TOMOAKI HAMANA

Last Updated :2023/02/02

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Dentistry & Oral Health Sciences), Assistant Professor
E-mail
tomoh57hiroshima-u.ac.jp
Other Contact Details
1-2-3,Kasumi,Minami-ku,Hiroshima, Japan
TEL : (+81) FAX : (+81)
Self-introduction
Oral Surgeon Studies on the function of cell adhesion molecules and their regulation in the invasive growth of oral cancer

Basic Information

Major Professional Backgrounds

  • 2004/04/01, 2005/03/31, Hiroshima University Hospital, Clinical Fellow
  • 2005/04/01, 2007/03/31, Clinical Fellow
  • 2007/04/01, 2008/03/31, Chugoku Rosai Hospital, Clinical Fellow
  • 2008/04/01, 2009/03/31, Chugoku Rosai Hospital
  • 2009/04/01, 2010/03/31, Hiroshima University Hospital, Clinical Fellow
  • 2010/04/01, 2012/03/31, Hiroshima University, Graduate School of Biomedical Sciences, Assistant Professor
  • 2012/04/01, 2019/03/31, Hiroshima University, Institute of Biomedical & Health Sciences, Assistant Professor
  • 2019/04/01, Hiroshima University, Graduate School of Biomedical & Health Sciences, Assistant Professor

Educational Backgrounds

  • Hiroshima University, Japan, 2000/04, 2004/03
  • Hiroshima University, Japan, 1994/04, 2000/03

Academic Degrees

  • Doctor of Philosophy in Dental Science, Hiroshima University

Educational Activity

  • [Bachelor Degree Program] School of Dentistry : Program of Dentistry : Dentistry
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Dental Sciences

In Charge of Primary Major Programs

  • Dentistry

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Surgical dentistry

Affiliated Academic Societies

  • Japan Society for Head and Neck Cancer
  • Japanese Society of Oral Oncology
  • Japanese Society of Oral and Maxillofacial Surgeons
  • Japanese Stomatological Society
  • Japanese Cancer Association
  • Asian Association of Oral and Maxillofacial Surgeons
  • Japanese Society of Oral Medicine

Educational Activity

Course in Charge

  1. 2022, Undergraduate Education, 1Term, Oral and Maxillofacial Surgery I
  2. 2022, Undergraduate Education, 2Term, Oral and Maxillofacial Surgery II
  3. 2022, Undergraduate Education, First Semester, Dental Research Practices
  4. 2022, Undergraduate Education, 3Term, Basic Practice of Oral and Maxillofacial Medicine I
  5. 2022, Undergraduate Education, 4Term, Basic Practice of Oral and Maxillofacial Medicine II
  6. 2022, Undergraduate Education, Second Semester, Dental Research Practices
  7. 2022, Undergraduate Education, First Semester, Dental Research Practices
  8. 2022, Undergraduate Education, Academic Year, Clinical Practice (Oral Surgery I)
  9. 2022, Undergraduate Education, First Semester, Clinical Practice in Oral Health Engineering
  10. 2022, Undergraduate Education, Second Semester, Clinical Practice in Oral Health Engineering

Research Activities

Academic Papers

  1. A case of primary neuroendocrine carcinoma of the mandibular gingiva treated using multimodal therapy, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 2022
  2. Nivolumab monotherapy after induction chemotherapy, bioradiotherapy, and cetuximab monotherapy leading to complete remission of locoregional advanced tongue cancer: A case report, Oral Science International, 202201
  3. Four cases of extranodal marginal zone lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma) of salivary gland in the oral cavity, 20210601
  4. Comprehensive Oral Management for Collaborative Medical and Dental Care -Practical Approaches for Oral Care Support Team-, The Journal of Hiroshima University Dental Society, 45(1), 1-6, 20130601
  5. ★, Plasminogen activator/plasmin system suppresses cell-cell adhesion of oral squamous cell carcinoma cells via proteolysis of E-cadherin, INTERNATIONAL JOURNAL OF ONCOLOGY, 27(3), 693-698, 200509
  6. Comparison of the prognosis of bisphosphonate-related osteonecrosis of the jaw caused by oral and intravenous bisphosphonates, INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 44(7), 840-844, 201507
  7. ★, Overexpression of FGF9 in Prostate Epithelial Cells Augments Reactive Stroma Formation and Promotes Prostate Cancer Progression, International Journal of Biological Sciences
  8. ★, Prostate sphere-forming stem cells are derived from the P63-expressing basal compartment, Journal of Biological Chemistry
  9. ★, Type 2 fibroblast growth factor receptor signaling preserves stemness and prevents differentiation of prostate stem cells from the basal compartment, Journal of Biological Chemistry
  10. ★, Induction of a2-antiplasmin inhibits E-cadherin processing mediated by the plasminogen activator/plasmin system,leading to suppression of progression of oral squamous cell carcinoma via upregulation of cell-cell adhesion
  11. Management of an Internal Carotid Artery Injury Caused by a Displaced Titanium Plate With a Combination of Interventional Vascular Radiology and Surgery, JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 76(6), 201806
  12. Suture granulomas developing after the treatment of oral squamous cell carcinoma, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 50, 68-71, 2018
  13. Primary intraosseous carcinoma of mandible associated with elevation of serum carcinoembryonic antigen level, Oral Oncology Extra
  14. Dedifferentiation in adenoid cystic carcinoma of submaxillary gland: A case of report, Oral Oncology Extra
  15. A clinical study of super-elderly patients over 90 years old with oral cancer, J. Jpn. Stomatol. Soc., 68(1), 12-19
  16. Clinical investigation of oral cancer in Adolescent and Young Adult(AYA)generation, 68(1), 20-27
  17. A Clinical Study of Ameloblastoma in Our Department, 52(1), 7-13, 20200601
  18. Clinical investigation of oral cancer in adolescent and young adult generation, ORAL SCIENCE INTERNATIONAL, 18(2), 126-134, 202105
  19. A case of maxillary ameloblastic carcinoma with atypical histology, JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY, 33(5), 536-545, 202109
  20. Lip support prosthesis for the patients after resection of oral floor cancer, 20201201
  21. Nivolumab monotherapy after induction chemotherapy, bioradiotherapy, and cetuximab monotherapy leading to complete remission of locoregional advanced tongue cancer: A case report, ORAL SCIENCE INTERNATIONAL, 19(1), 72-76, 202201

Invited Lecture, Oral Presentation, Poster Presentation

  1. Participation of Plasminogen/plasmin system in the proliferation of oral squamous cell carcinoma cells, 2021/05/13, Without Invitation, Japanese
  2. Plasminogen/plasmin system-mediated proliferation of oral squamous cell carcinoma cells, 2020/11/13, Without Invitation, Japanese
  3. A case of advanced tongue cancer with giant cervical lymph node metastases successfully treated with platinum-based chemotherapy, bio-radiotherapy with cetuximab (Cmab), followed by Cmab and nivolumab monotherapy., 2018/06/09, Without Invitation, Japanese
  4. A case of dentigerous cyst associated with a wisdom tooth in the maxillary sinus, 2018/06/09, Without Invitation, Japanese

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2021, 2023
  2. KAKENHI, 2014, 2016
  3. KAKENHI, Development of gene therapy for oral cancer mediated by Naked DNA of molecule processing E-cadherin, 2012, 2013
  4. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2017, 2019

Social Activities

Organizing Academic Conferences, etc.

  1. 2016/05, 2016/05
  2. 2016/10, 2016/10
  3. 2017/10
  4. 2019/10
  5. 2019/10