GRACE NASWA MAKOKHA

Last Updated :2023/06/01

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medicine), Assistant Professor (Special Appointment)
E-mail
gnaswahiroshima-u.ac.jp

Basic Information

Major Professional Backgrounds

  • 2017/04, Institute of Biomedical & Health Sciences, Hiroshima University, Assistant professor (Specially Appointed)
  • 2014/04/01, 2015/03/31, Hiroshima University, Institute of Biomedical & Health Sciences, Researcher
  • 2015/04/01, 2017/03/31, Hiroshima University, Institute of Biomedical & Health Sciences, Assistant Professor

Educational Backgrounds

  • Niigata University, Japan, 2009/10, 2013/09
  • Maseno University, Biomedical Sciences, Biomedical Sciences and Technology, Kenya, 2002/01, 2006/12

Academic Degrees

  • PhD in Medical Sciences, Niigata University

Affiliated Academic Societies

Research Activities

Academic Papers

  1. Construction of an anti-hepatitis B virus preS1 antibody and usefulness of preS1 measurement for chronic hepatitis B patients Anti-HBV PreS1 antibody, JOURNAL OF INFECTION, 84(3), 391-399, 202203
    Link to Paper Search Results by DOI
  2. Early events in hepatitis B virus infection: From the cell surface to the nucleus, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(2), 302-309, 201602
    Link to Paper Search Results by DOI
  3. Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection, JOURNAL OF GASTROENTEROLOGY, 51(11), 1073-1080, 201611
    Link to Paper Search Results by DOI
  4. Protease Inhibitor Resistance Remains Even After Mutant Strains Become Undetectable by Deep Sequencing, JOURNAL OF INFECTIOUS DISEASES, 214(11), 1687-1694, 20161201
    Link to Paper Search Results by DOI
  5. Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus, PLOS ONE, 12(3), 20170302
    Link to Paper Search Results by DOI
  6. Real-world efficacy and safety of daclatasvir and asunaprevir therapy for hepatitis C virus-infected cirrhosis patients, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 32(3), 645-650, 201703
    Link to Paper Search Results by DOI
  7. ITPA polymorphism effects on decrease of hemoglobin during sofosbuvir and ribavirin combination treatment for chronic hepatitis C, JOURNAL OF GASTROENTEROLOGY, 52(6), 746-753, 201706
    Link to Paper Search Results by DOI
  8. Development of a Novel Site-Specific Pegylated Interferon Beta for Antiviral Therapy of Chronic Hepatitis B Virus, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61(6), 201706
    Link to Paper Search Results by DOI
  9. Usefulness of humanized cDNA-uPA/SCID mice for the study of hepatitis B virus and hepatitis C virus virology, JOURNAL OF GENERAL VIROLOGY, 98(5), 1040-1047, 201705
    Link to Paper Search Results by DOI
  10. Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy, JOURNAL OF GASTROENTEROLOGY, 53(1), 107-118, 201801
    Link to Paper Search Results by DOI
  11. Persistent Loss of Hepatitis B Virus Markers in Serum without Cellular Immunity by Combination of Peginterferon and Entecavir Therapy in Humanized Mice, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61(9), 201709
    Link to Paper Search Results by DOI
  12. Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 500(2), 152-157, 20180602
    Link to Paper Search Results by DOI
  13. Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure, JOURNAL OF GENERAL VIROLOGY, 99(8), 1058-1065, 201808
    Link to Paper Search Results by DOI
  14. Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes, Virology, 525, 48-61, 201809
  15. CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic hepatitis B patients, Journal of Viral Hepatitis, 2018
  16. The association between serum cytokine and chemokine levels and antiviral response by entecavir treatment in chronic hepatitis B patients, Antiviral Therapy, 23(3), 239-248, 2017
  17. HTLV-1 Tax oncoprotein stimulates ROS production and apoptosis in T cells by interacting with USP10, Blood, 122(5), 715-725, 201308
  18. Both G3BP1 and G3BP2 contribute to stress granule formation, Genes to Cells, 18(2), 135-146, 201302
  19. Human T-cell leukemia virus type 1 Tax protein interacts with and mislocalizes the PDZ domain protein MAGI-1, Cancer Science, 104(3), 313-320, 2013
  20. CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic hepatitis B patients, JOURNAL OF VIRAL HEPATITIS, 25(12), 1555-1564, 201812
    Link to Paper Search Results by DOI
  21. Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes, VIROLOGY, 525, 48-61, 201812
    Link to Paper Search Results by DOI
  22. The association between serum cytokine and chemokine levels and antiviral response by entecavir treatment in chronic hepatitis B patients, ANTIVIRAL THERAPY, 23(3), 239-248, 2018
    Link to Paper Search Results by DOI
  23. Regulation of the Hepatitis B virus replication and gene expression by the multi-functional protein TARDBP, SCIENTIFIC REPORTS, 9, 20190611
    Link to Paper Search Results by DOI
  24. Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice, JOURNAL OF GASTROENTEROLOGY, 54(7), 650-659, 201907
    Link to Paper Search Results by DOI
  25. Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice, JOURNAL OF GENERAL VIROLOGY, 100(7), 1123-1131, 201907
    Link to Paper Search Results by DOI
  26. Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib, THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 12, 202005
    Link to Paper Search Results by DOI
  27. Signal Activation of Hepatitis B Virus-Related Hepatocarcinogenesis by Up-regulation of SUV39h1, JOURNAL OF INFECTIOUS DISEASES, 222(12), 2061-2070, 20201215
    Link to Paper Search Results by DOI
  28. In vitro analysis of hepatic stellate cell activation influenced by transmembrane 6 superfamily 2 polymorphism, MOLECULAR MEDICINE REPORTS, 23(1), 202101
    Link to Paper Search Results by DOI

Invited Lecture, Oral Presentation, Poster Presentation

  1. TARDBP regulates HBV transcription and replication through interaction with the core promoter, The Liver Meeting 2017, 2017/10/22, Without Invitation, English