Kazuaki Chayama

Last Updated :2017/09/13

Affiliations, Positions
Graduate School of Biomedical & Health Sciences (Biomedical Sciences Major), Professor
Web Site
E-mail
chayamahiroshima-u.ac.jp
Self-introduction
Since I became a Professor of the Faculty of Medicine, Hiroshima University, in September, 2000 and the head Professor of the Division of Gastroenterology of Hiroshima University Hospital in April 2002, our laboratory has evolved steadily as the result of the hard work of its doctors, staff and graduate students in the field of medical examination, education and research. We really appreciate the support of persons concerned with these activities.

Basic Information

Major Professional Backgrounds

  • 1981/05/01, Medical corporation Dojinkai, Clinical Fellow
  • 1986/04/01, National Public Officers Mutual Aid Association Federation, Clinical Fellow
  • 1996/07/01, same, Medical director
  • 2000/09/01, 2002/03/31, Hiroshima University, Faculty of Medicine, Professor
  • 2002/04/01, Hiroshima University, Graduate School of Biomedical Sciences , Professor
  • 2005/04/01, 2011/03/31, Hiroshima University, Hospital, Deputy Director
  • 2009/04/01, 2011/03/31, Hiroshima University, Vice Executive
  • 2011/04/01, 2015/03/31, Hiroshima University, Hospital, Director
  • 2012/04/01, 2015/03/31, Hiroshima University, Executive and Vice President
  • 2015/04/01, 2016/03/31, Hiroshima University, Special Assistant to the President

Educational Backgrounds

  • Hiroshima University, Faculty of Medicine, Japan, 1974/04, 1981/03

Academic Degrees

  • Doctor of Philosophy in Medical Sciences, The University of Tokyo

Educational Activity

  • School of Medicine:Program of Medicine, Graduate School of Biomedical & Health Sciences:Biomedical Sciences Major

In Charge of Primary Major Programs

  • Dentistry
  • Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Gastroenterology

Research Keywords

  • nucleotide sequence|Hepatitis-B
  • epigenetics
  • liver cirrhosis
  • driver mutation
  • deep sequence
  • whole genome analysisi
  • Hepatitis-C
  • whole genome sequencing
  • hepatitis
  • hepatocellular carcinoma

Affiliated Academic Societies

Educational Activity

Course in Charge

  1. 2017, Undergraduate Education, Intensive, Clinical diagnosis and treatment I
  2. 2017, Undergraduate Education, Intensive, Practice for medical research
  3. 2017, Undergraduate Education, Intensive
  4. 2017, Undergraduate Education, Intensive, Clinical Clerkship (Advanced Course)
  5. 2017, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
  6. 2017, Undergraduate Education, First Semester, Internal Medicine I
  7. 2017, Graduate Education (Doctoral Program) , First Semester, Advanced research on Gastroenterology and Metabolism
  8. 2017, Graduate Education (Doctoral Program) , Second Semester, Advanced research on Gastroenterology and Metabolism
  9. 2017, Graduate Education (Doctoral Program) , First Semester, Advanced seminar on Gastroenterology and Metabolism
  10. 2017, Graduate Education (Doctoral Program) , Second Semester, Advanced seminar on Gastroenterology and Metabolism

Research Activities

Academic Papers

  1. Clinical usefulness of transabdominal ultrasonography prior to patency capsule for suspected small-bowel strictures, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 51(3), 281-287, MAR 3 2016
  2. Novel pH-sensitive multifunctional envelope-type nanodevice for siRNA-based treatments for chronic HBV infection, JOURNAL OF HEPATOLOGY, 64(3), 547-555, MAR 2016
  3. Computer-aided diagnosis of colorectal polyp histology by using a real-time image recognition system and narrow-band imaging magnifying colonoscopy, GASTROINTESTINAL ENDOSCOPY, 83(3), 643-649, MAR 2016
  4. Long-term outcomes after treatment for T1 colorectal carcinoma, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 31(3), 571-578, MAR 2016
  5. Effect of tenofovir disoproxil fumarate on drug-resistant HBV clones, JOURNAL OF INFECTION, 72(1), 91-102, JAN 2016
  6. A Patient with CTLA-4 Haploinsufficiency Presenting Gastric Cancer, JOURNAL OF CLINICAL IMMUNOLOGY, 36(1), 28-32, JAN 2016
  7. Randomized comparison of daclatasvir plus asunaprevir versus telaprevir plus peginterferon/ribavirin in Japanese hepatitis C virus patients, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(1), 14-22, JAN 2016
  8. Analysis of Hepatitis C Virus Genotype 1b Resistance Variants in Japanese Patients Treated with Paritaprevir-Ritonavir and Ombitasvir, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 60(2), 1106-1113, FEB 2016
  9. Early events in hepatitis B virus infection: From the cell surface to the nucleus, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(2), 302-309, FEB 2016
  10. Elimination of HCV via a non-ISG-mediated mechanism by vaniprevir and BMS-788329 combination therapy in human hepatocyte chimeric mice, VIRUS RESEARCH, 213, 62-68, FEB 2 2016
  11. An Analysis of Surgical Treatment for the Spontaneous Rupture of Hepatocellular Carcinoma, DIGESTIVE SURGERY, 33(1), 43-50, 2016
  12. Regression of Cecal MALT Lymphoma after Antibiotic Treatment in a Patient with Helicobacter pylori Infection, INTERNAL MEDICINE, 55(2), 135-139, 2016
  13. Preoperative Biliary Drainage in Cases of Borderline Resectable Pancreatic Cancer Treated with Neoadjuvant Chemotherapy and Surgery, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2016
  14. Association between variants in the interferon lambda 4 locus and substitutions in the hepatitis C virus non-structural protein 5A, JOURNAL OF HEPATOLOGY, 63(3), 554-563, SEP 2015
  15. Pulverized konjac glucomannan ameliorates oxazolone-induced colitis in mice, EUROPEAN JOURNAL OF NUTRITION, 54(6), 959-969, SEP 2015
  16. Comparison of hepatic arterial infusion chemotherapy versus sorafenib monotherapy in patients with advanced hepatocellular carcinoma, JOURNAL OF DIGESTIVE DISEASES, 16(9), 505-512, SEP 2015
  17. Evaluation of dual-wavelength excitation autofluorescence imaging of colorectal tumours with a high-sensitivity CMOS imager: a cross-sectional study, BMC GASTROENTEROLOGY, 15, SEP 2 2015
  18. Human Cytotoxic T Lymphocyte-Mediated Acute Liver Failure and Rescue by Immunoglobulin in Human Hepatocyte Transplant TK-NOG Mice, JOURNAL OF VIROLOGY, 89(19), 10087-10096, OCT 2015
  19. Rho-Associated Kinase Activity Is an Independent Predictor of Cardiovascular Events in Acute Coronary Syndrome, HYPERTENSION, 66(4), 892-899, OCT 2015
  20. Diagnosis of Helicobacter pylori-induced gastritis by serum pepsinogen levels, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(10), 1473-1477, OCT 2015
  21. Randomized phase 3 trial of ombitasvir/paritaprevir/ritonavir for hepatitis C virus genotype 1b-infected Japanese patients with or without cirrhosis, HEPATOLOGY, 62(4), 1037-1046, OCT 2015
  22. Risk of bleeding after endoscopic submucosal dissection for colorectal tumors in patients with continued use of low-dose aspirin, JOURNAL OF GASTROENTEROLOGY, 50(10), 1041-1046, OCT 2015
  23. Clinical utility of gadoxetate disodium-enhanced hepatic MRI for stereotactic body radiotherapy of hepatocellular carcinoma, JAPANESE JOURNAL OF RADIOLOGY, 33(10), 627-635, OCT 2015
  24. HCV Drug Resistance Challenges in Japan: The Role of Pre-Existing Variants and Emerging Resistant Strains in Direct Acting Antiviral Therapy, VIRUSES-BASEL, 7(10), 5328-5342, OCT 2015
  25. Treatment of hepatic amyloid light-chain amyloidosis with bortezomib and dexamethasone in a liver transplant patient, HEPATOLOGY RESEARCH, 45(10), E150-E155, OCT 2015
  26. Long term persistence of NS5A inhibitor-resistant hepatitis C virus in patients who failed daclatasvir and asunaprevir therapy, JOURNAL OF MEDICAL VIROLOGY, 87(11), 1913-1920, NOV 2015
  27. Usefulness of combining gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging and contrast-enhanced ultrasound for diagnosing the macroscopic classification of small hepatocellular carcinoma, EUROPEAN RADIOLOGY, 25(11), 3272-3281, NOV 2015
  28. A novel noninvasive diagnostic method for nonalcoholic steatohepatitis using two glycobiomarkers, HEPATOLOGY, 62(5), 1433-1443, NOV 2015
  29. Clinical usefulness of endocytoscopy in the remission stage of ulcerative colitis: a pilot study, JOURNAL OF GASTROENTEROLOGY, 50(11), 1087-1093, NOV 2015
  30. Biphasic effect of alcohol intake on the development of fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 50(11), 1114-1123, NOV 2015
  31. Elevation of Serum Levels of Advanced Glycation End Products in Patients With Non-B or Non-C Hepatocellular Carcinoma, JOURNAL OF CLINICAL LABORATORY ANALYSIS, 29(6), 480-484, NOV 2015
  32. Sustained virological response to antiviral therapy improves survival rate in patients with recurrent hepatitis C virus infection after liver transplantation, HEPATOLOGY RESEARCH, 45(11), 1047-1054, NOV 2015
  33. Eicosapentaenoic acid/arachidonic acid ratio as a possible link between non-alcoholic fatty liver disease and cardiovascular disease, HEPATOLOGY RESEARCH, 45(5), 533-539, MAY 2015
  34. Novel Robust in Vitro Hepatitis B Virus Infection Model Using Fresh Human Hepatocytes Isolated from Humanized Mice, AMERICAN JOURNAL OF PATHOLOGY, 185(5), 1275-1285, MAY 2015
  35. Randomized Trial of Interferon- and Ribavirin-Free Ombitasvir/Paritaprevir/Ritonavir in Treatment-Experienced Hepatitis C Virus-Infected Patients, HEPATOLOGY, 61(5), 1523-1532, MAY 2015
  36. Evaluation of Antibiotic Use to Prevent Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Cholangitis, HEPATO-GASTROENTEROLOGY, 62(138), 417-424, MAR-APR 2015
  37. Differences in serum microRNA profiles in hepatitis B and C virus infection, JOURNAL OF INFECTION, 70(3), 273-287, MAR 2015
  38. Emerging treatments for chronic hepatitis C, JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 114(3), 204-215, MAR 2015
  39. The effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(3), 619-627, MAR 2015
  40. Disseminated carcinomatosis of the bone marrow originating from hepatocellular carcinoma. A case report, HEPATOLOGY RESEARCH, 45(6), 705-710, JUN 2015
  41. Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis, HEPATOLOGY RESEARCH, 45(6), 656-662, JUN 2015
  42. Role of 3-D conformal radiotherapy for major portal vein tumor thrombosis combined with hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma, HEPATOLOGY RESEARCH, 45(6), 607-617, JUN 2015
  43. The Time Course of Dynamic Computed Tomographic Appearance of Radiation Injury to the Cirrhotic Liver Following Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma, PLOS ONE, 10(6), JUN 11 2015
  44. High Sustained Virologic Response to Daclatasvir Plus Asunaprevir in Elderly and Cirrhotic Patients with Hepatitis C Virus Genotype 1b Without Baseline NS5A Polymorphisms, ADVANCES IN THERAPY, 32(7), 637-649, JUL 2015
  45. Major predictors of portal hypertensive enteropathy in patients with liver cirrhosis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(1), 124-130, JAN 2015
  46. Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection, EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 9(1), 21-30, JAN 2015
  47. Ratio of Serum Levels of AGEs to Soluble Form of RAGE Is a Predictor of Endothelial Function, DIABETES CARE, 38(1), 119-125, JAN 2015
  48. Towards safer and appropriate application of endoscopic submucosal dissection for T1 colorectal carcinoma as total excisional biopsy: Future perspectives, DIGESTIVE ENDOSCOPY, 27(2), 216-222, JAN 2015
  49. Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity, Nature Communications, 6, JAN 2015
  50. A Computer System To Be Used With Laser-based Endoscopy for Quantitative Diagnosis of Early Gastric Cancer, JOURNAL OF CLINICAL GASTROENTEROLOGY, 49(2), 108-115, FEB 2015
  51. Effect of prolonged administration of pegylated interferon/ribavirin therapy in genotypes 2a and 2b: Propensity score-matched analysis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(2), 337-344, FEB 2015
  52. Emergence of resistant variants detected by ultra-deep sequencing after asunaprevir and daclatasvir combination therapy in patients infected with hepatitis C virus genotype 1, JOURNAL OF VIRAL HEPATITIS, 22(2), 158-165, FEB 2015
  53. mTOR and PDGF Pathway Blockade Inhibits Liver Metastasis of Colorectal Cancer by Modulating the Tumor Microenvironment, AMERICAN JOURNAL OF PATHOLOGY, 185(2), 399-408, FEB 2015
  54. Ribavirin dose reduction during telaprevir/ribavirin/peg-interferon therapy overcomes the effect of the ITPA gene polymorphism, JOURNAL OF VIRAL HEPATITIS, 22(2), 166-174, FEB 2015
  55. The Association between Glyceraldehyde-Derived Advanced Glycation End-Products and Colorectal Cancer Risk, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 24(12), 1855-1863, DEC 2015
  56. Factors associated with the effect of interferon-alpha sequential therapy in order to discontinue nucleoside/nucleotide analog treatment in patients with chronic hepatitis B, HEPATOLOGY RESEARCH, 45(12), 1195-1202, DEC 2015
  57. Interobserver and intraobserver agreement for gastric mucosa atrophy, BMC GASTROENTEROLOGY, 15, AUG 4 2015
  58. Major predictors and management of small-bowel angioectasia, BMC GASTROENTEROLOGY, 15, AUG 25 2015
  59. Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection, SCIENCE TRANSLATIONAL MEDICINE, 7(282), APR 8 2015
  60. Effect of Aldosterone-Producing Adenoma on Endothelial Function and Rho-Associated Kinase Activity in Patients With Primary Aldosteronism, HYPERTENSION, 65(4), 841-848, APR 2015
  61. Evaluation of early response to hepatic arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma using the combination of Response Evaluation Criteria in Solid Tumors and tumor markers, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(4), 726-732, APR 2015
  62. Risk factors and management of positive horizontal margin in early gastric cancer resected by en bloc endoscopic submucosal dissection, GASTRIC CANCER, 18(2), 332-338, APR 2015
  63. Stereotactic body radiotherapy for patients with small hepatocellular carcinoma ineligible for resection or ablation therapies, HEPATOLOGY RESEARCH, 45(4), 378-386, APR 2015
  64. Two Patients Treated With Simeprevir Plus Pegylated-Interferon and Ribavirin Triple Therapy for Recurrent Hepatitis C After Living Donor Liver Transplantation: Case Report, TRANSPLANTATION PROCEEDINGS, 47(3), 809-814, APR 2015
  65. Endoscopic Submucosal Dissection as Total Excisional Biopsy for Clinical T1 Colorectal Carcinoma, DIGESTION, 91(1), 64-69, 2015
  66. On-treatment low serum HBV RNA level predicts initial virological response in chronic hepatitis B patients receiving nucleoside analogue therapy, ANTIVIRAL THERAPY, 20(4), 369-375, 2015
  67. Successful Use of Adalimumab for Treating Pyoderma Gangrenosum with Ulcerative Colitis under Corticosteroid-tapering Conditions, INTERNAL MEDICINE, 54(17), 2167-2172, 2015
  68. Antibiotic prophylaxis for endoscopic retrograde chlangiopancreatography increases the detection rate of drug-resistant bacteria in bile, JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 21(9), 712-718, SEP 2014
  69. Human microRNA hsa-miR-1231 suppresses hepatitis B virus replication by targeting core mRNA, JOURNAL OF VIRAL HEPATITIS, 21(9), E89-E97, SEP 2014
  70. Interleukin 28B polymorphism predicts interferon plus ribavirin treatment outcome in patients with hepatitis C virus-related liver cirrhosis: A multicenter retrospective study in Japan, HEPATOLOGY RESEARCH, 44(9), 983-992, SEP 2014
  71. Critical Role of Exogenous Nitric Oxide in ROCK Activity in Vascular Smooth Muscle Cells, PLOS ONE, 9(10), e109017, OCT 3 2014
  72. Case reports of portal vein thrombosis and bile duct stenosis after stereotactic body radiation therapy for hepatocellular carcinoma, HEPATOLOGY RESEARCH, 44(10), E273-E278, OCT 2014
  73. New Insight Into the Enhanced Effect of Pegylated Interferon-alpha, HEPATOLOGY, 60(4), 1435-1437, OCT 2014
  74. Differences in K-ras and mitochondrial DNA mutations and microsatellite instability between colorectal cancers of Vietnamese and Japanese patients, BMC GASTROENTEROLOGY, 14, NOV 30 2014
  75. Endocannabinoid CB1 antagonists inhibit hepatitis C virus production, providing a novel class of antiviral host-targeting agents, JOURNAL OF GENERAL VIROLOGY, 95, 2468-2479, NOV 2014
  76. Hepatitis C Virus Core Protein Suppresses Mitophagy by Interacting with Parkin in the Context of Mitochondrial Depolarization, AMERICAN JOURNAL OF PATHOLOGY, 184(11), 3026-3039, NOV 2014
  77. Two patients treated with pegylated interferon/ribavirin/telaprevir triple therapy for recurrent hepatitis C after living donor liver transplantation, HEPATOLOGY RESEARCH, 44(12), 1259-1264, NOV 2014
  78. Type 2 diabetes mellitus is associated with the fibrosis severity in patients with nonalcoholic fatty liver disease in a large retrospective cohort of Japanese patients, JOURNAL OF GASTROENTEROLOGY, 49(11), 1477-1484, NOV 2014
  79. Upper limit of normal serum alanine aminotransferase levels in Japanese subjects, HEPATOLOGY RESEARCH, 44(12), 1196-1207, NOV 2014
  80. Effect of vitamin D supplementation on pegylated interferon/ribavirin therapy for chronic hepatitis C genotype 1b: a randomized controlled trial, JOURNAL OF VIRAL HEPATITIS, 21(5), 348-356, MAY 2014
  81. Long-term outcome of patients with gastric varices treated by balloon-occluded retrograde transvenous obliteration, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29(5), 1035-1042, MAY 2014
  82. Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease, JOURNAL OF HUMAN GENETICS, 59(5), 241-246, MAY 2014
  83. Characteristic Features of Cholangiocarcinoma Complicating Primary Sclerosing Cholangitis, HEPATO-GASTROENTEROLOGY, 61(131), 567-573, MAY 2014
  84. Efficacy and Safety of Sitagliptin for the Treatment of Nonalcoholic Fatty Liver Disease with Type 2 Diabetes Mellitus, HEPATO-GASTROENTEROLOGY, 61(130), 323-328, MAR-APR 2014
  85. A comparative study of 4 Fr versus 6 Fr nasobiliary drainage catheters: A randomized, controlled trial, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29(3), 653-659, MAR 2014
  86. Aryl hydrocarbon receptor plays protective roles in ConA-induced hepatic injury by both suppressing IFN- expression and inducing IL-22, INTERNATIONAL IMMUNOLOGY, 26(3), 129-137, MAR 2014
  87. Is It Possible to Discriminate Between Neoplastic and Nonneoplastic Lesions in Ulcerative Colitis by Magnifying Colonoscopy?, INFLAMMATORY BOWEL DISEASES, 20(3), 508-513, MAR 2014
  88. Is small-bowel capsule endoscopy effective for diagnosis of esophagogastric lesions related to portal hypertension?, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29(3), 511-516, MAR 2014
  89. Non-invasive liver fibrosis score calculated by combination of virtual touch tissue quantification and serum liver functional tests in chronic hepatitis C patients, HEPATOLOGY RESEARCH, 44(3), 280-287, MAR 2014
  90. Non-invasive liver fibrosis score calculated by combination of virtual touch tissue quantification and serum liver functional tests in chronic hepatitis C patients, HEPATOLOGY RESEARCH, 44(3), 280-287, MAR 2014
  91. Predictors of incomplete resection and perforation associated with endoscopic submucosal dissection for colorectal tumors, GASTROINTESTINAL ENDOSCOPY, 79(3), 427-435, MAR 2014
  92. Transarterial Therapy of Hepatocellular Carcinoma Fed by the Right Renal Capsular Artery, JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 25(3), 389-395, MAR 2014
  93. Long-Term Elimination of Hepatitis C Virus from Human Hepatocyte Chimeric Mice After Interferon-gamma Gene Transfer, HUMAN GENE THERAPY CLINICAL DEVELOPMENT, 25(1), 28-39, MAR 1 2014
  94. Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system, SCIENTIFIC REPORTS, 4, JUN 23 2014
  95. Daclatasvir Plus Asunaprevir for Chronic HCV Genotype 1b Infection, HEPATOLOGY, 59(6), 2083-2091, JUN 2014
  96. IFNL4/IL-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population, JOURNAL OF GENERAL VIROLOGY, 95, 1297-1306, JUN 2014
  97. Timing of radiological improvement after steroid therapy in patients with autoimmune pancreatitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 49(6), 727-733, JUN 2014
  98. Association of polymorphisms in GCKR and TRIB1 with nonalcoholic fatty liver disease and metabolic syndrome traits, ENDOCRINE JOURNAL, 61(7), 683-689, JUL 2014
  99. Borderline Ankle-Brachial Index Value of 0.91-0.99 Is Associated With Endothelial Dysfunction, CIRCULATION JOURNAL, 78(7), 1740-+, JUL 2014
  100. Continued use of low-dose aspirin does not increase the risk of bleeding during or after endoscopic submucosal dissection for early gastric cancer, GASTRIC CANCER, 17(3), 489-496, JUL 2014
  101. Percutaneous transvenous embolization for portosystemic shunts associated with encephalopathy: Long-term outcomes in 14 patients, HEPATOLOGY RESEARCH, 44(7), 740-749, JUL 2014
  102. Relationship between nitroglycerine-induced vasodilation and clinical severity of peripheral artery disease, ATHEROSCLEROSIS, 235(1), 65-70, JUL 2014
  103. Risk factors for delayed bleeding after endoscopic submucosal dissection for colorectal neoplasms, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 29(7), 877-882, JUL 2014
  104. The association of insomnia with gastroesophageal reflux symptoms in biopsy-proven nonalcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 49(7), 1163-1174, JUL 2014
  105. Pilot Study of Stereotactic Body Radiation Therapy Combined with Transcatheter Arterial Chemoembolization for Small Hepatocellular Carcinoma, HEPATO-GASTROENTEROLOGY, 61(129), 31-36, JAN-FEB 2014
  106. The effect of respiratory-gated positron emission tomography/computed tomography in patients with pancreatic cancer, HELLENIC JOURNAL OF NUCLEAR MEDICINE, 17(1), 31-36, JAN-APR 2014
  107. Advanced Method for Evaluation of Gastric Cancer Risk By Serum Markers: Determination of True Low-Risk Subjects for Gastric Neoplasm, HELICOBACTER, 19(1), 1-8, FEB 2014
  108. Clinical validity of the expanded criteria for endoscopic resection of undifferentiated-type early gastric cancer based on long-term outcomes, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 28(2), 639-647, FEB 2014
  109. Serum asymmetric dimethylarginine levels are independently associated with procollagen III N-terminal peptide in nonalcoholic fatty liver disease patients, CLINICAL AND EXPERIMENTAL MEDICINE, 14(1), 45-51, FEB 2014
  110. Clinical outcome and prognostic factors of patients with hepatocellular carcinoma and extrahepatic metastasis treated with sorafenib, HEPATOLOGY RESEARCH, 44(13), 1320-1328, DEC 2014
  111. Impact of alloimmune T cell responses on hepatitis C virus replication in liver transplant recipients, HUMAN IMMUNOLOGY, 75(12), 1259-1267, DEC 2014
  112. Interferon lambda 4 polymorphism affects on outcome of telaprevir, pegylated interferon and ribavirin combination therapy for chronic hepatitis C, HEPATOLOGY RESEARCH, 44(14), E447-E454, DEC 2014
  113. Non-invasive assessment of liver steatosis in non-alcoholic fatty liver disease, HEPATOLOGY RESEARCH, 44(14), E420-E427, DEC 2014
  114. Predictive value of the IFNL4 polymorphism on outcome of telaprevir, peginterferon, and ribavirin therapy for older patients with genotype 1b chronic hepatitis C, JOURNAL OF GASTROENTEROLOGY, 49(12), 1548-1556, DEC 2014
  115. Quantitative Effect of Natural Killer-Cell Licensing on Hepatocellular Carcinoma Recurrence after Curative Hepatectomy, CANCER IMMUNOLOGY RESEARCH, 2(12), 1142-1147, DEC 2014
  116. Integrated Analysis of Whole Genome and Transcriptome Sequencing Reveals Diverse Transcriptomic Aberrations Driven by Somatic Genomic Changes in Liver Cancers, PLOS ONE, 9(12), DEC 19 2014
  117. Smoking Cessation Reverses DNA Double-Strand Breaks in Human Mononuclear Cells, PLOS ONE, 9(8), AUG 5 2014
  118. Simple scoring system for predicting cirrhosis in nonalcoholic fatty liver disease, WORLD JOURNAL OF GASTROENTEROLOGY, 20(29), 10108-10114, AUG 21 2014
  119. Characteristic Epithelium with Low-Grade Atypia Appears on the Surface of Gastric Cancer after Successful Helicobacter pylori Eradication Therapy, HELICOBACTER, 19(4), 289-295, AUG 2014
  120. Clinical outcomes of endoscopic submucosal dissection for superficial Barrett's adenocarcinoma, GASTROINTESTINAL ENDOSCOPY, 80(2), 239-245, AUG 2014
  121. Clinical efficacy of combination therapy with ME3738 and pegylated interferon-alpha-2a in patients with hepatitis C virus genotype 1, HEPATOLOGY RESEARCH, 44(4), 410-419, APR 2014
  122. Condition of muscularis mucosae is a risk factor for lymph node metastasis in T1 colorectal carcinoma, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 28(4), 1269-1276, APR 2014
  123. Efficacy of probucol for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label pilot study, HEPATOLOGY RESEARCH, 44(4), 429-435, APR 2014
  124. Endoscopic features and management of diminutive colorectal submucosal invasive carcinoma, DIGESTIVE ENDOSCOPY, 26, 78-83, APR 2014
  125. Nonalcoholic Fatty Liver Disease and Cardiovascular Disease, CURRENT PHARMACEUTICAL DESIGN, 20(14), 2403-2411, APR 2014
  126. Poor Oral Health, That Is, Decreased Frequency of Tooth Brushing, Is Associated With Endothelial Dysfunction, CIRCULATION JOURNAL, 78(4), 950-954, APR 2014
  127. Rho-Associated Kinase Activity Is a Predictor of Cardiovascular Outcomes, HYPERTENSION, 63(4), 856-864, APR 2014
  128. Ultradeep Sequencing Study of Chronic Hepatitis C Virus Genotype 1 Infection in Patients Treated with Daclatasvir, Peginterferon, and Ribavirin, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 58(4), 2105-2112, APR 2014
  129. Efficacy of telaprevir-based therapy for difficult-to-treat patients with genotype 2 chronic hepatitis C in Japan, HEPATOLOGY RESEARCH, 45(7), 745-754, 20140901
  130. A MAVS/TICAM-1-Independent Interferon-Inducing Pathway Contributes to Regulation of Hepatitis B Virus Replication in the Mouse Hydrodynamic Injection Model., J Innate Immun., 20140801
  131. Detection of nonpolypoid colorectal neoplasia using magnifying endoscopy in colonic inflammatory bowel disease., Gastrointest Endosc Clin N Am., 24(3), 405-17, 20140701
  132. IFNL4 polymorphism affects on outcome of telaprevir, peg-interferon and ribavirin combination therapy for chronic hepatitis C., Hepatol Res., 20140401
  133. On-treatment low serum HBV RNA level predicts initial virological response in chronic hepatitis B patients receiving nucleoside analogue therapy., Antivir Ther., 20140401
  134. Efficacy and safety of sitagliptin for the treatment of nonalcoholic fatty liver disease with type 2 diabetes mellitus., Hepatogastroenterology., 61(130), 323-328, 20140301
  135. Letter: Pitavastatin supplementation of PEG-IFN/ribavirin improves sustained virological response against HCV, Aliment Pharmacol Ther., 39(4), 443-4, 20140201
  136. Serum interleukin-6 associated with hepatocellular carcinoma risk: a nested case-control study, Int J Cancer, 134(1), 154-163, 20140101
  137. Ultra deep sequencing study of HCV genotype 1 in chronic hepatitis patients treated with daclatasvir, peg-interferon and ribavirin, Antimicrob Agents Chemother, 20140101
  138. A randomized trial of daclatasvir with peginterferon alfa-2b and ribavirin for HCV genotype 1 infection, ANTIVIRAL THERAPY, 19(5), 491-499, 2014
  139. Characteristics of Metachronous Gastric Tumors after Endoscopic Submucosal Dissection for Gastric Intraepithelial Neoplasms, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2014
  140. Comparison of Small-Bowel Mucosal Injury between Low-Dose Aspirin and Non-Aspirin Non-Steroidal Anti-Inflammatory Drugs: A Capsule Endoscopy Study, DIGESTION, 89(3), 225-231, 2014
  141. Hepatitis C Virus (HCV) Reactivation Caused by Steroid Therapy for Dermatomyositis, INTERNAL MEDICINE, 53(23), 2689-2693, 2014
  142. Occupational Radiation Exposure during Endoscopic Retrograde Cholangiopancreatography and Usefulness of Radiation Protective Curtains, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2014
  143. Telaprevir is effective given every 12 h at 750 mg with pegylated interferon-alpha 2b and ribavirin to Japanese patients with HCV-1b IL28B rs8099917 TT, ANTIVIRAL THERAPY, 19(3), 277-285, 2014
  144. Virological escape in HCV genotype-1-infected patients receiving daclatasvir plus ribavirin and peginterferon alfa-2a or alfa-2b, ANTIVIRAL THERAPY, 19(5), 479-490, 2014
  145. A Translational Study of Resistance Emergence Using Sequential Direct-Acting Antiviral Agents for Hepatitis C Using Ultra-Deep Sequencing, AMERICAN JOURNAL OF GASTROENTEROLOGY, 108(9), 1464-1472, SEP 2013
  146. Clinical usefulness of classification by transabdominal ultrasonography for detection of small-bowel stricture, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 48(9), 1041-1047, SEP 2013
  147. Noninvasive scoring systems in patients with nonalcoholic fatty liver disease with normal alanine aminotransferase levels, JOURNAL OF GASTROENTEROLOGY, 48(9), 1051-1060, SEP 2013
  148. Risk factors for vertical incomplete resection in endoscopic submucosal dissection as total excisional biopsy for submucosal invasive colorectal carcinoma, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 28(9), 1247-1256, SEP 2013
  149. Thromboxane A(2) Synthase Inhibitors Prevent Production of Infectious Hepatitis C Virus in Mice With Humanized Livers, GASTROENTEROLOGY, 145(3), 658-+, SEP 2013
  150. Clinical outcomes of endoscopic submucosal dissection for early gastric cancer in patients with chronic kidney disease, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(10), 1632-1637, OCT 2013
  151. Elevated expression of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 in primary sclerosing cholangitis: Implications for cholangiocarcinogenesis, INTERNATIONAL JOURNAL OF ONCOLOGY, 43(4), 1073-1079, OCT 2013
  152. Serum HBV RNA and HBeAg are useful markers for the safe discontinuation of nucleotide analogue treatments in chronic hepatitis B patients, JOURNAL OF GASTROENTEROLOGY, 48(10), 1188-1204, OCT 2013
  153. A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 441(1), 230-235, NOV 8 2013
  154. Glycemic Variability Is an Independent Predictive Factor for Development of Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease, PLOS ONE, 8(11), NOV 6 2013
  155. Clinicopathologic features of hyperplastic/serrated polyposis syndrome in Japan, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(11), 1693-1698, NOV 2013
  156. Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice, JOURNAL OF GASTROENTEROLOGY, 48(11), 1259-1270, NOV 2013
  157. Utility of controlled attenuation parameter measurement for assessing liver steatosis in Japanese patients with chronic liver diseases, HEPATOLOGY RESEARCH, 43(11), 1182-1189, NOV 2013
  158. Genetic Analyses Reveal a Role for Vitamin D Insufficiency in HCV-Associated Hepatocellular Carcinoma Development, PLOS ONE, 8(5), MAY 29 2013
  159. A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region, JOURNAL OF HEPATOLOGY, 58(5), 875-882, MAY 2013
  160. Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B, JOURNAL OF MEDICAL VIROLOGY, 85(5), 789-798, MAY 2013
  161. Left atrial thickness under the catheter ablation lines in patients with paroxysmal atrial fibrillation: insights from 64-slice multidetector computed tomography, HEART AND VESSELS, 28(3), 360-368, MAY 2013
  162. Quantitative identification of mucosal gastric cancer under magnifying endoscopy with flexible spectral imaging color enhancement, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(5), 841-847, MAY 2013
  163. Risk analysis of submucosal invasive rectal carcinomas for lymph node metastasis to expand indication criteria for endoscopic resection, DIGESTIVE ENDOSCOPY, 25, 21-25, MAY 2013
  164. Small Bowel Abnormalities in Patients with Compensated Liver Cirrhosis, DIGESTIVE DISEASES AND SCIENCES, 58(5), 1390-1396, MAY 2013
  165. High Expression of Gastrin Receptor Protein in Injured Mucosa of Helicobacter pylori-Positive Gastritis, DIGESTIVE DISEASES AND SCIENCES, 58(3), 634-640, MAR 2013
  166. Inhibition of hepatocellular carcinoma by PegIFN alpha-2a in patients with chronic hepatitis C: a nationwide multicenter cooperative study, JOURNAL OF GASTROENTEROLOGY, 48(3), 382-390, MAR 2013
  167. Involvement of microRNA-224 in cell proliferation, migration, invasion, and anti-apoptosis in hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(3), 565-575, MAR 2013
  168. Stereotactic body radiation therapy combined with transcatheter arterial chemoembolization for small hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(3), 530-536, MAR 2013
  169. Surgical treatment for portosystemic encephalopathy in patients with liver cirrhosis: Occlusion of portosystemic shunt in combination with splenectomy, HEPATOLOGY RESEARCH, 43(3), 249-254, MAR 2013
  170. Virological response and safety of 24-week telaprevir alone in Japanese patients infected with hepatitis C virus subtype 1b, JOURNAL OF VIRAL HEPATITIS, 20(3), 167-173, MAR 2013
  171. Warning for unprincipled colorectal endoscopic submucosal dissection: Accurate diagnosis and reasonable treatment strategy, DIGESTIVE ENDOSCOPY, 25(2), 107-116, MAR 2013
  172. Nitroglycerine-Induced Vasodilation for Assessment of Vascular Function A Comparison With Flow-Mediated Vasodilation, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 33(6), 1401-+, JUN 2013
  173. Autologous Bone-Marrow Mesenchymal Stem Cell Implantation and Endothelial Function in a Rabbit Ischemic Limb Model, PLOS ONE, 8(7), JUL 4 2013
  174. Effectiveness of polaprezinc for low-dose aspirin-induced small-bowel mucosal injuries as evaluated by capsule endoscopy: a pilot randomized controlled study, BMC GASTROENTEROLOGY, 13, JUL 4 2013
  175. Combination therapies with NS5A, NS3 and NS5B inhibitors on different genotypes of hepatitis C virus in human hepatocyte chimeric mice, GUT, 62(7), 1055-1061, JUL 2013
  176. Dynamic computed tomography appearance of tumor response after stereotactic body radiation therapy for hepatocellular carcinoma: How should we evaluate treatment effects?, HEPATOLOGY RESEARCH, 43(7), 717-727, JUL 2013
  177. Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan, HUMAN GENETICS, 132(7), 783-792, JUL 2013
  178. Outcome of endoscopic submucosal dissection for gastric neoplasm in relationship to endoscopic classification of submucosal fibrosis, GASTRIC CANCER, 16(3), 404-410, JUL 2013
  179. Risk factors for the exacerbation of esophageal varices or portosystemic encephalopathy after sustained virological response with IFN therapy for HCV-related compensated cirrhosis, JOURNAL OF GASTROENTEROLOGY, 48(7), 847-855, JUL 2013
  180. Interleukin-28B polymorphisms and hepatitis C virus clearance, GENOME MEDICINE, 5, JAN 29 2013
  181. Single-nucleotide polymorphisms in GALNT8 are associated with the response to interferon therapy for chronic hepatitis C, JOURNAL OF GENERAL VIROLOGY, 94, 81-89, JAN 2013
  182. Treatment of chronic hepatitis C virus infection in Japan: update on therapy and guidelines, JOURNAL OF GASTROENTEROLOGY, 48(1), 1-12, JAN 2013
  183. Endoscopic submucosal dissection for residual early gastric cancer after endoscopic submucosal dissection, GASTROINTESTINAL ENDOSCOPY, 77(2), 298-302, FEB 2013
  184. Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer, INTERNATIONAL JOURNAL OF CANCER, 132(4), 813-823, FEB 15 2013
  185. Clinical outcome of sorafenib treatment in patients with advanced hepatocellular carcinoma refractory to hepatic arterial infusion chemotherapy, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(12), 1834-1841, DEC 2013
  186. Combining Molecular Targeted Drugs to Inhibit Both Cancer Cells and Activated Stromal Cells in Gastric Cancer, NEOPLASIA, 15(12), 1391-1399, DEC 2013
  187. sRAGE is associated with low waist circumference and Hb levels in NAFLD, CENTRAL EUROPEAN JOURNAL OF MEDICINE, 8(6), 830-834, DEC 2013
  188. HLA-DQB1*03 Confers Susceptibility to Chronic Hepatitis C in Japanese: A Genome-Wide Association Study, PLOS ONE, 8(12), DEC 20 2013
  189. Relationship between flow-mediated vasodilation and cardiovascular risk factors in a large community-based study, HEART, 99(24), 1837-1842, DEC 15 2013
  190. Inferior vena cava tumor thrombus that directly infiltrated from paracaval lymph node metastases in a patient with recurrent hepatocellular carcinoma, WORLD JOURNAL OF SURGICAL ONCOLOGY, 11, AUG 6 2013
  191. A novel noninvasive and simple method for assessment of endothelial function: Enclosed zone flow-mediated vasodilation (ezFMD) using an oscillation amplitude measurement, ATHEROSCLEROSIS, 229(2), 324-330, AUG 2013
  192. NUDT3 rs206936 is associated with body mass index in obese Japanese women, ENDOCRINE JOURNAL, 60(8), 991-1000, AUG 2013
  193. A Nonsynonymous Polymorphism in Semaphorin 3A as a Risk Factor for Human Unexplained Cardiac Arrest with Documented Ventricular Fibrillation, PLOS GENETICS, 9(4), APR 2013
  194. Airway Stenting for Tracheal Obstruction Due to Lymph Node Metastasis of Hepatocellular Carcinoma, ANTICANCER RESEARCH, 33(4), 1761-1764, APR 2013
  195. Characteristic magnifying narrow-band imaging features of colorectal tumors in each growth type, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 28(4), 459-468, APR 2013
  196. Characterization of virologic escape in hepatitis C virus genotype 1b patients treated with the direct-acting antivirals daclatasvir and asunaprevir, JOURNAL OF HEPATOLOGY, 58(4), 646-654, APR 2013
  197. Dual oral therapy with daclatasvir and asunaprevir for patients with HCV genotype 1b infection and limited treatment options, JOURNAL OF HEPATOLOGY, 58(4), 655-662, APR 2013
  198. Flow-Mediated Vasodilation and Anatomical Variation of the Brachial Artery (Double Brachial Artery) in Healthy Subjects and Patients With Cardiovascular Disease, CIRCULATION JOURNAL, 77(4), 1073-1080, APR 2013
  199. Identification of a Functional Variant in the MICA Promoter Which Regulates MICA Expression and Increases HCV-Related Hepatocellular Carcinoma Risk, PLOS ONE, 8(4), APR 11 2013
  200. The long-term outcome of patients with gastric varices treated by balloon-occluded retrograde transvenous obliteration, J Gastroenterol Hepatol, 29(5), 1035-1042, 20131201
  201. The upper limit of normal serum alanine aminotransferase levels in Japanese subjects, Hepatol Res, 20131201
  202. Availability of monitoring serum HBV DNA plus RNA during nucleot(s)ide analogue therapy, J Gastroenterol, 48(6), 779-780, 20130601
  203. Response., Gastrointest Endosc., 77, 973-974, 20130601
  204. Endoscopic assessment of colorectal cancer with superficial or deep submucosal invasion using magnifying colonoscopy., Clin Endosc., 46, 138-146, 20130301
  205. Response to "Treatment guidelines for HCV genotype 1: mono for low, triple for high, and dual for 'middle'?"., J Gastroenterol., 20130201
  206. Clinical Characteristics of Patients who Developed Hepatocellular Carcinoma after Hepatitis C Virus Eradication with Interferon Therapy: Current Status in Japan, INTERNAL MEDICINE, 52(24), 2701-2706, 2013
  207. Hyperuricemia is independently associated with endothelial dysfunction in postmenopausal women but not in premenopausal women, BMJ OPEN, 3(11), 2013
  208. Hypovascular Hepatic Nodules Showing Hypointense on the Hepatobiliary-Phase Image of Gd-EOB-DTPA-Enhanced MRI to Develop a Hypervascular Hepatocellular Carcinoma: A Nationwide Retrospective Study on Their Natural Course and Risk Factors, DIGESTIVE DISEASES, 31(5-6), 472-479, 2013
  209. Is Occult Obscure Gastrointestinal Bleeding a Definite Indication for Capsule Endoscopy? A Retrospective Analysis of Diagnostic Yield in Patients with Occult versus Overt Bleeding, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2013
  210. Relationship between Narrow-Band Imaging Magnifying Observation and Pit Pattern Diagnosis in Colorectal Tumors, DIGESTION, 87(1), 53-58, 2013
  211. Replication Study of 15 Recently Published Loci for Body Fat Distribution in the Japanese Population, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 20(4), 336-350, 2013
  212. Impact of interleukin-28B genotype on in vitro and in vivo systems of hepatitis C virus replication, HEPATOLOGY RESEARCH, 42(9), 841-853, SEP 2012
  213. Interleukin-28B single nucleotide polymorphism of donors and recipients can predict viral response to pegylated interferon/ribavirin therapy in patients with recurrent hepatitis C after living donor liver transplantation, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(9), 1467-1472, SEP 2012
  214. Intima-Media Thickness of Brachial Artery, Vascular Function, and Cardiovascular Risk Factors, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(9), 2295-+, SEP 2012
  215. A randomized phase II trial of intra-arterial chemotherapy using SM-11355 (Miriplatin) for hepatocellular carcinoma, INVESTIGATIONAL NEW DRUGS, 30(5), 2015-2025, OCT 2012
  216. Hepatitis B Virus-Specific miRNAs and Argonaute2 Play a Role in the Viral Life Cycle, PLOS ONE, 7(10), OCT 16 2012
  217. Bile Acid Promotes Intestinal Metaplasia and Gastric Carcinogenesis, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 21(11), 2101-2107, NOV 2012
  218. Efficacy of rosuvastatin for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label, pilot study, HEPATOLOGY RESEARCH, 42(11), 1065-1072, NOV 2012
  219. Increased insulinogenic index is an independent determinant of nonalcoholic fatty liver disease activity score in patients with normal glucose tolerance, DIGESTIVE AND LIVER DISEASE, 44(11), 935-939, NOV 2012
  220. Safety and Feasibility of Diet-Treated Donors With Steatotic Livers at the Initial Consultation for Living-Donor Liver Transplantation, TRANSPLANTATION, 93(10), 1024-1030, MAY 27 2012
  221. A huge metastatic liver tumor from leiomyosarcoma of the inferior vena cava: report of a case, SURGERY TODAY, 42(5), 505-508, MAY 2012
  222. Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography, JOURNAL OF HUMAN GENETICS, 57(5), 305-310, MAY 2012
  223. Association of two polymorphisms of the IL28B gene with viral factors and treatment response in 1,518 patients infected with hepatitis C virus, JOURNAL OF GASTROENTEROLOGY, 47(5), 596-605, MAY 2012
  224. CURRENT STATUS AND FUTURE PERSPECTIVES OF ENDOSCOPIC SUBMUCOSAL DISSECTION FOR COLORECTAL TUMORS, DIGESTIVE ENDOSCOPY, 24, 73-79, MAY 2012
  225. Hepatic arterial infusion chemotherapy using 5-fluorouracil and systemic interferon-a for advanced hepatocellular carcinoma in combination with or without three-dimensional conformal radiotherapy to venous tumor thrombosis in hepatic vein or inferior vena cava, HEPATOLOGY RESEARCH, 42(5), 442-453, MAY 2012
  226. Hepatocellular carcinoma: Towards personalized medicine, CANCER SCIENCE, 103(5), 846-850, MAY 2012
  227. Prevalence and associated metabolic factors of nonalcoholic fatty liver disease in the general population from 2009 to 2010 in Japan: a multicenter large retrospective study, JOURNAL OF GASTROENTEROLOGY, 47(5), 586-595, MAY 2012
  228. USEFULNESS AND SAFETY OF SB KNIFE JR IN ENDOSCOPIC SUBMUCOSAL DISSECTION FOR COLORECTAL TUMORS, DIGESTIVE ENDOSCOPY, 24, 90-95, MAY 2012
  229. Value of Cytodiagnosis Using Endoscopic Nasopancreatic Drainage for Early Diagnosis of Pancreatic Cancer Establishing a New Method for the Early Detection of Pancreatic Carcinoma In Situ, PANCREAS, 41(4), 523-529, MAY 2012
  230. A Genome-Wide Association Study of Nephrolithiasis in the Japanese Population Identifies Novel Susceptible Loci at 5q35.3, 7p14.3, and 13q14.1, PLOS GENETICS, 8(3), MAR 2012
  231. Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders, HEPATOLOGY, 55(3), 742-748, MAR 2012
  232. Serum screening for detection of high-risk group for early-stage diffuse type gastric cancer in Japanese, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(3), 598-602, MAR 2012
  233. Treatment of chronic hepatitis B with nucleos(t)ide analogues, HEPATOLOGY RESEARCH, 42(3), 219-225, MAR 2012
  234. Effect of urine pH changed by dietary intervention on uric acid clearance mechanism of pH-dependent excretion of urinary uric acid, NUTRITION JOURNAL, 11, JUN 7 2012
  235. Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-alpha-lowering property, DIGESTIVE AND LIVER DISEASE, 44(6), 492-496, JUN 2012
  236. Diagnostic Yield of Capsule Endoscopy vs. Double-Balloon Endoscopy for Patients who have Undergone Total Enteroscopy with Obscure Gastrointestinal Bleeding, HEPATO-GASTROENTEROLOGY, 59(116), 955-959, JUN 2012
  237. Management of T1 colorectal carcinoma with special reference to criteria for curative endoscopic resection, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(6), 1057-1062, JUN 2012
  238. Hyperbilirubinemia, Augmentation of Endothelial Function, and Decrease in Oxidative Stress in Gilbert Syndrome, CIRCULATION, 126(5), 598-603, JUL 31 2012
  239. Follow up of the 987 blood donors found with hepatitis C virus infection over 9-18 years, HEPATOLOGY RESEARCH, 42(7), 637-647, JUL 2012
  240. Genetics of IL28B and HCV-response to infection and treatment, NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 9(7), 406-417, JUL 2012
  241. IL28B polymorphism is associated with fatty change in the liver of chronic hepatitis C patients, JOURNAL OF GASTROENTEROLOGY, 47(7), 834-844, JUL 2012
  242. Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators, NATURE GENETICS, 44(7), 760-U182, JUL 2012
  243. Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population, BMC GASTROENTEROLOGY, 12, JAN 5 2012
  244. Clinical validity of endoscopic submucosal dissection for submucosal invasive gastric cancer: a single-center study, GASTRIC CANCER, 15(1), 97-105, JAN 2012
  245. Computer-aided system for predicting the histology of colorectal tumors by using narrow-band imaging magnifying colonoscopy, GASTROINTESTINAL ENDOSCOPY, 75(1), 179-185, JAN 2012
  246. Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women, JOURNAL OF HUMAN GENETICS, 57(1), 46-51, JAN 2012
  247. Geranylgeranylacetone, Heat Shock Protein 90/AMP-Activated Protein Kinase/Endothelial Nitric Oxide Synthase/Nitric Oxide Pathway, and Endothelial Function in Humans, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(1), 153-U350, JAN 2012
  248. Role of Natural Killer T Cells in the Mouse Colitis-Associated Colon Cancer Model, SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 75(1), 16-26, JAN 2012
  249. Telaprevir with peginterferon and ribavirin for treatment-naive patients chronically infected with HCV of genotype 1 in Japan, JOURNAL OF HEPATOLOGY, 56(1), 78-84, JAN 2012
  250. Toward the Establishment of a Prediction System for the Personalized Treatment of Chronic Hepatitis C, JOURNAL OF INFECTIOUS DISEASES, 205(2), 204-210, JAN 15 2012
  251. Outcome of patients who have undergone total enteroscopy for obscure gastrointestinal bleeding, WORLD JOURNAL OF GASTROENTEROLOGY, 18(7), 666-672, FEB 21 2012
  252. Combination of hepatitis B viral antigens and DNA for prediction of relapse after discontinuation of nucleos(t)ide analogs in patients with chronic hepatitis B, HEPATOLOGY RESEARCH, 42(2), 139-149, FEB 2012
  253. Efficacy and safety of telaprevir, a new protease inhibitor, for difficult-to-treat patients with genotype 1 chronic hepatitis C, JOURNAL OF VIRAL HEPATITIS, 19(2), E134-E142, FEB 2012
  254. Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor, NATURE MEDICINE, 18(2), 281-285, FEB 2012
  255. Impact of Pegylated Interferon Therapy on Outcomes of Patients with Hepatitis C Virus-Related Hepatocellular Carcinoma After Curative Hepatic Resection, ANNALS OF SURGICAL ONCOLOGY, 19(2), 418-425, FEB 2012
  256. Mineralocorticoid Receptor Blocker Eplerenone Improves Endothelial Function and Inhibits Rho-Associated Kinase Activity in Patients With Hypertension, CLINICAL PHARMACOLOGY & THERAPEUTICS, 91(2), 289-297, FEB 2012
  257. Serum PAI-1 is a novel predictor for response to pegylated interferon-a-2b plus ribavirin therapy in chronic hepatitis C virus infection, JOURNAL OF VIRAL HEPATITIS, 19(2), E126-E133, FEB 2012
  258. Chronic hepatitis B in patients coinfected with human immunodeficiency virus in Japan: a retrospective multicenter analysis, JOURNAL OF INFECTION AND CHEMOTHERAPY, 18(6), 883-890, DEC 2012
  259. Clinical features of pharyngeal intraepithelial neoplasias and outcomes of treatment by endoscopic submucosal dissection, GASTROINTESTINAL ENDOSCOPY, 76(6), 1095-1103, DEC 2012
  260. Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma according to Child-Pugh classification, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(12), 1850-1857, DEC 2012
  261. Serum levels of pigment epithelium-derived factor (PEDF) are independently associated with procollagen III N-terminal peptide levels in patients with nonalcoholic fatty liver disease, CLINICAL BIOCHEMISTRY, 45(18), 1554-1557, DEC 2012
  262. Clinical outcomes of endoscopic submucosal dissection for rectal tumor close to the dentate line, GASTROINTESTINAL ENDOSCOPY, 76(2), 444-450, AUG 2012
  263. Severe necroinflammatory reaction caused by natural killer cell-mediated Fas/Fas ligand interaction and dendritic cells in human hepatocyte chimeric mouse, HEPATOLOGY, 56(2), 555-566, AUG 2012
  264. Clinical outcomes of endoscopic submucosal dissection and endoscopic mucosal resection for laterally spreading tumors larger than 20 mm, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(4), 734-740, APR 2012
  265. Microvascular structure and perfusion imaging of colon cancer by means of contrast-enhanced ultrasonography, ABDOMINAL IMAGING, 37(2), 297-303, APR 2012
  266. Recent trend of clinical features in patients with hepatocellular carcinoma, HEPATOLOGY RESEARCH, 42(4), 368-375, APR 2012
  267. Migration to the pulmonary artery of nine metallic coils placed in the internal iliac vein for treatment of giant rectal varices., Acta Radiol, 1(6), 20120701
  268. Long-Term Outcomes of Hepatic Arterial Port Implantation using a Coaxial Microcatheter System in 176 Patients with Hepatocellular Carcinoma., 61(1), 7-13, 20120301
  269. Compliance with standard precautions among gastrointestinal endoscopists and endoscopy nurses in Japan., Am J Infect Control., 40, 80, 20120201
  270. Regression of rectal MALT lymphoma after antibiotic treatment in a patient negative for Helicobacter pylori, Clin J Gastroenterol, 5(1), 59-63, 20120201
  271. Removal of a sewing needle penetrating the wall of the third portion of the duodenum by double- balloon endoscopy, Clin J Gastroenterol, 5(1), 79-81, 20120201
  272. Change in malpractice claims in Japanese gastroenterological practice, Am J Gastroenterol, 107(1), 143-144, 20120101
  273. Achievement of Sustained Viral Response after Switching Treatment from Pegylated Interferon alpha-2b to alpha-2a and Ribavirin in Patients with Recurrence of Hepatitis C Virus Genotype 1 Infection after Liver Transplantation: A Case Report, INTERVIROLOGY, 55(4), 306-310, 2012
  274. Amino Acid Substitution in HCV Core Region and Genetic Variation near the IL28B Gene Affect Viral Dynamics during Telaprevir, Peginterferon and Ribavirin Treatment, INTERVIROLOGY, 55(6), 417-425, 2012
  275. Amino Acid Substitution in HCV Core/NS5A Region and Genetic Variation Near IL28B Gene Affect Treatment Efficacy to Interferon plus Ribavirin Combination Therapy, INTERVIROLOGY, 55(3), 231-241, 2012
  276. Evaluation of Individual Risk in Nonvariceal Gastrointestinal Bleeding Patients with NSAID Administration: A Multicenter Study in Japan, DIGESTION, 86(3), 187-193, 2012
  277. Evaluation of the mRECIST and alpha-Fetoprotein Ratio for Stratification of the Prognosis of Advanced-Hepatocellular-Carcinoma Patients Treated with Sorafenib, ONCOLOGY, 83(4), 192-200, 2012
  278. Gastric Cancer Development after Helicobacter pylori Eradication Therapy: A New Form of Gastric Neoplasia, DIGESTION, 85(1), 61-67, 2012
  279. Identification of novel HCV deletion mutants in chronic hepatitis C patients, ANTIVIRAL THERAPY, 17(8), 1551-1561, 2012
  280. Helicobacter pylori cagA polymorphism and gastric inflammation: An international comparison between Japanese and Brazilian patients, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 46(9), 1051-1056, SEP 2011
  281. Impact of Viral Amino Acid Substitutions and Host Interleukin-28B Polymorphism on Replication and Susceptibility to Interferon of Hepatitis C Virus, HEPATOLOGY, 54(3), 764-771, SEP 2011
  282. Improved detectability of small-bowel lesions via capsule endoscopy with computed virtual chromoendoscopy: A pilot study, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 46(9), 1133-1137, SEP 2011
  283. Inverse Association of IL28B Genotype and Liver mRNA Expression of Genes Promoting or Suppressing Antiviral State, JOURNAL OF MEDICAL VIROLOGY, 83(9), 1597-1607, SEP 2011
  284. Rapid Emergence of Telaprevir Resistant Hepatitis C Virus Strain from Wildtype Clone In Vivo, HEPATOLOGY, 54(3), 781-788, SEP 2011
  285. Statins induce apoptosis and inhibit proliferation in cholangiocarcinoma cells, INTERNATIONAL JOURNAL OF ONCOLOGY, 39(3), 561-568, SEP 2011
  286. Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area, JOURNAL OF HUMAN GENETICS, 56(10), 716-719, OCT 2011
  287. Frequent somatic mutations of mitochondrial DNA in traditional serrated adenomas but not in sessile serrated adenomas of the colorectum, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 26(10), 1565-1569, OCT 2011
  288. IL28B polymorphism may guide pegylated interferon plus ribavirin therapy even after curative treatment for hepatitis C virus-related hepatocellular carcinoma, JOURNAL OF VIRAL HEPATITIS, 18(10), E550-E560, OCT 2011
  289. Lymphocyte subset characterization associated with persistent hepatitis C virus infection and subsequent progression of liver fibrosis, HUMAN IMMUNOLOGY, 72(10), 821-826, OCT 2011
  290. Prevention of hepatitis B virus reactivation in immunosuppressive therapy or chemotherapy, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 15(5), 634-640, OCT 2011
  291. Rho-Associated Kinase Activity, Endothelial Function, and Cardiovascular Risk Factors, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 31(10), 2353-2359, OCT 2011
  292. RISK FACTORS FOR BLEEDING AFTER ENDOSCOPIC SUBMUCOSAL DISSECTION OF GASTRIC EPITHELIAL NEOPLASM, DIGESTIVE ENDOSCOPY, 23(4), 290-295, OCT 2011
  293. A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population, HUMAN MOLECULAR GENETICS, 20(19), 3884-3892, OCT 1 2011
  294. Assessment of Trypsinogen-2 Levels as an Early Diagnostic for Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis, PANCREAS, 40(8), 1206-1210, NOV 2011
  295. Clinical outcome of esophageal varices after hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with major portal vein tumor thrombus, HEPATOLOGY RESEARCH, 41(11), 1046-1056, NOV 2011
  296. Eradication of hepatitis C virus genotype 1 after liver transplantation by interferon therapy before surgery: Report of three patients with analysis of interleukin-28 polymorphism, hepatitis C virus core region and interferon-sensitivity determining region, HEPATOLOGY RESEARCH, 41(11), 1126-1131, NOV 2011
  297. Platelet count for predicting fibrosis in nonalcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 46(11), 1300-1306, NOV 2011
  298. The Water-Soluble Extract from Cultured Medium of Ganoderma lucidum (Reishi) Mycelia (Designated as MAK) Ameliorates Murine Colitis Induced by Trinitrobenzene Sulphonic Acid, SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 74(5), 454-462, NOV 2011
  299. CLINICAL USEFULNESS OF NARROW BAND IMAGING MAGNIFYING CLASSIFICATION FOR COLORECTAL TUMORS BASED ON BOTH SURFACE PATTERN AND MICROVESSEL FEATURES, DIGESTIVE ENDOSCOPY, 23, 101-105, MAY 2011
  300. Elimination of hepatitis C virus by short term NS3-4A and NS5B inhibitor combination therapy in human hepatocyte chimeric mice, JOURNAL OF HEPATOLOGY, 54(5), 872-878, MAY 2011
  301. IL-28B predicts response to chronic hepatitis C therapy - fine-mapping and replication study in Asian populations, JOURNAL OF GENERAL VIROLOGY, 92, 1071-1081, MAY 2011
  302. Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model, INTERNATIONAL JOURNAL OF CANCER, 128(9), 2050-2062, MAY 1 2011
  303. Plaunotol Induces a Comparative Increase of Acidic Mucin Fraction in Gastric Juice, HEPATO-GASTROENTEROLOGY, 58(106), 663-668, MAR-APR 2011
  304. Prevalence and impact of musculoskeletal pain in Japanese gastrointestinal endoscopists: A controlled study, WORLD JOURNAL OF GASTROENTEROLOGY, 17(11), 1488-1493, MAR 21 2011
  305. Impaired gastric response to modified sham feeding in patients with postprandial distress syndrome, NEUROGASTROENTEROLOGY AND MOTILITY, 23(3), MAR 2011
  306. Possibility of Adoptive Immunotherapy With Peripheral Blood-derived CD3(-)CD56(+) and CD3(+)CD56(+) Cells for Inducing Antihepatocellular Carcinoma and Antihepatitis C Virus Activity, JOURNAL OF IMMUNOTHERAPY, 34(2), 137-146, MAR 2011
  307. Postprandial insulin secretion pattern is associated with histological severity in non-alcoholic fatty liver disease patients without prior known diabetes mellitus, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 26(3), 517-522, MAR 2011
  308. Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b, JOURNAL OF HEPATOLOGY, 54(3), 408-414, MAR 2011
  309. Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model, JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 48(2), 161-166, MAR 2 2011
  310. Clinical features and prognosis in patients with hepatocellular carcinoma that developed after hepatitis C virus eradication with interferon therapy, JOURNAL OF GASTROENTEROLOGY, 46(6), 799-808, JUN 2011
  311. Common Genetic Polymorphism of ITPA Gene Affects Ribavirin-Induced Anemia and Effect of Peg-Interferon Plus Ribavirin Therapy, JOURNAL OF MEDICAL VIROLOGY, 83(6), 1048-1057, JUN 2011
  312. Cutaneous complications after transcatheter arterial treatment for hepatocellular carcinoma via the internal mammary artery: how to avoid this complication, JAPANESE JOURNAL OF RADIOLOGY, 29(5), 307-315, JUN 2011
  313. IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy, JOURNAL OF HEPATOLOGY, 54(6), 1094-1101, JUN 2011
  314. Prediction of Response to Peginterferon-Alfa-2b Plus Ribavirin Therapy in Japanese Patients Infected With Hepatitis C Virus Genotype 1b, JOURNAL OF MEDICAL VIROLOGY, 83(6), 981-988, JUN 2011
  315. Antiviral effects of peginterferon alpha-2b and ribavirin following 24-week monotherapy of telaprevir in Japanese hepatitis C patients, JOURNAL OF GASTROENTEROLOGY, 46(7), 929-937, JUL 2011
  316. Impact of ribavirin dose reduction on the efficacy of pegylated interferon plus ribavirin combination therapy for elderly patients infected with genotype 1b and high viral loads, HEPATOLOGY RESEARCH, 41(7), 626-634, JUL 2011
  317. ME3738 enhances the effect of interferon and inhibits hepatitis C virus replication both in vitro and in vivo, JOURNAL OF HEPATOLOGY, 55(1), 11-18, JUL 2011
  318. Effects of Hepatitis B Virus Infection on the Interferon Response in Immunodeficient Human Hepatocyte Chimeric Mice, JOURNAL OF INFECTIOUS DISEASES, 204(2), 224-228, JUL 15 2011
  319. IL28B But Not ITPA Polymorphism Is Predictive of Response to Pegylated Interferon, Ribavirin, and Telaprevir Triple Therapy in Patients With Genotype 1 Hepatitis C, JOURNAL OF INFECTIOUS DISEASES, 204(1), 84-93, JUL 1 2011
  320. Treatment Strategy for Early Hepatocellular Carcinomas: Comparison of Radiofrequency Ablation With or Without Transcatheter Arterial Chemoembolization and Surgical Resection, JOURNAL OF SURGICAL ONCOLOGY, 104(1), 3-9, JUL 1 2011
  321. Animal model for study of human hepatitis viruses, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 26(1), 13-18, JAN 2011
  322. Hepatitis C virus: How genetic variability affects pathobiology of disease, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 26, 83-95, JAN 2011
  323. Management of hepatitis B: Consensus of the Japan Society of Hepatology 2009, HEPATOLOGY RESEARCH, 41(1), 1-21, JAN 2011
  324. Measurement of Rho-associated kinase (ROCK) activity in humans: Validity of leukocyte p-MBS/t-MBS in comparison with vascular response to fasudil, ATHEROSCLEROSIS, 214(1), 117-121, JAN 2011
  325. Vascular Function and Circulating Progenitor Cells in Thromboangitis Obliterans (Buerger's Disease) and Atherosclerosis Obliterans, HYPERTENSION, 57(1), 70-U204, JAN 2011
  326. A simple clinical scoring system using ferritin, fasting insulin, and type IV collagen 7S for predicting steatohepatitis in nonalcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 46(2), 257-268, FEB 2011
  327. Advantages of endoscopic submucosal dissection versus endoscopic oblique aspiration mucosectomy for superficial esophageal tumors, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 26(2), 275-280, FEB 2011
  328. Autologous Bone-Marrow Mononuclear Cell Implantation Reduces Long-Term Major Amputation Risk in Patients With Critical Limb Ischemia A Comparison of Atherosclerotic Peripheral Arterial Disease and Buerger Disease, CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 4(1), 15-25, FEB 2011
  329. Calcium channel blocker and Rho-associated kinase activity in patients with hypertension, JOURNAL OF HYPERTENSION, 29(2), 373-379, FEB 2011
  330. Genetic pathways of multiple esophageal squamous cell carcinomas, ONCOLOGY REPORTS, 25(2), 453-459, FEB 2011
  331. HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy, GUT, 60(2), 261-267, FEB 2011
  332. Improved visibility of lesions of the small intestine via capsule endoscopy with computed virtual chromoendoscopy, GASTROINTESTINAL ENDOSCOPY, 73(2), 299-306, FEB 2011
  333. Influence of ITPA Polymorphisms on Decreases of Hemoglobin During Treatment with Pegylated Interferon, Ribavirin, and Telaprevir, HEPATOLOGY, 53(2), 415-421, FEB 2011
  334. Flow-mediated vasodilation is augmented in a corkscrew collateral artery compared with that in a native artery in patients with thromboangiitis obliterans (Buerger disease), JOURNAL OF VASCULAR SURGERY, 54(6), 1689-1697, DEC 2011
  335. Low Prevalence of Helicobacter pylori-negative Gastric Cancer among Japanese, HELICOBACTER, 16(6), 415-419, DEC 2011
  336. Quantitative analysis of colorectal lesions observed on magnified endoscopy images, JOURNAL OF GASTROENTEROLOGY, 46(12), 1382-1390, DEC 2011
  337. Hepatitis C Virus Infection Suppresses the Interferon Response in the Liver of the Human Hepatocyte Chimeric Mouse, PLOS ONE, 6(8), AUG 23 2011
  338. In Vivo Adaptation of Hepatitis C Virus in Chimpanzees for Efficient Virus Production and Evasion of Apoptosis, HEPATOLOGY, 54(2), 425-433, AUG 2011
  339. Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers, NATURE GENETICS, 43(8), 797-U108, AUG 2011
  340. A single nucleotide polymorphism in activated cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients, JOURNAL OF HEPATOLOGY, 54(4), 629-639, APR 2011
  341. Factors predictive of sustained virological response following 72 weeks of combination therapy for genotype 1b hepatitis C, JOURNAL OF GASTROENTEROLOGY, 46(4), 545-555, APR 2011
  342. Impact of Radiation and Hepatitis Virus Infection on Risk of Hepatocellular Carcinoma, HEPATOLOGY, 53(4), 1237-1245, APR 2011
  343. Intestinal tuberculosis with hoarseness as a chief complaint due to mediastinal lymphadenitis, Case Rep Gastroenterol, 5(3), 540-545, 20110901
  344. Prevention of hepatitis B virus reactivation in immunosuppressive therapy or chemotherapy., Clin Exp Nephrol., 20110601
  345. Portal-systemic shunt between the inferior mesenteric vein and inferior vena cava in a patient with hepatic encephalopathy: successful occlusion by balloon-occluded retrograde transvenous obliteration., Hiroshima J Med Sci, 60(1), 15-19, 20110501
  346. Will There Be an HCV Meeting in 2020? Summary of the 17th International Meeting on Hepatitis C Virus and Related Viruses., Gastroenterolog, 20110501
  347. Possibility of adoptive immunotherapy with peripheral blood-derived CD3⁻CD56+ and CD3+CD56+ cells for inducing antihepatocellular carcinoma and antihepatitis C virus activity., J Immunother, 34(2), 129-138, 20110301
  348. Current Status of Narrow-Band Imaging Magnifying Colonoscopy for Colorectal Neoplasia in Japan, DIGESTION, 83(3), 167-172, 2011
  349. Splenectomy in Chronic Hepatic Disorders: Portal Vein Thrombosis and Improvement of Liver Function, DIGESTIVE SURGERY, 28(1), 9-14, 2011
  350. Pilot Study of Systemic Combination Therapy with S-1, an Oral Fluoropyrimidine, and Cisplatin for Hepatocellular Carcinoma with Extrahepatic Metastases, HEPATO-GASTROENTEROLOGY, 57(102-03), 1272-1278, SEP-OCT 2010
  351. Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants, VIROLOGY, 405(2), 361-369, SEP 30 2010
  352. A multicenter, open-label, dose-ranging study to exploratively evaluate the efficacy, safety, and dose-response of tolvaptan in patients with decompensated liver cirrhosis, JOURNAL OF GASTROENTEROLOGY, 45(9), 979-987, SEP 2010
  353. Characterization of colorectal tumors using narrow-band imaging magnification: combined diagnosis with both pit pattern and microvessel features, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 45(9), 1084-1092, SEP 2010
  354. Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients, JOURNAL OF HEPATOLOGY, 53(3), 439-443, SEP 2010
  355. Evaluation of long-term entecavir treatment in stable chronic hepatitis B patients switched from lamivudine therapy, HEPATOLOGY INTERNATIONAL, 4(3), 594-600, SEP 2010
  356. Expression of platelet-derived growth factor (PDGF)-B and PDGF-receptor beta is associated with lymphatic metastasis in human gastric carcinoma, CANCER SCIENCE, 101(9), 1984-1989, SEP 2010
  357. Is Structural Remodeling of Fibrillated Atria the Consequence of Tissue Hypoxia?, CIRCULATION JOURNAL, 74(9), 1815-1821, SEP 2010
  358. ITPA Polymorphism Affects Ribavirin-Induced Anemia and Outcomes of Therapy-A Genome-Wide Study of Japanese HCV Virus Patients, GASTROENTEROLOGY, 139(4), 1190-1197, OCT 2010
  359. Potential role for vascular endothelial growth factor-D as an autocrine factor for human gastric carcinoma cells, CANCER SCIENCE, 101(10), 2121-2127, OCT 2010
  360. Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations, NATURE GENETICS, 42(10), 893-896, OCT 2010
  361. Clinical Impact of Tumor Invasion Depth Staging of Esophageal Squamous Cell Carcinoma Using Endoscopic Ultrasonography, HEPATO-GASTROENTEROLOGY, 58(104), 1423-1429, NOV-DEC 2010
  362. Evaluation of portosystemic collaterals by MDCT-MPR imaging for management of hemorrhagic esophageal varices, EUROPEAN JOURNAL OF RADIOLOGY, 76(2), 239-245, NOV 2010
  363. Outcome of endoscopic submucosal dissection for colorectal tumors accompanied by fibrosis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 45(11), 1329-1337, NOV 2010
  364. Quantitative analysis and development of a computer-aided system for identification of regular pit patterns of colorectal lesions, GASTROINTESTINAL ENDOSCOPY, 72(5), 1047-1051, NOV 2010
  365. Transcatheter chemoembolization for unresectable hepatocellular carcinoma and comparison of five staging systems, HEPATOLOGY RESEARCH, 40(11), 1082-1091, NOV 2010
  366. Mesenchymal stem cells enhance growth and metastasis of colon cancer, INTERNATIONAL JOURNAL OF CANCER, 127(10), 2323-2333, NOV 15 2010
  367. IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones, VIROLOGY, 407(1), 80-90, NOV 10 2010
  368. G to A hypermutation of TT virus, VIRUS RESEARCH, 149(2), 211-216, MAY 2010
  369. A spontaneous Type 1 electrocardiogram pattern in lead V-2 is an independent predictor of ventricular fibrillation in Brugada syndrome, EUROPACE, 12(3), 410-416, MAR 2010
  370. Percutaneous radiofrequency ablation as first-line treatment for small hepatocellular carcinoma: Results and prognostic factors on long-term follow up, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25(3), 597-604, MAR 2010
  371. Intra-arterial 5-fluorouracil/interferon combination therapy for hepatocellular carcinoma with portal vein tumor thrombosis and extrahepatic metastases, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25(6), 1117-1122, JUN 2010
  372. Long-term use of entecavir in nucleoside-naive Japanese patients with chronic hepatitis B infection, JOURNAL OF HEPATOLOGY, 52(6), 791-799, JUN 2010
  373. Pioglitazone improves endothelium-dependent vasodilation in hypertensive patients with impaired glucose tolerance in part through a decrease in oxidative stress, ATHEROSCLEROSIS, 210(2), 521-524, JUN 2010
  374. Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH, JOURNAL OF GASTROENTEROLOGY, 45(7), 750-757, JUL 2010
  375. Establishment of functional telomerase immortalized human hepatocytes and a hepatic stellate cell line for telomere-targeting anticancer drug development, CANCER SCIENCE, 101(7), 1678-1685, JUL 2010
  376. HBx protein is indispensable for development of viraemia in human hepatocyte chimeric mice, JOURNAL OF GENERAL VIROLOGY, 91, 1854-1864, JUL 2010
  377. Practical evaluation of a mouse with chimeric human liver model for hepatitis C virus infection using an NS3-4A protease inhibitor, JOURNAL OF GENERAL VIROLOGY, 91, 1668-1677, JUL 2010
  378. Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis B virus infection for the fiscal year 2008 in Japan, HEPATOLOGY RESEARCH, 40(1), 1-7, JAN 2010
  379. Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis C virus infection for the fiscal year 2008 in Japan, HEPATOLOGY RESEARCH, 40(1), 8-13, JAN 2010
  380. Regular surveillance by imaging for early detection and better prognosis of hepatocellular carcinoma in patients infected with hepatitis C virus, JOURNAL OF GASTROENTEROLOGY, 45(1), 105-112, JAN 2010
  381. Sarpogrelate Hydrochloride, a Selective 5-hydroxytryptamine(2A) Antagonist, Augments Autologous Bone Marrow Mononuclear Cell Implantation-induced Improvement in Endothelium-dependent Vasodilation in Patients With Critical Limb Ischemia, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 55(1), 56-61, JAN 2010
  382. Endothelial function in subjects with isolated low HDL cholesterol: role of nitric oxide and circulating progenitor cells, AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 298(2), E202-E209, FEB 2010
  383. Impaired myocardial blood flow reserve in subjects with metabolic syndrome analyzed using positron emission tomography and N-13 labeled ammonia, EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 37(2), 368-376, FEB 2010
  384. Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease, BMC MEDICAL GENETICS, 11, DEC 22 2010
  385. Accumulation of refractory factors for pegylated interferon plus ribavirin therapy in older female patients with chronic hepatitis C, HEPATOLOGY RESEARCH, 40(12), 1155-1167, DEC 2010
  386. Helicobacter pylori dupA and gastric acid secretion are negatively associated with gastric cancer development, JOURNAL OF MEDICAL MICROBIOLOGY, 59(12), 1484-1489, DEC 2010
  387. Predicting the absence of lymph node metastasis of submucosal invasive gastric cancer: Expansion of the criteria for curative endoscopic resection, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 45(12), 1480-1487, DEC 2010
  388. Prolongation of interferon therapy for recurrent hepatitis C after living donor liver transplantation: Analysis of predictive factors of sustained virological response, including amino acid sequence of the core and NS5A regions of hepatitis C virus, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 45(12), 1488-1496, DEC 2010
  389. Zoledronic acid delays disease progression of bone metastases from hepatocellular carcinoma, HEPATOLOGY RESEARCH, 40(12), 1195-1203, DEC 2010
  390. Amino Acid Substitution in Hepatitis C Virus Core Region and Genetic Variation Near the Interleukin 28B Gene Predict Viral Response to Telaprevir with Peginterferon and Ribavirin, HEPATOLOGY, 52(2), 421-429, AUG 2010
  391. Classification of Corkscrew Collaterals in Thromboangiitis Obliterans (Buerger's Disease) - Relationship Between Corkscrew Type and Prevalence of Ischemic Ulcers, CIRCULATION JOURNAL, 74(8), 1684-1688, AUG 2010
  392. Hypersensitivity Reactions to Transcatheter Chemoembolization with Cisplatin and Lipiodol Suspension for Unresectable Hepatocellular Carcinoma, JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 21(8), 1219-1225, AUG 2010
  393. Importance of Serum Concentration of Adefovir for Lamivudine-Adefovir Combination Therapy in Patients with Lamivudine-Resistant Chronic Hepatitis B, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 54(8), 3205-3211, AUG 2010
  394. Elimination of Hepatitis C Virus by Short Term NS3-4A and NS5B Inhibitor Combination Therapy in Human Hepatocyte Chimeric Mice., J Hepatol., 20101001
  395. Efficacy of ecabet sodium enema on intractable rectal ulcer after piecemeal endoscopic mucosal resection for rectal tumor, Clin J Gastroenterol, 3(6), 285-288, 20100901
  396. Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations, Nat Genet, 42(10), 893-6, 20100901
  397. Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin., Hepatology, 52(2), 421-429, 20100801
  398. Impaired coronary microvascular endothelial function in men with metabolic syndrome., World J Cardiol, 26(7), 205-210, 20100701
  399. Non-polypoid colorectal neoplasms in ulcerative colitis, Gastrointest Endosc, 20(3), 525-542, 20100701
  400. Characteristics of esophageal squamous cell carcinomas and lugol-voiding lesions in patients with head and neck squamous cell carcinoma, J Clin Gastroenterol, 44(2), e27-33, 20100201
  401. A Water-soluble extract from culture medium of ganoderma lucidum mycelia suppresses the development of colorectal adenoma, Hiroshima J Med Sci, 59(1), 1--6, 20100101
  402. Amino acid substitutions in core and NS5A regions of the HCV genome can predict virological decrease with pegylated interferon plus ribavirin therapy, ANTIVIRAL THERAPY, 15(8), 1087-1097, 2010
  403. Differential effects of interferon and lamivudine on serum HBV RNA inhibition in patients with chronic hepatitis B, ANTIVIRAL THERAPY, 15(2), 177-184, 2010
  404. Natural Course of Lugol-Voiding Lesions in Patients with Superficial Esophageal Squamous Cell Carcinoma, DIGESTION, 82(1), 60-65, 2010
  405. Relationship between Helicobacter pylori Tyrosine-Phosphorylated CagA-Related Markers and the Development of Diffuse-Type Gastric Cancers: A Case-Control Study, DIGESTION, 82(1), 10-17, 2010
  406. Synchronous and Subsequent Lesions of Serrated Adenomas and Tubular Adenomas of the Colorectum, PATHOBIOLOGY, 77(5), 273-277, 2010
  407. Antiviral activity, dose-response relationship, and safety of entecavir following 24-week oral dosing in nucleoside-naive Japanese adult patients with chronic hepatitis B: a randomized, double-blind, phase II clinical trial, HEPATOLOGY INTERNATIONAL, 3(3), 445-452, SEP 2009
  408. Predictive values of amino acid sequences of the core and NS5A regions in antiviral therapy for hepatitis C: a Japanese multi-center study, JOURNAL OF GASTROENTEROLOGY, 44(9), 952-963, SEP 2009
  409. Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease, ATHEROSCLEROSIS, 206(2), 604-610, OCT 2009
  410. Adoptive immunotherapy with liver allograft-derived lymphocytes induces anti-HCV activity after liver transplantation in humans and humanized mice, JOURNAL OF CLINICAL INVESTIGATION, 119(11), 3226-3235, NOV 2009
  411. Ecabet sodium induces neuronal nitric oxide synthase-derived nitric oxide synthesis and gastric adaptive relaxation in the human stomach, JOURNAL OF GASTROENTEROLOGY, 44(11), 1118-1124, NOV 2009
  412. Little Necessity of Acid Inhibition against Proton Pump Inhibitor Rebound Effects and Prior Helicobacter pylori Eradication Therapy in Gastric Ulcer Patients: A Randomized Prospective Study, HEPATO-GASTROENTEROLOGY, 56(91-92), 624-628, MAY-JUN 2009
  413. A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians, NATURE GENETICS, 41(5), 591-595, MAY 2009
  414. A Polymorphism in MAPKAPK3 Affects Response to Interferon Therapy for Chronic Hepatitis C, GASTROENTEROLOGY, 136(5), 1796-1805, MAY 2009
  415. Clinical prevention of gastric cancer by Helicobacter pylori eradication therapy: a systematic review, JOURNAL OF GASTROENTEROLOGY, 44(5), 365-371, MAY 2009
  416. Evaluation and validation of computed virtual chromoendoscopy in early gastric cancer, GASTROINTESTINAL ENDOSCOPY, 69(6), 1052-1058, MAY 2009
  417. Intra-arterial 5-fluorouracil/interferon combination therapy for advanced hepatocellular carcinoma with or without three-dimensional conformal radiotherapy for portal vein tumor thrombosis, JOURNAL OF GASTROENTEROLOGY, 44(5), 492-502, MAY 2009
  418. Pathogenetic role of the tyrosine-phosphorylated CagA EPIYA sequence of Helicobacter pylori in histological gastritis in Japanese patients, JOURNAL OF GASTROENTEROLOGY, 44(5), 405-411, MAY 2009
  419. Dose comparison study of pegylated interferon-alpha-2b plus ribavirin in naive Japanese patients with hepatitis C virus genotype 2: A randomized clinical trial, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24(3), 366-371, MAR 2009
  420. Narrow-band imaging magnification predicts the histology and invasion depth of colorectal tumors, GASTROINTESTINAL ENDOSCOPY, 69(3), 631-636, MAR 2009
  421. The first Japanese case of COACH syndrome, HEPATOLOGY RESEARCH, 39(3), 318-323, MAR 2009
  422. Antibodies to Helicobacter pylori and CagA protein are associated with the response to antibacterial therapy in patients with H-pylori-positive API2-MALT1-negative gastric MALT lymphoma, CANCER SCIENCE, 100(6), 1075-1081, JUN 2009
  423. Deletion of angiotensin II type I receptor reduces hepatic steatosis, JOURNAL OF HEPATOLOGY, 50(6), 1226-1235, JUN 2009
  424. Nifedipine Interferes with Migration of Vascular Smooth Muscle Cells via Inhibition of Pyk2-Src Axis, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 16(3), 230-238, JUN 2009
  425. Predicting the response to 48-week combination therapy with peginterferon alpha-2b plus ribavirin from the estimated HCV RNA load index after negative serum change in genotype 1b hepatitis C patients, HEPATOLOGY RESEARCH, 39(6), 531-538, JUN 2009
  426. G-to-A Hypermutation in Hepatitis B Virus (HBV) and Clinical Course of Patients with Chronic HBV Infection, JOURNAL OF INFECTIOUS DISEASES, 199(11), 1599-1607, JUN 1 2009
  427. Chronic hepatitis C in patients co-infected with human immunodeficiency virus in Japan: a retrospective multicenter analysis, HEPATOLOGY RESEARCH, 39(7), 657-663, JUL 2009
  428. KNACK AND PRACTICAL TECHNIQUE OF COLONOSCOPIC TREATMENT FOCUSED ON ENDOSCOPIC MUCOSAL RESECTION USING SNARE, DIGESTIVE ENDOSCOPY, 21, S38-S42, JUL 2009
  429. Predicting the clinical response to cytapheresis in steroid-refractory or -dependent ulcerative colitis using contrast-enhanced ultrasonography, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 44(7), 831-837, JUL 2009
  430. THERAPEUTIC STRATEGY FOR COLORECTAL LATERALLY SPREADING TUMOR, DIGESTIVE ENDOSCOPY, 21, S43-S46, JUL 2009
  431. Transarterial Infusion Chemotherapy Using Cisplatin-Lipiodol Suspension With or Without Embolization for Unresectable Hepatocellular Carcinoma, CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 32(4), 687-694, JUL 2009
  432. Evaluation of Patients with Esophageal Varices After Endoscopic Injection Sclerotherapy Using Multiplanar Reconstruction MDCT Images, AMERICAN JOURNAL OF ROENTGENOLOGY, 192(1), 122-130, JAN 2009
  433. Involvement of Epithelial Cell Transforming Sequence-2 Oncoantigen in Lung and Esophageal Cancer Progression, CLINICAL CANCER RESEARCH, 15(1), 256-266, JAN 1 2009
  434. FDG positron emission tomography/computed tomography for the detection of extrahepatic metastases from hepatocellular carcinoma, HEPATOLOGY RESEARCH, 39(2), 134-142, FEB 2009
  435. Significant Correlation Between Spleen Volume and Thrombocytopenia in Liver Transplant Patients: A Concept for Predicting Persistent Thrombocytopenia, LIVER TRANSPLANTATION, 15(2), 208-215, FEB 2009
  436. Absence of viral interference and different susceptibility to interferon between hepatitis B virus and hepatitis C virus in human hepatocyte chimeric mice, JOURNAL OF HEPATOLOGY, 51(6), 1046-1054, DEC 2009
  437. Detection of Helicobacter hepaticus in Human Bile Samples of Patients with Biliary Disease, HELICOBACTER, 14(6), 545-551, DEC 2009
  438. Effects of structural variations of APOBEC3A and APOBEC3B genes in chronic hepatitis B virus infection, HEPATOLOGY RESEARCH, 39(12), 1159-1168, DEC 2009
  439. Amphipathic DNA Polymers Inhibit Hepatitis C Virus Infection by Blocking Viral Entry, GASTROENTEROLOGY, 137(2), 673-681, AUG 2009
  440. Meta-analysis used to identify factors associated with the effectiveness of proton pump inhibitors against non-erosive reflux disease, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24(8), 1326-1332, AUG 2009
  441. Successful hepatitis B vaccination in liver transplant recipients with donor-specific hyporesponsiveness, TRANSPLANT INTERNATIONAL, 22(8), 805-813, AUG 2009
  442. Cigarette Smoking Abolishes Ischemic Preconditioning-Induced Augmentation of Endothelium-Dependent Vasodilation, HYPERTENSION, 53(4), 674-U151, APR 2009
  443. Comparison of detectability of small-bowel lesions between capsule endoscopy and double-balloon endoscopy for patients with suspected small-bowel disease, GASTROINTESTINAL ENDOSCOPY, 69(4), 857-865, APR 2009
  444. Effectiveness of prokinetic agents against diseases external to the gastrointestinal tract, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24(4), 537-546, APR 2009
  445. Metachronous multiple esophageal squamous cell carcinomas and Lugol-voiding lesions after endoscopic mucosal resection, ENDOSCOPY, 41(4), 304-309, APR 2009
  446. Randomized Trial of High-Dose Interferon-alpha-2b Combined With Ribavirin in Patients With Chronic Hepatitis C: Correlation Between Amino Acid Substitutions in the Core/NS5A Region and Virological Response to Interferon Therapy, JOURNAL OF MEDICAL VIROLOGY, 81(4), 640-649, APR 2009
  447. Successful treatment of pulmonary metastases associated with advanced hepatocellular carcinoma by systemic 5-fluorouracil combined with interferon-alpha in a hemodialysis patient, HEPATOLOGY RESEARCH, 39(4), 415-420, APR 2009
  448. Usefulness of Endoscopic Ultrasonography in Determining the Depth of Invasion and Indication for Endoscopic Treatment of Early Gastric Cancer, JOURNAL OF CLINICAL GASTROENTEROLOGY, 43(4), 318-322, APR 2009
  449. Infliximab treatment for Crohn's disease in a patient with IgA nephropathy, Clin J Gastroenterol, 2, 380-383, 20091201
  450. Cheilitis granulomatosa as an early manifestation of Crohn's disease, Clin J Gastroenterol, 2, 190-193, 20091001
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  452. Trend in Japanese malpractice litigation involving gastrointestinal endoscopy, Am J Gastroenterol, 104(1), 251-252, 20090101
  453. Usefulness and limitations of transabdominal ultrasonography for detecting small-bowel tumors, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 44(3), 332-338, 2009
  454. Optical biopsy of early gastroesophageal cancer by catheter-based reflectance-type laser-scanning confocal microscopy, JOURNAL OF BIOMEDICAL OPTICS, 13(5), SEP-OCT 2008
  455. Prophylaxis against Recurrence of HBV Hepatitis after Living-donor Liver Transplantation, HEPATO-GASTROENTEROLOGY, 55(86-87), 1746-1749, SEP-OCT 2008
  456. Colorectal endoscopic submucosal dissection: present status and future perspective, including its differentiation from endoscopic mucosal resection, JOURNAL OF GASTROENTEROLOGY, 43(9), 641-651, SEP 2008
  457. Establishment of an infectious genotype 1b hepatitis C virus clone in human hepatocyte chimeric mice, JOURNAL OF GENERAL VIROLOGY, 89, 2108-2113, SEP 2008
  458. Presence of Poorly Differentiated Component Correlated with Submucosal Invasion in the Early Diffuse-type Gastric Cancer, HEPATO-GASTROENTEROLOGY, 55(88), 2264-2268, NOV-DEC 2008
  459. Aging and Hypertension Are Independent Risk Factors for Reduced Number of Circulating Endothelial Progenitor Cells, AMERICAN JOURNAL OF HYPERTENSION, 21(11), 1203-1209, NOV 2008
  460. Vascular Endothelial Growth Factor C Stimulates Progression of Human Gastric Cancer via Both Autocrine and Paracrine Mechanisms, CLINICAL CANCER RESEARCH, 14(22), 7205-7214, NOV 15 2008
  461. Strategy for treatment of nonerosive reflux disease in Asia, WORLD JOURNAL OF GASTROENTEROLOGY, 14(20), 3123-3128, MAY 28 2008
  462. Angiotensin II-Induced osteopontin expression in vascular smooth muscle cells involves G(q/11), Ras, ERK, Src and Ets-1, HYPERTENSION RESEARCH, 31(5), 987-998, MAY 2008
  463. Genetic polymorphisms and head and neck cancer risk (Review), INTERNATIONAL JOURNAL OF ONCOLOGY, 32(5), 945-973, MAY 2008
  464. Long-term ultrasonographic follow-up study of gastric motility in patients with functional dyspepsia, JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 42(2), 144-149, MAR 2008
  465. Role of the angiotensin II type 2 receptor in arterial remodeling after wire injury in mice, HYPERTENSION RESEARCH, 31(6), 1241-1249, JUN 2008
  466. Clinicopathological features of elderly patients with hepatitis C virus-related hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY, 43(7), 550-557, JUL 2008
  467. Coronary vasospasm produces reversible perfusion defects observed during adenosine triphosphate stress myocardial single-photon emission computed tomography, CLINICAL CARDIOLOGY, 31(7), 310-316, JUL 2008
  468. Cytoprotective effect of tauroursodeoxycholate on hepatocyte apoptosis induced by peroxisome proliferator-activated receptor gamma ligand, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23(7), E198-E206, JUL 2008
  469. Evaluation of gastric cancer risk using topography of histological gastritis: A large-scaled cross-sectional study, DIGESTIVE DISEASES AND SCIENCES, 53(7), 1818-1823, JUL 2008
  470. Relationship between Augmentation Index and Flow-Mediated Vasodilation in the Brachial Artery, HYPERTENSION RESEARCH, 31(7), 1293-1298, JUL 2008
  471. Clinical significance of type V-I pit pattern subclassification in determining the depth of invasion of colorectal neoplasms, WORLD JOURNAL OF GASTROENTEROLOGY, 14(2), 211-217, JAN 14 2008
  472. Susceptibility of chimeric mice with livers repopulated by serially subcultured human hepatocytes to hepatitis B virus, HEPATOLOGY, 47(2), 435-446, FEB 2008
  473. Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients, HYPERTENSION, 51(2), 446-453, FEB 1 2008
  474. Beneficial effects of living-donor liver transplantation on esophageal varices, JOURNAL OF GASTROENTEROLOGY, 43(12), 982-989, DEC 2008
  475. Efficacy of atorvastatin for the treatment of nonalcoholic steatohepatitis with dyslipidemia, METABOLISM-CLINICAL AND EXPERIMENTAL, 57(12), 1711-1718, DEC 2008
  476. Expression of multidrug resistance-associated protein 2 is involved in chemotherapy resistance in human pancreatic cancer, INTERNATIONAL JOURNAL OF ONCOLOGY, 33(6), 1187-1194, DEC 2008
  477. Etiology and outcome of acute liver failure: Retrospective analysis of 50 patients treated at a single center, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23(8), 1216-1222, AUG 2008
  478. Systemic gemcitabine combined with intra-arterial low-dose cisplatin and 5-fluorouracil for advanced hepatocellular carcinoma: Seven cases, WORLD JOURNAL OF GASTROENTEROLOGY, 14(16), 2602-2608, APR 28 2008
  479. Ablation of the Bach1 gene leads to the suppression of atherosclerosis in Bach1 and apolipoprotein E double knockout mice, HYPERTENSION RESEARCH, 31(4), 783-792, APR 2008
  480. Prospective study of short-term peginterferon-alpha-2a monotherapy in patients who had a virological response at 2 weeks after initiation of interferon therapy, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23(4), 541-545, APR 2008
  481. Risk factors for hepatocellular carcinoma in a Japanese population: A nested case-control study, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 17(4), 846-854, APR 2008
  482. Rapid progression of Epstein -Barr-virus-positive gastric diffuse large B-cell lymphoma during chemoradiotherapy: a case report, Clin J Gastroenterol, 1, 105-109, 20081218
  483. Strategy of endoscopic treatment for colorectal tumor: recent progress and perspective, 353-366, 20080815
  484. Endoscopic ultrasonography with double baloon enteroscopy for small bowel diseases, Techniques in Gastrointestinal Endoscopy, 10(3), 113-118, 20080724
  485. A Case of Fulminant Hepatic Failure Caused by Hepatitis E virus79117, Clinical Journal of gastroenterology, 1, 69-74, 20080603
  486. The number of criminal prosecutions against physicians due to medical negligence is on the rise in Japan, Am J Emerg Med, 26(1), 105-106, 20080117
  487. Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells, JOURNAL OF GASTROENTEROLOGY, 43(4), 298-304, 2008
  488. Combination therapy of oral fluoropyrimidine anticancer drug S-1 and interferon alpha for HCC patients with extrahepatic metastases, ONCOLOGY, 75(1-2), 8-16, 2008
  489. Evaluation of colon cancer vascularity by flash echo imaging, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 43(2), 223-228, 2008
  490. Predictors and long-term prognostic implications of angiographic slow/no-flow during percutaneous coronary intervention for acute myocardial infarction, INTERNAL MEDICINE, 47(10), 899-906, 2008
  491. Relation between histologic gastritis and gastric motility in Japanese patients with functional dyspepsia: evaluation by transabdominal ultrasonography, JOURNAL OF GASTROENTEROLOGY, 43(5), 332-337, 2008
  492. Role of the Gastrin-Gastrin Receptor System in the Expansive Growth of Human Gastric Neoplasms, DIGESTION, 78(2-3), 163-170, 2008
  493. Validating a Markov Model of Treatment for Hepatitis C Virus-related Hepatocellular Carcinoma, METHODS OF INFORMATION IN MEDICINE, 47(6), 529-540, 2008
  494. Pycnogenol (R), French maritime pine bark extract, augments endothelium-dependent vasodilation in humans, HYPERTENSION RESEARCH, 30(9), 775-780, SEP 2007
  495. Serum pepsinogen levels in the Japanese population: Prospective study of 9 years of follow-up, HEPATO-GASTROENTEROLOGY, 54(78), 1887-1890, SEP 2007
  496. Effects of a 24-week course of interferon-a therapy after curative treatment of hepatitis C virus-associated hepatocellular carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(40), 5343-5350, OCT 28 2007
  497. Low-dose intermittent interferon-alpha therapy for HCV-related liver cirrhosis after curative treatment of hepatocellular carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(39), 5188-5195, OCT 21 2007
  498. Nodular gastritis with Helicobacter pylori infection is strongly associated with diffuse-type gastric cancer in young patients, DIGESTIVE ENDOSCOPY, 19(4), 180-184, OCT 2007
  499. Pretreatment predictor of response, time to progression, and survival to intraarterial 5-fluorouracil/interferon combination therapy in patients with advanced hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY, 42(10), 845-853, OCT 2007
  500. Treatment of functional dyspepsia with serotonin agonists: A meta-analysis of randomized controlled trials, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(10), 1566-1570, OCT 2007
  501. Genetic polymorphisms and esophageal cancer risk, INTERNATIONAL JOURNAL OF CANCER, 121(8), 1643-1658, OCT 15 2007
  502. Biliary complications after duct-to-duct biliary reconstruction in living-donor liver transplantation: Causes and treatment, WORLD JOURNAL OF SURGERY, 31(11), 2222-2229, NOV 2007
  503. Evaluation of microvessels in colorectal tumors by narrow band imaging magnification, GASTROINTESTINAL ENDOSCOPY, 66(5), 945-952, NOV 2007
  504. Similar effects of recombinant interferon-alpha-2b and natural interferon-alpha when combined with intra-arterial 5-fluorouracil for the treatment of advanced hepatocellular carcinoma, LIVER INTERNATIONAL, 27(9), 1209-1216, NOV 2007
  505. Measurement of flow-mediated vasodilation of the brachial artery - A comparison of measurements in the seated and supine positions, CIRCULATION JOURNAL, 71(5), 736-740, MAY 2007
  506. Role of Helicobacter pylori infection and chronic inflammation in gastric cancer in the cardia, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 37(5), 365-369, MAY 2007
  507. Serum HBV RNA is a predictor of early emergence of the YMDD mutant in patients treated with lamivudine, HEPATOLOGY, 45(5), 1179-1186, MAY 2007
  508. Earthworm fibrinolytic enzyme: anti-tumor activity on human hepatoma cells in vitro and in vivo, CHINESE MEDICAL JOURNAL, 120(10), 898-904, MAY 20 2007
  509. Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon, FEBS LETTERS, 581(10), 1983-1987, MAY 15 2007
  510. Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(3), 304-310, MAR 2007
  511. Usefulness of EUS with double-balloon enteroscopy for diagnosis of small-bowel diseases, GASTROINTESTINAL ENDOSCOPY, 65(3), 412-420, MAR 2007
  512. Clinical significance of mucosal suppressors of cytokine signaling 3 expression in ulcerative colitis, WORLD JOURNAL OF GASTROENTEROLOGY, 13(21), 2939-2944, JUN 7 2007
  513. Magnifying endoscopy with narrow band imaging for diagnosis of colorectal tumors, GASTROINTESTINAL ENDOSCOPY, 65(7), 988-995, JUN 2007
  514. Repetition of ischemic preconditioning augments endothelium-dependent vasodilation in humans - Role of endothelium-derived nitric oxide and endothelial progenitor cells, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 27(6), 1403-1410, JUN 2007
  515. Immunohistochemical molecular markers as predictors of curability of endoscopically resected submucosal colorectal cancer, WORLD JOURNAL OF GASTROENTEROLOGY, 13(28), 3829-3835, JUL 28 2007
  516. Elevated levels of serum advanced glycation end products in patients with non-alcoholic steatohepatitis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(7), 1112-1119, JUL 2007
  517. Endoscopic submucosal dissection for colorectal neoplasia: possibility of standardization, GASTROINTESTINAL ENDOSCOPY, 66(1), 100-107, JUL 2007
  518. Optical biopsy of GI lesions by reflectance-type laser-scanning confocal microscopy, GASTROINTESTINAL ENDOSCOPY, 66(1), 144-149, JUL 2007
  519. Techniques and pitfalls of endoscopic submucosal dissection for colorectal tumors, DIGESTIVE ENDOSCOPY, 19, S30-S33, JUL 2007
  520. Clinical features and prognosis of patients with extrahepatic metastases from hepatocellular carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(3), 414-420, JAN 21 2007
  521. Basis of decreased risk of gastric cancer in severe atrophic gastritis with eradication of Helicobacter pylori, DIGESTIVE DISEASES AND SCIENCES, 52(1), 232-239, JAN 2007
  522. Gene delivery of paraoxonase-1 inhibits neointimal hyperplasia after arterial balloon-injury in rabbits fed a high-fat diet, HYPERTENSION RESEARCH, 30(1), 85-91, JAN 2007
  523. Lymphatic vessel density at the site of deepest penetration as a predictor of lymph node metastasis in submucosal colorectal cancer, DISEASES OF THE COLON & RECTUM, 50(1), 13-21, JAN 2007
  524. Non-SCN5A related Brugada syndromes: Verification of normal splicing and trafficking of SCN5A without exonic mutations, ANNALS OF HUMAN GENETICS, 71, 8-17, JAN 2007
  525. Cavernous hemangioma in the ascending colon treated by endoscopic mucosal resection, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(2), 280-281, FEB 2007
  526. Dual effect of APOBEC3G on Hepatitis B virus, JOURNAL OF GENERAL VIROLOGY, 88, 432-440, FEB 2007
  527. Immune response to CagA protein is associated with improved platelet count after Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura, HELICOBACTER, 12(1), 36-42, FEB 2007
  528. Roles of Rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 49(6), 698-705, FEB 13 2007
  529. Selective decrease in colonic CD56(+) T and CD161(+) T cells in the inflamed mucosa of patients with ulcerative colitis, WORLD JOURNAL OF GASTROENTEROLOGY, 13(45), 5995-6002, DEC 7 2007
  530. Single lymphocyte analysis with a microwell array chip, CYTOMETRY PART A, 71A(12), 1003-1010, DEC 2007
  531. Successful treatment of an entecavir-resistant hepatitis B virus variant, JOURNAL OF MEDICAL VIROLOGY, 79(12), 1811-1817, DEC 2007
  532. Involvement of Kruppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(29), 3932-3938, AUG 7 2007
  533. Acute moderate-intensity exercise induces vasodilation through oxide bioavailiability an increase in nitric in humans, AMERICAN JOURNAL OF HYPERTENSION, 20(8), 825-830, AUG 2007
  534. Low serum level of hepatitis B indicates unlikely reactivation core-related antigen of hepatitis after cessation of lamivudine therapy, HEPATOLOGY RESEARCH, 37(8), 661-666, AUG 2007
  535. The long-term outcome of patients with bleeding gastric varices after balloon-occluded retrograde transvenous obliteration, JOURNAL OF GASTROENTEROLOGY, 42(8), 663-672, AUG 2007
  536. Host factors contributing to the discovery of gastric cancer after successful eradication therapy of Helicobacter pylori: Preliminary report, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(4), 571-576, APR 2007
  537. New method of evaluating gastric mucosal blood flow by ultrasound, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 42(4), 513-518, APR 2007
  538. Reduced expression of heme oxygenase-1 in patients with coronary atherosclerosis, HYPERTENSION RESEARCH, 30(4), 341-348, APR 2007
  539. Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 49(4), 221-227, APR 2007
  540. Primary follicular lymphoma of the gastrointestinal tract: a retrospective case series, Endoscopy, 20071201
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  542. Pycnogenol, French maritime pine bark extract, augments endothelium-dependent vasodilation in humans., HYPERTENSION RESEARCH, 775-780, 20070901
  543. Predicting the need for surgery in Crohn's disease with contrast harmonic ultrasound, Scand J Gastroenterol, 42, 577-585, 20070601
  544. Should splenectomy be performed for hepatitis C patients undergoing living-donor liver transplantation, J Gastroenterol Hepatol, 22(6), 959-960, 20070601
  545. Helicobacter pylori-associated gastritisis related to babA2expression without heterogeneity of the 3' region of the cagA genotype in Gastric Biopsy Specimens, Pathobiology, 74(5), 1-7, 20070401
  546. The effects of different intensities of acute exercise on systemic hemodynamics and forearm vascular function in humans., AMERICAN JUORNAL OF HYPERTENSION, 825-830, 20070214
  547. Carvedilol improves endothelium-dependent vasodilation in patients with dilated cardiomyopathy., HEART, 247-248, 20070201
  548. Balloon-occluded retrograde transvenous obliteration for portal-systemic encephalopathy due to superior mesenteric-caval shunt via the right gonadal vein, INTERNAL MEDICINE, 46(17), 1479-1480, 2007
  549. Efficacy of percutaneous cementoplasty for bone metastasis from hepatocellular carcinoma, ONCOLOGY, 72(5-6), 285-292, 2007
  550. Eicosapentaenoic acid could permit maintenance of the original ribavirin dose in chronic hepatitis C virus patients during the first 12 weeks of combination therapy with pegylated interferon-alpha and ribavirin, INTERVIROLOGY, 50(6), 439-446, 2007
  551. Helicobacter pylori - Associated gastritis is related to babA2 expression without heterogeneity of the 3 ' region of the cagA genotype in gastric biopsy specimens, PATHOBIOLOGY, 74(5), 309-316, 2007
  552. Predicting the need for surgery in Crohn's disease with contrast harmonic ultrasound, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 42(5), 577-585, 2007
  553. A case of Crohn's disease with hydronephrosis caused by ureteropelvic junction obstruction, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 18(9), 1015-1018, SEP 2006
  554. A ligand for peroxisome proliferator-activated receptor gamma inhibits human cholangiocarcinoma cell growth: Potential molecular targeting strategy for cholangioma, DIGESTIVE DISEASES AND SCIENCES, 51(9), 1650-1657, SEP 2006
  555. Helicobacter pylori infection is the major risk factor for gastric inflammation in the cardia, DIGESTIVE DISEASES AND SCIENCES, 51(9), 1582-1588, SEP 2006
  556. Medical malpractice litigation in gastroenterological practice in Japan: A 22-yr review of civil court cases, AMERICAN JOURNAL OF GASTROENTEROLOGY, 101(9), 1951-1953, SEP 2006
  557. Autologous bone marrow mononuclear cell implantation induces angiogenesis and bone regeneration in a patient with compartment syndrome, CIRCULATION JOURNAL, 70(10), 1362-1364, OCT 2006
  558. Endoscopic submucosal dissection for residual/local recurrence of early gastric cancer after endoscopic mucosal resection, ENDOSCOPY, 38(10), 996-1000, OCT 2006
  559. Genetic progression and divergence in superficial esophageal squamous cell carcinoma by loss of heterozygosity analysis, ONCOLOGY REPORTS, 16(4), 685-691, OCT 2006
  560. High-magnification colonoscopy (with videos), GASTROINTESTINAL ENDOSCOPY, 64(4), 604-613, OCT 2006
  561. Management of intraductal papillary-mucinous neoplasm of the pancreas - Treatment strategy based on morphologic classification, JOURNAL OF CLINICAL GASTROENTEROLOGY, 40(9), 856-862, OCT 2006
  562. Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 50(11), 3867-3874, NOV 2006
  563. Medical malpractice litigation related to gastrointestinal endoscopy in Japan: A two-decade review of civil court cases, WORLD JOURNAL OF GASTROENTEROLOGY, 12(42), 6857-6860, NOV 14 2006
  564. Surface structure of antral gastric mucosa represents the status of histologic gastritis: Fundamental evidence for the evaluation of antral gastritis by magnifying endoscopy, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 21(5), 837-841, MAY 2006
  565. Aged garlic extract has potential suppressive effect on colorectal adenomas in humans, JOURNAL OF NUTRITION, 136(3), 821S-826S, MAR 2006
  566. Deletion of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach, INTERNATIONAL JOURNAL OF ONCOLOGY, 28(6), 1361-1367, JUN 2006
  567. Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production, ATHEROSCLEROSIS, 186(2), 390-395, JUN 2006
  568. Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 346(1), 67-73, JUL 21 2006
  569. A case of multiple hepatic peribiliary cysts which contributed to the obstructive jaundice and led to liver failure at the young man with von Recklinghausen's disease, HEPATOLOGY RESEARCH, 35(3), 222-227, JUL 2006
  570. Clinicopathologic and genetic characteristics of gastric cancer in young male and female patients, ONCOLOGY REPORTS, 16(1), 11-15, JUL 2006
  571. Double-balloon enteroscopy in patients with GI bleeding of obscure origin, GASTROINTESTINAL ENDOSCOPY, 64(1), 135-140, JUL 2006
  572. Gastrointestinal stromal tumor in jejunum: Diagnosis using contrast-enhanced ultrasonography and double-balloon enteroscopy, DIGESTIVE DISEASES AND SCIENCES, 51(7), 1236-1240, JUL 2006
  573. Neuropilin-1 is involved in regulation of apoptosis and migration of human colon cancer, INTERNATIONAL JOURNAL OF ONCOLOGY, 29(1), 105-116, JUL 2006
  574. Real-time visualization and quantitation of canine gastric mucosal blood flow by contrast-enhanced ultrasonography, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 41(7), 856-861, JUL 2006
  575. dEvaluation of endoscopic and histological findings in Helicobacter pylori-positive Japanese young adults, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 21(1), 258-261, JAN 2006
  576. Measurement of hepatitis B virus core-related antigen is valuable for identifying patients who are at low risk of lamivudine resistance, LIVER INTERNATIONAL, 26(1), 90-96, FEB 2006
  577. Nonpolypoid (flat and depressed) colorectal neoplasms, GASTROENTEROLOGY, 130(2), 566-576, FEB 2006
  578. Suppression of STAT3 activity by duplin, which is a negative regulator of the Wnt signal, JOURNAL OF BIOCHEMISTRY, 139(2), 305-314, FEB 2006
  579. Defensive medicine practices among gastroenterologists in Japan, WORLD JOURNAL OF GASTROENTEROLOGY, 12(47), 7671-7675, DEC 21 2006
  580. Advantage of endoscopic submucosal dissection compared with EMR for early gastric cancer, GASTROINTESTINAL ENDOSCOPY, 64(6), 877-883, DEC 2006
  581. Feasibility of freeze-dried sera for serological and molecular biological detection of hepatitis B and C viruses, JOURNAL OF CLINICAL MICROBIOLOGY, 44(12), 4593-4595, DEC 2006
  582. Genetic and pathologic characteristics of gastrointestinal stromal tumors in extragastric lesions, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 18(6), 1067-1071, DEC 2006
  583. Small-intestinal Peutz-Jeghers polyps resected by endoscopic polypectomy with double-balloon enteroscopy and removal confirmed by ultrasonography, DIGESTIVE DISEASES AND SCIENCES, 51(12), 2337-2340, DEC 2006
  584. Effects of acute administration of caffeine on vascular function, AMERICAN JOURNAL OF CARDIOLOGY, 98(11), 1538-1541, DEC 1 2006
  585. Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 346(3), 658-664, AUG 4 2006
  586. Oxidative stress, endothelial function and angiogenesis induced by cell therapy and gene therapy, CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 7(2), 109-116, APR 2006
  587. The effect of Helicobacter pylori eradication therapy on gastric ulcer healing after endoscopic mucosal resection, JOURNAL OF CLINICAL GASTROENTEROLOGY, 40(4), 293-296, APR 2006
  588. The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines, INTERNATIONAL JOURNAL OF ONCOLOGY, 28(4), 915-921, APR 2006
  589. The usefulness of transabdominal ultrasound for the diagnosis of lower gastrointestinal bleeding, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 23(8), 1267-1272, APR 15 2006
  590. High-magnification colonoscopy (with Videos), Gastrointest Endosc, 64(4), 604-613, 20061001
  591. Management of Intraductal Papillary -mucinous Neoplasm of the Pancreas, J Clin Gastroenterol, 40(9), 856-862, 20061001
  592. Suppression of interferon-related promoter activation by hepatitis C virus proteins expressed in cultured cells., Hiroshima Journal of Medical Sciences, 55(3), 71-77, 20060901
  593. Pit pattern diagnosis for colorectal neoplasia using narrow band imaging magnification, Dig Endosc, 18, S52-S56, 20060701
  594. Delection of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach., Int J Oncology, 28, 1361-1367, 20060601
  595. Ablation of indiopathic ventricular tachycardia with a left Bundle-Branch block morphology originating from the pulmonary artery., J Arrthmia, 22(3), 180-186, 20060401
  596. Coronary sinus Morphology in Patients with Posteroseptal Atrioventricular Accessory Pathways., J Arrthmia, 22(3), 149-154, 20060401
  597. Edaravone(3-Methyl-1-Phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases., Recent Patents on Cardiovascular Drug Discovery, 1, 85-93, 20060401
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  601. Development of a novel method to detect Helicobacter pylori cagA genotype from paraffin-embedded materials: Comparison between patients with duodenal ulcer and gastric cancer in young Japanese, DIGESTION, 73(1), 47-53, 2006
  602. Evolution of hepatitis C virus quasispecies during ribavirin and interferon-alpha-2b combination therapy and interferon-alpha-2b monotherapy, INTERVIROLOGY, 49(6), 352-361, 2006
  603. Nuclear and mitochondrial DNA microsatellite instability in gastrointestinal stromal tumors, PATHOBIOLOGY, 73(2), 93-97, 2006
  604. Prolonged negative HCV-RNA status led to a good outcome in chronic hepatitis C patients with genotype 1b and super-high viral load, INTERVIROLOGY, 49(6), 362-369, 2006
  605. Successive, rapid recurrences of in-stent restenoses in a woman with angina pectoris, INTERNAL MEDICINE, 45(19), 1093-1096, 2006
  606. Cardiac glands hyperplastic polyp of the stomach, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(9), 1461-1463, SEP 2005
  607. A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5 ' flanking region of SMYD3 is a risk factor for human cancers, NATURE GENETICS, 37(10), 1104-1107, OCT 2005
  608. Adrenomedullin causes coronary vasodilation in humans - Effects of inhibition of nitric oxide synthesis, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 46(4), 534-539, OCT 2005
  609. Diagnostic ability of high-frequency ultrasound probe sonography in staging early gastric cancer, especially for submucosal invasion, ABDOMINAL IMAGING, 30(5), 518-523, OCT 2005
  610. Relationship between endothelial function in the coronary and brachial arteries, CLINICAL CARDIOLOGY, 28(10), 460-466, OCT 2005
  611. Therapeutic effect of repeated natural killer T cell stimulation in mouse cholangitis complicated by colitis, DIGESTIVE DISEASES AND SCIENCES, 50(10), 1844-1851, OCT 2005
  612. Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus, HEPATOLOGY, 42(5), 1046-1054, NOV 2005
  613. Reliable and cost-effective screening of inherited heterozygosity by Zn2+-cyclen polyacrylamide gel electrophoresis, CLINICAL CHEMISTRY, 51(11), 2195-2198, NOV 2005
  614. Somatic mutations of mitochondrial DNA in digestive tract cancers, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(11), 1679-1684, NOV 2005
  615. Monocyte chemoattractant protein-1 transfection induces angiogenesis and tumorigenesis of gastric carcinoma in nude mice via macrophage recruitment, CLINICAL CANCER RESEARCH, 11(21), 7629-7636, NOV 1 2005
  616. Role of the JNK pathway in thrombin-induced ICAM-1 expression in endothelial cells, CARDIOVASCULAR RESEARCH, 68(2), 289-298, NOV 1 2005
  617. Angiotensin II participates in hepatic inflammation and fibrosis through MCP-1 expression, DIGESTIVE DISEASES AND SCIENCES, 50(5), 942-948, MAY 2005
  618. Clinical features of gastric cancer discovered after successful eradication of Helicobacter pylori: results from a 9-year prospective follow-up study in Japan, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21(9), 1121-1126, MAY 1 2005
  619. Involvement of proinflammatory cytokines IL-1 beta and IL-6 in progression of human gastric carcinoma, ANTICANCER RESEARCH, 25(2A), 709-713, MAR-APR 2005
  620. A nuclear receptor ligand down-regulates cytosolic phospholipase A(2) expression to reduce bile acid-induced cyclooxygenase 2 activity in cholangiocytes: Implications of anticarcinogenic action of farnesoid X receptor agonists, DIGESTIVE DISEASES AND SCIENCES, 50(3), 514-524, MAR 2005
  621. G to A hypermutation of hepatitis B virus, HEPATOLOGY, 41(3), 626-633, MAR 2005
  622. Ubquitin-interacting motifs of epsin are involved in the regulation of insulin-dependent endocytosis, JOURNAL OF BIOCHEMISTRY, 137(3), 355-364, MAR 2005
  623. Morphological changes in human gastric tumours after eradication therapy of Helicobacter pylori in a short-term follow-up, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21(5), 559-566, MAR 1 2005
  624. Effect of famotidine on recurrent bleeding after successful endoscopic treatment of bleeding peptic ulcer, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21, 73-78, JUN 2005
  625. Effect of long-term half-dose famotidine therapy on corpus gastritis in peptic ulcer disease, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21, 99-104, JUN 2005
  626. Quantitative analysis of lymphangiogenic markers for predicting metastasis of human gastric carcinoma to lymph nodes, INTERNATIONAL JOURNAL OF CANCER, 115(3), 388-392, JUN 20 2005
  627. Hepatitis C virus core protein modulates fatty acid metabolism and thereby causes lipid accumulation in the liver, DIGESTIVE DISEASES AND SCIENCES, 50(7), 1361-1371, JUL 2005
  628. A case of congenital absence of the portal vein, HEPATOLOGY RESEARCH, 31(1), 43-47, JAN 2005
  629. A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer, JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 131(1), 19-25, JAN 2005
  630. Eradication of Helicobacter pylori increases the incidence of hyperlipidaemia and obesity in peptic ulcer patients, DIGESTIVE AND LIVER DISEASE, 37(1), 39-43, JAN 2005
  631. Infliximab therapy for Crohn's disease in a patient with chronic hepatitis B, DIGESTIVE DISEASES AND SCIENCES, 50(1), 163-166, JAN 2005
  632. Molecular evolutionary analyses implicate injection treatment for schistosomiasis in the initial hepatitis C epidemics in Japan, JOURNAL OF HEPATOLOGY, 42(1), 47-53, JAN 2005
  633. Single dose of OCH improves mucosal T helper type 1/T helper type 2 cytokine balance and prevents experimental colitis in the presence of v alpha 14 natural killer T cells in mice, INFLAMMATORY BOWEL DISEASES, 11(1), 35-41, JAN 2005
  634. Suppression of macrophage infiltration inhibits activation of hepatic stellate cells and liver fibrogenesis in rats, GASTROENTEROLOGY, 128(1), 138-146, JAN 2005
  635. Vascular function in patients with lower extremity peripheral arterial disease: a comparison of functions in upper and lower extremities, ATHEROSCLEROSIS, 178(1), 179-185, JAN 2005
  636. Biphasic effect of HMG-CoA reductase inhibitor, pitavastatin, on vascular endothelial cells and angiogenesis, CIRCULATION JOURNAL, 69(12), 1547-1555, DEC 2005
  637. Smoking, endothelial function, and Rho-kinase in humans, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 25(12), 2630-2635, DEC 2005
  638. Glycochenodeoxycholate plays a carcinogenic role in immortalized mouse cholanglocytes via oxidative DNA damage, FREE RADICAL BIOLOGY AND MEDICINE, 39(11), 1418-1427, DEC 1 2005
  639. Expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in early gastric carcinoma: correlation with clinicopathological parameters, CANCER LETTERS, 226(1), 85-90, AUG 8 2005
  640. A nuclear receptor-mediated choleretic action of fibrates is associated with enhanced canalicular membrane fluidity and transporter activity mediating bile acid-independent bile secretion, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 12(4), 211-217, AUG 25 2005
  641. A combination of the Helicobacter pylori stool antigen test and urea breath test is useful for clinical evaluation of eradication therapy: A multicenter study, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(8), 1241-1245, AUG 2005
  642. Multiple carcinoid tumors of the ileum preoperatively diagnosed by enteroscopy with the double-balloon technique, GASTROINTESTINAL ENDOSCOPY, 62(2), 315-318, AUG 2005
  643. The nicorandil-induced vasodilation in humans is inhibited by miconazole, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 45(4), 290-294, APR 2005
  644. Expression of p53 protein in esophageal squamous cell carcinoma: relation to hypoxia-inducible factor-1alpha, angiogenesis and apoptosis., Pathobiology, 72, 179-185, 20050901
  645. Ablation of ventricular tachycardia originating from the right ventricle associated with scleroderma cardiomyopathy., J Arrhythmia, 21(5), 542-545, 20050401
  646. Angiotensin II type I receptor blocker and endothelial function in humans: role of nitric oxide and oxidative stress., Curr.Med.Chem, 3(2), 133-148, 20050401
  647. Relationship between histopathological features and type V pit pattern determined by magnifying videocolonoscopy in early colorectal carcinoma, Dig Endos, 17, 117-122, 20050401
  648. Effects of angiotensin II on the expression of MCP-1 in hepatic stellate line LI90, Japanese Pharmaology and Therapeutics, 32, 143-5, 20050201
  649. Molecular evolutionaly analyses implicate injecthion treatment for schistosomiasis in the initial hepatitis C epidemics in japan, Journal of Hepatology, 42, 47-53, 20050101
  650. Superficial type serrated adenoma in ulcerative colitis resected by endoscopic submucosal dissection, Dig Endosc, 17, S49-S52, 20050101
  651. A classification system of echogenicity for gastrointestinal neoplasms, DIGESTION, 72(1), 8-12, 2005
  652. Expression of p53 protein in esophageal squamous cell carcinoma: Relation to hypoxia-inducible factor-1 alpha, angiogenesis and apoptosis, PATHOBIOLOGY, 72(4), 179-185, 2005
  653. Loss of heterozygosity on chromosome 10p14-p15 in colorectal carcinoma, PATHOBIOLOGY, 72(4), 220-224, 2005
  654. Improvement of atrial signal-averaged electrocardiographic abnormalities after radiofrequency catheter ablation in persistent atrial flutter, JAPANESE HEART JOURNAL, 45(5), 761-770, SEP 2004
  655. Concise prediction models of anticancer efficacy of 8 drugs using expression data from 12 selected genes, INTERNATIONAL JOURNAL OF CANCER, 111(4), 617-626, SEP 10 2004
  656. Partial characterization of cytoprotective mechanisms of lecithin against bile salt-induced bile duct damage, JOURNAL OF GASTROENTEROLOGY, 39(10), 955-960, OCT 2004
  657. Effect of edaravone, a novel free radical scavenger, on endothelium-dependent vasodilation in smokers, AMERICAN JOURNAL OF CARDIOLOGY, 94(8), 1070-1073, OCT 15 2004
  658. Apolipoprotein E phenotype affects the malondialdehyde-modified LDL concentration and forearm endothelial function in postmenopausal women, CLINICAL ENDOCRINOLOGY, 61(5), 619-625, NOV 2004
  659. Magnifying colonoscopic features of ulcerative colitis reflect histologic inflammation, INFLAMMATORY BOWEL DISEASES, 10(6), 737-744, NOV 2004
  660. Single nucleotide polymorphism in the hypoxia-inducible factor-1 alpha gene in colorectal carcinoma, ONCOLOGY REPORTS, 12(5), 1033-1037, NOV 2004
  661. A single nucleotide polymorphism in the MMP-1 promoter is correlated with histological differentiation of gastric cancer, JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 130(5), 259-265, MAY 2004
  662. Matrix metalloproteinase-9 contributes to human atrial remodeling during atrial fibrillation, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 43(5), 818-825, MAR 3 2004
  663. A case of latent primary biliary cirrhosis, HEPATOLOGY RESEARCH, 28(3), 166-169, MAR 2004
  664. Atrial contraction after surgical isolation of the left atrial posterior wall concomitant with mitral valve replacement, CIRCULATION JOURNAL, 68(3), 204-207, MAR 2004
  665. Clinical significance of angiopoietin-2 expression at the deepest invasive tumor site of advanced colorectal carcinoma, INTERNATIONAL JOURNAL OF ONCOLOGY, 24(3), 539-547, MAR 2004
  666. Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia, CIRCULATION, 109(10), 1215-1218, MAR 16 2004
  667. Fas and Fas ligand: Expression and soluble circulating levels in bile duct carcinoma, ONCOLOGY REPORTS, 11(6), 1183-1186, JUN 2004
  668. Initial experience with catheter probe US when using a multibending endoscope, GASTROINTESTINAL ENDOSCOPY, 59(7), 889-894, JUN 2004
  669. Induction of apoptosis by ionizing radiation and CI-1033 in HuCCT-1 cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 319(1), 114-119, JUN 18 2004
  670. Chronic gastritis with expression of inducible nitric oxide synthase is associated with high expression of interleukin-6 and hypergastrinaemia, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 19(12), 1309-1314, JUN 15 2004
  671. Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma, INTERNATIONAL JOURNAL OF CANCER, 110(2), 212-218, JUN 10 2004
  672. Chromosomal and microsatellite instability in sporadic gastric cancer, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 19(7), 756-760, JUL 2004
  673. Regulation of vascular endothelial growth factor (VEGF)-C and VEGF-D expression by the organ microenvironment in human colon carcinoma, EUROPEAN JOURNAL OF CANCER, 40(10), 1604-1609, JUL 2004
  674. Relation between C reactive protein concentrations and coronary microvascular endothelial function, HEART, 90(7), 750-754, JUL 2004
  675. Expression of human telomerase reverse transcriptase mRNA in esophageal cancers and precancerous lesions, ONCOLOGY REPORTS, 11(1), 51-55, JAN 2004
  676. Expression of VEGF-C and VEGF-D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma, CANCER SCIENCE, 95(1), 32-39, JAN 2004
  677. Gemcitabine suppresses malignant ascites of human pancreatic cancer: Correlation with VEGF expression in ascites, ONCOLOGY REPORTS, 11(1), 73-80, JAN 2004
  678. Angiogenic switch occurs during the precancerous stage of human esophageal squamous cell carcinoma, ONCOLOGY REPORTS, 11(2), 315-319, FEB 2004
  679. Clinicopathologic and endoscopic features of colorectal serrated adenoma: differences between polypoid and superficial types, GASTROINTESTINAL ENDOSCOPY, 59(2), 213-219, FEB 2004
  680. Mutation of the von Hippel-Lindau (VHL) gene in human colorectal carcinoma: Association with cytoplasmic accumulation of hypoxia-inducible factor (HIF)-1 alpha, CANCER SCIENCE, 95(2), 149-153, FEB 2004
  681. Epigenetic inactivation of SOCS-1 by CpG island hypermethylation in human gastric carcinoma, INTERNATIONAL JOURNAL OF CANCER, 112(6), 1003-1009, DEC 20 2004
  682. Expression of hypoxia-inducible factor (HIF)-1 alpha is associated with vascular endothelial growth factor expression and tumour anglogenesis in human oesophageal squamous cell carcinoma, EUROPEAN JOURNAL OF CANCER, 40(12), 1904-1912, AUG 2004
  683. Frequent loss of heterozygosity on chromosome 10p14-p15 in esophageal dysplasia and squamous cell carcinoma, ONCOLOGY REPORTS, 12(2), 333-337, AUG 2004
  684. Immune response in mouse experimental cholangitis associated with colitis induced by dextran sulfate sodium, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 19(8), 910-915, AUG 2004
  685. Identification of rare polymerase variants of hepatitis B virus using a two-stage PCR with peptide nucleic acid clamping, JOURNAL OF MEDICAL VIROLOGY, 72(4), 558-565, APR 2004
  686. Magnifying gastroendoscopy for diagnosis of histologic gastritis in the gastric antrum, DIGESTIVE AND LIVER DISEASE, 36(4), 286-291, APR 2004
  687. Sonographic detection of longitudinal ulcers in Crohn disease, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 39(4), 322-326, APR 2004
  688. Expression of hypoxia-inducible factor (HIF)-1alpha is associated with vascular endothelial growth factor expression and tumour angiogenesis in human oesophageal squamous cell carcinoma., Eur J Cancer, 40, 1904-1912, 20040801
  689. Relationship between C-reactive protein concetrations and coronary microvascular endothelial function0, Heart, 90, 750-754, 20040701
  690. Effects of aged garlic extract (AGE) on colorectal adenomas: a double-blinded study, Hiroshima J Med Sci, 53(3--4), 39-45, 20040401
  691. Pathophysiology of nonalcoholic steatohepatitis (NASH)-Relation to adipocytokine and advanced glycation end products., Japanese Pharmaology & Therapeutics, 32, 107-9, 20040201
  692. Clinical usefulness of high-frequency ultrasound probes for new invasion depth diagnosis in submucosal colorectal carcinoma, Dig Endosc, 16, S49-S52, 20040101
  693. Characteristics and trends of clarithromycin-resistant Helicobacter pylori isolates in Japan over a decade, PATHOBIOLOGY, 71(3), 159-163, 2004
  694. Frequent loss of RUNX3 expression by promoter hypermethylation in gastric carcinoma, PATHOBIOLOGY, 71(3), 137-143, 2004
  695. Mucin phenotype and background mucosa of intramucosal differentiated-type adenocarcinoma of the stomach, ONCOLOGY, 66(5), 379-387, 2004
  696. Frequent loss of heterozygosity on chromosome 10p15, a putative telomerase repressor/senescence gene locus, in gastric cancer, ONCOLOGY REPORTS, 10(5), 1297-1299, SEP-OCT 2003
  697. Prognostic value of p53 and Ki-67 expression in resected or biopsy specimens of bile duct carcinoma, ONCOLOGY REPORTS, 10(5), 1091-1096, SEP-OCT 2003
  698. Does intragastric nitrite concentration reflect gastric carcinogenesis in Japanese Helicobacter pylori-infected patients?, DIGESTIVE DISEASES AND SCIENCES, 48(9), 1730-1736, SEP 2003
  699. Gastric juice nitrite and vitamin C in patients with gastric cancer and atrophic gastritis: is low acidity solely responsible for cancer risk?, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 15(9), 987-993, SEP 2003
  700. Necessity of multiple gastric biopsies from different sites for detection of clarithromycin-resistant Helicobacter pylori strains, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(9), 942-946, SEP 2003
  701. p53 expression, K-ras gene mutation and microsatellite instability in gastric B-cell lymphomas, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 18(9), 1047-1053, SEP 2003
  702. Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 12(4), 437-442, OCT 2003
  703. Clinical significance of thrombospondin-1 expression in relation to vascular endothelial growth factor and interleukin-10 expression at the deepest invasive tumor site of advanced colorectal carcinoma, INTERNATIONAL JOURNAL OF ONCOLOGY, 23(4), 901-911, OCT 2003
  704. Disruption of the type 2 dopamine receptor gene causes a sodium-dependent increase in blood pressure in mice, AMERICAN JOURNAL OF HYPERTENSION, 16(10), 853-858, OCT 2003
  705. Prevalence of Helicobacter pylori resistance to clarithromycin and metronidazole determined by 23S ribosomal RNA and rdxA gene analyses in Hiroshima, Japan, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 18(10), 1202-1207, OCT 2003
  706. The promoter methylation status of the DNA repair gene O-6-methylguanine-DNA methyltransferase in ulcerative colitis, VIRCHOWS ARCHIV, 443(4), 518-523, OCT 2003
  707. Clinicopathologic features and endoscopic resection of early primary nonampullary duodenal carcinoma, JOURNAL OF CLINICAL GASTROENTEROLOGY, 37(5), 381-386, NOV-DEC 2003
  708. Somatic mutation in mitochondrial DNA and nuclear microsatellite instability in gastric cancer, ONCOLOGY REPORTS, 10(6), 1837-1841, NOV-DEC 2003
  709. Helicobacter pylori infection influences expression of genes related to angiogenesis and invasion in human gastric carcinoma cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 311(4), 809-814, NOV 28 2003
  710. Expressions of angiogenic factors in pancreatic ductal carcinoma: A correlative study with clinicopathologic parameters and patient survival, PANCREAS, 26(4), 344-349, MAY 2003
  711. Nodular gastritis in adults is caused by Helicobacter pylori infection, DIGESTIVE DISEASES AND SCIENCES, 48(5), 968-975, MAY 2003
  712. PDE5 inhibitor sildenafil citrate augments endothelium-dependent vasodilation in smokers, HYPERTENSION, 41(5), 1106-1110, MAY 2003
  713. Smoking activates Rho-kinase in smooth muscle cells of forearm vasculature in humans, HYPERTENSION, 41(5), 1102-1105, MAY 2003
  714. A comparison of low-dose and standard-dose oral estrogen on forearm endothelial function in early postmenopausal women, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 88(3), 1303-1309, MAR 2003
  715. Choleretic action of diosgenin is based upon the increases in canalicular membrane fluidity and transporter activity mediating bile acid independent bile flow, HEPATOLOGY RESEARCH, 25(3), 287-295, MAR 2003
  716. Giant gastric folds: Differential diagnosis at US, RADIOLOGY, 226(3), 686-690, MAR 2003
  717. Screening of genes specifically activated in the pancreatic juice ductal cells from the patients with pancreatic ductal carcinoma, CANCER SCIENCE, 94(3), 263-270, MAR 2003
  718. Unique reciprocal changes of hepatocellular membrane transporter expression and fluidity in rats with selective biliary obstruction, HEPATOLOGY RESEARCH, 26(2), 157-163, JUN 2003
  719. Long-term observation of reflux oesophagitis developing after Helicobacter pylori eradication therapy, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 17(12), 1529-1534, JUN 15 2003
  720. Expression of hypoxia-inducible factor-l alpha is associated with tumor vascularization in human colorectal carcinoma, INTERNATIONAL JOURNAL OF CANCER, 105(2), 176-181, JUN 10 2003
  721. Inhibition of cholesterol crystallization under bilirubin deconjugation: partial characterization of mechanisms whereby infected bile accelerates pigment stone formation, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1632(1-2), 48-54, JUN 10 2003
  722. Expression of fibroblast growth factor receptor genes in human hepatoma-derived cell lines, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 39(7), 321-328, JUL-AUG 2003
  723. Hypoxia-inducible factor-1 alpha expression and angiogenesis in gastrointestinal stromal tumor of the stomach, ONCOLOGY REPORTS, 10(4), 797-802, JUL-AUG 2003
  724. Natural histories of hepatitis C virus infection in men and women simulated by the Markov model, JOURNAL OF MEDICAL VIROLOGY, 70(3), 378-386, JUL 2003
  725. The specific expression of Hypoxia Inducible Factor-1 alpha in human gastric mucosa induced by nonsteroidal anti-inflammatory drugs, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 18, 90-98, JUL 2003
  726. Low body mass index is a risk factor for impaired endothelium-dependent vasodilation in humans: Role of nitric oxide and oxidative stress, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 42(2), 256-263, JUL 16 2003
  727. Food deprivation enhances somatostatin and somatostatin receptor subtype expression in rat colon, REGULATORY PEPTIDES, 114(2-3), 167-173, JUL 15 2003
  728. Cardiac angiotensin II type 2 receptor activates the kinin/NO system and inhibits fibrosis, HYPERTENSION, 41(1), 99-107, JAN 2003
  729. Hydrophilic bile salts have a cytoprotective effect against cyclosporine A-induced cholestasis through enhanced canalicular membrane fluidity and transporter activity, HEPATOLOGY RESEARCH, 25(1), 38-47, JAN 2003
  730. Autonomic nerve dysfunction is closely associated with the abnormalities of esophageal motility in reflux esophagitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(2), 159-163, FEB 2003
  731. Helicobacter pylori infection influences tumor growth of human gastric carcinomas, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(2), 153-158, FEB 2003
  732. Impaired gallbladder mucosal function in aged gallstone patients suppresses gallstone recurrence after successful extracorporeal shockwave lithotripsy, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 18(2), 157-161, FEB 2003
  733. Leptin causes nitric-oxide independent coronary artery vasodilation in humans, HYPERTENSION RESEARCH, 26(2), 147-152, FEB 2003
  734. Small rectal carcinoid with lymph node metastasis diagnosed prior to treatment, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 15(2), 195-197, FEB 2003
  735. Promoter methylation of cyclin D2 gene in gastric carcinoma, INTERNATIONAL JOURNAL OF ONCOLOGY, 23(6), 1663-1670, DEC 2003
  736. Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes, DIGESTIVE DISEASES AND SCIENCES, 48(12), 2315-2322, DEC 2003
  737. Response of the left anterior descending coronary artery to Acetylcholine in patients with chest pain and angiographically normal coronary arteries, AMERICAN JOURNAL OF CARDIOLOGY, 92(12), 1394-1398, DEC 15 2003
  738. Mnk1 is required for angiotensin II - Induced protein synthesis in vascular smooth muscle cells, CIRCULATION RESEARCH, 93(12), 1218-1224, DEC 12 2003
  739. Effect of different intensities of exercise on endothelium-dependent vasodilation in humans - Role of endothelium-dependent nitric oxide and oxidative stress, CIRCULATION, 108(5), 530-535, AUG 5 2003
  740. Impact of aging on the development of hepatocellular carcinoma in patients with hepatitis C virus infection in Japan, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(8), 894-900, AUG 2003
  741. Myocardial bridging increases the risk of coronary spasm, CLINICAL CARDIOLOGY, 26(8), 377-383, AUG 2003
  742. Somatic mutation of mitochondrial DNA in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 12(2), 169-174, AUG 2003
  743. AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl4, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 308(1), 177-183, AUG 15 2003
  744. Comparison of forearm endothelial function between premenopausal and postmenopausal women with or without hypercholesterolemia, MATURITAS, 44(4), 307-315, APR 25 2003
  745. Isolated granulomatous gastritis successfully treated by Helicobacter pylori eradication: a possible association between granulomatous gastritis and Helicobacter pylori, JOURNAL OF GASTROENTEROLOGY, 38(4), 371-375, APR 2003
  746. Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human gastric carcinomas, INTERNATIONAL JOURNAL OF ONCOLOGY, 22(4), 773-778, APR 2003
  747. Potential involvement of IL-8 and its receptors in the invasiveness of pancreatic cancer cells, INTERNATIONAL JOURNAL OF ONCOLOGY, 22(4), 765-771, APR 2003
  748. Serum pepsinogen concentration as a marker of Helicobacter pylori infection and the histologic grade of gastritis; evaluation of gastric mucosa by serum pepsinogen levels, JOURNAL OF GASTROENTEROLOGY, 38(4), 332-338, APR 2003
  749. Significance of an exaggerated meal-stimulated gastrin response in pathogenesis of Helicobacter pylori-negative duodenal ulcer, DIGESTIVE DISEASES AND SCIENCES, 48(4), 644-651, APR 2003
  750. Depressed-type, early duodenal carcinoma(carcinoma in situ) treated by endoscopic mucosal resection, J. Gastroenterol., 38(8), 813-815, 20030401
  751. Expression of hyposia-inducible factor-1 alpha is associated with tumor vascularization in human colorectal carcinoma, Int J Cancer, 105(2), 176-181, 20030401
  752. Expression of vascular endothelial growth facter and angiogenesis in gastrointestinal stromal tumor of the stomach, Oncology, 64(3), 266-274, 20030401
  753. Minute depressed colon cancer with submucosal invasion, Gastrointest Endosc, 57(4), 564-565, 20030401
  754. Nondular gastritis in adults is caused by Helicobacter pylori ingfection, Dig Dis Sci, 48(5), 968-975, 20030401
  755. Prominent J wave and ST segment elevation: Serial electrocardiographic changes in accidental hypothermia, Journal of cardiovasuclar electrophysiology, 14(2), 223, 20030401
  756. Clinical significance of angiogenic factor expression at the deepest invasive site of advanced colorectal carcinoma, ONCOLOGY, 64(1), 61-73, 2003
  757. Expression of vascular endothelial growth factor and angiogenesis in gastrointestinal stromal tumor of the stomach, ONCOLOGY, 64(3), 266-274, 2003
  758. Rare quasispecies in the YMDD motif of hepatitis B virus detected by polymerase chain reaction with peptide nucleic acid clamping, INTERVIROLOGY, 46(6), 355-361, 2003
  759. Combination therapy of low-dose medroxyprogesterone acetate and oral estrogen does not affect endothelial function in the forearms of postmenopausal women, MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 9(5), 360-366, SEP-OCT 2002
  760. Determining depth of invasion by VN pit pattern analysis in submucosal colorectal carcinoma, ONCOLOGY REPORTS, 9(5), 1005-1008, SEP-OCT 2002
  761. Clinical characteristics and natural history of patients with low-grade reflux esophagitis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 17(9), 949-954, SEP 2002
  762. Combination of transcatheter arterial chemoembolization using cisplatin-lipiodol suspension and percutaneous ethanol injection for treatment of advanced small hepatocellular carcinoma, AMERICAN JOURNAL OF SURGERY, 184(3), 284-290, SEP 2002
  763. Nicorandil-induced preconditioning as evidenced by troponin T measurements after coronary angioplasty in patients with stable angina pectoris, JAPANESE HEART JOURNAL, 43(5), 443-453, SEP 2002
  764. Hormone replacement effects on endothelial function measured in the forearm resistance artery in normocholesterolemic and hypercholesterolemic postmenopausal women, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 87(10), 4634-4641, OCT 2002
  765. Human telomerase reverse transcriptase, p53 and Ki-67 expression and apoptosis in colorectal serrated adenoma, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(10), 1194-1200, OCT 2002
  766. Effect of alcohol consumption on endothelial function in men with coronary artery disease, ATHEROSCLEROSIS, 165(1), 145-152, NOV 2002
  767. Irsogladine malate up-regulates gap junctional intercellular communication between pancreatic cancer cells via PKA pathway, PANCREAS, 25(4), 373-377, NOV 2002
  768. Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human esophageal squamous cell carcinomas, INTERNATIONAL JOURNAL OF CANCER, 102(3), 220-224, NOV 20 2002
  769. Clinical significance of angiogenesis in rectal carcinoid tumors, ONCOLOGY REPORTS, 9(3), 489-494, MAY-JUN 2002
  770. Balloon-occluded retrograde transvenous obliteration of gastric fundal varices with hemorrhage, AMERICAN JOURNAL OF ROENTGENOLOGY, 178(5), 1167-1174, MAY 2002
  771. Implication of anti-parietal cell antibody levels in gastrointestinal diseases, including gastric carcinogenesis, DIGESTIVE DISEASES AND SCIENCES, 47(5), 1080-1085, MAY 2002
  772. Preoperative assessment of gastric cancer vascularity by flash echo imaging, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(5), 608-612, MAY 2002
  773. Severity of hypertension affects improved resistance artery endothelial function by angiotensin-converting enzyme inhibition, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 39(5), 668-676, MAY 2002
  774. Cigarette smoking promotes atrophic gastritis in Helicobacter pylori-positive subjects, DIGESTIVE DISEASES AND SCIENCES, 47(3), 675-681, MAR 2002
  775. Leptin causes vasodilation in humans, HYPERTENSION RESEARCH, 25(2), 161-165, MAR 2002
  776. Role of anti-parietal cell antibody in Helicobacter pylori-associated atrophic gastritis: Evaluation in a country of high prevalence of atrophic gastritis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(3), 287-293, MAR 2002
  777. Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia, HEART, 87(3), 264-269, MAR 2002
  778. Management of chronic hepatitis C and prevention of hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY, 37, 69-73, JUN 2002
  779. Endothelial function and oxidative stress in renovascular hypertension, NEW ENGLAND JOURNAL OF MEDICINE, 346(25), 1954-1962, JUN 20 2002
  780. Evaluation of esophageal motility by endosonography using a miniature ultrasonographic probe in patients with reflux esophagitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(6), 674-678, JUN 1 2002
  781. Evaluation of gastric emptying measured with the C-13-octanoic acid breath test in patients with functional dyspepsia comparison with ultrasonography, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(6), 662-666, JUN 1 2002
  782. Preconditioning effect during coronary angioplasty in patients with stable angina pectoris, INTERNAL MEDICINE, 41(7), 509-515, JUL 2002
  783. Vascular endothelial growth factor-C expression predicts lymph node metastasis of human gastric carcinomas invading the submucosa, EUROPEAN JOURNAL OF CANCER, 38(10), 1413-1419, JUL 2002
  784. p53 codon 72 polymorphism in gastric cancer susceptibility in patients with Helicobacter pylori-associated chronic gastritis, INTERNATIONAL JOURNAL OF CANCER, 100(3), 304-308, JUL 20 2002
  785. Renal endothelial dysfunction and hypertension, JOURNAL OF DIABETES AND ITS COMPLICATIONS, 16(1), 103-107, JAN-FEB 2002
  786. Tetrahydrobiopterin improves coronary endothelial function, but does not prevent coronary spasm in patients with vasospastic angina, CIRCULATION JOURNAL, 66(1), 58-62, JAN 2002
  787. Excess norepinephrine impairs both endothelium-dependent and -independent vasodilation in patients with pheochromocytoma, HYPERTENSION, 39(2), 513-518, FEB 2002
  788. Helicobacter pylori infection increases serum nitrate and nitrite more prominently than serum pepsinogens, HELICOBACTER, 7(1), 9-13, FEB 2002
  789. Serological comparison of serum pepsinogen and antiparietal cell antibody levels between Japanese and German patients, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 14(2), 123-127, FEB 2002
  790. Estrogen replacement suppresses function of thrombin stimulated platelets by inhibiting Ca2+ influx and raising cyclic adenosine monophosphate, CARDIOVASCULAR RESEARCH, 53(3), 634-641, FEB 15 2002
  791. Less hydrophobic phosphatidylcholine species simplify biliary vesicle morphology, but induce bile metastability with a broad spectrum of crystal forms, BIOCHEMICAL JOURNAL, 362, 105-112, FEB 15 2002
  792. K-ras mutation in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer, INTERNATIONAL JOURNAL OF CANCER, 97(5), 562-566, FEB 10 2002
  793. Circadian variation of blood pressure and endothelial function in patients with essential hypertension: A comparison of dippers and non-dippers, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 40(11), 2039-2043, DEC 4 2002
  794. A frameshift mutation of beta subunit of epithelial sodium channel in a case of isolated Liddle syndrome, JOURNAL OF HYPERTENSION, 20(12), 2379-2382, DEC 2002
  795. Mechanisms responsible for vasodilation upon magnesium infusion in vivo: Clinical evidence, MAGNESIUM RESEARCH, 15(3-4), 241-246, DEC 2002
  796. Advanced colorectal carcinoma smaller than 10 mm in maximum diameter with special reference to clinicopathologic and molecular features: a report of 3 cases, GASTROINTESTINAL ENDOSCOPY, 56(2), 299-303, AUG 2002
  797. Helicobacter pylori eradication therapy improves atrophic gastritis and intestinal metaplasia: a 5-year prospective study of patients with atrophic gastritis, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 16(8), 1449-1456, AUG 2002
  798. A low-calorie diet improves endothelium-dependent vasodilation in obese patients with essential hypertension, AMERICAN JOURNAL OF HYPERTENSION, 15(4), 302-309, APR 2002
  799. High incidence of B-cell monoclonality in follicular gastritis: a possible association between follicular gastritis and MALT lymphoma, VIRCHOWS ARCHIV, 440(4), 376-380, APR 2002
  800. Long-term rebamipide therapy improves Helicobacter pylori-associated chronic gastritis, DIGESTIVE DISEASES AND SCIENCES, 47(4), 862-867, APR 2002
  801. Nicorandil enhances myocardial tolerance to ischemia without progressive collateral recruitment during coronary angioplasty, CIRCULATION JOURNAL, 66(4), 317-322, APR 2002
  802. Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals, AMERICAN JOURNAL OF HYPERTENSION, 15(4), 326-332, APR 2002
  803. Hepatic hydroxylation of bile acids and chronic liver diseases: do transporters play a mechanistic role?, 20020401
  804. Single administration of ecabet sodium diminishes the level of delta-(13) Co(2) in urea breath test, J GastroenterolM., 37(8), 674-675, 20020401
  805. Clinical significance of vascular endothelial growth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma, ONCOLOGY, 62(2), 157-166, 2002
  806. Pathogenic significance and organic virus levels in patients infected with TT virus, INTERVIROLOGY, 44(5), 291-297, SEP-OCT 2001
  807. A low C-13-urea breath test value is associated with increased risk of gastric cancer, JOURNAL OF GASTROENTEROLOGY, 36(9), 601-605, SEP 2001
  808. Expression of telomeric repeat binding factor 1 and 2 and TRF1-interacting nuclear protein 2 in human gastric carcinomas, INTERNATIONAL JOURNAL OF ONCOLOGY, 19(3), 507-512, SEP 2001
  809. Randomized controlled clinical trial of lymphoblastoid interferon-alpha for chronic hepatitis C, HEPATOLOGY RESEARCH, 21(1), 55-66, SEP 2001
  810. Clinicopathological significance of vascular endothelial growth factor (VEGF)-C in human esophageal squamous cell carcinomas, INTERNATIONAL JOURNAL OF CANCER, 93(5), 662-666, SEP 1 2001
  811. Calorie restriction reduced blood pressure in obesity hypertensives by improvement of autonomic nerve activity and insulin sensitivity, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 38, S69-S74, OCT 2001
  812. Effect of obesity on endothelium-dependent, nitric oxide-mediated vasodilation in normotensive individuals and patients with essential hypertension, AMERICAN JOURNAL OF HYPERTENSION, 14(10), 1038-1045, OCT 2001
  813. MUC1 and cathepsin D expression in early colorectal carcinoma showing V type pit pattern, INTERNATIONAL JOURNAL OF ONCOLOGY, 19(4), 665-672, OCT 2001
  814. Extracorporeal ultrasound is an effective diagnostic alternative to endoscopic ultrasound for gastric submucosal tumours, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 36(11), 1222-1226, NOV 2001
  815. Sodium chloride loading does not alter endothelium-dependent vasodilation of forearm vasculature in either salt-sensitive or salt-resistant patients with essential hypertension, HYPERTENSION RESEARCH, 24(6), 711-716, NOV 2001
  816. Microsatellite instability is a genetic marker for the development of multiple gastric cancers, INTERNATIONAL JOURNAL OF CANCER, 95(6), 350-353, NOV 20 2001
  817. Usefulness of flow-mediated dilation of the brachial artery and/or the intima-media thickness of the carotid artery in predicting coronary narrowing in patients suspected of having coronary artery disease, AMERICAN JOURNAL OF CARDIOLOGY, 88(10), 1147-1151, NOV 15 2001
  818. Bile-salt hydrophobicity is a key factor regulating rat liver plasma-membrane communication: relation to bilayer structure, fluidity and transporter expression and function, BIOCHEMICAL JOURNAL, 359, 605-610, NOV 1 2001
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  820. Is a role of phospholipase A(2) in cholesterol gallstone formation phospholipid species-dependent?, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1532(1-2), 51-59, MAY 31 2001
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  822. c-myc gene mutation in gastric mucose-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphoma, ONCOLOGY REPORTS, 8(2), 289-292, MAR-APR 2001
  823. Microsatellite instability at D18S61 is associated with no regression of gastric mucosa-associated lymphoid tissue lymphoma after Helicobacter pylori eradication, ONCOLOGY REPORTS, 8(2), 293-297, MAR-APR 2001
  824. Cyclosporin A reduces canalicular membrane fluidity and regulates transporter function in rats, BIOCHEMICAL JOURNAL, 354, 591-596, MAR 15 2001
  825. Dose-dependent conjugation of sulfobromophthalein and hepatic transit time in bile fistula rats - Role of the microtubule-dependent vesicle pathway, DIGESTIVE DISEASES AND SCIENCES, 46(6), 1285-1289, JUN 2001
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  832. Lamivudine therapy for spontaneously occurring severe acute exacerbation in chronic hepatitis B virus infection: A preliminary study, AMERICAN JOURNAL OF GASTROENTEROLOGY, 96(2), 557-562, FEB 2001
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  835. Interleukin 8 and vascular endothelial growth factor - prognostic factors in human gastric carcinomas?, EUROPEAN JOURNAL OF CANCER, 37(12), 1482-1487, AUG 2001
  836. Nonselective cation channel as a Ca2+ influx pathway in pepsinogen-secreting cells of bullfrog esophagus, AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 281(2), G333-G341, AUG 2001
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  841. Efficacy of IFN therapy based on duration period of negative HCV-RNA during IFN administration, Hepatol Res, 19, 22-300, 20010401
  842. Long-term interferon therapy for 1 year or longer reduces the hepatocellular carcinogenesis rate in patients with liver cirrhosis caused by hepatitis C virus: a pilot study, J Gastroenterol Hepatol., 16(4), 406-415, 20010401
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  845. Activation of peroxisome proliferator-activated receptor gamma inhibits the growth of human pancreatic cancer, PATHOBIOLOGY, 69(5), 258-265, 2001
  846. Expression of MRE11 complex (MRE11, RAD50, NBS1) and hRap1 and its relation with telomere regulation, telomerase activity in human gastric carcinomas, PATHOBIOLOGY, 69(4), 219-224, 2001
  847. Association of amino acid sequence in the PKR-eIF2 phosphorylation homology domain and response to interferon therapy, HEPATOLOGY, 32(5), 1138-1144, NOV 2000
  848. Distinction between chronic hepatitis and liver cirrhosis in patients with hepatitis C virus infection. Practical discriminant function using common laboratory data, Hepatol Res, 18(3), 252-266, 20000401
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  851. Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor-A prospective randomized study of hepatitis C virus-related liver cancer., Hepatology, 32(2), 436-438, 20000401
  852. Progressive and sufficient decrease of hepatitis B core antibody can predict the disappearance of hepatitis B virus DNA in Japanese patients with hepatitis B surface antigen clearance, J. Gastroenterol., 35(10), 753-757, 20000401
  853. Relationship between five-year histological outcome and serial changes in serum alanine aminotransferase in patients with biochemical and virological relapse after interferon treatment for chronic hepatitis C, Intervirol, 43, 174-179, 20000401
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  857. Combined ursodeoxycholic acid glycyrrhizin therapy for chronic hepatitis C virus infection: a randomized controlled trial in 170 patients, Eur J Gastroen Hepat, 11, 1077-1083, 19990401
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  860. Efficacy and changes of the nonstructural 5A gene by prolonged interferon therapy for patients with hepatitis C virus (HCV) genotype1b and a high level of serum HCV-RNA, Intern Med, 38, 19990401
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  863. Histological changes in liver biopsies after one year of lamivudine treatment in patients with chronic hepatitis B infection, J Hepatol, 30, 743-748, 19990401
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  866. Time course of histological changes in patients with a sustained biochemical and virological response to corticosteroid withdrawal therapy for chronic hepatitis B, Am J Gastroenterol, 94, 3304-3309, 19990401
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  868. Biochemical and histological features of hepatitis G virus infection, J Gastroenterol Hepatol., 13, 767-772, 19980401
  869. Deletions in the hepatitis B virus core gene may influence the clinical outcome in hepatitis B e antigen-positive asymptomatic healthy carriers., Journal of Medical Virology, 56, 287-293, 19980401
  870. Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients, J Hepatol, 28, 930-938, 19980401
  871. Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy., Hepatology, 27, 1711-1716, 19980401
  872. Glomerulonephritis in autopsy cases with hepatitis C virus infection, Internal Med., 37(10), 836-840, 19980401
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  878. A prospective randomized administration of 5'-deoxy-5-fluorouridine as adjuvant chemotherapy for hepatocellular carcinoma treated with transcatheter arterial chemoembolization., Am. J. Clin. Oncol., 20(2), 202-208, 19970401
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  890. Typing six major hepatitis C virus genotypes by polymerase chain reaction using primers derived from nucleotide sequences of the NS5 region, Int Hepatol Commun, 4, 263-267, 19960401
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  895. Molecular analysis of intraspousal transmission of hepatitis C virus, J Hepatol, 22, 431-439, 19950401
  896. Novel hepatitis B variants in sibling carriers positive for antibody to hepatitis B surface antigen, Int Hepatol Commun, 4, 121-125, 19950401
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  920. Morbidly obese patient with non-alcoholic steatohepatitis-related cirrhosis who died from sepsis caused by dental infection of Porphyromonas gingivalis: A case report, HEPATOLOGY RESEARCH, 46(3), E210-E215, MAR 2016
  921. MicroRNAs as Biomarkers for Liver Disease and Hepatocellular Carcinoma, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 17(3), MAR 2016
  922. Functional Behavior of NKp46-Positive Intrahepatic Natural Killer Cells Against Hepatitis C Virus Reinfection After Liver Transplantation, TRANSPLANTATION, 100(2), 355-364, FEB 2016
  923. Mouse model of proximal colon-specific tumorigenesis driven by microsatellite instability-induced Cre-mediated inactivation of Apc and activation of Kras, JOURNAL OF GASTROENTEROLOGY, 51(5), 447-457, MAY 2016
  924. Clinical significance and validity of the subclassification for colorectal laterally spreading tumor granular type, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(5), 973-979, MAY 2016
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  927. Perinatal Resveratrol Supplementation to Spontaneously Hypertensive Rat Dams Mitigates the Development of Hypertension in Adult Offspring, HYPERTENSION, 67(5), 1045-1052, MAY 2016
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  931. CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 23(3), 309-319, 2016
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  935. Interleukin-34 as a fibroblast-derived marker of liver fibrosis in patients with non-alcoholic fatty liver disease, SCIENTIFIC REPORTS, 6, JUL 1 2016
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  937. Comparison of Outcome of Hepatic Arterial Infusion Chemotherapy and Sorafenib in Patients with Hepatocellular Carcinoma Refractory to Transcatheter Arterial Chemoembolization, ANTICANCER RESEARCH, 36(7), 3523-3529, JUL 2016
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  940. Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma, CANCER SCIENCE, 107(5), 601-608, MAY 2016
  941. HBV culture and infectious systems, HEPATOLOGY INTERNATIONAL, 10(4), 559-566, JUL 2016
  942. ADH1B and ALDH2 are associated with metachronous SCC after endoscopic submucosal dissection of esophageal squamous cell carcinoma, CANCER MEDICINE, 5(7), 1397-1404, JUL 2016
  943. Useful condition of chromoendoscopy with indigo carmine and acetic acid for identifying a demarcation line prior to endoscopic submucosal dissection for early gastric cancer, BMC GASTROENTEROLOGY, 16, JUL 19 2016
  944. Hepatitis C virus dynamics and cellular gene expression in uPA-SCID chimeric mice with humanized livers during intravenous silibinin monotherapy, JOURNAL OF VIRAL HEPATITIS, 23(9), 708-717, SEP 2016
  945. Daclatasvir and asunaprevir treatment improves liver function parameters and reduces liver fibrosis markers in chronic hepatitis C patients, HEPATOLOGY RESEARCH, 46(8), 758-764, JUL 2016
  946. Improvement of renal dysfunction in a patient with hepatitis C virus-related liver cirrhosis by daclatasvir and asunaprevir combination therapy: A case report, HEPATOLOGY RESEARCH, 46(9), 944-948, AUG 2016
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  948. Nitroglycerine-induced vasodilation in coronary and brachial arteries in patients with suspected coronary artery disease, INTERNATIONAL JOURNAL OF CARDIOLOGY, 219, 312-316, SEP 15 2016
  949. Three patients treated with daclatasvir and asunaprevir for recurrent hepatitis C after liver transplantation: Case report, HEPATOLOGY RESEARCH, 46(7), 707-712, JUN 2016
  950. RNA Exosome Complex Regulates Stability of the Hepatitis B Virus X-mRNA Transcript in a Non-stop-mediated (NSD) RNA Quality Control Mechanism, JOURNAL OF BIOLOGICAL CHEMISTRY, 291(31), 15958-15974, JUL 29 2016
  951. Preoperative Fluorine 18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography for Prediction of Microvascular Invasion in Small Hepatocellular Carcinoma, JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 40(4), 524-530, JUL-AUG 2016
  952. Long-term prognosis after endoscopic submucosal dissection for early gastric cancer in super-elderly patients, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 30(10), 4321-4329, OCT 2016
  953. Endoscopic submucosal dissection for anorectal tumor with hemorrhoids close to the dentate line: a multicenter study of Hiroshima GI Endoscopy Study Group, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 30(10), 4425-4431, OCT 2016
  954. Risk factors for esophageal stenosis after entire circumferential endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 30(9), 4049-4056, SEP 2016
  955. A MAVS/TICAM-1-Independent Interferon-Inducing Pathway Contributes to Regulation of Hepatitis B Virus Replication in the Mouse Hydrodynamic Injection Model, JOURNAL OF INNATE IMMUNITY, 7(1), 47-58, 2015
  956. Clinical impact of dual red imaging in colorectal endoscopic submucosal dissection: a pilot study, THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 9(5), 679-683, SEP 2016
  957. Serum YKL-40 as a marker of liver fibrosis in patients with non-alcoholic fatty liver disease, SCIENTIFIC REPORTS, 6, OCT 14 2016
  958. The Role of the Selective Arterial Secretagogue Injection Test for Non-Functional Pancreatic Neuroendocrine Tumor, JOURNAL OF THE PANCREAS, 16(6), 601-606, NOV 2015
  959. Characteristics of non-obese non-alcoholic fatty liver disease: Effect of genetic and environmental factors, HEPATOLOGY RESEARCH, 46(10), 1011-1018, SEP 2016
  960. Pharmacokinetics, efficacy and safety of daclatasvir plus asunaprevir in dialysis patients with chronic hepatitis C: pilot study, JOURNAL OF VIRAL HEPATITIS, 23(11), 850-856, NOV 2016
  961. Interferon-stimulated gene of 20 kDa protein (ISG20) degrades RNA of Hepatitis B virus to impede the replication of HBV in vitro and in vivo, ONCOTARGET, 7(42), 68179-68193, OCT 18 2016
  962. Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection, JOURNAL OF GASTROENTEROLOGY, 51(11), 1073-1080, NOV 2016
  963. Highly multiplexed CRISPR-Cas9-nuclease and Cas9-nickase vectors for inactivation of hepatitis B virus, GENES TO CELLS, 21(11), 1253-1262, NOV 2016
  964. Clinical usefulness of narrow band imaging magnifying colonoscopy for assessing ulcerative colitis-associated cancer/dysplasia, ENDOSCOPY INTERNATIONAL OPEN, 4(11), E1183-E1187, NOV 2016
  965. Third-Generation Capsule Endoscopy Outperforms Second-Generation Based on the Detectability of Esophageal Varices, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2016
  966. Vaniprevir plus peginterferon alfa-2b and ribavirin in treatment-experienced Japanese patients with hepatitis C virus genotype 1 (GT1b) infection: Phase 3 studies, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(10), 1674-1683, OCT 2016
  967. A comparison of 4-Fr with 5-Fr endoscopic nasopancreatic drainage catheters: A randomized, controlled trial, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(10), 1783-1789, OCT 2016
  968. Risk stratification of ventricular fibrillation in Brugada syndrome using noninvasive scoring methods, HEART RHYTHM, 13(10), 1947-1954, OCT 2016
  969. Effects of ITPA polymorphism on decrease of hemoglobin during simeprevir, peg-interferon, and ribavirin combination treatment for chronic hepatitis C, HEPATOLOGY RESEARCH, 46(12), 1256-1263, NOV 2016
  970. Combination therapies with daclatasvir and asunaprevir on NS3-D168 mutated HCV in human hepatocyte chimeric mice, ANTIVIRAL THERAPY, 21(4), 307-315, 2016
  971. Vascular Function and Intima-media Thickness of a Leg Artery in Peripheral Artery Disease: A Comparison of Buerger Disease and Atherosclerotic Peripheral Artery Disease, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 23(11), 1261-1269, 2016
  972. Genetic variations of aldehyde dehydrogenase 2 and alcohol dehydrogenase 1B are associated with the etiology of atrial fibrillation in Japanese, JOURNAL OF BIOMEDICAL SCIENCE, 23, DEC 7 2016
  973. Circulating level of pigment epithelium-derived factor is associated with vascular function and structure: A cross-sectional study, INTERNATIONAL JOURNAL OF CARDIOLOGY, 225, 91-95, DEC 15 2016
  974. Hepatitis C virus treatment update - A new era of all-oral HCV treatment, ADVANCES IN DIGESTIVE MEDICINE, 3(4), 153-160, DEC 2016
  975. Endothelial Function Assessed by Automatic Measurement of Enclosed Zone Flow-Mediated Vasodilation Using an Oscillometric Method Is an Independent Predictor of Cardiovascular Events, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 5(12), DEC 2016
  976. Choline Deficiency Causes Colonic Type II Natural Killer T (NKT) Cell Loss and Alleviates Murine Colitis under Type I NKT Cell Deficiency, PLOS ONE, 12(1), JAN 17 2017
  977. Protease Inhibitor Resistance Remains Even After Mutant Strains Become Undetectable by Deep Sequencing, JOURNAL OF INFECTIOUS DISEASES, 214(11), 1687-1694, DEC 1 2016
  978. Whole genome sequencing discriminates hepatocellular carcinoma with intrahepatic metastasis from multi-centric tumors, JOURNAL OF HEPATOLOGY, 66(2), 363-373, FEB 2017
  979. Evaluation for the Clinical Efficacy of Colon Capsule Endoscopy in the Detection of Laterally Spreading Tumors, DIGESTION, 95(1), 43-48, 2017
  980. The practical management of chronic hepatitis C infection in Japan - dual therapy of daclatasvir plus asunaprevir, EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 11(2), 103-113, FEB 2017
  981. Interferon Stimulated Genes and Innate Immune Activation Following Infection With Hepatitis B and C Viruses, JOURNAL OF MEDICAL VIROLOGY, 89(3), 388-396, MAR 2017
  982. Efficacy and Safety of Daclatasvir Plus Asunaprevir Therapy for Chronic Hepatitis C Patients With Renal Dysfunction, JOURNAL OF MEDICAL VIROLOGY, 89(4), 665-671, APR 2017
  983. Common Variant Near HEY2 Has a Protective Effect on Ventricular Fibrillation Occurrence in Brugada Syndrome by Regulating the Repolarization Current, CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 9(1), JAN 2016
  984. Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus, PLOS ONE, 12(3), MAR 2 2017
  985. Retrograde venography during balloon-occluded retrograde transvenous obliteration of gastric varices, MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES, 26(1), 1-6, 2017
  986. The relationship between HBcrAg and HBV reinfection in HBV related post-liver transplantation patients, JOURNAL OF GASTROENTEROLOGY, 52(3), 366-375, MAR 2017
  987. The risk of transient postprandial oxyhypoglycemia in nonalcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 52(2), 253-262, FEB 2017
  988. Daclatasvir/asunaprevir/beclabuvir fixed-dose combination in Japanese patients with HCV genotype 1 infection, JOURNAL OF GASTROENTEROLOGY, 52(3), 385-395, MAR 2017
  989. Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population, HUMAN MOLECULAR GENETICS, 26(3), 650-659, FEB 1 2017
  990. Quasispecies of Hepatitis C Virus Participate in Cell-Specific Infectivity, SCIENTIFIC REPORTS, 7, MAR 22 2017
  991. Long-term outcomes after endoscopic submucosal dissection for superficial colorectal tumors, GASTROINTESTINAL ENDOSCOPY, 85(3), 546-553, MAR 2017
  992. Real-world efficacy and safety of daclatasvir and asunaprevir therapy for hepatitis C virus-infected cirrhosis patients, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 32(3), 645-650, MAR 2017
  993. Endothelial dysfunction and abnormal vascular structure are simultaneously present in patients with heart failure with preserved ejection fraction, INTERNATIONAL JOURNAL OF CARDIOLOGY, 231, 181-187, MAR 15 2017
  994. Endothelial function is impaired in relation to alcohol intake even in the case of light alcohol consumption in Asian men; Flow-mediated Dilation Japan (FMD-J) Study, INTERNATIONAL JOURNAL OF CARDIOLOGY, 230, 523-528, MAR 1 2017
  995. IFNL4 polymorphism effects on outcome of simeprevir, peginterferon, and ribavirin therapy for older patients with genotype 1 chronic hepatitis C, HEPATOLOGY RESEARCH, 47(3), E5-E13, MAR 2017
  996. Safety and efficacy of dual therapy with daclatasvir and asunaprevir for older patients with chronic hepatitis C, JOURNAL OF GASTROENTEROLOGY, 52(4), 504-511, APR 2017
  997. The combination of elbasvir and grazoprevir for the treatment of chronic HCV infection in Japanese patients: a randomized phase II/III study, JOURNAL OF GASTROENTEROLOGY, 52(4), 520-533, APR 2017
  998. Complete response to short-term sorafenib treatment alone for hepatocellular carcinoma with bone, lymph node, and peritoneum metastases, HEPATOLOGY RESEARCH, 46(13), 1402-1408, DEC 2016
  999. Individual patient data meta-analysis of controlled attenuation parameter (CAP) technology for assessing steatosis, JOURNAL OF HEPATOLOGY, 66(5), 1022-1030, MAY 2017

Publications such as books

  1. 2006, Molecular pathologic application as a predictor of lymph node metastasis in submucosal colorectal carcinoma:implication of immunohistochemical alterations at the deepest invasive margin , 2006, 04, 171
  2. 2005, Role of invariant natural killer T cells in the regulation of the inflammatory response in experimental colitis in mice , 2005, 12, 35
  3. 1998, Methods in molecular medicine-hepatitis C protocols. Genotyping hepatitis C virus by type-specific primers for PCR based on NS5 region. , Humana Press, 1998
  4. 1998, Hepatitis C protocols; Genotyping hepatitis C virus by type-specific primers or PCR based on NS5 region , Humana Press, 1998
  5. 1994, Viral hepatitis and liver disease. High virus titer, slow virus decrease, genotype(]G0002[), and sequence variability of E2/NS1 HVR predict poor response to interferon therapy in chronic hepatitis C. , Springer Verlag, 1994
  6. 1994, High virus titer, slow virus decrease, genotypeII, and sequence variability of E2/NS1 HVR predict poor response to interferon therapy in chronic hepatitis C Viral hepatitis and liver disease , Springer Verlag, 1994
  7. Hepatotos C Virus Treatment, Highly Effective Therapy with Direct Acting Antivirals and Associated Viral Resistance, Springer, 2017

Invited Lecture, Oral Presentation, Poster Presentation

  1. DAA/PR therapy in Asian HCV patients, 2015/12/04, With Invitation
  2. Hepatitis B mouse model involving CTL, 2015/04/23, Without Invitation
  3. Ombitasvir/Paritaprevir/Ritonavir for treatment of HCV genotype 1b in Japanese patients with or without Cirrhosis: results from GIFT-1, 2015/05/22, Without Invitation
  4. All Oral Direct Acting Antiviral Therapy for Chronic Hepatitis C, 2015/10/17, With Invitation
  5. Circulating Tumor DNA Analysis for HCC., 2015/10/26, With Invitation
  6. All-oral Dual Combination of Daclatasvir plus Asunaprevir Compared with Telaprevir plus Peginterferon Alfa/Ribavirin in Treatment-maive Japanese Patients ChronicallyInfected with HCV Genotype 1b:Results from a Phase 3 Study, chayama kazuaki, 2014/11/11, Without Invitation
  7. Optimizing triple therapy, and IFN/RBV free regimens, chayama kazuaki, 2014/03/12, Without Invitation

Awards

  1. 2008年01月, GlaxoSmithKline Award

Patented

  1. Patent, JP5152745, 2012/12/14
  2. Patent, 特開平08-056672
  3. Patent, 特開平05-337000
  4. Patent, 5656159, 2014/12/05
  5. Patent, 5696317, 2015/02/20