Manabu Asakawa

Last Updated :2020/08/03

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Professor
E-mail
asakawahiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Doctor of Philosophy, HOKKAIDO UNIVERSITY
  • Master, HOKKAIDO UNIVERSITY

Research Fields

  • Agricultural sciences;Applied aquatic science;Aquatic life science

Research Keywords

  • Prostaglandin
  • dinoflagellate
  • Tetrodotoxin
  • Domoic Acid
  • Paralytic Shellfish Poison

Educational Activity

Course in Charge

  1. 2020, Liberal Arts Education Program1, 1Term, Life, food, and environmental sciences
  2. 2020, Liberal Arts Education Program1, 3Term, Food safety and health science
  3. 2020, Liberal Arts Education Program1, 3Term, Sport fishing and science: fishes-human beings interactions
  4. 2020, Undergraduate Education, 3Term, Seafood Chemistry and Biochemistry
  5. 2020, Undergraduate Education, 1Term, Introduction to Applied Biological Sciences
  6. 2020, Undergraduate Education, Intensive, Laboratory Work in General Physics
  7. 2020, Undergraduate Education, 2Term, Reading of Foreign Literature
  8. 2020, Undergraduate Education, Intensive, Laboratory Work in Marine Bioresources Chemistry
  9. 2020, Undergraduate Education, Academic Year, Graduation Thesis
  10. 2020, Undergraduate Education, Intensive, Training for Marine Food Processing
  11. 2020, Undergraduate Education, Intensive, (AIMS) Modern Food Science
  12. 2020, Undergraduate Education, 3Term, Modern Food Science
  13. 2020, Graduate Education (Master's Program) , OutOfTerm(1st), Aquatic Toxicology
  14. 2020, Graduate Education (Master's Program) , OutOfTerm(1st), Hygienic Chemistry of Sea Food
  15. 2020, Graduate Education (Master's Program) , 1Term, Exercises in Food andAgriLife Science A
  16. 2020, Graduate Education (Master's Program) , 2Term, Exercises in Food andAgriLife Science A
  17. 2020, Graduate Education (Master's Program) , 3Term, Exercises in Food andAgriLife Science B
  18. 2020, Graduate Education (Master's Program) , 4Term, Exercises in Food andAgriLife Science B
  19. 2020, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Food andAgriLife Science
  20. 2020, Graduate Education (Master's Program) , 2Term, Bioactive Natural Products Chemistry I
  21. 2020, Graduate Education (Master's Program) , 4Term, Bioactive Natural Products Chemistry II

Research Activities

Academic Papers

  1. Free amino-acid composition of a red algal species (Digenea simplex) containing neuroexcitotoxic kainic acid from Ishigaki Island, Okinawa Prefecture, Japan, Toxicon, 177(Supplement 1), 46, 2020 July 9
  2. Paralytic Shellfish Poison (PSP) Profiles and Toxification of Short-necked Clams Fed with the Toxic Dinoflagellate Alexandrium tamarense, Journal of the Food Hygienics Society of Japan, 46(6), 251-255, 20050215
  3. Studies on Paralytic Shellfish Poison (PSP) Toxification of Bivalves in Association with Appearance of Alexandrium tamarense in Hiroshima Bay, Hiroshima Prefecture, Journal of the Food Hygienics Society of Japan, 34(1), 50-54, 19930401
  4. Occurrence of Paralytic Shellfish Poison (PSP)-Producing Dinoflagellate Alexandrium tamarense in Hiroshima Bay, Hiroshima Prefecture, Japan, during 1993-2004 and Its PSP Profiles, Journal of the Food Hygienics Society of Japan, 46(6), 246-250, 20050201
  5. Toxicity Change of Paralytic Shellfish Poisom-in Fested Oyster during Canning, Drying and Sauce-making Processes, Journal of the Food Hygienics Society of Japan, 36(1), 35-41, 19950401
  6. Occurrence of paralytic shellfish poison in the starfish Asterias amurensis in Kure Bay, Hiroshima Prefecture, Japan, Toxicon, 35(7), 1081, 19970401
  7. Isolation and characterization of bacteria from the copepod ectoparasitic on the panther pufferTakifugu pardalis with the emphasis on TTX, Toxicon, 50, 779-790, 20071031
  8. PSP-toxification of the carnivorous gastropod Rapana venosa inhabiting the estuary of Nikoh River, Hiroshima Bay, Hiroshima Prefecture, Japan, Marine Pollution Bulletin, 48, 1116-1121, 20040401
  9. Survey of Food Poisoning Incidents in Japan Due to Ingestion of Marine Boxfish, along with Their Toxicity, JOURNAL OF THE FOOD HYGIENIC SOCIETY OF JAPAN, 50(5), 270-277, 20091001
  10. Paralytic toxins in a ribbon worm Cephalothrix species (Nemertean) adherent to cultured oysters in Hiroshima Bay, Hiroshima Prefecture, Japan, TOXICON, 38(6), 763-773, 36678
  11. Paralytic toxicity in the ribbon worm Cephalothrix species (Nemertea) in Hiroshima Bay, Hiroshima Prefecture, Japan and the isolation of tetrodotoxin as a main component of its toxins, TOXICON, 41(7), 747-753, 42889
  12. Occurrence of PSP-producing dinoflagellate Alexandrium tamiyavanichii in Bingo-Nada, the central coastal water of the Seto Inland Sea, Hiroshima Prefecture, Japan, MARINE POLLUTION BULLETIN, 56(4), 758-763, 42833
  13. Urgent topics on tropical and subtropical poisonous fishes and toxic benthic dinoflagellates, NIPPON SUISAN GAKKAISHI, 74(5), 908-908, 42986
  14. Developmental stages and growth of Pseudocaligus fugu Yamaguti, 1936 (Copepoda: Siphonostomatoida: Caligidae) host-specific to Puffer, JOURNAL OF NATURAL HISTORY, 43(29-30), 1779-1804, 2009
  15. STRUCTURE OF THE TOXIN ISOLATED FROM CARP (CYPRINUS CARPIO) BILE, Toxicin, 28(9), 1063-1069, 19900401
  16. Occurrence of Gonyautoxin-8 and Its Epimer in Toxic Plankton Protogonyaulax tamarensis from Funka Bay, Hokkaido, EISEI KAGAKU, 30(5), 328-331, 19840401
  17. Studies on the Conversion of Paralytic Shellfish Poisn (PSP) by Biochemical Reducing Agents, EISEI KAGAKU, 33, 1, 19870401
  18. Studies on the chemical Reductive Conversion of Paralytic Shellfish Poison Components, EISEI KAGAKU, 32, 3, 19860401
  19. Dinoflagellate Alexandrium tamarense as the source of Paralytic Shellfish Poison (PSP) contained in Bivalves from Hiroshima Bay, Hiroshima Prefecture, Japan, Toxicon, 33(5), 691-697, 19950401
  20. Phosphorylation of the Sendai virus M protein is not essential for virus replication either in vitro or in vivo., Virology, 235, 360-366, 19970401
  21. Tetrodotoxin and its related substances in the ribbon worm identified as undescribed species of the genus Proceohalothrix in Hiroshima Bay,Hiroshima Prefecture, Japan., Proceedings of 12th World Congress on Animal= Plant and Microbial Toxins, 18-22, 20000901
  22. Poisoning by red alga ’Ogonori’ (Gracilaria verrucosa) on the Nojima coast, Yokohama, Kanagawa prefecture, Japan., Journal of the Food Hygienics Society of Japan, 32(12), 1533-1538, 19941201
  23. Quantitative relationship between PSP components of Protogonyaulax tamarensis and of scallops from Funka Bay, Hokkaido., Bull. Fac. Fish. Hokkaido Univ., 34, 345-349, 19831201
  24. First occurrence of Alexandrium catenella in Funka Bay, Hokkaido, along with its unique toxin composition, Toxic Marine Phytoplankton, 439-498, 19900401
  25. Isolation of a toxin from carp (Cyprinus carpio) bile, J. Food Hyg.Soc. Japan, 31, 222-226, 19900401
  26. Paralytic toxins in a ribbon worm Cephalothrix species (Nemertean) adherent to cultured oysters in Hiroshima Bay, Hiroshima Prefecture, Japan, Toxicon, 38, 763-773, 20000401
  27. Occurrence of paralytic shellfish poison (PSP) in the starfish Asteria pectinifera collected from the Kure Bay, Hiroshima Prefecture, Japan, Toxicon, 41, 291-295, 20030401
  28. Paralytic toxicity in the ribbon worm Cephalothrix species (Nemertea) in Hiroshima Bay, Hiroshima Prefecture, Japan and the isolation of tetrodotoxin as a main component of its toxins, Toxicon, 41, 747-753, 20030401
  29. Mouse bioassay and partial characterization of the toxic substance in Caulerpa lentillifera, UPV J. Nat. Sci., 12, 75-82, 20070101
  30. Occurrence of PSP-Producing dinoflagellate Alexandrium tamiyavanichii in Bingo-Nada, the central coastal water of the Seto Inland Sea, Hiroshima Prefecture, Japan, Mar. Pollut. Bull., 56, 758-763, 20080401
  31. Isolation and characterization of bacteria from the copepod Pseudocaligus fugu ectoparasitic on the panther puffer Takifugu pardalis wth the emphasis on TTX, Toxicon, 50, 779-790, 20070705
  32. Detection of tetrodotoxin (TTX) from two copepods infecting the grass puffer Takifugu niphobles: TTX attracting the parasites?, Toxicon, 48, 620-626, 20060620
  33. Accumulation of tetrodotoxin (TTX) in Pseudocaligus fugu, a parasitic copepod from panther puffer Takifugu pardalis, but without vertical transmission-using an immunoenzymatic technique, Toxicon, 48, 116-122, 20060419
  34. Accumulation of Paralytic Shellfish Poison (PSP) and Biotransformation of Its Components in Oysters Crassostrea gigas Fed with the Toxic Dinoflagellate Alexandrium tamarense, Journal of the Food Hygienics Society of Japan, 47(1), 28-32, 20050316
  35. Occurrence of paralytic shellfish poison (PSP) in the starfish Asterina pectinifera collected from the Kure Bay, Hiroshima Prefecture, Japan, TOXICON, 41(3), 291-295, MAR 1 2003
  36. PSP-toxicification of the carnivorous gastropod Rapana venosa inhabiting the estuary of Nikoh River, Hiroshima Bay, Hiroshima Prefecture, Japan, MARINE POLLUTION BULLETIN, 48(43051), 1116-1121, 42890
  37. Immunoenzymatic visualization of tetrodotoxin (TTX) in Cephalothrix species (Nernertea : Anopla : Palaeonemertea : Cephalotrichidae) and Planocera reticulata (Platyhelminthes : Turbellaria : Polycladida : Planoceridae), TOXICON, 44(5), 515-520, 43012
  38. Occurrence of paralytic shellfish poison (PSP)-producing dinoflagellate Alexandrium tamarense in Hiroshima Bay, Hiroshima Prefecture, Japan, during 1993-2004 and its PSP profiles, JOURNAL OF THE FOOD HYGIENIC SOCIETY OF JAPAN, 46(6), 246-250, 43074
  39. Paralytic shellfish poison (PSP) profiles and toxification of short-necked clams fed with the toxic dinoflagellate Alexandrium tamarense, JOURNAL OF THE FOOD HYGIENIC SOCIETY OF JAPAN, 46(6), 251-255, 43074
  40. Accumulation of paralytic shellfish poison (PSP) and biotransformation of its components in oysters Crassostrea gigas fed with the toxic dinoflagellate Alexandrium tamarense, JOURNAL OF THE FOOD HYGIENIC SOCIETY OF JAPAN, 47(1), A28-A32, 42772
  41. Detection of tetrodotoxin (TTX) from two copepods infecting the grass puffer Takifugu niphobles: TTX attracting the parasites?, TOXICON, 48(6), 620-626, 43045
  42. Highly Toxic Ribbon Worm Cephalothrix simula Containing Tetrodotoxin in Hiroshima Bay, Hiroshima Prefecture, Japan, TOXINS, 5(2), 376-395, 42779
  43. Taxonomic Identity of a Tetrodotoxin-Accumulating Ribbon-worm Cephalothrix simula (Nemertea: Palaeonemertea): A Species Artificially Introduced from the Pacific to Europe, ZOOLOGICAL SCIENCE, 30(11), 985-997, 43052
  44. Food Poisonings by Ingestion of Cyprinid Fish, TOXINS, 6(2), 539-555, 42780
  45. Partial biochemical characterization of egg masses of the wedge seahare Dolabella auricularia (Lighfoot, 1786), Tropical Technology Journal, 19(1), 201508
  46. Toxicity and Toxin Composition of the Greater Blue-Ringed Octopus Hapalochlaena lunulata from Ishigaki Island, Okinawa Prefecture, Japan, Toxins, 11, 245, 2019, April, 29

Publications such as books

  1. 2015, Marine Protists Diversity and Dynamics, Chapter 24 Paralytic Shellfish Poison (PSP)-Producing Dinoflagellate and PSP-Infested Organisms, paralytic shellfish Poison, Springer, 2015, English, Manabu Asakawa, Gloria Gomez-Delan, Mercy Barte-Quilangtang, Katsutoshi Ito, 978-4-431-55129-4, 648, 567
  2. 2020/04, Handbook of Algal Science, Technology and Medicine, The intoxication mechanism of xanthid crabs and edible shore crabs in Japan by paralytic shellfish toxin and/or tetrodotoxin was investigated., Chapter 36 - Different intoxication mechanism between paralytic shellfish toxin (PST)- and/or tetrodotoxin-contaminated xanthid crabs and PST-contaminated edible shore crabs in Japan and their food poisonings, paralytic shellfish toxin, xanthid crab, Elsevier Academic Press, 2020, 04, English, Tamao Noguchia, Osamu Arakawab, Kinue Daigo, Hiroshi Oikawac, Manabu Asakawad, Keisuke Miyazawa, 978-0-12-818305-2, 738, 15
  3. 1990/06, FIRST OCCURRENCE OF ┣DBALEXANDRIUM(/)-┫DB ┣DBCATENELLA(/)-┫DB IN FUNKA BAY, HOKKAIDO, ALONG WITH ITS UNIQUE TOXIN, Toxic Marine Phytoplankton, 1990, E, 204
  4. 1992/03, Paralytic Shellfish Poison in Marine Fouling Organisms, EMERGING FOOD SAFETY PROBLEM RESULTING FROM MICROBIAL CONTAMINATION, 1992, E
  5. CHROMATOGRAPHY, Instrumental Analysis of Tetrodotoxin, INTECH, 2012, 10, English, M.Asakawa, Y.Shida, K.Miyazawa, T.Noguchi, 978-953-51-0813-9, 428, 26

Invited Lecture, Oral Presentation, Poster Presentation

  1. Free amino acid composition of a red algal species (Digenea simplex) containing neuroexitotoxic kainic acid from Ishigaki Island, Okinawa Prefecture, Japan, Manabu Asakawa, Gloria Gomez Delan, Tamao Noguchi, Susumu Ohtsuka, 20th World Congress of the International Society on Toxinology, 2019/09/08, Without Invitation, International Society of Toxinology, Buenos Aires
  2. Toxicity and toxins of the greater blue-ringed octopus Hapalochlaena lunulata from Ishigaki Island, Okinawa Prefecture, Japan, Manabu Asakawa, Miwako Fujii, Satoshi Tomano, Susumu Otsuka, Miyuki Yamauchi, Kohei Umezaki, Kyoichiro Kaneko, Takuya Matsumoto, Takuya Matsumoto, 10th Global Summit on Toxicology & Applied Pharmacology, 2017/07/20, Without Invitation, International Society of Toxicology, Chicago, USA
  3. Marine Biotoxins: Occurrence, Toxicity, and Detection Methods., Manabu Asakawa, International Conference on Food Safety and Engineering, 2016/10/19, With Invitation

Social Activities

History as Peer Reviews of Academic Papers

  1. 2019, Toxins, reviewer, 5
  2. 2014, Food Hygiene and Safety Science
  3. 2014, TOXINS
  4. 2016, TOXICON, Reviewer, 1
  5. 2019, Toxins, Special Issue, "Isolation and Characterization of Marine Toxins", Guest Editor