Masao Kobayashi

Last Updated :2017/11/01

Affiliations, Positions
Graduate School of Biomedical & Health Sciences (Biomedical Sciences Major), Professor
E-mail
masakhiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Doctor of Philosophy in Medical Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Pediatrics

Research Keywords

  • Function
  • Hematopoietic progenitor cell
  • neutropenia
  • nursing
  • Malignency
  • Phagocytes
  • hematopoietic stem cell transplantation

Educational Activity

Course in Charge

  1. 2017, Undergraduate Education, Intensive, Systemic Disease Control
  2. 2017, Undergraduate Education, Intensive, Practice for medical research
  3. 2017, Undergraduate Education, Intensive
  4. 2017, Undergraduate Education, Intensive, Clinical Clerkship (Advanced Course)
  5. 2017, Undergraduate Education, First Semester, Pediatrics
  6. 2017, Undergraduate Education, First Semester, Pediatrics
  7. 2017, Graduate Education (Master's Program) , First Semester, Special Course of Biomedical Technology and Informatics
  8. 2017, Graduate Education (Doctoral Program) , First Semester, Advanced seminar on Pediatrics
  9. 2017, Graduate Education (Doctoral Program) , Second Semester, Advanced seminar on Pediatrics
  10. 2017, Graduate Education (Doctoral Program) , First Semester, Advanced research on Pediatrics
  11. 2017, Graduate Education (Doctoral Program) , Second Semester, Advanced research on Pediatrics
  12. 2017, Graduate Education (Doctoral Program) , First Semester, Child health

Research Activities

Academic Papers

  1. Recurrence of Epileptic Spasms as Reflex Seizures Induced by Eating: A Case Report and Literature Review, NEUROPEDIATRICS, 48(2), 119-122, APR 2017
  2. Adipsic hypernatremia without hypothalamic lesions accompanied by autoantibodies to subfornical organ, BRAIN PATHOLOGY, 27(3), 323-331, MAY 2017
  3. Molecular mechanism and structural basis of gain-of-function of STAT1 caused by pathogenic R274Q mutation, JOURNAL OF BIOLOGICAL CHEMISTRY, 292(15), 6240-6254, APR 14 2017
  4. Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 140(1), 223-231, JUL 2017
  5. Alanine-scanning mutagenesis of human signal transducer and activator of transcription 1 to estimate loss- or gain-of-function variants, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 140(1), 232-241, JUL 2017
  6. Development of cystic malacia after high-dose cranial irradiation of pediatric CNS tumors in long-term follow-up, CHILDS NERVOUS SYSTEM, 33(6), 957-964, JUN 2017
  7. Clinical utility of next-generation sequencing for inherited bone marrow failure syndromes, GENETICS IN MEDICINE, 19(7), 796-802, JUL 2017
  8. A Case with Spondyloenchondrodysplasia Treated with Growth Hormone, FRONTIERS IN ENDOCRINOLOGY, 8, JUL 10 2017
  9. Late-onset epileptic spasms in a patient with 22q13.3 deletion syndrome, BRAIN & DEVELOPMENT, 38(1), 109-112, JAN 2016
  10. A Patient with CTLA-4 Haploinsufficiency Presenting Gastric Cancer, JOURNAL OF CLINICAL IMMUNOLOGY, 36(1), 28-32, JAN 2016
  11. Cavernous angioma after chemotherapy for desmoplastic/nodular medulloblastoma associated with anhidrotic ectodermal dysplasia, CHILDS NERVOUS SYSTEM, 32(2), 395-398, FEB 2016
  12. Early eradication of factor VIII inhibitor in patients with congenital hemophilia a by immune tolrelance induction with a high dose of immunoglobulin, International Journal of Hematology
  13. Significance of ACADM mutations identified through newborn screening of MCAD deficiency in Japan, MOLECULAR GENETICS AND METABOLISM, 118(1), 9-14, MAY 2016
  14. Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype, BLOOD, 127(25), 3154-3164, JUN 23 2016
  15. Effective Treatment of a Childhood Blastic Plasmacytoid Dendritic Cell Neoplasm with a Cutaneous Tumor Alone by Stem Cell Transplantation with Reduced Intensity Conditioning, INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION, 32, S26-S31, JUN 2016
  16. Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4(+) T cells into distinct effector subsets, JOURNAL OF EXPERIMENTAL MEDICINE, 213(8), 1589-1608, JUL 25 2016
  17. IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice, JOURNAL OF IMMUNOLOGY, 197(8), 3008-3017, OCT 15 2016
  18. Screening of MCAD deficiency in Japan: 16 years' experience of enzymatic and genetic evaluation, MOLECULAR GENETICS AND METABOLISM, 119(4), 322-328, DEC 2016
  19. Phosphatase and tensin homolog (PTEN) mutation can cause activated phosphatidylinositol 3-kinase delta syndrome-like immunodeficiency, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 138(6), 1672-+, DEC 2016
  20. Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(51), E8277-E8285, DEC 20 2016
  21. Chronic mucocutaneous candidiasis disease associated with inborn errors of IL-17 immunity, CLINICAL & TRANSLATIONAL IMMUNOLOGY, 5, DEC 2016
  22. Early eradication of factor VIII inhibitor in patients with congenital hemophilia A by immune tolerance induction with a high dose of immunoglobulin, INTERNATIONAL JOURNAL OF HEMATOLOGY, 103(4), 473-477, APR 2016
  23. A 2-year-old Japanese girl with TNF receptor-associated periodic syndrome: A case report of the youngest diagnosed proband in Japan, MODERN RHEUMATOLOGY, 26(5), 798-801, 2016
  24. Increased interleukin-6 and high-sensitivity C-reactive protein levels in pediatric epilepsy patients with frequent, refractory generalized motor seizures, SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 25, 136-140, FEB 2015
  25. The International Immune Tolerance Induction Study and its follow-up study on Japanese hemophilia A patients with inhibitors, INTERNATIONAL JOURNAL OF HEMATOLOGY, 101(4), 362-368, APR 2015
  26. The postirradiation incidence of cavernous angioma is higher in patients with childhood pineoblastoma or primitive neuroectodermal tumors than medulloblastoma, CHILDS NERVOUS SYSTEM, 31(6), 901-907, JUN 2015
  27. STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function, JOURNAL OF EXPERIMENTAL MEDICINE, 212(6), 855-864, JUN 1 2015
  28. Mosaicism of an ELANE Mutation in an Asymptomatic Mother in a Familial Case of Cyclic Neutropenia, JOURNAL OF CLINICAL IMMUNOLOGY, 35(5), 512-516, JUL 2015
  29. IMMUNODEFICIENCIES Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations, SCIENCE, 349(6248), 606-613, AUG 7 2015
  30. Perceived Parenting Mediates Serotonin Transporter Gene (5-HTTLPR) and Neural System Function during Facial Recognition: A Pilot Study, PLOS ONE, 10(9), SEP 29 2015
  31. Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 136(4), 993-+, OCT 2015
  32. Remission of autoimmune neutropenia after development of Kawasaki disease, PEDIATRICS INTERNATIONAL, 57(5), 1012-1014, OCT 2015
  33. Paroxysmal nocturnal hemoglobinuria and telomere length predicts response to immunosuppressive therapy in pediatric aplastic anemia, HAEMATOLOGICA, 100(12), 1546-1552, NOV 2015
  34. Detection Of Mucor velutinosus in a Blood Culture After Autologous Periperal Blood Stem Cell Transplantation: A Pediatric Case Report, Medical Mycology Journal, 55(2), E43-8, 20140601
  35. Ictal Electroencephalography and Electromyography Features in Symptomatic Infantile Epileptic Encephalopathy with Late-Onset Spasms, NEUROPEDIATRICS, 45(1), 36-41, FEB 2014
  36. Simple diagnosis of STAT1 gain-of-function alleles in patients with chronic mucocutaneous candidiasis, JOURNAL OF LEUKOCYTE BIOLOGY, 95(4), 667-676, APR 2014
  37. Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis, HAEMATOLOGICA, 99(1), 19-27, JAN 2014
  38. A Pediatric Case of Peripheral Polyneuropathy With IgM anti-GM1 Antibody Associated With a Group A Beta-Hemolytic Streptococcus Infection, PEDIATRIC NEUROLOGY, 51(3), 441-443, SEP 2014
  39. Gene Alterations Involving the CRLF2-JAK Pathway and Recurrent Gene Deletions in Down Syndrome-Associated Acute Lymphoblastic Leukemia in Japan, GENES CHROMOSOMES & CANCER, 53(11), 902-910, NOV 2014
  40. Compound heterozygosity in GPR56 with bilateral frontoparietal polymicrogyria, BRAIN & DEVELOPMENT, 36(6), 528-531, JUN 2014
  41. Identification of the integrin beta 3 L718P mutation in a pedigree with autosomal dominant thrombocytopenia with anisocytosis, BRITISH JOURNAL OF HAEMATOLOGY, 160(4), 521-529, FEB 2013
  42. Central nervous system complications and neuroradiological findings in children with chronic active EpsteinBarr virus infection, PEDIATRICS INTERNATIONAL, 55(1), 72-78, FEB 2013
  43. Effects of idursulfase enzyme replacement therapy for Mucopolysaccharidosis type II when started in early infancy: Comparison in two siblings, MOLECULAR GENETICS AND METABOLISM, 108(3), 172-177, MAR 2013
  44. Acute severe encephalopathy related to human herpesvirus-6 infection in a patient with carnitine palmitoyltransferase 2 deficiency carrying thermolabile variants, BRAIN & DEVELOPMENT, 35(5), 449-453, MAY 2013
  45. Paroxysmal Periodic Dystonic Postures in an Infant with 18q23 Deletion Syndrome, NEUROPEDIATRICS, 44(3), 163-166, JUN 2013
  46. Heterozygosity for the Y701C STAT1 mutation in a multiplex kindred with multifocal osteomyelitis, HAEMATOLOGICA, 98(10), 1641-1649, OCT 2013
  47. Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia-derived pluipotent stem cells with heterozygous ELANE mutation, Proc Natl Acad Sci USA, 110, 3023-8, 20130601
  48. Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(8), 3023-3028, FEB 19 2013
  49. Reduced brain activation during imitation and observation of others in children with pervasive developmental disorder: a pilot study, BEHAVIORAL AND BRAIN FUNCTIONS, 9, MAY 29 2013
  50. Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T-cell memory formation and function, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 132(2), 400-+, AUG 2013
  51. Management of advanced-stage neuroblastoma in a patient with 21-hydroxalase deficiency, PEDIATRICS INTERNATIONAL, 55(4), E96-E99, AUG 2013
  52. Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells, JOURNAL OF EXPERIMENTAL MEDICINE, 210(12), 2739-2753, NOV 18 2013
  53. IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts, BLOOD, 122(24), 3940-3950, DEC 5 2013
  54. Transient pseudothrombocytopenia in a neonate: Transmission of a maternal EDTA-dependent anticoagulant, PLATELETS, 23(5), 399-400, 2012
  55. Frequent somatic mosaicism of NEMO in T cells of patients with X-linked anhidrotic ectodermal dysplasia with immunodeficiency, BLOOD, 119(23), 5458-5466, JUN 7 2012
  56. Dominant-negative STAT1 SH2 domain mutations in unrelated patients with mendelian susceptibility to mycobacterial disease, HUMAN MUTATION, 33(9), 1377-1387, SEP 2012
  57. Regulation of hematopoietic stem cells using protein transduction domain-fused Polycomb, EXPERIMENTAL HEMATOLOGY, 40(9), 751-760, SEP 2012
  58. Regulation of hematopoietic stem cells using protein transduction domain-fused Polycomb, EXPERIMENTAL HEMATOLOGY, 40(9), 751-760, SEP 2012
  59. Oncogenic fusion E2A-HLF sensitizes t(17;19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors, LEUKEMIA, 26(12), 2483-2493, DEC 2012
  60. Continuous intravenous infusion of ketamine and lidocaine as adjuvant analgesics in a 5-year-old patient with neuropathic cancer pain, Journal of Palliative Medicine, 15, 345-348, 20120801
  61. Evaluation of cerebellar mutism by arterial spin-labeling perfusion magnetic resonance imaging in a patient with atypical teratoid/rhabdoid tumor (AT/RT): a case report, CHILDS NERVOUS SYSTEM, 28(8), 1257-1260, AUG 2012
  62. Endocrine complications in primary immunodeficiency diseases in Japan, CLINICAL ENDOCRINOLOGY, 77(4), 628-634, OCT 2012
  63. Decreased expression in nuclear factor-kB essential modulator due to a novel splice-site mutation causes X-linked ectodermal dysplasia with immunodeficiency., Journal of Clinical Immunology, 31(5), 762-772, 20111001
  64. Clinical and host genetic characteristics of Mendelian susceptibility to mycobacterial diseases in Japan, Journal of Clinical Immunology, 31, 309-314, 20110301
  65. Quantification of k-deleting recombination excision in Guthrie cards for identification of early B-cell maturation defects, Journal of Allergy & Clinical Immunology, 128, 223-225, 20110301
  66. Gain of function of human STAT1 mutations impair IL17 immunity and underlie chronic mucocutaneous candidiasis, J Exp Med., 208, 1635-48, 20110701
  67. Decreased expression in nuclear factor-B essential modulator due to a novel-site mutation causes X-linked ectordermal dysplasia with immunodeficiency, J Clin Immunol, 31, 762-772, 20110701
  68. Risk stratification for advanced neuroblastomas to identify of therapy-sensitive and therapy-resistant subtypes, Cancer Letter, 306, 27-33, 20110701
  69. Nation-wide survey of patients with primary immunodeficiency diseases in Japan, Journal of Clinical Immunology, 31, 968-976, 20111001
  70. A case of neonatal coxsackie B2 meningo-encephalitis in which serial magnetic response imaging findings reveal the developmental of lesions, Neuropediatrics, 42, 156-8, 20110501
  71. Association of viral isolates from stool samples with intussusception in children, International Journal of Infectious diseases, 15, 641-645, 20111001
  72. Identification of therapy-sensitive and therapy-resistant neuroblastoma subtypes in stages III, IVs and IV, CANCER LETTERS, 306(1), 27-33, JUL 1 2011
  73. Clinical and Host Genetic Characteristics of Mendelian Susceptibility to Mycobacterial Diseases in Japan, JOURNAL OF CLINICAL IMMUNOLOGY, 31(3), 309-314, JUN 2011
  74. Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis, JOURNAL OF EXPERIMENTAL MEDICINE, 208(8), 1635-1648, AUG 1 2011
  75. Association of viral isolates from stool samples with intussusception in children, INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 15(9), E641-E645, SEP 2011
  76. A Case of Neonatal Coxsackie B2 Meningo-Encephalitis in which Serial Magnetic Resonance Imaging Findings Reveal the Development of Lesions, NEUROPEDIATRICS, 42(4), 156-158, AUG 2011
  77. Decreased Expression in Nuclear Factor-kappa B Essential Modulator Due to a Novel Splice-Site Mutation Causes X-linked Ectodermal Dysplasia with Immunodeficiency, JOURNAL OF CLINICAL IMMUNOLOGY, 31(5), 762-772, OCT 2011
  78. Nationwide Survey of Patients with Primary Immunodeficiency Diseases in Japan, JOURNAL OF CLINICAL IMMUNOLOGY, 31(6), 968-976, DEC 2011
  79. Population pharmacokinetics and pharmacodynamics of meropenem in Japanese pediatric patients, JOURNAL OF INFECTION AND CHEMOTHERAPY, 16(2), 139-143, APR 2010
  80. A case of frontal lobe epilepsy in which amplitude-integrated EEG combined with conventional EEG was useful for evaluating clusters of seizures, EPILEPSY & BEHAVIOR, 18(4), 485-487, AUG 2010
  81. Maternal breast milk odour induces frontal lobe activation in neonates: A NIRS study, EARLY HUMAN DEVELOPMENT, 86(9), 541-545, SEP 2010
  82. Hepatic arterial infusion of liposomal amphotericin B for multiple fungal abscesses in the liver of a patient with chronic granulomatous disease, 51(5), 345, 20100501
  83. Significance of immature platelet fraction and CD41-positive cells at birth in early onset neonatal thrombocytopenia., Int J Hematol., 91(2), 245-51, 20100301
  84. Molecular pathogenesis of a novel mutation, G108D, in short-chain acyl-CoA dehydrogenase identified in subjects with short-chain acyl-CoA dehydrogenase deficiency, Human Genetics, 127(6), 619-628, 20100601
  85. Molecular pathogenesis of a novel mutation, G108D, in short-chain acyl-CoA dehydrogenase identified in subjects with short-chain acyl-CoA dehydrogenase deficiency., 127(6), 619-628, 20100601
  86. Significance of immature platelet fraction and CD-41-positive cells at birth in early onset neonatal thrombocytopenia., 91, 245-251, 20100401
  87. Maternal breast milk odour induces frontal lobe activation in neonates: A NIRS study., Early Human Development, 86(9), 541-545, 20100901
  88. Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential., Proc. Natl. Acad. Sci. USA, 107(50), 21529-21534, 20101201
  89. Molecular pathogenesis of a novel mutation, G108D, in short-chain acyl-CoA dehydrogenase identified in subjects with short-chain acyl-CoA dehydrogenase deficiency, Human Genetics 2010 Jun, 127(6), 619-28, 20100601
  90. Significance of immature platelet fraction and CD-41-positive cells at birth in early onset neonatal thrombocytopenia, International Journal of Hematology, 91, 245-251, 20100701
  91. Association of viral isolates from stool samples with intussusception in children, An analysis of a single hospital in Hiroshima, Japan, 20100901
  92. Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential, Proc. Natl. Acad. Sci. USA, 107(50), 21529-34, 20101001
  93. Hematological malignancies in congenital neutropenia, Rinsho Ketsueki, 51, 553-558, 20101001
  94. Significance of immature platelet fraction and CD41-positive cells at birth in early onset neonatal thrombocytopenia, INTERNATIONAL JOURNAL OF HEMATOLOGY, 91(2), 245-251, MAR 2010
  95. Molecular pathogenesis of a novel mutation, G108D, in short-chain acyl-CoA dehydrogenase identified in subjects with short-chain acyl-CoA dehydrogenase deficiency, HUMAN GENETICS, 127(6), 619-628, JUN 2010
  96. Recurrent acute cerebellar ataxia associated with anti-cardiolipin antibodies, BRAIN & DEVELOPMENT, 32(7), 588-591, AUG 2010
  97. Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(50), 21529-21534, DEC 14 2010
  98. Reciprocal expression of Bmi1 and Mel-18 is associated with the function of primitive hematopoietic cells., Exp Hematol, 37, 857-866, 20090503
  99. Spinal Epidural Granulocytic Sarcoma in a Child Precedent to Clinical Manifestation of Acute Myeloid Lymphoma, Neurologia medico-chirugica (Tokyo), 49(5), 221-224, 20090501
  100. Successful treatment of Kasabach-Merritt syndrome with vincristine and diagnosis of the hemangioma using three-dimensional imaging., Pediatric Hematology and Oncology, 26(5), 375-80, 20090701
  101. Respiratory complications after haematopoietic stem cell transplantation in a patient with chronic granulomatous disease., Transfusion Medicine, 19(2), 105-8, 20090401
  102. Short-Term Culture of Umbilical Cord Blood-Derived CD34 Cells Enhances Engraftment into NOD/SCID Mice Through Increased CXCR4 Expression., Stem Cells Develop, 18(8), 1221-1226, 20091001
  103. Cardiac infiltration in early-onset sarcoidosis associated with a novel heterozygous mutation, G481D, in CARD15., Rheumatology (Oxford), 48(6), 706-707, 20090601
  104. Deficiency of regulatory T cells in children with autoimmune neutropenia, British Journal of Haematology., 145, 642-647, 20090101
  105. Short-term culture of umbilical cord blood-derived CD34+ cells enhances the engraftment into NOD/SCID mice through the increased expression of CXCR4, Stem Cells & Developments, 18, 1221-6, 20090201
  106. Successful bone marrow transplantation in a patient with chronic granulomatous disease complicated by serious infections using nonmyeloablative conditioning, Pediatrics International, 51, 838-841, 20090301
  107. Respiratory complications after haematopoietic stem cell transplantation in a patient with chronic granulomatous disease, Transfusion Medicine, 19, 105-108, 20090301
  108. Cardiac infiltration in Early-Onset Sarcoidosis Associated with a Novel Heterozygous Mutation, G481D, in CARD15, Rheumatology, 48, 706-7, 20090401
  109. Different neuroradiological findings during two stroke-like episodes in a patient with a congenital disorder of glycosilation type Ia, Brain & Development, 31, 240-243, 20090501
  110. Successful treatment of Kasabach-Merritt syndrome diagnosed by three-dimensional computed tomography with vincristine, Pediatric Hematology & Oncology, 26, 375-380, 20090701
  111. Reciprocal expression of Bmi1 and Mel-18 is associated with the functioning of primitive hematopoietic cells, Experimental Hematology, 37, 857-866, 20090701
  112. Ela2 mutations and clinical manifestations in familial congenital neutropenia, Journal of Pediatric Hematology Oncology, 31, 319-324, 20090901
  113. Spinal epidural granulocytic sarcoma in a child precedent to clinical manifestation of acute myeloid lymphoma, Neurol Med Chir (Tokyo), 49, 221-224, 20091001
  114. Successful treatment of Kasabach-Merritt syndrome diagnosed by three-dimensional computed tomography with vincristine, Pediatric Hematology & Oncology, 26, 375-380, 20091001
  115. Dosing regimen rationalization of biapenem in pediatric patients: Use of Monte Carlo simulation, Japanese Journal of Antibiotics, 62, 1-8, 20091201
  116. A case of polyovular twins with neonatal alloimmune neutropenia associated with maternal anti-HNA-1b antibody, Pediatrics International, 49, 530-532, 20091201
  117. SUCCESSFUL TREATMENT OF KASABACH-MERRITT SYNDROME WITH VINCRISTINE AND DIAGNOSIS OF THE HEMANGIOMA USING THREE-DIMENSIONAL IMAGING, PEDIATRIC HEMATOLOGY AND ONCOLOGY, 26(5), 375-380, 2009
  118. Different neuroradiological findings during two stroke-like episodes in a patient with a congenital disorder of glycosylation type Ia, BRAIN & DEVELOPMENT, 31(3), 240-243, MAR 2009
  119. Dizygotic twins with neonatal alloimmune neutropenia associated with maternal anti-human neutrophil antigen-1b antibody, PEDIATRICS INTERNATIONAL, 51(2), 298-299, APR 2009
  120. Epileptic Spasms After Stem Cell Transplantation for Chronic Epstein-Barr Virus Infection, PEDIATRIC NEUROLOGY, 40(5), 404-407, MAY 2009
  121. Ela2 Mutations and Clinical Manifestations in Familial Congenital Neutropenia, JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 31(5), 319-324, MAY 2009
  122. Deficiency of regulatory T cells in children with autoimmune neutropenia, BRITISH JOURNAL OF HAEMATOLOGY, 145(5), 642-647, JUN 2009
  123. Current Situation of Drug Information in the Kindergarten and Nursery Teacher: A Pilot Study, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 129(5), 617-622, MAY 2009
  124. Spinal Epidural Granulocytic Sarcoma in a Child Precedent to Clinical Manifestation of Acute Myeloid Lymphoma -Case Report-, NEUROLOGIA MEDICO-CHIRURGICA, 49(5), 221-224, MAY 2009
  125. Reciprocal expression of Bmi1 and Mel-18 is associated with functioning of primitive hematopoietic cells, EXPERIMENTAL HEMATOLOGY, 37(7), 857-866, JUL 2009
  126. Short-Term Culture of Umbilical Cord Blood-Derived CD34 Cells Enhances Engraftment Into NOD/SCID Mice Through Increased CXCR4 Expression, STEM CELLS AND DEVELOPMENT, 18(8), 1221-1226, OCT 2009
  127. Successful bone marrow transplantation in chronic granulomatous disease, PEDIATRICS INTERNATIONAL, 51(6), 838-841, DEC 2009
  128. Population pharmacokinetics and pharmacodynamics of biapenem in paediatric patients, JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 33(2), 203-210, APR 2008
  129. Neurodevelopmental abnormalities associated with severe congenital neutropenia due to the R86X mutation in the HAX1 gene., J. Med. Genet., 45(12), 802-807, 20081201
  130. Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity., Proc. Natl. Acad. Sci. USA, 105(30), 10396-10401, 20080729
  131. Development of a new enzymatic diagnosis method for very-long-chain acyl-CoA dehydrogenase deficiency by detecting 2-hexadecenoyl-CoA production and its application in tandem mass spectrometry-based selective screening and newborn screening in Japan., Pediatric Research, 64(6), 667-672, 20081201
  132. The mobility of Bach2 nuclear foci is regulated by SUMO-1 modification, Experimental Cell Research, 314(4), 903-13, 20080401
  133. Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity, Proc. Natl. Acad. Sci. USA, 105(30), 10396-401, 20080701
  134. Neurodevelopmental abnormalities associated with severe congenital neutropenia due to the R86X mutation in the HAX1 gene, Journal of Medical Genetics, 45(12), 802-7, 20081001
  135. Development of a new enzymatic diagnosis method for very-long-chain acyl-CoA dehydrogenase deficiency by detecting 2-hexadecenoyl-CoA production and its application in tandem mass spectrometry-based selective screening and newborn screening in Japan, Pediatric Research, 64, 667-672, 20081201
  136. The mobility of Bach2 nuclear foci is regulated by SUMO-1 modification, EXPERIMENTAL CELL RESEARCH, 314(4), 903-913, FEB 15 2008
  137. Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(30), 10396-10401, JUL 29 2008
  138. Development of a New Enzymatic Diagnosis Method for Very-long-chain Acyl-CoA Dehydrogenase Deficiency by Detecting 2-Hexadecenoyl-CoA Production and its Application in Tandem Mass Spectrometry-based Selective Screening and Newborn Screening in Japan, PEDIATRIC RESEARCH, 64(6), 667-672, DEC 2008
  139. Neurodevelopmental abnormalities associated with severe congenital neutropenia due to the R86X mutation in the HAX1 gene, JOURNAL OF MEDICAL GENETICS, 45(12), 802-807, DEC 2008
  140. Steroid-dependent ACTH-produced thymic carcinoid: Regulation of POMC gene expression by cortisol via methylation of its promoter region, HORMONE RESEARCH, 67(5), 257-262, 2007
  141. High-performance liquid chromatography with ultraviolet detection for real-time therapeutic drug monitoring of meropenem in plasma, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 856(1-2), 371-375, SEP 1 2007
  142. A novel mutation (Gln433Glu) in exon 12 combined with the G insertion in exon 13 causes severe factor XI deficiency in Japanese patients, Blood Coagulation and Fibrinolysis, 18, 519-523, 20071001
  143. The novel IFNGR1 mutation 774del4 produces a truncated form of interferon-gamma receptor 1 and has a dominant-negative effect on interferon-gamma signal transduction, J. Med. Genet., 44, 485-491, 20070801
  144. Nuclear positioning of the BACH2 gene in BCR-ABL positive leukemic cells., Genes Chromosomes Cancer., 46(1), 67-74, 20070101
  145. The novel IFNGR1 mutation 774del4 produces a truncated form of interferon-gamma receptor 1 and has a dominant-negative effect on interferon-gamma signal transduction., J Med Genet, 44(8), 485-491, 20070801
  146. Floating culture promotes the maintenance of hematopoietic stem cells., FEBS Letter, 581(4645), 20070901
  147. Severe developmental delay and epilepsy in a Japanese patient with severe congenital neutropenia due to HAX1 deficiency, Haematologica, 92, 20071201
  148. Floating culture promotes the maintenance of hematopoietic stem cells., FEBS Letters, 581, 4645-50, 20070901
  149. The novel IFNGR1 mutation 774del4 produces a truncated form of interferon-g4567910 receptor 1 and has a dominant-negative effect on interferon-? signal transduction, Journal of Human Genetics, 44, 485-491, 20070601
  150. Developmental changes of aldehyde oxidase activity in young Japanese children, Clinical Pharmacology & therapeutics, 81, 567-572, 20070601
  151. High-performance liquid chromatography with ultraviolet detection for real-time therapeutic drug monitoring of meropenem in plasma, Journal of Chromatography B, 856, 371-375, 20070201
  152. Steroid-dependent ACTH-produced thymic carcinoid: regulation of the POMC gene expression by cortisol via methylation of its promoter region., Hormone research, 67, 257-262, 20070201
  153. Dynamics and induction of the BACH2 gene by imatinib mesylate in chronic myeloid leukemia cells, Genes Chromosomes and Cancer, 46, 67-74, 20070110
  154. Frontal cerebral blood flow change associated with infant-directed speech (IDS), Archives of Disease in Childhood (Fetal Neonatal Edition), 92, F113-116, 20070401
  155. The function of the frontal lobe in neonates for response to a prosodic voice, Early Human Development, 83, 225-230, 20070201
  156. A nobel mutation (Gln433Glu) in exon 12 combined with the G insertion in exon 13 causes severe factor XI deficiency in Japanese patients., Blood Coagulation Fibrinolysis, 18(5), 519-523, 20070501
  157. Successful treatment with liposteroid followed by reduced intensity stem cell transplantation in an infant with perforin deficiency presenting with hemophagocytic lymphohistiocytosis., Journal of Pediatric Hematology/Oncology, 29, 178-182, 20070301
  158. Dynamics and induction of the BACH2 gene by imatinib mesylate in chronic myeloid leukemia cells, Genes Chromosomes and Cancer 2007, 46, 67-74, 20070301
  159. The function of the frontal lobe in neonates for response to a prosodic voice, Early Human Development 2007, 83, 225-230, 20070701
  160. Frontal cerebral blood flow change associated with infant-directed speech (IDS), Archives of Disease in Childhood (Fetal Neonatal Edition) 2007, 92, F113-116, 20070501
  161. Steroid-dependent ACTH-produced thymic carcinoid: regulation of the POMC gene expression by cortisol via methylation of its promoter region, Hormone Research 2007, 67, 257-262, 20070601
  162. Successful treatment with liposteroid followed by reduced intensity stem cell transplantation in an infant with perforin deficiency presenting with hemophagocytic lymphohistiocytosis, Journal of Pediatric Hematology & Oncology, 29, 178-182, 20070901
  163. A novel mutation (Gln433Glu) in exon 12 combined with the G insertion in exon 13 causes severe factor XI deficiency in Japanese patients, Blood coagulation & Fibrinolysis 2007, 18, 519-523, 20071001
  164. The novel IFNGR1 mutation 774del4 produces a truncated form of interferon-g receptor 1 and has a dominant-negative effect on interferon-g signal transduction, Journal of Medical Genetics, 2007, 44, 485-491, 20071001
  165. Severe developmental delay and epilepsy in a Japanese patient with severe congenital neutropenia due to HAX1 deficiency, Haematologica 2007, 92, e123-125, 20071101
  166. Floating culture promotes the maintenance of hematopoietic stem cells, FEBS Letters 2007, 581, 4645-50, 20071101
  167. High-performance liquid chromatography with ultraviolet detection for real-time therapeutic drug monitoring of meropenem in plasma, Journal of Chromatography B 2007, 856, 371-375, 20071201
  168. Developmental changes of aldehyde oxidase activity in young Japanese children, Clinical Pharmacology & Therapeutics 2007, 81, 567-572, 20071201
  169. Nuclear positioning of the BACH2 gene in BCR-ABL positive leukemic cells, GENES CHROMOSOMES & CANCER, 46(1), 67-74, JAN 2007
  170. Frontal cerebral blood flow change associated with infant-directed speech, ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 92(2), F113-F116, MAR 2007
  171. Successful treatment with liposteroid followed by reduced intensity stem cell transplantation in an infant with perforin deficiency presenting with hemophagocytic lymphohistiocytosis, JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 29(3), 178-182, MAR 2007
  172. The function of the frontal lobe in neonates for response to a prosodic voice, EARLY HUMAN DEVELOPMENT, 83(4), 225-230, APR 2007
  173. A novel mutation (Gln433Glu) in exon 12 combined with the G insertion in exon 13 causes severe factor XI deficiency in Japanese patients, BLOOD COAGULATION & FIBRINOLYSIS, 18(5), 519-523, JUL 2007
  174. The novel IFNGR1 mutation 774del4 produces a truncated form of interferon-gamma receptor 1 and has a dominant-negative effect on interferon-gamma signal transduction, JOURNAL OF MEDICAL GENETICS, 44(8), 485-491, AUG 2007
  175. Floating culture promotes the maintenance of hematopoietic stem cells, FEBS LETTERS, 581(24), 4645-4650, OCT 2 2007
  176. Detection of autoantibodies against NMDA-type glutamate receptor in a patient with recurrent optic neuritis and transient cerebral lesions, NEUROPEDIATRICS, 38(5), 257-260, OCT 2007
  177. Moyamoya Syndrome after Cranial Irradiation for Bone Marrow Transplantation in a Patient with Acute Leukemia, Neuropediatrics, 37, 364-366, 20061201
  178. Autoimmune neutropenia of infancy with multiple brain abscesses during the course of human herpesvirus-6 infection, International Journal of Hematology, 84, 151-153, 20060601
  179. Effect of green tea beverages on efficacy of providone-iodine, Journal of Health Science, 52(3), 324-328, 20061101
  180. Autoimmune neutropenia of infancy with multiple brain abscesses during the course of human herpesvirus-6 infection., International Journal of Hematology, 84, 151-153, 20060701
  181. Effect of green tea beverages on efficacy of providone-iodine, Journal of Health Science, 52(3), 324-328, 20060501
  182. Autoimmune neutropenia of infancy with multiple brain abscesses during the course of human herpesvirus-6 infection, International Journal of Hematology, 84, 151-153, 20060601
  183. Moyamoya Syndrome after Cranial Irradiation for Bone Marrow Transplantation in a Patient with Acute Leukemia, Neuropediatrics, 37, 364-6, 20060801
  184. Effect of green tea beverages on efficacy of povidone-iodine, JOURNAL OF HEALTH SCIENCE, 52(3), 324-328, JUN 2006
  185. Autoimmune neutropenia of infancy with multiple brain abscesses during the course of human herpesvirus-6 infection, INTERNATIONAL JOURNAL OF HEMATOLOGY, 84(2), 151-153, AUG 2006
  186. Moyamoya syndrome after cranial irradiation for bone marrow transplantation in a patient with acute leukemia, NEUROPEDIATRICS, 37(6), 364-366, DEC 2006
  187. A comparison of the defective granulopoiesis in childhood cyclic neutropenia and in severe congenital neutropenia., Haematologica, 90, 1032-41, 20050401
  188. Enzymatic diagnosis of medium-chain acyl-CoA dehydrogenase deficiency by detecting 2-octenoyl-CoA production using high-performance liquid chromatography: a practical confirmatory test for tandem mass spectrometry newborn screening in Japan., Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 823(2), 122-130, 20050901
  189. Establishment of a practical enzymatic assay method for determination of isovaleryl-CoA dehydrogenase activity using high-performance liquid chromatography., Clinica Chimica Acta, 353(1-2), 193-199, 20050301
  190. A case of adolescent primary adrenal natural killer cell lymphoma, International Journal of Hematology, 81, 330-334, 20051101
  191. A comparison of the defective granulopoiesis in childhood cyclic neutropenia and in severe congenital neutropenia., Haematologica, 90(8), 1032-1041, 20050801
  192. A comparison of defective granulopoiesis in childhood cyclic neutropenia and severe congenital neutropenia., Haematologica, 90(8), 1032-1041, 20050801
  193. Establishment of a practical enzymatic assay method for determination of isovaleryl-CoA dehydrogenase activity using high-performance liquid chromatography, Clinica Chimica Acta, 353, 193-199, 20050701
  194. A comparison of the defective granulopoiesis in childhood cyclic neutropenia and in severe congenital neutropenia, Haematologica, 90, 1032-1041, 20050901
  195. Enzymatic diagnosis of medium-chain acyl-CoA dehydrogenase deficiency by detecting 2-octenoyl-CoA production using high-performance liquid chromatography: a practical confirmatory test for tandem mass spectrometry newborn screening in Japan, Journal of Chromatography B - Analytical Technologies in the biomedical and Life Sciences, 823, 122-130, 20051001
  196. A case of adolescent primary adrenal natural killer cell lymphoma, International Journal of Hematology, 81, 330-334, 20051001
  197. Establishment of a practical enzymatic assay method for determination of isovaleryl-CoA dehydrogenase activity using high-performance liquid chromatography, CLINICA CHIMICA ACTA, 353(1-2), 193-199, MAR 2005
  198. A case of adolescent primary adrenal natural killer cell lymphoma, INTERNATIONAL JOURNAL OF HEMATOLOGY, 81(4), 330-334, MAY 2005
  199. Enzymatic diagnosis of medium-chain acyl-CoA dehydrogenase deficiency by detecting 2-octenoyl-CoA production using high-performance liquid chromatography: A practical confirmatory test for tandem mass spectrometry newborn screening in Japan, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 823(2), 122-130, SEP 5 2005
  200. A comparison of the defective granulopoiesis in childhood cyclic neutropenia and in severe congenital neutropenia, HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 90(8), 1032-1041, AUG 2005
  201. Significance of human neutrophil antigen-2a (NB1) expression and neutrophil number in pregnancy, Transfusion, 44, 581-585, 20041001
  202. Significance of human neutrophil antigen-2a (NB1) expression and neutrophil number in pregnancy, TRANSFUSION, 44(4), 581-585, APR 2004
  203. Dysregulation of transcriptions in primary granule constituents during myeloid proliferation and differentiation in patients with severe congenital neutropenia., Journal of Leukocyte Biology, 73, 225-234, 20030401
  204. Efficacy of the prophylactic use of trimethoprim-sulfamethoxazole in auotimmune neutropenia in infancy., 25, 553-557, 20030401
  205. Dysregulation of transcriptions in primary granule constituents during myeloid proliferation and differentiation in patients with severe congenital neutropenia, Journal of Leukocyte Biology, 73, 225-234, 20030401
  206. Study on the Stress in Hospitalized Children with Hemato-Oncological Diseases : I. The Significance of Identification of Stressors, 17, 111-116, 20030401
  207. Efficacy of the prophylactic use of trimethoprim-sulfamethoxazole in auotimmune neutropenia in infancy, 25, 553-557, 20030401
  208. Dysregulation of transcripts in primary granule constituents during myeloid proliferation and differentiation in patents with severe congenital neutropenia., Journal of Leukocyte Biology, 73(2), 225-234, 20030401
  209. Efficacy of prophylactic use of Trimethoprim-Sulfametoxazole in autoimmune neutropenia in infancy., Pediatric Hematology and Oncology, 25(7), 553-557, 20030401
  210. Dysregulation of transcripts in primary granule constituents during myeloid proliferation and differentiation in patients with severe congenital neutropenia., Journal of Leukocyte Biology, 73(2), 225-234, 20030201
  211. Efficacy of prophylactic use of trimethoprim-sulfametoxazole in autoimmune neutropenia in infancy., Journal of Pediatric Hematology/Oncology, 25(7), 553-557, 20030701
  212. Dysregulation of transcriptions in primary granule constituents during myeloid proliferation and differentiation in patients with severe congenital neutropenia, Journal of Leukocyte Biology, 73, 225-234, 20030501
  213. Efficacy of the prophylactic use of trimethoprim-sulfamethoxazole in auotimmune neutropenia in infancy, Journal of Pediatric Hematology & Oncology, 25, 553-557, 20031001
  214. Dysregulation of transcriptions in primary granule constituents, during myeloid proliferation and differentiation in patients with severe congenital neutropenia, JOURNAL OF LEUKOCYTE BIOLOGY, 73(2), 225-234, FEB 2003
  215. Efficacy of prophylactic use of trimethoprim-sulfamethoxazole in autoimmune neutropenia in infancy, JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 25(7), 553-557, JUL 2003
  216. Human neutrophil antigen-2a expression of neutrophils from healthy adults in western Japan., Transfusion, 42, 651-657, 20020401
  217. Significance of the detection of antineutrophil antibodies in children with chronic neutropenia., Blood, 99, 3468-3471, 20020401
  218. Defects of granulopoiesis in patients with severe congenital neutropenia, Hiroshima Journal of Medical Sciences, 51, 63-74, 20020401
  219. Significance of the detection of antineutrophil antibodies in children with chronic neutropenia, Blood, 99, 3468-3471, 20020401
  220. Defects of granulopoiesis in patients with severe congenital neutropenia., Hiroshima J. Med. Sci., 51(3), 63-74, 20020301
  221. Significance of the detection of antineutrophil antibodies in children with chronic neutropenia., Blood, 99(9), 3468-3471, 20020401
  222. Defects of granulopoiesis in patients with severe congenital neutropenia, Hiroshima Journal of Medical Sciences, 51(3), 63-74, 20020401
  223. Defects of granulopoiesis with severe congenital neutropenia., Hiroshima Journal of Medical Science, 51(3), 63-74, 20020301
  224. Significance of the detection of antineutrophil antibodies in children with chronic neutropenia., Blood, 99(9), 3468-3471, 20020901
  225. Significance of the detection of antineutrophil antibodies in children with chronic neutropenia, Blood, 99, 3468-3471, 20020701
  226. Human neutrophil antigen-2a expression of neutrophils from healthy adults in western Japan, Transfusion, 42, 651-657, 20020901
  227. Defects of granulopoiesis in patients with severe congenital neutropenia, Hiroshima Journal of Medical Sciences, 51, 63-74, 20021001
  228. Significance of the detection of antineutrophil antibodies in children with chronic neutropenia, BLOOD, 99(9), 3468-3471, MAY 1 2002
  229. Human neutrophil antigen-2a expression on neutrophils from healthy adults in western Japan, TRANSFUSION, 42(5), 651-657, MAY 2002
  230. Clinical periodontal findings and microflora profiles in children with chronic neutropenia under supervised oral hygiene., Journal of Periodontology, 72, 945-952, 20010401
  231. A Possible Role of The Maternal Anti-HLA antibody in A Case of Alloimmune Neonatal Neutropenia., Transfusion, 41, 615-620, 20010401
  232. A possible role of the maternal anti-HLA antibody in a case of alloimmune neonatal neutropenia, Transfusion, 41, 615-620, 20010501
  233. Clinical periodontal findings and microflora profiles in children with chronic neutropenia under supervised oral hygiene, Journal of Periodontology, 72, 945-952, 20010601
  234. A possible role for maternal HLA antibody in a case of alloimmune neonatal neutropenia, TRANSFUSION, 41(5), 615-620, MAY 2001
  235. Abnormalities of Primitive Myeloid Progenitor Cells Expressing Granulocyte Colony-stimulating Factor Receptor in Patients with Severe Congenital Neutropenia, Blood, 96, 4366-4369, 20000401
  236. Thrombopoietin enhances neutrophil production by bone marrow hematopoietic progenitors with the aid of stem cell factor in congenital neutropenia., Journal of Leukocyte Biology, 68, 137-143, 20000401
  237. Insulin and Insulin-like Growth Factor-I Support the Proliferation of Erythroid Progenitor Cells in Bone Marrow through The Sharing of Receptors., British Journal of Haematology, 109, 555-562, 20000401
  238. Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs byinducing MCL1 acting as an anti-apoptotic factor., Cancer Research, 58, 5565-5569, 20000401
  239. Abnormalities of primitive myeloid progenitor cells expresssing granulocyte colony-stimulating factor receptor in patients with severe congenital neutropenia, Blood, 96, 4366-4369, 20000401
  240. Insulin and insulin-like growth factor I support the proliferation of erythroid progenitor cells in bone marrow through the sharing of receptors., British Journal of Haematology, 109, 555-562, 20000401
  241. Abormalities of primitive myeloid progenitor cells expressing granulocyte colony-stimulating factor receptor in patients with severe congenital neutropenia., Blood, 96(13), 4366-4369, 20000801
  242. ZK7, a novel zinc finger gene, is induced by vascular endothelial growth factor and inhibits apoptotic death in hematopoietic cells, Cancer Research, 60, 425-430, 20000301
  243. Insulin and insulin-like growth factor-I support the proliferation of erythroid progenitor cells in bone marrow through the sharing of receptors, British Journal of Haematology, 109, 555-562, 20000501
  244. Thrombopoietin enhances neutrophil production by bone marrow hematopoietic progenitors with the aid of stem cell factor in congenital neutropenia, Journal of Leukocyte Biology, 68, 137-143, 20000601
  245. Abnormalities of primitive myeloid progenitor cells expressing granulocyte colony-stimulating factor receptor in patients with severe congenital neutropenia, Blood, 96, 4366-4369, 20000501
  246. ZK7, a novel zinc finger gene is induced by vascular endothelial growth factor and inhibits apoptotic death in hematopoietic cells, CANCER RESEARCH, 60(2), 425-430, JAN 15 2000
  247. Insulin and insulin-like growth factor I support the proliferation of erythroid progenitor cells in bone marrow through the sharing of receptors, BRITISH JOURNAL OF HAEMATOLOGY, 109(3), 555-562, JUN 2000
  248. Abnormalities of primitive myeloid progenitor cells expressing granulocyte colony-stimulating factor receptor in patients with severe congenital neutropenia, BLOOD, 96(13), 4366-4369, DEC 15 2000
  249. Defective proliferation of primitive myeloid progenitor cells in patients with severe congenital neutropenia., Blood, 94, 4077-4083, 19990401
  250. Treatment of infantile acute lymphoblastic leukemima in Japan., International Journal of Hematology, 69, 244-252, 19990401
  251. Serum granulocyte colony-stimulating factor levels in patients with chronic neutropenia of childhood: Modulation of G-CSF levels by myeloid precursor cell mass., British Journal of Haematology, 105, 486-490, 19990401
  252. Defective proliferation of myeloid progenitor cells in patients with severe congenital neutropenia., Blood, 94, 4077-4083, 19990401
  253. Serum granulocyte colony-stimulating factor levels in patients with chronic neutropenia of childhood: Modulation of G-CSF levels by myeloid precursor cell mass, British Journal of Haematology, 105, 486-490, 19990201
  254. Treatment of infantile acute lymphoblastic leukemima in Japan, International Journal of Hematology, 69, 244-252, 19990501
  255. Defective proliferation of primitive myeloid progenitor cells in patients with severe congenital neutropenia, Blood, 94, 4077-4083, 19991001
  256. ZK7, a Novel Zinc Finger Gene, Is Induced by Vascular Endothelial Growth Factor and Inhibits Apoptotic Death in Hematopoietic Cells., Cancer Research, 60, 425-430, 19980401
  257. Engraftment of cultured human hematopoietic cells in sheep., Blood, 91, 3688-3692, 19980401
  258. Poliovirus Type-specific Neutralizing Antibodies in Sera of University Students born in 1975 to 1977, 57, 684-688, 19980401
  259. Engraftment of cultured human hematopoietic cells in sheep, Blood, 91, 3688-3692, 19980801
  260. Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs byinducing MCL1 acting as an anti-apoptotic factor, Cancer Research, 58, 5565-5569, 19980501
  261. Thrombopoietin, steel factor and the ligand for flt3/flk2 interact to stimulate the proliferation of human hematopoietic progenitors in culture., International Journal of Hematology, 66, 423-434, 19970401
  262. Treatment outcome of AT-B88 regimen for B-cell non-Hodgkinユs lymphoma and surface immunoglobulin-positive acute lymphoblastic leukemia in children., International Journal of Hematology, 66, 89-98, 19970401
  263. Treatment outcome of AT-B88 regimen for B-cell non-Hodgkin's lymphoma and surface immunoglobulin-positive acute lymphoblastic leukemia in children, International Journal of Hematology, 66, 89-98, 19971001
  264. Thrombopoietin, steel factor and the ligand for flt3/flk2 interact to stimulate the proliferation of human hematopoietic progenitors in culture, International Journal of Hematology, 66, 423-434, 19970201
  265. Thrombopoietin supports proliferation of human Primitive hematopoietic cells in synergy with steel factor and/or interleukin-3, Blood, 88(2), 429-436, 19960401
  266. A monoclonal antibody, TAG-1, to neutrophil NA1 antigen., 152?152, 19960401
  267. Synergistic response of cord blood myeloid progenitor cells to the combined administration of human granulocyte colony-stimulating factor and human stem cell factor in vitro., Pediatric Research, 40, 338-392, 19960401
  268. Aberrant growth of granulocyte-macrophage progenitors in juvenile chronic myelogenous leukemia in serum-free culture., Experimental Hematology, 24, 116-122, 19960401
  269. Aberrant growth of granulocyte-macrophage progenitors in juvenile chronic myelogenous leukemia in serum-free culture, Experimental Hematology, 24, 116-122, 19960101
  270. Thrombopoietin supports proliferation of human primitive hematopoietic cells in synergy with steel factor and/or interleukin 3, Blood, 88, 429-436, 19961001
  271. Synergistic response of cord blood myeloid progenitor cells to the combined administration of human granulocyte colony-stimulating factor and human stem cell factor in vitro, Pediatric Research, 40, 338-392, 19960201
  272. The psychosocial factors facilitating partner notification and mutual coming-out in HIV/AIDS counseling. "jointly authored", Bulletin of General Health Research, 11, 29-40, 19950401
  273. Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors., Blood, 86, 2494-2499, 19950401
  274. Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors, Blood, 86, 2494-2499, 19951001
  275. The psycosocial factors fascilitating partner notification in cases of HIV infection., AIDS Research Newsletter (Proc. of 7th congress of Jap. Soc. for AIDS Res.), 7, 124?124, 19940401
  276. Genotypical classification of neutrophil Fcg receptor III by polymerase chain reaction-single-strand conformation polymorphism., Blood, 83, 3312-3315, 19940401
  277. Poor outcome in patients with advanced stage neuroblastoma and coincident opsomyoclonus syndrome., Cancer, 74, 1821-1826, 19940401
  278. Genotypical Classification of Neutrophil FcGamma Receptor III by Polymerase Chain Reaction-Single-Strand Conformation Polymorphism., Blood, 83(11), 3312-3315, 19941101
  279. Genotypical classification of neutrophil Fcg receptor III by polymerase chain reaction-single-strand conformation polymorphism, Blood, 83, 3312-3315, 19940401
  280. Poor outcome in patients with advanced stage neuroblastoma and coincident opsomyoclonus syndrome, Cancer, 74, 1821-1826, 19941101
  281. Recombinant human granulocyte colony stimulating factor in the treatment of patients with chronic benign neutropenia and congenital agranulocytosis (Kostmann's syndrome), Acta Paediatrica, 81, 133-136, 19920801
  282. Infants leukemia in Japan, Medical and Pediatric Oncology, 19, 28-32, 19910401
  283. Tumor necrosis factor in the cerebrospinal fluid of children with central nervous system leukemia., Leukemia Research, 15, 143-147, 19910401
  284. G-CSF, 27, 19910401
  285. Tumor necrosis factor in the cerebrospinal fluid of children with central nervous system leukemia, Leukemia Research, 15, 143-147, 19910101
  286. Infant leukemia in Japan: clinical and biological analysis of 48 cases, Medical and Pediatric Oncology, 19, 28-32, 19910101
  287. Abnormal responses of myeloid progenitor cells to recombinamt human colony-stimulatimy factors in conglnital neutropenia., Blood, 75(11), 2143-2149, 19900401
  288. Isolation and characterization of VP-16 resistant human leukemia cell line., 44, 35-40, 19900401
  289. Reduced DNA Aopoisonevate (]G0002[) in Vp-16 resistant mouye breast cacee cell line., Biomedicine and Pharmacotherapy, 44, 41-45, 19900401
  290. Isolation and characterization of VP-16 resistant human leukemia cell line, Biomedicine and Pharmacotherapy, 44, 35-40, 19900801
  291. Reduced DNA topoisomerase II in VP-16 resistant mouse breast cancer cell line, Biomedicine and Pharmacotherapy, 44, 41-45, 19900501
  292. Abnormal responses of myeloid progenitor cells to recombinant human colony-stimulating factors in congenital neutropenia., Blood, 75, 2143-2149, 19900401
  293. Autoimmune neutropenia in infancy due to anti-NA1 antibody: Detection of antibody with immunofluorescence and agglutination test., Pediatric Researeh, 26, 246-249, 19890401
  294. Leukotriene B4 metabolism in neutrophils of patients with chronic granulomatous disease: phorbol myristate acetate decreases endogenous leukotriene B4 via NADPH oxidase-dependent mechanism., European Journal of Clinical Investigation, 19, 404-411, 19890401
  295. Leukotriene B4 metabolism in neutrophils of patients with chronic granulomatous disease: phorbol myristate acetate decreases endogenous leukotirene B4 via NADPH oxidase-dependent mechanism, Eur.J.Clin.Invest, 19(8), 404-411, 19890801
  296. Autoimmune neutropenia in infancy due to anti-NA1 antibody: Detection of antibody with immunofluorescence and agglutination test., Pediatric Research, 26(3), 246-249, 19890301
  297. Leukotriene B4 metabolism in neutrophils of patients with chronic granulomatous disease: phorbol myristate acetate decreases endogenous leukotriene B4 via NADPH oxidase-dependent mechanism, European Journal of Clinical Investigation, 19, 404-411, 19891201
  298. Autoimmune neutropenia in infancy due to anti-NA1 antibody: Detection of antibody with immunofluorescence and agglutination test, Pediatric Research, 26, 246-249, 19891001
  299. Impaired production of leukotriene by peripheral blood polymorphonuclear leukocytes from patients with chronic renal disease., Clinica Chinica Acta, 173, 235-238, 19880401
  300. Impaired production of leukotrienes by peripheral blood polymorphonuclear leukocytes from children with chronic renal failure., Clin Chim Acta, 173(5), 235-238, 19880501
  301. Impaired production of leukotriene by peripheral blood polymorphonuclear leukocytes from patients with chronic renal disease, Clinica Chimica Acta, 173, 235-238, 19880501
  302. Asymmetric ventricular hypertrophy in I-cell disease, J Inher Metab Dis, 9(8), 401-402, 19860801
  303. Protein phosphorylation of neutrophils from normal children and patients with chronic granulomatous disease., European Journal of Pediatrics, 145, 22-26, 19860401
  304. Cytochemical investigation of skin window response in patients with chronic neutropenia., Acta Haematologica Japonica, 49, 54-60, 19860401
  305. Asymmetric ventricular septal hypertrophy in I-cell Disease., Journal of Inherited and Metabolic Disease, 9, 401-402, 19860401
  306. Protein phosphorylation of neutrophils from normal children and patients with chronic granulomatous disease, European Journal of Pediatrics, 145, 22-26, 19861101
  307. Cytochemical investigation of skin window response in patients with chronic neutropenia, Acta Haematologica Japonica, 49, 54-60, 19860801
  308. Asymmetric ventricular septal hypertrophy in I-cell Disease, Journal of Inherited and Metabolic Disease., 9, 401-402, 19861001
  309. Granulopoiesis in patients with congenital neutropenia., American Journal of Hematology, 20, 223-234, 19850401
  310. Granulopoiesis in patients with congenital neutropenia, American Journal of Hematology, 20, 223-234, 19851001
  311. Presumed BCG infection in a boy with chronic granulomatous disease, Clin.Pediatr., 23(9), 586-589, 19840901
  312. Complete deficiency of adenine phosphoribosyltransferase: A report of three cases and immunologic and phagocytic investigations., Pediatr.Res, 18(1), 30-34, 19840101
  313. Membrane potential changes in polymorphonuclear leukocytes of patients with chronic granulomatous disease., Hiroshima Journal of Medical Sciences, 33, 173-177, 19840401
  314. Complete deficiency of adenine phosphoribosyl transferase: a report of three cases and immunologic and phagocytic investigations., Pediatric Research, 18, 30-34, 19840401
  315. Presumed BCG infection in a boy with chronic granulomatous disease: a report of a case and a review of the literature., Clinical Pediatrics, 23, 586-589, 19840401
  316. Membrane potential changes in polymorphonuclear leukocytes of patients with chronic granulomatous disease, Hiroshima Journal of Medical Sciences, 33, 173-177, 19840901
  317. Complete deficiency of adenine phosphoribosyl transferase: a report of three cases and immunologic and phagocytic investigations, Pediatric Research, 18, 30-34, 19841001
  318. Presumed BCG infection in a boy with chronic granulomatous disease: a report of a case and a review of the literature, Clinical Pediatrics, 23, 586-589, 19840501
  319. Hexosaminidase isoenzyme profiles in leukemic cells., Clinica Chimica Acta, 128, 19-28, 19830401
  320. Isoenzyme profiles of a-mannosidase and b-galactosidase in leukemic cells., Hiroshima Journal of Medical Sciences, 32, 207-212, 19830401
  321. Levels of vitamine D metabolites in a case of acroosteolysis syndrome., Acta Paediatrica Scandinavica, 72, 617-620, 19830401
  322. Functional analysis of polymorphonuclear leukocytes in siblings of glucose-6-phosphate dehydrogenase deficiency., Hiroshima Journal of Medical Sciences, 32, 173-178, 19830401
  323. Age-related decline in lysosomal enzyme release from polymorphonuclear leukocytes after N-formyl-methionyl-leucyl-phenylalanine stimulation., Experimental Hematology, 11, 1005-1013, 19830401
  324. Granular enzyme release from polymorphonuclear leukocytes: effect of the respiratory burst on enzyme activity., Acta Haematologica Japonica, 46, 1477-1486, 19830401
  325. Chronic granulomatous disease., 15, 137-138, 19830401
  326. Chronic granulomatous disease., 15, 137-138, 19830401
  327. DiGeorge syndrome., 15, 200-201, 19830401
  328. Impotent neutrophil syndrome., 15, 356, 19830401
  329. Lazy leukocyte syndrome., 15, 400-401, 19830401
  330. Hexosaminidase isoenzyme profiles in leukemic cells, Clinica Chimica Acta, 128, 19-28, 19830401
  331. Isoenzyme profiles of a-mannosidase and b-galactosidase in leukemic cells, Hiroshima Journal of Medical Sciences, 32, 207-212, 19831001
  332. Levels of vitamine D metabolites in a case of acroosteolysis syndrome, Acta Paediatrica Scandinavica, 72, 617-620, 19831001
  333. Functional analysis of polymorphonuclear leukocytes in siblings of glucose-6-phosphate dehydrogenase deficiency, Hiroshima Journal of Medical Sciences, 32, 173-178, 19830501
  334. Age-related decline in lysosomal enzyme release from polymorphonuclear leukocytes after N-formyl-methionyl-leucyl-phenylalanine stimulation, Experimental Hematology, 11, 1005-1013, 19830601
  335. Granular enzyme release from polymorphonuclear leukocytes: effect of the respiratory burst on enzyme activity, Acta Haematologica Japonica, 46, 1477-1486, 19831001
  336. Inactivation of lysosomal enzymes by the respiratory burst of polymorphonuclear leukocytes: Possible involvement of myeloperoxidase-H2O2-halide system., Journal of Laboratory and Clinical medicine, 100, 896-907, 19820401
  337. Inactivation of lysosomal enzymes by the respiratory burst of polymorphonuclear leukocytes: Possible involvement of myeloperoxidase-H2O2-halide system, Journal of Laboratory and Clinical Medicine, 100, 896-907, 19820401
  338. Lysosomal enzyme release from polymorphonuclear leukocytes in patients with chronic granulomatous disease: The effect of hydrogen peroxide on released enzyme activities., Hiroshima Journal of Medical Sciences, 30, 339-344, 19810401
  339. Biochemical activities of lysosomal acid hydrolases in leukemic cells., Clinica Chimica Acta, 117, 121-131, 19810401
  340. Lysosomal enzyme release from polymorphonuclear leukocytes in patients with chronic granulomatous disease: The effect of hydrogen peroxide on released enzyme activities, Hiroshima Journal of Medical Sciences, 30, 339-344, 19811001
  341. Biochemical activities of lysosomal acid hydrolases in leukemic cells, Clinica Chimica Acta, 117, 121-131, 19810801
  342. Biochemical activities of lysosomal enzymes in leukemic cells: The characteristic alterations of the enzyme levels in childhood acute leukemia., Hiroshima Journal of Medical Sciences, 29, 125-132, 19800401
  343. The philadelphia chromosome-positive acute leukemia with lymphoblastic characteristics., Hiroshima Journal of Medical Sciences, 29, 87-92, 19800401
  344. Biochemical activities of lysosomal enzymes in leukemic cells: The characteristic alterations of the enzyme levels in childhood acute leukemia, Hiroshima Journal of Medical Sciences, 29, 125-132, 19801001
  345. The philadelphia chromosome-positive acute leukemia with lymphoblastic characteristics, Hiroshima Journal of Medical Sciences, 29, 87-92, 19801001
  346. I-cell disease: Nine lysosomal enzyme levels in lymphocytes and granulocytes., Hiroshima Journal of Medical Sciences, 28, 189-193, 19790401
  347. I-cell disease: Nine lysosomal enzyme levels in lymphocytes and granulocytes, Hiroshima Journal of Medical Sciences, 28, 189-193, 19790501

Publications such as books

  1. 1993/08, Acute Leukemia IV  Long-term follow-up of a pilot study of intermittent intensive continuation therapy (HL-3 protocol) for childhood acute lymphoblastic leukemia. pp. 201-207, Springer-Verlag, Berlin, Heiderberg, , 1993, 08

Invited Lecture, Oral Presentation, Poster Presentation

  1. Langerhans cell histiocytosis: Case presentation, Hiroshi Kawaguchi, Masao Kobayashi, 2016/12/15, Without Invitation

Awards

  1. 1996年06月, The Mitchell J. Rubin Junior Research Award of Medical University of South Carolina Children's Hospital., Medical University of South Carolina Children's Hospital

External Funds

Acceptance Results of Competitive Funds

  1. Practical Research for Innovative Cancer Control , 2016/04/01, 2017/03/31
  2. Research on Development of New Drugs , 2016/04/01, 2017/03/31
  3. Practical Research Project for Rare / Intractable Diseases , 2016/04/01, 2017/03/31
  4. Practical Research Project for Allergic Diseases and Immunology (Research on Technology of Medical Transplantation) , 2016/04/01, 2017/03/31
  5. Research on Development of New Drugs, 2015/11/02, 2016/03/31
  6. Practical Research for Innovative Cancer Control, 2015/04/01, 2016/03/31
  7. Practical Research Project for Rare / Intractable Diseases, 2015/04/01, 2016/03/31
  8. Practical Research Project for Allergic Diseases and Immunology (Research on Technology of Medical Transplantation), 2015/04/01, 2016/03/31
  9. Health and Labour Sciences Research Grants, 2014/06/02, 2015/03/31
  10. Health and Labour Sciences Research Grants, 2014/06/02, 2015/03/31
  11. Health and Labour Sciences Research Grants, 2014/05/29, 2015/03/31
  12. KAKENHI, 2014, 2015
  13. KAKENHI, 2013, 2015
  14. 2012
  15. 2012
  16. 2011
  17. 2011
  18. 2010
  19. 2010
  20. 2010
  21. 2010
  22. KAKENHI, Application of humanized mice to analyses and therapeutics of phagocytic disorders, 2010, 2012
  23. 2008
  24. KAKENHI, The cell-surface modification enhances the engraftment of human CD34-positive cells into immunodeficient mice, 2007, 2008
  25. 2005
  26. KAKENHI, Basic research for the establishment of the intra-bone marrow stem cell transplantation, 2004, 2005
  27. KAKENHI, Purification, expansion, and reconstitution of mesodermal stemcells from human bone marrow, 2003, 2004
  28. KAKENHI, GENE EXPRESSIONS DURING PROLIFERATION AND DIFFERENTIATION OF MYELOID CELIS IN SEVERE CONCENITAL NEUTROPENIA, 2001, 2002
  29. KAKENHI, Identification of Human facilitating cells, 2001, 2002
  30. 2000
  31. KAKENHI, A study for a transcription factor gene regulating radiation sensitivity, 1999, 2000
  32. KAKENHI, EXPANSION OF HUMAN BONE MARROW CELLS CAPABLE OF REPOPULATING IN MICE BY COCULTURE WITH BONE MARROW STROMAL CELLS, 1999, 2000
  33. 1997
  34. KAKENHI, CHARACTERIZATION OF PURIFIED HUMAN HEMATOPOIETIC PROGENITOR CELLS OF BONE MARROW AND THEIR RECONSTITUTING ABILITY IN GENOGENEIC TRANSPLANTATION, 1997, 1998
  35. KAKENHI, 1993, 1993
  36. KAKENHI, 1990, 1990
  37. KAKENHI, 1989, 1989
  38. KAKENHI, 1986, 1986