TOMOHIKO KISAKA

Last Updated :2020/11/07

Affiliations, Positions
Bio design Division, Associate Professor
E-mail
tkisakahiroshima-u.ac.jp

Basic Information

Major Professional Backgrounds

  • 2005/04, 2009/03, Chugoku Rosai Hospital, Clinical Fellow
  • 2013/04, 2013/06, Hiroshima University Hospital, Heart Failure Center, Part-time Physician
  • 2013/06, 2016/12, California State University, Los Angeles, Harbor-UCLA Medical Center, Pulmonary and Critical Care Physiology and Medicine, Researcher
  • 2017/01, 2017/12, Hiroshima University, Center for Collaborative Research & Community Cooperation, Assistant Professor (Special Appointment)
  • 2017/02, 2018/01, All India Institute of Medical Sciences (AIIMS), School of International Biodesign (SiB), Department of Cardiology, iFellow
  • 2018/01, 2019/01, Hiroshima University Hospital, Assistant Professor
  • 2018/10, 2021/03, Hiroshima Prefectural Government, Commerce, Industry and Labor Bureau, Project Team for Medical-Technology Collaboration, Lead Cordinator
  • 2019/02, 2020/06, Hiroshima University, Translational Research Center, Division Chair of Biodesign, Associate Professor
  • 2020/07, Hiroshima University, Office of Research and Academia-Government-Community Collaboration, Associate Professor

Educational Backgrounds

  • Hiroshima University, Faculty of Medicine, Japan, 1995/04, 2002/03
  • Hiroshima University Graduate School of Biomedical & Health Sciences, Department of Cardiovascular Medicine, Division of Medicine, Biomedical Sciences Major, Japan, 2009/04, 2013/03

Academic Degrees

  • Hiroshima University

Educational Activity

Course in Charge

  1. 2020, Graduate Education (Master's Program) , First Semester, Lecture on Biodesign A1
  2. 2020, Graduate Education (Master's Program) , Second Semester, Lecture on Biodesign A2
  3. 2020, Graduate Education (Master's Program) , First Semester, Lecture on Biodesign B1
  4. 2020, Graduate Education (Master's Program) , Second Semester, Lecture on Biodesign B2
  5. 2020, Graduate Education (Master's Program) , Second Semester, Seminar on Biodesign 1
  6. 2020, Graduate Education (Master's Program) , Second Semester, Seminar on Biodesign 2
  7. 2020, Graduate Education (Master's Program) , Year, Advanced Seminar on Biodesign

Research Activities

Academic Papers

  1. Young Investigator's Award 2020, Transactions of the Japanese Society for Medical and Biological Engineering (JSMBE), 58(4, 5), 188-191, 202009
  2. Lessons learned on frugal innovation from India Biodesign, Medical Globe, 105(June), 7-8, 2019
  3. Fujii T, Kunimoto Y, Kisaka T, Gupta S, Yazama H, Kuya J, Fujiwara K, Takeuchi H. Three Dimensional Motion Analysis of Hand Tremors During Endoscopic Ear Surgery, Yonago Acta Medica 2019;62:109–114
  4. Kisaka T, Stringer WW, Koike A, Agostoni P, Wasserman K. Mechanisms that Modulate Peripheral Oxygen Delivery During Exercise in Heart Failure. Ann Am Thorac Soc. 2017;14:S40-47.
  5. Kisaka T, Dumitrescu D, Rossiter HB, Sietsema KE. Giants in Chest Medicine Karlman Wasserman, MD, PhD, FCCP. Chest. 2017;151(6):1209-1212.
  6. Kisaka T. Reporting from Abroad Laboratory: Respiratory & Critical Care Physiology & Medicine, Harbor-UCLA Medical Center [in Japanese], Japanese Journal of Circulation Research, 39(2), 67-68, 2016
  7. Wasserman K, Kisaka T, Luehrs RE, Bates ML, Kumar VH, Lopez-Barneo J, Zuo L, Zhou T, Ni L, Brain J, Banzett R, Chamoun N. Commentaries on Viewpoint: Why do some patients stop breathing after taking narcotics? Ventilatory chemosensitivity as a predictor of opioid-induced respiratory depression. J Appl Physiol (1985). 2015;119(4):423-5.
  8. Kisaka T, Cox TA, Dumitrescu D, Wasserman K. CO2 Pulse and Acid-Base Status During Increasing Work Rate Exercise in Health and Disease. Respir Physiol Neurobiol. 2015;218:46-56.
  9. Kisaka T, Rossiter HB, Wasserman K, Kihara Y. Exercise Oscillatory Ventilation: Ventilation- Perfusion Abnormality in Heart Failure. Int J Cardiol. 2015;185:55.
  10. Tomita Y, Kasai T, Kisaka T, Rossiter HB, Kihara Y, Wasserman K, Daida H. Altered Breathing Syndrome in Heart Failure: Newer Insights and Treatment Options. Curr Heart Fail Rep. 2015; 12(2):158-65.
  11. Sasaki N, Ozono R, Edahiro Y, Okita T, Teramen K, Kisaka T, Fujiwara S, Kihara Y. Short-term blood pressure variability in hypertensive patients with obstructive sleep apnea syndrome. Sleep Biol. Rhythms. 2015; 13:117-26.
  12. Kinoshita H, Dohi Y, Sada Y, Kisaka T, Kitagawa T, Hidaka T, Yamamoto H, Kihara Y. Exercise oscillatory ventilation (EOV) predicts future adverse events of non-ischemic heart failure. [in Japanese], Shinzo, 46(11), 1534-1537, 2014
  13. Kisaka T, Sada Y, Takeuchi N, Mizukawa M, Oda N, Kimura H, Kihara Y. Cooperation between Heart Failure Center of Hiroshima University Hospital and a regional medical facility: Option for an end-of-life heart failure patient receiving palliative care. J Cardiol Cases. 2014; 9(2):75-79.
  14. Matsuki R, Kisaka T, Ozono R, Kimura H, Kihara Y. Characteristics of patients with severe heart failure exhibiting exercise oscillatory ventilation. Clin Exp Hypertens. 2013;35(4):267-72.
  15. Kisaka T, Kihara Y. Role of the Renin-Angiotensin-Aldosterone System in Left Ventricular Remodeling. Fluid management renaissance. 2013; 3(4), 356-361. [in Japanese]
  16. Kisaka T, Ozono R, Ishida T, Higashi Y, Oshima T, Kihara Y. Association of Elevated Plasma Aldosterone to Renin Ratio with Future Cardiovascular Events in Patients with Essential Hypertension. J Hypertens. 2012, 30:2322–2330
  17. Sairaku A, Nakano Y, Eno S, Hondo T, Matsuda K, Kisaka T, Kihara Y. Platelet function measured using a whole blood aggregometer can predict bleeding events. J Atheroscler Thromb. 2011;18(1):16-23.
  18. Sairaku A, Eno S, Hondo T, Teragawa H, Nakano Y, Matsuda K, Kisaka T, Kihara Y. Head-to-head comparison of the cardio-ankle vascular index between patients with acute coronary syndrome and stable angina pectoris. Hypertens Res. 2010;33(11):1162-6.
  19. Okuhara K, Kisaka T, Ozono R, Kurisu S, Inoue I, Soga J, Yano Y, Oshima T, Kihara Y, Yoshizumi M. Change in bilirubin level following acute myocardial infarction is an index for heme oxygenase activation. South Med J. 2010;103(9):876-81.
  20. Kisaka T, Kihara Y. Treatment of Hypertension in Patients 80 Years of Age or Older. Renin Academy Japan Journal. vol.4, 25(17-18):22, 2010. [in Japanese]
  21. Kisaka T, Eno S, Hondo T, Matsuda K, Sairaku A, Tominaga K. Aspiration, balloon-dilatation, aspiration and stent (ABA-STENT) therapy. Jpn J cardiovasc Cathet Ther 8(1): 37-42, 2008. [in Japanese]
  22. Kurisu S, Inoue I, Kawagoe T, Ishihara M, Shimatani Y, Mitsuba N, Hata T, Nakama Y, Kijima Y, Kisaka T. Acute pericarditis unmasks ST-segment elevation in asymptomatic Brugada syndrome. Pacing Clin Electrophysiol. 2006;29(2):201-3.
  23. Kurisu S, Inoue I, Kawagoe T, Ishihara M, Shimatani Y, Mitsuba N, Hata T, Nakama Y, Kijima Y, Kisaka T. Documentation of acute increase in ventricular capture threshold after direct current cardioversion with AutoCapture threshold record. Pacing Clin Electrophysiol. 2005;28(9):1009-10.
  24. Kurisu S, Inoue I, Kawagoe T, Ishihara M, Shimatani Y, Kisaka T, Kijima Y. Takotsubo-like transient biventricular dysfunction with pressure gradients. Intern Med. 2005;44(7):727-32.
  25. Ishihara M, Inoue I, Kawagoe T, Shimatani Y, Kurisu S, Hata T, Mitsuba N, Kisaka T. Impact of prodromal angina pectoris and white blood cell count on outcome of patients with acute myocardial infarction. Int J Cardiol. 2005;103(2):150-5.
  26. Kurisu S, Inoue I, Kawagoe T, Ishihara M, Shimatani Y, Mitsuba N, Hata T, Nakama Y, Kisaka T, Kijima Y. Temporary overdriving pacing as an adjunct to antiarrhythmic drug therapy for electrical storm in acute myocardial infarction. Circ J. 2005;69(5):613-6.
  27. Kurisu S, Inoue I, Kawagoe T, Ishihara M, Shimatani Y, Mitsuba N, Kisaka T, Kijima Y. Spontaneous anterograde flow of the infarct artery preserves myocardial perfusion and fatty acid metabolism in patients with anterior acute myocardial infarction. Circ J. 2005;69(4):427-31.
  28. Ishihara M, Inoue I, Kawagoe T, Shimatani Y, Kurisu S, Kisaka T, Kijima Y. Comparison of the cardioprotective effect of prodromal angina pectoris and collateral circulation in patients with a first anterior wall acute myocardial infarction. Am J Cardiol. 2005;95(5):622-5.
  29. Kurisu S, Inoue I, Kawagoe T, Ishihara M, Shimatani Y, Mitsuba N, Kisaka T, Kijima Y. Aspiration thrombectomy for acute myocardial infarction resulting from the sequential occlusions of two major coronary arteries in a short time. Intern Med. 2004;43(12):1166-70.
  30. Kurisu S, Inoue I, Kawagoe T, Ishihara M, Shimatani Y, Mitsuba N, Hata T, Nakama Y, Kisaka T, Kijima Y. Acute myocardial infarction associated with myocardial bridging in a young adult. Intern Med. 2004;43(12):1157-61.
  31. Kurisu S, Inoue I, Kawagoe T, Ishihara M, Shimatani Y, Mitsuba N, Hata T, Nakama Y, Kisaka T, Kijima Y. Impact of the magnitude of the initial ST-segment elevation on left ventricular function in patients with anterior acute myocardial infarction. Circ J. 2004;68(10):903-8.

Publications such as books

  1. 2016, Principles of Exercise Testing and Interpretation, 5th Edition, Japanese translation, NPO Japan Heart Club, Textbook, Joint Translation, 日本語, 978-4-9907358-1-4, 544
  2. 2014, Current Treatments for Cardiovascular Diseases, Nanzando, Scholarly Book, Joint work, 日本語/Japanese, 446-450
  3. 2011, Medical treatment of heart failure for family doctors and general practitioners, Nanzando, Scholarly Book, Joint work, 日本語/Japanese

Invited Lecture, Oral Presentation, Poster Presentation

  1. Experience in India Biodesign, Kisaka T, AMED Online Seminar, 2020/10/16, With Invitation, Japanese, Japan Agency for Medical Research and Development (AMED), Tokyo
  2. Minimally Invasive Positive Pressure Drainage(MIPPD), Kisaka T, Ishikita N, The 20th Scientific Meeting of the Japanese Society of Anti-Aging Medicine (JAAM2020), 2020/09/25, Without Invitation, Japanese, Hamamatsucho Convention Hall & Hybrid Studio, Tokyo
  3. Novel Medical Device Development, Sakurai J; Yasuda T; Suzuki T; Anai H; Ueki S; Kisaka T, et al., AMED Symposium for Medical Device Development, 2020/09/18, With Invitation, Japanese, Hokkaido
  4. Learnings from India Biodesign: Hiroshima Biodesign Initiatives, Kisaka T, 2020/09/17, With Invitation, Japanese
  5. Hiroshima Biodesign Initiatives: International medical device development with AMED support and career path for cardiologists, Kisaka T., 2020/09/12, With Invitation, Japanese, Tiyoda, Tokyo
  6. Learnings from India Biodesign: Frugal Innovation, Kisaka T, AMED Online Seminar, 2020/08/21, With Invitation, Japanese, Japan Agency for Medical Research and Development (AMED), Tokyo
  7. Learnings from India Biodesign: Hiroshima University Biodesign (HUB) for Frugal Innovation, Kisaka T., 2020/05/26, With Invitation, Japanese
  8. About practical application support project of 3D printable ventilator model ~ Successful operation test in space transmission and weightless environment ~, Kisaka T., 2020/05/25, With Invitation, Japanese
  9. About practical application support project of 3D printable ventilator model ~ Successful operation test in space transmission and weightless environment ~, Kisaka T., Matsuura Y., 2020/03/27, Without Invitation, Japanese, Hiroshima Univ.
  10. Japan Medical Association Biodesign Workshop-2019, Kisaka T., Japan Medical Association Biodesign Doctor-led Medical Device Development Seminar, 2020/01/26, With Invitation, Japanese, Biodesign Japan
  11. Enhancing international competitiveness by developing universal medical devices, Kisaka T., Hiroshima Medical Industry Study Conference, 2020/01/23, With Invitation, Japanese
  12. Development of new medical devices by Indian biodesign style ~ Commercialization from needs search~, Kisaka T., 2020/01/14, With Invitation, Japanese, Tokyo Univ.
  13. Ideal anesthesia device: "Vapoject" compact, easy, and low cost solution by STONY X Hiroshima Biodesign, Ishikita N, Kisaka T, Deloite Tomatsu Pitch/BRAVE x INDIA, 2019/12/16, With Invitation, English, Deloite Tomatsu, Bengaluru/Hyderabad, India
  14. Development of Novel Medical Devices: Learnings from India Biodesign, Kisaka T, Capital Equipment & Biodesign ~ Application of biodesign to product development methods for diagnostic imaging medical device ~, 2019/11/19, With Invitation, Japanese, CANON MEDICAL SYSTEMS CORPORATION, Nasushiobara, Tokyo
  15. Hiroshima Biodesign, Kisaka T; Matsuura Y; Sako H, The 13th MedTech Summit, 2019/12/07, With Invitation, English, Department of Biotechnology (DBT), Government of India, jointly at AIIMS and IIT Delhi, New Delhi, India
  16. How to Foster Players for Medical Device Development, Yasuda T; Nakanishi T; Burnett D; Kisaka T; Ito T; Yamamoto A; Yoshida T, Japan-US 6th Annual Medtech & Healthtech Innovation Forum, 2019/11/08, With Invitation, English, US-Japan Medtech Frontiers; Foundation for Biomedical Research and Innovation at Kobe; Kobe City Government; Kobe University, Kobe, Japan
  17. Mechanical Assistance During Unloaded Pedaling Improves the Dynamic Range of the Metabolic Response in Obesity, Tomohiko Kisaka, Isao Mizukura, Tolulope Popoola, William Stringer, Kathy Sietsema, 3rd HITACHI Forum "Novel MedTech Development for Exercise Capacity", 2019/10/24, Without Invitation, Japanese, Tokyo, Japan
  18. A decade of learnings in med-tech Innovation, T Kisaka, Y Matsuura, Dr. Avijit Bansal, Tokyo Metropolitan Govt HUB Org Medtech Seminar, 2019/10/21, Without Invitation, Japanese, Tokyo Metropolitan Government, Tokyo, Japan
  19. Hiroshima University Biodesign (HUB) promoting frugal innovation for needs-driven medical devices, Kisaka T, The 23rd Annual Scientific Meeting of the Japanese Heart Failure Society, 2019/10/06, With Invitation, Japanese, Hiroshima, Japan, preprint
  20. Hiroshima Biodesign Program Summary, Kisaka T, BME-IDEA APAC Summit, 2019/07/30, With Invitation, English, BioMedical Engineering: Innovation, Design, and Entrepreneurship Alliance, Tokyo
  21. Recent Development of Novel Medical Devices and Perspective on Indo-Japan Collaboration in Progress, Kisaka T, The 9th Toyohashi Live Demonstration Course, 2019/06/21, With Invitation, Japanese, Tokai Live, Toyohashi Heart Center, Aichi, Japan
  22. Mechanical Assistance During Unloaded Pedaling Improves the Dynamic Range of the Metabolic Response in Obesity, Tolulope Popoola, William Stringer, Tomohiko Kisaka, Kathy Sietsema, American College of Sports Medicine (ACSM) 2019 Annual Meeting, 2019/05/30, Without Invitation, English, ACSM, Orlando, FL
  23. Hiroshima University Biodesign (HUB), Kisaka T, Closed Morning Session, organized by JETRO India, 14th CII-EXIM Bank Conclave on India Africa Project Partnership, 2019/03/18, With Invitation, English, Confederation of Indian Industry, Export-Import Bank of India, the Ministry of External Affairs and the Ministry of Commerce & Industry, Government of India, New Delhi, Through the mutual productive collaboration between India and Japan in medical device development, we envision the future involves bringing our frugal innovation globally for the implication benefitting people in global partner counties in Africa.
  24. Learning from Dr. Wasserman, Harbor-UCLA Medical Center, Kisaka T, The 5th Tokyo Cardiac Rehabilitation Seminar, 2019/02/02, With Invitation, Japanese, Mitsubishi Electric Engineering Co., Ltd., Tokyo
  25. Hiroshima Biodesign, Kisaka T, The 12th MedTech Summit, 2018/12/08, With Invitation, English, Department of Biotechnology (DBT), Government of India, jointly at AIIMS and IIT Delhi, New Delhi
  26. Hiroshima Biodesign, Kisaka T, Health Tech 2018, 2018/03/08, With Invitation, English, The Bengal Chamber, Japan External Trade Organization(JETRO) India, MEDICA Hospitals, Kolkata, West Bengal, India
  27. International Collaboration in Healthcare: Experiences in US, Japan and India & the way forward, Kisaka T, Seminar on Multi-disciplinary International Collaborations for developing solutions in Healthcare, 2017/06/30, With Invitation, English, Nichi-In Centre for Regenerative Medicine, Loyola-ICAM Collage of Engineering and Technology, Chennai, India., other
  28. Respiratory Physiology in Cardiac Rehabilitation: Clinical Applications of Cardiopulmonary Exercise Testing, Kisaka T, Hakimi M, Sietsema KE, Rossiter HB, Kihara Y, Wasserman K, SICE Life Engineering Symposium 2016, 2016/11/03, With Invitation, Japanese, The Society of Instrument & Control Engineering, Osaka, Japan
  29. Characterizing Functional Capacity in Obesity, Project Meeting, 2016/08/28, With Invitation, Japanese, Mitsubishi Electric Engineering Co. Ltd., Aichi, Japan

Awards

  1. 2016, Visiting Scholarship Program Meritorious Completion Medal gifted by Dr. Karlman Wasserman, Harbor-UCLA Medical Center, University of California, Los Angeles
  2. 2014, New Investigator Award for Japanese Fellow, American Heart Association, High Blood Pressure Research Congress
  3. 2012, Excellent Student Scholarship Award, Hiroshima Univ Graduate School of Biomedical & Health Sciences

Patented

  1. Patent, JP2018134294, 2018/08/30, KINESITHERAPY APPARATUS AND ANAEROBIC THRESHOLD IDENTIFYING METHOD

External Funds

Acceptance Results of Competitive Funds

  1. Japan Agency for Medical Research and Development (AMED) 2020, 3D-printable ventilator developed by National Hospital Organization (COVIDVENT), 2020/05/13, 2021/03/31
  2. Research grant from Fukuda Health Foundation, Tokyo, Japan, 2013
  3. Research Grant Award, Tsuchiya Memorial Foundation, 2012

Social Activities

History as Committee Members

  1. in silico committee, 2020/11, Japanese Society for Medical and Biological Engineering
  2. Councilor, 2020/07, 2022/12, Japanese Society of Anti-Aging Medicine (JAAM)
  3. Young Investigator Award Committee Member, 2019, 2020, Japanese Society for Medical and Biological Engineering
  4. Medtech Collaboration Lead Coordinator, 2018/10, 2021/03, Hiroshima Prefectural Government
  5. Adjunct Faculty, 2019, Centre for Biodmedical Engineering, Indian Institute of technology, Delhi
  6. Part-time lecturer, 2019/09, 2021/01, The University of Tokyo, College of Arts and Sciences/Graduate School of Arts and Sciences
  7. Part-time lecturer, 2019/09, 2021/01, The University of Tokyo, Integrated Sciences
  8. Biodesign Seminar, 2019/10, 2020/01, Japan Biodesign Association
  9. Biodesigner Seminar Lecturer, 2019/06, 2020/03, Japan Biodesign
  10. Program of Start-up Incubation from Core Research (SCORE), 2018, 2019, Japan Science and Technology Agency
  11. RESPECT Study Investigators, Hiroshima Prefecture, 2010, 2018

History as Peer Reviews of Academic Papers

  1. 2019, J Stem Cells, Editor, Associate Editor
  2. 2017, J Physiol Sci, Others, reviewer
  3. 2015, Am J Med Sci, Others, reviewer
  4. Am J Physiol Regul Integr Comp Physiol, Others, reviewer
  5. J Appl Physiol, Others, reviewer
  6. J Atheroscler Thromb, Others, reviewer
  7. South Med J, Others, reviewer