TOSHINORI ANDO

Last Updated :2024/05/20

Affiliations, Positions
Hiroshima University Hospital(Center for Oral Clinical Examination), Associate Professor or Lecturer
Web Site
E-mail
toando19hiroshima-u.ac.jp
Other Contact Details
1-2-3 Kasumi, Minami-ku, Hiroshima, Japan 734-8551, Japan
TEL : (+81)82-257-5727 FAX : (+81)
Self-introduction
I work as an oral pathologist in the Hiroshima University Hospital. My research focuses on oral/head and neck squamous cell carcinoma, salivary gland tumor, odontogenic tumor, sarcoma. I try to clarify the mechanism by which their genetic alterations and aberrant signaling pathway causes carcinogenesis or cancer progression, which are expected to yield a novel therapy for the patients with cancer. I mainly focus on the Hippo pathway and mTOR pathway, as well as tumor-immunity, using various approaches including molecular pathological, molecular biological, bioinformatics, mouse genetics etc.

Basic Information

Major Professional Backgrounds

  • 2024/04/01, Center of Oral Clinical Examination, Hiroshima University Hospital, Senior Lecturer
  • 2020/10/01, Hiroshima University Hospital, Center for oral clinical examination, Assistant professor
  • 2020/04/01, 2020/09/30, Hiroshima University Hospital, Center for oral clinical examination, Dentist
  • 2018/09/01, 2020/03/31, Hiroshima University, Institute of Biomedical & Health Sciences, Assistant professor (Cross-appointment)
  • 2017/09/01, 2020/03/16, University of California, San Diego, Moores Cancer Center (PI: J. Silvio Gutkind), Postdoctoral employee
  • 2015/03/01, 2017/08/29, Hiroshima University, Institute of Biomedical & Health Sciences, Assistant Professor
  • 2013/04/01, 2015/02/28, Hiroshima University Hospital, Division of Special Dental Treatment, Clinical Staff
  • 2012/04/01, 2015/02/28, Japan Society for the Promotion of Science, Research fellowship for young scientists (Doctoral Course Students 1, DC1)
  • 2011/04/01, 2012/03/31, Hiroshima University Hospital, Hospital, Clinical Fellow
  • 2010/04/07, 2011/03/31, Hiroshima University Hospital, Hospital, Clinical Resident
  • 2010/04/01, 2010/04/06, Hiroshima University Hospital, Hospital, Clinical Resident

Educational Backgrounds

  • Hiroshima University, Graduate School of Biomedical Sciences, Japan, 2011/04, 2015/03
  • Hiroshima University, School of Dentistry , Japan, 2004/04, 2010/03

Academic Degrees

  • Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Pathobiological dentistry / Dental radiology

Research Keywords

  • oral/head and neck squamous cell carcinoma, salivary gland tumor, odontogenic tumor, sarcoma, EGFR, tyrosine kinases, Cetuximab, Hippo pathway, YAP/TAZ, mTOR pathway, molecular biology, signaling pathway, bioinformatics, mouse genetics

Affiliated Academic Societies

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, 3Term, Basic Oral Pathology I
  2. 2024, Undergraduate Education, 4Term, Basic Oral Pathology II
  3. 2024, Undergraduate Education, 1Term, Slide Practice for Oral Pathology I
  4. 2024, Undergraduate Education, 2Term, Slide Practice for Oral Pathology II
  5. 2024, Undergraduate Education, 3Term, Examination and Diagnosis
  6. 2024, Undergraduate Education, First Semester, Dental Research Practices I
  7. 2024, Undergraduate Education, Second Semester, Dental Research Practices II
  8. 2024, Undergraduate Education, First Semester, Dental Research Practices III
  9. 2024, Undergraduate Education, Academic Year, Clinical Practice (Oral Clinical Examination)
  10. 2024, Undergraduate Education, 1Term, Oral Health Management A
  11. 2024, Undergraduate Education, Second Semester, Clinical Practice in Oral Health Engineering
  12. 2024, Undergraduate Education, First Semester, Clinical Practice in Oral Health Engineering
  13. 2024, Undergraduate Education, Second Semester, Clinical Practice in Oral Health Engineering

Research Activities

Academic Papers

  1. Relationship of oral bacterial number with medical hospitalization costs in analysis of Diagnosis Procedure Combination database from single institution in Japan, Scientific Reports, 14(1), 11114, 20240515
  2. Extranodal extension in oral squamous cell carcinoma: clinical and histopathological analysis, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, in press, 20240322
  3. A case of supermassive cemento-ossifying fibroma in the mandible, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, in press, 20230207
  4. Transformation of an odontogenic keratocyst into a solid variant of odontogenic keratocyst/keratoameloblastoma during long‑term follow‑up: A case report, Molecular Medicine Reports, 29(44), 20240119
  5. Distinctive Biological Properties between Mesenchymal Stem Cell Spheroids and Clumps of Mesenchymal Stem Cells/Extracellular Matrix Complexes in 3D Culture Systems, Applied Sciences, 13(23), 12790, 20231129
  6. Mechanosignaling YAP/TAZ-TEAD Axis Regulates the Immunomodulatory Properties of Mesenchymal Stem Cells, Stem Cell Reviews and Reports, 20231102
  7. YAP/TAZ interacts with RBM39 to confer resistance against indisulam, preprint, 20231018
  8. A kinome-wide synthetic lethal CRISPR/Cas9 screen reveals that mTOR inhibition prevents adaptive resistance to CDK4/CDK6 blockade in HNSCC, preprint, 20230807
  9. Ultrasonographic features of mass lesions in the oral submucosal epithelium using intraoral ultrasonography, Head & Neck, 45(11), 2829-2838, 20230907
  10. Relationship between CD4+ T-cell counts at baseline and initial periodontal treatment efficacy in patients undergoing treatment for HIV infection: A retrospective observational study, Journal of Clinical Periodontology, 50(11), 1520-1529, 20230904
  11. Taste-taste associations in chemotherapy-induced subjective taste alterations: findings from a questionnaire survey in an outpatient clinic, Supportive Care in Cancer, 31(9), 552, 20230902
  12. ★, AXL activates YAP through the EGFR–LATS1/2 axis and confers resistance to EGFR-targeted drugs in head and neck squamous cell carcinoma, Oncogene, 20230817
  13. A case report of allergic reaction with acute facial swelling: a rare complication of dental acrylic resin, Journal of International Medical Research, 51(7), 20230722
  14. Resting saliva volume as a risk factor for hypogeusia: A retrospective study, Physiology & Behavior, 267, 20230801
  15. Ghost cell odontogenic carcinoma arising in dentinogenic ghost cell tumor, peripheral: A case report, Pathology International, 1-6, 20230704
  16. A Cartilaginous Construct with Bone Collar Exerts Bone-Regenerative Property Via Rapid Endochondral Ossification, Stem Cell Reviews and Reports, 20230511
  17. A case of multiple myeloma diagnosed by extramedullary disease in the submandibular region, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 35(3), 247-250, 202305
  18. Secretory carcinoma of the minor salivary gland in the lip with ETV6-NTRK3 fusion: case report and literature review, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 35(3), 251-257, 202305
  19. Primary intraosseous carcinoma complicated by cervical hodgkin lymphoma: A rare case report, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, in press, 20230427
  20. Retrospective study on the therapeutic efficacy of zinc acetate hydrate administration to patients with hypozincemia-induced dysgeusia, BMC Oral Health, 23(1), 159-159, 20230318
  21. A Third Supernumerary Tooth Occurring in the Same Region: A Case Report, dentistry journal, 11(2), 49, 20230212
  22. Bovine Lactoferrin Suppresses Tumor Angiogenesis through NF-kB Pathway Inhibition by Binding to TRAF6, pharmaceutics, 15(1), 165, 20230103
  23. A clinical study on oral cancer patients treated with immune checkpoint inhibitors, Journal of the Japanese Stomatological Society, 71(3), 161-172, 20221012
  24. A case of Trousseau syndrome caused by tongue cancer with lung metastases during pharmacotherapy in an adolescent and young adult patient, Jon. J. Oral Maxillofac. Surg., 68(9), 362-369, 20220628
  25. Integrating Genetic Alterations and the Hippo Pathway in Head and Neck Squamous Cell Carcinoma for Future Precision Medicine, Journal of Personalized Medicine, 12(10), 1544, 20220920
  26. A Case of Cystadenoma of the Palate, The Journal of Hiroshima University Dental Society, 54(1), 34-38, 20220601
  27. Non-sebaceous lymphadenoma-like mucoepidermoid carcinoma: A case report, Pathology International, 20220521
  28. Oral administration of bovine lactoferrin suppresses the progression of rheumatoid arthritis in an SKG mouse model, PLoS One, 17(2), e0263254, 20220211
  29. ★, EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1, Communications biology, 4(1237), 20211101
  30. A case of maxillary ameloblastic carcinoma with atypical histology, JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY, 33(5), 536-545, 202109
  31. Four Cases of Extranodal Zone Lymphoma of the Mucosa-Associated Lymphoid Tissue (MALT lymphoma) of Salivary Gland in the Oral Cavity, The Journal of Hiroshima University Dental Society, 53(1), 30-37, 20210601
  32. Development of Kikuchi-Fujimoto disease after a cervical lymph node metastasis of mucoepidermoid carcinoma: a case report., Oral and Maxillofacial Surgery, 25(1), 133-137, 202103
  33. Pathway-Specific Genome Editing of PI3K/mTOR Tumor Suppressor Genes Reveals that PTEN Loss Contributes to Cetuximab Resistance in Head and Neck Cancer, MOLECULAR CANCER THERAPEUTICS, 19(7), 1562-1571, 2020
  34. Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK-YAP signaling axis, ONCOGENE, 39(20), 4014-4027, 2020
  35. Metformin Inhibits Progression of Head and Neck Squamous Cell Carcinoma by Acting Directly on Carcinoma-Initiating Cells, CANCER RESEARCH, 79(17), 4360-4370, 2019
  36. ★, The transition of tissue inhibitor of metalloproteinases from-4 to-1 induces aggressive behavior and poor patient survival in dedifferentiated liposarcoma via YAP/TAZ activation, CARCINOGENESIS, 40(10), 1288-1297, 2019
  37. ★, Tissue inhibitor of metalloproteinase-1 promotes cell proliferation through YAP/TAZ activation in cancer, ONCOGENE, 37(2), 263-270, 2018
  38. Comparison of the bone regeneration ability between stem cells from human exfoliated deciduous teeth, human dental pulp stem cells and human bone marrow mesenchymal stem cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 497(3), 876-882, 2018
  39. Central mucoepidermoid carcinoma arising from glandular odontogenic cyst confirmed by analysis of MAML2 rearrangement: A case report, PATHOLOGY INTERNATIONAL, 68(1), 31-35, 2018
  40. Galectin-3 Plays an Important Role in Preterm Birth Caused by Dental Infection of Porphyromonas gingivalis, SCIENTIFIC REPORTS, 8, 2018
  41. A case of primordial odontogenic tumor: A new entity in the latest WHO classification (2017), PATHOLOGY INTERNATIONAL, 67(7), 365-369, 201707
  42. ★, Ameloblastin induces tumor suppressive phenotype and enhances chemosensitivity to doxorubicin via Src-Stat3 inactivation in osteosarcoma, SCIENTIFIC REPORTS, 7, 2017
  43. N-terminal region of human ameloblastin synthetic peptide promotes bone formation, ODONTOLOGY, 105(1), 116-121, 201701
  44. Infection with Porphyromonas gingivalis Exacerbates Endothelial Injury in Obese Mice, PLOS ONE, 9(10), 2014
  45. A Case of Focal Osseous Dysplasia Arising Bilaterally in the Mandible Detected by Long-term Observation by a Family Dentist, 45(1), 33-38, 201306
  46. Periostin Directly and Indirectly Promotes Tumor Lymphangiogenesis of Head and Neck Cancer, PLOS ONE, 7(8), 2012
  47. Nuclear Survivin expression is correlated with malignant behaviors of head and neck cancer together with Aurora-B, ORAL ONCOLOGY, 46(4), 263-270, 2010

Publications such as books

  1. Medical Technology, 2022, 06, Scholarly Book, Joint work, 日本語, B0B289X27K

Invited Lecture, Oral Presentation, Poster Presentation

  1. YAP/RBM39 interaction confers resistance to indisulam in oral squamous cell carcinoma, Ando T, Okamoto K, Shintani T, Yanamoto S, Miyauchi M, Kajiya M, The 113th Annual Meeting of the Japanese Society of Pathology, 2024/03/28, Without Invitation, English, The Japanese Society of Pathology, Aichi
  2. YAP/TAZ confers resistance against splicing inhibitors in head and neck squamous cell carcinoma, Ando T, Okamoto K, Shintani T, Yanamoto S, Miyauchi M, Kajiya M, The 82nd annual meeting of the Japanese Cancer Association, 2023/09/23, Without Invitation, English, Japanese Cancer Association, Yokohama
  3. Deciphering the mechanism of cancer immune evasion induced by disruption of the Hippo pathway, Ando T, Okamoto K, Yanamoto S, Miyauchi M, Kajiya M, The 34th Annual Meeting of the Japanese Society of Oral Pathology, 2023/08/26, Without Invitation, Japanese, The Japanse Society of Oral Pathology, Osaka
  4. Innovative cancer immunotherapy using peptide targeting novel molecular interaction with YAP/TAZ, Ando T, BioJapan 2022, 2022/10/12, Without Invitation, Japanese, Yokohama
  5. Novel regulatory mechanism of the Hippo pathway by AXL, Ando T, Okamoto K, Yanamoto S, Miyauchi M, 2022/09/23, Without Invitation, Japanese
  6. AXL activates YAP and confers resistance to EGFR inhibitors in oral squamous cell carcinoma, Okamoto K, Ando T, Kajiya M, Yanamoto S, Miyauchi M, The 55th Annual Meeting of the Dental Association of Hiroshima University, 2022/06/11, Without Invitation, English, The Dental Association of Hiroshima University, Hiroshima
  7. Deciphering mechanism of AXL-mediated YAP activation and resistance to EGFR inhibitor in oral squamous cell carcinoma, Okamoto K, Ando T, Toratani T, Yanamoto S, Miyauchi M, The 76th Annual Meeting of Japanese Stomatological Society, 2022/04/21, Without Invitation, Japanese, Japanese Stomatological Society, Fukuoka
  8. Regulatory mechanism of the Hippo pathway by genetic alterations in cancer, Ando T, The 72th HiHA Webinar, 2022/03/03, With Invitation, Japanese, Hiroshima Research Center for Healthy Aging (HiHA), Hiroshima
  9. A case of giant cell tumor in the mandibular condyle, Ito N., Koizumi K., Obayashi F., Sakamoto S., Ando T., Toratani S, The 66th Congress of the Japanese Society of Oral and Maxillofacial Surgeons, 2021/11/12, Without Invitation, Japanese, The Japanese Society of Oral and Maxillofacial Surgeons, Makuhari, Hybrid
  10. A case of non-sebaceous lymphadenoma-like mucoepidermoid carcinoma, Sakamoto S, Ando T, Miyauchi M, Fujiwara M, Nakaguro M, Nagao T, Ogawa I, 2021/11/27, Without Invitation, Japanese, Japan Salivary Gland Society, Tokyo
  11. A case of clear cell carcinoma diagnosed by identification of EWSR1-ATF1 fusion gene, Higaki M., Yoshioka Y., Okamoto K., Sakamoto S., Ando T., Okamoto K., Miyauchi M., Toratani S, The 66th Congress of the Japanese Society of Oral and Maxillofacial Surgeons, 2021/11/12, Without Invitation, Japanese, The Japanese Society of Oral and Maxillofacial Surgeons, Makuhari, Hybrid
  12. Palatal tumor (Polymorphous adenocarcinoma), Furusho H, Sakamoto S, Ando T, Ono S, Mizuta K, Ishida Y, Uetsuki R, Nagasaki S, Takechi M, Miyauchi M, 2021/10/23, Without Invitation, Japanese
  13. Analysis of genetic alterations and disregulation of the Hippo signaling pathway in oral cancer, The 14th Annual Meeting of the Japanese Society for Evidence and the Dental Professional, 2021/08/21, With Invitation, Japanese, Japanese Society for Evidence and the Dental Professional, Hiroshima (WEB)
  14. Importance of anti-centromere antibodies in the diagnosis of Sjogren's syndrome: a focus on oral findings, Kitagawa M, Sugimoto T, Ando T, Kajiya M, Ogawa I, Shiba H, Sugiyama E, The 14th Annual Meeting of the Japanese Society for Evidence and the Dental Professional, 2021/08/21, Without Invitation, Japanese, Japanse Society for Evidence and the Dental Professional, Hiroshima (WEB)
  15. Maxillary tumor (Odontogenic fibroma, amyloid variant), Sakamoto S, Ando T, Ito N, Kanda T, Suei Y, Toratani S, Miyauchi M, The 32nd annual meeting of the Japanese Society of Oral Pathology, 2021/08/12, Without Invitation, Japanese, The Japanese Society of Oral Pathology, Kanagawa, WEB
  16. A clinical study on oral cancer patients treated with immune checkpoint inhibitors in department of oral and maxillofacial surgery, Yoshioka Y., Ono S., Tani R., Mizuta K., Nakagawa T., Ando T., Sakamoto S., Takechi M., Toratani S., Okammoto T, The 115th Annual meeting of Society of Clinical Oncology Hiroshima, 2021/07/03, Without Invitation, Japanese, Society of Clinical Oncology Hiroshima, Hiroshima
  17. Maxillary tumor (Clear cell carcinoma), Toshinori Ando, Shinnichi Sakamoto, Mirai Higaki, Kento Okamoto, Yukio Yoshioka, Shigeaki Toratane, Takashi Nakamoto, Kosei Okamoto, Hiro Matsuura, Mayumi Kaneko, Ikuko Ogawa, Mutsumi Miyauchi, 2021/06/19, Without Invitation, Japanese
  18. Third supernumerary tooth occurring in the same region during follow-up after the second supernumerary tooth extraction, Akimoto T, Asao Y, Iwamoto Y, Mitsuhata C, Ando T, Sakamoto S, Kozai K, The 28th Congress of the International Association of Paediatric Dentistry (IAPD), 2021/06/10, Without Invitation, English, International Association of Paediatric Dentistry, Virtual Congress
  19. Workshop 9/Salivary gland cytology- Application and explanation of Milan system- WS9-2 Salivary gland tumors in the oral region, Sakamoto S, Ando T, Ogawa I, Miyauchi M, The 62nd Annual Spring Meeting of the Japanese Society of Clinical Cytology, 2021/06/04, With Invitation, Japanese, The Japanese Society of Clinical Cytology, Chiba
  20. A clinical study on oral cancer patients treated with immune checkpoint inhibitors in department of oral and maxillofacial surgery, Hiroshima University Hospital, Yoshioka Y, Ono S, Tani R, Mizuta K, Nakagawa T, Ando T, Sakamoto S, Takechi M, Toratani S, Okamoto T, The 75th Annual Meeting of the Japanese Stomatological Society, 2021/05/12, Without Invitation, Japanese, The Japanese Stomatological Society, Osaka, Web
  21. Role of EGFR-mediated MOB1 phosphorylation on Hippo pathway regulation, Toshinori Ando, The 68th Annual Meeting of Japanese Association for Dental Research, 2020/11/07, Without Invitation, English, Japanese Association for Dental Research (JADR), Online
  22. Regulation of the Hippo Pathway by the EGFR-mediated tyrosine phosphorylation of MOB1., Toshinori Ando, The 31st annual meeting of the Japanese Society of Oral Pathology, 2020/10/06, Without Invitation, Japanese, The Japanese Society of Oral Pathology, Nagoya
  23. Mandibular gingival tumor (Ghost cell odontogenic carcinoma arising in dentinogenic ghost cell tumor), Shinnichi Sakamoto, Toshinori Ando, Kuniko Mizuta, Fumi Ishida, Daiki Kato, Shigehiro Ono, Masaru Konishi, Mutsumi Miyauchi, Ikuko Ogawa, The 31st annual meeting of the Japanese Society of Oral Pathology, 2020/10/06, Without Invitation, Japanese, the Japanese Society of Oral Pathology, Nagoya
  24. EGFR regulates the Hippo Pathway by the Direct Tyrosine phosphorylation of MOB1, Toshinori Ando, The 79th annual meeting of the Japanese Cancer Association, 2020/10/01, Without Invitation, English, Japanese Cancer Association, Hiroshima
  25. EGFR Regulates the Hippo Pathway by the Direct Tyrosine Phosphorylation of MOB1, Ando T, Happy hour lecture in Moores Cancer Center, 2020/02/06, With Invitation, English, Moores Cancer Center, University of California, San Diego, San Diego
  26. Regulation of the Hippo pathway through EGFR-mediated tyrosine phosphorylation of MOB1, Ando T, Arang N, Costea DE, Feng X, Goto Y, Izumi H, Gilardi M, Gutkind JS, MCC Annual Scientific Retreat, 2019/10/01, Without Invitation, English, Moores Cancer Center, University of California, San Diego, San Diego, USA
  27. The transition of tissue inhibitor of metalloproteinase-4 to -1 expression modulates YAP/TAZ mediated aggressive phenotype in liposarcoma., Madhu Shrestha, Toshinori Ando, Ikuko Ogawa, Mutsumi Miyauchi, Takashi Takata, Joint International Association of Oral Pathology and American Academy of Oral & Maxillofacial Pathology Meeting, 2018/06/22, Without Invitation, English, International Association of Oral Pathology, Vancouver
  28. The transition of tissue inhibitor of metalloproteinase-1 and -4 expressions induces aggressive behavior and poor patient survival in dedifferentiated liposarcoma via YAP/TAZ activation., Madhu Shrestha, Toshinori Ando, Chea Chanbora, Ikuko Ogawa, Mutsumi Miyauchi, Takashi Takata, 7th Hiroshima Conference on Education and Science in Dentistry, 2018/03/29, Without Invitation, Japanese, Hiroshima University, Hiroshima
  29. Ameloblastin induces tumor suppressive phenotype and enhances chemosensitivity to doxorubicin via Src-Stat3 inactivation in osteosarcoma., Toshinori Ando, 2017/08/24, Without Invitation, Japanese, Saitama
  30. The transition of tissue inhibitor of metalloproteinase-1 and -4 expressions induces aggressive behavior and poor patient survival in dedifferentiated liposarcoma via YAP/TAZ activation., Shrestha M, Ando T, Ogawa I, Miyauchi M, Takata T, 2017/08/24, Without Invitation, English
  31. The transition of tissue inhibitor of metalloproteinase-1 and -4 expressions induces aggressive behavior and poor patient survival in dedifferentiated liposarcoma via YA P/TAZ activation., Shrestha M, Ando T, Ogawa I, Miyauchi M, Takata T., 50th General meeting of the Hiroshima University Dental Society, 2017, Without Invitation, English, Hiroshima University
  32. Ameloblastin induces tumor suppression and chemosensitivity in osteosarcoma., Ando T, Shrestha M, Kudo Y, Tsunematsu T, Ogawa I, Miyauchi M, Takata T, 18th International Congress on Oral Pathology and Medicine & XXV Conference of Indian Association of Oral and Maxillofacial Pathologists, 2016/09/11, Without Invitation, English, India, Chennai
  33. Novel regulation of tumor growth by tissue inhibitor of metalloproteinases (TIMP-1 and 4) in sarcomas, Shrestha M, Ando T, Nishisaka T, Ogawa I, Miyauchi M, Takata T, 18th International Congress on Oral Pathology and Medicine & XXV Conference of Indian Association of Oral and Maxillofacial Pathologists, 2016/09/11, Without Invitation, English, India, Chennai
  34. Oncogenic role of tissue inhibitor of metalloproteinase-1, TIMP-1, through regulation of YAP in HNSCC, Dyshafilia Charindra, Shrestha M, Ando T, Takata T, The 27th annual meeting of the Japanese Society of Oral Pathology, 2016/08/12, Without Invitation, English, Hiroshima
  35. Ameloblastin induces tumor suppression and chemosensitivity in osteosarcoma doxorubicin in osteosarcoma, Ando T, Umehara H, Miyauchi M, Ogawa I, Takata T, The 26th Annual Meeting of the Japanese Society of Oral Pathology, 2015/07/31, Without Invitation, Japanese, Sapporo
  36. Feedback activation of Stat3 induces resistance to doxorubicin in osteosarcoma, Umehara H, Ando T, Takata T, The 26th Annual Meeting of the Japanese Society of Oral Pathology, 2015/07/31, Without Invitation, Japanese, Sapporo
  37. Feedback activation of Stat3 induces resistance to doxorubicin in osteosarcoma, Umehara H, Charindra D, Ando T, Takata T, 48th annual meeting of the Dental Association of Hiroshima University, 2015/06/27, Without Invitation, Japanese, Hiroshima
  38. Ameloblastin enhances chemosensitivity to doxorubicin via Src-Stat3 inactivation in osteosarcoma, Ando T, Ogawa I, Miyauchi M, Takata T, The 104th Annual Meeting of the Japanese Society of Pathology, 2015/05/01, Without Invitation, English, Nagoya
  39. Ameloblastin Induces Tumor Suppression and Chemosensitivity in Osteosarcoma., Ando T, Ogawa I, Miyauchi M, Takata T, 93rd General Session & Exhibition of the International Association for Dental Research, 2015/03/13, Without Invitation, English, Boston
  40. Significance of fusion gene analysis for the differential diagnosis of mucoepidermoid carcinoma., Nagasaki A, Ando T, Obayashi M, Ogawa I, Takata T., 17th International Congress on Oral Pathology and Medicine, 2014/05/29, Without Invitation, Japanese
  41. Oncogenic role of TIMP-1 in sarcoma., Ando T, Umehara H, Nishizaka T, Miyauchi M, Takata T., 103rd annual meeting of the Japanese Society of Pathology, 2014/04/26, Without Invitation, Japanese, Hiroshima
  42. Tumor suppressive role of Ameloblastin through Src inactivation in osteosarcoma, Ando T, Kudo Y, Iizuka S, Tsunematsu T, Matsuo T, Kubo T, Shimose S, Ochi M, Arihiro K, Miyauchi M, Ogawa I, and Takata T, 5th Hiroshima Conference on Education and Science in Dentistry, 2013/10/12, Without Invitation, English
  43. The novel tumor suppressor function of Ameloblastin in osteosarcoma, Ando T, Tsunematsu T, Kudo Y, Ogawa I, Miyauchi M, and Takata T, 91st General Session and Exhibition of the International Association for Dental Research, 2013/03/20, Without Invitation, English, International Association for Dental Research, Seattle USA
  44. The novel tumor suppressor function of Ameloblastin in osteosarcoma, The 60th Annual Meeting of Japanese Association for Dental Research, 2012/12/14, Without Invitation, English, Japanese Association for Dental Research, Niigata
  45. The novel function of Ameloblastin as a tumor suppressor gene in osteosarcoma, Ando T, Tsunematsu T, Kudo Y, Ogawa I, Miyauchi M, Takata T, The 45th annual meeting of the Dental Association of Hiroshima university, 2012/05/17, Without Invitation, English, Dental Association of Hiroshima university, Hiroshima Univerisity
  46. Abnormal expression of Evi5 and its role for cancer development, Ando T, Kudo Y, Tsunematsu T, Takata T, 42nd annual meeting of the Dental Association of Hiroshima University, 2009, Without Invitation, Japanese

Awards

  1. 2023/11/12, Oral presentation award (as a co-presenter), 第68回 日本口腔外科学会総会・学術大会, AXLはYAPを活性化しEGFR阻害薬への耐性を付与する
  2. 2021/10/23, Presentation award, 日本病理学会中国四国支部, Maxillary tumor (Clear cell carcinoma)
  3. 2020/11/21, JADR/GC Young Investigator Award 2020, Japanese Association for Dental Research (JADR), Role of EGFR-mediated MOB1 phosphorylation on Hippo pathway regulation
  4. 2020/10/06, Presentation award, The 31st Annual Meeting of the Japanese Society of Oral Pathology, Mandibular gingival tumor (Ghost cell odontogenic carcinoma arising from dentinogenic ghost cell tumor, peripheral type)
  5. 2020/10/06, Presentation award, The 31st Annual Meeting of the Japanese Society of Oral Pathology, Regulation of the Hippo Pathway by the EGFR-mediated tyrosine phosphorylation of MOB1
  6. 2016/09/11, Poster Prize, International Association of Oral Pathologists, Ameloblastin Induces Tumor Suppression and Chemosensitivity in Osteosarcoma
  7. 2013/10/13, Poster award, 5th Hiroshima Conference on Education and Science in Dentistry
  8. 2013/03/21, IADR/Unilever Hatton Divisional Award, IADR

External Funds

Acceptance Results of Competitive Funds

  1. Grants-in-Aid for Scientific Research B, Deciphering the mechanism of cancer microenvironment by disruption of the Hippo pathway and development of novel therapeutic approach, 2024/04/01, 2027/03/31
  2. The Hiroshima University Fund "Nozomi H Foundation" subsidy for the promotion of cancer treatment research, Analysis of novel nuclear YAP-interacting molecule for cancer treatment, 2022/04/01, 2023/03/31
  3. 2021/01/01, 2021/12/31
  4. Grants-in-Aid for Scientific Research, 2020/04/01, 2023/03/01
  5. 2017/04/01, 2020/03/31
  6. Grants-in-Aid for Scientific Research, 2017/04/01, 2018/03/31
  7. Grants-in-Aid for Scientific Research, 2016/04/01, 2019/03/31
  8. 2014/04/01, 2015/03/31
  9. 2012/04/01, 2015/03/31

Social Activities

Other Social Contributions

  1. The 14th Annual Meeting of the Japanese Society for Evidence and the Dental Professional, Symposium, Japanse Society for Evidence and the Dental Professional, 2021/08/21, 2021/08/22, Hiroshima (WEB), Presenter, Meeting or assembly, Researchesrs

History as Peer Reviews of Academic Papers

  1. 2024, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, Others, Reviewer, 1
  2. 2024, BMC Cancer, Others, Reviewer, 2
  3. 2024, Oncogene, Others, reviewer, 1
  4. 2023, Oncogene, Others, reviewer, 2
  5. 2023, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, Others, reviewer, 5
  6. 2023, Oral Diseases, Others, reviewer, 1
  7. 2021, International journal of oral science, Others, reviewer, 2
  8. 2021, Oral Diseases, Others, Reviewer, 6
  9. 2018, Oncogene, Others, Reviewer, 1