Last Updated :2020/12/01

Affiliations, Positions
Hiroshima University Hospital, Associate Professor or Lecturer

Basic Information

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Urology

Research Keywords

  • Erectile dysfunction Laparoscopic surgery QOL analysis of minimally invasive surgery Tissue engineering of urogenital organs

Affiliated Academic Societies

  • Japanese Urological Association The Japanese Society for Sexual Medicine Japan Society of Reproductive Endocrinology The Japanese Association of Men’s Health Japanese Society of Endourology(Councilor) Japan Society for Endoscopic Surgery Japan Robotic Surgery Society Japan Association of Endocrine Surgeons Japan Society of Urologic Oncology International Society for Sexual Medicine (ISSM)

Educational Activity

Course in Charge

  1. 2020, Undergraduate Education, Year, Clinical diagnosis and treatment II

Research Activities

Academic Papers

  1. Retrospective analysis of the distance between the neurovascular bundle and prostate cancer foci in radical prostatectomy specimens: its clinical implication in nerve-sparing surgery., BJU INTERNATIONAL, 104(8), 1085-1090, OCT 2009
  2. ★, Five-year longitudinal effect of radical perineal prostatectomy on health-related quality of life in Japanese men, using general and disease-specific measures., BJU INTERNATIONAL, 104(8), 1077-1084, OCT 2009
  3. ★, Impact of a novel, extended approach of perineal radical prostatectomy on surgical margins in localized prostate cancer., BJU INTERNATIONAL, 106(1), 44-48
  4. Identification of lymphatic pathway involved in the spreading of prostate cancer by fluorescence navigation approach with intraoperatively injected indocyanine green, CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL, 5(4), 254-259, AUG 2011
  5. Comparison of Renal Function after Partial Nephrectomy and Radical Nephrectomy for Renal Cell Carcinoma, UROLOGIA INTERNATIONALIS, 89(2), 227-232, 2012
  6. Impact of pre-implant lower urinary tract symptoms on postoperative urinary morbidity after permanent prostate brachytherapy, INTERNATIONAL JOURNAL OF UROLOGY, 19(12), 1083-1089, DEC 2012
  7. Impact of Laparoscopic Experience on the Proficiency Gain of Urologic Surgeons in Robot-Assisted Surgery, JOURNAL OF ENDOUROLOGY, 26(12), 1635-1638, DEC 2012
  8. Identification of lymphatic pathway involved in the spread of bladder cancer: Evidence obtained from fluorescence navigation with intraoperatively injected indocyanine green, CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL, 7(5-6), E322-E328, 20120901
  9. Paget's disease of the vulva with bladder invasion: a case report., Arch Gynecol Obstet., 285(5), 1493-6, 20120501
  10. Therapeutic efficacy of narrow band imaging-assisted transurethral electrocoagulation for ulcer-type interstitial cystitis/painful bladder syndrome, INTERNATIONAL JOURNAL OF UROLOGY, 21, 57-60, APR 2014
  11. Rat Cavernous Nerve Reconstruction with CD133(+) Cells Derived from Human Bone Marrow, JOURNAL OF SEXUAL MEDICINE, 11(5), 1148-1158, MAY 2014
  12. Prognostic significance of C-reactive protein in patients with intermediate-risk metastatic renal cell carcinoma treated with molecular targeted therapy, ONCOLOGY LETTERS, 8(2), 881-885, AUG 2014
  13. Patient-reported satisfaction and cosmesis outcomes following laparoscopic adrenalectomy: Laparoendoscopic single-site adrenalectomy vs. conventional laparoscopic adrenalectomy, CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL, 8(1-2), E20-E25, JAN 2014
  14. Laparoendoscopic Single-Site Adrenalectomy sans Transumbilical Approach: Initial Experience in Japan, UROLOGY JOURNAL, 11(4), 1772-1776, JUL-AUG 2014
  15. Retention of robot-assisted surgical skills in urological surgeons acquired using Mimic dV-Trainer, CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL, 8(7-8), E493-E497, JUL 2014
  16. Population perception of surgical approach in minimally invasive surgery, CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL, 9(1-2), E1-E4, JAN 2015
  17. FGF19 Promotes Progression of Prostate Cancer, PROSTATE, 75(10), 1092-1101, JUL 1 2015
  18. Needlescopic-assisted laparoendoscopic single-site adrenalectomy, ASIAN JOURNAL OF SURGERY, 39(1), 6-11, JAN 2016
  19. The impact of change in serum C-reactive protein level on the prediction of effects of molecular targeted therapy in patients with metastatic renal cell carcinoma, BJU INTERNATIONAL, 117(6B), E67-E74, JUN 2016
  20. Effect of Spatial Cognitive Ability on Gain in Robot-Assisted Surgical Skills of Urological Surgeons, JOURNAL OF SURGICAL EDUCATION, 73(4), 624-630, JUL-AUG 2016
  21. Reply. Needlescopic-assisted laparoendoscopic single-site adrenalectomy., ASIAN JOURNAL OF SURGERY, 39(2), 123-123
  22. Laparoendoscopic single-site surgeries: A multicenter experience of 469 cases in Japan, INTERNATIONAL JOURNAL OF UROLOGY, 24(1), 69-74, JAN 2017
  23. Regeneration of rat corpora cavernosa tissue by transplantation of CD133(+) cells derived from human bone marrow and placement of biodegradable gel sponge sheet, ASIAN JOURNAL OF ANDROLOGY, 19(2), 203-207, MAR-APR 2017
  24. Impact of neutrophil-to-lymphocyte ratio on effects of targeted therapy for metastatic renal cell carcinoma patients with extrapulmonary metastasis, CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL, 11(5), E207-E214, MAY 2017
  25. Combination therapy using molecular-targeted drugs modulates tumor microenvironment and impairs tumor growth in renal cell carcinoma, CANCER MEDICINE, 6(10), 2308-2320, OCT 2017
  26. Enzalutamide versus abiraterone as a first-line endocrine therapy for castration-resistant prostate cancer (ENABLE study for PCa): a study protocol for a multicenter randomized phase III trial, BMC CANCER, 17, OCT 10 2017
  27. Serous adenocarcinoma of retroperitoneum: a case report, INTERNATIONAL CANCER CONFERENCE JOURNAL, 6(4), 154-157, OCT 2017
  28. The effect of kinetics of C-reactive protein in the prediction of overall survival in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitor, UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 35(11), NOV 2017
  29. Low-intensity extracorporeal shock wave therapy for patients with severe erectile dysfunction due to radical prostatectomy., Ann Res Hosp, 1(2)
  30. Usefulness of personalized three-dimensional printed model on the satisfaction of preoperative education for patients undergoing robot-assisted partial nephrectomy and their families, INTERNATIONAL UROLOGY AND NEPHROLOGY, 50(6), 1061-1066, JUN 2018
  31. Normalization of C-reactive protein levels following cytoreductive nephrectomy in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors is associated with improved overall survival, UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 36(7), JUL 2018
  32. Preoperative risk classification using neutrophil-lymphocyte ratio and hydronephrosis for upper tract urothelial carcinoma, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 48(9), 841-849, SEP 2018
  33. Longitudinal analysis of laparoendoscopic single-site adrenalectomy and conventional laparoscopic adrenalectomy regarding patient-reported satisfaction and cosmesis outcomes, ASIAN JOURNAL OF SURGERY, 42(3), 514-519, 201903
  34. Fibroblast Growth Factor Family in the Progression of Prostate Cancer, JOURNAL OF CLINICAL MEDICINE, 8(2), 201902
  35. Endoscopic repair of the urinary bladder with magnetically labeled mesenchymal stem cells: Preliminary report, REGENERATIVE THERAPY, 10, 46-53, 201906
  36. Current status of prognostic factors in patients with metastatic renal cell carcinoma, INTERNATIONAL JOURNAL OF UROLOGY, 26(6), 608-617, 201906
  37. TUBB3 Reverses Resistance to Docetaxel and Cabazitaxel in Prostate Cancer, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(16), 20190802
  38. Predictors of poor response to first-generation anti-androgens as criteria for alternate treatments for patients with non-metastatic castration-resistant prostate cancer, INTERNATIONAL UROLOGY AND NEPHROLOGY, 52(1), 77-85, 202001
  39. Magnetic resonance imaging/transrectal ultrasonography fusion targeted prostate biopsy finds more significant prostate cancer in biopsy-naive Japanese men compared with the standard biopsy, INTERNATIONAL JOURNAL OF UROLOGY, 27(2), 140-146, 202002
  40. Prevalence of hand joint symptoms in androgen deprivation therapy among japanese patients with prostate cancer, UROLOGICAL SCIENCE, 31(1), 15-20, 2020
  41. Comparative analysis of robot-assisted, laparoscopic, and open radical prostatectomy regarding lower urinary tract symptoms: A longitudinal study, UROLOGICAL SCIENCE, 31(1), 21-27, 2020
  42. PTEN Is Involved in Sunitinib and Sorafenib Resistance in Renal Cell Carcinoma, ANTICANCER RESEARCH, 40(4), 1943-1951, 202004
  43. Improved prognosis for elderly patients with metastatic renal cell carcinoma in the era of targeted therapy, MOLECULAR AND CLINICAL ONCOLOGY, 12(6), 557-564, 202006
  44. Impact of radiological morphology of clinical T1 renal cell carcinoma on the prediction of upstaging to pathological T3, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 50(4), 473-478, 202004
  45. Renal metastasis from primary hepatocellular carcinoma: a case report, INTERNATIONAL CANCER CONFERENCE JOURNAL, 9(3), 141-145, 202007
  46. The Impact of Histological Variant on Oncological Outcomes in Patients With Urothelial Carcinoma of the Bladder Treated With Radical Cystectomy, ANTICANCER RESEARCH, 40(8), 4787-4793, 202008


  1. 2017/05/13, 112th AUA Annual Meeting,Best Poster Award., American Urological Association
  2. 2018/04/19, IJU Reviewers of the Year 2017, International journal of urology
  3. 2019/04/19, IJU Reviewers of the Year 2018, International journal of urology

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI, 2013, 2014
  2. KAKENHI, 2012, 2014
  3. KAKENHI, 2012, 2014
  4. KAKENHI, Regeneration of cavernous nerve after transplantation of CD 133+ cells derived from human peripheral blood and placement of biodegradable gel sponge sheet., 2010, 2011
  5. KAKENHI, Identification and translational research of transmenbrane and secretary proteins in prostate cancer, 2009, 2011
  6. KAKENHI, 2016, 2018
  7. KAKENHI, 2015, 2018