RYO YUGE

Last Updated :2021/10/05

Affiliations, Positions
Hiroshima University Hospital(Endoscopy), Assistant Professor
E-mail
makapoohiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Gastroenterology

Educational Activity

Course in Charge

  1. 2021, Undergraduate Education, Year, Clinical diagnosis and treatment I
  2. 2021, Undergraduate Education, Intensive, Introduction to clinical clerkship
  3. 2021, Undergraduate Education, Intensive, Practice for medical research
  4. 2021, Undergraduate Education, Intensive, Practice of Medicine I
  5. 2021, Undergraduate Education, Intensive, Practice of Medicine II
  6. 2021, Graduate Education (Doctoral Program) , First Semester, Advanced research on Gastroenterology and Metabolism
  7. 2021, Graduate Education (Doctoral Program) , Second Semester, Advanced research on Gastroenterology and Metabolism
  8. 2021, Graduate Education (Doctoral Program) , First Semester, Advanced research on Endoscopy and Medicine
  9. 2021, Graduate Education (Doctoral Program) , Second Semester, Advanced research on Endoscopy and Medicine
  10. 2021, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Gastroenterology and Metabolism
  11. 2021, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Gastroenterology and Metabolism
  12. 2021, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Gastroenterology and Metabolism
  13. 2021, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Gastroenterology and Metabolism
  14. 2021, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Endoscopy and Medicine
  15. 2021, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Endoscopy and Medicine
  16. 2021, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Endoscopy and Medicine
  17. 2021, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Endoscopy and Medicine

Research Activities

Academic Papers

  1. Propofol Activates and Allosterically Modulates Recombinant Protein Kinase C epsilon, ANESTHESIOLOGY, 111(1), 36-43, 2009
  2. Propofol Modulates Agonist-induced Transient Receptor Potential Vanilloid Subtype-1 Receptor Desensitization via a Protein Kinase C epsilon-dependent Pathway in Mouse Dorsal Root Ganglion Sensory Neurons, ANESTHESIOLOGY, 113(4), 833-844, 2010
  3. Combining Molecular Targeted Drugs to Inhibit Both Cancer Cells and Activated Stromal Cells in Gastric Cancer, NEOPLASIA, 15(12), 1391-1399, 2013
  4. Interaction between bone marrow-derived mesenchymal stem cells and tumor cells induces metallothionein gene expression in human colon cancer, CANCER RESEARCH, 73(8), 2013
  5. mTOR and PDGF Pathway Blockade Inhibits Liver Metastasis of Colorectal Cancer by Modulating the Tumor Microenvironment, AMERICAN JOURNAL OF PATHOLOGY, 185(2), 399-408, 2015
  6. Combining molecular targeted drugs to inhibit both cancer cells and activated stromal cells in colon cancer, CANCER RESEARCH, 74(19), 2014
  7. Interaction between bone marrow-derived mesenchymal stem cells and tumor cells induces expression of fibronectin in human colon cancer cells, CANCER RESEARCH, 74(19), 2014
  8. Regression of Cecal MALT Lymphoma after Antibiotic Treatment in a Patient with Helicobacter pylori Infection, INTERNAL MEDICINE, 55(2), 135-139, 2016
  9. Treatment with regorafenib inhibits the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic nude mice model of colon cancer, CANCER RESEARCH, 75, 2015
  10. Inhibition of collagen receptor discoidin domain receptor-1 (DDR1) reduces colon cancer cell migration and metastasis, CANCER RESEARCH, 75, 2015
  11. Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma, CANCER SCIENCE, 107(5), 601-608, 2016
  12. Mesenchymal Stem Cells Induce Epithelial to Mesenchymal Transition in Colon Cancer Cells through Direct Cell-to-Cell Contact, NEOPLASIA, 19(5), 429-438, 2017
  13. Combination therapy using molecular-targeted drugs modulates tumor microenvironment and impairs tumor growth in renal cell carcinoma, CANCER MEDICINE, 6(10), 2308-2320, 2017
  14. Expression of SPARC is associated with poor prognosis in human colon cancer, CANCER SCIENCE, 109, 1029-1029, 2018
  15. Silencing of Discoidin Domain Receptor-1 (DDR1) Concurrently Inhibits Multiple Steps of Metastasis Cascade in Gastric Cancer, TRANSLATIONAL ONCOLOGY, 11(3), 575-584, 2018
  16. Early-stage serrated adenocarcinomas are divided into several molecularly distinct subtypes, PLOS ONE, 14(2), 20190220
  17. A Questionnaire Survey on the Sequence of Events Prior to Undergoing Colonoscopy: The Influence of the Behavioral Response after a Fecal Occult Blood Test on the Early Detection of Colorectal Cancer, INTERNAL MEDICINE, 58(11), 1541-1547, 2019
  18. Helicobacter suis infection is associated with nodular gastritis-like appearance of gastric mucosa-associated lymphoid tissue lymphoma, CANCER MEDICINE, 8(9), 4370-4379, 201908
  19. Genomic Characterization of Non-Invasive Differentiated-Type Gastric Cancer in the Japanese Population, CANCERS, 12(2), 202002
  20. Stromal reaction inhibitor and immune-checkpoint inhibitor combination therapy attenuates excluded-type colorectal cancer in a mouse model, CANCER LETTERS, 498, 111-120, 20210201
  21. Gastric mucosa-associated lymphoid tissue lymphoma in conjunction with multiple lymphomatous polyposis in the context of Helicobacter pylori and Helicobacter suis superinfection, CLINICAL JOURNAL OF GASTROENTEROLOGY, 14(2), 478-483, 202104
  22. Clinical usefulness of combination therapy with polidocanol injection and argon plasma coagulation for gastric antral vascular ectasia, JGH OPEN, 5(4), 465-469, 202104
  23. Mesenchymal stem cells induce tumor stroma formation and epithelial-mesenchymal transition through SPARC expression in colorectal cancer, ONCOLOGY REPORTS, 45(6), 202106
  24. Genomic Landscape of Early-stage Colorectal Neoplasia Developing From the Ulcerative Colitis Mucosa in the Japanese Population, INFLAMMATORY BOWEL DISEASES, 27(5), 686-696, 202105
  25. Involvement of non-Helicobacter pylori helicobacter infections in Helicobacter pylori-negative gastric MALT lymphoma pathogenesis and efficacy of eradication therapy, GASTRIC CANCER, 24(4), 937-945, 202107
  26. Role of tumor-associated macrophages at the invasive front in human colorectal cancer progression, CANCER SCIENCE, 112(7), 2692-2704, 202107
  27. Genomic analysis for the prediction of prognosis in small-bowel cancer, PLOS ONE, 16(5), 20210520
  28. Clinical Features and Genomic Characterization of Post-Colonoscopy Colorectal Cancer, CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 11(10), 202010