長町 安希子AKIKO NAGAMACHI

Last Updated :2019/12/02

所属・職名
原爆放射線医科学研究所附属放射線先端医学実験施設助教
メールアドレス
nagamachihiroshima-u.ac.jp

基本情報

学位

  • 博士(医学)(広島大学)
  • 修士(薬学)(徳島文理大学)

研究分野

  • 医歯薬学 / 内科系臨床医学 / 血液内科学

所属学会

  • 日本血液学会
  • 日本癌学会

研究活動

学術論文(★は代表的な論文)

  1. The Dynactin Complex Maintains the Integrity of Metaphasic Centrosomes to Ensure Transition to Anaphase, JOURNAL OF BIOLOGICAL CHEMISTRY, 286巻, 7号, pp. 5589-5598, FEB 18 2011
  2. Poly-ADP Ribosylation of Miki by tankyrase-1 Promotes Centrosome Maturation, MOLECULAR CELL, 47巻, 5号, pp. 694-706, SEP 14 2012
  3. Role of Pin1 Protein in the Pathogenesis of Nonalcoholic Steatohepatitis in a Rodent Model, JOURNAL OF BIOLOGICAL CHEMISTRY, 287巻, 53号, pp. 44526-44535, DEC 28 2012
  4. Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7, CANCER CELL, 24巻, 3号, pp. 305-317, SEP 9 2013
  5. Acquired Deficiency of A20 Results in Rapid Apoptosis, Systemic Inflammation, and Abnormal Hematopoietic Stem Cell Function, PLOS ONE, 9巻, 1号, JAN 31 2014
  6. SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS, LEUKEMIA, 29巻, 4号, pp. 847-857, APR 2015
  7. -7/7q-syndrome in myeloid-lineage hematopoietic malignancies: attempts to understand this complex disease entity, ONCOGENE, 34巻, 19号, pp. 2413-2425, MAY 7 2015
  8. Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2, BLOOD, 125巻, 22号, pp. 3437-3446, MAY 28 2015
  9. Involvement of resistin-like molecule beta in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice, SCIENTIFIC REPORTS, 6巻, JAN 28 2016
  10. Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency, SCIENTIFIC REPORTS, 6巻, JUL 19 2016
  11. Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia, EXPERIMENTAL HEMATOLOGY, 44巻, 8号, pp. 745-754, AUG 2016
  12. Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113巻, 37号, pp. 10370-10375, SEP 13 2016
  13. Identification of cooperative genes for E2A-PBX1 to develop acute lymphoblastic leukemia., CANCER SCIENCE, 107巻, 7号, pp. 890-898, JUL 2016
  14. Acquired expression of Cbl(Q367P) in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia, BLOOD, 129巻, 15号, pp. 2148-2160, APR 13 2017
  15. A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection, PLOS PATHOGENS, 14巻, 2号, FEB 2018