藤村 孝志TAKASHI FUJIMURA

Last Updated :2019/10/01

所属・職名
大学院統合生命科学研究科先端・分子生命化学(先端支援室)特任助教
メールアドレス
fmuratkshiroshima-u.ac.jp

研究活動

学術論文(★は代表的な論文)

  1. Impact of Histone H1 on the Progression of Allergic Rhinitis and Its Suppression by Neutralizing Antibody in Mice, PLOS ONE, 11巻, 4号, 2016
  2. A novel methoxyflavanone from a Chinese medicinal herb (Perilla frutescens) induces G2/M cell cycle arrest and apoptosis in A549 human lung adenocarcinoma cells, CANCER RESEARCH, 76巻, 2016
  3. Increase of regulatory T cells and the ratio of specific IgE to total IgE are candidates for response monitoring or prognostic biomarkers in 2-year sublingual immunotherapy (SLIT) for Japanese cedar pollinosis, CLINICAL IMMUNOLOGY, 139巻, 1号, pp. 65-74, 2011
  4. Approaches to immunotherapies for Japanese cedar pollinosis, AURIS NASUS LARYNX, 38巻, 4号, pp. 431-438, 2011
  5. Immunological parameters associated with the development of allergic rhinitis: A preliminary prospective study, AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 26巻, 2号, pp. 92-96, 2012
  6. A randomized controlled trial of sublingual immunotherapy for Japanese cedar pollinosis, INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 146巻, 1号, pp. 76-84, 2008
  7. Exposure to positively- and negatively-charged plasma cluster ions impairs IgE-binding capacity of indoor cat and fungal allergens, WORLD ALLERGY ORGANIZATION JOURNAL, 9巻, 2016
  8. Prominent IgE-binding and cytokine-inducing capacities of a newly cloned N-terminal region of Der f 14, an apolipophorin-like house dust mite allergen, JOURNAL OF BIOCHEMISTRY, 163巻, 1号, pp. 51-60, 2018
  9. A methoxyflavanone derivative from the Asian medicinal herb (Perilla frutescens) induces p53-mediated G(2)/M cell cycle arrest and apoptosis in A549 human lung adenocarcinoma, CYTOTECHNOLOGY, 70巻, 3号, pp. 899-912, 2018
  10. Synergistic tumor suppression by a Perilla frutescens-derived methoxyflavanone and anti-cancer tyrosine kinase inhibitors in A549 human lung adenocarcinoma, CYTOTECHNOLOGY, 70巻, 3号, pp. 913-919, 2018
  11. Anti-inflammatory intravenous immunoglobulin (IVIg) suppresses homeostatic proliferation of B cells, CYTOTECHNOLOGY, 70巻, 3号, pp. 921-927, 2018
  12. Der f 34, a Novel Major House Dust Mite Allergen Belonging to a Highly Conserved Rid/YjgF/YER057c/UK114 Family of Imine Deaminases, JOURNAL OF BIOLOGICAL CHEMISTRY, 291巻, 41号, pp. 21607-21615, 2016
  13. A flavanone derivative from the Asian medicinal herb (Perilla frutescens) potently suppresses IgE-mediated immediate hypersensitivity reactions, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 483巻, 1号, pp. 674-679, 2017
  14. Plasma Cluster Ions Reduce the IgE-Binding Capacity of House Dust Mite Allergens under a Simulated Indoor Environmental Condition, INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 173巻, 4号, pp. 199-203, 2017
  15. Der f 35: An MD-2-like house dust mite allergen that cross-reacts with Der f 2 and Pso o 2, ALLERGY, 72巻, 11号, pp. 1728-1736, 2017
  16. The Induced Regulatory T Cell Level, Defined as the Proportion of IL-10(+)Foxp3(+) Cells among CD25(+)CD4(+) Leukocytes, Is a Potential Therapeutic Biomarker for Sublingual Immunotherapy: A Preliminary Report, INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 153巻, 4号, pp. 378-387, 2010
  17. Induction of Th1 immune responses to Japanese cedar pollen allergen (Cry j 1) in mice immunized with Cry j 1 conjugated with CpG oligodeoxynucleotide, COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, 34巻, 2号, pp. 157-161, 2011
  18. IgE reactivity to a Cry j 3, an allergen of Japanese cedar (Cryptomeria japonica) pollen in dogs with canine atopic dermatitis, VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 149巻, 1-2号, pp. 132-135, 2012
  19. Recombinant Fusion Allergens, Cry j 1 and Cry j 2 from Japanese Cedar Pollen, Conjugated with Polyethylene Glycol Potentiate the Attenuation of Cry j 1-Specific IgE Production in Cry j 1-Sensitized Mice and Japanese Cedar Pollen Allergen-Sensitized Monkeys, INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 168巻, 1号, pp. 32-43, 2015