HIROFUMI NARIYA

Last Updated :2019/12/02

Affiliations, Positions
Graduate School of Integrated Sciences for Life, ., Associate Professor
Web Site
E-mail
nariyahiroshima-u.ac.jp
Other Contact Details
Laboratory of Food Microbiology and Hygiene, Food Science and Biofunctions Division, Department of Biofunctional Science and Technology, Graduate School of Biosphere Science, Japan
TEL : (+81)82-424-7921 FAX : (+81)

Basic Information

Major Professional Backgrounds

  • 1996/04, 1997/03, Department of Applied Microbiology, Graduate School of Agricultural Science, Tohoku University, Research Fellow of the Japan Society for the Promotion of Science (DC)
  • 1997/04, 1998/03, Department of Applied Microbiology, Graduate School of Agricultural Science, Tohoku University, Research Fellow of the Japan Society for the Promotion of Science (PD)
  • 1998/05, 2001/04, Department of Biochemistry, University of Medicine and Dentistry of New Jersey (UMDNJ)-Robert Wood Johnson Medical School (RWJMS), USA, Postdoctoral Fellow
  • 2001/04, 2006/05, Department of Biochemistry, UMDNJ-RWJMS, USA, Research Teaching Specialist III
  • 2006/05, 2007/01, Department of Biochemistry, UMDNJ-RWJMS, USA, Adjunct Assistant Professor
  • 2007/02/16, 2016/09/30, Department of Microbiology, Faculty of Medicine, Kagawa University, Assistant Professor
  • 2016/10/01, 2019/03/31, Laboratory of Food Microbiology and Hygiene, Graduate School of Biosphere Science, Hiroshima University, Associate Professor

Educational Backgrounds

  • Tohoku university, Department of Applied Microbiology, Graduate School of Agricultural Science, Bioscience, Biotechnology, and Agrochemistry, Ph.D., Japan, 1997

Academic Degrees

  • TOHOKU UNIVERSITY
  • TOHOKU UNIVERSITY

Research Fields

  • Medicine,dentistry, and pharmacy;Basic medicine;Bacteriology (including mycology)
  • Agricultural sciences;Agricultural chemistry;Applied microbiology
  • Biology;Biological Science;Molecular biology

Research Keywords

  • Pathogenic bacteria, Food poisoning bacteria, Clostridia, Clostridium perfringens, Signal transduction systems, Protein kinases and phosphatases, Cell-wall lytic enzymes, Endolysins

Affiliated Academic Societies

  • The Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA), Japanese Society for Bacteriology (JSB), The American Society For Microbiology (ASM)

Educational Activity

Course in Charge

  1. 2019, Liberal Arts Education Program1, 4Term, Biological production and natural environment
  2. 2019, Liberal Arts Education Program1, 2Term, Life, food, and environmental sciences
  3. 2019, Undergraduate Education, 3Term, Public Health
  4. 2019, Undergraduate Education, Intensive, Laboratory Work in General Biology I
  5. 2019, Undergraduate Education, 2Term, Reading of Foreign Literature
  6. 2019, Undergraduate Education, 2Term, Introduction to Applied Biological Science I
  7. 2019, Undergraduate Education, 4Term, Introduction to Applied Biological Science II
  8. 2019, Undergraduate Education, Intensive, Laboratory Work in Food Hygiene
  9. 2019, Undergraduate Education, Academic Year, Graduation Thesis
  10. 2019, Undergraduate Education, 1Term, Food Microbiology
  11. 2019, Undergraduate Education, 3Term, Modern Food Science
  12. 2019, Graduate Education (Master's Program) , First Semester, Practice in Food Science and Biofunctions
  13. 2019, Graduate Education (Master's Program) , First Semester, Interdisciplinary Seminars(A)
  14. 2019, Graduate Education (Doctoral Program) , First Semester, Interdisciplinary Seminars(B)

Research Activities

Academic Papers

  1. Systemic method to isolate large bacteriophages for use in biocontrol of a wide-range of pathogenic bacteria, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 127(1), 73-78, 201901
  2. Occurrence of Salmonella genomic island 1 (SGI1) in two African Proteus mirabilis strains isolated from diseased chicken flocks, INFECTION GENETICS AND EVOLUTION, 62, 8-10, 201808
  3. Ethanolamine utilization supports Clostridium perfringens growth in infected tissues, Microbial Pathogenesis, 119, 200-207, 20180411
  4. Structures of major pilins in Clostridium perfringens demonstrate dynamic conformational change, ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 75, 718-732, 201908
  5. High Prevalence of Antimicrobial Resistance in Gram-Negative Bacteria Isolated from Clinical Settings in Egypt: Recalling for Judicious Use of Conventional Antimicrobials in Developing Nations, MICROBIAL DRUG RESISTANCE, 25(3), 371-385, 20190401
  6. An enhanced green fluorescence protein (EGFP)-based reporter assay for quantitative detection of sporulation in Clostridium perfringens SM101, INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 291, 144-150, 20190216
  7. X-ray structure of Clostridium perfringens sortase B cysteine transpeptidase, Biochemical and Biophysical Research Communications, 493(3), 1267-1272, 20170928
  8. First report in Africa of two clinical isolates of Proteus mirabilis carrying Salmonella genomic island (SGI1) variants, SGI1-PmABB and SGI1-W, Infection, Genetics and Evolution, 51, 132-137, 20170328
  9. Cleansing effect of acidic L-arginine on human oral biofilm, BMC Oral Health, 16(1), 40, 20160322
  10. DNA Inversion Regulates Outer Membrane Vesicle Production in Bacteroides fragilis, PLoS One, 11(2), e0148887, 20160209
  11. Katayama S, Tagomori M, Morita N, Yamasaki T, Nariya H, Okada M, Watanabe M and Hitsumoto Y: Determination of the Clostridium perfringens-binding site on fibronectin. Anaerobe, 34: 174-81. 2015., 2015
  12. Katayama S, Kato S, Yamasaki A, Aitani K, Yamasaki T, Hatano N, Nariya H and Hitsumoto Y: Novel cell wall-associated fibronectin-binding proteins of Clostridium perfringens. International Journal of Analytical Bio-Science, 3: 1-9. 2015., 2015
  13. Tamai E, Yoshida H, Sekiya H, Nariya H, Miyata S, Okabe A, Kuwahara T, Maki J and Kamitori S: X-ray structure of a novel endolysin encoded by episomal phage phiSM101 of Clostridium perfringens. Molecular Microbiology, 92: 326-337. 2014. (Cover Photo), 2014
  14. Yamaguchi Y, Nariya H, Park JH and Inouye M: Inhibition of specific gene expressions by protein-mediated mRNA interference. Nature Communications, 3: 607, 2012., 2012
  15. Nariya H, Miyata S, Kuwahara T and Okabe A: Development and characterization of a xylose-inducible gene expression system for Clostridium perfringens. Applied and Environmental Microbiology, 77: 8439-8441, 2011., 2011
  16. Nariya H, Miyata S, Tamai E, Sekiya H, Maki J and Okabe A: Identification and characterization of a putative endolysin encoded by episomal phage phiSM101 of Clostridium perfringens. Applied Microbiology and Biotechnology, 90: 1973-1979, 2011., 2011
  17. Tanaka H, Nariya H, Suzuki M, Houchi H, Tamai E, Miyata S and Okabe A: High-level production and purification of clostripain expressed in a virulence-attenuated strain of Clostridium perfringens. Protein Expression and Purification, 76: 83-89, 2011., 2011
  18. Nariya H, Miyata S, Suzuki M, Tamai E and Okabe A: Development and application of a method for counterselectable in-frame deletion in Clostridium perfringens. Applied and Environmental Microbiology, 77: 1375-1382, 2011., 2011
  19. Manabe S, Nariya H, Miyata S, Tanaka H, Minami J, Suzuki M, Taniguchi Y and Okabe A: Purification and characterization of a clostripain-like protease from a recombinant Clostridium perfringens culture. Microbiology, 156: 561-569, 2010., 2010
  20. Inouye S and Nariya H: Dual regulation with Ser/Thr kinase cascade and a His/Asp TCS in Myxococcus xanthus. Advances in Experimental Medicine and Biology, 631: 111-121, 2008. (Review), 2008
  21. Tamai E, Miyata S, Tanaka H, Nariya H, Suzuki M, Matsushita O, Hatano N and Okabe A: High-level expression of his-tagged clostridial collagenase in Clostridium perfringens. Applied Microbiology and Biotechnology, 80: 627-635, 2008., 2008
  22. Tanaka H, Tamai E, Miyata S, Taniguchi Y, Nariya H, Hatano N, Houchi H, Okabe A: Construction and characterization of a clostripain-like protease-deficient mutant of Clostridium perfringens as a strain for clostridial gene expression. Applied Microbiology and Biotechnology, 77: 1063-1071, 2008., 2008
  23. Zhu L, Phadtare S, Nariya H, Ouyang M, Husson RN and Inouye M: The mRNA interferases, MazF-mt3 and MazF-mt7 from Mycobacterium tuberculosis target unique pentad sequences in single-stranded RNA. Molecular Microbiology, 69: 559-569, 2008, 2008
  24. Nariya H and Inouye M: MazF, an mRNA interferase, mediates programmed cell death during multicellular Myxococcus development. Cell, 132: 55-66, 2008., 2008
  25. Nariya H and Inouye S: A protein Ser/Thr kinase cascade negatively regulates the DNA-binding activity of MrpC, a smaller form of which may be necessary for the Myxococcus xanthus development. Molecular Microbiology, 60: 1205-1217, 2006. (Cover Photo), 2006
  26. Nariya H and Inouye S: Factors that modulate the Pkn4 kinase cascade in Myxococcus xanthus. Journal of Molecular Microbiology and Biotechnology, 9: 147-153, 2005. (Review), 2005
  27. Nariya H and Inouye S: Identification of a protein Ser/Thr kinase cascade that regulates essential transcriptional activators in Myxococcus xanthus development. Molecular Microbiology, 58: 367-379, 2005. (Cover Banner and MicroCommentary 345-348), 2005
  28. Nariya H and Inouye S: Modulating factors for the Pkn4 kinase cascade in regulating 6-phosphofructokinase in Myxococcus xanthus. Molecular Microbiology, 56: 1314-1328, 2005., 2005
  29. Inouye M, Ke H, Yashio A, Yamanaka K, Nariya H, Shimamoto T and Inouye S: Complex formation between a putative 66-residue thumb domain of bacterial reverse transcriptase RT-Ec86 and the primer recognition RNA. Journal of Biological Chemistry, 279: 50735-50742, 2004., 2004
  30. Nariya H and Inouye S: An effective sporulation of Myxococcus xanthus requires glycogen consumption via Pkn4-activated 6-phosphofructokinase. Molecular Microbiology, 49: 517-528, 2003., 2003
  31. Nariya H and Inouye S: Activation of 6-phosphofructokinase via phosphorylation by Pkn4, a protein Ser/Thr kinase of Myxococcus xanthus. Molecular Microbiology, 46: 1353-1366, 2002., 2002
  32. Inouye S, Jain, R, Ueki T, Nariya H, Xu CY, Hsu MY, Fernandez-Luque BA, Munoz-Dorado J, Farez-Vidal E and Inouye M: A large family of eukaryotic-like protein Ser/Thr kinases of Myxococcus xanthus, a developmental bacterium. Microbial and Comparative Genomics (OMICS: A Journal of Integrative Biology), 5: 103-112, 2000., 2000
  33. 成谷宏文:ブドウ球菌ロイコシジンおよびγ-ヘモリジンの構造と血球崩壞機構に関する研究. 日本農芸化学会誌, 73: 109-115, 1999(総説), 1999
  34. Olson R, Nariya H, Yokota K, Kamio Y and Gouaux E: Crystal structure of staphylococcal LukF delineates conformational changes accompanying formation of a transmembrane channel. Nature Structural & Molecular Biology, 6: 134-140, 1999., 1999
  35. Yokota K, Sugawara N, Nariya H, Kaneko J, Tomita T and Kamio Y: Further study on the two pivotal parts of Hlg2 for the full hemolytic activity of staphylococcal gamma-hemolysin. Bioscience Biotechnology and Biochemistry, 62: 1745-1750, 1998., 1999
  36. 金子淳,成谷宏文,神尾好是:黄色ブドウ球菌の二成分蛋白質毒素 ロイコシジンとγヘモリジン遺伝子の起源と溶血機構の謎に迫る 化学と生物 (解説), 36(3): 160-167, 1998., 1998
  37. Nishiyama A, Nariya H and Kamio Y: Phosphorylation of LukS by protein kinase A is crucial for the LukS-specific function of the staphylococcal leukocidin on human polymorphonuclear leukocytes. Bioscience Biotechnology and Biochemistry, 62: 1834-1838, 1998., 1998
  38. Nariya H, Shimatani A, Tomita T and Kamio Y: Identification of the essential amino acid residues in LukS for the hemolytic activity of staphylococcal leukocidin towards rabbit erythrocytes. Bioscience Biotechnology and Biochemistry, 61: 2095-2099, 1997., 1997
  39. Nariya H and Kamio Y: Identification of the minimum segment essential for the H gamma II-specific function of staphylococcal gamma-hemolysin. Bioscience Biotechnology and Biochemistry, 61: 1786-1788, 1997., 1997
  40. Nariya H, Nishiyama A and Kamio Y: Identification of the minimum segment in which the threonine246 residue is a potential phosphorylated site by protein kinase A for the LukS-specific function of staphylococcal leukocidin. FEBS Letters, 415: 96-100, 1997., 1997
  41. 成谷宏文,神尾好是: 黄色ブドウ球菌の2成分タンパク質毒素 ロイコシジンとγ-ヘモリジンの構造と毒素活性発現. 化学と生物(今日の話題), 33(11): 701-703, 1995., 1995
  42. Nariya H and Kamio Y: Identification of the essential regions for LukS- and H gamma II-specific functions of staphylococcal leukocidin and gamma-hemolysin. Bioscience Biotechnology and Biochemistry, 59: 1603-1604, 1995., 1995
  43. Ozawa T, Kaneko J, Nariya H, Izaki K and Kamio Y: Inactivation of gamma-hemolysin H gamma II component by addition of monosialoganglioside GM1 to human erythrocyte. Bioscience Biotechnology and Biochemistry, 58: 602-605, 1994., 1994
  44. Nariya H, Asami I, Ozawa T, Izaki K and Kamio Y: Improved method for purification of leukocidin and gamma-hemolysin components from Staphylococcus aureus. Bioscience Biotechnology and Biochemistry, 57: 2198-2199, 1993., 1993
  45. Nariya H, Izaki K and Kamio Y: The C-terminal region of the S component of staphylococcal leukocidin is essential for the biological activity of the toxin. FEBS Letters, 329: 219-222, 1993., 1993
  46. Kamio Y, Rahman A, Nariya H, Ozawa T and Izaki K: The two Staphylococcal bi-component toxins, leukocidin and gamma-hemolysin, share one component in common. FEBS Letters, 321: 15-18, 1993., 1993
  47. Rahman A, Nariya H, Izaki K, Kato I and Kamio Y: Molecular cloning and nucleotide sequence of leukocidin F-component gene (lukF) from methicillin resistant Staphylococcus aureus. Biochemical and Biophysical Research Communications, 184: 640-646, 1992., 1992

Publications such as books

  1. 2007, Inouye S, Nariya H and Munoz-Dorado J: Protein Ser/Thr kinases and phosphatases in M. xanthus. Chapter 11 In “Myxobacteria: Multicellularity and Differentiation” (Edi.) Whitworth D, pp 191-210/552, ASM Press, Washington DC, 2007, 2007
  2. 2008, Inouye S and Nariya H: Dual regulation with Ser/Thr kinase cascade and a His/Asp TCS in Myxococcus xanthus.In “Bacterial Signal Transduction: Networks and Drug Targets” (Edi.) Utsumi, Ryutaro, pp 111-121/242, Springer-Verlag, New York, 2008, 2008

Invited Lecture, Oral Presentation, Poster Presentation

  1. Biochemical and structural analysis of Clostridium perfringens Cell wall lytic enzyme CPE1138, Eiji Tamai, Shigehiro Kamitori, Hirofumi Nariya, Hiroshi Sekiya, Azusa Watanabe, Jun Maki, The 139th Annual Meeting of the Pharmaceutical Society of Japan (AMPSJ), 2019/03/20, Without Invitation, Kimiko Makino (Tokyo Univ.), Makuhari Messe, Chiba
  2. A Novel Approach to Bio-control Food Poisoning Bacteria using Specific Phage-derived Endolysins, Hirofumi Nariya, The 6th Annual Meeting for Structural and Molecular Microbiology, 2019/03/08, With Invitation, Shigehiro Kamitori (Kagawa Univ.), Kagawa Univ., Kagawa
  3. Development of a Single-tube Eicosaplex-PCR for the Effective Detection of β-Lactamase Genes in Enterobacteriaceae, Ahmed M. Soliman, Toshi Shimamoto, Tadashi Shimamoto, Hirofumi Nariya, 2018/10/06, Without Invitation
  4. X-ray structure of Clostridium perfringens CPE1138 catalytic domain hydrolyzing bacterial cell wall, Shigehiro Kamitori, Eiji Tamai, Hiroshi Sekiya, Jun Maki, Hirofumi Nariya, The 91st Annual Meeting of the Japanese Biochemical Society, 2018/09/24, Without Invitation, Akira Kikuchi (Osaka University), Kyoto International Conference Center, Kyoto
  5. Functional characterization of the Arc two-component signal transduction system in Vibrio cholerae, Toshi Shimamoto, Zhiqun Yan, Hirofumi Nariya, Tadashi Shimamoto, U. S. – Japan Cooperative Medical Science Program, Panel Conference of Cholera and Other Bacterial Enteric Infection, 2018/08/07, Without Invitation, Mitsuaki Nishibuchi (Kyoto University), Kyoto University, Kyoto
  6. Biocontrol of Clostridium perfringens by using two types of specific endolysins, Maho Okada, Eiji Tamai, Hiroshi Sekiya, Toshi Shimamoto, Tadashi Shimamoto, Hirofumi Nariya, The 91st Annual Meeting of Japanese Society for Bacteriology (JSB), 2018/03/27, With Invitation, Testuya Hayashi (Kyusyu Univ.), Fukuoka, Japan
  7. Effect of salt concentration on the development of VBNC state of Vibrio cholerae, Toshi Shimamoto, Hirofumi Nariya, Tadashi Shimamoto, The 91st Annual Meeting of Japanese Society for Bacteriology (JSB), 2018/03/27, With Invitation, Tetsuya Hayasi (Kyusyu Univ.), Fukuoka, Japan
  8. First detection of Salmonella genomic island 1 variant in Providencia stuartii clinical isolate, Ahmed M. Soliman, Toshi Shimamoto, Hirofumi Nariya, Tadashi Shimamoto, The 91st Annual Meeting of Japanese Society for Bacteriology (JSB), 2018/03/27, Without Invitation, Tetsuya Hayasi (Kyusyu Univ.), Fukuoka, Japan
  9. Deletion of NADH-dependent dehydrogenase genes in C. perfringens to enhance hydrogen production, Keina Nakamura, Hirofumi Nariya, Ryuichi Moriyama, Shigeru Miyata, 第91回日本細菌学会総会, 2018/03/27, Without Invitation, Tetsuya Hayasi (Kyusyu Univ.), Fukuoka, Japan
  10. The gene promoters of the fibronectin-binding proteins, FbpC and FbpD, of Clostridium perfringens, Tomomi Kawai, Kaoru Komoto, Ayumu Yamasaki, Hirofumi Nariya, Tadashi Shimamoto, Yasuo Hitsumoto, Seiichi Katayama, The 91st Annual Meeting of Japanese Society for Bacteriology (JSB), 2018/03/27, Without Invitation, Tetsuya Hayasi (Kyusyu Univ.), Fukuoka, Japan
  11. Anti-noroviral effect of Chinese quince (Pseudocydonia sinensis), Chiahua Chan, Maki Kamimoto, Yukie Fujisaka, Hirotsugu Iwano, Toshi Shimamoto, Hirofumi Nariya, Tadashi Shimamoto, The 2018 Annual Meeting of the Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA), 2018/03/16, Without Invitation, Tetsuo Kobayasi (Nagoya Univ.), Nagoya, Japan
  12. Biocontrol of Clostridium perfringens by using two types of specific endolysins, Hirofumi Nariya, The 5th Annual Meeting for Structural and Molecular Microbiology, 2018/03/09, With Invitation, Shigehiro Kamitori (Kagawa Univ.), Kagawa, Japan
  13. X-ray structure of Clostridium perfringens pili protein CppA, Shigehiro Kamitori, Eiji Tamai, Hiroshi Sekiya, Jun Maki, Hirofumi Nariya, Consortium of Biological Sciences 2017(ConBio2017), 2017/12/06, Without Invitation, Kobe, Japan
  14. Biocontrol of Clostridium perfringens by using two types of specific endolysins, Hirofumi Nariya, Maho Okada, Eiji Tamai, Tadashi Shimamoto, 46th Annual Meeting of Food and Agriculture Panel United States-Japan Cooperative Program in Natural Resources (UJNR), 2017/11/14, With Invitation, Hiroshima, Japan
  15. Analysis of Physiological Functions of galR-lacZ Cluster in Vibrio cholerae, Taiki Tamura, Hirofumi Nariya, Toshi Shimamoto, Tadashi Shimamoto, 2017/10/14, Without Invitation
  16. Functional characterization of the oxygen-regulated two-component system, ArcAB, in Vibrio cholerae, Zhiqun Yan, Hirofumi Nariya, Toshi Shimamoto, Tadashi Shimamoto, U. S. – Japan Cooperative Medical Science Program Panel Conference of Cholera and Other Bacterial Enteric Infections, 2017/08/08, Without Invitation, Kyoto, Japan
  17. Analyses of the fibronectin-binding proteins in the peptidoglycan layer of Clostridium perfringens, Seiichi Katayama, Ayumu Yamasaki, Kaoru Koumoto, Hirofumi Nariya, Yasuo Hitsumoto, 10th International Conference on the Molecular Biology and Pathogenesis of the Clostridia (Clostpath10), 2017/08/07, Without Invitation, Michigan League, MI, USA
  18. Eukaryotic protein kinase and phosphatase regulate morphology of Clostridium perfringens, Hirofumi Nariya, Eiji Tamai, Tadashi Shimamoto, The 90th Annual Meeting of Japanese Society for Bacteriology, 2017/03/19, Without Invitation, Takaaki Akaike (Tohoku University Graduate School of Medicine), Sendai International Center
  19. Emergence of SGI1-positive Proteus mirabilis clinical isolates in Egypt, Ahmed M. Soliman, Ashraf M. Ahmed, Toshi Shimamoto, Ramadan A. El-Domany, Hirofumi Nariya, Tadashi Shimamoto, The 90th Annual Meeting of Japanese Society for Bacteriology, 2017/03/19, Without Invitation, Takaaki Akaike (Tohoku University Graduate School of Medicine), Sendai International Center
  20. Analysis of the domains of fibronectin-binding proteins (FbpC, FbpD) of Clostridium perfringens, Kaoru Komoto, Hirofumi Nariya, Yasuo Hitsumoto, Seiichi Katayama, The 90th Annual Meeting of Japanese Society for Bacteriology, 2017/03/19, Without Invitation, Takaaki Akaike (Tohoku University Graduate School of Medicine), Sendai International Center
  21. Development of novel expression system using codonmodified T7 RNAP and Xyl-uptake system for clostridial gene, Shunya Sawairi, Hirofumi Nariya, Kazue Nakane, Shigeru Miyata, The 90th Annual Meeting of Japanese Society for Bacteriology, 2017/03/19, Without Invitation, Takaaki Akaike (Tohoku University Graduate School of Medicine), Sendai International Center
  22. Construction of plasmid pXM derivative for genome editing of Clostridium perfringens, Yuya Fujita, Keina Nakamura, Shunya Sawairi, Hirofumi Nariya, Shigeru Miyata, The 90th Annual Meeting of Japanese Society for Bacteriology, 2017/03/19, Without Invitation, Takaaki Akaike (Tohoku University Graduate School of Medicine), Sendai International Center
  23. Eukaryotic protein kinase and phosphatase regulate morphology of Clostridium perfringens, Hirofumi Nariya, The 4th Annual Meeting for Structural and Molecular Microbiology, 2017/03/10, With Invitation, Shigehiro Kamitori (Kagawa Univ.), Kagawa Univ., Kagawa
  24. Identification of two cell wall–associated fibronectin-binding proteins of Clostridium perfringens., Yamasaki A, Kato S, Aitani K, Yamasaki T, Hatano N, Nariya H, Hitsumoto Y, Katayama S, 9th International Conference on the Molecular Biology and Pathogenesis of the Clostridia., 2015/09/07, Without Invitation, Freiburg, Germany
  25. Determination of binding site for Clostridium perfringens on fibronectin., Katayama S, Tagomori M, Yamashita H, Yamasaki T, Nariya H, Okada M, Watanabe M, Hitsumoto Y, 8th International Conference on the Molecular Biology and Pathogenesis of the Clostridia 2013, 2013/10/22, Without Invitation, Palm Cove, Queensland, Australia
  26. Development and characterization of a xylose-inducible gene expression system for Clostridium perfringens., Nariya H, Miyata S, Okabe A, XIII International Congress of Bacteriology and Applied Microbiology, International Union of Microbiological Societies Congresses 2011, 2011/09/08, Without Invitation, Sapporo, Japan
  27. High-level production and purification of clostripain expressed in a virulence-attenuated strain of Clostridium perfringens, Tanaka H, Nariya H, Suzuki M, Miyata S, Tamai E, Kosaka S, Fukuoka N, Houchi H and Okabe A, XIII International Congress of Bacteriology and Applied Microbiology, International Union of Microbiological Societies Congresses 2011, 2011/09/08, Without Invitation, Sapporo, Japan
  28. Function of the phased A-tracts upstream the promoter of the phospholipase c gene on the gene expression in Clostridium perfringens., Katayama S, Tanaka C, Hashikawa N Ishibashi K, Nakamura D and Nariya H, XIII International Congress of Bacteriology and Applied Microbiology, International Union of Microbiological Societies Congresses 2011, 2011/09/06, Without Invitation, Sapporo, Japan
  29. Clostridial expression system., Miyata S, Nariya H, Tamai E, Moriyama R and Okabe A, 6th International Conference on Gram-Positive Microorganisms, 2011/01/20, Without Invitation, Montecatini Terme, Tuscany, Italy
  30. Pkn2 is a receptor adenylyl cyclase that is auto-regulated by phospholytation during development of Myxococcus xanthus., Nariya H and Inouye S, The 32nd International Conference on the Biology of the Myxobacteria, 2005/07/10, Without Invitation, Harrison Hot Spring, British Columbia, Canada
  31. Myxococcus xanthus protein Ser/Thr kinases (PSTKs)., Nariya H and Inouye S, The 31st International Conference on the Biology of the Myxobacteria, 2004/07, Without Invitation, Elsinore, Denmark
  32. Myxococcus xanthus protein Ser/Thr kinases., Nariya H and Inouye S, The 30th International Conference on the Biology of the Myxobacteria, 2003/07, Without Invitation, Long Beach, California, USA
  33. The multi-protein Ser/Thr kinase network in Myxococcus xanthus., Nariya H and Inouye S, The 29th International Conference on the Biology of the Myxobacteria, 2002/07/07, Without Invitation, Quebec, Canada
  34. Phosphorylation of phosphofructokinase by Pkn4, a protein Ser/Thr kinase and development of M. xanthus., Nariya H and Inouye S, The 26th International Conference on the Biology of the Myxobacteria, 1999, Without Invitation, Oregon, USA
  35. Unique features and phylogenetic analysis of protein Ser/Thr kinases of Myxococcus xanthus., Inouye S, Jain, R and Nariya H, The 25th International Conference on the Biology of the Myxobacteria, 1998/06/21, Without Invitation, Arahova, Greece
  36. Identification of the essential regions for LukS- and H gamma II-specific functions of staphylococcal leukocidin and gamma-hemolysin., Nariya H and Kamio Y, The 8th International Symposium on Staphylococci and Staphylococcal Infections, 1996/06/23, Without Invitation, Aix-les-Bains, France

Awards

  1. 2018年03月28日, The 91st Annual Meeting of Japanese Society for Bacteriology, Best Presentation Award, Japanese Society for Bacteriology (JSB), Biocontrol of Clostridium perfringens by using two types of specific endolysins
  2. 2017年03月20日, The 90th Annual Meeting of Japanese Society for Bacteriology, Best Presentation Award, Japanese Society for Bacteriology (JSB), Development of novel expression system using codonmodified T7 RNAP and Xyl-uptake system for clostridial gene
  3. 1998年04月01日, JSBBA, Award for Young Scientists 1998, The Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA), Study on the two Staphylococcal bi-component toxins, leukocidin and gamma-hemolysin

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2018, 2020

Social Activities

Organizing Academic Conferences, etc.

  1. 2017/10, 2017/10

History as Peer Reviews of Academic Papers

  1. 2017, Microbiology and Immunology