Masae Kitagawa

Last Updated :2021/05/11

Affiliations, Positions
Hiroshima University Hospital(Center for Oral Clinical Examination), Assistant Professor
E-mail
mhiraokahiroshima-u.ac.jp
Self-introduction
Aiming to develop new dental treatments, we are conducting examinations, dental treatments, and research. My specialty is oral examination, dry mouth, and allergies.

Basic Information

Academic Degrees

  • Doctor of Philosophy in Dental Science, Hiroshima University

Educational Activity

  • 【Bachelor Degree Program】School of Dentistry : Program of Dentistry

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Morphological basic dentistry

Research Keywords

  • oral examination
  • dry mouth
  • metal allergy/ dental material allergy
  • cementoblast

Educational Activity

Course in Charge

  1. 2021, Undergraduate Education, 1Term, Oral Health Management A
  2. 2021, Undergraduate Education, Academic Year, Clinical Practice (Oral Clinical Examination)
  3. 2021, Undergraduate Education, Second Semester, Clinical Practice in Oral Health Engineering
  4. 2021, Undergraduate Education, First Semester, Clinical Practice in Oral Health Engineering
  5. 2021, Undergraduate Education, Second Semester, Clinical Practice in Oral Health Engineering

Research Activities

Academic Papers

  1. Identification of regulatory mRNA and microRNA for differentiation into cementoblasts and periodontal ligament cells, JOURNAL OF PERIODONTAL RESEARCH, 56(1), 69-82, 202101
  2. Oral environment and taste function of Japanese HIV-infected patients treated with antiretroviral therapy, AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV, 32(7), 829-834, 20200702
  3. ★, Rapid detection of the Streptococcus mutans cnm gene by loop-mediated isothermal amplification, ANALYTICAL BIOCHEMISTRY, 605, 20200915
  4. ★, Current status of dental metal allergy in Japan, JOURNAL OF PROSTHODONTIC RESEARCH, 63(3), 309-312, 201907
  5. Central mucoepidermoid carcinoma arising from glandular odontogenic cyst confirmed by analysis of MAML2 rearrangement: A case report, PATHOLOGY INTERNATIONAL, 68(1), 31-35, JAN 2018
  6. Effects of interleukin-1 beta on human follicular dendritic cell-secreted protein gene expression in periodontal ligament cells, JOURNAL OF ORAL SCIENCE, 60(4), 601-610, 201812
  7. Baicalin Promotes Osteogenic Differentiation of Human Cementoblast Lineage Cells Via the Wnt/beta Catenin Signaling Pathway, CURRENT PHARMACEUTICAL DESIGN, 24(33), 3980-3987, 2018
  8. N-terminal region of human ameloblastin synthetic peptide promotes bone formation, ODONTOLOGY, 105(1), 116-121, 201701
  9. Human odontogenic epithelial cells derived from epithelial rests of Malassez possess stem cell properties, LABORATORY INVESTIGATION, 96(10), 1063-1075, OCT 2016
  10. Expression of Wilms' tumor 1 (WT1) in ameloblastomas, JOURNAL OF ORAL SCIENCE, 58(3), 407-413, SEP 2016
  11. Distinction Between Cell Proliferation and Apoptosis Signals Regulated by Brain-Derived Neurotrophic Factor in Human Periodontal Ligament Cells and Gingival Epithelial Cells, JOURNAL OF CELLULAR BIOCHEMISTRY, 117(7), 1543-1555, JUL 2016
  12. F-Spondin Inhibits Differentiation of Clastic Precursors via Lipoprotein Receptor-Related Protein 8 (LRP8), JOURNAL OF PERIODONTOLOGY, 86(3), 465-472, MAR 2015
  13. The differential expression of mgl mRNA by Porphyromonas gingivalis affects the production of methyl mercaptan, ORAL DISEASES, 21(5), 626-633, JUL 2015
  14. Dental Infection of Porphyromonas gingivalis Induces Preterm Birth in Mice, PLOS ONE, 10(8), AUG 31 2015
  15. BDNF mimetic compound LM22A-4 regulates cementoblast differentiation via the TrkB-ERK/Akt signaling cascade, INTERNATIONAL IMMUNOPHARMACOLOGY, 19(2), 245-252, 20140401
  16. Infection with Porphyromonas gingivalis Exacerbates Endothelial Injury in Obese Mice, PLOS ONE, 9(10), 20141021
  17. Comprehensive Oral Management for Collaborative Medical and Dental Care -Practical Approaches for Oral Care Support Team-, The Journal of Hiroshima University Dental Society, 45(1), 1-6, 20130601
  18. ★, F-spondin regulates the differentiation of human cementoblast-like (HCEM) cells via BMP7 expression, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 418(2), 229-233, 20120210
  19. Synthetic ameloblastin peptide stimulates differentiation of human periodontal ligament cells., Archives Oral Biology, 56(4), 376-9, 20110301
  20. Brain-derived neurotrophic factor protects cementoblasts from serum starvation-induced cell death., J Cell Physiol, 221(3), 696-706, 20091201
  21. Prostaglandin E2 inhibits mineralization and enhances matrix metalloproteinase-13 in mature cementoblasts mainly via the EP4 pathway., Archives of Oral Biology, 53(3), 243-249, 20080301
  22. Effects of ultrasound on the proliferation and differentiation of cementoblast lineage cells., J Periodontol, 79(10), 1984-1990, 20081001
  23. Brain-derived neurotrophic factor stimulates bone/cementum-related protein gene expression in cementoblasts., J Biol Chem., 283(23), 16259-16267, 20080601
  24. Prostaglandin E2 inhibits mineralization and enhances matrix metalloproteinase-13 in mature cementoblasts mainly via the EP4 pathway., Arch Oral Biol, 53(3), 243-249, 20080301
  25. ★, Immortalization and characterization of human dental pulp cells with odontoblastic differentiation., Archives of Oral Biology, 52(8), 727-731, 20070801
  26. ★, Immortalization and characterization of pleomorphic adenoma cells by transfection with the hTERT gene., International Journal Of Oncology, 31(2), 339-344, 20070801
  27. Enamel Matrix Derivative Exhibits Anti-inflammation Properties in Monocytes, Journal of Periodontology, IN PRESS, 20071201
  28. ★, Characterization of established cementoblast-like cell lines from human cementum lining cells in vitro and in vivo., Bone, 39(5), 1035-1042, 20061101
  29. ★, Effect of F-spondin on cementoblastic differentiation of human periodontal ligament cells., Biochem. Biophys. Res. Commun., 349, 1050-1056, 20060401
  30. Establishment and characterization of a spindle cell squamous carcinoma cell line, Journal of Oral Pathology and Medicine, 35, 479-483, 20060401
  31. Periostin promotes invasion and anchorage-independent growth in the metastatic process of head and neck cancer, Cancer Research, 66, 6928-6935, 20060401
  32. Characteristics of periodontal ligament subpopulations obtained by sequential enzymatic digestion of rat molar periodontal ligament., BONE, 38, 420-426, 20060401
  33. Effects of endogenous and exogenous prostaglandin E2 on the proliferation and differentiation of a mouse cementoblast cell line (OCCM-30)., Journal of Preiodontology, 77(12), 2051-2058, 20061201
  34. Periostin is frequently overexpressed and enhances invasion and angiogenesis in oral cancer, British Journal of Cancer, 95(10), 1396-1403, 20060401
  35. ★, Establishment of cementoblast cell lines from rat cementum lining cells by transfection with temperature-sensitive simian virus-40 T-antigen gene., BONE, 37, 220-226, 20050401
  36. Small interfering RNA targeting of S phase kinase-interacting protein 2 inhibits cell growth of oral cancer cells by inhibiting p27 degradation., Molecular Cancer Therapy, 4, 471-476, 20050401
  37. Immunolocalization of CXC chemokine and recruitment of polymorphonuclear leukocytes in the rat molar periodontal tissue after topical application of lipopolysaccharide., Histochemistry and Cell Biology, 121, 291-297, 20040401
  38. Immuno-localization of COX-1 and COX-2 in the rat molar periodontal tissue after topical application of lipopolysaccharide., Archives of Oral biology, 49, 739-746, 20040401
  39. Invasion and metastasis of oral cancer cells require methylation of E-cadherin and/or degradation of membranous beta-catenin., Clinical Cancer Research, 10, 5455-5463, 20040401
  40. Upregulated CD44v9 expression inhibits the invasion of oral squamous cell carcinoma cells., Pathobiology, 71, 171-175, 20040401
  41. Role of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradation., American Journal of Pathology, 165, 2147-2155, 20040401
  42. Inhibition of CD44v9 upregulates the invasion ability of oral squamous cell carcinoma cells., Oral Oncology, 39, 27-30, 20030401
  43. Establishment of human cementifying fibroma cell lines by transfection with temperature-sensitive simian virus-40 T-antigen gene and hTERT gene., BONE, 30, 712-717, 20020401
  44. Effects of enamel matrix derivative on proliferation and differentiation of periodontal cells, J. Dental Res., 80, 771, 20010601
  45. Cytokine expression in rat molar gingival periodontal tissues after topical application of lipopolysaccharide, Histochem Cell Biol, 116, 57-62, 20010401

Invited Lecture, Oral Presentation, Poster Presentation

  1. Effects of inflammatory cytokines on human FDC-SP gene expression., 2015/10, Without Invitation, Japanese
  2. Comparative investigation of transcriptional regulatory mechanism of bone sialoprotein in osteoblast- and cementoblast-like cells., Noda K, Yamazaki M, Iwai Y, Matsui S, Kato A, Takai H, Nakayama Y, Kitagawa M, Takata T, Ogata Y, 2015/10, Without Invitation, Japanese
  3. Effect of F-spondin on LPS-induced periodontal inflammation and bone destruction, Masae Kitagawa, Mutsumi Miyauchi, Takashi Takata, 5th Hiroshima conference on education and science in dentistry, 2013, Without Invitation, English

Social Activities

History as Committee Members

  1. Director, 2018, Japan society for evidence and the dental professional