Katsuyuki Kozai

Last Updated :2020/04/01

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Dentistry & Oral Health Sciences), ., Professor
E-mail
kozaihiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Doctor of Philosophy in Dental Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Orthodontics / Pediatric dentistry

Research Keywords

  • mutans streptococci|questionaire
  • oral prophylaxis|mutanus streptococci
  • DNA figerprint
  • oral
  • dental caries
  • dietary life
  • intra-familiar transmission
  • periodontal disease in child
  • scanner
  • oleanolic acid

Educational Activity

Course in Charge

  1. 2020, Liberal Arts Education Program1, 2Term, General Health and Oral Sciences I
  2. 2020, Undergraduate Education, 4Term, Overview of Dentistry
  3. 2020, Undergraduate Education, 4Term, Medical Informatics
  4. 2020, Undergraduate Education, 1Term, Topics in Denral Research
  5. 2020, Undergraduate Education, 2Term, Topics in Denral Research
  6. 2020, Undergraduate Education, 4Term, Pediatric Dentistry
  7. 2020, Undergraduate Education, 1Term, Pediatric Dentistry
  8. 2020, Undergraduate Education, 2Term, Advanced Course in Growth and Development of Occlusion
  9. 2020, Undergraduate Education, First Semester, Dental Research Practices
  10. 2020, Undergraduate Education, 3Term, Basic Practice of Pediatric Dentistry
  11. 2020, Undergraduate Education, 4Term, Basic Practice of Pediatric Dentistry
  12. 2020, Undergraduate Education, 3Term, Disaster Dentistry and Forensic Odontology
  13. 2020, Undergraduate Education, Second Semester, Dental Research Practices
  14. 2020, Undergraduate Education, 2Term, Special Subject
  15. 2020, Undergraduate Education, 2Term, Pediatrics
  16. 2020, Undergraduate Education, 1Term, Seminar and Practice of Pediatric Dentistry
  17. 2020, Undergraduate Education, 2Term, General Seminar on Clinical Dentistry
  18. 2020, Undergraduate Education, Academic Year, Clinical Practice (Pedodontics)
  19. 2020, Undergraduate Education, 4Term, Medical Informatics
  20. 2020, Undergraduate Education, 2Term, Pediatrics
  21. 2020, Undergraduate Education, 3Term, Disaster Dentistry and Forensic Odontology
  22. 2020, Undergraduate Education, 4Term, Medical Informatics
  23. 2020, Undergraduate Education, 2Term, Pediatric Dentistry
  24. 2020, Undergraduate Education, 3Term, Practice of Pediatric Dentistry
  25. 2020, Undergraduate Education, 3Term, Disaster Dentistry and Forensic Odontology
  26. 2020, Graduate Education (Doctoral Program) , First Semester
  27. 2020, Graduate Education (Doctoral Program) , First Semester, Advanced seminar on Pediatric Dentistry
  28. 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced seminar on Pediatric Dentistry
  29. 2020, Graduate Education (Doctoral Program) , First Semester, Training course for specialist of pediatric dentistry
  30. 2020, Graduate Education (Doctoral Program) , Second Semester, Training course for specialist of pediatric dentistry
  31. 2020, Graduate Education (Doctoral Program) , First Semester, Advanced research on Pediatric Dentistry
  32. 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced research on Pediatric Dentistry
  33. 2020, Graduate Education (Doctoral Program) , First Semester
  34. 2020, Graduate Education (Doctoral Program) , Second Semester
  35. 2020, Graduate Education (Doctoral Program) , First Semester
  36. 2020, Graduate Education (Doctoral Program) , Second Semester
  37. 2020, Graduate Education (Doctoral Program) , 1Term, Cause of Death Investigation
  38. 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Forensic Dentistry
  39. 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Forensic Dentistry
  40. 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Forensic Dentistry
  41. 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Forensic Dentistry

Research Activities

Academic Papers

  1. Intrafamilial distribution of mutans streptococci in Japanese families and possibility of father-to-child transmission, Microbiology and Immunology, 43(2), 99-106, 19990201
  2. Initial acquisition of mutans streptococci in children at day nursery., Journal of Dentistry for Children., 69(3), 284-288, 20020901
  3. Changes in Strains of Mutans Steptococci Induced by Treatment with Chlorhexidine Varnish, Journal of Dental Research, 70(9), 1252-1257, 19910401
  4. Inhibition of glucosyltransferase from Streptococcus mutans by oleanolic acid and ursolic acid, Caries Research, 21(2), 104-108, 19870401
  5. Effect of oleanolic acid-cyclodextrin inclusion compounds on dental caries by in vitro experiment and rat-caries model, Microbios, 97, 179-188, 19990401
  6. Analysis of inhibition of insoluble glucan synthesis by an oleanolic acid-b-cyclodextrin inclusion compound, Pediatric Dental Journal, 5(1), 83-86, 19950401
  7. Residual contamination of toothbrushes by microorganisms, Journal of Dentistry for Children., 56(3), 201-204, 19890401
  8. Prevention of dental caries by oriental folk medicines-active principles of Zizyphi Fructus for inhibition of insoluble glucan formation by cariogenic bacterium Streptococcus mutans, Planta Medica, 119-120, 19860401
  9. In vitro study of antibacterial and antiadhesive activities of fluoride-containing light-cured fissure sealants and a glass ionomer liner/base against oral bacteria, Journal of Dentistry for Children., 67(2), 117-122, 20000301
  10. New tongue protector to prevent decubital lingual ulcers caused by tongue thrust with myoclonus, Journal of Dentistry for Children., 65(6), 474-477, 19980401
  11. The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures, PROSTAGLANDINS & OTHER LIPID MEDIATORS, 97(3-4), 97-102, MAR 2012
  12. Prevention of Dental Caries by Oriental Folk Medicines-Active Principles of Zizyphi Fructus for Inhibition of Insoluble Glucan Formation By Cariogenic Bacterium S. mutans, Planta Medica(Journal of Medical Plant Research), 2, 19860401
  13. Effect of oleanolicacid-cyclodextrin inclusion compounds on dental carries by invitro experiment and rat carries model, Microbios, 97, 179-188, 19990401
  14. Effect of Gambir Extract on Dental Plaque Formation, J. Dent. Res., 74(S), 499, 19950401
  15. Inhibition of glucosyltransferase activity from Streptococcus mutans by various crude drug extracts, Microbios Letters, 26, 105-108, 19840401
  16. Effect of Oleanolic Acid on Dental Caries in Rats, J. Dent. Res., 73(S), 415, 19940401
  17. Study of Mutaus Streptococci Transmission in Japanese Families, Journal of Dental Research, 76(IADRAbstracts), 108, 19970401
  18. Potential of gambir as an inhibitor of dental plaque formation, Maj. Ked. Gigi (Dental Journal), 28(3), 95-96, 19950401
  19. Inhibition of insoluble glucan synthesis and growth of mutans streptococci by oleanolic acid-b-cyclodextrin inclusion compounds., Proceedings of 13th congress of International Association of Dentistry for Children, 283, 19910401
  20. The efficacy of an oral rating index for children for screening gingival health and oral hygiene status, Pediatric Dental Journal, 9(1), 91-97, 19990701
  21. Initial acquisition and transmission of mutans streptococci in children at day nursery, Proceeding of the 8th scientific meeting=Indonesian students association in Japan=, 289-292, 19990901
  22. A two-year longitudinal study of periodontal condition in early adolescence, 8(1), 139-142, 19980401
  23. Epidemiological survey on periodontal conditions in children, Proceedings of the 1st Conference of Pediatric Dentistry Association of Asia, 174-175, 19971001
  24. Anticariogenic potential in various species of tea, Proceedings of the 1st Conference of Pediatric Dentistry Association of Asia, 186-187, 19970401
  25. A pilot study on the cleanliness of toothbrushes, Pediatric Dental Journal, 7(1), 115-116, 19970401
  26. A long-term survey of methicillin-resistant Staphylococcus aureus in the oral cavity of children, Microbiolgy and Immunology, 41(9), 681-686, 19970401
  27. Localized aggressive periodontitis in primary dentition: a case report., Journal of Periodontology, 74, 1060-1066, 20030401
  28. PCR detection of Streptococcus mutans and S. sobrinus in dental plaque samples from Japanese pre-school children, Journal of Medical Microbiology, 51, 443-447, 20020401
  29. Intra-familial distribution of nine putative periodontopathogens in dental plaque., Journal of Oral Science, 46(3), 149-156, 20040401
  30. Subgingival distribution of Campylobacter rectus and Tannerella forsythensis in healthy children with primary dentiton, Archives of Oral biology, 51(1), 10-14, 20060401
  31. Mineralized tissue cells are principal source of FGF23, Bone, 40, 1565-1573, 20070401
  32. Stanniocalcin 1 acts as a paracrine regulator of gorowth plate chondrogenesis., Journal of Biological Chemistry, 281, 5120-5127, 20060601
  33. Long-term periodical isolation of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus(MRSA) from Japanese chiredren's oral cavities, Pediatric Dental Journal, 17(2), 127-130, 20070925
  34. Zymographic characterization of bacteriolytic enzymes produced by oral streptococci., Microbiol Immunol, 48, 465-469, 20040501
  35. Identification and molecular characterization of an N-Acetylmuraminidase, Aml, involved in Streptococcus mutans cell separation., Microbiol. Immunol., 50(9), 729-742, 20061001
  36. The prostaglandin receptors, EP2 and EP4, play different roles in osteoblast-adipocyte fate choices in the rat calvaria cell model., Journal of Bone and Mineral Research, 21, S254, 20061010
  37. EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures, Bone, 44, 1177-1185, 20090221
  38. Overexpression of fibroblast growth factor 23 suppresses osteoblast differentiation and matrix mineralization in vitro., Journal of Bone and Mineral Research, 20080601
  39. Chemotherapy and radiation against neuroblastoma inhibit forming of permanent teeth, Hiroshima Conference on Education and Science in Dentistry, 20070901
  40. Expression and function of variants of human catecholamine transporters lacking the fifth transmembrane region encoded by exon 6, PLoS One, 5(8), pii: e11945, 20100801
  41. Effectiveness of salivary chromogranin A as a stress index in young children during dental treatment, Pediatric dental journal, 22(2), 163-169, 20120901
  42. Comparative analyses of pediatric dental measurements using plaster and three-dimensional digital models, Eur J Paediatr Dent, 15(2), 137-142, 20140601
  43. In vitro study of antibacterial and antiadhesive activities of fluoride-containing light-cured fissure sealants and a glass ionomer liner/base against oral bacteria, JOURNAL OF DENTISTRY FOR CHILDREN, 67(2), 117-+, MAR-APR 2000
  44. PCR detection of Streptococcus mutans and S-sobrinus in dental plaque samples from Japanese pre-school children, JOURNAL OF MEDICAL MICROBIOLOGY, 51(5), 443-447, MAY 2002
  45. Localized aggressive periodontitis in primary dentition: A case report, JOURNAL OF PERIODONTOLOGY, 74(7), 1060-1066, JUL 2003
  46. Longitudinal study of dental caries incidence associated with Streptococcus mutans and Streptococcus sobrinus in pre-school children, JOURNAL OF MEDICAL MICROBIOLOGY, 54(7), 661-665, JUL 2005
  47. Subgingival distribution of Campylobacter rectus and Tannerella forsythensis in healthy children with primary dentition, ARCHIVES OF ORAL BIOLOGY, 51(1), 10-14, JAN 2006
  48. Correlation between genotype and supernumerary tooth formation in cleidocranial dysplasia, ORTHODONTICS & CRANIOFACIAL RESEARCH, 13(4), 197-202, NOV 2010
  49. Expression and Function of Variants of Human Catecholamine Transporters Lacking the Fifth Transmembrane Region Encoded by Exon 6, PLOS ONE, 5(8), AUG 5 2010
  50. Comparative analyses of paediatric dental measurements using plaster and three-dimensional digital models, EUROPEAN JOURNAL OF PAEDIATRIC DENTISTRY, 15(2), 137-142, JUN 2014
  51. Treatment of ectopic eruption of permanent mandibular first molars with innovative dental appliances, EUROPEAN JOURNAL OF PAEDIATRIC DENTISTRY, 15(2), 181-183, JUL 2014
  52. Infection with Porphyromonas gingivalis Exacerbates Endothelial Injury in Obese Mice, PLOS ONE, 9(10), OCT 21 2014
  53. Application of three-dimensional digital models for the morphometric analysis of predentition plasters: accuracy and precision, EUROPEAN JOURNAL OF PAEDIATRIC DENTISTRY, 15(4), 360-366, 2014
  54. Prevalence of Porphyromonas gingivalis fimA genotypes in Japanese children, JOURNAL OF ORAL SCIENCE, 54(1), 77-83, MAR 2012
  55. Effectiveness of aspartate aminotransferase as a marker of periodontal disease in children and adolescents, Pediatric dental journal, 24(1), 17-21
  56. Possible involvement of enolase in fluoride resistance in Streptococcus mutans, Pediatric dental journal, 24(1), 12-16
  57. Dental Infection of Porphyromonas gingivalis Induces Preterm Birth in Mice, PLOS ONE, 10(8), AUG 31 2015
  58. Role of MSX1 in Osteogenic Differentiation of Human Dental Pulp Stem Cells, STEM CELLS INTERNATIONAL, 2016
  59. Comparative proteome analysis of wild-type and klotho-knockout mouse kidneys using a combination of MALDI-IMS and LC-MS/MS, PROTEOMICS CLINICAL APPLICATIONS, 11(7-8), JUL 2017
  60. The relationship between lip-closing strength and the related factors in a cross-sectional study, PEDIATRIC DENTAL JOURNAL, 27(3), 115-120, DEC 2017
  61. Three-dimensional longitudinal changes of maxilla and mandible morphology during the predental period, EUROPEAN JOURNAL OF PAEDIATRIC DENTISTRY, 18(2), 139-144, 2017
  62. Galectin-3 Plays an Important Role in Preterm Birth Caused by Dental Infection of Porphyromonas gingivalis, SCIENTIFIC REPORTS, 8, FEB 12 2018
  63. An exploratory study of the factors related to mouth breathing syndrome in primary school children, ARCHIVES OF ORAL BIOLOGY, 92, 57-61, AUG 2018
  64. Soluble Klotho causes hypomineralization in Klotho-deficient mice, JOURNAL OF ENDOCRINOLOGY, 237(3), 285-300, JUN 2018
  65. Clinical Analysis of Replantaion of Avulsed Primary Teeth in Infancy, Journal of Japan Association of Dental Traumatology, 13(1), 29-36, 2017, 12, 31
  66. Investigation of pediatric specifications for the Salivary Multi Test (R) saliva test system, PEDIATRIC DENTAL JOURNAL, 28(3), 148-153, 201812
  67. Method of intraoral management for children with systemic disease based ion the salivary test, Japanese Journal of Dental Welfare, 23(1), 21-25, 2018, 6, 30
  68. A Research analysis of the Thrombocytopenia patient with Compound odontoma in the maxillary primary canine, Japanese Journal of Dental Welfare, 23(1), 26-33, 2018, 6, 30
  69. Dental hygienist intervention is an effective treatment for the oral symptoms with somatic symptom disorder and delusional disorder, A case report, Journal of Psychosomatic Oral Medicine, 33(1), 15-20, 2018, 6, 25
  70. Preliminary Survey to Establish Indicator fbr Screening of Primary School-age Children Who Require Welfare Assistance, Japanese Journal of Pediatric Dentistry, 56(1), 33-41, 2018
  71. Eruptive Disorder of tooth, 71(supplement), 433-437, 2018