NAOTO SHIMIZU
Last Updated :2024/03/04
- Affiliations, Positions
- Graduate School of Integrated Sciences for Life, Assistant Professor
- Web Site
- E-mail
- naotoshiroshima-u.ac.jp
Basic Information
Major Professional Backgrounds
- 2021/04/01, Graduate School of Integrated Sciences for Life, Hiroshima University, Assistant Professor
Academic Degrees
- University of Tsukuba
- Kyoto University
Research Fields
- Biology;Biological Science;Molecular biology
- Biology;Biological Science;Cell biology
- Biology;Basic biology;Genetics / Chromosome dynamics
- Environmental science;Environmental analyses and evaluation;Risk sciences of radiation and chemicals
Research Keywords
- TK6 cells
- DNA damage
- DNA repair
- radiation, anti-cancer drug
- cancer
Affiliated Academic Societies
- The Japanese Environmental Mutagen and Genome Society
- The Japanese Radiation Research Society
Educational Activity
Course in Charge
- 2023, Undergraduate Education, 2Term, Advanced Biology
- 2023, Undergraduate Education, 4Term, Biochemistry A
- 2023, Undergraduate Education, First Semester, Practice for Fundamental Biology I
- 2023, Undergraduate Education, First Semester, Practice for Fundamental Biology III
- 2023, Graduate Education (Master's Program) , 2Term, Topical Seminar in Life Science A
- 2023, Graduate Education (Master's Program) , 4Term, Topical Seminar in Life Science B
- 2023, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar A
- 2023, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar B
- 2023, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar C
- 2023, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar D
- 2023, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar E
Research Activities
Academic Papers
- ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen, Cell Reports, 2023
- XRCC1 counteracts PARP poisons, Olaparib and Talazoparib, and a clinical alkylating agent, Temozolomide, by promoting the removal of trapped PARP1 from broken DNA, Genes to Cells, 20220223
- Repair pathways for radiation DNA damage under normoxic and hypoxic conditions: Assessment with a panel of repair-deficient human TK6 cells, Journal of Radiation Research, 62(6), 999-1004, 20210925
- ★, The MRE11 nuclease promotes homologous recombination not only in DNA double-strand break resection but also in post-resection in human TK6 cells, Genome Instability & Disease, 1, 184-196, 20200630
- Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells, Proceedings of the National Academy of Sciences of the United States of America (PNAS), 117(25), 14412-14420, 20200608
- ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair, PLOS ONE, 12(11), e0188320, 20171117
- ★, Distinct DNA damage spectra induced by ionizing radiation in normoxic and hypoxic cells, Radiation Research, 184(4), 442-448, 20151002
Invited Lecture, Oral Presentation, Poster Presentation
- Repair pathways for radiation DNA damage under normoxic and hypoxic conditions: Assessment with a panel of repair-deficient human TK6 cells, Naoto Shimizu, Hiroshi Ide, Masataka Tsuda, 2021/09/22, Without Invitation, Japanese
External Funds
Acceptance Results of Competitive Funds
- 2022, 2024
- 2022, 2025