Toshiya Inaba

Last Updated :2023/06/01

Affiliations, Positions
Research Institute for Radiation Biology and Medicine, Professor
E-mail
tinabahiroshima-u.ac.jp

Basic Information

Academic Degrees

  • M.D., The University of Tokyo

Research Fields

  • Medicine,dentistry, and pharmacy;Basic medicine;General medical chemistry
  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Hematology

Educational Activity

Course in Charge

  1. 2023, Liberal Arts Education Program1, 2Term, War and Peace from the Viewpoint of Medicine
  2. 2023, Undergraduate Education, First Semester, Radiation Biology & Radiation Health Risk Sciences
  3. 2023, Graduate Education (Master's Program) , First Semester, Seminar
  4. 2023, Graduate Education (Master's Program) , Second Semester, Seminar
  5. 2023, Graduate Education (Master's Program) , First Semester, Research
  6. 2023, Graduate Education (Master's Program) , Second Semester, Research
  7. 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar
  8. 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar
  9. 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Research
  10. 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Research
  11. 2023, Graduate Education (Master's Program) , First Semester, Molecular Biology and Radiological Science
  12. 2023, Graduate Education (Doctoral Program) , 1Term, Integrated Radiation Medical Science
  13. 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Molecular Oncology
  14. 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Molecular Oncology
  15. 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Molecular Oncology
  16. 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Molecular Oncology
  17. 2023, Graduate Education (Doctoral Program) , Second Semester, Introduction to Radiation Biology

Research Activities

Academic Papers

  1. ★, Poly-ADP Ribosylation of Miki by tankyrase-1 Promotes Centrosome Maturation, MOLECULAR CELL, 47(5), 694-706, 20120914
    Link to Paper Search Results by DOI
  2. Oncogenic fusion E2A-HLF sensitizes t(17;19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors, LEUKEMIA, 26(12), 2483-2493, 201212
    Link to Paper Search Results by DOI
  3. Identification of the integrin beta 3 L718P mutation in a pedigree with autosomal dominant thrombocytopenia with anisocytosis, BRITISH JOURNAL OF HAEMATOLOGY, 160(4), 521-529, 201302
    Link to Paper Search Results by DOI
  4. ★, Reversal of Apoptosis by the leukemia-associated E2A-HLF Chimeric transcription factor, Nature, 382, 541, 19960401
  5. DNA binding specificity and trans-activating potential of the leukemia-associated E2A-HLF fusion protein, Molecular and Cellular Biology, 14, 3403, 19940401
  6. Genomic organization, chromosome localization, and independent expression of human cyclin D genes., Genomics, 13, 565-574, 19920401
  7. Functional and molecular characteristics of acute lymphoblastic leukemia cells with a mature T-cell phenotype from a patient with ataxia telangiectasia., Leukemia, 5, 88-89, 19920401
  8. Molecular analysis of bcr/abl products in a case of myelodysplastic syndrome with late appearing Philadelphia chromosome., Br J Haematol, 78, 130-132, 19910401
  9. Characterization of an embryonal rhabdomyosarcoma cell line showing amplification and over-expression of the N-myc oncogene., Int J Cancer, 705-711, 19900401
  10. Karyotypic patterns of acute mixed lineage leukemia., Leukemia, 4, 121-126, 19900401
  11. Heterogeneity in the breakpoints of chromosome 19 among acute leukemic patients with the t(11;19)(q23;p13) tranlocation., Am. J. Hematol. =, 31, 253-257, 19890401
  12. Fatal infectious mononucleosis with staphylococcal pyoderma in a girl with hereditary immunological dysregulations., Eur J Pediatr, 149, 177-178, 19890401
  13. Similar chromosomal patterns and lack of N-myc gene amplification localized and IV-S stage neuroblastoma in infants., Med. Pedatr. Oncol., 17, 111-115, 19890401
  14. Cytogenetic findings and prognosis in neuroblastoma with emphasis on marker chromosome 1., Cancer, 63, 126-132, 19890401
  15. The e2a-hlf oncoprotein activates groucho-related genes and suppresses runx1., Mol. Cell. Biol., 21, 5935-5945, 20010401
  16. Erythropoietin regulates vascular smooth muscle cell apoptosis by a phosphatidylinositol 3 kinase-dependent pathway., Kidney Int., 58, 269-282, 20000401
  17. Involvement of mTOR/Bim, not Akt/Bad pathway in cytokine-mediated cells survival signaling downstream of PI3-kinase in murine hematopoietic progenitors., Blood 96 Suppl., 1, 568A, 20000401
  18. Expression of E2A-HLF chimeric protein induced T-cell apoptosis, B-cell maturation arrest and development of acute lymphoblastic leukemia., Blood, 93, 2780-2790, 19990401
  19. Two distinct interleukin-3-mediated signal pathways, Ras-NFIL3(E4BP4) and Bcl-xL, regulate the survival of murine pro-B lymphocytes., Mol. Cell. Biol., 19, 2754-2762, 19990401
  20. SLUG, a ces-1-related zinc-finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein., Mol. Cell, 4, 343-352, 19990401
  21. Expression patterns of the hepatic leukemia factor gene in the nervous system of developing and adult mice., Brain Res., 820, 1-11, 19990401
  22. Anti-tumor activity of antizyme which targets the ornithine decarboxylase (ODC) required for cell growth and transformation., Oncogene, 18, 165-172, 19990401
  23. Two candidate downstream target genes for E2A-HLF., Blood, 93, 321-332, 19990401
  24. Essential role of the BH3 factor, Bim, in the cytokine-mediated apoptosis program: Implications in the antiapoptotic Ras pathways and in leukemogenesis., Blood 94 Suppl., 1, 688A, 19990401
  25. Thyrotroph embryonic factor is a possible regulatory factor maintaining the quiscent hematopoietic progenitors., Blood 94 Suppl., 1, 271A, 19990401
  26. The AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the E2A-HLF chimeric oncoprotein., Mol. Cell. Biol., 18, 6035-6043, 19980401
  27. Transcription factor NF-E2 is essential for the polyploidization of a human megakaryoblastic cell line, Meg-J., Biochem. Biophys. Res. Commun., 247, 65-69, 19980401
  28. Involvement of Bim, the BH3-containing cell death activator, in cytokine-mediated apoptosis program and in leukemogenesis by the E2A-HLF chimera, Blood 92 Suppl., 1, 199A, 19980401
  29. Identification of the antiapoptotic zinc-finger transcription factor SLUG as a target of E2A-HLF oncogenic fusion protein., Blood 92 Suppl., 1, 479A, 19980401
  30. Groucho-related genes are activated by the E2A-HLF chimeric oncoprotein In FL5.12 cells., Blood 92 Suppl., 1, 589A, 19980401
  31. Downstream target genes for E2A-HLF Identified by cDNA microarray analysis., Blood 92 Suppl., 1, 590A, 19980401
  32. Development of a novel selective amplifier gene for controllable expansion of transduced hematopoietic cells., Blood, 90, 3884-3892, 19970401
  33. Pivotal role for the NFIL3/E4BP4 transcription factor in IL-3-mediated survival of pro-B lymphocytes., Proc. Natl. Acad. Sci. USA, 94, 2609-2614, 19970401
  34. Cell transformation mediated by homodimeric E2A-HLF transcription factors., Mol. Cell. Biology, 17, 1417-1424, 19970401
  35. Ras-dependent and -independent regulation of E4BP4/NFIL3 transcription factor in cytokine-mediated cell survival of pro-B lymphocytes: the target gene program for oncogenic Ras, Bcr-Abl and E2A-HLF chimeras in leukemogenesis., Blood 90 Suppl., 1, 47A, 19970401
  36. Thyrotroph embryonic factor (TEF) is capable of regulating the cell cycle and cell survival of lymphoid cells., Blood 90 Suppl., 1, 138A, 19970401
  37. Anti-apoptotic effects of E2A-HLF: Evidence for mechanisms involving both gain and loss of function., Blood 88(10) Supple., 1(10), 552A, 19960401
  38. E4BP4, an IL-3-responsive bZIP transcription factor, contributes to cell survival in mouse pro-B cells., Blood 88(10) Supple., 1(10), 658A, 19960401
  39. E2A-HLF-mediated cell transformation requires both the trans-activation domains of E2A and the leucine zipper dimerization domain of HLF., Mol. Cell. Biology, 15, 3247-3255, 19950401
  40. The E2A-HLF fusion protein as a direct hmodimeric trans-activator of downstream target genes in malignant transformation., abstr. Blood 86(10) Supple., 1(10), 39A, 19950401
  41. The oncogenc E2A-HLF fusion protein protects leukemic B-precursor cells from apotosis., abstr. Blood 86(10) Supple., 1(10), 327A, 19950401
  42. Chromosomal localization and cDNA cloning of the human DBP and TEF genes., Genomics, 23, 344-351, 19940401
  43. Differential molecular consequences of the 1;19 chromosomal translocation in childhood B-cell precursor acute lymphoblastic leukemia., Blood, 79, 1781-1785, 19920401
  44. Differential expression of myogenic regulatory genes, MyoD1 and myogenin, in human rhabdomyosarcoma sublines., Int J Cancer, 50, 977-983, 19920401
  45. Chromosome findings and prognosis in 15 patients with neuroblastoma found by VMA mass screening., J. Pediatr., 112, 567-571, 19880401
  46. Translocation 2;8 in a congenital rhabdomyosarcoma., Cancer Genet.Cytogenet., 30, 343-345, 19880401
  47. Enhancement of thymidine kinase-mediated killing of malignant glioma by BimS, a BH3-only cell death activator, Gene Therapy, 10(5), 375-385, 20030301
  48. Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors., Mol. Cell. Biol., 21, 854-864, 20010501
  49. The expression of Bcl-2 family proteins (Bcl-2, Bcl-x, Bax, Bak and Bim) in human lymphocytes., Immunol Lett, 81, 107-113, 20020501
  50. Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome / acute myeloid leukemia., Blood, 101, 673-680, 20030501
  51. Regulation of osteoclast apoptosis by ubiqutination of proapoptotic BH3-only Bcl-2 family member Bim., EMBO J., 22, 6653-6664, 20030501
  52. High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia., Blood, 103, 2316-2324, 20041001
  53. Regulation of annexin II by cytokine-initiated signaling pathways and E2A-HLF oncoprotein., Blood, 103, 3185-3191, 20041001
  54. Deletion 6p23 and add(11)(p15) leading to NUP98 translocation in a case of therapy-related atypical chronic myelocytic leukemia transforming to acute myelocytic leukemia., Cancer Genet. Cytogenet., 152, 56-60, 20041001
  55. The Adenovirus E1A and E1B19K genes provide a helper function for transfection-based AAV vector production., J. Gen.Virol., 85, 2009-2014, 20041001
  56. TEF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by downregulating expression of the common b chain of cytokine receptors., Blood, 105, 4437-4444, 20051001
  57. Structure of the human Bim gene and its transcriptional regulation in Baf-3, interleukin-3-dependent hematopoietic cells., Mol. Biol. Rep., 32, 79-85, 20051001
  58. Neuroprotective effects of erythropoietin on glutamate and nitric oxide toxicity in primary cultured retinal ganglion cells., Brain Res., 1050, 15-26, 20051001
  59. Hyperactivation of the RAS signaling pathway in myelodysplastic syndrome with AML1/RUNX1 point mutations., Leukemia, 20, 635-644, 20061001
  60. Cytokines direct the regulation of Bim mRNA stability by Heat shock cognate protein 70., Mol. Cell, 25, 99-112, 20071001
  61. Hypercalcemia in childhood acute lymphoblastic leukemia:frequent implication of PTHrP and E2A-HLF from translocation 17;19., Leukemia, 21, 288-296, 20071001
  62. Hyperactivation of the RAS signaling pathway in myelodysplastic syndromewith AML1/RUNX1 point mutations., Leukemia, 20, 635-644, 20061001
  63. Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors, MOLECULAR AND CELLULAR BIOLOGY, 21(3), 854-864, 200102
    Link to Paper Search Results by DOI
  64. Establishment of the acute myeloid leukemia cell line Kasumi-6 from a patient with a dominant-negative mutation in the DNA-binding region of the C/EBP alpha gene, GENES CHROMOSOMES & CANCER, 36(2), 167-174, 200302
    Link to Paper Search Results by DOI
  65. Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia, BLOOD, 101(2), 673-680, 20030115
    Link to Paper Search Results by DOI
  66. Enhancement of thymidine kinase-mediated killing of malignant glioma by BimS, a BH3-only cell death activator, GENE THERAPY, 10(5), 375-385, 200303
    Link to Paper Search Results by DOI
  67. Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim, EMBO JOURNAL, 22(24), 6653-6664, 20031215
    Link to Paper Search Results by DOI
  68. High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia, BLOOD, 103(6), 2316-2324, 20040315
    Link to Paper Search Results by DOI
  69. Regulation of annexin II by cytokine-initiated signaling pathways and E2A-HLF oncoprotein, BLOOD, 103(8), 3185-3191, 20040415
    Link to Paper Search Results by DOI
  70. Deletion 6p23 and add(II)(p15) leading to NUP98 translocation in a case of therapy-related atypical chronic myelocytic leukemia transforming to acute myelocytic leukemia, CANCER GENETICS AND CYTOGENETICS, 152(1), 56-60, 20040701
    Link to Paper Search Results by DOI
  71. Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors, MOLECULAR AND CELLULAR BIOLOGY, 24(14), 6172-6183, 200407
    Link to Paper Search Results by DOI
  72. The adenovirus E1A and E1B19K genes provide a helper function for transfection-based adeno-associated virus vector production, JOURNAL OF GENERAL VIROLOGY, 85, 2209-2214, 200408
    Link to Paper Search Results by DOI
  73. TEF, an antiapoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by down-regulating expression of the common beta chain of cytokine receptors, BLOOD, 105(11), 4437-4444, 20050601
    Link to Paper Search Results by DOI
  74. Structure of the human Bim gene and its transcriptional regulation in Baf-3, interleukin-3-dependent hematopoietic cells, MOLECULAR BIOLOGY REPORTS, 32(2), 79-85, 200506
    Link to Paper Search Results by DOI
  75. Neuroprotective effects of erythropoietin on glutamate and nitric oxide toxicity in primary cultured retinal ganglion cells, BRAIN RESEARCH, 1050(1-2), 15-26, 20050719
    Link to Paper Search Results by DOI
  76. Nuclear abnormalities in aspirated thyroid cells and chromosome aberrations in lymphocytes of residents near the Semipalatinsk Nuclear Test Site, JOURNAL OF RADIATION RESEARCH, 47, A171-A177, 200602
    Link to Paper Search Results by DOI
  77. Protein kinase B/Akt signalling is required for palmitate-induced beta-cell lipotoxicity, DIABETES OBESITY & METABOLISM, 8(2), 228-233, 200603
    Link to Paper Search Results by DOI
  78. Hyperactivation of the RAS signaling pathway in myelodysplastic syndrome with AML1/RUNX1 point mutations, LEUKEMIA, 20(4), 635-644, 200604
    Link to Paper Search Results by DOI
  79. Unstable-type chromosome aberrations in lymphocytes from individuals living near Semipalatinsk Nuclear Test Site, JOURNAL OF RADIATION RESEARCH, 47, A159-A164, 200602
    Link to Paper Search Results by DOI
  80. Cytokines direct the regulation of Bim mRNA stability by heat-shock cognate protein 70, MOLECULAR CELL, 25(1), 99-112, 20070112
    Link to Paper Search Results by DOI
  81. Hypercalcemia in childhood acute lymphoblastic leukemia: frequent implication of parathyroid hormone-related peptide and E2A-HLF from translocation 17;19, LEUKEMIA, 21(2), 288-296, 200702
    Link to Paper Search Results by DOI
  82. AML1 mutations induced MDS and MDS/AML in a mouse BMT model, BLOOD, 111(8), 4297-4308, 20080415
    Link to Paper Search Results by DOI
  83. Peptidoglycan and lipopolysaccharide activate PLC gamma 2, leading to enhanced cytokine production in macrophages and dendritic cells, GENES TO CELLS, 13(2), 199-208, 200802
    Link to Paper Search Results by DOI
  84. Ras-mediated up-regulation of survivin expression in cytokine-dependent murine pro-B lymphocytic cells, TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 216(1), 25-34, 200809
    Link to Paper Search Results by DOI
  85. Haploinsufficiency and acquired loss of Bcl11b and H2AX induces blast crisis of chronic myelogenous leukemia in a transgenic mouse model, CANCER SCIENCE, 100(7), 1219-1226, 200907
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  86. Identification of a common microdeletion cluster in 7q21.3 subband among patients with myeloid leukemia and myelodysplastic syndrome, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 383(2), 245-251, 20090529
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  87. Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19), BLOOD, 116(6), 962-970, 20100812
    Link to Paper Search Results by DOI
  88. A 5 ' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model, DEVELOPMENTAL BIOLOGY, 345(2), 226-236, 20100915
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  89. Rapid Emergence of Telaprevir Resistant Hepatitis C Virus Strain from Wildtype Clone In Vivo, HEPATOLOGY, 54(3), 781-788, 201109
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  90. Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma, BRITISH JOURNAL OF CANCER, 104(1), 91-100, 20110104
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  91. The Dynactin Complex Maintains the Integrity of Metaphasic Centrosomes to Ensure Transition to Anaphase, JOURNAL OF BIOLOGICAL CHEMISTRY, 286(7), 5589-5598, 20110218
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  92. The Samd9L Gene: Transcriptional Regulation and Tissue-Specific Expression in Mouse Development, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 131(7), 1428-1434, 201107
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  93. A Modified System for Analyzing Ionizing Radiation-Induced Chromosome Abnormalities, RADIATION RESEARCH, 177(5), 533-538, 201205
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  94. Mouse Samd9l is not a functional paralogue of the human SAMD9, the gene mutated in normophosphataemic familial tumoral calcinosis, EXPERIMENTAL DERMATOLOGY, 21(7), 554-556, 201207
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  95. Combination therapies with NS5A, NS3 and NS5B inhibitors on different genotypes of hepatitis C virus in human hepatocyte chimeric mice, GUT, 62(7), 1055-1061, 201307
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  96. Diverse underlying proliferation response to growth factors in imatinib-treated Philadelphia chromosome-positive leukemias, LEUKEMIA RESEARCH, 37(1), 93-101, 201301
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  97. ★, Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7, CANCER CELL, 24(3), 305-317, 20130909
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  98. Acquired Deficiency of A20 Results in Rapid Apoptosis, Systemic Inflammation, and Abnormal Hematopoietic Stem Cell Function, PLOS ONE, 9(1), 20140131
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  99. MLL fusion proteins link transcriptional coactivators to previously active CpG-rich promoters, NUCLEIC ACIDS RESEARCH, 42(7), 4241-4256, 201404
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  100. Novel functional small RNAs are selectively loaded onto mammalian Ago1, NUCLEIC ACIDS RESEARCH, 42(8), 5289-5301, 201404
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  101. Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation, NATURE COMMUNICATIONS, 5, 201406
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  102. AS-2, a novel inhibitor of p53-dependent apoptosis, prevents apoptotic mitochondrial dysfunction in a transcription-independent manner and protects mice from a lethal dose of ionizing radiation, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 450(4), 1498-1504, 20140808
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  103. A Novel ATM/TP53/p21-Mediated Checkpoint Only Activated by Chronic gamma-Irradiation, PLOS ONE, 9(8), 20140805
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  104. Emergence of resistant variants detected by ultra-deep sequencing after asunaprevir and daclatasvir combination therapy in patients infected with hepatitis C virus genotype 1, JOURNAL OF VIRAL HEPATITIS, 22(2), 158-165, 201502
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  105. SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS, LEUKEMIA, 29(4), 847-857, 201504
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  106. -7/7q-syndrome in myeloid-lineage hematopoietic malignancies: attempts to understand this complex disease entity, ONCOGENE, 34(19), 2413-2425, 20150507
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  107. Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2, BLOOD, 125(22), 3437-3446, 20150528
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  108. Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency, SCIENTIFIC REPORTS, 6, 20160719
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  109. Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia, EXPERIMENTAL HEMATOLOGY, 44(8), 745-754, 201608
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  110. Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(37), 10370-10375, 20160913
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  111. Identification of cooperative genes for E2A-PBX1 to develop acute lymphoblastic leukemia, CANCER SCIENCE, 107(7), 890-898, 201607
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  112. Acquired expression of Cbl(Q367P) in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia, BLOOD, 129(15), 2148-2160, 20170413
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  113. Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes, NATURE COMMUNICATIONS, 8, 20170926
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  114. A novel LSD1 inhibitor NCD38 ameliorates MDS-related leukemia with complex karyotype by attenuating leukemia programs via activating super-enhancers, LEUKEMIA, 31(11), 2303-2314, 201711
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  115. Dose-response curves for analyzing of dicentric chromosomes and chromosome translocations following doses of 1000 mGy or less, based on irradiated peripheral blood samples from five healthy individuals, JOURNAL OF RADIATION RESEARCH, 59(1), 35-42, 201801
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  116. A Chemical Modulator of p53 Transactivation that Acts as a Radioprotective Agonist, MOLECULAR CANCER THERAPEUTICS, 17(2), 432-442, 201802
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  117. A novel ASXL1-OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies, LEUKEMIA, 32(6), 1327-1337, 201806
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  118. The enigma of monosomy 7, BLOOD, 131(26), 2891-2898, 20180628
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