KAZUHIRO KOBUKE

Last Updated :2023/02/02

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medicine), Contributing Assistant Professor
E-mail
kazu-kobukehiroshima-u.ac.jp
Self-introduction
.Elucidation of the molecular mechanisms of aldosterone synthesis and tumor formation in aldosterone-producing adenomas, the cause of primary aldosteronism Establishment of a new regional healthcare system for diabetes utilizing ICT and IOT

Educational Activity

Course in Charge

  1. 2022, Undergraduate Education, Year, Clinical diagnosis and treatment I
  2. 2022, Undergraduate Education, Intensive, Practice of Medicine I
  3. 2022, Undergraduate Education, Intensive, Practice of Medicine II
  4. 2022, Undergraduate Education, First Semester, Internalz Medicine II

Research Activities

Academic Papers

  1. ★, Calneuron 1 Increased Ca2+ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing Adenoma., Hypertension, 71(1), 125-133, 201801
  2. Efficacy and safety of insulin degludec in Japanese patients with type 1 and type 2 diabetes: 24-week results from the observational study in routine clinical practice., Journal of diabetes investigation, 7(1), 2016
  3. Gonadotropin-Releasing Hormone Stimulate Aldosterone Production in a Subset of Aldosterone-Producing Adenoma., Medicine, 95(20), 2016
  4. Hypomethylation of CYP11B2 in Aldosterone-Producing Adenoma., Hypertension (Dallas, Tex. : 1979), 68(6), 2016
  5. Aberrant G protein-receptor expression is associated with DNA methylation in aldosterone-producing adenoma., Molecular and cellular endocrinology, 461, 2018
  6. Purkinje Cell Protein 4 Expression Is Associated With DNA Methylation Status in Aldosterone-Producing Adenoma., The Journal of clinical endocrinology and metabolism, 103(3), 2018
  7. Angiotensin 1-7 suppresses angiotensin II mediated aldosterone production via JAK/STAT signaling inhibition., The Journal of steroid biochemistry and molecular biology, 185, 2019
  8. Measurement of midnight ACTH levels is useful for the evaluation of midnight cortisol levels., Steroids, 140, 2018
  9. Activation of classical brown adipocytes in the adult human perirenal depot is highly correlated with PRDM16-EHMT1 complex expression., PloS one, 10(3), 2015

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI(Grant-in-Aid for Research Activity Start-up), 2017, 2018