MIYUKI TAKASU

Last Updated :2020/12/01

Affiliations, Positions
Hiroshima University Hospital
E-mail
mtakasuhiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Doctor of Philosophy in Medical Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Radiation science

Research Keywords

  • myeloma

Affiliated Academic Societies

  • Japan Society for CNS Computed Imaging
  • JAPANESE SOCIETY OF NUCLEAR MEDICINE, 2017
  • Japanese Society of Myeloma
  • The Japanese Society for Bone and Mineral Reserch
  • International Society for Magnetic Resonance in Medicine
  • Radiological Society of North America

Educational Activity

Course in Charge

  1. 2020, Undergraduate Education, Year, Clinical diagnosis and treatment II
  2. 2020, Undergraduate Education, Intensive, Symptomatology, Diagnosis and Treatment

Research Activities

Academic Papers

  1. Assessment of early treatment response on MRI in multiple myeloma: Comparative study of whole-body diffusion-weighted and lumbar spinal MRI, PLOS ONE, 15(2), 20200227
  2. How to Improve the Conspicuity of Breast Tumors on Computed High b-value Diffusion-weighted Imaging., Magn Reson Med Sci., 18(2), 119-125, 20190410
  3. Differentiation of Myelodysplastic Syndrome from Aplastic Anemia Using Conventional Multiparametric MRI and Machine Learning, archive.rsna.org/2019/19008752.html
  4. Assessment of early treatment response by multiparametric whole-body MRI as a 1-step approach to prediction of overall response rate in patients with multiple myeloma, Proceedings of 2018 annual meeting of ISMRM
  5. Assessment of Early Treatment Response by MRI in Multiple Myeloma: Comparative Study of Whole-Body MRI and Lumbar Spinal MRI, archive.rsna.org/2018/18009145.html
  6. Utility of CT Metal Artifact Reduction Algorithms for Intervertebral Devices: Experimental Study in Ex Vivo Bovine Coccyx Using Micro-CT as the Reference Standard, archive.rsna.org/2018/18009110.html
  7. Preliminary Investigation: Gaussian and Non-Gaussian Measurements of Water Diffusion in Diagnostic Differentiation of Focal Lesions of Malignant Spinal Bone Tumors, Proceedings of 2017 annual meeting of ISMRM
  8. A Longitudinal Study of the Prediction of Pathologic Spinal Fractures in Multiple Myeloma with Trabecular Microarchitecture and CT-Based Finite Element Analyses, J Musculoskelet Disord Treat, 2(4), 19
  9. High spatial resolution magnetic resonance imaging of hip joint using three-dimensional (3D) sequences for evaluating acetabular labral injury, femoroacetabular impingement and postoperative muscle atrophy, archive.rsna.org/2016/16000764.html
  10. Effect of iterative reconstruction algorithms on measurement of trabecular bone microstructure with clinical MDCT: a cadaver study, S310-S310
  11. Effect of Autologous Stem Cell Transplant on Bone Mineral Density and Bone Strength in Patients with Multiple Myeloma, archive.rsna.org/2016/16044287.html
  12. Iterative Decomposition of Water and Fat with Echo Asymmetry and Least-Squares Estimation (IDEAL) Magnetic Resonance Imaging as a Biomarker for Symptomatic Multiple Myeloma, PLOS ONE, 10(2), FEB 23 2015
  13. Trabecular bone changes in the spine after transarterial chemoembolization therapy for hepatocellular carcinoma., Clin Calcium, 25(11), 1659-1666
  14. Clinical Application of Gamma Distribution Model for Spinal Lesions: Initial Clinical Results, Proc. Intl. Soc. Mag. Reson. Med. 23 (2015)
  15. Vertebral Bone Marrow Fat Content Measured by MRI Associated with Lower Bone Mineral Density: A Human Cadaver Study, Proc. Intl. Soc. Mag. Reson. Med. 23 (2015)
  16. A longitudinal study of predicting pathologic spine fractures in multiple myeloma with CT-based finite element analyses, S325-S326
  17. Vertebral Bone Marrow Fat Content Measured by MRI is Associated with Bone Mineral Density: A Cadaveric Study Using Micro-CT, archive.rsna.org/2015/15047476.html
  18. Effect of Iterative Reconstruction Algorithms on Measurement of Trabecular Bone Microstructure with Clinical MDCT: A Cadaver Study Using Micro-CT as the Reference Standard, archive.rsna.org/2015/15009338.html
  19. Magnetic Resonance Evaluation of Multiple Myeloma at 3.0 Tesla: How Do Bone Marrow Plasma Cell Percentage and Selection of Protocols Affect Lesion Conspicuity?, PLOS ONE, 9(1), JAN 28 2014
  20. Multidetector Computed Tomography-Based Microstructural Analysis Reveals Reduced Bone Mineral Content and Trabecular Bone Changes in the Lumbar Spine after Transarterial Chemoembolization Therapy for Hepatocellular Carcinoma, PLOS ONE, 9(10), OCT 16 2014
  21. A Longitudinal Computed Tomography Study of Lenalidomide and Bortezomib Treatment for Multiple Myeloma: Trabecular Microarchitecture and Biomechanics Assessed Using Multidetector Computed Tomography, CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 14(6), 485-492, DEC 2014
  22. Vertebral Fracture Risk of Multiple Myeloma Assessed by a CT-based Finite Element and Trabecular Structure Analysis, CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 14(1), 12-13, FEB 2014
  23. Pituitary Volumes and Functions in Children with Growth Hormone Deficiency: Volumetric Magnetic Resonance Findings, Journal of Endocrinology and Diabetes Mellitus, 2(1), 39-44
  24. Magnetic Resonance Evaluation of Multiple Myeloma at 3.0 Tesla: How Do Bone Marrow Plasma Cell Percentage and Selection of Protocols Affect Lesion Conspicuity?, Proc. Intl. Soc. Mag. Reson. Med. 22 (2014), 1241-1241
  25. Interrelationships Between 3T-MRI-, 64-Section-MDCT-, and Micro-CT-Derived Trabecular Bone Structure Parameters: A Study in Cadavers, Proc. Intl. Soc. Mag. Reson. Med. 22 (2014), 1240-1240
  26. CT-based finite element modeling and microstructural analysis detect reduced bone mineral content and bone strength in the spine after TACE, S399-S399
  27. Multiple antiplatelet therapy contributes to the reversible high signal spots on diffusion-weighted imaging in elective coiling of unruptured cerebral aneurysm, NEURORADIOLOGY, 55(4), 449-457, MAR 2013
  28. Ocular Volumetry Using Fast High-Resolution MRI during Visual Fixation, AMERICAN JOURNAL OF NEURORADIOLOGY, 34(4), 870-876, APR 2013
  29. Iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) imaging of multiple myeloma: initial clinical efficiency results, EUROPEAN RADIOLOGY, 22(5), 1114-1121, MAY 2012
  30. Effect of age on the fractional anisotropy (FA) value of peripheral nerves and clinical significance of the age-corrected FA value for evaluating polyneuropathies, NEURORADIOLOGY, 54(8), 815-821, AUG 2012
  31. Iterative Decomposition of Water and Fat with Echo Asymmetry and Least-Squares Estimation (IDEAL) Imaging of Multiple Myeloma: Discriminant Analysis for Differentiation of Tumor Staging, Proc. Intl. Soc. Mag. Reson. Med. 20 (2012), 3047-3047, 20120507
  32. The usefulness of ADC value evaluation for differentiating pancreatic malignant lymphoma from other pancreatic lesions : A case report, The Journal of the Hiroshima Medical Association, 65(5), 414-419
  33. Diffusion tensor imaging of peripheral nerve in patients with chronic inflammatory demyelinating polyradiculoneuropathy: a feasibility study, NEURORADIOLOGY, 53(12), 955-960, DEC 2011
  34. Evaluation of lumber nerve root compression using thin-slice thickness coronal magnetic resonance imaging: three-dimensional fat-suppressed multi-shot balanced non-steady-state free precession versus three-dimensional T1-weighted spoiled gradient-recalled echo, JAPANESE JOURNAL OF RADIOLOGY, 29(9), 623-629, NOV 2011
  35. Multiple Myeloma: Microstructural Analysis of Lumbar Trabecular Bones in Patients without Visible Bone Lesions-Preliminary Results, RADIOLOGY, 260(2), 472-479, AUG 2011
  36. Gadolinium enhancement of cauda equina after combined spinal-epidural anaesthesia., Br J Radiol, Br J Radiol(993), e192-e194
  37. Pituitary volumes and functions in children with growth hormone deficiency: Volumetric magnetic resonance data, Proc. Intl. Soc. Mag. Reson. Med. 18 (2010), 4404-4404, 20100506
  38. Evaluation of skeletal muscle with diffusion tensor imaging, The Journal of the Hiroshima Medical Association, 63(7), 503-504
  39. Usefulness of drip infusion cholangiography-computed tomography in evaluating aberrant hepatic and accessory cystic ducts before and after cholecystectomy: three cases report, The Journal of the Hiroshima Medical Association, 63(3), 185-189
  40. Trabecular bone analysis of lumbar spine in patients with multiple myeloma by multidetector CT, The Japanese Journal of Clinical Hematology, 51(9), 1053-1053
  41. Asymptomatic air embolism after computed tomography-guided lung needle marking., Journal of Thoracic oncology, 20090701
  42. A case of lower limbas neuralgia after spinal anesthesia receiving hyperbaric bupivacaine, Anesthesia and Resuscitation, 45(2), 35-37
  43. A case of matrix-producing carcinoma, Japanese Journal of Clinical Radiology, 53(3), 431-436
  44. A case of MELAS: hyperperfused lesions detected by non-invasive perfusion-weighted MR imaging., Magn Reson Med Sci, 1(1), 50-53
  45. Evaluation of Non-Invasive Perfusion-Weighted MRI, Proc. Intl. Soc. Mag. Reson. Med. 8 (2000), 716-716, 20000406
  46. Clinical Evaluation of Non-invasive Perfusion-weighted MRI, Medical Journal of Hiroshima University, 48(6), 375-389

Invited Lecture, Oral Presentation, Poster Presentation

  1. External validation of a machine learning algorithm for differentiating between myelodysplastic syndromes and aplastic anemia, Miyuki Takasu, Takashi Abe, Shogo Maeda, Yasutaka Baba, Yuji Akiyama, Yuji Takahashi, Hideaki Kakizawa, Kazuo Awai, 2020 ISMRM & SMRT Annual Conference & Exhibition, 2020/08, Without Invitation, English, ISMRM
  2. Differentiation of Spinal Lesions Using Monoexponential, Biexponential, and Gamma Distribution Diffusion-Weighted MR Imaging: Initial Clinical Results, Takasu M, Akiyama Y, Kaichi Y, Tani C, Oshio K, Awai K, International Society for Magnetic Resonance in Medicine 24th Joint Annual Meeting, 2016/05/07, Without Invitation, English, Singapore
  3. Effect of autologous stem cell transplant on bone mineral density and bone strength in patients with multiple myeloma, Takasu M, Fujioka C, Takauchi K, Baba Y, Kaichi Y, Kiguchi M, Tani C, Awai K, 102th Annual Meeting of RSNA, 2016/12/03, Without Invitation, English
  4. High spatial resolution magnetic resonance imaging of hip joint using three-dimensional (3D) sequences for evaluating acetabular labral injury, femoroacetabular impingement and postoperative muscle atrophy, Tanitame K, Sueoka T, Honda Y, Takahashi Y, Takasu M, Fukumoto W, Iida M, Awai K, 102th Annual Meeting of RSNA, 2016/12/02, Without Invitation, English
  5. Assessment of early treatment response by multiparametric whole-body MRI as a 1-step approach to prediction of overall response rate in patients with multiple myeloma, Miyuki Takasu, Takayuki Tamura, Yuji Akiyama, Yoko Kaichi, Shota Kondo, Chihiro Tani, Kazuo Awai, International Society for Magnetic Resonance in Medicine 27th Joint Annual Meeting, 2018/06/19, Without Invitation, English, International Society for Magnetic Resonance in Medicine, Paris
  6. Does chemical shift imaging offer a biomarker for the diagnosis and assessment of disease severity in multiple myeloma?, Miyuki Takasu, International Society for Magnetic Resonance in Medicine 27th Joint Annual Meeting, 2018/06/18, Without Invitation, English, International Society for Magnetic Resonance in Medicine, Paris
  7. Preliminary Investigation: Gaussian and Non-Gaussian Measurements of Water Diffusion in Diagnostic Differentiation of Focal Lesions of Malignant Spinal Bone Tumors, Takasu, Miyuki Akiyama, Yuji Yokomachi, Kazushi Kaichi, Yoko Tani, Chihiro Oshio, Koichi Awai, Kazuo, International Society for Magnetic Resonance in Medicine 25th Joint Annual Meeting, 2017/04/26, Without Invitation, English, Honolulu
  8. Differentiation of myelodysplastic syndrome from aplastic anemia using conventional multiparametric MRI and Machine Learning, Miyuki Takasu, Takashi Abe, Yasutaka Baba, Takakazu Kawase, Shogo Maeda, Kazuo Awai, Akira Nishikori, Tatsuo Ichinohe, Radiological Society of North America 105th Scientific Assembly and Annual Meeting, 2019/12/01, Without Invitation, English, Radiological Society of North America, Chicago
  9. Quantitative comparison of conventional and synthetic MRI for cortical and trabecular bone architecture: ex vivo study of bovine coccyx, Miyuki Takasu, Yuji Akiyama, Akira Nishikori, Yoko Kaichi, Shogo Maeda, Kazuo Awai, International Society for Magnetic Resonance in Medicine 27th Annual Meeting & Exhibition, 2019/05/13, Without Invitation, English, International Society for Magnetic Resonance in Medicine, Montreal
  10. Utility of CT metal artifact reduction algorithms for intervertebral devices: experimental study in ex vivo bovine coccyx using micro-CT as the reference standard, Miyuki Takasu, Kazuyoshi Nakanishi, Chikako Fujioka, Shota Kondo, Tomoyo Fuji, Chihiro Tani, Masao Kiguchi, Kazuo Awai, Radiological Society of North America 104th Scientific Assembly and Annual Meeting, 2018/11/26, Without Invitation, English, Radiological Society of North America, Chicago
  11. Clinical Application of Gamma Distribution Model for Spinal Lesions: Initial Clinical Results, Takasu, Miyuki Oshio, Koichi Akiyama, Yuji Akita, Ryuji Yokomachi, Kazushi Kaichi, Yoko Date, Shuji Awai, Kazuo, International Society for Magnetic Resonance in Medicine 23th Annual Meeting, 2015/06/01, Without Invitation, English, International Society for Magnetic Resonance in Medicine, Tronto
  12. Vertebral Bone Marrow Fat Content Measured by MRI Associated with Lower Bone Mineral Density: A Human Cadaver Study, Takasu, Miyuki Akiyama, Yuji Akita, Ryuji Yokomachi, Kazushi Kaichi, Yoko Date, Shuji Honda, Masatoshi Awai, Kazuo, International Society for Magnetic Resonance in Medicine 23th Annual Meeting, 2015/06/01, Without Invitation, English, Tronto
  13. Interrelationships Between 3T-MRI-, 64-Section-MDCT-, and Micro-CT-Derived Trabecular Bone Structure Parameters: A Study in Cadavers, Miyuki Takasu, Yoko Kaichi, Chihiro Tani, Shuji Date, Yuji Akiyama, Nobuhito Nango, and Kazuo Awai, International Society for Magnetic Resonance in Medicine Joint Annual Meeting ISMRM-ESMRMB 2014, 2014/05/12, Without Invitation, English, International Society for Magnetic Resonance in Medicine, Milan
  14. Magnetic Resonance Evaluation of Multiple Myeloma at 3.0 Tesla: How Do Bone Marrow Plasma Cell Percentage and Selection of Protocols Affect Lesion Conspicuity?, Miyuki Takasu, Yoko Kaichi, Chihiro Tani, Shuji Date, Yuji Akiyama, Yoshiaki Kuroda, Akira Sakai, and Kazuo Awai, International Society for Magnetic Resonance in Medicine Joint Annual Meeting ISMRM-ESMRMB 2014, 2014/05/12, Without Invitation, English
  15. Effect of Iterative Reconstruction Algorithms on Measurement of Trabecular Bone Microstructure with Clinical MDCT: A Cadaver Study Using Micro-CT as the Reference Standard, Miyuki Takasu, MD | Chikako Fujioka, RT | Masao Kiguchi, RT | Chihiro Tani, MD | Yoko Kaichi | Kazuo Awai, MD | Nobuhito Nango, | Masafumi Machida,, Radiological Society of North America 101th Scientific Assembly and Annual Meeting, 2015/12/02, Without Invitation, English, Radiological Society of North America, Chicago
  16. Predicting Pathologic Spine Fracture in Multiple Myeloma Patients Using Trabecular Microarchitecture and CT-based Finite Element Analysis: A Longitudinal Study, Miyuki Takasu, Yoko Kaichi, Chihiro Tani, Shuji Date, Masao Kiguchi, Kazuo Awai, Yoshiaki Kuroda, Akira Sakai, Radiological Society of North America 100th Scientific Assembly and Annual Meeting, 2014/12/05, Without Invitation, English, Radiological Society of North America, Chicago
  17. CT-based finite element modeling and microstructural analysis detect reduced bone mineral content and bone strength in the spine after CT fluoroscopy-guided interventional procedures, Miyuki Takasu, Yuko Nakamur, Daisuke Komoto, Masaki Ishikawa, Masao Kiguchi RT | Kazuo Awai, Shuji Date, Chihiro Tani, Radiological Society of North America 99th Scientific Assembly and Annual Meeting, 2013/12/04, Without Invitation, English, Radiological Society of North America, Chicago
  18. Can IDEAL-MR imaging of multiple myeloma be used as a biomarker for predicting symptomatic myeloma?, Miyuki Takasu, Yoko Kaichi, Miho Ishikawa, Shuji Date, Yuji Akiyama, Kazuo Awai, Yoshiaki Kuroda, Akira Sakai, Radiological Society of North America 99th Scientific Assembly and Annual Meeting, 2013/12/05, Without Invitation, English, Radiological Society of North America, Chicago
  19. Trabecular bone changes and subclinical secondary osteoporosis following gastrectomy detected by multidetector CT, Miyuki Takasu, Yukiko Honda, Shuji Date, Masao Kiguchi, Kenichiro Matsuzaki, Kazuo Awai, Takahisa Suzuki, Kazuaki Tanabe, Radiological Society of North America 99th Scientific Assembly and Annual Meeting, 2013/12/05, Without Invitation, English, Radiological Society of North America, Chicago
  20. A longitudinal CT study of lenalidomide and bortezomib treatment for multiple myeloma: Trabecular microarchitecture and biomechanics assessed by a CT-based finite element model, Miyuki Takasu, Yoko Kaichi, Miho Ishikawa, Shuji Date, Masao Kiguchi, Kazuo Awai, Yoshiaki Kuroda, Akira Sakai, Radiological Society of North America 99th Scientific Assembly and Annual Meeting, 2013/12/06, Without Invitation, English, Radiological Society of North America, Chicago
  21. MR Evaluation of Multiple Myeloma at 3.0 Tesla: How do bone marrow signal intensity and selection of protocols affect lesion conspicuity?, Miyuki Takasu, Yoko Kaichi, Miho Ishikawa, Yuji Akiyama, Shuji Date, Akira Sakai, Yoshiaki Kuroda, Kazuo Awai, International Society for Magnetic Resonance in Medicine 21th Annual Meeting and Exhibition, 2013/04/23, Without Invitation, English, International Society for Magnetic Resonance in Medicine, Saltlake city
  22. Patients with multiple myeloma: finite element analysis using multidetector CT to predict pathological fracture, M. Takasu, T. Higaki, C. Tani, M. Kiguchi, F. Tatsugami, K. Awai, Y. Kuroda, A. Sakai, Radiological Society of North America 98th Scientfic Assembly and Annual Meeting, 2012/11/25, Without Invitation, English, Radiological Society of North America, Chicago
  23. Transient thickening of trabecular bone in patients with multiple myeloma detected by microstructure analysis of lumbar vertebrae using multidetector computed tomography, Miyuki Takasu, Chihiro Tani, Yuko Nakamura, Yukiko Honda, Miho Ishikawa, Shuji Date, Kazuo Awai, Shigeko Sakoda, Mari Matsuda, Hideki Asaoku, Akira Sakai, The 71th Annual Meeting of the Japan Radiological Society, 2012/04/12, Without Invitation, Japanese, Japan Radiological Society, Yokohama
  24. Iterative Decomposition of Water and Fat with Echo Asymmetry and Least-Squares Estimation (IDEAL) Imaging of Multiple Myeloma: Initial Clinical Efficiency Results, M. Takasu, Y. Akiyama, C. Tani, K. Tanitame, A. Sakai, K. Awai, S. Date, T. Kajima, Radiological Society of North America 97th Scientific Assembly and Annual Meeting, 2011/11/27, Without Invitation, English
  25. Transient Thickening of Trabecular Bone in Patients with Multiple Myeloma Detected by Microstructure Analysis of Lumbar Vertebrae Using Multidetector Computed Tomography, M. Takasu, M. Kiguchi, M. Ishikawa, S. Date, A. Sakai, K. Awai, M. Matsuda, H. Asaoku, Radiological Society of North America 97th Scientific Assembly and Annual Meeting, 2011/11/28, Without Invitation, English, Radiological Society of North America, Chicago
  26. Microstructure Analysis of Lumbar Trabecular Bones in Patients with Multiple Myeloma Using Multidetector CT to Detect Subclinical Bone Lesions, M. Takasu, M. Kiguchi, S Date, H Fukuda, A. Sakai , K. Awai, H. Asaoku, A. Tamura, Radiological Society of North America 96th Scientific Assembly and Annual Meeting, 2010/11/30, Without Invitation, English, Radiological Society of North America, Chicago
  27. Pituitary volumes and functions in children with growth hormone deficiency: Volumetric magnetic resonance findings, M. Takasu, C. Tani, M. Ishikawa, K. Tanitame, H. Fukuda, J. Horiguchi, Y. Nishi, S. Okada, and K. Awai, ENDO 2010, 2010/06/19, Without Invitation, English, Endocrine Society, San Diego

External Funds

Acceptance Results of Competitive Funds

  1. 2010/04, 2012/03
  2. Kano-grant, 2010/04, 2011/03
  3. IMF Japan's grants, 2012/04, 2014/03
  4. 2010/04, 2011/03
  5. Grants-in-Aid for Scientific Research, Clinical Evaluation of Non-invasive Perfusion-weighted MRI, 2000/04/01, 2001/03

Social Activities

History as Peer Reviews of Academic Papers

  1. 2020, The Journal of the Hiroshima Medical Association, Editor, 12
  2. 2016, The Journal of the Hiroshima Medical Association, Editor
  3. 2017, The Journal of the Hiroshima Medical Association, Editor
  4. 2018, The Journal of the Hiroshima Medical Association, Editor
  5. 2019, The Journal of the Hiroshima Medical Association, Editor, 12
  6. 2015, The Journal of the Hiroshima Medical Association, Editor
  7. 2014, The Journal of the Hiroshima Medical Association, Editor
  8. 2013, The Journal of the Hiroshima Medical Association, Editor