藤本 成明Nariaki Fujimoto

Last Updated :2020/05/22

所属・職名
原爆放射線医科学研究所 放射線障害機構研究部門 准教授
メールアドレス
nfjmhiroshima-u.ac.jp

基本情報

学位

  • 博士(医学) (広島大学)
  • 学術修士 (広島大学)

研究分野

  • 環境学 / 環境解析学 / 放射線・化学物質影響科学
  • 医歯薬学 / 外科系臨床医学 / 泌尿器科学
  • 生物学 / 生物科学 / 機能生物化学

研究キーワード

  • 腫瘍増殖|前立腺癌
  • 再生|甲状腺ホルモン
  • 視床下部下垂体甲状腺系
  • エストロゲン
  • 下垂体
  • 甲状腺腫瘍
  • 内分泌攪乱物質
  • 低用量効果
  • エストロゲン

所属学会

  • 日本内分泌学会
  • ヨーロッパ内分泌学会
  • 日本ステロイドホルモン学会
  • 日本毒性病理学会
  • 環境ホルモン学会

研究活動

学術論文(★は代表的な論文)

  1. Study of metablic activation of the UV-filter octyl methoxycinnamate for endocrine-disrupting activity, Fundamental Toxicological Sciences, 5巻, 6号, pp. 185-193, 20181218
  2. Identification of hepatic thyroid hormone-responsive genes in neonatal rats: Potential targets for thyroid hormone-disrupting chemicals, TOXICOLOGY LETTERS, 286巻, pp. 48-53, 201804
  3. 56MnO2粉塵暴露によるラットの活動量への影響, 広島医学, 71巻, 4号, pp. 373-376, 201804
  4. Altered expression of the Olr59, Ethe1, and Slc10a2 genes in the liver of F344 rats by neonatal thyroid hormone disruption, JOURNAL OF APPLIED TOXICOLOGY, 37巻, 9号, pp. 1030-1035, 201709
  5. Internal exposure to neutron-activated Mn-56 dioxide powder in Wistar rats: part 1: dosimetry, RADIATION AND ENVIRONMENTAL BIOPHYSICS, 56巻, 1号, pp. 47-54, 201703
  6. Internal exposure to neutron-activated Mn-56 dioxide powder in Wistar rats-Part 2: pathological effects, RADIATION AND ENVIRONMENTAL BIOPHYSICS, 56巻, 1号, pp. 55-61, 201703
  7. Increase in prostate stem cell antigen expression in prostatic hyperplasia induced by testosterone and 17 beta-estradiol in C57BL mice, JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 158巻, pp. 56-62, 201604
  8. In vitro metabolism of methiocarb and carbaryl in rats, and its effect on their estrogenic and antiandrogenic activities, ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 41巻, pp. 289-297, 201601
  9. Irradiation of laboratory animals by neutron activated dust: development and application of the method - first results of international multicenter study, Radiation and Risk, 25巻, 4号, pp. 111-125, 2016
  10. Changes in plasma triiodothyronine, thyroxine, and thyroid-stimulating hormone after 131I irradiation of newborn rats fed with iodine deficient diet, Science and Health, 2016-3巻, pp. 26-33, 2016
  11. In vitro metabolism of cis- and trans-permethrin by rat liver microsomes, and its effect on estrogenic and anti-androgenic activities, ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 37巻, 3号, pp. 996-1005, 201405
  12. ★, Cell type-dependent agonist/antagonist activities of polybrominated diphenyl ethers, TOXICOLOGY LETTERS, 223巻, 2号, pp. 192-197, 20131125
  13. Neonatal exposure to 2,337,8-tetrachlorodibenze-p-dioxin increases the mRNA expression of prostatic proteins in C57BL mice, JOURNAL OF TOXICOLOGICAL SCIENCES, 38巻, 2号, pp. 279-283, 201304
  14. Estrogen and androgen receptor status in hepatocellular hypertrophy induced by phenobarbital, clofibrate, and piperonyl butoxide in F344 rats, JOURNAL OF TOXICOLOGICAL SCIENCES, 37巻, 2号, pp. 281-286, 201204
  15. ★, An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide, TOXICOLOGY LETTERS, 208巻, 1号, pp. 30-35, 20120105
  16. ★, Androgen dependent transcription of a mouse prostatic protein gene, PSP94: involvement of estrogen receptors, The Journal of Steroid Bio-chemistry and Molecular Biology, 127巻, pp. 301-306, 20111101
  17. ★, Identification of rat prostatic secreted proteins using mass spectrometric analysis and androgen-dependent mRNA expression, Journal of Andrology, 30巻, pp. 669, 20091101
  18. Affinity for Thyroid Hormone and Estrogen Receptors of Hydroxylated Polybrominated Diphenyl Ethers, Journal of Health Science, 54巻, pp. 607, 20081001
  19. Metabolic activation of proestrogens in the environment by cytochrome P450 system., J. Health Sci., 54巻, 5号, pp. 343-355, 20080501
  20. Effects of environmental antiandrogenic chemicals on expression of androgen-responsive genes in rat prostate lobes., J. Health Sci., 53巻, pp. 401-405, 20070625
  21. ★, In vivo function of the 5’ flanking region of mouse estrogen receptor beta gene., J. Steroid Biochem. Mol. Biol., 105巻, 1-5号, pp. 57-62, 20070601
  22. Quantative determination of lobe specificity of mRNA expression of androgen-dependent genes in the rat prostate gland., Endcrinol. J., 54巻, 1号, pp. 123-132, 20070405
  23. PSPC1, NONO, and SFPQ are expressed in mouse Sertoli cells and may function as coregulators of androgen receptor-mediated transcription., Biol Reprod, 75巻, 3号, pp. 352-359, 20060901
  24. Identification of prostatic-secreted proteins in mice by mass spectrometric analysis and evaluation of lobe-specific and androgen-dependent mRNA expression, JOURNAL OF ENDOCRINOLOGY, 190巻, 3号, pp. 793-803, 200609
  25. Metabolism of the alpha,beta-unsaturated ketones, chalcone and trans-4-phenyl-3-buten-2-one, by rat liver microsomes and estrogenic activity of the metabolites, DRUG METABOLISM AND DISPOSITION, 33巻, 8号, pp. 1115-1123, 200508
  26. Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds, TOXICOLOGICAL SCIENCES, 84巻, 2号, pp. 249-259, 200504
  27. Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture, TOXICOLOGY, 208巻, 3号, pp. 377-387, 20050330
  28. Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis, LIFE SCIENCES, 76巻, 14号, pp. 1589-1601, 20050218
  29. Estrogenic and antiandrogenic activities of 17 benzophenone derivatives used as UV stabilizers and sunscreens, TOXICOLOGY AND APPLIED PHARMACOLOGY, 203巻, 1号, pp. 9-17, 20050215
  30. ★, Cloning and characterization of the 5 '-flanking region of the rat estrogen receptor beta gene, JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 94巻, 1-3号, pp. 15-21, 200502
  31. Estrogen enhancement of androgen-responsive gene expression in hormone-induced hyperplasia in the ventral prostate of F344 rats, CANCER SCIENCE, 95巻, 9号, pp. 711-715, 200409
  32. Identification of estrogen-responsive genes in the GH3 cell line by cDNA microarray analysis, JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 91巻, 3号, pp. 121-129, 200407
  33. Activation of estrogen response element dependent transcription by thyroid hormone with increase in estrogen receptor levels in a rat pituitary cell line, GH3, JOURNAL OF ENDOCRINOLOGY, 181巻, 1号, pp. 77-83, 200404
  34. Potent estrogenic metabolites of bisphenol A and bisphenol B formed by rat liver S9 fraction: Their structures and estrogenic potency, TOXICOLOGICAL SCIENCES, 78巻, 1号, pp. 50-59, 200403
  35. Estrogenic activity of an antioxidant, nordihydroguaiaretic acid (NDGA), LIFE SCIENCES, 74巻, 11号, pp. 1417-1425, 20040130
  36. Effects of environmental estrogenic chemicals on AP1 mediated transcription with estrogen receptors alpha and beta, JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 88巻, 1号, pp. 53-59, 200401
  37. Effects of environmental estrogenic compounds on growth of a transplanted estrogen responsive pituitary tumor cell line in rats, Food Chem. Toxicol. , 41巻, 12号, pp. 1711-1717, 200312
  38. Estrogenic activity of stilbene derivatives, J. Health Sci., 49巻, 5号, pp. 359-367, 200310
  39. Metabolic activation of proestrogenic diphenyl and related compounds by rat liver microsomes, J. Health Sci., 49巻, 4号, pp. 298-310, 200308
  40. Estrogenic activity of an environmental pollutant, 2-nitrofluorene, after metabolic activation by rat liver microsomes, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 303巻, 2号, pp. 419-426, 20030404
  41. ★, Estrogenic Activity of Styrene Oligomers after Metabolic Activation by Rat Liver Microsomes, Env. Health Persp, 111巻, 3号, pp. 329-334, 20030401
  42. Regulation of Estrogen Receptor αand βExpression by Testosterone in the Rat Prostate Gland, Endocrine Journal, 50巻, 3号, pp. 281-287, 20030401
  43. Antiandrogenic activity and metabolism of the organophosphorus pesticide fenthion and related compounds, Env. Health Persp, 111巻, 4号, pp. 503-508, 200304
  44. Tumorigenesis in infant C3H/HeN mice exposed to tritiated water (HTO), J. Radiation Res., 43巻, 4号, pp. 345-351, 200212
  45. Iron lactate induction of pancreatic and endometrial proliferative lesions and a lack of increased tumors in a 104-week carcinogenicity study in F344 rats, Food Chem. Toxicol. , 40巻, 10号, pp. 1441-1448, 200210
  46. Thyroid hormonal activity of the flame retardants tetrabromobisphenol A and tetrachlorobisphenol, Biochem. Biophys. Res. Commun., 239巻, pp. 554-559, 20020401
  47. 放射線の内分泌影響, 放射線生物研究, 37巻, pp. 243-250, 20020401
  48. Tumorigenesis in infant C3H/HeN mice exposed to tritiated water (HTO), J. Radiat. Res., 43巻, pp. 345-351, 20020401
  49. Age-dependent exposure to radioactive iodine (I-131) in the thyroid and total body of newborn, pubertal and adult Fischer 344 rats, J. Radiation Res., 42巻, 2号, pp. 143-155, 200106
  50. Dose-threshold for thyroid tumor-promoting effects of orally administered kojic acid in rats after initiation with N-bis(2-hydroxypropyl) nitrosamine., J Toxicol Sci., 26巻, 2号, pp. 85-94, 20010401
  51. Effects of endocrine disruptors on the pituitary gland., J. Toxicol. Pathol., 14巻, pp. 65-69, 20010401
  52. Strain Difference in Regulation of Pituitary Tumor Transforming Gene (PTTG) in Estrogen Induced Pituitary Tumorigenesis in Rats, Jpn.J.Cancer Res., 92巻, 10号, pp. 1034-1040, 20010401
  53. Supression by estrogen receptor β of AP-1 mediated transactivation through estrogen receptor α., J. Steroid Biochem. Mol. Biol., 78巻, 7-8号, pp. 177-184, 20010401
  54. Sex hormone dependency of diethylnitrosamine-induced liver tumors in mice and chemoprevention by leuprorelin, Jpn.J.Cancer Res., 92巻, 3号, pp. 249-256, 200103
  55. 252CfおよびDEN誘発マウス肝腫瘍における抗アンドロゲン療法の検討, 広島医学, 53巻, 3号, pp. 175-177, 20000401
  56. Expression of estrogen receptor α and βmRNAs in prostate cancers treated with leuprorelin acetate, Euro.Urol., 38巻, pp. 635-639, 20000401
  57. ラットの下垂体のエストロゲン受容体調節における2種のプロモータの関与について., ホルモンと臨床, 48巻, 増刊号号, pp. 102-105, 20000401
  58. 131I内部被ばくによる甲状腺発がんモデルの開発, 放射線科学, 42巻, 6号, pp. 141-144, 19990401
  59. Establishment of an estrogen responsive rat pituitary cell sub-line MtT/E-2, Endocrine J., 46巻, pp. 389-396, 19990401
  60. Gastric tumor induction by 1,2-dimethylhydrazine in Wistar rats with intestinal metaplasia caused by X-irradiation., Jpn.J.Cancer Res., 90巻, pp. 1207-1211, 19990401
  61. Growth stimulation of a rat pituitary cell line MtT/E-2 by environmental estrogens in vitro and in vivo, Endocrine J., 46巻, pp. 531-538, 19990401
  62. Influence of concomitant miso or NaCl treatment on induction of gastric tumors by N-methyl-N’-nitro-N-nitrosoguanidine in rats., Oncol.Rep., 6巻, 5号, pp. 989-993, 19990401
  63. Inhibition of thyroid iodine uptake and organification in rats treated with kojic acid., Toxicol. Sci., 47巻, pp. 170-175, 19990401
  64. Induction of ovarian tumors by heavy ion irradiation in B6C3F1 mice., Oncol.Rep., 5巻, pp. 1377-1380, 19980401
  65. Induction of thyroid tumours in(C57BL/6NxC3H/N)F1 mice by oral administration of kojicacid, Food Chem. Toxicol. , 36巻, pp. 697-703, 19980401
  66. No susceptibility of colon tissue implanted into the glandular stomach of rats to N-nitroso-N-methylurea carcinogenesis., Oncol.Rep., 5巻, 6号, pp. 1373-1376, 19980401
  67. Oral administration of tritiated water (HTO) in mouse. III: Low dose-rate irradiation and threshold dose-rate for radiation risk., Int J Radiat Biol, 73巻, pp. 535-541, 19980401
  68. 低ヨード食投与ラットでの^131^I投与後の血中T3、TSHの変化-加齢による差異の検討-, 広島医学, 51巻, pp. 376-379, 19980401
  69. 放射線による甲状腺癌誘発機構の解析.I131を内部照射したラット甲状腺および全身の吸収線量推計とその年齢依存性, 広島医学, 51巻, pp. 379-384, 19980401
  70. Up-regulation of the estrogen receptor by triiodothyronine in rats pituitary cell line., J. Steroid Biochem. Molec. Biol., 61巻, pp. 79-85, 19970401
  71. ラットに N-methyl-N’-nitro-N-nitrosoguanidine (MNNG) 投与中に与えた味噌餌の胃腫瘍抑制効果。, 味噌の科学と技術, 45巻, pp. 107-115, 19970401
  72. Up-regulation on the estrogen receptor by triiodothyronine in rat pituitary cell lines, J. Steroid Biochem. Molec. Biol., 61巻, pp. 79-85, 19970401
  73. Blockade of the estrogen induced increase in progesterone receptor caused by propylthiouracil, an anti-thyroid drug, in a transplantable pituitary tumor in rats., Endocrine J., 43巻, pp. 329-334, 19960401
  74. Enhancing effects of immunization with rectal extract on rectal carcinogenesis by local X-irradiation caused in male A/HeJ mice., Onco. Rep., 3巻, pp. 707-712, 19960401
  75. Gastric tumorigenicity of 1,2-dimethylhydrazine on the background of gastric intestinal metaplasia induced by X-irradiation in CD(SD) rats., Jpn.J.Cancer Res., 87巻, pp. 433-436, 19960401
  76. Influence of paternal 252-Cf neutron exposure on abnormal sperms, embryonal lethality, and liver tumorigenesis in the F1 offsprings of mice., Jpn.J.Cancer Res., 87巻, pp. 51-57, 19960401
  77. Promotion of thyroid tumors in F344 male rats given a low iodine diet after treatment with N-methyl-N-nitrosourea in their drinking water., J. Toxico. Pathol., 9巻, pp. 191-197, 19960401
  78. Antiestrogens: Mechanisms and actions in target cells., J. Steroid Biochem. Molec. Biol., 53巻, pp. 387-393, 19950401
  79. Elevated serum growth hormone accelerates gastric tumorigenesis in F344 rats after treatment with N-methyl-N-nitrosourea in their drinking water., Jpn.J.Cancer Res., 86巻, pp. 631-637, 19950401
  80. Estrogen and carcinogenesis, J. Toxic. Path., 8巻, pp. 285-289, 19950401
  81. Progesterone enhancement of stomach tumor development in CD rats treated with N-methyl-N’-nitro-N-nitrosoguanidine., Jpn.J.Cancer Res., 86巻, pp. 924-928, 19950401
  82. Alteration in the agonist/antagonist balance of antiestrogens by activation of protein kinase A signaling pathways in breast cancer cells : Antiestrogen selectivity and promoter dependence, Molecular Endocrinology, 8巻, pp. 296-304, 19940401
  83. Chronic toxicity study of Gardenia yellow color in C57BL mice., J. Toxic. Path., 7巻, pp. 455-460, 19940401
  84. Inhibition of mammary tumors by pretreatment with 17beta-estradiol in F344 rats induced with N-methyl-N-nitrosourea., Jpn.J.Cancer Res., 84巻, pp. 279-283, 19940401
  85. Tumorigenicity study of phloxine (FR 104) in B63F1 mice., Fd Chem. Toxic., 32巻, pp. 517-520, 19930401
  86. Increase in estrogen receptor levels in MNV-induced thyroid tumors in LE rats, Carcinogenesis, 13巻, 8号, pp. 1315-1318, 19920401
  87. 胃癌誘発に及ぼすプロラクチンの影響, 広島医学, 5巻, pp. 93-97, 19920401
  88. Direct up-regulation of estrogen receptor by triiodothyronine in rat pituitary tumor M+T/F84,, Endocrinologica Japonica, 38巻, 4号, pp. 405-412, 19910401
  89. Estrogen dependent growth of a rat pituitary tumor (MtT/F84), Chem. Carcinogenesis, 2巻, pp. 264-270, 19910401
  90. Estrogen receptor levels and tumor growth in a series of pituitary clonal cell lines in rats., Jpn.J.Cancer Res., 82巻, pp. 1436-1441, 19910401
  91. Photodynamic therapy for rat pituitary tumor in vitro and in vivo using pheophorbide-a and white light, Lasers Surg., 11巻, pp. 174-182, 19910401
  92. Stimulatory effects of retinoic acid on tumor growth and serum insulin-like growth factor-1 in rats bearing estrogen responsive pituitary tumor MtT/Se., Jpn.J.Cancer Res., 82巻, pp. 815-819, 19910401
  93. Establishment of a series of pituitary clonal cell lines differing in morphology, hormone secretion, and response to estrogen., Endocrinology, 126巻, pp. 2313-2320, 19900401
  94. Growth promoting effect of retinoic acid in transplantable pituitary tumor of rat., Jpn.J.Cancer Res., 81巻, pp. 878-883, 19900401
  95. Promoting action of prolactin released from a grafted transplantable pituitary tumor (MtT/F84) on rat prostate carcinogenesis., Cancer Letters, 53巻, pp. 151-157, 19900401
  96. Effects of sex difference, gonadectomy and estradiol on N-ethyl-N- nitrosourea-induced trigeminal nerve tumors in rats, Carcinogenesis, 10巻, pp. 1505-1509, 19890401
  97. Increase of estrogen receptor level by thyroxin in estrogen dependent pituitary tumor (MtT/F84) in rats., Biochem. Biophys. Res. Comm., 152巻, pp. 44-48, 19880401
  98. Inhibition by 2-bromo-alpha-ergocriptine on the proliferation of an mono-dispersed MtT/F84 cells inoculated in 17beta-estradiol treated rats., Proc. Hiroshima Univ. RINMB ll : l52-l65= l970., 28巻, pp. 211-217, 19870401
  99. Induction of thyroid tumors in (C57BL/6NxC3H/N)F1 mice by oral administration of 9-3’, 4’, 5’, 6’-tetrachloro-o-carboxy phenyl-6-hydroxy-2,4,5,7-tetraiodo-3-isoxanthone sodium (food red 105, Rose Bengal B), JNCI, 77巻, pp. 277-281, 19860401
  100. X線照射により生じた動脈炎, 広島医学, 39巻, pp. 428-430, 19860401
  101. 放射線誘発乳腺腫瘍のestrogen(E2)、系統差にによる修飾について, 広島医学, 39巻, pp. 425-427, 19860401
  102. Inhibition by 2-bromo-alpha-ergocriptine and tamoxifen of the growth of an estrogen-dependent transplantable pituitary tumor(MtT/F84) in F344 rats., Cancer Res., 45巻, pp. 6436-6441, 19850401
  103. Amino acid sequence of a ferredoxin from thermoacidophilic archaebacteria, Thermoplasma acidophulum., FEBS Letters, 162巻, pp. 21-24, 19830401

招待講演、口頭・ポスター発表等

  1. Effects of exposure to radioactive 56MnO2 powder on the gene expression in the lung and the liver of rats, Fujimoto N, Kairkhanova Y, Saimova A, Uzbekov D, Chaizhunusova N, Shichijo K, Nakashima M, Rakhypbekov T, Hoshi M, The 21st Hiroshima International Symposium, 2018年01月28日, 招待, 英語, HISOC, Hiroshima University, Hiroshima
  2. Effects of exposure to radioactive 56MnO2 powder on the gene expression of liver in rats, Nariaki Fujmoto, Ynkar Kairkhanova, Aisulu Saimova, Darkhan Uzbekov, Nailya Chaizhunusova, Kazuko Shichijo, Masahiro Nakashima, Tolebay Rakhypbekov, Masaharu Hoshi, The 5th Shimane Semey International Symposium, 2018年01月25日, 招待, 英語, Shiname University, Izumo, Shimane
  3. 新生仔ラット甲状腺の電離放射線への感受性, 藤本成明、松山睦美、中島正洋, 第59回原子爆弾後障害研究会, 2018年06月03日, 通常, 日本語, 長崎原子爆弾後障害研究会, 長崎
  4. Internal exposure to radioactive 56Mn dioxide powder in rats - Effects on gene expressions, Nariaki Fujimoto, Ynkar Kairkhanova, Aisulu Saimova, Darkhan Uzbekov, Nailya Chaizhunusova, Kazuko Shichijo, Masahiro Nakashima, Tolebay Rakhypbekov, Valeriy Stepanenko, Masaharu Hoshi, The XIII International Research and Practical conference "Ecology. Health. Radiation", 2017年08月29日, 招待, 英語, Semey State Medical University, Kazakhstan, Semey State Medical University, Kazakhstan
  5. Changes in radiation injury related mRNA expression in the lung of rats exposed to radioactive 56MnO2 powder, Nariaki FUJIMOTO, Ynkar Kairkhanova, Aisulu Saimova, Darkhan Uzbekov, Nailya Chaizhunusova, Kazuko Shichijo, Masahiro Nakashima, Tolebay Rakhypbekov, Masaharu Hoshi, The 4th Shimane-Semey International Symposium, 2017年01月26日, 招待, 英語, Shimane University, Izumo, Shimane
  6. Changes in lung injury related mRNA expression in rats exposed to neutron-activated 56Mn powder, 藤本成明, Ynkar Kairkhanova, Aisulu Saimova, Darkhan Uzbekov, Nailya Chaizhunusova, Masahiro Nakashima, Tolebay Rakhypbekov, Masaharu Hoshi, ワークショップ 56Mnの内部被ばく実験とその結果 -微粒子効果の可能性について-, 2016年12月09日, 招待, 日本語, 広島大学・平和研究センター, 広島
  7. Hepatic Thyroid Hormone Responsive Genes in Rat Neonates - Potential Targets for Thyroid Hormone Disrupting Chemicals, Nariaki Fujimoto, Shinichi Miyagawa, Taisen Iguchi, NIBB conference, Environment to Bioresponse., 通常, 英語, 基礎生物学研究所, 岡崎市
  8. Mn-56内部被爆ラットにおける肺の放射線障害と関連遺伝子発現への影響, 藤本 成明,, Kairkhanova Ynkar, Saimova Aisulu, Uzbekov Darkhan, Chaizhunusova Nailya, 七條 和子, 中島 正洋 , Rakhypbekov Tolebay , 星 正治, 第39回日本分子生物学会年会, 2016年11月30日, 通常, 英語, 日本分子生物学会, 横浜
  9. テストステロンとエストラジオールで誘発されたマウス前立腺肥大のPSCA (Prostate Stem Cell Antigen)発現, 藤本成明, 菅野純, 第23回日本ステロイドホルモン学会, 2016年01月15日, 通常, 日本語, 日本ステロイドホルモン学会, 倉敷市
  10. アンドロゲン誘導性マウス前立腺肥大におけるエストロゲンの相乗作用, 藤本成明, 菅野純, 第88回日本内分泌学会学術総会, 2015年04月24日, 通常, 日本語, 日本内分泌学会, 東京
  11. 新生仔ラットへの水酸化PBDE投与の影響, 藤本成明, 中村直樹, 佐能正剛,太田茂,浦丸直人,北村繁幸, 宮川信一, 井口泰泉, , 環境ホルモン学会第17回研究発表会, 2014年12月09日, 通常, 日本語, 日本環境ホルモン学会, 東京
  12. Thyroid hormone activity of PBDEs in vitro and in vivo, Fujimoto, N., Nakamura, N., Sanoh, S., Ohta, S., Kitamura, S, 15th Asia Oceania Congress of Endocrinology, 2014年10月10日, 通常, 英語, Philippine Society of Endocrinology and Metabolism, Cebu, Philippines
  13. マウス前立腺分泌タンパク質の同定とそのアンドロゲン応答性転写, 藤本 成明, 前立腺生物学シンポジウム2006, 2006年07月, 招待, 日本語
  14. In vivo functional analysis of the estrogen receptor beta gene promoter, 藤本 成明, 13th Asia-Oceania Congress of Endocrinology, 2006年05月, 招待, 日本語
  15. 下垂体:内分泌かく乱化学物質の発癌修飾作用, 藤本 成明, 日本毒性病理学会, 2000年01月, 招待, 日本語
  16. 内分泌かく乱化学物質の作用メカニズム, 藤本 成明, 日本食品化学会, 1998年07月, 招待, 日本語
  17. 新生仔期での甲状腺被曝で特異的に誘発される甲状腺病変, 藤本成明、松山睦美、中島正洋, 第35回日本毒性病理学会総会学術集会, 2019年01月31日, 通常, 日本語
  18. ラット新生仔期甲状腺への放射線被曝で誘発される甲状腺機能不全, 藤本成明、松山睦美、中島正洋, 第92回日本内分泌学会学術総会, 2019年05月10日, 通常, 日本語
  19. Pathology and gene expression changes in the lung of rats exposed to 56MnO2 powders, Fujimoto,N, The 22nd Hiroshima International Symposium International Research Meeting for Studies of Biological Effects of Radioactive Microparticles in Kazakh, Russia & Japan, 2019年02月28日, 招待, 英語

受賞

  1. 2003年, 最優秀論文賞
  2. 2013年, 最優秀ポスター賞

社会活動

委員会等委員歴

  1. 食品安全委員会専門委員, 2005年04月, 2016年03月, 内閣府食品安全委員会
  2. 食品安全委員会農薬専門調査会参考人, 2016年04月, 2018年03月, 内閣府食品安全委員会
  3. 食品安全委員会専門委員, 2018年04月, 2020年03月, 内閣府食品安全委員会

学術雑誌論文査読歴

  1. 2018年, General and Comparative Endocrinology, その他, Reviewer, 1