, JOURNAL OF GASTROINTESTINAL SURGERY, 12(3), 534-541, 200803
  87. Prognostic impact of perineural invasion following pancreatoduodenectomy with lymphadenectomy for ampullary carcinoma, DIGESTIVE DISEASES AND SCIENCES, 53(8), 2281-2286, AUG 2008
  88. Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression, JOURNAL OF SURGICAL ONCOLOGY, 97(5), 469-475, 20080401
  89. Patient with perforation caused by emphysematous cholecystitis who showed flare on the skin of the right dorsal lumbar region and intraperitoneal free gas, JOURNAL OF HEPATO-BILIARY-PANCREATIC SURGERY, 15(2), 204-208, 200803
  90. Long-term pancreatic endocrine function following pancreatoduodenectomy with pancreaticogastrostomy, JOURNAL OF SURGICAL ONCOLOGY, 97(6), 519-522, 20080501
  91. An antecolic Roux-en Y type reconstruction decreased delayed gastric emptying after pylorus-preserving pancreatoduodenectomy, JOURNAL OF GASTROINTESTINAL SURGERY, 12(6), 1081-1086, 200806
  92. Adjuvant gemcitabine plus S-1 chemotherapy after surgical resection for pancreatic adenocarcinoma, AMERICAN JOURNAL OF SURGERY, 195(6), 757-762, 200806
  93. Randomized clinical trial to assess the efficacy of ulinastatin for postoperative pancreatitis following pancreaticoduodenectomy, JOURNAL OF SURGICAL ONCOLOGY, 98(5), 309-313, 20081001
  94. Prognostic significance of lymph node metastasis and surgical margin status for distal cholangiocarcinoma, JOURNAL OF SURGICAL ONCOLOGY, 95(3), 207-212, 20070301
  95. Pancreatoduodenectomy for distal cholangiocarcinoma: Prognostic impact of lymph node metastasis, WORLD JOURNAL OF SURGERY, 31(2), 337-344, 200702
  96. Predictive factors of malignant or invasive intraductal papillary-mucinous neoplasms of the pancreas, JOURNAL OF GASTROINTESTINAL SURGERY, 11(3), 338-344, 200703
  97. Specific antibiotic prophylaxis based on bile cultures is required to prevent postoperative infectious complications in pancreatoduodenectomy patients who have undergone preoperative biliary drainage, WORLD JOURNAL OF SURGERY, 31(11), 2230-2235, 200711
  98. A case of pancreatic solid-pseudopapillary tumor without cystic component in an elderly man., 103(11), 1288-95, 20060401
  99. Double intussusceptions in the small intestine caused by metastatic renal cell carcinoma: Report of a case, SURGERY TODAY, 36(1), 85-88, 200601
  100. Mucinous cystic neoplasm of the pancreas with ovarian-type stroma arising in the head of the pancreas: Case report and review of the literature, DIGESTIVE DISEASES AND SCIENCES, 51(3), 629-632, 200603
  101. Effect of antibiotic heterogeneity on the development of infections with antibiotic-resistant gram-negative organisms in a non-intensive care unit surgical ward, WORLD JOURNAL OF SURGERY, 30(7), 1269-1276, 200607
  102. Diffuse cerebral white matter T2-weighted hyperintensity: A new finding of general paresis, ACTA RADIOLOGICA, 47(6), 609-611, 200607
  103. Intraductal papillary-mucinous neoplasms and mucinous cystic neoplasms of the pancreas differentiated by ovarian-type stroma, SURGERY, 140(3), 448-453, 200609
  104. Relapsing acute pancreatitis due to ampullary adenoma in a patient with familial adenomatous polyposis, JOURNAL OF GASTROENTEROLOGY, 41(8), 798-801, 200609
  105. Hepatic regeneration promotes engraftment of intraportally transplanted islet cells., Surgery, 137, 612-619, 20050401
  106. Hepatic regeneration promotes engraftment of intraportally transplanted islet cells., surgery, 612-619, 20050601
  107. Intracellular cytokine patterns of peripheral blood T cells as a useful indicator of activeness of Crohn's disease., Hiroshima J Med Sci, 1-8, 20050301
  108. Attenuation of telomerase activity by hammerhead ribozymes targeting human telomerase RNA and telomerase reverse transcriptase in pancreatic carcinoma cells., Hiroshima J Med Sci, 21-27, 20050301
  109. Bacterial translocation: Not a clinically relevant phenomenon in colorectal cancer, WORLD JOURNAL OF SURGERY, 29(2), 198-202, 200502
  110. Duodenal cancer arising from the remaining duodenum after pylorus-preserving pancreatoduodenectomy for ampullary cancer in familial adenomatous polyposis, JOURNAL OF GASTROINTESTINAL SURGERY, 9(3), 389-392, 200503
  111. Hepatic regeneration promotes engraftment of intraportally transplanted islet cells, SURGERY, 137(6), 612-619, 200506
  112. Successful preoperative diagnosis and complete resection of biliary intraductal papillary-mucinous neoplasm of the liver, JOURNAL OF GASTROINTESTINAL SURGERY, 9(6), 860-862, 2005
  113. Systemic inflammatory response syndrome (SIRS) as a predictor of strangulated small bowel obstruction, Hepatogastroenterology, 51(59), 20040901
  114. Pancreatic metastasis of dermatofibrosarcoma protuberans, J. Gastroenterol., 39(8), 798-800, 20040801
  115. Pancreatic head resection with segmental duodenectomy for intraductal papillary mucinous tumors of the pancreas, J Gastrointest Surg, 8(6), 713-719, 20040601
  116. An evaluation of laparoscopic cholecystectomy after selective percutaneous transhepatic gallbladder drainage for acute cholecystitis, Gastrointest Endosc, 59(7), 839-844, 20040701
  117. Combined Assessment of beta- d-Glucan and Degree of Candida Colonization before Starting Empiric Therapy for Candidiasis in Surgical Patients, World J. Surg., 28(6), 625-630, 20040601
  118. Laparoscopic adhesiolysis for recurrent postoperative small bowel obstraction, Hepatogastroenterology, 51(58), 1058-1061, 20040701
  119. Celiac axis occlusion with replaced common hepatic artery and pancreatoduodenectomy, J Gastrointest Surg, 8(4), 520-522, 20040401
  120. Revascularization using splenic artery to right gastroepiploic artery graft during total pancreatectomy after coronary arterial bypass grafting, Surgery, 135(1), 118, 20040101
  121. Systemic inflammatory response syndrome (SIRS) as a predictor of strangulated small bowel obstruction., Hepatogastroenterology, 51, 1393-1396, 20041001
  122. Laparoscopic and open approach in perforated peptic ulcer., Hepatogastroenterology, 51, 1536-1539, 20040901
  123. An evaluation of laparoscopic cholecystectomy after selective percutaneous transhepatic gallbladder drainage for acute cholecystitis., Gastrointest Endosc, 59, 839-844, 20040601
  124. Celiac axis occlusion with replaced common hepatic artery and pancreatoduodenectomy, JOURNAL OF GASTROINTESTINAL SURGERY, 8(4), 520-522, 2004
  125. An evaluation of laparoscopic cholecystectomy after selective percutaneous transhepatic gallbladder drainage for acute cholecystitis, GASTROINTESTINAL ENDOSCOPY, 59(7), 839-844, 200406
  126. Laparoscopic adhesiolysis for recurrent postoperative small bowel obstruction, HEPATO-GASTROENTEROLOGY, 51(58), 1058-1061, 2004
  127. Combined assessment of beta-D-glucan and degree of Candida colonization before starting empiric therapy for candidiasis in surgical patients, WORLD JOURNAL OF SURGERY, 28(6), 625-630, 200406
  128. Systemic Inflammatory Response syndrome (SIRS) as a predictor of strangulated small bowel obstruction, HEPATO-GASTROENTEROLOGY, 51(59), 1393-1396, 2004
  129. Laparoscopic and open approach in perforated peptic ulcer, HEPATO-GASTROENTEROLOGY, 51(59), 1536-1539, 2004
  130. Pancreatic metastasis of dermatofibrosarcoma protuberans, JOURNAL OF GASTROENTEROLOGY, 39(8), 798-800, 200408
  131. Pancreatic head resection with segmental duodenectomy for intraductal papillary mucinous tumors of the pancreas, JOURNAL OF GASTROINTESTINAL SURGERY, 8(6), 713-719, 2004
  132. Adenosquamous carcinoma of the pancreas: preoperative diagnosis and molecular alterations, Journal of Gastroenterology, 38(12), 20031201
  133. Successful diagnosis and resection of icteric type hepatocellular carcinoma, Hepatogastroenterology, 50(53), 20030901
  134. Fluorescent-based BAT-26 analysis for distinct screening of microsatellite instability in colorectal cancers, INTERNATIONAL JOURNAL OF ONCOLOGY, 22(4), 20030401
  135. Laparoscopic and open approach in perforated peptic ulcer, Hepatogastroenterology, 51(59), 1536-1539, 20030901
  136. Fluorescent-based BAT-26 analysis for distinct screening of microsatellite instability in colorectal cancers, INTERNATIONAL JOURNAL OF ONCOLOGY, 22(4), 807-813, 200304
  137. Comparative analysis of K-ras point mutation, telomerase activity, and p53 overexpression in pancreatic tumours, ONCOLOGY REPORTS, 10(2), 277-283, 2003
  138. Successful diagnosis and resection of icteric type hepatocellular carcinoma, HEPATO-GASTROENTEROLOGY, 50(53), 1634-1636, 2003
  139. Adenosquamous carcinoma of the pancreas: preoperative diagnosis and molecular alterations, JOURNAL OF GASTROENTEROLOGY, 38(12), 1171-1175, 200312
  140. Changes in the intestinal flora after the administration of prophylactic antibiotics to patients undergoing a gastrectomy, Surgery Today, 32(7), 20020701
  141. Changes in the intestinal flora after the administration of prophylactic antibiotics to patients undergoing a gastrectomy, SURGERY TODAY, 32(7), 581-586, 2002
  142. Long-term results of seton drainage on complex anal fistulae in patients with Crohn's disease, JOURNAL OF GASTROENTEROLOGY, 37(11), 912-915, 200211
  143. Bacterial translocation in patients with Crohn's disease undergoing surgery, DISEASES OF THE COLON & RECTUM, 45(12), 1665-1671, 200212
  144. Successful pre-operative diagnosis of malignant intraductal papillary mucinous tumor of the pancreas by detecting telomerase activity, JOURNAL OF GASTROINTESTINAL CANCER, 31(1-3), 117-121, 2002
  145. HUGE RETROPERITONEAL SARCOMA : A CASE REPORT, 63(10), 557-560, 20011001
  146. Gut transit time after ileal pouch-anal anastomosis using a radiopaque marker, Diseases of the Colon and Rectum, 44(12), 20011201
  147. Gut transit time after ileal pouch-anal anastomosis using a radiopaque marker, DISEASES OF THE COLON & RECTUM, 44(12), 1808-1813, 200112
  148. A brief course of colon preparation with oral antibiotics., Surgery Today, 30(1), 112-116, 20000201
  149. Progression of primary biliary cirrhosis after proctocolectomy for ulcerative colitis., J. Gastroenterol., 35(6), 870-872, 20000601
  150. Generation of pro-Inflammatory and anti-Inflammatory cytokines In the gut In zymosan-Induced peritonitis., Hiroshima J. Med. Sci., 49(1), 43-48, 20000101
  151. High Telomerase Activity Is an Independent Prognostic Indicator of Poor Outcome in Colorectal Cancer., Clinical Cancer Research, 6(10), 2696-2701, 20001001
  152. Long-term survival of peripheral intrahepatic cholangiocarcinoma with metastasis to the para-aortic lymph nodes., Surgery, 126(1), 105-106, 20000101
  153. High Telomerase Activity Is an Independent Prognostic Indicator of Poor Outcome in Colorectal Cancer, Clinical Cancer Research, 6, 2696-2701, 20000701
  154. Progression of primary biliary cirrhosis after proctocolectomy for ulcerative colitis, J. Gastroenterol., 35, 870-872, 20001101
  155. Generation of pro-inflammatory and anti-inflammatory cytokines in the gut in zymosan-induced peritonitis, Hiroshima Journal of Medical Science, 49(1), 43-48, 20000301
  156. Long-term survival of peripheral intrahepatic cholangiocarcinoma with metastasis to the para-aortic lymph nodes., Surgery, 126, 105-106, 20000101
  157. A brief course of colon preparation with oral antibiotics., Surgery Today, 30(2), 112-116, 20000201
  158. Long-term survival of peripheral intrahepatic cholangiocarcinoma with metastasis to the para-aortic lymph nodes, SURGERY, 127(1), 105-106, 200001
  159. A brief course of colon preparation with oral antibiotics, SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY, 30(2), 112-116, 2000
  160. High telomerase activity is an independent prognostic indicator of poor outcome in colorectal cancer, CLINICAL CANCER RESEARCH, 6(7), 2696-2701, 200007
  161. Progression of primary biliary cirrhosis after proctocolectomy for ulcerative colitis, JOURNAL OF GASTROENTEROLOGY, 35(11), 870-872, 200011
  162. Strictureplasty for short duodenal stenosis in Crohn's disease, JOURNAL OF GASTROENTEROLOGY, 35(12), 929-932, 200012
  163. Lack of CD44 variant 6 expression in advanced extrahepatic bile duct / ampullary carcinoma., Cancer, 86(9), 1691-1699, 19990901
  164. An additional dose of cefazolin for intraoperative prophylaxis., Surgery Today, 29(4), 1233-1236, 19990401
  165. Chenges in intestinal flora after administration of panipenem/betamipron or aulbactam/cefoperazone for treatment of postoperative infection in gastrectomy patients., J Infect Chemother, 5(1), 52-57, 19990101
  166. The effectiveness of perineal rectosigmoidectomy for the treatment of rectal prolapse in elderly and high-risk patients., Surgery Today, 29(3), 290-293, 19990601
  167. Surgical approaches for pancreatic ascites: report of three cases., Surgery Today, 29(3), 458-461, 19990601
  168. Surgical approaches for pancreatic ascites: report of three cases, Surg Today, 29, 458-461, 19990501
  169. An additional dose of cefazolin for intraoperative prophylaxis, Surgery Today, 29, 1233-1236, 19991201
  170. Lack of CD44 variant 6 expression in advanced extrahepatic bile duct/ampullary carcinoma., Cancer, 86(9), 1691-1699, 19991101
  171. Surgical approachs for pancreatic ascites: report of three cases, Surgery Today, 29(5), 458-461, 19990501
  172. Prediction for the development of postoperative infections in the operation of esophageal cancer compared with gastric surgery., Hiroshima J. Med. Sci., 47(1), 109-113, 19980101
  173. Influence of ileal pouch capacity and anal sphincteric function on the clinical outcome after ileal pouch-anal anastomosis., Surgery Today, 25(2), 392-397, 19970401
  174. Teromerase activity for the preoperative diagnosis of pancreatic cancer., J ournal of the National Cancer Institute, 89(21), 1621-1623, 19971001
  175. Postoperative enteritis caused by methicillin-resistant Sthaphylococcus aureus., Surgery Today, 27(4), 816-825, 19970801
  176. Endogenous M-CSF and alteration in monocyte phenotypes in the patients with SIRS., The Immune Consequences of Trauma= Shock and Sepsis, 371-376, 19970301
  177. Telomerase activity for the preoperative diagnosis of pancreatic cancer, J. Natl. Cancer Inst., 89(21), 1621-1623, 19971101
  178. Postoperative enteritis caused by methicillin-resistant Sthaphylococcus aureus, Surgery Today, 27, 816-825, 19970901
  179. Telomerase activity for the preoperative diganosis of pancreatic cancer, J ournal of the National Cancer Institute, 89(21), 1621-1623, 19971101
  180. Sihnificance of peripferal pulymorphonucleat lenkocyte counts in the early period after gastrointestinal surgery -Wich reference to serum cytokine levels and Organ dysfunction-, The Japanese Journal of Gastroeeeorlogical Surgery, 29(1), 63-69, 19960401
  181. G-CSF, Surgery Frontier, 3(2), 212-213, 19960401
  182. Are serum IL-8 levels a useful predictor of subsequent organ dysfunction?, Surgical trauma & immunological responses, 4(1), 27-29, 19950401
  183. Host response in patients with ahdominal emergency-changes and significance of serum cytokine levels and neutrophil counts-, Jourral of Abdomimal Emergency Medicine, 15(6), 1069-1075, 19950401
  184. Mechanism and prevention of sereve SIRS., Intersive & Critical Care Medicine, 7(12), 1267-1273, 19950401
  185. Telomerase activity in gastric cancer, Cancer Res., 55(15), 3258-3262, 19950801
  186. Mac-1 expression and superoxide generation of the peripheral polymorphonuclear leukocyte following gastrectomy and esophagectomy., Hiroshima J. Med. Sci., 44(2), 39-46, 19950201
  187. Severity and predicted outcome of postoperative Pseudomonas aeruginosa infections., Surgery Today, 25(3), 672-678, 19950601
  188. Telomerase activity in gastric cancer., Cancer Res., 55(12), 3258-3262, 19951201
  189. Postoperative enteritis caused by methicillin-resistent Staphylococcus aureus., Surgery Today, 27(4), 816-825, 19950801
  190. Severity and predicted outcome of postoperative Pseudomonas aeruginosa infections, Surgery Today, 25, 672-678, 19950801
  191. Telomerase activity in gastric cancer, Cancer Research, 55(8), 3258-3262, 19950801
  192. Mac-1 expression and superoxide generation of the peripheral polymorphonuclear leukocyte following gastrectomy and esophagectomy, Hiroshima Journal of Medical Science, 44(2), 39-46, 19950601
  193. Defecation mechanisms in conscious dogs after total colectomy with ileorectal anastomosis., J Am Coll Surg, 178(3), 249-256, 19940301
  194. Defecation mechanisms in conscious dogs after total colectomy with ileorectal anastomosis, Journal of the American College of Surgeons, 178(3), 249-256, 19940301
  195. Changes in Grannlocyte. functions and significance of levels of serum granulocyte. colony-stimulating factor after surgery for esophageal. cancer, The Japanese Journal of Gastroenterological Surgery, 26(11), 2561-2566, 19930401
  196. Mucin-producing pancreatic tumors : A sendy of nuclear DNA content by slow cytometry, Surgery Today, 23, 491-495, 19930401
  197. Changes in neutrophil function and serum G-CSF and IL-8 levels after surgery for esophageal cancer., Surgical trauma & immunological responses, 9(1), 26-28, 19930401
  198. A study on postoperative enteriris caused by methicillin-resistant Staphylococcus aureus., Surgery Today, 23(1), 4-8, 19930101
  199. 1994, 54(6), 1532-1536, 19930601
  200. Mucin-producing pancreatic tumors: A study of nuclear DNA content by flow cytometry., Surgery Today, 23(2), 491-495, 19930401
  201. Diagnosis of neoplastic pancreatic cysts, Journal of Japanese Society for Clinical Surgery., 53(7), 1566-1572, 19920401
  202. Anomalous arrangement of the pancreaticobiliary ductal system without dilatation of the biliary tract., Surgery Today, 22(2), 276-279, 19920401
  203. Clinicopathological sendies of polypoid lesions of the gallbladder., The Japanese Journal of Gastroenterological Surgery, 24(12), 2944-2950, 19910401
  204. The influence of clinical use of antobiotics on the sensitivity of strains isolated from postoperative infections.-A comparison of nosocomial pathogens with strains isolated from the bacterial flora of patients.-, Jpn J Surg, 21(4), 376-380, 19910801
  205. Toxin involvement in methicillin-resistant Staphylococcus aureus enteritis in gastroenterological surgery., Gastroenterologia Japonica, 26(6), 716-720, 19910601
  206. Methcillin-resistant Staphylococcus aureus in nosocomial infections in the surgical ward and operating room., Hiroshima J. Med. Sci., 38(4), 183-186, 19890401
  207. Mucin-producing pancreatic tumors: A study of nuclear DNA content by flow cytometry, Surgery Today, 23, 491-495
  208. Anomalous arrangement of the pancreaticobiliary ductal system without dilatation of the biliary tract, Surgery Today, 22, 276-279
  209. Revascularization using splenic artery to right gastroepiploic artery graft during total pancreatectomy after coronary arterial bypass grafting, Surgery
  210. Hand-assisted laparoscopic restorative proctocolectomy for ulcerative colitis, WORLD JOURNAL OF GASTROINTESTINAL SURGERY, 8(8), 578-582, 20160827
  211. Survival impact of neoadjuvant gemcitabine plus S-1 chemotherapy for patients with borderline resectable pancreatic carcinoma with arterial contact, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 79(1), 37-47, 201701
  212. Sarcopenia is closely associated with pancreatic exocrine insufficiency in patients with pancreatic disease, PANCREATOLOGY, 17(1), 70-75, 2017
  213. Comparison of the prognostic impact of pre- and post-operative CA19-9, SPan-1, and DUPAN-II levels in patients with pancreatic carcinoma, PANCREATOLOGY, 17(1), 95-102, 2017
  214. Randomized clinical trial of duct-to-mucosa pancreaticogastrostomy versus handsewn closure after distal pancreatectomy, BRITISH JOURNAL OF SURGERY, 104(5), 536-543, 201704
  215. A phase 1 study of gemcitabine/nab-paclitaxel/S-1 (GAS) combination neoadjuvant chemotherapy for patients with locally advanced pancreatic adenocarcinoma, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 79(4), 775-781, 201704
  216. Prognostic impact of normalization of serum tumor markers following neoadjuvant chemotherapy in patients with borderline resectable pancreatic carcinoma with arterial contact, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 79(4), 801-811, 201704
  217. Impact of Secreted Protein Acidic and Rich in Cysteine (SPARC) Expression on Prognosis After Surgical Resection for Biliary Carcinoma, JOURNAL OF GASTROINTESTINAL SURGERY, 21(6), 990-999, 201706
  218. A case of mixed adeno-neuroendocrine carcinoma with liver metastasis of neuroendocrine tumor component after adjuvant chemotherapy: a case report and literature review, Suizo, 32(4), 752-759, 2017
  219. Preservation of pancreatic endocrine and exocrine function of patients who underwent pancreatic resection, Suizo, 32(4), 706-713, 2017
  220. Survival impact of neoadjuvant gemcitabine plus S-1 chemotherapy for patients with borderline resectable pancreatic carcinoma with arterial contact, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 79(1), 37-47, 2017
  221. Prognostic impact of normalization of serum tumor markers following neoadjuvant chemotherapy in patients with borderline resectable pancreatic carcinoma with arterial contact, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 79(4), 801-811, 2017
  222. Impact of Secreted Protein Acidic and Rich in Cysteine (SPARC) Expression on Prognosis After Surgical Resection for Biliary Carcinoma., Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 21(6), 2017
  223. Prognostic impact of normalization of serum tumor markers following neoadjuvant chemotherapy in patients with borderline resectable pancreatic carcinoma with arterial contact., Cancer chemotherapy and pharmacology, 79(4), 2017
  224. Sarcopenia is closely associated with pancreatic exocrine insufficiency in patients with pancreatic disease, PANCREATOLOGY, 17(1), 70-75, 2017
  225. Comparison of the prognostic impact of pre- and post-operative CA19-9, SPan-1, and DUPAN-II levels in patients with pancreatic carcinoma, PANCREATOLOGY, 17(1), 95-102, 2017
  226. A phase 1 study of gemcitabine/nab-paclitaxel/S-1 (GAS) combination neoadjuvant chemotherapy for patients with locally advanced pancreatic adenocarcinoma, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 79(4), 775-781, 2017
  227. Impact of Secreted Protein Acidic and Rich in Cysteine (SPARC) Expression on Prognosis After Surgical Resection for Biliary Carcinoma, JOURNAL OF GASTROINTESTINAL SURGERY, 21(6), 990-999, 2017
  228. Pharmacokinetics of piperacillin-tazobactam in plasma, peritoneal fluid and peritoneum of surgery patients, and dosing considerations based on site-specific pharmacodynamic target attainment, INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 50(3), 393-398, 2017
  229. Retrospective Study of the Correlation Between Pathological Tumor Size and Survival After Curative Resection of T3 Pancreatic Adenocarcinoma: Proposal for Reclassification of the Tumor Extending Beyond the Pancreas Based on Tumor Size, WORLD JOURNAL OF SURGERY, 41(11), 2867-2875, 2017
  230. Effect of Neoadjuvant Nab-Paclitaxel plus Gemcitabine Therapy on Overall Survival in Patients with Borderline Resectable Pancreatic Cancer: A Prospective Multicenter Phase II Trial (NAC-GA Trial), ONCOLOGY, 93(5), 343-346, 2017
  231. Reinforced staplers for distal pancreatectomy, LANGENBECKS ARCHIVES OF SURGERY, 402(8), 1197-1204, 2017

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI, 2015, 2017
  2. KAKENHI, 2012, 2014
  3. KAKENHI, Analysis of telomere and telomerase activation mechanism in pancreatic neoplasms for molecularly targeted therapy, 2009, 2011
  4. KAKENHI, Clarification of promoting effect on engraftment of intraportally transplanted islet cells under hepatic regeneration, 2005, 2006
  5. KAKENHI, Does hepatic regeneration promotes engraftment of intraportally transplanted islet cells?, 2004, 2005
  6. KAKENHI, 2001, 2001
  7. KAKENHI, A STUDY ON CARCINOGENESIS OF THE PANCREATIC CANCER AND BIOMARKERS FOR ERALY DIAGNOSIS OF THE PANCREATIC CANCER, 2000, 2001

Social Activities

Organizing Academic Conferences, etc.

  1. 2017/10, 2017/10