Last Updated :2024/02/01

Affiliations, Positions
Hiroshima University Hospital(Medical), Associate Professor or Lecturer
Other Contact Details
1-2-3 Kasumi Minami-ku Hiroshima, Japan
TEL : (+81)82-257-5193 FAX : (+81)82-257-5194
I am taking care of pancreatic biliary tract diseases. Especially we are focusing on early diagnosis of pancreatic cancer.

Basic Information

Major Professional Backgrounds

  • 1997/05/16, 1998/03/30, Hiroshima University, Medical Hospital, Clinical Resident
  • 1998/04/01, 1998/09/30, Hiroshima General Hospital of West Japan Railwey Company, Medical Hospital, Clinical Resident
  • 1998/10/01, 1999/03/30, Hiroshima University, Medical Hospital, Clinical Resident
  • 1999/04/01, 2001/03/31, National Hospital Organization Higashihiroshima Medical Center, Medical Hospital, Medicall Doctor
  • 2001/04/01, 2002/03/31, Miyoshi Central Hospital, Medical Hospital, Medicall Doctor
  • 2002/04/01, 2003/03/31, Yamasaki Hospital , Medical Hospital, Medicall Doctor
  • 2007/04/01, 2010/03/31, Hiroshima University Hospital, Medical Hospital, Clinical Fellow
  • 2010/04/01, Hiroshima University, Medical Hospital, Assistant Professor
  • 2016/06/01, Hiroshima University, Medical Hospital, Clinical Lecturer
  • 2019/12/01, Hiroshima University, Hospital, Lecturer

Educational Backgrounds

  • Hiroshima University, Japan, 1991/04, 1997/03
  • Hiroshima University, Graduate School of Biomedical Sciences, Japan, 2003/04, 2007/03

Academic Degrees

  • Doctor of Philosophy in Medical Science, Hiroshima University

Educational Activity

  • [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine

In Charge of Primary Major Programs

  • Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Gastroenterology

Research Keywords

  • pancreatic biliary tract diseases early diagnosis of pancreatic cancer.

Affiliated Academic Societies

  • nihon naika gakkai
  • nihon naisikyou gakkai
  • nihon syoukakibyou gakkai
  • nihon gantiryou gakkai
  • nihon suizougakkai
  • nihon tandougakkai

Educational Activity

Course in Charge

  1. 2023, Undergraduate Education, Year, Clinical diagnosis and treatment I
  2. 2023, Undergraduate Education, Intensive, Practice of Medicine I
  3. 2023, Undergraduate Education, Intensive, Practice of Medicine II
  4. 2023, Undergraduate Education, First Semester, Internal Medicine I
  5. 2023, Graduate Education (Master's Program) , Second Semester, General Clinical Medicine and Dentistry

Research Activities

Academic Papers

  1. Utility of the inside stent as a preoperative biliary drainage method for patients with malignant perihilar biliary stricture, JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 28(10), 864-873, 202110
  2. Is surgery justified for elderly patients with extrahepatic cholangiocarcinoma? Reappraisal from a viewpoint of comorbidity and organ function, SURGERY TODAY, 51(11), 1787-1794, 202111
  3. Elevated expression of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 in primary sclerosing cholangitis: Implications for cholangiocarcinogenesis, INTERNATIONAL JOURNAL OF ONCOLOGY, 43(4), 1073-1079, 20131001
  4. A comparative study of 4 Fr versus 6 Fr nasobiliary drainage catheters: A randomized, controlled trial, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29(3), 653-659, 20140301
  5. Gemcitabine suppresses malignant ascites of human pancreatic cancer: correlation with VEGF expression in ascites., Oncol Rep., 11, 73-80, 20040101
  6. The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines, INTERNATIONAL JOURNAL OF ONCOLOGY, 28(4), 915-921, 20060401
  7. Management of intraductal papillary-mucinous neoplasm of the pancreas - Treatment strategy based on morphologic classification, JOURNAL OF CLINICAL GASTROENTEROLOGY, 40(9), 856-862, 20061001
  8. Expression of multidrug resistance-associated protein 2 is involved in chemotherapy resistance in human pancreatic cancer, INTERNATIONAL JOURNAL OF ONCOLOGY, 33(6), 1187-1194, 20081201
  9. Statins induce apoptosis and inhibit proliferation in cholangiocarcinoma cells, INTERNATIONAL JOURNAL OF ONCOLOGY, 39(3), 561-568, 20110901
  10. Assessment of Trypsinogen-2 Levels as an Early Diagnostic for Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis, PANCREAS, 40(8), 1206-1210, 20111101
  11. The effect of respiratory-gated positron emission tomography/computed tomography in patients with pancreatic cancer, HELLENIC JOURNAL OF NUCLEAR MEDICINE, 17(1), 31-36, 20140401
  12. Timing of radiological improvement after steroid therapy in patients with autoimmune pancreatitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 49(6), 727-733, 20140601
  13. Antibiotic prophylaxis for endoscopic retrograde chlangiopancreatography increases the detection rate of drug-resistant bacteria in bile, JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 21(9), 712-718, 20140901
  14. Occupational Radiation Exposure during Endoscopic Retrograde Cholangiopancreatography and Usefulness of Radiation Protective Curtains, GASTROENTEROLOGY RESEARCH AND PRACTICE, 20140401
  15. Evaluation of Antibiotic Use to Prevent Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Cholangitis, HEPATO-GASTROENTEROLOGY, 62(138), 417-424, 20150301
  16. Characteristic Features of Cholangiocarcinoma Complicating Primary Sclerosing Cholangitis, HEPATO-GASTROENTEROLOGY, 61(131), 567-573, 20140501
  17. Preoperative Biliary Drainage in Cases of Borderline Resectable Pancreatic Cancer Treated with Neoadjuvant Chemotherapy and Surgery, GASTROENTEROLOGY RESEARCH AND PRACTICE, 20160106
  18. The Role of the selective Arterial Secretagogue Injection Test for Non-Functional Pancreatic Neuroendocrine Tumor, JOURNAL OF THE PANCREAS, 16(6), 601-606, 20151109
  19. A comparison of 4Fr with 5Fr endoscopic nasopancreatic drainage catheters:A randomized,controlled trial, J Gastroenterol Hepatol, 31(10), 1783-1789, 20161027
  20. Two Cases of Mucinous(Non-Cystic)Carcinoma of the Pancreas Without Intraductal Papillary Mucinous Neoplasm, Pancreas, 45(6), 924-925, 20151001
  21. The Role of the Selective Arterial Secretagogue Injection Test for Non-Functional Pancreatic Neuroendocrine Tumor, JOURNAL OF THE PANCREAS, 16(6), 601-606, 201511
  22. A comparison of 4-Fr with 5-Fr endoscopic nasopancreatic drainage catheters: A randomized, controlled trial, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(10), 1783-1789, 201610
  23. Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus, PLOS ONE, 12(3), 20170302
  24. Clinical features and predictive value of serum inflammatory markers of perivascular involvement in immunoglobulin G4-related disease, Heart VesselsDOI 10.1007/s00380-017-0987-2(Heart VesselsDOI 10.1007/s00380-017-0987-2), 2017
  25. Use of 4-Fr versus 6-Fr Nasobiliary Catheter for Biliary Drainage : A Prospective, Multicenter, Randomized, Controlled Study, Diagnostic and Therapeutic Endoscopy, 7156719 7(7156719 7), 2017
  26. Multicenter study of early pancreatic cancer in Japan, PANCREATOLOGY, 18(1), 61-67, 201801
  27. Indication and Usefulness of Bile Juice Cytology for Diagnosis of Gallbladder Cancer, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2018
  28. Management of Pancreatolithiasis: A Nationwide Survey in Japan, PANCREAS, 47(6), 708-714, 201807
  29. Clinical guidelines for primary sclerosing cholangitis 2017, JOURNAL OF GASTROENTEROLOGY, 53(9), 1006-1034, 201809
  30. Impact of sclerosing dacryoadenitis/sialadenitis on relapse during steroid therapy in patients with type 1 autoimmune pancreatitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 54(2), 259-264, 20190201
  31. Investigation of Fluorodeoxyglucose Positron Emission Tomography for the Diagnosis of Solid Pseudopapillary Neoplasm of the Pancreas A Study Associated With a National Survey of Solid Pseudopapillary Neoplasms, PANCREAS, 48(10), 1312-1320, 2019
  32. Transabdominal Ultrasound Real-time Tissue Elastography as a Screening Method for Early Chronic Pancreatitis, Hiroshima Journal of Medical Sciences, 68(2・3), 35-41
  33. Prediction of the Probability of Malignancy in Mucinous Cystic Neoplasm of the Pancreas With Ovarian-Type Stroma A Nationwide Multicenter Study in Japan, PANCREAS, 49(2), 181-186, 202002
  34. New surgical technique for pancreatic lithotripsy without coring-out, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(6), 1343-1346, 202012
  35. Role of Endoscopic Ultrasonography and Endoscopic Retrograde Cholangiopancreatography in the Diagnosis of Pancreatic Cancer, DIAGNOSTICS, 11(2), 202102
  36. Clinical Analysis of Early-Stage Pancreatic Cancer and Proposal for a New Diagnostic Algorithm: A Multicenter Observational Study, DIAGNOSTICS, 11(2), 202102
  37. Clinical Usefulness of Serum Autotaxin for Early Prediction of Relapse in Male Patients with Type 1 Autoimmune Pancreatitis, DIGESTIVE DISEASES AND SCIENCES, 66(4), 1268-1275, 202104
  38. yRibavirin induces hepatitis C virus genome mutations in chronic hepatitis patients who failed to respond to prior daclatasvir plus asunaprevir therapy, JOURNAL OF MEDICAL VIROLOGY, 92(2), 210-218, 202002
  39. The role of apparent diffusion coefficient value in the diagnosis of localized type 1 autoimmune pancreatitis: differentiation from pancreatic ductal adenocarcinoma and evaluation of response to steroids, ABDOMINAL RADIOLOGY, 46(5), 2014-2024, 202105
  40. Preoperative risk factors for para-aortic lymph node positivity in pancreatic cancer, PANCREATOLOGY, 21(3), 606-612, 202104
  41. The prognostic impact of peritoneal washing cytology for otherwise resectable extrahepatic cholangiocarcinoma patients, SURGERY TODAY, 51(7), 1227-1231, 202107
  42. Endoscopic placement of covered versus uncovered self-expandable metal stents for palliation of malignant gastric outlet obstruction, GUT, 70(7), 1244-+, 202107

Publications such as books

  1. 2007/04/01, Management of intraductal papillary-mucinous neoplasm of the pancreas : treatment strategy based on morphologic classification, Scholarly Book, Single work

Invited Lecture, Oral Presentation, Poster Presentation

  1. Usefulness of gallbladder bile cytology with ENGBD in differential diagnosis of gallbladder cancer., Tetsuro Hirano,, Masahiro Serikawa,Kazuaki Chayama, The 56th Annual Meeting of the Japan Biliary Association, 2020/10/01, Without Invitation, English
  2. Examination About The Relation Between Imaging Findings And Histological Grade Diagnosis For Pancreatic Neuroendocrine Neoplasm (Pan-NEN), Hirano T , Serikawa M, Ishii Y, Tsuboi T, Kawamura R, tsushima K,Saituoh Y,Sekitou T, Nakamura S, Fukiage A, , Ikemoto J, Kiyoshita Y,Saeki S,Tamura Y,Chayama K,, 2019/11/07, Without Invitation, English
  3. The utility of the 4Fr nasobiliary drainage catheter: Prospective multicenter,randomized,controlled study, Tsuboi T, Serikawa M, Ishii Y, Fujimoto Y, Ishigaki T, Yamaguchi A, Kuwabara K, Sasaki T, Shimizu A, Chayama K, Asia Pacific Digestive Week (APDW), 2016/11/05, Without Invitation, English
  4. Development of an early screening method for chronic pancreatitis using real-time-elastography, Shimizu A, Serikawa M, Ishii Y, Tsuboi T, Kurihara K, Tatsukawa Y, Miyaki E, Kawamura R, Tsushima K, Chayama K, Asia Pacific Digestive Week (APDW), 2016/11/04, Without Invitation, English

Social Activities

History as Committee Members

  1. nihon syoukakinaisikyougakkai
  2. nihonnsyoukakigazousinndannkennkyuukaisewaninnkai
  3. nihon syoukakibyougakkai