Kazuaki Chayama

Last Updated :2020/07/01

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medicine), Professor
Web Site
E-mail
chayamahiroshima-u.ac.jp
Self-introduction
Since I became a Professor of the Faculty of Medicine, Hiroshima University, in September, 2000 and the head Professor of the Division of Gastroenterology of Hiroshima University Hospital in April 2002, our laboratory has evolved steadily as the result of the hard work of its doctors, staff and graduate students in the field of medical examination, education and research. We really appreciate the support of persons concerned with these activities.

Basic Information

Major Professional Backgrounds

  • 1981/05/01, Medical corporation Dojinkai, Clinical Fellow
  • 1986/04/01, National Public Officers Mutual Aid Association Federation, Clinical Fellow
  • 1996/07/01, same, Medical director
  • 2000/09/01, 2002/03/31, Hiroshima University, Faculty of Medicine, Professor
  • 2002/04/01, 2019/03/31, Hiroshima University, Graduate School of Biomedical Sciences , Professor
  • 2005/04/01, 2011/03/31, Hiroshima University, Hospital, Deputy Director
  • 2009/04/01, 2011/03/31, Hiroshima University, Vice Executive
  • 2011/04/01, 2015/03/31, Hiroshima University, Hospital, Director
  • 2012/04/01, 2015/03/31, Hiroshima University, Executive and Vice President
  • 2015/04/01, 2016/03/31, Hiroshima University, Special Assistant to the President

Educational Backgrounds

  • Hiroshima University, Faculty of Medicine, Japan, 1974/04, 1981/03

Academic Degrees

  • Doctor of Philosophy in Medical Sciences, The University of Tokyo

Educational Activity

  • 【Bachelor Degree Program】School of Medicine : Program of Medicine
  • 【Doctoral Program】Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Medicine

In Charge of Primary Major Programs

  • Dentistry
  • Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Gastroenterology

Research Keywords

  • nucleotide sequence|Hepatitis-B
  • epigenetics
  • liver cirrhosis
  • driver mutation
  • deep sequence
  • whole genome analysisi
  • Hepatitis-C
  • whole genome sequencing
  • hepatitis
  • hepatocellular carcinoma

Affiliated Academic Societies

Educational Activity

Course in Charge

  1. 2020, Undergraduate Education, Year, Clinical diagnosis and treatment I
  2. 2020, Undergraduate Education, Intensive, Practice for medical research
  3. 2020, Graduate Education (Doctoral Program) , First Semester, Advanced seminar on Gastroenterology and Metabolism
  4. 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced seminar on Gastroenterology and Metabolism
  5. 2020, Graduate Education (Doctoral Program) , First Semester, Advanced research on Gastroenterology and Metabolism
  6. 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced research on Gastroenterology and Metabolism
  7. 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Gastroenterology and Metabolism
  8. 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Gastroenterology and Metabolism
  9. 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Gastroenterology and Metabolism
  10. 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Gastroenterology and Metabolism

Research Activities

Academic Papers

  1. Regression of Idiopathic Thrombocytopenic Purpura in a Patient With Eradication of Hepatitis C Virus by Direct-Acting Antivirals, HEPATOLOGY, 71(1), 389-391, 202001
  2. Clinical Usefulness of Dual Red Imaging in Gastric Endoscopic Submucosal Dissection: A Pilot Study, CLINICAL ENDOSCOPY, 53(1), 54-59, 202001
  3. A Cost-Effectiveness Analysis of Glecaprevir/Pibrentasvir Versus Existing Direct-Acting Antivirals to Treat Chronic Hepatitis C in Japan, ADVANCES IN THERAPY, 37(1), 457-476, 202001
  4. Management of refractory ascites attenuates muscle mass reduction and improves survival in patients with decompensated cirrhosis, JOURNAL OF GASTROENTEROLOGY, 55(2), 217-226, 202002
  5. Preoperative PET-CT is useful for predicting recurrent extrahepatic metastasis of hepatocellular carcinoma after resection, EUROPEAN JOURNAL OF RADIOLOGY, 124, 202003
  6. Diagnostic Criteria of Flow-Mediated Vasodilation for Normal Endothelial Function and Nitroglycerin-Induced Vasodilation for Normal Vascular Smooth Muscle Function of the Brachial Artery, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 9(2), 20200121
  7. Clinical outcomes of endoscopic resection for superficial non-ampullary duodenal tumors, ENDOSCOPY INTERNATIONAL OPEN, 8(3), E354-E359, 202003
  8. Clinical usefulness of the S-O clip during colorectal endoscopic submucosal dissection in difficult-to-access submucosal layer, ENDOSCOPY INTERNATIONAL OPEN, 8(3), E437-E444, 202003
  9. Successful retreatment with 12 weeks of glecaprevir and pibrentasvir for a genotype 2a HCV-infected hemodialysis patient who failed to respond to 8 weeks of prior glecaprevir and pibrentasvir therapy, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(2), 267-270, 202004
  10. The Evaluation of Esophageal Motility Using Infusion Manometry with a Trans-nasal Endoscope: A Preliminary Study, INTERNAL MEDICINE, 59(7), 887-890, 2020
  11. Three Children Treated with Direct-acting Antivirals for Chronic Hepatitis C Virus Genotype 1b Infection, INTERNAL MEDICINE, 59(7), 941-944, 2020
  12. Serum amyloid A is a better predictive biomarker of mucosal healing than C-reactive protein in ulcerative colitis in clinical remission, BMC GASTROENTEROLOGY, 20(1), 20200403
  13. Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations, EBIOMEDICINE, 53, 202003
  14. Genomic Characterization of Non-Invasive Differentiated-Type Gastric Cancer in the Japanese Population, CANCERS, 12(2), 202002
  15. Sinusoidal obstruction syndrome post-treatment with trastuzumab emtansine (T-DM1) in advanced breast cancer, INTERNATIONAL CANCER CONFERENCE JOURNAL, 9(1), 18-23, 202001
  16. Comparative study on the replication of HCV1b genome between wild-type and cell culture-adaptive mutant in regard to sensitivities against anti-HCV drugs, MICROBIOLOGY AND IMMUNOLOGY, 64(4), 296-303, 202004
  17. Range of Normal Liver Stiffness and Factors Associated With Increased Stiffness Measurements in Apparently Healthy Individuals, CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 17(1), 54-+, 201901
  18. Dual Red Imaging Maintains Clear Visibility During Colorectal Endoscopic Submucosal Dissection, DIGESTIVE DISEASES AND SCIENCES, 64(1), 224-231, 201901
  19. Efficacy and safety of sofosbuvir-velpatasvir with or without ribavirin in HCV-infected Japanese patients with decompensated cirrhosis: an open-label phase 3 trial, JOURNAL OF GASTROENTEROLOGY, 54(1), 87-95, 201901
  20. Gastric Cancer with Submucosal Invasion after Successful Helicobacter pylori Eradication: A Propensity Score-Matched Analysis of Patients with Annual Patient Endoscopic Survey, DIGESTION, 99(1), 59-65, 2019
  21. The utility of a novel colonoscope with retroflexion for colorectal endoscopic submucosal dissection, ENDOSCOPY INTERNATIONAL OPEN, 7(2), E130-E137, 201902
  22. The impact of interferon-free direct-acting antivirals on clinical outcome after curative treatment for hepatitis C virus-associated hepatocellular carcinoma: Comparison with interferon-based therapy, JOURNAL OF MEDICAL VIROLOGY, 91(4), 650-658, 201904
  23. Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor, PLOS ONE, 14(2), 20190219
  24. Early-stage serrated adenocarcinomas are divided into several molecularly distinct subtypes, PLOS ONE, 14(2), 20190220
  25. Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures, JOURNAL OF GASTROENTEROLOGY, 54(3), 291-296, 201903
  26. Levocarnitine Use Is Associated With Improvement in Sarcopenia in Patients With Liver Cirrhosis, HEPATOLOGY COMMUNICATIONS, 3(3), 348-355, 201903
  27. Rectal Lymphoid Follicle Aphthous Lesions Frequently Progress to Ulcerative Colitis with Proximal Extension, INTERNAL MEDICINE, 58(5), 625-631, 201903
  28. Ser96Ala genetic variant of the human histidine-rich calcium-binding protein is a genetic predictor of recurrence after catheter ablation in patients with paroxysmal atrial fibrillation, PLOS ONE, 14(3), 20190306
  29. Epidemiological survey of hemoglobin A1c and liver fibrosis in a general population with non-alcoholic fatty liver disease, HEPATOLOGY RESEARCH, 49(3), 296-303, 201903
  30. Construction of a risk model for the development of metachronous squamous cell carcinoma after endoscopic resection of esopahageal squamous cell carcinoma, ESOPHAGUS, 16(2), 141-146, 201904
  31. A nationwide survey on non-B, non-C hepatocellular carcinoma in Japan: 2011-2015 update, JOURNAL OF GASTROENTEROLOGY, 54(4), 367-376, 201904
  32. Long-term prognosis after treatment for T1 carcinoma of laterally spreading tumors: a multicenter retrospective study, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 34(3), 481-490, 201903
  33. Early Multiphasic HBV Infection Initiation Kinetics Is Not Clone-Specific and Is Not Affected by Hepatitis D Virus (HDV) Infection, VIRUSES-BASEL, 11(3), 20190315
  34. Coffee with a high content of chlorogenic acids and low content of hydroxyhydroquinone improves postprandial endothelial dysfunction in patients with borderline and stage 1 hypertension, EUROPEAN JOURNAL OF NUTRITION, 58(3), 989-996, 201904
  35. Target of Triglycerides as Residual Risk for Cardiovascular Events in Patients With Coronary Artery Disease - Post Hoc Analysis of the FMD-J Study A, CIRCULATION JOURNAL, 83(5), 1064-+, 201905
  36. The Clinical Usefulness of the PillCam Progress Indicator for Route Selection in Double Balloon Endoscopy, INTERNAL MEDICINE, 58(10), 1375-1381, 2019
  37. HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response, GASTROENTEROLOGY, 156(8), 2313-+, 201906
  38. Experience with Balloon Dilatation in Crohn's and Non-Crohn's Benign Small-Bowel Strictures: Is There a Difference?, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2019
  39. Impact of sclerosing dacryoadenitis/sialadenitis on relapse during steroid therapy in patients with type 1 autoimmune pancreatitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 54(2), 259-264, 20190201
  40. Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes, CANCER CELL, 35(6), 932-+, 20190610
  41. Regulation of the Hepatitis B virus replication and gene expression by the multi-functional protein TARDBP, SCIENTIFIC REPORTS, 9, 20190611
  42. Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis, JOURNAL OF BIOMEDICAL SCIENCE, 26, 20190606
  43. Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice, JOURNAL OF GASTROENTEROLOGY, 54(7), 650-659, 201907
  44. Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study, JOURNAL OF HYPERTENSION, 37(5), 1083-1095, 201905
  45. Effect of Saxagliptin on Endothelial Function in Patients with Type 2 Diabetes: A Prospective Multicenter Study, SCIENTIFIC REPORTS, 9, 20190715
  46. Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice, JOURNAL OF GENERAL VIROLOGY, 100(7), 1123-1131, 201907
  47. Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of Hepatitis C Virus-Infected Cells and Liver to Identify Pathways Associated With Disease Development, GASTROENTEROLOGY, 157(2), 537-+, 201908
  48. Real-world virological efficacy and safety of daclatasvir/asunaprevir/beclabuvir in patients with chronic hepatitis C virus genotype 1 infection in Japan, JOURNAL OF GASTROENTEROLOGY, 54(8), 742-751, 201908
  49. y Integrated analysis of 8-week glecaprevir/pibrentasvir in Japanese and overseas patients without cirrhosis and with hepatitis C virus genotype 1 or 2 infection, JOURNAL OF GASTROENTEROLOGY, 54(8), 752-761, 201908
  50. Can surveillance colonoscopy be discontinued in an elderly population with diminutive polyps?, JOURNAL OF THE ANUS RECTUM AND COLON, 3(3), 128-135, 201907
  51. Helicobacter suis infection is associated with nodular gastritis-like appearance of gastric mucosa-associated lymphoid tissue lymphoma, CANCER MEDICINE, 8(9), 4370-4379, 201908
  52. Relationship between home blood pressure and vascular function in patients receiving antihypertensive drug treatment, HYPERTENSION RESEARCH, 42(8), 1175-1185, 201908
  53. Percutaneous transvenous shunt occlusion for portosystemic encephalopathy due to lenvatinib administration to a patient with hepatocellular carcinoma and portosystemic shunt, CLINICAL JOURNAL OF GASTROENTEROLOGY, 12(4), 341-346, 201908
  54. Correlation between Early Tumor Marker Response and Imaging Response in Patients with Advanced Hepatocellular Carcinoma Treated with Lenvatinib, ONCOLOGY, 97(2), 75-81, 2019
  55. Management of HCV patients in cases of direct-acting antiviral failure, EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 13(9), 839-848, 20190902
  56. Early changes in ammonia levels and liver function in patients with advanced hepatocellular carcinoma treated by lenvatinib therapy, SCIENTIFIC REPORTS, 9, 20190820
  57. Alcohol Use Disorders Identification Test-consumption Predicts the Risk of Excessive Alcohol Consumption After Liver Transplantation, TRANSPLANTATION PROCEEDINGS, 51(6), 1934-1938, 2019
  58. HOMA-IR: An independent predictor of advanced liver fibrosis in nondiabetic non-alcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 34(8), 1390-1395, 201908
  59. Preceding endoscopic submucosal dissection for T1 colorectal carcinoma does not affect the prognosis of patients who underwent additional surgery: a large multicenter propensity score-matched analysis, JOURNAL OF GASTROENTEROLOGY, 54(10), 897-906, 201910
  60. Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy, JOURNAL OF GASTROENTEROLOGY, 54(10), 907-915, 201910
  61. Clinical features of hepatocellular carcinoma in nonalcoholic fatty liver disease patients without advanced fibrosis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 34(9), 1626-1632, 201909
  62. Relationships Between Calcium Channel Blockers and Vascular Function Tests, AMERICAN JOURNAL OF HYPERTENSION, 32(7), 640-648, 201907
  63. Effects of the Dipeptidyl Peptidase 4 Inhibitor Alogliptin on Blood Pressure in Hypertensive Patients with Type 2 Diabetes Mellitus, AMERICAN JOURNAL OF HYPERTENSION, 32(7), 695-702, 201907
  64. Association of extremely high levels of high-density lipoprotein cholesterol with endothelial dysfunction in men, JOURNAL OF CLINICAL LIPIDOLOGY, 13(4), 664-672, 201908
  65. eVIDENCE: a practical variant filtering for low-frequency variants detection in cell-free DNA, SCIENTIFIC REPORTS, 9, 20191022
  66. Pruritus in patients with chronic liver disease and serum autotaxin levels in patients with primary biliary cholangitis, BMC GASTROENTEROLOGY, 19(1), 20191024
  67. Potential of Helicobacter pylori-uninfected signet ring cell carcinoma to invade the submucosal layer, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 34(11), 1955-1962, 201911
  68. Clinical Utility of Emergency Capsule Endoscopy for Diagnosing the Source and Nature of Ongoing Overt Obscure Gastrointestinal Bleeding, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2019, 20191201
  69. Investigation of Fluorodeoxyglucose Positron Emission Tomography for the Diagnosis of Solid Pseudopapillary Neoplasm of the Pancreas A Study Associated With a National Survey of Solid Pseudopapillary Neoplasms, PANCREAS, 48(10), 1312-1320, 2019
  70. A case of primary malignant melanoma of the esophagus with a widely expanded surface area, CLINICAL JOURNAL OF GASTROENTEROLOGY, 12(5), 424-428, 201910
  71. Advanced liver fibrosis effects on the response to sofosbuvir-based antiviral therapies for chronic hepatitis C, JOURNAL OF MEDICAL VIROLOGY, 90(12), 1834-1840, 201812
  72. CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic hepatitis B patients, JOURNAL OF VIRAL HEPATITIS, 25(12), 1555-1564, 201812
  73. The novel cutoff points for the FIB4 index categorized by age increase the diagnostic accuracy in NAFLD: a multi-center study, JOURNAL OF GASTROENTEROLOGY, 53(11), 1216-1224, 201811
  74. Early experience of seven hepatocellular carcinoma cases treated with regorafenib, CLINICAL CASE REPORTS, 6(11), 2217-2223, 201811
  75. Chromosome 4q25 Variant rs6817105 Bring Sinus Node Dysfunction and Left Atrial Enlargement, SCIENTIFIC REPORTS, 8, 20181001
  76. Comparison of clinical outcome of hepatic arterial infusion chemotherapy and sorafenib for advanced hepatocellular carcinoma according to macrovascular invasion and transcatheter arterial chemoembolization refractory status, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 33(10), 1780-1786, 201810
  77. Chromosomal Abnormalities in Human Lymphocytes after Computed Tomography Scan Procedure, RADIATION RESEARCH, 190(4), 424-432, 201810
  78. Molecular Mechanisms of Hepatocarcinogenesis Following Sustained Virological Response in Patients with Chronic Hepatitis C Virus Infection, VIRUSES-BASEL, 10(10), 201810
  79. IL-1 beta/ATF3-mediated induction of Ski2 expression enhances hepatitis B virus x mRNA degradation, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 503(3), 1854-1860, 20180910
  80. Maintenance of low inflammation level by the ZFHX3 SNP rs2106261 minor allele contributes to reduced atrial fibrillation recurrence after pulmonary vein isolation, PLOS ONE, 13(9), 20180904
  81. Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection, JOURNAL OF GASTROENTEROLOGY, 53(9), 1089-1097, 201809
  82. Clinical outcomes of sorafenib treatment failure for advanced hepatocellular carcinoma and candidates for regorafenib treatment in real-world practice, HEPATOLOGY RESEARCH, 48(10), 814-820, 201809
  83. New assessment of endothelial function measured by short time flow-mediated vasodilation: Comparison with conventional flow-mediated vasodilation measurement, INTERNATIONAL JOURNAL OF CARDIOLOGY, 265, 24-29, 20180815
  84. Watch-and-wait policy versus rituximab-combined chemotherapy in Japanese patients with intestinal follicular lymphoma, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 33(8), 1461-1468, 201808
  85. Long-term outcome of stereotactic body radiotherapy for patients with small hepatocellular carcinoma, HEPATOLOGY RESEARCH, 48(9), 701-707, 201808
  86. Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure, JOURNAL OF GENERAL VIROLOGY, 99(8), 1058-1065, 201808
  87. Hepatectomy versus stereotactic body radiotherapy for primary early hepatocellular carcinoma: A propensity-matched analysis in a single institution, SURGERY, 164(2), 219-226, 201808
  88. Acute hepatitis B virus infection in humanized chimeric mice has multiphasic viral kinetics, HEPATOLOGY, 68(2), 473-484, 201808
  89. Management of occult obscure gastrointestinal bleeding patients based on long-term outcomes, THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 11, 20180716
  90. A Data Mining-based Prognostic Algorithm for NAFLD-related Hepatoma Patients: A Nationwide Study by the Japan Study Group of NAFLD, SCIENTIFIC REPORTS, 8, 20180711
  91. Comparison of Stereotactic Body Radiation Therapy Combined With or Without Transcatheter Arterial Chemoembolization for Patients With Small Hepatocellular Carcinoma Ineligible for Resection or Ablation Therapies, TECHNOLOGY IN CANCER RESEARCH & TREATMENT, 17, 20180701
  92. Use of anticoagulants increases risk of bleeding after colorectal endoscopic submucosal dissection, ENDOSCOPY INTERNATIONAL OPEN, 6(7), E857-E864, 201807
  93. Sofosbuvir-velpatasvir plus ribavirin in Japanese patients with genotype 1 or 2 hepatitis C who failed direct-acting antivirals, HEPATOLOGY INTERNATIONAL, 12(4), 356-367, 201807
  94. HCN4 Gene Polymorphisms Are Associated With Occurrence of Tachycardia-Induced Cardiomyopathy in Patients With Atrial Fibrillation, CIRCULATION-GENOMIC AND PRECISION MEDICINE, 11(7), 201807
  95. Diagnosis of superficial esophageal squamous cell carcinoma invasion depth before endoscopic submucosal dissection, DISEASES OF THE ESOPHAGUS, 31(7), 201807
  96. Endothelial dysfunction, abnormal vascular structure and lower urinary tract symptoms in men and women, INTERNATIONAL JOURNAL OF CARDIOLOGY, 261, 196-203, 20180615
  97. Hepatic arterial infusion chemotherapy followed by sorafenib in patients with advanced hepatocellular carcinoma (HICS 55): an open label, non-comparative, phase II trial, BMC CANCER, 18, 20180604
  98. Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 500(2), 152-157, 20180602
  99. Reactive hyperemia-peripheral arterial tonometry is useful for assessment of not only endothelial function but also stenosis of the digital artery, INTERNATIONAL JOURNAL OF CARDIOLOGY, 260, 178-183, 20180601
  100. Preclinical Pharmacological Development of Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection, JOURNAL OF INFECTIOUS DISEASES, 217(11), 1761-1769, 20180601
  101. Curative Criteria After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinomas, DIGESTIVE DISEASES AND SCIENCES, 63(6), 1605-1612, 201806
  102. Cost-effectiveness analyses of anti-hepatitis C virus treatments using quality of life scoring among patients with chronic liver disease in Hiroshima prefecture, Japan, HEPATOLOGY RESEARCH, 48(7), 509-520, 201806
  103. Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts the development of hepatocellular carcinoma in patients with non-alcoholic fatty liver disease, HEPATOLOGY RESEARCH, 48(7), 521-528, 201806
  104. Silencing of Discoidin Domain Receptor-1 (DDR1) Concurrently Inhibits Multiple Steps of Metastasis Cascade in Gastric Cancer, TRANSLATIONAL ONCOLOGY, 11(3), 575-584, 201806
  105. Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction, PLOS ONE, 13(5), 20180521
  106. Short-term outcomes of endoscopic submucosal dissection for superficial cecal tumors: a comparison between extension and nonextension into the appendiceal orifice, THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 11, 20180501
  107. miR-135a-5p-mediated downregulation of protein tyrosine phosphatase receptor delta is a candidate driver of HCV-associated hepatocarcinogenesis, GUT, 67(5), 953-962, 201805
  108. Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations, JOURNAL OF HEPATOLOGY, 68(5), 959-969, 201805
  109. Long-term follow-up of clinical trial patients treated for chronic HCV infection with daclatasvir-based regimens, LIVER INTERNATIONAL, 38(5), 821-833, 201805
  110. In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors, GENOME RESEARCH, 28(5), 654-665, 201805
  111. Evaluation of glycemic variability in chronic liver disease patients with type 2 diabetes mellitus using continuous glucose monitoring, PLOS ONE, 13(4), 20180403
  112. Serial profiling of circulating tumor DNA for optimization of anti-VEGF chemotherapy in metastatic colorectal cancer patients, INTERNATIONAL JOURNAL OF CANCER, 142(7), 1418-1426, 20180401
  113. Clinical significance of small-bowel villous edema in patients with liver cirrhosis: A capsule endoscopy study, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 33(4), 825-830, 201804
  114. Efficacy and safety of ledipasvir/sofosbuvir with ribavirin in chronic hepatitis C patients who failed daclatasvir/asunaprevir therapy: pilot study, JOURNAL OF GASTROENTEROLOGY, 53(4), 548-556, 201804
  115. Efficacy and safety of glecaprevir/pibrentasvir in Japanese patients with chronic genotype 1 hepatitis C virus infection with and without cirrhosis, JOURNAL OF GASTROENTEROLOGY, 53(4), 557-565, 201804
  116. Efficacy and safety of glecaprevir/pibrentasvir in HCV-infected Japanese patients with prior DAA experience, severe renal impairment, or genotype 3 infection, JOURNAL OF GASTROENTEROLOGY, 53(4), 566-575, 201804
  117. Chronic kidney disease is associated with vascular smooth muscle dysfunction but not with endothelial dysfunction, INTERNATIONAL JOURNAL OF CARDIOLOGY, 254, 284-290, 20180301
  118. Clinical outcomes of endoscopic submucosal dissection for colorectal tumors: a large multicenter retrospective study from the Hiroshima GI Endoscopy Research Group, GASTROINTESTINAL ENDOSCOPY, 87(3), 714-722, 201803
  119. Risk factors for exacerbation of gastroesophageal varices and portosystemic encephalopathy during treatment with nucleos(t)ide analogs for hepatitis B virus-related cirrhosis, HEPATOLOGY RESEARCH, 48(4), 264-274, 201803
  120. Efficacy and safety of telaprevir with natural human interferon-beta and ribavirin in Japanese chronic hepatitis C patients with depression, HEPATOLOGY RESEARCH, 48(2), 184-192, 201802
  121. Clinical outcomes of stereotactic body radiotherapy for elderly patients with hepatocellular carcinoma, HEPATOLOGY RESEARCH, 48(2), 193-204, 201802
  122. Integrated Resistance Analysis of CERTAIN-1 and CERTAIN-2 Studies in Hepatitis C Virus-Infected Patients Receiving Glecaprevir and Pibrentasvir in Japan, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 62(2), 201802
  123. Combinational use of hepatitis B viral antigens predicts responses to nucleos(t)ide analogue/peg-interferon sequential therapy, JOURNAL OF GASTROENTEROLOGY, 53(2), 247-257, 201802
  124. Involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 53(2), 269-280, 201802
  125. Efficacy and safety of glecaprevir/pibrentasvir in Japanese patients with chronic genotype 2 hepatitis C virus infection, HEPATOLOGY, 67(2), 505-513, 201802
  126. Resistance characterization of hepatitis C virus genotype 2 from Japanese patients treated with ombitasvir and paritaprevir/ritonavir, JOURNAL OF MEDICAL VIROLOGY, 90(1), 109-119, 201801
  127. Daclatasvir and asunaprevir in hemodialysis patients with hepatitis C virus infection: a nationwide retrospective study in Japan, JOURNAL OF GASTROENTEROLOGY, 53(1), 119-128, 201801
  128. Characterization of Recombinant Flaviviridae Viruses Possessing a Small Reporter Tag, JOURNAL OF VIROLOGY, 92(2), 201801
  129. Brachial artery diameter as a marker for cardiovascular risk assessment: FMD-J study, ATHEROSCLEROSIS, 268, 92-98, 201801
  130. Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy, JOURNAL OF GASTROENTEROLOGY, 53(1), 107-118, 201801
  131. Efficacy and safety of edoxaban for treatment of portal vein thrombosis following danaparoid sodium in patients with liver cirrhosis, HEPATOLOGY RESEARCH, 48(1), 51-58, 201801
  132. Hepatocellular carcinoma treated with sorafenib: Arterial tumor perfusion in dynamic contrast-enhanced CT as early imaging biomarkers for survival, EUROPEAN JOURNAL OF RADIOLOGY, 98, 41-49, 201801
  133. Interrelationships Among Flow-Mediated Vasodilation, Nitroglycerine-Induced Vasodilation, Baseline Brachial Artery Diameter, Hyperemic Shear Stress, and Cardiovascular Risk Factors, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 7(1), 201801
  134. Comparison of Outcome of Hepatic Arterial Infusion Chemotherapy Combined with Radiotherapy and Sorafenib for Advanced Hepatocellular Carcinoma Patients with Major Portal Vein Tumor Thrombosis, ONCOLOGY, 94(4), 215-222, 2018
  135. Taking Warfarin with Heparin Replacement and Direct Oral Anticoagulant Is a Risk Factor for Bleeding after Endoscopic Submucosal Dissection for Early Gastric Cancer, DIGESTION, 97(3), 240-249, 2018
  136. Indication and Usefulness of Bile Juice Cytology for Diagnosis of Gallbladder Cancer, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2018
  137. Predictive Factors of Portal Hypertensive Enteropathy Exacerbation in Patients with Liver Cirrhosis: A Capsule Endoscopy Study, DIGESTION, 98(1), 33-40, 2018
  138. Clinical Significance of Reddish Depressed Lesions Observed in the Gastric Mucosa after Helicobacter pylori Eradication, DIGESTION, 98(1), 48-55, 2018
  139. Magnifying Endoscopy with Narrow Band Imaging in Estimating the Invasion Depth of Superficial Esophageal Squamous Cell Carcinomas, DIGESTION, 98(4), 249-256, 2018
  140. Endothelial Dysfunction, Increased Arterial Stiffness, and Cardiovascular Risk Prediction in Patients With Coronary Artery Disease: FMD-J (Flow-Mediated Dilation Japan) Study A, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 7(14), 20180717
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  300. Pulverized konjac glucomannan ameliorates oxazolone-induced colitis in mice, EUROPEAN JOURNAL OF NUTRITION, 54(6), 959-969, 201509
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  308. Role of 3-D conformal radiotherapy for major portal vein tumor thrombosis combined with hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma, HEPATOLOGY RESEARCH, 45(6), 607-617, 201506
  309. Detectability and clinical significance of serum hepatitis B virus ribonucleic acid, HEPATOBILIARY SURGERY AND NUTRITION, 4(3), 197-202, 201506
  310. Eicosapentaenoic acid/arachidonic acid ratio as a possible link between non-alcoholic fatty liver disease and cardiovascular disease, HEPATOLOGY RESEARCH, 45(5), 533-539, 201505
  311. Novel Robust in Vitro Hepatitis B Virus Infection Model Using Fresh Human Hepatocytes Isolated from Humanized Mice, AMERICAN JOURNAL OF PATHOLOGY, 185(5), 1275-1285, 201505
  312. Randomized Trial of Interferon- and Ribavirin-Free Ombitasvir/Paritaprevir/Ritonavir in Treatment-Experienced Hepatitis C Virus-Infected Patients, HEPATOLOGY, 61(5), 1523-1532, 201505
  313. Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection, SCIENCE TRANSLATIONAL MEDICINE, 7(282), 20150408
  314. Effect of Aldosterone-Producing Adenoma on Endothelial Function and Rho-Associated Kinase Activity in Patients With Primary Aldosteronism, HYPERTENSION, 65(4), 841-848, 201504
  315. Evaluation of early response to hepatic arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma using the combination of Response Evaluation Criteria in Solid Tumors and tumor markers, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(4), 726-732, 201504
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  317. Stereotactic body radiotherapy for patients with small hepatocellular carcinoma ineligible for resection or ablation therapies, HEPATOLOGY RESEARCH, 45(4), 378-386, 201504
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  320. Emerging treatments for chronic hepatitis C, JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 114(3), 204-215, 201503
  321. The effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(3), 619-627, 201503
  322. A Computer System To Be Used With Laser-based Endoscopy for Quantitative Diagnosis of Early Gastric Cancer, JOURNAL OF CLINICAL GASTROENTEROLOGY, 49(2), 108-115, 201502
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  325. mTOR and PDGF Pathway Blockade Inhibits Liver Metastasis of Colorectal Cancer by Modulating the Tumor Microenvironment, AMERICAN JOURNAL OF PATHOLOGY, 185(2), 399-408, 201502
  326. Ribavirin dose reduction during telaprevir/ribavirin/peg-interferon therapy overcomes the effect of the ITPA gene polymorphism, JOURNAL OF VIRAL HEPATITIS, 22(2), 166-174, 201502
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  328. Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity, Nature Communications, 6, 201501
  329. Major predictors of portal hypertensive enteropathy in patients with liver cirrhosis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(1), 124-130, 201501
  330. Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection, EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 9(1), 21-30, 201501
  331. Ratio of Serum Levels of AGEs to Soluble Form of RAGE Is a Predictor of Endothelial Function, DIABETES CARE, 38(1), 119-125, 201501
  332. Evaluation of Antibiotic Use to Prevent Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Cholangitis, HEPATO-GASTROENTEROLOGY, 62(138), 417-424, 2015
  333. Endoscopic Submucosal Dissection as Total Excisional Biopsy for Clinical T1 Colorectal Carcinoma, DIGESTION, 91(1), 64-69, 2015
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  335. Successful Use of Adalimumab for Treating Pyoderma Gangrenosum with Ulcerative Colitis under Corticosteroid-tapering Conditions, INTERNAL MEDICINE, 54(17), 2167-2172, 2015
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  338. Major predictors of portal hypertensive enteropathy in patients with liver cirrhosis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(1), 124-130, 2015
  339. A Computer System To Be Used With Laser-based Endoscopy for Quantitative Diagnosis of Early Gastric Cancer, JOURNAL OF CLINICAL GASTROENTEROLOGY, 49(2), 108-115, 2015
  340. Towards safer and appropriate application of endoscopic submucosal dissection for T1 colorectal carcinoma as total excisional biopsy: Future perspectives, DIGESTIVE ENDOSCOPY, 27(2), 216-222, 2015
  341. mTOR and PDGF Pathway Blockade Inhibits Liver Metastasis of Colorectal Cancer by Modulating the Tumor Microenvironment, AMERICAN JOURNAL OF PATHOLOGY, 185(2), 399-408, 2015
  342. Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection, EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 9(1), 21-30, 2015
  343. Effect of prolonged administration of pegylated interferon/ribavirin therapy in genotypes 2a and 2b: Propensity score-matched analysis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(2), 337-344, 2015
  344. Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity, Nature Communications, 6, 2015
  345. Endoscopic Submucosal Dissection as Total Excisional Biopsy for Clinical T1 Colorectal Carcinoma, DIGESTION, 91(1), 64-69, 2015
  346. Differences in serum microRNA profiles in hepatitis B and C virus infection, JOURNAL OF INFECTION, 70(3), 273-287, 2015
  347. The effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(3), 619-627, 2015
  348. Emerging treatments for chronic hepatitis C, JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 114(3), 204-215, 2015
  349. Rate of Unintended Helicobacter pylori Eradication in the Vietnamese, HELICOBACTER, 20(2), 156-157, 2015
  350. Evaluation of early response to hepatic arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma using the combination of Response Evaluation Criteria in Solid Tumors and tumor markers, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(4), 726-732, 2015
  351. Risk factors and management of positive horizontal margin in early gastric cancer resected by en bloc endoscopic submucosal dissection, GASTRIC CANCER, 18(2), 332-338, 2015
  352. Evaluation of Antibiotic Use to Prevent Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Cholangitis, HEPATO-GASTROENTEROLOGY, 62(138), 417-424, 2015
  353. Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection, SCIENCE TRANSLATIONAL MEDICINE, 7(282), 2015
  354. Stereotactic body radiotherapy for patients with small hepatocellular carcinoma ineligible for resection or ablation therapies, HEPATOLOGY RESEARCH, 45(4), 378-386, 2015
  355. Randomized Trial of Interferon- and Ribavirin-Free Ombitasvir/Paritaprevir/Ritonavir in Treatment-Experienced Hepatitis C Virus-Infected Patients, HEPATOLOGY, 61(5), 1523-1532, 2015
  356. Eicosapentaenoic acid/arachidonic acid ratio as a possible link between non-alcoholic fatty liver disease and cardiovascular disease, HEPATOLOGY RESEARCH, 45(5), 533-539, 2015
  357. Novel Robust in Vitro Hepatitis B Virus Infection Model Using Fresh Human Hepatocytes Isolated from Humanized Mice, AMERICAN JOURNAL OF PATHOLOGY, 185(5), 1275-1285, 2015
  358. Role of 3-D conformal radiotherapy for major portal vein tumor thrombosis combined with hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma, HEPATOLOGY RESEARCH, 45(6), 607-617, 2015
  359. Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis, HEPATOLOGY RESEARCH, 45(6), 656-662, 2015
  360. Disseminated carcinomatosis of the bone marrow originating from hepatocellular carcinoma. A case report, HEPATOLOGY RESEARCH, 45(6), 705-710, 2015
  361. The Time Course of Dynamic Computed Tomographic Appearance of Radiation Injury to the Cirrhotic Liver Following Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma, PLOS ONE, 10(6), 2015
  362. Rapid, Sensitive, and Accurate Evaluation of Drug Resistant Mutant (NS5A-Y93H) Strain Frequency in Genotype 1b HCV by Invader Assay, PLOS ONE, 10(6), 2015
  363. ADIPOQ polymorphisms are associated with insulin resistance in Japanese women, ENDOCRINE JOURNAL, 62(6), 513-521, 2015
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  369. Impact of alloimmune T cell responses on hepatitis C virus replication in liver transplant recipients, HUMAN IMMUNOLOGY, 75(12), 1259-1267, 201412
  370. Interferon lambda 4 polymorphism affects on outcome of telaprevir, pegylated interferon and ribavirin combination therapy for chronic hepatitis C, HEPATOLOGY RESEARCH, 44(14), E447-E454, 201412
  371. Non-invasive assessment of liver steatosis in non-alcoholic fatty liver disease, HEPATOLOGY RESEARCH, 44(14), E420-E427, 201412
  372. Predictive value of the IFNL4 polymorphism on outcome of telaprevir, peginterferon, and ribavirin therapy for older patients with genotype 1b chronic hepatitis C, JOURNAL OF GASTROENTEROLOGY, 49(12), 1548-1556, 201412
  373. Quantitative Effect of Natural Killer-Cell Licensing on Hepatocellular Carcinoma Recurrence after Curative Hepatectomy, CANCER IMMUNOLOGY RESEARCH, 2(12), 1142-1147, 201412
  374. Differences in K-ras and mitochondrial DNA mutations and microsatellite instability between colorectal cancers of Vietnamese and Japanese patients, BMC GASTROENTEROLOGY, 14, 20141130
  375. Endocannabinoid CB1 antagonists inhibit hepatitis C virus production, providing a novel class of antiviral host-targeting agents, JOURNAL OF GENERAL VIROLOGY, 95, 2468-2479, 201411
  376. Hepatitis C Virus Core Protein Suppresses Mitophagy by Interacting with Parkin in the Context of Mitochondrial Depolarization, AMERICAN JOURNAL OF PATHOLOGY, 184(11), 3026-3039, 201411
  377. Two patients treated with pegylated interferon/ribavirin/telaprevir triple therapy for recurrent hepatitis C after living donor liver transplantation, HEPATOLOGY RESEARCH, 44(12), 1259-1264, 201411
  378. Type 2 diabetes mellitus is associated with the fibrosis severity in patients with nonalcoholic fatty liver disease in a large retrospective cohort of Japanese patients, JOURNAL OF GASTROENTEROLOGY, 49(11), 1477-1484, 201411
  379. Upper limit of normal serum alanine aminotransferase levels in Japanese subjects, HEPATOLOGY RESEARCH, 44(12), 1196-1207, 201411
  380. Critical Role of Exogenous Nitric Oxide in ROCK Activity in Vascular Smooth Muscle Cells, PLOS ONE, 9(10), e109017, 20141003
  381. Case reports of portal vein thrombosis and bile duct stenosis after stereotactic body radiation therapy for hepatocellular carcinoma, HEPATOLOGY RESEARCH, 44(10), E273-E278, 201410
  382. New Insight Into the Enhanced Effect of Pegylated Interferon-alpha, HEPATOLOGY, 60(4), 1435-1437, 201410
  383. Efficacy of telaprevir-based therapy for difficult-to-treat patients with genotype 2 chronic hepatitis C in Japan, HEPATOLOGY RESEARCH, 45(7), 745-754, 20140901
  384. Antibiotic prophylaxis for endoscopic retrograde chlangiopancreatography increases the detection rate of drug-resistant bacteria in bile, JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 21(9), 712-718, 201409
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  386. Interleukin 28B polymorphism predicts interferon plus ribavirin treatment outcome in patients with hepatitis C virus-related liver cirrhosis: A multicenter retrospective study in Japan, HEPATOLOGY RESEARCH, 44(9), 983-992, 201409
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  390. Characteristic Epithelium with Low-Grade Atypia Appears on the Surface of Gastric Cancer after Successful Helicobacter pylori Eradication Therapy, HELICOBACTER, 19(4), 289-295, 201408
  391. Clinical outcomes of endoscopic submucosal dissection for superficial Barrett's adenocarcinoma, GASTROINTESTINAL ENDOSCOPY, 80(2), 239-245, 201408
  392. Detection of nonpolypoid colorectal neoplasia using magnifying endoscopy in colonic inflammatory bowel disease., Gastrointest Endosc Clin N Am., 24(3), 405-17, 20140701
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  395. Continued use of low-dose aspirin does not increase the risk of bleeding during or after endoscopic submucosal dissection for early gastric cancer, GASTRIC CANCER, 17(3), 489-496, 201407
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  398. Risk factors for delayed bleeding after endoscopic submucosal dissection for colorectal neoplasms, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 29(7), 877-882, 201407
  399. The association of insomnia with gastroesophageal reflux symptoms in biopsy-proven nonalcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 49(7), 1163-1174, 201407
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  401. Daclatasvir Plus Asunaprevir for Chronic HCV Genotype 1b Infection, HEPATOLOGY, 59(6), 2083-2091, 201406
  402. IFNL4/IL-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population, JOURNAL OF GENERAL VIROLOGY, 95, 1297-1306, 201406
  403. Timing of radiological improvement after steroid therapy in patients with autoimmune pancreatitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 49(6), 727-733, 201406
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  406. Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease, JOURNAL OF HUMAN GENETICS, 59(5), 241-246, 201405
  407. Characteristic Features of Cholangiocarcinoma Complicating Primary Sclerosing Cholangitis, HEPATO-GASTROENTEROLOGY, 61(131), 567-573, 201405
  408. IFNL4 polymorphism affects on outcome of telaprevir, peg-interferon and ribavirin combination therapy for chronic hepatitis C., Hepatol Res., 20140401
  409. On-treatment low serum HBV RNA level predicts initial virological response in chronic hepatitis B patients receiving nucleoside analogue therapy., Antivir Ther., 20140401
  410. Condition of muscularis mucosae is a risk factor for lymph node metastasis in T1 colorectal carcinoma, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 28(4), 1269-1276, 201404
  411. Efficacy of probucol for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label pilot study, HEPATOLOGY RESEARCH, 44(4), 429-435, 201404
  412. Endoscopic features and management of diminutive colorectal submucosal invasive carcinoma, DIGESTIVE ENDOSCOPY, 26, 78-83, 201404
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  414. Nonalcoholic Fatty Liver Disease and Cardiovascular Disease, CURRENT PHARMACEUTICAL DESIGN, 20(14), 2403-2411, 201404
  415. Poor Oral Health, That Is, Decreased Frequency of Tooth Brushing, Is Associated With Endothelial Dysfunction, CIRCULATION JOURNAL, 78(4), 950-954, 201404
  416. Rho-Associated Kinase Activity Is a Predictor of Cardiovascular Outcomes, HYPERTENSION, 63(4), 856-864, 201404
  417. Ultradeep Sequencing Study of Chronic Hepatitis C Virus Genotype 1 Infection in Patients Treated with Daclatasvir, Peginterferon, and Ribavirin, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 58(4), 2105-2112, 201404
  418. Long-Term Elimination of Hepatitis C Virus from Human Hepatocyte Chimeric Mice After Interferon-gamma Gene Transfer, HUMAN GENE THERAPY CLINICAL DEVELOPMENT, 25(1), 28-39, 20140301
  419. Efficacy and safety of sitagliptin for the treatment of nonalcoholic fatty liver disease with type 2 diabetes mellitus., Hepatogastroenterology., 61(130), 323-328, 20140301
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  421. Aryl hydrocarbon receptor plays protective roles in ConA-induced hepatic injury by both suppressing IFN- expression and inducing IL-22, INTERNATIONAL IMMUNOLOGY, 26(3), 129-137, 201403
  422. Is It Possible to Discriminate Between Neoplastic and Nonneoplastic Lesions in Ulcerative Colitis by Magnifying Colonoscopy?, INFLAMMATORY BOWEL DISEASES, 20(3), 508-513, 201403
  423. Is small-bowel capsule endoscopy effective for diagnosis of esophagogastric lesions related to portal hypertension?, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29(3), 511-516, 201403
  424. Non-invasive liver fibrosis score calculated by combination of virtual touch tissue quantification and serum liver functional tests in chronic hepatitis C patients, HEPATOLOGY RESEARCH, 44(3), 280-287, 201403
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  426. Predictors of incomplete resection and perforation associated with endoscopic submucosal dissection for colorectal tumors, GASTROINTESTINAL ENDOSCOPY, 79(3), 427-435, 201403
  427. Transarterial Therapy of Hepatocellular Carcinoma Fed by the Right Renal Capsular Artery, JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 25(3), 389-395, 201403
  428. Letter: Pitavastatin supplementation of PEG-IFN/ribavirin improves sustained virological response against HCV, Aliment Pharmacol Ther., 39(4), 443-4, 20140201
  429. Advanced Method for Evaluation of Gastric Cancer Risk By Serum Markers: Determination of True Low-Risk Subjects for Gastric Neoplasm, HELICOBACTER, 19(1), 1-8, 201402
  430. Clinical validity of the expanded criteria for endoscopic resection of undifferentiated-type early gastric cancer based on long-term outcomes, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 28(2), 639-647, 201402
  431. Serum asymmetric dimethylarginine levels are independently associated with procollagen III N-terminal peptide in nonalcoholic fatty liver disease patients, CLINICAL AND EXPERIMENTAL MEDICINE, 14(1), 45-51, 201402
  432. Serum interleukin-6 associated with hepatocellular carcinoma risk: a nested case-control study, Int J Cancer, 134(1), 154-163, 20140101
  433. Ultra deep sequencing study of HCV genotype 1 in chronic hepatitis patients treated with daclatasvir, peg-interferon and ribavirin, Antimicrob Agents Chemother, 20140101
  434. Efficacy and Safety of Sitagliptin for the Treatment of Nonalcoholic Fatty Liver Disease with Type 2 Diabetes Mellitus, HEPATO-GASTROENTEROLOGY, 61(130), 323-328, 2014
  435. Pilot Study of Stereotactic Body Radiation Therapy Combined with Transcatheter Arterial Chemoembolization for Small Hepatocellular Carcinoma, HEPATO-GASTROENTEROLOGY, 61(129), 31-36, 2014
  436. The effect of respiratory-gated positron emission tomography/computed tomography in patients with pancreatic cancer, HELLENIC JOURNAL OF NUCLEAR MEDICINE, 17(1), 31-36, 2014
  437. A randomized trial of daclatasvir with peginterferon alfa-2b and ribavirin for HCV genotype 1 infection, ANTIVIRAL THERAPY, 19(5), 491-499, 2014
  438. Characteristics of Metachronous Gastric Tumors after Endoscopic Submucosal Dissection for Gastric Intraepithelial Neoplasms, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2014
  439. Comparison of Small-Bowel Mucosal Injury between Low-Dose Aspirin and Non-Aspirin Non-Steroidal Anti-Inflammatory Drugs: A Capsule Endoscopy Study, DIGESTION, 89(3), 225-231, 2014
  440. Hepatitis C Virus (HCV) Reactivation Caused by Steroid Therapy for Dermatomyositis, INTERNAL MEDICINE, 53(23), 2689-2693, 2014
  441. Occupational Radiation Exposure during Endoscopic Retrograde Cholangiopancreatography and Usefulness of Radiation Protective Curtains, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2014
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  444. The IL28B SNP has a stronger regulatory effect on the expression of OAS1 than a nearby SNP located downstream of OAS1 in chronic HCV patients, HEPATOLOGY, 60, 1077A-1077A, 2014
  445. Pretreatment induction of ISGs in the presence of IFNL4 in hepatocytes but not in white blood cells is related with poor induction of ISGs following IFN-alpha therapy, HEPATOLOGY, 60, 1077A-1078A, 2014
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  447. Type 2 diabetes mellitus is associated with the fibrosis severity in patients with nonalcoholic fatty liver disease in a large retrospective cohort of Japanese patients, JOURNAL OF GASTROENTEROLOGY, 49(11), 1477-1484, 2014
  448. Usefulness of transabdominal ultrasonography for improved safety of capsule endoscopy in patients with crohn's disease, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29, 89-89, 2014
  449. Endocannabinoid CB1 antagonists inhibit hepatitis C virus production, providing a novel class of antiviral host-targeting agents, JOURNAL OF GENERAL VIROLOGY, 95, 2468-2479, 2014
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  451. Impact of alloimmune T cell responses on hepatitis C virus replication in liver transplant recipients, HUMAN IMMUNOLOGY, 75(12), 1259-1267, 2014
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  453. Quantitative Effect of Natural Killer-Cell Licensing on Hepatocellular Carcinoma Recurrence after Curative Hepatectomy, CANCER IMMUNOLOGY RESEARCH, 2(12), 1142-1147, 2014
  454. Non-invasive assessment of liver steatosis in non-alcoholic fatty liver disease, HEPATOLOGY RESEARCH, 44(14), E420-E427, 2014
  455. Interferon lambda 4 polymorphism affects on outcome of telaprevir, pegylated interferon and ribavirin combination therapy for chronic hepatitis C, HEPATOLOGY RESEARCH, 44(14), E447-E454, 2014
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  478. Noninvasive scoring systems in patients with nonalcoholic fatty liver disease with normal alanine aminotransferase levels, JOURNAL OF GASTROENTEROLOGY, 48(9), 1051-1060, 201309
  479. Risk factors for vertical incomplete resection in endoscopic submucosal dissection as total excisional biopsy for submucosal invasive colorectal carcinoma, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 28(9), 1247-1256, 201309
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  496. Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B, JOURNAL OF MEDICAL VIROLOGY, 85(5), 789-798, 201305
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  502. A Nonsynonymous Polymorphism in Semaphorin 3A as a Risk Factor for Human Unexplained Cardiac Arrest with Documented Ventricular Fibrillation, PLOS GENETICS, 9(4), 201304
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  508. Endoscopic assessment of colorectal cancer with superficial or deep submucosal invasion using magnifying colonoscopy., Clin Endosc., 46, 138-146, 20130301
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  511. Involvement of microRNA-224 in cell proliferation, migration, invasion, and anti-apoptosis in hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(3), 565-575, 201303
  512. Stereotactic body radiation therapy combined with transcatheter arterial chemoembolization for small hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(3), 530-536, 201303
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  514. Virological response and safety of 24-week telaprevir alone in Japanese patients infected with hepatitis C virus subtype 1b, JOURNAL OF VIRAL HEPATITIS, 20(3), 167-173, 201303
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  516. Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer, INTERNATIONAL JOURNAL OF CANCER, 132(4), 813-823, 20130215
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  519. Interleukin-28B polymorphisms and hepatitis C virus clearance, GENOME MEDICINE, 5, 20130129
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  521. Treatment of chronic hepatitis C virus infection in Japan: update on therapy and guidelines, JOURNAL OF GASTROENTEROLOGY, 48(1), 1-12, 201301
  522. Relationship between Narrow-Band Imaging Magnifying Observation and Pit Pattern Diagnosis in Colorectal Tumors, DIGESTION, 87(1), 53-58, 2013
  523. Replication Study of 15 Recently Published Loci for Body Fat Distribution in the Japanese Population, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 20(4), 336-350, 2013
  524. Clinical Characteristics of Patients who Developed Hepatocellular Carcinoma after Hepatitis C Virus Eradication with Interferon Therapy: Current Status in Japan, INTERNAL MEDICINE, 52(24), 2701-2706, 2013
  525. Hyperuricemia is independently associated with endothelial dysfunction in postmenopausal women but not in premenopausal women, BMJ OPEN, 3(11), 2013
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  527. Is Occult Obscure Gastrointestinal Bleeding a Definite Indication for Capsule Endoscopy? A Retrospective Analysis of Diagnostic Yield in Patients with Occult versus Overt Bleeding, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2013
  528. Chronic hepatitis B in patients coinfected with human immunodeficiency virus in Japan: a retrospective multicenter analysis, JOURNAL OF INFECTION AND CHEMOTHERAPY, 18(6), 883-890, 201212
  529. Clinical features of pharyngeal intraepithelial neoplasias and outcomes of treatment by endoscopic submucosal dissection, GASTROINTESTINAL ENDOSCOPY, 76(6), 1095-1103, 201212
  530. Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma according to Child-Pugh classification, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(12), 1850-1857, 201212
  531. Serum levels of pigment epithelium-derived factor (PEDF) are independently associated with procollagen III N-terminal peptide levels in patients with nonalcoholic fatty liver disease, CLINICAL BIOCHEMISTRY, 45(18), 1554-1557, 201212
  532. Bile Acid Promotes Intestinal Metaplasia and Gastric Carcinogenesis, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 21(11), 2101-2107, 201211
  533. Efficacy of rosuvastatin for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label, pilot study, HEPATOLOGY RESEARCH, 42(11), 1065-1072, 201211
  534. Increased insulinogenic index is an independent determinant of nonalcoholic fatty liver disease activity score in patients with normal glucose tolerance, DIGESTIVE AND LIVER DISEASE, 44(11), 935-939, 201211
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  539. Intima-Media Thickness of Brachial Artery, Vascular Function, and Cardiovascular Risk Factors, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(9), 2295-+, 201209
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  547. Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators, NATURE GENETICS, 44(7), 760-U182, 201207
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  555. Association of two polymorphisms of the IL28B gene with viral factors and treatment response in 1,518 patients infected with hepatitis C virus, JOURNAL OF GASTROENTEROLOGY, 47(5), 596-605, 201205
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  561. Value of Cytodiagnosis Using Endoscopic Nasopancreatic Drainage for Early Diagnosis of Pancreatic Cancer Establishing a New Method for the Early Detection of Pancreatic Carcinoma In Situ, PANCREAS, 41(4), 523-529, 201205
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  565. Long-Term Outcomes of Hepatic Arterial Port Implantation using a Coaxial Microcatheter System in 176 Patients with Hepatocellular Carcinoma., 61(1), 7-13, 20120301
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  568. Serum screening for detection of high-risk group for early-stage diffuse type gastric cancer in Japanese, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(3), 598-602, 201203
  569. Treatment of chronic hepatitis B with nucleos(t)ide analogues, HEPATOLOGY RESEARCH, 42(3), 219-225, 201203
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  575. Efficacy and safety of telaprevir, a new protease inhibitor, for difficult-to-treat patients with genotype 1 chronic hepatitis C, JOURNAL OF VIRAL HEPATITIS, 19(2), E134-E142, 201202
  576. Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor, NATURE MEDICINE, 18(2), 281-285, 201202
  577. Impact of Pegylated Interferon Therapy on Outcomes of Patients with Hepatitis C Virus-Related Hepatocellular Carcinoma After Curative Hepatic Resection, ANNALS OF SURGICAL ONCOLOGY, 19(2), 418-425, 201202
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  580. Toward the Establishment of a Prediction System for the Personalized Treatment of Chronic Hepatitis C, JOURNAL OF INFECTIOUS DISEASES, 205(2), 204-210, 20120115
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  582. Change in malpractice claims in Japanese gastroenterological practice, Am J Gastroenterol, 107(1), 143-144, 20120101
  583. Role of Natural Killer T Cells in the Mouse Colitis-Associated Colon Cancer Model, SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 75(1), 16-26, 201201
  584. Telaprevir with peginterferon and ribavirin for treatment-naive patients chronically infected with HCV of genotype 1 in Japan, JOURNAL OF HEPATOLOGY, 56(1), 78-84, 201201
  585. Clinical validity of endoscopic submucosal dissection for submucosal invasive gastric cancer: a single-center study, GASTRIC CANCER, 15(1), 97-105, 201201
  586. Computer-aided system for predicting the histology of colorectal tumors by using narrow-band imaging magnifying colonoscopy, GASTROINTESTINAL ENDOSCOPY, 75(1), 179-185, 201201
  587. Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women, JOURNAL OF HUMAN GENETICS, 57(1), 46-51, 201201
  588. Geranylgeranylacetone, Heat Shock Protein 90/AMP-Activated Protein Kinase/Endothelial Nitric Oxide Synthase/Nitric Oxide Pathway, and Endothelial Function in Humans, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(1), 153-U350, 201201
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  590. Amino Acid Substitution in HCV Core Region and Genetic Variation near the IL28B Gene Affect Viral Dynamics during Telaprevir, Peginterferon and Ribavirin Treatment, INTERVIROLOGY, 55(6), 417-425, 2012
  591. Amino Acid Substitution in HCV Core/NS5A Region and Genetic Variation Near IL28B Gene Affect Treatment Efficacy to Interferon plus Ribavirin Combination Therapy, INTERVIROLOGY, 55(3), 231-241, 2012
  592. Evaluation of Individual Risk in Nonvariceal Gastrointestinal Bleeding Patients with NSAID Administration: A Multicenter Study in Japan, DIGESTION, 86(3), 187-193, 2012
  593. Evaluation of the mRECIST and alpha-Fetoprotein Ratio for Stratification of the Prognosis of Advanced-Hepatocellular-Carcinoma Patients Treated with Sorafenib, ONCOLOGY, 83(4), 192-200, 2012
  594. Gastric Cancer Development after Helicobacter pylori Eradication Therapy: A New Form of Gastric Neoplasia, DIGESTION, 85(1), 61-67, 2012
  595. Identification of novel HCV deletion mutants in chronic hepatitis C patients, ANTIVIRAL THERAPY, 17(8), 1551-1561, 2012
  596. Flow-mediated vasodilation is augmented in a corkscrew collateral artery compared with that in a native artery in patients with thromboangiitis obliterans (Buerger disease), JOURNAL OF VASCULAR SURGERY, 54(6), 1689-1697, 201112
  597. Low Prevalence of Helicobacter pylori-negative Gastric Cancer among Japanese, HELICOBACTER, 16(6), 415-419, 201112
  598. Quantitative analysis of colorectal lesions observed on magnified endoscopy images, JOURNAL OF GASTROENTEROLOGY, 46(12), 1382-1390, 201112
  599. Assessment of Trypsinogen-2 Levels as an Early Diagnostic for Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis, PANCREAS, 40(8), 1206-1210, 201111
  600. Clinical outcome of esophageal varices after hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with major portal vein tumor thrombus, HEPATOLOGY RESEARCH, 41(11), 1046-1056, 201111
  601. Eradication of hepatitis C virus genotype 1 after liver transplantation by interferon therapy before surgery: Report of three patients with analysis of interleukin-28 polymorphism, hepatitis C virus core region and interferon-sensitivity determining regio, HEPATOLOGY RESEARCH, 41(11), 1126-1131, 201111
  602. Platelet count for predicting fibrosis in nonalcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 46(11), 1300-1306, 201111
  603. The Water-Soluble Extract from Cultured Medium of Ganoderma lucidum (Reishi) Mycelia (Designated as MAK) Ameliorates Murine Colitis Induced by Trinitrobenzene Sulphonic Acid, SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 74(5), 454-462, 201111
  604. A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population, HUMAN MOLECULAR GENETICS, 20(19), 3884-3892, 20111001
  605. Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area, JOURNAL OF HUMAN GENETICS, 56(10), 716-719, 201110
  606. Frequent somatic mutations of mitochondrial DNA in traditional serrated adenomas but not in sessile serrated adenomas of the colorectum, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 26(10), 1565-1569, 201110
  607. IL28B polymorphism may guide pegylated interferon plus ribavirin therapy even after curative treatment for hepatitis C virus-related hepatocellular carcinoma, JOURNAL OF VIRAL HEPATITIS, 18(10), E550-E560, 201110
  608. Lymphocyte subset characterization associated with persistent hepatitis C virus infection and subsequent progression of liver fibrosis, HUMAN IMMUNOLOGY, 72(10), 821-826, 201110
  609. Prevention of hepatitis B virus reactivation in immunosuppressive therapy or chemotherapy, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 15(5), 634-640, 201110
  610. Rho-Associated Kinase Activity, Endothelial Function, and Cardiovascular Risk Factors, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 31(10), 2353-2359, 201110
  611. RISK FACTORS FOR BLEEDING AFTER ENDOSCOPIC SUBMUCOSAL DISSECTION OF GASTRIC EPITHELIAL NEOPLASM, DIGESTIVE ENDOSCOPY, 23(4), 290-295, 201110
  612. Intestinal tuberculosis with hoarseness as a chief complaint due to mediastinal lymphadenitis, Case Rep Gastroenterol, 5(3), 540-545, 20110901
  613. Inverse Association of IL28B Genotype and Liver mRNA Expression of Genes Promoting or Suppressing Antiviral State, JOURNAL OF MEDICAL VIROLOGY, 83(9), 1597-1607, 201109
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  615. Statins induce apoptosis and inhibit proliferation in cholangiocarcinoma cells, INTERNATIONAL JOURNAL OF ONCOLOGY, 39(3), 561-568, 201109
  616. Helicobacter pylori cagA polymorphism and gastric inflammation: An international comparison between Japanese and Brazilian patients, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 46(9), 1051-1056, 201109
  617. Impact of Viral Amino Acid Substitutions and Host Interleukin-28B Polymorphism on Replication and Susceptibility to Interferon of Hepatitis C Virus, HEPATOLOGY, 54(3), 764-771, 201109
  618. Improved detectability of small-bowel lesions via capsule endoscopy with computed virtual chromoendoscopy: A pilot study, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 46(9), 1133-1137, 201109
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  620. In Vivo Adaptation of Hepatitis C Virus in Chimpanzees for Efficient Virus Production and Evasion of Apoptosis, HEPATOLOGY, 54(2), 425-433, 201108
  621. Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers, NATURE GENETICS, 43(8), 797-U108, 201108
  622. Effects of Hepatitis B Virus Infection on the Interferon Response in Immunodeficient Human Hepatocyte Chimeric Mice, JOURNAL OF INFECTIOUS DISEASES, 204(2), 224-228, 20110715
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  624. Treatment Strategy for Early Hepatocellular Carcinomas: Comparison of Radiofrequency Ablation With or Without Transcatheter Arterial Chemoembolization and Surgical Resection, JOURNAL OF SURGICAL ONCOLOGY, 104(1), 3-9, 20110701
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  627. ME3738 enhances the effect of interferon and inhibits hepatitis C virus replication both in vitro and in vivo, JOURNAL OF HEPATOLOGY, 55(1), 11-18, 201107
  628. Prevention of hepatitis B virus reactivation in immunosuppressive therapy or chemotherapy., Clin Exp Nephrol., 20110601
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  636. Will There Be an HCV Meeting in 2020? Summary of the 17th International Meeting on Hepatitis C Virus and Related Viruses., Gastroenterolog, 20110501
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  664. Current Status of Narrow-Band Imaging Magnifying Colonoscopy for Colorectal Neoplasia in Japan, DIGESTION, 83(3), 167-172, 2011
  665. Splenectomy in Chronic Hepatic Disorders: Portal Vein Thrombosis and Improvement of Liver Function, DIGESTIVE SURGERY, 28(1), 9-14, 2011
  666. Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease, BMC MEDICAL GENETICS, 11, 20101222
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  674. Evaluation of portosystemic collaterals by MDCT-MPR imaging for management of hemorrhagic esophageal varices, EUROPEAN JOURNAL OF RADIOLOGY, 76(2), 239-245, 201011
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  676. Quantitative analysis and development of a computer-aided system for identification of regular pit patterns of colorectal lesions, GASTROINTESTINAL ENDOSCOPY, 72(5), 1047-1051, 201011
  677. Transcatheter chemoembolization for unresectable hepatocellular carcinoma and comparison of five staging systems, HEPATOLOGY RESEARCH, 40(11), 1082-1091, 201011
  678. Elimination of Hepatitis C Virus by Short Term NS3-4A and NS5B Inhibitor Combination Therapy in Human Hepatocyte Chimeric Mice., J Hepatol., 20101001
  679. ITPA Polymorphism Affects Ribavirin-Induced Anemia and Outcomes of Therapy-A Genome-Wide Study of Japanese HCV Virus Patients, GASTROENTEROLOGY, 139(4), 1190-1197, 201010
  680. Potential role for vascular endothelial growth factor-D as an autocrine factor for human gastric carcinoma cells, CANCER SCIENCE, 101(10), 2121-2127, 201010
  681. Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations, NATURE GENETICS, 42(10), 893-896, 201010
  682. Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants, VIROLOGY, 405(2), 361-369, 20100930
  683. Efficacy of ecabet sodium enema on intractable rectal ulcer after piecemeal endoscopic mucosal resection for rectal tumor, Clin J Gastroenterol, 3(6), 285-288, 20100901
  684. Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations, Nat Genet, 42(10), 893-6, 20100901
  685. A multicenter, open-label, dose-ranging study to exploratively evaluate the efficacy, safety, and dose-response of tolvaptan in patients with decompensated liver cirrhosis, JOURNAL OF GASTROENTEROLOGY, 45(9), 979-987, 201009
  686. Characterization of colorectal tumors using narrow-band imaging magnification: combined diagnosis with both pit pattern and microvessel features, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 45(9), 1084-1092, 201009
  687. Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients, JOURNAL OF HEPATOLOGY, 53(3), 439-443, 201009
  688. Evaluation of long-term entecavir treatment in stable chronic hepatitis B patients switched from lamivudine therapy, HEPATOLOGY INTERNATIONAL, 4(3), 594-600, 201009
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  690. Is Structural Remodeling of Fibrillated Atria the Consequence of Tissue Hypoxia?, CIRCULATION JOURNAL, 74(9), 1815-1821, 201009
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  694. Hypersensitivity Reactions to Transcatheter Chemoembolization with Cisplatin and Lipiodol Suspension for Unresectable Hepatocellular Carcinoma, JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 21(8), 1219-1225, 201008
  695. Importance of Serum Concentration of Adefovir for Lamivudine-Adefovir Combination Therapy in Patients with Lamivudine-Resistant Chronic Hepatitis B, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 54(8), 3205-3211, 201008
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  697. Non-polypoid colorectal neoplasms in ulcerative colitis, Gastrointest Endosc, 20(3), 525-542, 20100701
  698. Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH, JOURNAL OF GASTROENTEROLOGY, 45(7), 750-757, 201007
  699. Establishment of functional telomerase immortalized human hepatocytes and a hepatic stellate cell line for telomere-targeting anticancer drug development, CANCER SCIENCE, 101(7), 1678-1685, 201007
  700. HBx protein is indispensable for development of viraemia in human hepatocyte chimeric mice, JOURNAL OF GENERAL VIROLOGY, 91, 1854-1864, 201007
  701. Practical evaluation of a mouse with chimeric human liver model for hepatitis C virus infection using an NS3-4A protease inhibitor, JOURNAL OF GENERAL VIROLOGY, 91, 1668-1677, 201007
  702. Intra-arterial 5-fluorouracil/interferon combination therapy for hepatocellular carcinoma with portal vein tumor thrombosis and extrahepatic metastases, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25(6), 1117-1122, 201006
  703. Long-term use of entecavir in nucleoside-naive Japanese patients with chronic hepatitis B infection, JOURNAL OF HEPATOLOGY, 52(6), 791-799, 201006
  704. Pioglitazone improves endothelium-dependent vasodilation in hypertensive patients with impaired glucose tolerance in part through a decrease in oxidative stress, ATHEROSCLEROSIS, 210(2), 521-524, 201006
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  706. A spontaneous Type 1 electrocardiogram pattern in lead V-2 is an independent predictor of ventricular fibrillation in Brugada syndrome, EUROPACE, 12(3), 410-416, 201003
  707. Percutaneous radiofrequency ablation as first-line treatment for small hepatocellular carcinoma: Results and prognostic factors on long-term follow up, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25(3), 597-604, 201003
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  710. Impaired myocardial blood flow reserve in subjects with metabolic syndrome analyzed using positron emission tomography and N-13 labeled ammonia, EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 37(2), 368-376, 201002
  711. A Water-soluble extract from culture medium of ganoderma lucidum mycelia suppresses the development of colorectal adenoma, Hiroshima J Med Sci, 59(1), 1--6, 20100101
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  713. Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis C virus infection for the fiscal year 2008 in Japan, HEPATOLOGY RESEARCH, 40(1), 8-13, 201001
  714. Regular surveillance by imaging for early detection and better prognosis of hepatocellular carcinoma in patients infected with hepatitis C virus, JOURNAL OF GASTROENTEROLOGY, 45(1), 105-112, 201001
  715. Sarpogrelate Hydrochloride, a Selective 5-hydroxytryptamine(2A) Antagonist, Augments Autologous Bone Marrow Mononuclear Cell Implantation-induced Improvement in Endothelium-dependent Vasodilation in Patients With Critical Limb Ischemia, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 55(1), 56-61, 201001
  716. Pilot Study of Systemic Combination Therapy with S-1, an Oral Fluoropyrimidine, and Cisplatin for Hepatocellular Carcinoma with Extrahepatic Metastases, HEPATO-GASTROENTEROLOGY, 57(102-03), 1272-1278, 2010
  717. Clinical Impact of Tumor Invasion Depth Staging of Esophageal Squamous Cell Carcinoma Using Endoscopic Ultrasonography, HEPATO-GASTROENTEROLOGY, 58(104), 1423-1429, 2010
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  720. Natural Course of Lugol-Voiding Lesions in Patients with Superficial Esophageal Squamous Cell Carcinoma, DIGESTION, 82(1), 60-65, 2010
  721. Relationship between Helicobacter pylori Tyrosine-Phosphorylated CagA-Related Markers and the Development of Diffuse-Type Gastric Cancers: A Case-Control Study, DIGESTION, 82(1), 10-17, 2010
  722. Synchronous and Subsequent Lesions of Serrated Adenomas and Tubular Adenomas of the Colorectum, PATHOBIOLOGY, 77(5), 273-277, 2010
  723. Infliximab treatment for Crohn's disease in a patient with IgA nephropathy, Clin J Gastroenterol, 2, 380-383, 20091201
  724. Absence of viral interference and different susceptibility to interferon between hepatitis B virus and hepatitis C virus in human hepatocyte chimeric mice, JOURNAL OF HEPATOLOGY, 51(6), 1046-1054, 200912
  725. Detection of Helicobacter hepaticus in Human Bile Samples of Patients with Biliary Disease, HELICOBACTER, 14(6), 545-551, 200912
  726. Effects of structural variations of APOBEC3A and APOBEC3B genes in chronic hepatitis B virus infection, HEPATOLOGY RESEARCH, 39(12), 1159-1168, 200912
  727. Adoptive immunotherapy with liver allograft-derived lymphocytes induces anti-HCV activity after liver transplantation in humans and humanized mice, JOURNAL OF CLINICAL INVESTIGATION, 119(11), 3226-3235, 200911
  728. Ecabet sodium induces neuronal nitric oxide synthase-derived nitric oxide synthesis and gastric adaptive relaxation in the human stomach, JOURNAL OF GASTROENTEROLOGY, 44(11), 1118-1124, 200911
  729. Cheilitis granulomatosa as an early manifestation of Crohn's disease, Clin J Gastroenterol, 2, 190-193, 20091001
  730. Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease, ATHEROSCLEROSIS, 206(2), 604-610, 200910
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  733. Amphipathic DNA Polymers Inhibit Hepatitis C Virus Infection by Blocking Viral Entry, GASTROENTEROLOGY, 137(2), 673-681, 200908
  734. Meta-analysis used to identify factors associated with the effectiveness of proton pump inhibitors against non-erosive reflux disease, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24(8), 1326-1332, 200908
  735. Successful hepatitis B vaccination in liver transplant recipients with donor-specific hyporesponsiveness, TRANSPLANT INTERNATIONAL, 22(8), 805-813, 200908
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  737. KNACK AND PRACTICAL TECHNIQUE OF COLONOSCOPIC TREATMENT FOCUSED ON ENDOSCOPIC MUCOSAL RESECTION USING SNARE, DIGESTIVE ENDOSCOPY, 21, S38-S42, 200907
  738. Predicting the clinical response to cytapheresis in steroid-refractory or -dependent ulcerative colitis using contrast-enhanced ultrasonography, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 44(7), 831-837, 200907
  739. THERAPEUTIC STRATEGY FOR COLORECTAL LATERALLY SPREADING TUMOR, DIGESTIVE ENDOSCOPY, 21, S43-S46, 200907
  740. Transarterial Infusion Chemotherapy Using Cisplatin-Lipiodol Suspension With or Without Embolization for Unresectable Hepatocellular Carcinoma, CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 32(4), 687-694, 200907
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  742. Deletion of angiotensin II type I receptor reduces hepatic steatosis, JOURNAL OF HEPATOLOGY, 50(6), 1226-1235, 200906
  743. Nifedipine Interferes with Migration of Vascular Smooth Muscle Cells via Inhibition of Pyk2-Src Axis, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 16(3), 230-238, 200906
  744. Predicting the response to 48-week combination therapy with peginterferon alpha-2b plus ribavirin from the estimated HCV RNA load index after negative serum change in genotype 1b hepatitis C patients, HEPATOLOGY RESEARCH, 39(6), 531-538, 200906
  745. G-to-A Hypermutation in Hepatitis B Virus (HBV) and Clinical Course of Patients with Chronic HBV Infection, JOURNAL OF INFECTIOUS DISEASES, 199(11), 1599-1607, 200906
  746. Predicting the clinical response to cytapheresis in steroid-refractory or -dependent ulcerative colitis using contrast-enhanced ultrasonography, Scand J Gastroenterol, 44(5), 405-411, 20090501
  747. A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians, NATURE GENETICS, 41(5), 591-595, 200905
  748. A Polymorphism in MAPKAPK3 Affects Response to Interferon Therapy for Chronic Hepatitis C, GASTROENTEROLOGY, 136(5), 1796-1805, 200905
  749. Clinical prevention of gastric cancer by Helicobacter pylori eradication therapy: a systematic review, JOURNAL OF GASTROENTEROLOGY, 44(5), 365-371, 200905
  750. Evaluation and validation of computed virtual chromoendoscopy in early gastric cancer, GASTROINTESTINAL ENDOSCOPY, 69(6), 1052-1058, 200905
  751. Intra-arterial 5-fluorouracil/interferon combination therapy for advanced hepatocellular carcinoma with or without three-dimensional conformal radiotherapy for portal vein tumor thrombosis, JOURNAL OF GASTROENTEROLOGY, 44(5), 492-502, 200905
  752. Pathogenetic role of the tyrosine-phosphorylated CagA EPIYA sequence of Helicobacter pylori in histological gastritis in Japanese patients, JOURNAL OF GASTROENTEROLOGY, 44(5), 405-411, 200905
  753. Cigarette Smoking Abolishes Ischemic Preconditioning-Induced Augmentation of Endothelium-Dependent Vasodilation, HYPERTENSION, 53(4), 674-U151, 200904
  754. Comparison of detectability of small-bowel lesions between capsule endoscopy and double-balloon endoscopy for patients with suspected small-bowel disease, GASTROINTESTINAL ENDOSCOPY, 69(4), 857-865, 200904
  755. Effectiveness of prokinetic agents against diseases external to the gastrointestinal tract, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24(4), 537-546, 200904
  756. Metachronous multiple esophageal squamous cell carcinomas and Lugol-voiding lesions after endoscopic mucosal resection, ENDOSCOPY, 41(4), 304-309, 200904
  757. Randomized Trial of High-Dose Interferon-alpha-2b Combined With Ribavirin in Patients With Chronic Hepatitis C: Correlation Between Amino Acid Substitutions in the Core/NS5A Region and Virological Response to Interferon Therapy, JOURNAL OF MEDICAL VIROLOGY, 81(4), 640-649, 200904
  758. Successful treatment of pulmonary metastases associated with advanced hepatocellular carcinoma by systemic 5-fluorouracil combined with interferon-alpha in a hemodialysis patient, HEPATOLOGY RESEARCH, 39(4), 415-420, 200904
  759. Usefulness of Endoscopic Ultrasonography in Determining the Depth of Invasion and Indication for Endoscopic Treatment of Early Gastric Cancer, JOURNAL OF CLINICAL GASTROENTEROLOGY, 43(4), 318-322, 200904
  760. Dose comparison study of pegylated interferon-alpha-2b plus ribavirin in naive Japanese patients with hepatitis C virus genotype 2: A randomized clinical trial, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24(3), 366-371, 200903
  761. Narrow-band imaging magnification predicts the histology and invasion depth of colorectal tumors, GASTROINTESTINAL ENDOSCOPY, 69(3), 631-636, 200903
  762. The first Japanese case of COACH syndrome, HEPATOLOGY RESEARCH, 39(3), 318-323, 200903
  763. FDG positron emission tomography/computed tomography for the detection of extrahepatic metastases from hepatocellular carcinoma, HEPATOLOGY RESEARCH, 39(2), 134-142, 200902
  764. Significant Correlation Between Spleen Volume and Thrombocytopenia in Liver Transplant Patients: A Concept for Predicting Persistent Thrombocytopenia, LIVER TRANSPLANTATION, 15(2), 208-215, 200902
  765. Involvement of Epithelial Cell Transforming Sequence-2 Oncoantigen in Lung and Esophageal Cancer Progression, CLINICAL CANCER RESEARCH, 15(1), 256-266, 20090101
  766. Trend in Japanese malpractice litigation involving gastrointestinal endoscopy, Am J Gastroenterol, 104(1), 251-252, 20090101
  767. Evaluation of Patients with Esophageal Varices After Endoscopic Injection Sclerotherapy Using Multiplanar Reconstruction MDCT Images, AMERICAN JOURNAL OF ROENTGENOLOGY, 192(1), 122-130, 200901
  768. Little Necessity of Acid Inhibition against Proton Pump Inhibitor Rebound Effects and Prior Helicobacter pylori Eradication Therapy in Gastric Ulcer Patients: A Randomized Prospective Study, HEPATO-GASTROENTEROLOGY, 56(91-92), 624-628, 2009
  769. Usefulness and limitations of transabdominal ultrasonography for detecting small-bowel tumors, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 44(3), 332-338, 2009
  770. Rapid progression of Epstein -Barr-virus-positive gastric diffuse large B-cell lymphoma during chemoradiotherapy: a case report, Clin J Gastroenterol, 1, 105-109, 20081218
  771. Beneficial effects of living-donor liver transplantation on esophageal varices, JOURNAL OF GASTROENTEROLOGY, 43(12), 982-989, 200812
  772. Efficacy of atorvastatin for the treatment of nonalcoholic steatohepatitis with dyslipidemia, METABOLISM-CLINICAL AND EXPERIMENTAL, 57(12), 1711-1718, 200812
  773. Expression of multidrug resistance-associated protein 2 is involved in chemotherapy resistance in human pancreatic cancer, INTERNATIONAL JOURNAL OF ONCOLOGY, 33(6), 1187-1194, 200812
  774. Vascular Endothelial Growth Factor C Stimulates Progression of Human Gastric Cancer via Both Autocrine and Paracrine Mechanisms, CLINICAL CANCER RESEARCH, 14(22), 7205-7214, 20081115
  775. Aging and Hypertension Are Independent Risk Factors for Reduced Number of Circulating Endothelial Progenitor Cells, AMERICAN JOURNAL OF HYPERTENSION, 21(11), 1203-1209, 200811
  776. Colorectal endoscopic submucosal dissection: present status and future perspective, including its differentiation from endoscopic mucosal resection, JOURNAL OF GASTROENTEROLOGY, 43(9), 641-651, 200809
  777. Establishment of an infectious genotype 1b hepatitis C virus clone in human hepatocyte chimeric mice, JOURNAL OF GENERAL VIROLOGY, 89, 2108-2113, 200809
  778. Strategy of endoscopic treatment for colorectal tumor: recent progress and perspective, 353-366, 20080815
  779. Etiology and outcome of acute liver failure: Retrospective analysis of 50 patients treated at a single center, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23(8), 1216-1222, 200808
  780. Endoscopic ultrasonography with double baloon enteroscopy for small bowel diseases, Techniques in Gastrointestinal Endoscopy, 10(3), 113-118, 20080724
  781. Clinicopathological features of elderly patients with hepatitis C virus-related hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY, 43(7), 550-557, 200807
  782. Coronary vasospasm produces reversible perfusion defects observed during adenosine triphosphate stress myocardial single-photon emission computed tomography, CLINICAL CARDIOLOGY, 31(7), 310-316, 200807
  783. Cytoprotective effect of tauroursodeoxycholate on hepatocyte apoptosis induced by peroxisome proliferator-activated receptor gamma ligand, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23(7), E198-E206, 200807
  784. Evaluation of gastric cancer risk using topography of histological gastritis: A large-scaled cross-sectional study, DIGESTIVE DISEASES AND SCIENCES, 53(7), 1818-1823, 200807
  785. Relationship between Augmentation Index and Flow-Mediated Vasodilation in the Brachial Artery, HYPERTENSION RESEARCH, 31(7), 1293-1298, 200807
  786. A Case of Fulminant Hepatic Failure Caused by Hepatitis E virus79117, Clinical Journal of gastroenterology, 1, 69-74, 20080603
  787. Role of the angiotensin II type 2 receptor in arterial remodeling after wire injury in mice, HYPERTENSION RESEARCH, 31(6), 1241-1249, 200806
  788. Strategy for treatment of nonerosive reflux disease in Asia, WORLD JOURNAL OF GASTROENTEROLOGY, 14(20), 3123-3128, 20080528
  789. Angiotensin II-Induced osteopontin expression in vascular smooth muscle cells involves G(q/11), Ras, ERK, Src and Ets-1, HYPERTENSION RESEARCH, 31(5), 987-998, 200805
  790. Genetic polymorphisms and head and neck cancer risk (Review), INTERNATIONAL JOURNAL OF ONCOLOGY, 32(5), 945-973, 200805
  791. Systemic gemcitabine combined with intra-arterial low-dose cisplatin and 5-fluorouracil for advanced hepatocellular carcinoma: Seven cases, WORLD JOURNAL OF GASTROENTEROLOGY, 14(16), 2602-2608, 20080428
  792. Ablation of the Bach1 gene leads to the suppression of atherosclerosis in Bach1 and apolipoprotein E double knockout mice, HYPERTENSION RESEARCH, 31(4), 783-792, 200804
  793. Prospective study of short-term peginterferon-alpha-2a monotherapy in patients who had a virological response at 2 weeks after initiation of interferon therapy, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23(4), 541-545, 200804
  794. Risk factors for hepatocellular carcinoma in a Japanese population: A nested case-control study, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 17(4), 846-854, 200804
  795. Long-term ultrasonographic follow-up study of gastric motility in patients with functional dyspepsia, JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 42(2), 144-149, 200803
  796. Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients, HYPERTENSION, 51(2), 446-453, 20080201
  797. Susceptibility of chimeric mice with livers repopulated by serially subcultured human hepatocytes to hepatitis B virus, HEPATOLOGY, 47(2), 435-446, 200802
  798. The number of criminal prosecutions against physicians due to medical negligence is on the rise in Japan, Am J Emerg Med, 26(1), 105-106, 20080117
  799. Clinical significance of type V-I pit pattern subclassification in determining the depth of invasion of colorectal neoplasms, WORLD JOURNAL OF GASTROENTEROLOGY, 14(2), 211-217, 20080114
  800. Presence of Poorly Differentiated Component Correlated with Submucosal Invasion in the Early Diffuse-type Gastric Cancer, HEPATO-GASTROENTEROLOGY, 55(88), 2264-2268, 2008
  801. Optical biopsy of early gastroesophageal cancer by catheter-based reflectance-type laser-scanning confocal microscopy, JOURNAL OF BIOMEDICAL OPTICS, 13(5), 2008
  802. Prophylaxis against Recurrence of HBV Hepatitis after Living-donor Liver Transplantation, HEPATO-GASTROENTEROLOGY, 55(86-87), 1746-1749, 2008
  803. Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells, JOURNAL OF GASTROENTEROLOGY, 43(4), 298-304, 2008
  804. Combination therapy of oral fluoropyrimidine anticancer drug S-1 and interferon alpha for HCC patients with extrahepatic metastases, ONCOLOGY, 75(1-2), 8-16, 2008
  805. Evaluation of colon cancer vascularity by flash echo imaging, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 43(2), 223-228, 2008
  806. Predictors and long-term prognostic implications of angiographic slow/no-flow during percutaneous coronary intervention for acute myocardial infarction, INTERNAL MEDICINE, 47(10), 899-906, 2008
  807. Relation between histologic gastritis and gastric motility in Japanese patients with functional dyspepsia: evaluation by transabdominal ultrasonography, JOURNAL OF GASTROENTEROLOGY, 43(5), 332-337, 2008
  808. Role of the Gastrin-Gastrin Receptor System in the Expansive Growth of Human Gastric Neoplasms, DIGESTION, 78(2-3), 163-170, 2008
  809. Validating a Markov Model of Treatment for Hepatitis C Virus-related Hepatocellular Carcinoma, METHODS OF INFORMATION IN MEDICINE, 47(6), 529-540, 2008
  810. Selective decrease in colonic CD56(+) T and CD161(+) T cells in the inflamed mucosa of patients with ulcerative colitis, WORLD JOURNAL OF GASTROENTEROLOGY, 13(45), 5995-6002, 20071207
  811. Primary follicular lymphoma of the gastrointestinal tract: a retrospective case series, Endoscopy, 20071201
  812. Single lymphocyte analysis with a microwell array chip, CYTOMETRY PART A, 71A(12), 1003-1010, 200712
  813. Successful treatment of an entecavir-resistant hepatitis B virus variant, JOURNAL OF MEDICAL VIROLOGY, 79(12), 1811-1817, 200712
  814. Images in cardiovascular medicine. Corkscrew collaterals in thromboangitis obliterans (Buerger's disease)., CIRCULATION, E539-E540, 20071120
  815. Biliary complications after duct-to-duct biliary reconstruction in living-donor liver transplantation: Causes and treatment, WORLD JOURNAL OF SURGERY, 31(11), 2222-2229, 200711
  816. Evaluation of microvessels in colorectal tumors by narrow band imaging magnification, GASTROINTESTINAL ENDOSCOPY, 66(5), 945-952, 200711
  817. Similar effects of recombinant interferon-alpha-2b and natural interferon-alpha when combined with intra-arterial 5-fluorouracil for the treatment of advanced hepatocellular carcinoma, LIVER INTERNATIONAL, 27(9), 1209-1216, 200711
  818. Effects of a 24-week course of interferon-a therapy after curative treatment of hepatitis C virus-associated hepatocellular carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(40), 5343-5350, 20071028
  819. Low-dose intermittent interferon-alpha therapy for HCV-related liver cirrhosis after curative treatment of hepatocellular carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(39), 5188-5195, 20071021
  820. Genetic polymorphisms and esophageal cancer risk, INTERNATIONAL JOURNAL OF CANCER, 121(8), 1643-1658, 20071015
  821. Nodular gastritis with Helicobacter pylori infection is strongly associated with diffuse-type gastric cancer in young patients, DIGESTIVE ENDOSCOPY, 19(4), 180-184, 200710
  822. Pretreatment predictor of response, time to progression, and survival to intraarterial 5-fluorouracil/interferon combination therapy in patients with advanced hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY, 42(10), 845-853, 200710
  823. Treatment of functional dyspepsia with serotonin agonists: A meta-analysis of randomized controlled trials, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(10), 1566-1570, 200710
  824. Pycnogenol, French maritime pine bark extract, augments endothelium-dependent vasodilation in humans., HYPERTENSION RESEARCH, 775-780, 20070901
  825. Pycnogenol (R), French maritime pine bark extract, augments endothelium-dependent vasodilation in humans, HYPERTENSION RESEARCH, 30(9), 775-780, 200709
  826. Serum pepsinogen levels in the Japanese population: Prospective study of 9 years of follow-up, HEPATO-GASTROENTEROLOGY, 54(78), 1887-1890, 200709
  827. Involvement of Kruppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(29), 3932-3938, 20070807
  828. Acute moderate-intensity exercise induces vasodilation through oxide bioavailiability an increase in nitric in humans, AMERICAN JOURNAL OF HYPERTENSION, 20(8), 825-830, 200708
  829. Low serum level of hepatitis B indicates unlikely reactivation core-related antigen of hepatitis after cessation of lamivudine therapy, HEPATOLOGY RESEARCH, 37(8), 661-666, 200708
  830. The long-term outcome of patients with bleeding gastric varices after balloon-occluded retrograde transvenous obliteration, JOURNAL OF GASTROENTEROLOGY, 42(8), 663-672, 200708
  831. Immunohistochemical molecular markers as predictors of curability of endoscopically resected submucosal colorectal cancer, WORLD JOURNAL OF GASTROENTEROLOGY, 13(28), 3829-3835, 20070728
  832. Elevated levels of serum advanced glycation end products in patients with non-alcoholic steatohepatitis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(7), 1112-1119, 200707
  833. Endoscopic submucosal dissection for colorectal neoplasia: possibility of standardization, GASTROINTESTINAL ENDOSCOPY, 66(1), 100-107, 200707
  834. Optical biopsy of GI lesions by reflectance-type laser-scanning confocal microscopy, GASTROINTESTINAL ENDOSCOPY, 66(1), 144-149, 200707
  835. Techniques and pitfalls of endoscopic submucosal dissection for colorectal tumors, DIGESTIVE ENDOSCOPY, 19, S30-S33, 200707
  836. Clinical significance of mucosal suppressors of cytokine signaling 3 expression in ulcerative colitis, WORLD JOURNAL OF GASTROENTEROLOGY, 13(21), 2939-2944, 20070607
  837. Predicting the need for surgery in Crohn's disease with contrast harmonic ultrasound, Scand J Gastroenterol, 42, 577-585, 20070601
  838. Should splenectomy be performed for hepatitis C patients undergoing living-donor liver transplantation, J Gastroenterol Hepatol, 22(6), 959-960, 20070601
  839. Magnifying endoscopy with narrow band imaging for diagnosis of colorectal tumors, GASTROINTESTINAL ENDOSCOPY, 65(7), 988-995, 200706
  840. Repetition of ischemic preconditioning augments endothelium-dependent vasodilation in humans - Role of endothelium-derived nitric oxide and endothelial progenitor cells, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 27(6), 1403-1410, 200706
  841. Earthworm fibrinolytic enzyme: anti-tumor activity on human hepatoma cells in vitro and in vivo, CHINESE MEDICAL JOURNAL, 120(10), 898-904, 20070520
  842. Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon, FEBS LETTERS, 581(10), 1983-1987, 20070515
  843. Measurement of flow-mediated vasodilation of the brachial artery - A comparison of measurements in the seated and supine positions, CIRCULATION JOURNAL, 71(5), 736-740, 200705
  844. Role of Helicobacter pylori infection and chronic inflammation in gastric cancer in the cardia, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 37(5), 365-369, 200705
  845. Serum HBV RNA is a predictor of early emergence of the YMDD mutant in patients treated with lamivudine, HEPATOLOGY, 45(5), 1179-1186, 200705
  846. Helicobacter pylori-associated gastritisis related to babA2expression without heterogeneity of the 3' region of the cagA genotype in Gastric Biopsy Specimens, Pathobiology, 74(5), 1-7, 20070401
  847. Reduced expression of heme oxygenase-1 in patients with coronary atherosclerosis, HYPERTENSION RESEARCH, 30(4), 341-348, 200704
  848. Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 49(4), 221-227, 200704
  849. Host factors contributing to the discovery of gastric cancer after successful eradication therapy of Helicobacter pylori: Preliminary report, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(4), 571-576, 200704
  850. New method of evaluating gastric mucosal blood flow by ultrasound, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 42(4), 513-518, 200704
  851. Usefulness of EUS with double-balloon enteroscopy for diagnosis of small-bowel diseases, GASTROINTESTINAL ENDOSCOPY, 65(3), 412-420, 200703
  852. Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(3), 304-310, 200703
  853. The effects of different intensities of acute exercise on systemic hemodynamics and forearm vascular function in humans., AMERICAN JUORNAL OF HYPERTENSION, 825-830, 20070214
  854. Roles of Rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 49(6), 698-705, 20070213
  855. Carvedilol improves endothelium-dependent vasodilation in patients with dilated cardiomyopathy., HEART, 247-248, 20070201
  856. Cavernous hemangioma in the ascending colon treated by endoscopic mucosal resection, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(2), 280-281, 200702
  857. Dual effect of APOBEC3G on Hepatitis B virus, JOURNAL OF GENERAL VIROLOGY, 88, 432-440, 200702
  858. Immune response to CagA protein is associated with improved platelet count after Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura, HELICOBACTER, 12(1), 36-42, 200702
  859. Clinical features and prognosis of patients with extrahepatic metastases from hepatocellular carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(3), 414-420, 20070121
  860. Basis of decreased risk of gastric cancer in severe atrophic gastritis with eradication of Helicobacter pylori, DIGESTIVE DISEASES AND SCIENCES, 52(1), 232-239, 200701
  861. Gene delivery of paraoxonase-1 inhibits neointimal hyperplasia after arterial balloon-injury in rabbits fed a high-fat diet, HYPERTENSION RESEARCH, 30(1), 85-91, 200701
  862. Lymphatic vessel density at the site of deepest penetration as a predictor of lymph node metastasis in submucosal colorectal cancer, DISEASES OF THE COLON & RECTUM, 50(1), 13-21, 200701
  863. Non-SCN5A related Brugada syndromes: Verification of normal splicing and trafficking of SCN5A without exonic mutations, ANNALS OF HUMAN GENETICS, 71, 8-17, 200701
  864. Balloon-occluded retrograde transvenous obliteration for portal-systemic encephalopathy due to superior mesenteric-caval shunt via the right gonadal vein, INTERNAL MEDICINE, 46(17), 1479-1480, 2007
  865. Efficacy of percutaneous cementoplasty for bone metastasis from hepatocellular carcinoma, ONCOLOGY, 72(5-6), 285-292, 2007
  866. Eicosapentaenoic acid could permit maintenance of the original ribavirin dose in chronic hepatitis C virus patients during the first 12 weeks of combination therapy with pegylated interferon-alpha and ribavirin, INTERVIROLOGY, 50(6), 439-446, 2007
  867. Helicobacter pylori - Associated gastritis is related to babA2 expression without heterogeneity of the 3 ' region of the cagA genotype in gastric biopsy specimens, PATHOBIOLOGY, 74(5), 309-316, 2007
  868. Predicting the need for surgery in Crohn's disease with contrast harmonic ultrasound, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 42(5), 577-585, 2007
  869. Defensive medicine practices among gastroenterologists in Japan, WORLD JOURNAL OF GASTROENTEROLOGY, 12(47), 7671-7675, 20061221
  870. Effects of acute administration of caffeine on vascular function, AMERICAN JOURNAL OF CARDIOLOGY, 98(11), 1538-1541, 20061201
  871. Advantage of endoscopic submucosal dissection compared with EMR for early gastric cancer, GASTROINTESTINAL ENDOSCOPY, 64(6), 877-883, 200612
  872. Feasibility of freeze-dried sera for serological and molecular biological detection of hepatitis B and C viruses, JOURNAL OF CLINICAL MICROBIOLOGY, 44(12), 4593-4595, 200612
  873. Genetic and pathologic characteristics of gastrointestinal stromal tumors in extragastric lesions, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 18(6), 1067-1071, 200612
  874. Small-intestinal Peutz-Jeghers polyps resected by endoscopic polypectomy with double-balloon enteroscopy and removal confirmed by ultrasonography, DIGESTIVE DISEASES AND SCIENCES, 51(12), 2337-2340, 200612
  875. Medical malpractice litigation related to gastrointestinal endoscopy in Japan: A two-decade review of civil court cases, WORLD JOURNAL OF GASTROENTEROLOGY, 12(42), 6857-6860, 20061114
  876. Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 50(11), 3867-3874, 200611
  877. High-magnification colonoscopy (with Videos), Gastrointest Endosc, 64(4), 604-613, 20061001
  878. Management of Intraductal Papillary -mucinous Neoplasm of the Pancreas, J Clin Gastroenterol, 40(9), 856-862, 20061001
  879. Autologous bone marrow mononuclear cell implantation induces angiogenesis and bone regeneration in a patient with compartment syndrome, CIRCULATION JOURNAL, 70(10), 1362-1364, 200610
  880. Endoscopic submucosal dissection for residual/local recurrence of early gastric cancer after endoscopic mucosal resection, ENDOSCOPY, 38(10), 996-1000, 200610
  881. Genetic progression and divergence in superficial esophageal squamous cell carcinoma by loss of heterozygosity analysis, ONCOLOGY REPORTS, 16(4), 685-691, 200610
  882. High-magnification colonoscopy (with videos), GASTROINTESTINAL ENDOSCOPY, 64(4), 604-613, 200610
  883. Management of intraductal papillary-mucinous neoplasm of the pancreas - Treatment strategy based on morphologic classification, JOURNAL OF CLINICAL GASTROENTEROLOGY, 40(9), 856-862, 200610
  884. Suppression of interferon-related promoter activation by hepatitis C virus proteins expressed in cultured cells., Hiroshima Journal of Medical Sciences, 55(3), 71-77, 20060901
  885. A case of Crohn's disease with hydronephrosis caused by ureteropelvic junction obstruction, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 18(9), 1015-1018, 200609
  886. A ligand for peroxisome proliferator-activated receptor gamma inhibits human cholangiocarcinoma cell growth: Potential molecular targeting strategy for cholangioma, DIGESTIVE DISEASES AND SCIENCES, 51(9), 1650-1657, 200609
  887. Helicobacter pylori infection is the major risk factor for gastric inflammation in the cardia, DIGESTIVE DISEASES AND SCIENCES, 51(9), 1582-1588, 200609
  888. Medical malpractice litigation in gastroenterological practice in Japan: A 22-yr review of civil court cases, AMERICAN JOURNAL OF GASTROENTEROLOGY, 101(9), 1951-1953, 200609
  889. Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 346(3), 658-664, 20060804
  890. Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 346(1), 67-73, 20060721
  891. Pit pattern diagnosis for colorectal neoplasia using narrow band imaging magnification, Dig Endosc, 18, S52-S56, 20060701
  892. A case of multiple hepatic peribiliary cysts which contributed to the obstructive jaundice and led to liver failure at the young man with von Recklinghausen's disease, HEPATOLOGY RESEARCH, 35(3), 222-227, 200607
  893. Clinicopathologic and genetic characteristics of gastric cancer in young male and female patients, ONCOLOGY REPORTS, 16(1), 11-15, 200607
  894. Double-balloon enteroscopy in patients with GI bleeding of obscure origin, GASTROINTESTINAL ENDOSCOPY, 64(1), 135-140, 200607
  895. Gastrointestinal stromal tumor in jejunum: Diagnosis using contrast-enhanced ultrasonography and double-balloon enteroscopy, DIGESTIVE DISEASES AND SCIENCES, 51(7), 1236-1240, 200607
  896. Neuropilin-1 is involved in regulation of apoptosis and migration of human colon cancer, INTERNATIONAL JOURNAL OF ONCOLOGY, 29(1), 105-116, 200607
  897. Real-time visualization and quantitation of canine gastric mucosal blood flow by contrast-enhanced ultrasonography, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 41(7), 856-861, 200607
  898. Delection of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach., Int J Oncology, 28, 1361-1367, 20060601
  899. Deletion of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach, INTERNATIONAL JOURNAL OF ONCOLOGY, 28(6), 1361-1367, 200606
  900. Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production, ATHEROSCLEROSIS, 186(2), 390-395, 200606
  901. Surface structure of antral gastric mucosa represents the status of histologic gastritis: Fundamental evidence for the evaluation of antral gastritis by magnifying endoscopy, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 21(5), 837-841, 200605
  902. The usefulness of transabdominal ultrasound for the diagnosis of lower gastrointestinal bleeding, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 23(8), 1267-1272, 20060415
  903. Ablation of indiopathic ventricular tachycardia with a left Bundle-Branch block morphology originating from the pulmonary artery., J Arrthmia, 22(3), 180-186, 20060401
  904. Coronary sinus Morphology in Patients with Posteroseptal Atrioventricular Accessory Pathways., J Arrthmia, 22(3), 149-154, 20060401
  905. Edaravone(3-Methyl-1-Phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases., Recent Patents on Cardiovascular Drug Discovery, 1, 85-93, 20060401
  906. Oxidative stress, endothelial function and angiogenesis induced by cell therapy and gene therapy, CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 7(2), 109-116, 200604
  907. The effect of Helicobacter pylori eradication therapy on gastric ulcer healing after endoscopic mucosal resection, JOURNAL OF CLINICAL GASTROENTEROLOGY, 40(4), 293-296, 200604
  908. The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines, INTERNATIONAL JOURNAL OF ONCOLOGY, 28(4), 915-921, 200604
  909. Helicobacter pylori infection is the major risk factor for atrophic gastritis, San Diego, 20060301
  910. Aged garlic extract has potential suppressive effect on colorectal adenomas in humans, JOURNAL OF NUTRITION, 136(3), 821S-826S, 200603
  911. Measurement of hepatitis B virus core-related antigen is valuable for identifying patients who are at low risk of lamivudine resistance, LIVER INTERNATIONAL, 26(1), 90-96, 200602
  912. Nonpolypoid (flat and depressed) colorectal neoplasms, GASTROENTEROLOGY, 130(2), 566-576, 200602
  913. Suppression of STAT3 activity by duplin, which is a negative regulator of the Wnt signal, JOURNAL OF BIOCHEMISTRY, 139(2), 305-314, 200602
  914. Causal role of Helicobacter pylori infection and eradication therapy in gastric carcinogenesis., World J Gastroenterol, 12(1), 10-16, 20060101
  915. Evaluation of endoscopic and histological findings in Helicobacter pylori-positive Japanese young adults, J Gastroenterol Hepatol, 21, 258-261, 20060101
  916. dEvaluation of endoscopic and histological findings in Helicobacter pylori-positive Japanese young adults, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 21(1), 258-261, 200601
  917. Development of a novel method to detect Helicobacter pylori cagA genotype from paraffin-embedded materials: Comparison between patients with duodenal ulcer and gastric cancer in young Japanese, DIGESTION, 73(1), 47-53, 2006
  918. Evolution of hepatitis C virus quasispecies during ribavirin and interferon-alpha-2b combination therapy and interferon-alpha-2b monotherapy, INTERVIROLOGY, 49(6), 352-361, 2006
  919. Nuclear and mitochondrial DNA microsatellite instability in gastrointestinal stromal tumors, PATHOBIOLOGY, 73(2), 93-97, 2006
  920. Prolonged negative HCV-RNA status led to a good outcome in chronic hepatitis C patients with genotype 1b and super-high viral load, INTERVIROLOGY, 49(6), 362-369, 2006
  921. Successive, rapid recurrences of in-stent restenoses in a woman with angina pectoris, INTERNAL MEDICINE, 45(19), 1093-1096, 2006
  922. Glycochenodeoxycholate plays a carcinogenic role in immortalized mouse cholanglocytes via oxidative DNA damage, FREE RADICAL BIOLOGY AND MEDICINE, 39(11), 1418-1427, 20051201
  923. Biphasic effect of HMG-CoA reductase inhibitor, pitavastatin, on vascular endothelial cells and angiogenesis, CIRCULATION JOURNAL, 69(12), 1547-1555, 200512
  924. Smoking, endothelial function, and Rho-kinase in humans, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 25(12), 2630-2635, 200512
  925. Monocyte chemoattractant protein-1 transfection induces angiogenesis and tumorigenesis of gastric carcinoma in nude mice via macrophage recruitment, CLINICAL CANCER RESEARCH, 11(21), 7629-7636, 20051101
  926. Role of the JNK pathway in thrombin-induced ICAM-1 expression in endothelial cells, CARDIOVASCULAR RESEARCH, 68(2), 289-298, 20051101
  927. Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus, HEPATOLOGY, 42(5), 1046-1054, 200511
  928. Reliable and cost-effective screening of inherited heterozygosity by Zn2+-cyclen polyacrylamide gel electrophoresis, CLINICAL CHEMISTRY, 51(11), 2195-2198, 200511
  929. Somatic mutations of mitochondrial DNA in digestive tract cancers, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(11), 1679-1684, 200511
  930. A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5 ' flanking region of SMYD3 is a risk factor for human cancers, NATURE GENETICS, 37(10), 1104-1107, 200510
  931. Adrenomedullin causes coronary vasodilation in humans - Effects of inhibition of nitric oxide synthesis, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 46(4), 534-539, 200510
  932. Diagnostic ability of high-frequency ultrasound probe sonography in staging early gastric cancer, especially for submucosal invasion, ABDOMINAL IMAGING, 30(5), 518-523, 200510
  933. Relationship between endothelial function in the coronary and brachial arteries, CLINICAL CARDIOLOGY, 28(10), 460-466, 200510
  934. Therapeutic effect of repeated natural killer T cell stimulation in mouse cholangitis complicated by colitis, DIGESTIVE DISEASES AND SCIENCES, 50(10), 1844-1851, 200510
  935. Expression of p53 protein in esophageal squamous cell carcinoma: relation to hypoxia-inducible factor-1alpha, angiogenesis and apoptosis., Pathobiology, 72, 179-185, 20050901
  936. Cardiac glands hyperplastic polyp of the stomach, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(9), 1461-1463, 200509
  937. A nuclear receptor-mediated choleretic action of fibrates is associated with enhanced canalicular membrane fluidity and transporter activity mediating bile acid-independent bile secretion, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 12(4), 211-217, 20050825
  938. Expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in early gastric carcinoma: correlation with clinicopathological parameters, CANCER LETTERS, 226(1), 85-90, 20050808
  939. A combination of the Helicobacter pylori stool antigen test and urea breath test is useful for clinical evaluation of eradication therapy: A multicenter study, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(8), 1241-1245, 200508
  940. Multiple carcinoid tumors of the ileum preoperatively diagnosed by enteroscopy with the double-balloon technique, GASTROINTESTINAL ENDOSCOPY, 62(2), 315-318, 200508
  941. Hepatitis C virus core protein modulates fatty acid metabolism and thereby causes lipid accumulation in the liver, DIGESTIVE DISEASES AND SCIENCES, 50(7), 1361-1371, 200507
  942. Quantitative analysis of lymphangiogenic markers for predicting metastasis of human gastric carcinoma to lymph nodes, INTERNATIONAL JOURNAL OF CANCER, 115(3), 388-392, 20050620
  943. Effect of famotidine on recurrent bleeding after successful endoscopic treatment of bleeding peptic ulcer, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21, 73-78, 200506
  944. Effect of long-term half-dose famotidine therapy on corpus gastritis in peptic ulcer disease, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21, 99-104, 200506
  945. Clinical features of gastric cancer discovered after successful eradication of Helicobacter pylori: results from a 9-year prospective follow-up study in Japan, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21(9), 1121-1126, 20050501
  946. Angiotensin II participates in hepatic inflammation and fibrosis through MCP-1 expression, DIGESTIVE DISEASES AND SCIENCES, 50(5), 942-948, 200505
  947. Ablation of ventricular tachycardia originating from the right ventricle associated with scleroderma cardiomyopathy., J Arrhythmia, 21(5), 542-545, 20050401
  948. Angiotensin II type I receptor blocker and endothelial function in humans: role of nitric oxide and oxidative stress., Curr.Med.Chem, 3(2), 133-148, 20050401
  949. Relationship between histopathological features and type V pit pattern determined by magnifying videocolonoscopy in early colorectal carcinoma, Dig Endos, 17, 117-122, 20050401
  950. The nicorandil-induced vasodilation in humans is inhibited by miconazole, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 45(4), 290-294, 200504
  951. Morphological changes in human gastric tumours after eradication therapy of Helicobacter pylori in a short-term follow-up, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21(5), 559-566, 20050301
  952. A nuclear receptor ligand down-regulates cytosolic phospholipase A(2) expression to reduce bile acid-induced cyclooxygenase 2 activity in cholangiocytes: Implications of anticarcinogenic action of farnesoid X receptor agonists, DIGESTIVE DISEASES AND SCIENCES, 50(3), 514-524, 200503
  953. G to A hypermutation of hepatitis B virus, HEPATOLOGY, 41(3), 626-633, 200503
  954. Ubquitin-interacting motifs of epsin are involved in the regulation of insulin-dependent endocytosis, JOURNAL OF BIOCHEMISTRY, 137(3), 355-364, 200503
  955. Effects of angiotensin II on the expression of MCP-1 in hepatic stellate line LI90, Japanese Pharmaology and Therapeutics, 32, 143-5, 20050201
  956. Molecular evolutionaly analyses implicate injecthion treatment for schistosomiasis in the initial hepatitis C epidemics in japan, Journal of Hepatology, 42, 47-53, 20050101
  957. Superficial type serrated adenoma in ulcerative colitis resected by endoscopic submucosal dissection, Dig Endosc, 17, S49-S52, 20050101
  958. A case of congenital absence of the portal vein, HEPATOLOGY RESEARCH, 31(1), 43-47, 200501
  959. A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer, JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 131(1), 19-25, 200501
  960. Eradication of Helicobacter pylori increases the incidence of hyperlipidaemia and obesity in peptic ulcer patients, DIGESTIVE AND LIVER DISEASE, 37(1), 39-43, 200501
  961. Infliximab therapy for Crohn's disease in a patient with chronic hepatitis B, DIGESTIVE DISEASES AND SCIENCES, 50(1), 163-166, 200501
  962. Molecular evolutionary analyses implicate injection treatment for schistosomiasis in the initial hepatitis C epidemics in Japan, JOURNAL OF HEPATOLOGY, 42(1), 47-53, 200501
  963. Single dose of OCH improves mucosal T helper type 1/T helper type 2 cytokine balance and prevents experimental colitis in the presence of v alpha 14 natural killer T cells in mice, INFLAMMATORY BOWEL DISEASES, 11(1), 35-41, 200501
  964. Suppression of macrophage infiltration inhibits activation of hepatic stellate cells and liver fibrogenesis in rats, GASTROENTEROLOGY, 128(1), 138-146, 200501
  965. Vascular function in patients with lower extremity peripheral arterial disease: a comparison of functions in upper and lower extremities, ATHEROSCLEROSIS, 178(1), 179-185, 200501
  966. A classification system of echogenicity for gastrointestinal neoplasms, DIGESTION, 72(1), 8-12, 2005
  967. Expression of p53 protein in esophageal squamous cell carcinoma: Relation to hypoxia-inducible factor-1 alpha, angiogenesis and apoptosis, PATHOBIOLOGY, 72(4), 179-185, 2005
  968. Involvement of proinflammatory cytokines IL-1 beta and IL-6 in progression of human gastric carcinoma, ANTICANCER RESEARCH, 25(2A), 709-713, 2005
  969. Loss of heterozygosity on chromosome 10p14-p15 in colorectal carcinoma, PATHOBIOLOGY, 72(4), 220-224, 2005
  970. Epigenetic inactivation of SOCS-1 by CpG island hypermethylation in human gastric carcinoma, INTERNATIONAL JOURNAL OF CANCER, 112(6), 1003-1009, 20041220
  971. Single nucleotide polymorphism in the hypoxia-inducible factor-1 alpha gene in colorectal carcinoma, ONCOLOGY REPORTS, 12(5), 1033-1037, 200411
  972. Apolipoprotein E phenotype affects the malondialdehyde-modified LDL concentration and forearm endothelial function in postmenopausal women, CLINICAL ENDOCRINOLOGY, 61(5), 619-625, 200411
  973. Magnifying colonoscopic features of ulcerative colitis reflect histologic inflammation, INFLAMMATORY BOWEL DISEASES, 10(6), 737-744, 200411
  974. Effect of edaravone, a novel free radical scavenger, on endothelium-dependent vasodilation in smokers, AMERICAN JOURNAL OF CARDIOLOGY, 94(8), 1070-1073, 20041015
  975. Partial characterization of cytoprotective mechanisms of lecithin against bile salt-induced bile duct damage, JOURNAL OF GASTROENTEROLOGY, 39(10), 955-960, 200410
  976. Concise prediction models of anticancer efficacy of 8 drugs using expression data from 12 selected genes, INTERNATIONAL JOURNAL OF CANCER, 111(4), 617-626, 20040910
  977. Improvement of atrial signal-averaged electrocardiographic abnormalities after radiofrequency catheter ablation in persistent atrial flutter, JAPANESE HEART JOURNAL, 45(5), 761-770, 200409
  978. Expression of hypoxia-inducible factor (HIF)-1alpha is associated with vascular endothelial growth factor expression and tumour angiogenesis in human oesophageal squamous cell carcinoma., Eur J Cancer, 40, 1904-1912, 20040801
  979. Expression of hypoxia-inducible factor (HIF)-1 alpha is associated with vascular endothelial growth factor expression and tumour anglogenesis in human oesophageal squamous cell carcinoma, EUROPEAN JOURNAL OF CANCER, 40(12), 1904-1912, 200408
  980. Frequent loss of heterozygosity on chromosome 10p14-p15 in esophageal dysplasia and squamous cell carcinoma, ONCOLOGY REPORTS, 12(2), 333-337, 200408
  981. Immune response in mouse experimental cholangitis associated with colitis induced by dextran sulfate sodium, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 19(8), 910-915, 200408
  982. Relationship between C-reactive protein concetrations and coronary microvascular endothelial function0, Heart, 90, 750-754, 20040701
  983. Chromosomal and microsatellite instability in sporadic gastric cancer, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 19(7), 756-760, 200407
  984. Regulation of vascular endothelial growth factor (VEGF)-C and VEGF-D expression by the organ microenvironment in human colon carcinoma, EUROPEAN JOURNAL OF CANCER, 40(10), 1604-1609, 200407
  985. Relation between C reactive protein concentrations and coronary microvascular endothelial function, HEART, 90(7), 750-754, 200407
  986. Induction of apoptosis by ionizing radiation and CI-1033 in HuCCT-1 cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 319(1), 114-119, 20040618
  987. Chronic gastritis with expression of inducible nitric oxide synthase is associated with high expression of interleukin-6 and hypergastrinaemia, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 19(12), 1309-1314, 20040615
  988. Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma, INTERNATIONAL JOURNAL OF CANCER, 110(2), 212-218, 20040610
  989. Fas and Fas ligand: Expression and soluble circulating levels in bile duct carcinoma, ONCOLOGY REPORTS, 11(6), 1183-1186, 200406
  990. Initial experience with catheter probe US when using a multibending endoscope, GASTROINTESTINAL ENDOSCOPY, 59(7), 889-894, 200406
  991. A single nucleotide polymorphism in the MMP-1 promoter is correlated with histological differentiation of gastric cancer, JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 130(5), 259-265, 200405
  992. Effects of aged garlic extract (AGE) on colorectal adenomas: a double-blinded study, Hiroshima J Med Sci, 53(3--4), 39-45, 20040401
  993. Identification of rare polymerase variants of hepatitis B virus using a two-stage PCR with peptide nucleic acid clamping, JOURNAL OF MEDICAL VIROLOGY, 72(4), 558-565, 200404
  994. Magnifying gastroendoscopy for diagnosis of histologic gastritis in the gastric antrum, DIGESTIVE AND LIVER DISEASE, 36(4), 286-291, 200404
  995. Sonographic detection of longitudinal ulcers in Crohn disease, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 39(4), 322-326, 200404
  996. Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia, CIRCULATION, 109(10), 1215-1218, 20040316
  997. Matrix metalloproteinase-9 contributes to human atrial remodeling during atrial fibrillation, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 43(5), 818-825, 20040303
  998. A case of latent primary biliary cirrhosis, HEPATOLOGY RESEARCH, 28(3), 166-169, 200403
  999. Atrial contraction after surgical isolation of the left atrial posterior wall concomitant with mitral valve replacement, CIRCULATION JOURNAL, 68(3), 204-207, 200403
  1000. Clinical significance of angiopoietin-2 expression at the deepest invasive tumor site of advanced colorectal carcinoma, INTERNATIONAL JOURNAL OF ONCOLOGY, 24(3), 539-547, 200403
  1001. Pathophysiology of nonalcoholic steatohepatitis (NASH)-Relation to adipocytokine and advanced glycation end products., Japanese Pharmaology & Therapeutics, 32, 107-9, 20040201
  1002. Angiogenic switch occurs during the precancerous stage of human esophageal squamous cell carcinoma, ONCOLOGY REPORTS, 11(2), 315-319, 200402
  1003. Clinicopathologic and endoscopic features of colorectal serrated adenoma: differences between polypoid and superficial types, GASTROINTESTINAL ENDOSCOPY, 59(2), 213-219, 200402
  1004. Mutation of the von Hippel-Lindau (VHL) gene in human colorectal carcinoma: Association with cytoplasmic accumulation of hypoxia-inducible factor (HIF)-1 alpha, CANCER SCIENCE, 95(2), 149-153, 200402
  1005. Clinical usefulness of high-frequency ultrasound probes for new invasion depth diagnosis in submucosal colorectal carcinoma, Dig Endosc, 16, S49-S52, 20040101
  1006. Expression of human telomerase reverse transcriptase mRNA in esophageal cancers and precancerous lesions, ONCOLOGY REPORTS, 11(1), 51-55, 200401
  1007. Expression of VEGF-C and VEGF-D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma, CANCER SCIENCE, 95(1), 32-39, 200401
  1008. Gemcitabine suppresses malignant ascites of human pancreatic cancer: Correlation with VEGF expression in ascites, ONCOLOGY REPORTS, 11(1), 73-80, 200401
  1009. Characteristics and trends of clarithromycin-resistant Helicobacter pylori isolates in Japan over a decade, PATHOBIOLOGY, 71(3), 159-163, 2004
  1010. Frequent loss of RUNX3 expression by promoter hypermethylation in gastric carcinoma, PATHOBIOLOGY, 71(3), 137-143, 2004
  1011. Mucin phenotype and background mucosa of intramucosal differentiated-type adenocarcinoma of the stomach, ONCOLOGY, 66(5), 379-387, 2004
  1012. Response of the left anterior descending coronary artery to Acetylcholine in patients with chest pain and angiographically normal coronary arteries, AMERICAN JOURNAL OF CARDIOLOGY, 92(12), 1394-1398, 20031215
  1013. Mnk1 is required for angiotensin II - Induced protein synthesis in vascular smooth muscle cells, CIRCULATION RESEARCH, 93(12), 1218-1224, 20031212
  1014. Promoter methylation of cyclin D2 gene in gastric carcinoma, INTERNATIONAL JOURNAL OF ONCOLOGY, 23(6), 1663-1670, 200312
  1015. Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes, DIGESTIVE DISEASES AND SCIENCES, 48(12), 2315-2322, 200312
  1016. Helicobacter pylori infection influences expression of genes related to angiogenesis and invasion in human gastric carcinoma cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 311(4), 809-814, 20031128
  1017. Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 12(4), 437-442, 200310
  1018. Clinical significance of thrombospondin-1 expression in relation to vascular endothelial growth factor and interleukin-10 expression at the deepest invasive tumor site of advanced colorectal carcinoma, INTERNATIONAL JOURNAL OF ONCOLOGY, 23(4), 901-911, 200310
  1019. Disruption of the type 2 dopamine receptor gene causes a sodium-dependent increase in blood pressure in mice, AMERICAN JOURNAL OF HYPERTENSION, 16(10), 853-858, 200310
  1020. Prevalence of Helicobacter pylori resistance to clarithromycin and metronidazole determined by 23S ribosomal RNA and rdxA gene analyses in Hiroshima, Japan, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 18(10), 1202-1207, 200310
  1021. The promoter methylation status of the DNA repair gene O-6-methylguanine-DNA methyltransferase in ulcerative colitis, VIRCHOWS ARCHIV, 443(4), 518-523, 200310
  1022. Does intragastric nitrite concentration reflect gastric carcinogenesis in Japanese Helicobacter pylori-infected patients?, DIGESTIVE DISEASES AND SCIENCES, 48(9), 1730-1736, 200309
  1023. Gastric juice nitrite and vitamin C in patients with gastric cancer and atrophic gastritis: is low acidity solely responsible for cancer risk?, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 15(9), 987-993, 200309
  1024. Necessity of multiple gastric biopsies from different sites for detection of clarithromycin-resistant Helicobacter pylori strains, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(9), 942-946, 200309
  1025. p53 expression, K-ras gene mutation and microsatellite instability in gastric B-cell lymphomas, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 18(9), 1047-1053, 200309
  1026. AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl4, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 308(1), 177-183, 20030815
  1027. Effect of different intensities of exercise on endothelium-dependent vasodilation in humans - Role of endothelium-dependent nitric oxide and oxidative stress, CIRCULATION, 108(5), 530-535, 20030805
  1028. Impact of aging on the development of hepatocellular carcinoma in patients with hepatitis C virus infection in Japan, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(8), 894-900, 200308
  1029. Myocardial bridging increases the risk of coronary spasm, CLINICAL CARDIOLOGY, 26(8), 377-383, 200308
  1030. Somatic mutation of mitochondrial DNA in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 12(2), 169-174, 200308
  1031. Low body mass index is a risk factor for impaired endothelium-dependent vasodilation in humans: Role of nitric oxide and oxidative stress, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 42(2), 256-263, 20030716
  1032. Food deprivation enhances somatostatin and somatostatin receptor subtype expression in rat colon, REGULATORY PEPTIDES, 114(2-3), 167-173, 20030715
  1033. The specific expression of Hypoxia Inducible Factor-1 alpha in human gastric mucosa induced by nonsteroidal anti-inflammatory drugs, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 18, 90-98, 200307
  1034. Natural histories of hepatitis C virus infection in men and women simulated by the Markov model, JOURNAL OF MEDICAL VIROLOGY, 70(3), 378-386, 200307
  1035. Long-term observation of reflux oesophagitis developing after Helicobacter pylori eradication therapy, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 17(12), 1529-1534, 20030615
  1036. Expression of hypoxia-inducible factor-l alpha is associated with tumor vascularization in human colorectal carcinoma, INTERNATIONAL JOURNAL OF CANCER, 105(2), 176-181, 20030610
  1037. Inhibition of cholesterol crystallization under bilirubin deconjugation: partial characterization of mechanisms whereby infected bile accelerates pigment stone formation, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1632(1-2), 48-54, 20030610
  1038. Unique reciprocal changes of hepatocellular membrane transporter expression and fluidity in rats with selective biliary obstruction, HEPATOLOGY RESEARCH, 26(2), 157-163, 200306
  1039. Expressions of angiogenic factors in pancreatic ductal carcinoma: A correlative study with clinicopathologic parameters and patient survival, PANCREAS, 26(4), 344-349, 200305
  1040. Nodular gastritis in adults is caused by Helicobacter pylori infection, DIGESTIVE DISEASES AND SCIENCES, 48(5), 968-975, 200305
  1041. PDE5 inhibitor sildenafil citrate augments endothelium-dependent vasodilation in smokers, HYPERTENSION, 41(5), 1106-1110, 200305
  1042. Smoking activates Rho-kinase in smooth muscle cells of forearm vasculature in humans, HYPERTENSION, 41(5), 1102-1105, 200305
  1043. Comparison of forearm endothelial function between premenopausal and postmenopausal women with or without hypercholesterolemia, MATURITAS, 44(4), 307-315, 20030425
  1044. Depressed-type, early duodenal carcinoma(carcinoma in situ) treated by endoscopic mucosal resection, J. Gastroenterol., 38(8), 813-815, 20030401
  1045. Expression of hyposia-inducible factor-1 alpha is associated with tumor vascularization in human colorectal carcinoma, Int J Cancer, 105(2), 176-181, 20030401
  1046. Expression of vascular endothelial growth facter and angiogenesis in gastrointestinal stromal tumor of the stomach, Oncology, 64(3), 266-274, 20030401
  1047. Minute depressed colon cancer with submucosal invasion, Gastrointest Endosc, 57(4), 564-565, 20030401
  1048. Nondular gastritis in adults is caused by Helicobacter pylori ingfection, Dig Dis Sci, 48(5), 968-975, 20030401
  1049. Prominent J wave and ST segment elevation: Serial electrocardiographic changes in accidental hypothermia, Journal of cardiovasuclar electrophysiology, 14(2), 223, 20030401
  1050. Isolated granulomatous gastritis successfully treated by Helicobacter pylori eradication: a possible association between granulomatous gastritis and Helicobacter pylori, JOURNAL OF GASTROENTEROLOGY, 38(4), 371-375, 200304
  1051. Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human gastric carcinomas, INTERNATIONAL JOURNAL OF ONCOLOGY, 22(4), 773-778, 200304
  1052. Potential involvement of IL-8 and its receptors in the invasiveness of pancreatic cancer cells, INTERNATIONAL JOURNAL OF ONCOLOGY, 22(4), 765-771, 200304
  1053. Serum pepsinogen concentration as a marker of Helicobacter pylori infection and the histologic grade of gastritis; evaluation of gastric mucosa by serum pepsinogen levels, JOURNAL OF GASTROENTEROLOGY, 38(4), 332-338, 200304
  1054. Significance of an exaggerated meal-stimulated gastrin response in pathogenesis of Helicobacter pylori-negative duodenal ulcer, DIGESTIVE DISEASES AND SCIENCES, 48(4), 644-651, 200304
  1055. A comparison of low-dose and standard-dose oral estrogen on forearm endothelial function in early postmenopausal women, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 88(3), 1303-1309, 200303
  1056. Choleretic action of diosgenin is based upon the increases in canalicular membrane fluidity and transporter activity mediating bile acid independent bile flow, HEPATOLOGY RESEARCH, 25(3), 287-295, 200303
  1057. Giant gastric folds: Differential diagnosis at US, RADIOLOGY, 226(3), 686-690, 200303
  1058. Screening of genes specifically activated in the pancreatic juice ductal cells from the patients with pancreatic ductal carcinoma, CANCER SCIENCE, 94(3), 263-270, 200303
  1059. Autonomic nerve dysfunction is closely associated with the abnormalities of esophageal motility in reflux esophagitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(2), 159-163, 200302
  1060. Helicobacter pylori infection influences tumor growth of human gastric carcinomas, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(2), 153-158, 200302
  1061. Impaired gallbladder mucosal function in aged gallstone patients suppresses gallstone recurrence after successful extracorporeal shockwave lithotripsy, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 18(2), 157-161, 200302
  1062. Leptin causes nitric-oxide independent coronary artery vasodilation in humans, HYPERTENSION RESEARCH, 26(2), 147-152, 200302
  1063. Small rectal carcinoid with lymph node metastasis diagnosed prior to treatment, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 15(2), 195-197, 200302
  1064. Cardiac angiotensin II type 2 receptor activates the kinin/NO system and inhibits fibrosis, HYPERTENSION, 41(1), 99-107, 200301
  1065. Hydrophilic bile salts have a cytoprotective effect against cyclosporine A-induced cholestasis through enhanced canalicular membrane fluidity and transporter activity, HEPATOLOGY RESEARCH, 25(1), 38-47, 200301
  1066. Frequent loss of heterozygosity on chromosome 10p15, a putative telomerase repressor/senescence gene locus, in gastric cancer, ONCOLOGY REPORTS, 10(5), 1297-1299, 2003
  1067. Prognostic value of p53 and Ki-67 expression in resected or biopsy specimens of bile duct carcinoma, ONCOLOGY REPORTS, 10(5), 1091-1096, 2003
  1068. Clinicopathologic features and endoscopic resection of early primary nonampullary duodenal carcinoma, JOURNAL OF CLINICAL GASTROENTEROLOGY, 37(5), 381-386, 2003
  1069. Somatic mutation in mitochondrial DNA and nuclear microsatellite instability in gastric cancer, ONCOLOGY REPORTS, 10(6), 1837-1841, 2003
  1070. Expression of fibroblast growth factor receptor genes in human hepatoma-derived cell lines, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 39(7), 321-328, 2003
  1071. Hypoxia-inducible factor-1 alpha expression and angiogenesis in gastrointestinal stromal tumor of the stomach, ONCOLOGY REPORTS, 10(4), 797-802, 2003
  1072. Clinical significance of angiogenic factor expression at the deepest invasive site of advanced colorectal carcinoma, ONCOLOGY, 64(1), 61-73, 2003
  1073. Expression of vascular endothelial growth factor and angiogenesis in gastrointestinal stromal tumor of the stomach, ONCOLOGY, 64(3), 266-274, 2003
  1074. Rare quasispecies in the YMDD motif of hepatitis B virus detected by polymerase chain reaction with peptide nucleic acid clamping, INTERVIROLOGY, 46(6), 355-361, 2003
  1075. Circadian variation of blood pressure and endothelial function in patients with essential hypertension: A comparison of dippers and non-dippers, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 40(11), 2039-2043, 20021204
  1076. A frameshift mutation of beta subunit of epithelial sodium channel in a case of isolated Liddle syndrome, JOURNAL OF HYPERTENSION, 20(12), 2379-2382, 200212
  1077. Mechanisms responsible for vasodilation upon magnesium infusion in vivo: Clinical evidence, MAGNESIUM RESEARCH, 15(3-4), 241-246, 200212
  1078. Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human esophageal squamous cell carcinomas, INTERNATIONAL JOURNAL OF CANCER, 102(3), 220-224, 20021120
  1079. Effect of alcohol consumption on endothelial function in men with coronary artery disease, ATHEROSCLEROSIS, 165(1), 145-152, 200211
  1080. Irsogladine malate up-regulates gap junctional intercellular communication between pancreatic cancer cells via PKA pathway, PANCREAS, 25(4), 373-377, 200211
  1081. Hormone replacement effects on endothelial function measured in the forearm resistance artery in normocholesterolemic and hypercholesterolemic postmenopausal women, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 87(10), 4634-4641, 200210
  1082. Human telomerase reverse transcriptase, p53 and Ki-67 expression and apoptosis in colorectal serrated adenoma, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(10), 1194-1200, 200210
  1083. Clinical characteristics and natural history of patients with low-grade reflux esophagitis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 17(9), 949-954, 200209
  1084. Combination of transcatheter arterial chemoembolization using cisplatin-lipiodol suspension and percutaneous ethanol injection for treatment of advanced small hepatocellular carcinoma, AMERICAN JOURNAL OF SURGERY, 184(3), 284-290, 200209
  1085. Nicorandil-induced preconditioning as evidenced by troponin T measurements after coronary angioplasty in patients with stable angina pectoris, JAPANESE HEART JOURNAL, 43(5), 443-453, 200209
  1086. Advanced colorectal carcinoma smaller than 10 mm in maximum diameter with special reference to clinicopathologic and molecular features: a report of 3 cases, GASTROINTESTINAL ENDOSCOPY, 56(2), 299-303, 200208
  1087. Helicobacter pylori eradication therapy improves atrophic gastritis and intestinal metaplasia: a 5-year prospective study of patients with atrophic gastritis, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 16(8), 1449-1456, 200208
  1088. p53 codon 72 polymorphism in gastric cancer susceptibility in patients with Helicobacter pylori-associated chronic gastritis, INTERNATIONAL JOURNAL OF CANCER, 100(3), 304-308, 20020720
  1089. Vascular endothelial growth factor-C expression predicts lymph node metastasis of human gastric carcinomas invading the submucosa, EUROPEAN JOURNAL OF CANCER, 38(10), 1413-1419, 200207
  1090. Preconditioning effect during coronary angioplasty in patients with stable angina pectoris, INTERNAL MEDICINE, 41(7), 509-515, 200207
  1091. Endothelial function and oxidative stress in renovascular hypertension, NEW ENGLAND JOURNAL OF MEDICINE, 346(25), 1954-1962, 20020620
  1092. Evaluation of esophageal motility by endosonography using a miniature ultrasonographic probe in patients with reflux esophagitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(6), 674-678, 20020601
  1093. Evaluation of gastric emptying measured with the C-13-octanoic acid breath test in patients with functional dyspepsia comparison with ultrasonography, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(6), 662-666, 20020601
  1094. Management of chronic hepatitis C and prevention of hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY, 37, 69-73, 200206
  1095. Balloon-occluded retrograde transvenous obliteration of gastric fundal varices with hemorrhage, AMERICAN JOURNAL OF ROENTGENOLOGY, 178(5), 1167-1174, 200205
  1096. Implication of anti-parietal cell antibody levels in gastrointestinal diseases, including gastric carcinogenesis, DIGESTIVE DISEASES AND SCIENCES, 47(5), 1080-1085, 200205
  1097. Preoperative assessment of gastric cancer vascularity by flash echo imaging, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(5), 608-612, 200205
  1098. Severity of hypertension affects improved resistance artery endothelial function by angiotensin-converting enzyme inhibition, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 39(5), 668-676, 200205
  1099. Hepatic hydroxylation of bile acids and chronic liver diseases: do transporters play a mechanistic role?, 20020401
  1100. Single administration of ecabet sodium diminishes the level of delta-(13) Co(2) in urea breath test, J GastroenterolM., 37(8), 674-675, 20020401
  1101. A low-calorie diet improves endothelium-dependent vasodilation in obese patients with essential hypertension, AMERICAN JOURNAL OF HYPERTENSION, 15(4), 302-309, 200204
  1102. High incidence of B-cell monoclonality in follicular gastritis: a possible association between follicular gastritis and MALT lymphoma, VIRCHOWS ARCHIV, 440(4), 376-380, 200204
  1103. Long-term rebamipide therapy improves Helicobacter pylori-associated chronic gastritis, DIGESTIVE DISEASES AND SCIENCES, 47(4), 862-867, 200204
  1104. Nicorandil enhances myocardial tolerance to ischemia without progressive collateral recruitment during coronary angioplasty, CIRCULATION JOURNAL, 66(4), 317-322, 200204
  1105. Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals, AMERICAN JOURNAL OF HYPERTENSION, 15(4), 326-332, 200204
  1106. Cigarette smoking promotes atrophic gastritis in Helicobacter pylori-positive subjects, DIGESTIVE DISEASES AND SCIENCES, 47(3), 675-681, 200203
  1107. Leptin causes vasodilation in humans, HYPERTENSION RESEARCH, 25(2), 161-165, 200203
  1108. Role of anti-parietal cell antibody in Helicobacter pylori-associated atrophic gastritis: Evaluation in a country of high prevalence of atrophic gastritis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(3), 287-293, 200203
  1109. Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia, HEART, 87(3), 264-269, 200203
  1110. Estrogen replacement suppresses function of thrombin stimulated platelets by inhibiting Ca2+ influx and raising cyclic adenosine monophosphate, CARDIOVASCULAR RESEARCH, 53(3), 634-641, 20020215
  1111. Less hydrophobic phosphatidylcholine species simplify biliary vesicle morphology, but induce bile metastability with a broad spectrum of crystal forms, BIOCHEMICAL JOURNAL, 362, 105-112, 20020215
  1112. K-ras mutation in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer, INTERNATIONAL JOURNAL OF CANCER, 97(5), 562-566, 20020210
  1113. Excess norepinephrine impairs both endothelium-dependent and -independent vasodilation in patients with pheochromocytoma, HYPERTENSION, 39(2), 513-518, 200202
  1114. Helicobacter pylori infection increases serum nitrate and nitrite more prominently than serum pepsinogens, HELICOBACTER, 7(1), 9-13, 200202
  1115. Serological comparison of serum pepsinogen and antiparietal cell antibody levels between Japanese and German patients, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 14(2), 123-127, 200202
  1116. Tetrahydrobiopterin improves coronary endothelial function, but does not prevent coronary spasm in patients with vasospastic angina, CIRCULATION JOURNAL, 66(1), 58-62, 200201
  1117. Combination therapy of low-dose medroxyprogesterone acetate and oral estrogen does not affect endothelial function in the forearms of postmenopausal women, MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 9(5), 360-366, 2002
  1118. Determining depth of invasion by VN pit pattern analysis in submucosal colorectal carcinoma, ONCOLOGY REPORTS, 9(5), 1005-1008, 2002
  1119. Clinical significance of angiogenesis in rectal carcinoid tumors, ONCOLOGY REPORTS, 9(3), 489-494, 2002
  1120. Renal endothelial dysfunction and hypertension, JOURNAL OF DIABETES AND ITS COMPLICATIONS, 16(1), 103-107, 2002
  1121. Clinical significance of vascular endothelial growth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma, ONCOLOGY, 62(2), 157-166, 2002
  1122. Does bilirubin play a role in the pathogenesis of both cholesterol and pigment gallstone formation? Direct and indirect influences of bilirubin on bile lithogenicity, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1534(2-3), 78-84, 20011230
  1123. Endothelial dysfunction is an independent factor responsible for vasospastic angina, CLINICAL SCIENCE, 101(6), 707-713, 200112
  1124. Microsatellite instability is a genetic marker for the development of multiple gastric cancers, INTERNATIONAL JOURNAL OF CANCER, 95(6), 350-353, 20011120
  1125. Usefulness of flow-mediated dilation of the brachial artery and/or the intima-media thickness of the carotid artery in predicting coronary narrowing in patients suspected of having coronary artery disease, AMERICAN JOURNAL OF CARDIOLOGY, 88(10), 1147-1151, 20011115
  1126. Bile-salt hydrophobicity is a key factor regulating rat liver plasma-membrane communication: relation to bilayer structure, fluidity and transporter expression and function, BIOCHEMICAL JOURNAL, 359, 605-610, 20011101
  1127. Extracorporeal ultrasound is an effective diagnostic alternative to endoscopic ultrasound for gastric submucosal tumours, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 36(11), 1222-1226, 200111
  1128. Sodium chloride loading does not alter endothelium-dependent vasodilation of forearm vasculature in either salt-sensitive or salt-resistant patients with essential hypertension, HYPERTENSION RESEARCH, 24(6), 711-716, 200111
  1129. Calorie restriction reduced blood pressure in obesity hypertensives by improvement of autonomic nerve activity and insulin sensitivity, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 38, S69-S74, 200110
  1130. Effect of obesity on endothelium-dependent, nitric oxide-mediated vasodilation in normotensive individuals and patients with essential hypertension, AMERICAN JOURNAL OF HYPERTENSION, 14(10), 1038-1045, 200110
  1131. MUC1 and cathepsin D expression in early colorectal carcinoma showing V type pit pattern, INTERNATIONAL JOURNAL OF ONCOLOGY, 19(4), 665-672, 200110
  1132. Clinicopathological significance of vascular endothelial growth factor (VEGF)-C in human esophageal squamous cell carcinomas, INTERNATIONAL JOURNAL OF CANCER, 93(5), 662-666, 20010901
  1133. A low C-13-urea breath test value is associated with increased risk of gastric cancer, JOURNAL OF GASTROENTEROLOGY, 36(9), 601-605, 200109
  1134. Expression of telomeric repeat binding factor 1 and 2 and TRF1-interacting nuclear protein 2 in human gastric carcinomas, INTERNATIONAL JOURNAL OF ONCOLOGY, 19(3), 507-512, 200109
  1135. Randomized controlled clinical trial of lymphoblastoid interferon-alpha for chronic hepatitis C, HEPATOLOGY RESEARCH, 21(1), 55-66, 200109
  1136. Interleukin 8 and vascular endothelial growth factor - prognostic factors in human gastric carcinomas?, EUROPEAN JOURNAL OF CANCER, 37(12), 1482-1487, 200108
  1137. Nonselective cation channel as a Ca2+ influx pathway in pepsinogen-secreting cells of bullfrog esophagus, AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 281(2), G333-G341, 200108
  1138. Clinicopathologic features and endoscopic treatment of superficially spreading colorectal neoplasms larger than 20 mm, GASTROINTESTINAL ENDOSCOPY, 54(1), 62-66, 200107
  1139. Clinicopathological features of gastric mucosa-associated lymphoid tissue lymphoma: A comparison with diffuse large B-cell lymphoma without a mucosa-associated lymphoid tissue lymphoma component, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 16(7), 734-739, 200107
  1140. Dose-dependent conjugation of sulfobromophthalein and hepatic transit time in bile fistula rats - Role of the microtubule-dependent vesicle pathway, DIGESTIVE DISEASES AND SCIENCES, 46(6), 1285-1289, 200106
  1141. Evaluation of quantitative measurements of hepatitis C virus RNA to predict sustained response to interferon by genotype, JOURNAL OF VIROLOGICAL METHODS, 95(1-2), 33-45, 200106
  1142. Helicobacter pylori eradication therapy for high-grade mucosa-associated lymphoid tissue lymphomas of the stomach with analysis of p53 and K-ras alteration and microsatellite instability, INTERNATIONAL JOURNAL OF ONCOLOGY, 18(6), 1207-1212, 200106
  1143. Risk factors of hepatitis C virus-related liver cirrhosis in young adults: Positive family history of liver disease and transporter associated with antigen processing 2 (TAP2)*0201 allele, JOURNAL OF MEDICAL VIROLOGY, 64(2), 109-116, 200106
  1144. Is a role of phospholipase A(2) in cholesterol gallstone formation phospholipid species-dependent?, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1532(1-2), 51-59, 20010531
  1145. Non-dipper phenomenon in essential hypertension is related to blunted nocturnal rise and fall of sympatho-vagal nervous activity and progress in retinopathy, AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, 88(3), 181-186, 20010514
  1146. Angiotensin II type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin II type 1 receptor antagonist, FEBS LETTERS, 495(3), 197-200, 20010427
  1147. Angiotensin (]G0002[) type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin (]G0002[) type 1 receptor antagonist, FEBS Lett, 495, 197-200, 20010401
  1148. Diagnosis of invasion depth in early colorectal carcinoma by pit pattern analysis with magnifying endoscopy, Digestive Endoscopy, 13, S2-S5, 20010401
  1149. Effect of for antihypertensives on reactive hypermia in essential hypertension, Cardiology Review, 18(4), 31-39, 20010401
  1150. Efficacy of IFN therapy based on duration period of negative HCV-RNA during IFN administration, Hepatol Res, 19, 22-300, 20010401
  1151. Long-term interferon therapy for 1 year or longer reduces the hepatocellular carcinogenesis rate in patients with liver cirrhosis caused by hepatitis C virus: a pilot study, J Gastroenterol Hepatol., 16(4), 406-415, 20010401
  1152. Risk factors of hepatitis C virus-related liver cirrhosis in young adults: positive family history of liver disease and transporter associated with antigen processing 2(TAP2)*0201 Allele., J Med Virol, 64, 109-116, 20010401
  1153. Twice-daily administration of interferon-beta for chronic hepatitis C is not superior to a once-daily regimen, J. Gastroenterol, 36, 242-247, 20010401
  1154. Cyclosporin A reduces canalicular membrane fluidity and regulates transporter function in rats, BIOCHEMICAL JOURNAL, 354, 591-596, 20010315
  1155. Effect of estrogen replacement therapy on endothelial function in peripheral resistance arteries in normotensive and hypertensive postmenopausal women, HYPERTENSION, 37(2), 651-657, 200102
  1156. Lamivudine therapy for spontaneously occurring severe acute exacerbation in chronic hepatitis B virus infection: A preliminary study, AMERICAN JOURNAL OF GASTROENTEROLOGY, 96(2), 557-562, 200102
  1157. Pathogenic significance and organic virus levels in patients infected with TT virus, INTERVIROLOGY, 44(5), 291-297, 2001
  1158. Reduction in the incidence of Helicobacter pylori-associated carcinoma in Japanese young adults, ONCOLOGY REPORTS, 8(3), 633-636, 2001
  1159. c-myc gene mutation in gastric mucose-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphoma, ONCOLOGY REPORTS, 8(2), 289-292, 2001
  1160. Microsatellite instability at D18S61 is associated with no regression of gastric mucosa-associated lymphoid tissue lymphoma after Helicobacter pylori eradication, ONCOLOGY REPORTS, 8(2), 293-297, 2001
  1161. Activation of peroxisome proliferator-activated receptor gamma inhibits the growth of human pancreatic cancer, PATHOBIOLOGY, 69(5), 258-265, 2001
  1162. Expression of MRE11 complex (MRE11, RAD50, NBS1) and hRap1 and its relation with telomere regulation, telomerase activity in human gastric carcinomas, PATHOBIOLOGY, 69(4), 219-224, 2001
  1163. Association of amino acid sequence in the PKR-eIF2 phosphorylation homology domain and response to interferon therapy, HEPATOLOGY, 32(5), 1138-1144, 200011
  1164. Distinction between chronic hepatitis and liver cirrhosis in patients with hepatitis C virus infection. Practical discriminant function using common laboratory data, Hepatol Res, 18(3), 252-266, 20000401
  1165. Fluctuation patterns of HCV-RNA serum level in patients with chronic hepatitis C, J. Gastroenterol., 35(3), 221-225, 20000401
  1166. Incidence of primary liver cancer-cholangiocellular type in Japanese patients with hepatitis C virus related cirrhosis, Cancer, 88, 2471-2477, 20000401
  1167. Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor-A prospective randomized study of hepatitis C virus-related liver cancer., Hepatology, 32(2), 436-438, 20000401
  1168. Progressive and sufficient decrease of hepatitis B core antibody can predict the disappearance of hepatitis B virus DNA in Japanese patients with hepatitis B surface antigen clearance, J. Gastroenterol., 35(10), 753-757, 20000401
  1169. Relationship between five-year histological outcome and serial changes in serum alanine aminotransferase in patients with biochemical and virological relapse after interferon treatment for chronic hepatitis C, Intervirol, 43, 174-179, 20000401
  1170. A device for simultaneous application of sclerotherapy and endoscopic ligation for management of esophageal varices, Dig.Endosc, 11, 363-365, 19990401
  1171. Chronic liver disease in the extremely elderly of 80 years or more: clinical characteristics, prognosis and patient survival analysis, J Hepatol, 31, 860-866, 19990401
  1172. Clinical and virological features of chronic hepatitis C carriers with normal alanine aminotransferase levels despite positive serum HCV-RNA after interferon therapy, J. Gastroenterol., 34, 594-599, 19990401
  1173. Combined ursodeoxycholic acid glycyrrhizin therapy for chronic hepatitis C virus infection: a randomized controlled trial in 170 patients, Eur J Gastroen Hepat, 11, 1077-1083, 19990401
  1174. Effect of arterial administration of a high-molecular weight antitumor agent,styrene maleic acid neocarzinostatin,in embolization-resistant liver cancer, Int. J. Clin. Oncol., 14, 148-155, 19990401
  1175. Effect of interferon therapy on hepatocellular carcinogenesis in patients with chronic hepatitis type C: A long-term observation study of 1,643 patients using statistical bias correction with proportional hazard analysis, Hepatology, 29(4), 1124-1130, 19990401
  1176. Efficacy and changes of the nonstructural 5A gene by prolonged interferon therapy for patients with hepatitis C virus (HCV) genotype1b and a high level of serum HCV-RNA, Intern Med, 38, 19990401
  1177. Enzyme-linked immunosorbent assay to detect hepatitis C virus serological groups 1to 6, J. Gastroenterol., 34, 505-509, 19990401
  1178. Fluctuations of hepatitis C virus load are not related to amino acid substitutions in hypervariable region 1 and interferon sensitivity determining region, J Med Virol, 58, 247-255, 19990401
  1179. Histological changes in liver biopsies after one year of lamivudine treatment in patients with chronic hepatitis B infection, J Hepatol, 30, 743-748, 19990401
  1180. Prevalence of TT virus before and after blood transfusion in patients with chronic liver disease treated surgically for hepatocellular carcinoma, J Gastroenterol Hepatol., 14, 358-363, 19990401
  1181. Susceptibility of TT virus to interferon therapy, J. Gen. Virol., 80, 631-634, 19990401
  1182. Time course of histological changes in patients with a sustained biochemical and virological response to corticosteroid withdrawal therapy for chronic hepatitis B, Am J Gastroenterol, 94, 3304-3309, 19990401
  1183. A randomized controlled trial of interferon-alpha in patients with cirrhosis caused by 2a/2b genotype hepatitis C virus, J Hepatol, 27(5), 910-912, 19980401
  1184. Biochemical and histological features of hepatitis G virus infection, J Gastroenterol Hepatol., 13, 767-772, 19980401
  1185. Deletions in the hepatitis B virus core gene may influence the clinical outcome in hepatitis B e antigen-positive asymptomatic healthy carriers., Journal of Medical Virology, 56, 287-293, 19980401
  1186. Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients, J Hepatol, 28, 930-938, 19980401
  1187. Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy., Hepatology, 27, 1711-1716, 19980401
  1188. Glomerulonephritis in autopsy cases with hepatitis C virus infection, Internal Med., 37(10), 836-840, 19980401
  1189. Interferon decreases hepatocellular carcinogenesis in patients with cirrhosis caused by the hepatitis B virus-A pilot study, Cancer, 82(5), 827-835, 19980401
  1190. Predictive factors in eradicating hepatitis C virus using a relatively small dose of interferon, J Gastroenterol Hepatol., 13, 412-418, 19980401
  1191. Relationship of angiographic finding with neovascular structure detected by immunohistochemical staining of alpha-smooth muscle action in small hepatocellular carcinoma, J Gastroenterol Hepatol., 13, 1266-1273, 19980401
  1192. Relationship of hepatocellular carcinogenesis with precore mutant virus and serum hepatitis B virus DNA concentration. A longitudinal analysis of patients with cirrhosis, Hepatol Res, 10, 142-155, 19980401
  1193. Usefulness of hepatitis C virus RNA counts by second generation HCV bDNA-probe in chronic hepatitis C based on the HCV genotype, J. Gastroenterol., 33(2), 223-228, 19980401
  1194. A prospective randomized administration of 5'-deoxy-5-fluorouridine as adjuvant chemotherapy for hepatocellular carcinoma treated with transcatheter arterial chemoembolization., Am. J. Clin. Oncol., 20(2), 202-208, 19970401
  1195. Effect of arterial administration of a high molecular weight anti-tumor agent, styrene maleic acid neocarzinostain, for multiple small liver cancer-A pilot study, J. Gastroenterol., 32, 513-520, 19970401
  1196. Effect of interferon therapy on viral titers in patients with chronic hepatitis C who are positive for hepatitis GB virus C, J Hepatol, 26, 769-770, 19970401
  1197. Hepatitis G virus infection after blood transfusion in patients with chronic liver disease treated surgically for hepatocellular carcinoma, Hepatol Res, 9(1), 28-36, 19970401
  1198. Nucleotide sequences of hepatitis GB virus C. Identification of highly conserved domains in the 5' noncoding region and detection by polymerase chain reaction, Int Hepatol Commun, 6, 225-232, 19970401
  1199. Pretreatment virus load and multiple amino acid substitutions in the interferon sensitivity-determining region predict the outcome of interferon treatment in patients with chronic genotype 1b hepatitis C virus infection, Hepatology, 25, 745-749, 19970401
  1200. The long term efficacy of glycyrrhizin in chronic hepatitis C patients, Cancer, 79(8), 1494-1500, 19970401
  1201. The superiority of laparoscopic examination in predicting hepatocellular carcinoma after interferon therapy for chronic type C hepatitis, Dig.Endosc, 9(1), 29-33, 19970401
  1202. Time course of histological changes in patients with a sustained biochemical and virological response to interferon-alpha therapy for chronic hepatitis C virus infection., J Hepatol, 27(1), 49-55, 19970401
  1203. A pilot study of corticosteroid priming for lymphoblastoid interferon alpha in patients with chronic hepatitis C, Hepatology, 23, 953-957, 19960401
  1204. Hepatitis C virus subtype 3b infection in a hospital in Japan: Epidemiological study, J. Gastroenterol., 31(6), 801-805, 19960401
  1205. Relationship between pretreatment viremia level and response to interferon alpha therapy in chronic hepatitis C differs in viral type 1 and 2 infections, Digest Dis Sci, 41(10), 1925-1932, 19960401
  1206. Typing six major hepatitis C virus genotypes by polymerase chain reaction using primers derived from nucleotide sequences of the NS5 region, Int Hepatol Commun, 4, 263-267, 19960401
  1207. Genotype, slow decrease in virus titer during interferon treatment and high degree of sequence variability of hypervariable region are indicative of poor response to interferon treatment in patients with chronic hepatitis type C, J Hepatol, 23, 648-653, 19950401
  1208. Genotyping of hepatitis C virus by the polymerase chain reaction: a comparison of two PCR-based methods using core or NS5 primers, Int Hepatol Commun, 4, 67-71, 19950401
  1209. Molecular analysis of intraspousal transmission of hepatitis C virus, J Hepatol, 22, 431-439, 19950401
  1210. Novel hepatitis B variants in sibling carriers positive for antibody to hepatitis B surface antigen, Int Hepatol Commun, 4, 121-125, 19950401
  1211. A prospective randomized evaluation of a compound of Tegafur and Uracil as an adjuvant chemotherapy for hepatocellular carcinoma treated with transcatheter arterial chemoembolization, Am. J. Clin. Oncol., 18(3), 204-210, 19950401
  1212. Diagnosis of hepatocellular carcinoma by concanavalin A affinity electrophoresis of serum alpha-fetoprotein, Cancer, 76(3), 1139-1144, 19950401
  1213. Serial hemodynamic measurements in well-differentiated hepatocellular carcinomas, Hepatology, 21(6), 1530-1534, 19950401
  1214. Usefulness of HCV-RNA counts by the method of HCV-bDNA probe in interferon retreatment for patients with HCV-RNA positive chronic hepatitis C, Int Hepatol Commun, 4(1), 19-25, 19950401
  1215. Antiviral effect of lymphoblastoid IFN-alpha on hepatitis C virus in patients with chronic hepatitis type C, J Gastroen Hepatol, 9, 128-133, 19940401
  1216. Imaging diagnosis of small hepatocellular carcinoma, Hepatology, 20(1), 82-87, 19940401
  1217. Interferon retreatment of nonresponders with HCV-RNA-positive chronic hepatitis C, J. Gastroenterol., 29, 299-304, 19940401
  1218. Nucleotide sequence of hepatitis C virus (type 3b) isolated from a Japanese patient with chronic hepatitis C, J. Gen. Virol., 75, 3623-3628, 19940401
  1219. Prevalence of HCV genotype among patients with chronic liver disease in the Tokyo metropolitan area, J. Gastroenterol., 29, 583-587, 19940401
  1220. Serum des-gamma-carboxyprothrombin concentration determined by the avidin-biotin complex method in small hepatocellular carcinomas, Cancer, 74(11), 2918-2923, 19940401
  1221. Small hepatocellular carcinoma: evaluation of portal blood flow with CT during arterial portography performed with balloon occlusion of the hepatic artery, Radiology, 193, 67-70, 19940401
  1222. The HCV-bDNA probe method for measurement of HCV-RNA counts by HCV genotype, Int Hepatol Commun, 2, 213-217, 19940401
  1223. A proposed system for the nomenclature of hepatitis C viral genotypes., 19940101
  1224. Factors predictive of response to interferon-alpha therapy in hepatitis C virus infection., 19940101
  1225. A multivariate analysis of risk factors for hepatocellular carcinogenesis- A prospective observation of 795 patients with viral and alcoholic cirrhosis, Hepatology, 18(1), 47-53, 19930401
  1226. Diagnosis and follow-up of small hepatocellular carcinoma with selective intraarterial digital subtraction angiography, Hepatology, 17(6), 1003-1007, 19930401
  1227. Effect of lymphoblastoid alfa-interferon in patients with chroni chepatitis C having different genotypic subtype of hepatitis C virus, Gastroenterologia Japonica, 28, 45-47, 19930401
  1228. Factors useful in predicting the response to interferon therapy in chronic hepatitis C, J Gastroen Hepatol, 8, 535-539, 19930401
  1229. Genotypic subtyping of hepatitis C virus, J Gastroenterol Hepatol., 8, 150-156, 19930401
  1230. Risk factors for tumor recurrence and prognosis after curative resection of hepatocellular carcinoma, Cancer, 71(1), 19-25, 19930401
  1231. Alanine aminotransferase and HCV-RNA responses following interferon therapy of HCV-RNA positive chronic hepatitis, Gastroenterologia Japonica, 27(5), 646-651, 19920401
  1232. Effect of interferon administration on serum hepatitis C virus RNA in patients with chronic hepatitis C, Hepatology, 13(6), 1040-1043, 19910401
  1233. Effect of repeated transcatheter arterial embolization on the survival time in patients with hepatocellular carcinoma. An analysis by the proportional hazard model, Cancer, 68(10), 2150-2154, 19910401
  1234. Phyllodes tumor of the prostate: A case report, 19, 299-304, 19890301
  1235. Skeletal Muscle Loss during Tyrosine Kinase Inhibitor Treatment for Advanced Hepatocellular Carcinoma Patients, LIVER CANCER, 9(2), 148-155, 202004
  1236. Predicting atrial fibrillation using a combination of genetic risk score and clinical risk factors, HEART RHYTHM, 17(5), 699-705, 202005
  1237. Pan-cancer analysis of whole genomes, NATURE, 578(7793), 82-+, 20200206
  1238. Population Pharmacokinetics of Glecaprevir/Pibrentasvir in HCV-infected Japanese Subjects in Phase 3 CERTAIN-1 and CERTAIN-2 Trials, JOURNAL OF CLINICAL PHARMACOLOGY, 60(3), 331-339, 202003
  1239. Isolated cardiac metastases of hepatocellular carcinoma after resection: a case report, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(3), 421-427, 202006
  1240. JNJ-4178 (adafosbuvir, odalasvir, and simeprevir) in Japanese patients with chronic hepatitis C virus genotype 1 or 2 infection with or without compensated cirrhosis: the Phase IIa OMEGA-3 study, JOURNAL OF GASTROENTEROLOGY, 55(6), 640-652, 202006
  1241. Serum miR-379 expression is related to the development and progression of hypercholesterolemia in non-alcoholic fatty liver disease, PLOS ONE, 15(2), 20200227
  1242. Diagnostic Yield of Colon Capsule Endoscopy in Detection of Superficial Colorectal Lesions, DIGESTION, 101(3), 262-269, 202005
  1243. Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib, THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 12, 202005

Publications such as books

  1. 2006, Molecular pathologic application as a predictor of lymph node metastasis in submucosal colorectal carcinoma:implication of immunohistochemical alterations at the deepest invasive margin , 2006, 04, 171
  2. 2005, Role of invariant natural killer T cells in the regulation of the inflammatory response in experimental colitis in mice , 2005, 12, 35
  3. 1998, Methods in molecular medicine-hepatitis C protocols. Genotyping hepatitis C virus by type-specific primers for PCR based on NS5 region. , Humana Press, 1998
  4. 1998, Hepatitis C protocols; Genotyping hepatitis C virus by type-specific primers or PCR based on NS5 region , Humana Press, 1998
  5. 1994, Viral hepatitis and liver disease. High virus titer, slow virus decrease, genotype(]G0002[), and sequence variability of E2/NS1 HVR predict poor response to interferon therapy in chronic hepatitis C. , Springer Verlag, 1994
  6. 1994, High virus titer, slow virus decrease, genotypeII, and sequence variability of E2/NS1 HVR predict poor response to interferon therapy in chronic hepatitis C Viral hepatitis and liver disease , Springer Verlag, 1994
  7. 2017, Hepatotos C Virus Treatment, Highly Effective Therapy with Direct Acting Antivirals and Associated Viral Resistance, Springer, 2017
  8. 2017/09/05, Hepatitis B Virus and Liver Desease, Unmet Needs in Basic Research: In Vitro and In Vivo Models, Springer Nature Singapore Pre Ltd., 2018, 2018, Kazuaki Chayama, Nelson Hayes.
  9. 2017/09/30, Management for DAA resistant-associated variants, Management for DAA resistant-associated variants, 2017, 9月
  10. 2017/12, The Liver Cancer Journal, Meeting Report
  11. 2018, Clinics in Gastroenterology, 2018

Invited Lecture, Oral Presentation, Poster Presentation

  1. DAA/PR therapy in Asian HCV patients, 2015/12/04, With Invitation
  2. Hepatitis B mouse model involving CTL, 2015/04/23, Without Invitation
  3. Ombitasvir/Paritaprevir/Ritonavir for treatment of HCV genotype 1b in Japanese patients with or without Cirrhosis: results from GIFT-1, 2015/05/22, Without Invitation
  4. All Oral Direct Acting Antiviral Therapy for Chronic Hepatitis C, 2015/10/17, With Invitation
  5. Circulating Tumor DNA Analysis for HCC., 2015/10/26, With Invitation
  6. All-oral Dual Combination of Daclatasvir plus Asunaprevir Compared with Telaprevir plus Peginterferon Alfa/Ribavirin in Treatment-maive Japanese Patients ChronicallyInfected with HCV Genotype 1b:Results from a Phase 3 Study, chayama kazuaki, 2014/11/11, Without Invitation
  7. Optimizing triple therapy, and IFN/RBV free regimens, chayama kazuaki, 2014/03/12, Without Invitation
  8. Circulating Tumor DNA Analysis for HCC., 2015/10/26, Without Invitation
  9. GIFT-1:Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir in Elderly Japanese Patients, Asian Pacific Association for the Study of the Liver 2016(APASL 2016) (アジア太平洋肝臓病学会議), 2016/02/22, Without Invitation, Tokyo
  10. Chimeric Animal Model, Asian Pacific Association for the Study of the Liver 2016(APASL 2016) (アジア太平洋肝臓病学会議), 2016/02/22, Without Invitation, Tokyo
  11. HCV Treatiment Update-a New Era of All-oral HCV Treatment, The 46th Annual Meeting of GEST and The 25th Annual Meeting of DEST, 2016/03/26, With Invitation, Taipei
  12. A mouse model of human CTL mediated severe acute hepatitis B, 2016/05/20, Without Invitation, Makuhari
  13. Best Strategy for Curing HCV Genotype 1 and 4: East vs. West, 2016 APASL Single Topic Conference on Hepatitis C, 2016/06/11, Without Invitation, Kaohsiung city (Taiwan)
  14. Integrated safety and Tolerability of DCV+ASV in Patients with Chronic HCV Genotype 1b Infection, 2016 APASL Single Topic Conference on Hepatitis C, 2016/06/12, Without Invitation, Kaohsiung (Taiwan)
  15. Practical Therapy of Chronic Hepatitis C, 2016/10/12, Without Invitation, Kyoto
  16. Targeting Host and Viral Interactions: Insights from Mice Model, Asian Pacific Association for the Study of the Liver 2017(APASL 2017), 2017/02/17, With Invitation, Shanghai
  17. Recent Progress in Treatment for Chronic Hepatitis C for Genotype 1, Asian Pacific Association for the Study of the Liver Single Topic Conference(APASL STC), Without Invitation, Nagasaki city
  18. Recent Progress in Treatment for Chronic Hepatitis C for Genotype 1, Asian Pacific Association for the Study of the Liver Single Topic Conference(APASL STC), Without Invitation, Nagasaki
  19. Recent Progress in Treatment for Chronic Hepatitis C for Genotype 1, Asian Pacific Association for the Study of the Liver Single Topic Conference(APASL STC), 2017/04/11, Without Invitation, Nagasaki city
  20. Efficacy and safety of Glecaprevir/Pibrentasvir in Japanese Patients with Chronic GT1 Hepatitis C Virus Infection with and without Cirrhosis, 2017/06/09, Without Invitation, Hiroshima city
  21. Baselin RAS Test: Clinical practice, The Liver Week 2017, 2017/06/23, With Invitation, Korea
  22. Recent Progress in Treatment for Chronic Hepatitis C, APDW2016, 2016/11/05, Without Invitation
  23. chronic hepatitis virus infection and interferon, 2017/10/30, Without Invitation

Patented

  1. Patent, JP5152745, 2012/12/14
  2. Patent
  3. Patent, JP2869759, 1999/01/08
  4. Patent, JP5656159, 2014/12/05
  5. Patent, JP5696317, 2015/02/20
  6. Patent, JP5888668, 2016/02/26
  7. Patent, JP5924644, 2016/04/28
  8. Patent
  9. Patent
  10. Patent
  11. Patent
  12. Patent
  13. Patent
  14. Patent
  15. Patent, 2014/12/05
  16. Patent
  17. Patent
  18. Patent
  19. Patent

Works, etc.

  1. 広島大学ラグビー部顧問,第32回中国四国医科学生ラグビーフットボール大会 広島大学優勝

External Funds

Acceptance Results of Competitive Funds

  1. Research Program on Hepatitis, 2015/04/01, 2016/03/31
  2. Research Program on Hepatitis, 2015/04/01, 2016/03/31
  3. Health and Labour Sciences Research Grants, 2011, 2013
  4. Health and Labour Sciences Research Grants, 2012, 2016
  5. 2001
  6. 2003
  7. 2004
  8. 2004
  9. 2004
  10. 2006
  11. 2005
  12. 2007
  13. 2007
  14. 2008
  15. 2009
  16. 2009
  17. 2010
  18. 2010
  19. KAKENHI, 2014, 2014
  20. KAKENHI, Identification of SNPs on mature micro RNA to analyze origin of miRNA, 2013, 2013
  21. KAKENHI, Analysis of unknown pathogen using human hepatocyte chimeric mouseand massive parallel sequencing, 2012, 2012
  22. KAKENHI, Generation of a mouse model that shows specific features of human diseases., 2010, 2011
  23. KAKENHI, A comprehensive transcriptome analysis of humanized mouse liver using ultra high density cDNA micro array, 2009, 2011
  24. KAKENHI, 2007, 2007
  25. KAKENHI, Production of interferon stimulated gene library and screening of new therapeutic drug for hepatitis viruses, 2006, 2007
  26. KAKENHI, 2003, 2005
  27. KAKENHI, Specification of the factor in a liver cell required for multiplication of hepatitis C virus, 2001, 2003
  28. KAKENHI, Analysis of lamivudine resistance acquisition by hepatitis B virus., 2001, 2003
  29. KAKENHI, Detection of drug resistant mutant hepatitis B virus strain and its clinical application., 1998, 2000
  30. KAKENHI, Interferon resistance of hepatitis C virus, 1994, 1995
  31. Health and Labour Sciences Research Grants, 2014/04/01, 2015/03/31
  32. KAKENHI, 2015, 2016
  33. Research Program on Hepatitis , 2016/04/01, 2017/03/31
  34. Research Program on Hepatitis , 2016/04/01, 2017/03/31
  35. KAKENHI(Grant-in-Aid for Challenging Research (Pioneering)), 2017, 2019
  36. Research Program on Hepatitis , 2017/04/01, 2018/03/31
  37. Research Program on Hepatitis , 2017/04/01, 2018/03/31
  38. 2004/04/01
  39. 2017

Social Activities

Organizing Academic Conferences, etc.

  1. 2000/11
  2. 2001/10
  3. 2001/05
  4. 2001/10
  5. 2001/11
  6. 2001/02
  7. 2001/11
  8. 2001/02
  9. 2001/07
  10. 2001/07
  11. 2001/04
  12. 2001/05
  13. 2001/09
  14. 2001/12
  15. 2001/01
  16. 2009/09
  17. 2011/10
  18. 2012/02
  19. The 2nd Japan-Italy Liver Workshop, 2014/11, 2014/11
  20. The 11th JSH Single Topic Conference, 2014/11
  21. 2014/07
  22. 2016/11
  23. 2015/11, 2015/11
  24. 2017/06, 2017/06
  25. 2016/06, 2016/06
  26. 2017/07, 2017/07

Other Social Contributions

  1. Pancreatic Cancer Expert Meeting, 2017/05/26, 2017/05/26
  2. Academic Workshop by Hiroshima University and Cairo University, Human hepatocyte chimeric mouse model for hepatitis virus studies, 2017/02/21, 2017/02/21