KAZUAKI CHAYAMA

Last Updated :2023/09/05

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medical), Professor, Collaborative Research Laboratory
Web Site
E-mail
chayamahiroshima-u.ac.jp
Self-introduction
Since I became a Professor of the Faculty of Medicine, Hiroshima University, in September, 2000 and the head Professor of the Division of Gastroenterology of Hiroshima University Hospital in April 2002, our laboratory has evolved steadily as the result of the hard work of its doctors, staff and graduate students in the field of medical examination, education and research. We really appreciate the support of persons concerned with these activities.

Basic Information

Major Professional Backgrounds

  • 1986/04/01, National Public Officers Mutual Aid Association Federation, Clinical Fellow
  • 1981/05/01, Medical corporation Dojinkai, Clinical Fellow
  • 1996/07/01, same, Medical director
  • 2000/09/01, 2002/03/31, Hiroshima University, Faculty of Medicine, Professor
  • 2002/04/01, 2019/03/31, Hiroshima University, Graduate School of Biomedical Sciences, Professor
  • 2005/04/01, 2011/03/31, Hiroshima University, Hospital, Deputy Director
  • 2009/04/01, 2011/03/31, Hiroshima University, Vice Executive
  • 2011/04/01, 2015/03/31, Hiroshima University, Hospital, Director
  • 2012/04/01, 2015/03/31, Hiroshima University, Executive and Vice President
  • 2015/04/01, 2016/03/31, Hiroshima University, Special Assistant to the President

Educational Backgrounds

  • Hiroshima University, Faculty of Medicine, Japan, 1974/04, 1981/03

Academic Degrees

  • Doctor of Philosophy in Medical Sciences, The University of Tokyo

In Charge of Primary Major Programs

  • Dentistry
  • Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Gastroenterology

Research Keywords

  • nucleotide sequence|Hepatitis-B
  • epigenetics
  • liver cirrhosis
  • driver mutation
  • deep sequence
  • whole genome analysisi
  • Hepatitis-C
  • whole genome sequencing
  • hepatitis
  • hepatocellular carcinoma

Affiliated Academic Societies

Research Activities

Academic Papers

  1. Untying relaxed circular DNA of hepatitis B virus by polymerase reaction provides a new option for accurate quantification and visualization of covalently closed circular DNA, JOURNAL OF GENERAL VIROLOGY, 103(2), 2022
  2. The importance of body composition assessment for patients with advanced hepatocellular carcinoma by bioelectrical impedance analysis in lenvatinib treatment, PLOS ONE, 17(1), 20220118
  3. Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease, SCIENCE TRANSLATIONAL MEDICINE, 14(650), 20220622
  4. White blood cell count is not associated with flow-mediated vasodilation or nitroglycerine-induced vasodilation, SCIENTIFIC REPORTS, 12(1), 20220517
  5. Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population, HUMAN MOLECULAR GENETICS, 26(3), 650-659, 20170201
  6. Quasispecies of Hepatitis C Virus Participate in Cell-Specific Infectivity, SCIENTIFIC REPORTS, 7, 20170322
  7. Long-term outcomes after endoscopic submucosal dissection for superficial colorectal tumors, GASTROINTESTINAL ENDOSCOPY, 85(3), 546-553, 201703
  8. Real-world efficacy and safety of daclatasvir and asunaprevir therapy for hepatitis C virus-infected cirrhosis patients, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 32(3), 645-650, 201703
  9. Endothelial dysfunction and abnormal vascular structure are simultaneously present in patients with heart failure with preserved ejection fraction, INTERNATIONAL JOURNAL OF CARDIOLOGY, 231, 181-187, 20170315
  10. Endothelial function is impaired in relation to alcohol intake even in the case of light alcohol consumption in Asian men; Flow-mediated Dilation Japan (FMD-J) Study, INTERNATIONAL JOURNAL OF CARDIOLOGY, 230, 523-528, 20170301
  11. IFNL4 polymorphism effects on outcome of simeprevir, peginterferon, and ribavirin therapy for older patients with genotype 1 chronic hepatitis C, HEPATOLOGY RESEARCH, 47(3), E5-E13, 201703
  12. Safety and efficacy of dual therapy with daclatasvir and asunaprevir for older patients with chronic hepatitis C, JOURNAL OF GASTROENTEROLOGY, 52(4), 504-511, 201704
  13. The combination of elbasvir and grazoprevir for the treatment of chronic HCV infection in Japanese patients: a randomized phase II/III study, JOURNAL OF GASTROENTEROLOGY, 52(4), 520-533, 201704
  14. Individual patient data meta-analysis of controlled attenuation parameter (CAP) technology for assessing steatosis, JOURNAL OF HEPATOLOGY, 66(5), 1022-1030, 201705
  15. Choline Deficiency Causes Colonic Type II Natural Killer T (NKT) Cell Loss and Alleviates Murine Colitis under Type I NKT Cell Deficiency, PLOS ONE, 12(1), 20170117
  16. Whole genome sequencing discriminates hepatocellular carcinoma with intrahepatic metastasis from multi-centric tumors, JOURNAL OF HEPATOLOGY, 66(2), 363-373, 201702
  17. Evaluation for the Clinical Efficacy of Colon Capsule Endoscopy in the Detection of Laterally Spreading Tumors, DIGESTION, 95(1), 43-48, 2017
  18. The practical management of chronic hepatitis C infection in Japan - dual therapy of daclatasvir plus asunaprevir, EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 11(2), 103-113, 201702
  19. Interferon Stimulated Genes and Innate Immune Activation Following Infection With Hepatitis B and C Viruses, JOURNAL OF MEDICAL VIROLOGY, 89(3), 388-396, 201703
  20. Efficacy and Safety of Daclatasvir Plus Asunaprevir Therapy for Chronic Hepatitis C Patients With Renal Dysfunction, JOURNAL OF MEDICAL VIROLOGY, 89(4), 665-671, 201704
  21. Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus, PLOS ONE, 12(3), 20170302
  22. Retrograde venography during balloon-occluded retrograde transvenous obliteration of gastric varices, MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES, 26(1), 1-6, 2017
  23. The relationship between HBcrAg and HBV reinfection in HBV related post-liver transplantation patients, JOURNAL OF GASTROENTEROLOGY, 52(3), 366-375, 201703
  24. The risk of transient postprandial oxyhypoglycemia in nonalcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 52(2), 253-262, 201702
  25. Daclatasvir/asunaprevir/beclabuvir fixed-dose combination in Japanese patients with HCV genotype 1 infection, JOURNAL OF GASTROENTEROLOGY, 52(3), 385-395, 201703
  26. Clinical impact and characteristics of the narrow-band imaging magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team, GASTROINTESTINAL ENDOSCOPY, 85(4), 816-821, 201704
  27. Mesenchymal Stem Cells Induce Epithelial to Mesenchymal Transition in Colon Cancer Cells through Direct Cell-to-Cell Contact, NEOPLASIA, 19(5), 429-438, 201705
  28. Clinical Usefulness of the VS Classification System Using Magnifying Endoscopy with Blue Laser Imaging for Early Gastric Cancer, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2017
  29. Why highly effective drugs are not enough: the need for an affordable solution to eliminating HCV, EXPERT REVIEW OF CLINICAL PHARMACOLOGY, 10(6), 583-594, 2017
  30. Increasing Risk of Osteoporotic Fracture Is Associated With Vascular Dysfunction and Abnormal Vascular Structure in Both Men and Women, CIRCULATION JOURNAL, 81(6), 862-+, 201706
  31. ITPA polymorphism effects on decrease of hemoglobin during sofosbuvir and ribavirin combination treatment for chronic hepatitis C, JOURNAL OF GASTROENTEROLOGY, 52(6), 746-753, 201706
  32. Characterization of miR-122-independent propagation of HCV, PLOS PATHOGENS, 13(5), 201705
  33. Impact of Hepatitis C Virus Eradication on the Clinical Outcome of Patients with Hepatitis C Virus-Related Advanced Hepatocellular Carcinoma Treated with Sorafenib, ONCOLOGY, 92(6), 335-346, 2017
  34. Endoscopic findings of the gastric mucosa during long-term use of proton pump inhibitor - a multicenter study, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 52(8), 828-832, 2017
  35. Randomized Phase 3 Trial of Ombitasvir/Paritaprevir/Ritonavir and Ribavirin for Hepatitis C Virus Genotype 2-Infected Japanese Patients, ADVANCES IN THERAPY, 34(6), 1449-1465, 201706
  36. Development of a Novel Site-Specific Pegylated Interferon Beta for Antiviral Therapy of Chronic Hepatitis B Virus, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61(6), 201706
  37. Usefulness of humanized cDNA-uPA/SCID mice for the study of hepatitis B virus and hepatitis C virus virology, JOURNAL OF GENERAL VIROLOGY, 98(5), 1040-1047, 201705
  38. Clinical usefulness of magnifying endoscopy for non-ampullary duodenal tumors, ENDOSCOPY INTERNATIONAL OPEN, 5(4), E297-E302, 201704
  39. Indications for Small-bowel Capsule Endoscopy in Patients with Chronic Abdominal Pain, INTERNAL MEDICINE, 56(12), 1453-1457, 2017
  40. Relation of the Bilateral Earlobe Crease to Endothelial Dysfunction, AMERICAN JOURNAL OF CARDIOLOGY, 119(12), 1983-1988, 20170615
  41. Liver fibrosis assessment by FibroScan compared with pathological findings of liver resection specimen in hepatitis C infection, HEPATOLOGY RESEARCH, 47(8), 767-772, 201707
  42. Decreased frequency and duration of tooth brushing is a risk factor for endothelial dysfunction, INTERNATIONAL JOURNAL OF CARDIOLOGY, 241, 30-34, 20170815
  43. Patients with early recurrence of hepatocellular carcinoma have poor prognosis, HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL, 16(3), 279-288, 201706
  44. Serological Evaluation of Gastric Cancer Risk Based on Pepsinogen and Helicobacter pylori Antibody: Relationship to Endoscopic Findings, DIGESTION, 95(4), 314-318, 2017
  45. Significance of non-alcoholic fatty liver disease in Crohn's disease: A retrospective cohort study, HEPATOLOGY RESEARCH, 47(9), 872-881, 201708
  46. Clinical usefulness of transabdominal ultrasonography prior to patency capsule for suspected small-bowel strictures, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 51(3), 281-287, 20160303
  47. Novel pH-sensitive multifunctional envelope-type nanodevice for siRNA-based treatments for chronic HBV infection, JOURNAL OF HEPATOLOGY, 64(3), 547-555, 201603
  48. Computer-aided diagnosis of colorectal polyp histology by using a real-time image recognition system and narrow-band imaging magnifying colonoscopy, GASTROINTESTINAL ENDOSCOPY, 83(3), 643-649, 201603
  49. Long-term outcomes after treatment for T1 colorectal carcinoma, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 31(3), 571-578, 201603
  50. Effect of tenofovir disoproxil fumarate on drug-resistant HBV clones, JOURNAL OF INFECTION, 72(1), 91-102, 201601
  51. A Patient with CTLA-4 Haploinsufficiency Presenting Gastric Cancer, JOURNAL OF CLINICAL IMMUNOLOGY, 36(1), 28-32, 201601
  52. Randomized comparison of daclatasvir plus asunaprevir versus telaprevir plus peginterferon/ribavirin in Japanese hepatitis C virus patients, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(1), 14-22, 201601
  53. Analysis of Hepatitis C Virus Genotype 1b Resistance Variants in Japanese Patients Treated with Paritaprevir-Ritonavir and Ombitasvir, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 60(2), 1106-1113, 201602
  54. Early events in hepatitis B virus infection: From the cell surface to the nucleus, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(2), 302-309, 201602
  55. Elimination of HCV via a non-ISG-mediated mechanism by vaniprevir and BMS-788329 combination therapy in human hepatocyte chimeric mice, VIRUS RESEARCH, 213, 62-68, 20160202
  56. An Analysis of Surgical Treatment for the Spontaneous Rupture of Hepatocellular Carcinoma, DIGESTIVE SURGERY, 33(1), 43-50, 2016
  57. Regression of Cecal MALT Lymphoma after Antibiotic Treatment in a Patient with Helicobacter pylori Infection, INTERNAL MEDICINE, 55(2), 135-139, 2016
  58. Preoperative Biliary Drainage in Cases of Borderline Resectable Pancreatic Cancer Treated with Neoadjuvant Chemotherapy and Surgery, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2016
  59. Development of hepatocellular carcinoma in patients with hepatitis C virus infection who achieved sustained virological response following interferon therapy: A large-scale, long-term cohort study, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(5), 1009-1015, 201605
  60. TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis, NATURE COMMUNICATIONS, 7, 201605
  61. Perinatal Resveratrol Supplementation to Spontaneously Hypertensive Rat Dams Mitigates the Development of Hypertension in Adult Offspring, HYPERTENSION, 67(5), 1045-1052, 201605
  62. Condition of muscularis mucosae is a risk factor for lymph node metastasis in T1 colorectal carcinoma, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 28(4), 1269-1276, 201404
  63. Efficacy of probucol for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label pilot study, HEPATOLOGY RESEARCH, 44(4), 429-435, 201404
  64. Endoscopic features and management of diminutive colorectal submucosal invasive carcinoma, DIGESTIVE ENDOSCOPY, 26, 78-83, 201404
  65. Clinicopathologic features of hyperplastic/serrated polyposis syndrome in Japan, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(11), 1693-1698, 201311
  66. Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice, JOURNAL OF GASTROENTEROLOGY, 48(11), 1259-1270, 201311
  67. Utility of controlled attenuation parameter measurement for assessing liver steatosis in Japanese patients with chronic liver diseases, HEPATOLOGY RESEARCH, 43(11), 1182-1189, 201311
  68. Relationship between Narrow-Band Imaging Magnifying Observation and Pit Pattern Diagnosis in Colorectal Tumors, DIGESTION, 87(1), 53-58, 2013
  69. Replication Study of 15 Recently Published Loci for Body Fat Distribution in the Japanese Population, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 20(4), 336-350, 2013
  70. Impact of interleukin-28B genotype on in vitro and in vivo systems of hepatitis C virus replication, HEPATOLOGY RESEARCH, 42(9), 841-853, 201209
  71. Role of Natural Killer T Cells in the Mouse Colitis-Associated Colon Cancer Model, SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 75(1), 16-26, 201201
  72. Telaprevir with peginterferon and ribavirin for treatment-naive patients chronically infected with HCV of genotype 1 in Japan, JOURNAL OF HEPATOLOGY, 56(1), 78-84, 201201
  73. Toward the Establishment of a Prediction System for the Personalized Treatment of Chronic Hepatitis C, JOURNAL OF INFECTIOUS DISEASES, 205(2), 204-210, 20120115
  74. Clinical outcomes of endoscopic submucosal dissection for rectal tumor close to the dentate line, GASTROINTESTINAL ENDOSCOPY, 76(2), 444-450, 201208
  75. Severe necroinflammatory reaction caused by natural killer cell-mediated Fas/Fas ligand interaction and dendritic cells in human hepatocyte chimeric mouse, HEPATOLOGY, 56(2), 555-566, 201208
  76. Clinical outcomes of endoscopic submucosal dissection and endoscopic mucosal resection for laterally spreading tumors larger than 20 mm, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(4), 734-740, 201204
  77. Clinical features and prognosis in patients with hepatocellular carcinoma that developed after hepatitis C virus eradication with interferon therapy, JOURNAL OF GASTROENTEROLOGY, 46(6), 799-808, 201106
  78. Common Genetic Polymorphism of ITPA Gene Affects Ribavirin-Induced Anemia and Effect of Peg-Interferon Plus Ribavirin Therapy, JOURNAL OF MEDICAL VIROLOGY, 83(6), 1048-1057, 201106
  79. Cutaneous complications after transcatheter arterial treatment for hepatocellular carcinoma via the internal mammary artery: how to avoid this complication, JAPANESE JOURNAL OF RADIOLOGY, 29(5), 307-315, 201106
  80. Influence of the rs738409 polymorphism in patatin-like phospholipase 3 on the treatment efficacy of non-alcoholic fatty liver disease with type 2 diabetes mellitus, HEPATOLOGY RESEARCH, 46(3), E146-E153, 201603
  81. Evaluation of Antibiotic Use to Prevent Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Cholangitis, HEPATO-GASTROENTEROLOGY, 62(138), 417-424, 2015
  82. Differences in serum microRNA profiles in hepatitis B and C virus infection, JOURNAL OF INFECTION, 70(3), 273-287, 201503
  83. Emerging treatments for chronic hepatitis C, JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 114(3), 204-215, 201503
  84. Towards safer and appropriate application of endoscopic submucosal dissection for T1 colorectal carcinoma as total excisional biopsy: Future perspectives, DIGESTIVE ENDOSCOPY, 27(2), 216-222, 201501
  85. Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity, Nature Communications, 6, 201501
  86. Inverse Association of IL28B Genotype and Liver mRNA Expression of Genes Promoting or Suppressing Antiviral State, JOURNAL OF MEDICAL VIROLOGY, 83(9), 1597-1607, 201109
  87. Rapid Emergence of Telaprevir Resistant Hepatitis C Virus Strain from Wildtype Clone In Vivo, HEPATOLOGY, 54(3), 781-788, 201109
  88. Statins induce apoptosis and inhibit proliferation in cholangiocarcinoma cells, INTERNATIONAL JOURNAL OF ONCOLOGY, 39(3), 561-568, 201109
  89. Flow-mediated vasodilation is augmented in a corkscrew collateral artery compared with that in a native artery in patients with thromboangiitis obliterans (Buerger disease), JOURNAL OF VASCULAR SURGERY, 54(6), 1689-1697, 201112
  90. Low Prevalence of Helicobacter pylori-negative Gastric Cancer among Japanese, HELICOBACTER, 16(6), 415-419, 201112
  91. Quantitative analysis of colorectal lesions observed on magnified endoscopy images, JOURNAL OF GASTROENTEROLOGY, 46(12), 1382-1390, 201112
  92. Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis B virus infection for the fiscal year 2008 in Japan, HEPATOLOGY RESEARCH, 40(1), 1-7, 201001
  93. Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis C virus infection for the fiscal year 2008 in Japan, HEPATOLOGY RESEARCH, 40(1), 8-13, 201001
  94. Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease, ATHEROSCLEROSIS, 206(2), 604-610, 200910
  95. ★, Adoptive immunotherapy with liver allograft-derived lymphocytes induces anti-HCV activity after liver transplantation in humans and humanized mice, JOURNAL OF CLINICAL INVESTIGATION, 119(11), 3226-3235, 200911
  96. Involvement of Epithelial Cell Transforming Sequence-2 Oncoantigen in Lung and Esophageal Cancer Progression, CLINICAL CANCER RESEARCH, 15(1), 256-266, 20090101
  97. FDG positron emission tomography/computed tomography for the detection of extrahepatic metastases from hepatocellular carcinoma, HEPATOLOGY RESEARCH, 39(2), 134-142, 200902
  98. Morbidly obese patient with non-alcoholic steatohepatitis-related cirrhosis who died from sepsis caused by dental infection of Porphyromonas gingivalis: A case report, HEPATOLOGY RESEARCH, 46(3), E210-E215, 201603
  99. MicroRNAs as Biomarkers for Liver Disease and Hepatocellular Carcinoma, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 17(3), 201603
  100. Functional Behavior of NKp46-Positive Intrahepatic Natural Killer Cells Against Hepatitis C Virus Reinfection After Liver Transplantation, TRANSPLANTATION, 100(2), 355-364, 201602
  101. Mouse model of proximal colon-specific tumorigenesis driven by microsatellite instability-induced Cre-mediated inactivation of Apc and activation of Kras, JOURNAL OF GASTROENTEROLOGY, 51(5), 447-457, 201605
  102. Clinical significance and validity of the subclassification for colorectal laterally spreading tumor granular type, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(5), 973-979, 201605
  103. ★, Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer, NATURE GENETICS, 48(5), 500-+, 201605
  104. Change in Imaging Findings on Angiography-Assisted CT During Balloon-Occluded Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma, CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 39(6), 865-874, 201606
  105. Relationship between serum triglyceride levels and endothelial function in a large community-based study, ATHEROSCLEROSIS, 249, 70-75, 201606
  106. CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 23(3), 309-319, 2016
  107. Hepatocellular carcinoma in Japanese patients with nonalcoholic fatty liver disease and alcoholic liver disease: multicenter survey, JOURNAL OF GASTROENTEROLOGY, 51(6), 586-596, 201606
  108. Reduced Human alpha-defensin 6 in Noninflamed Jejunal Tissue of Patients with Crohn's Disease, INFLAMMATORY BOWEL DISEASES, 22(5), 1119-1128, 201605
  109. Polidocanol injection therapy for small-bowel hemangioma by using double-balloon endoscopy, GASTROINTESTINAL ENDOSCOPY, 84(1), 163-167, 201607
  110. Interleukin-34 as a fibroblast-derived marker of liver fibrosis in patients with non-alcoholic fatty liver disease, SCIENTIFIC REPORTS, 6, 20160701
  111. Clinical usefulness of a single-use splinting tube for poor endoscope operability in deep colonic endoscopic submucosal dissection, ENDOSCOPY INTERNATIONAL OPEN, 4(6), E614-E617, 201606
  112. Comparison of Outcome of Hepatic Arterial Infusion Chemotherapy and Sorafenib in Patients with Hepatocellular Carcinoma Refractory to Transcatheter Arterial Chemoembolization, ANTICANCER RESEARCH, 36(7), 3523-3529, 201607
  113. Long-term outcomes after treatment for pedunculated-type T1 colorectal carcinoma: a multicenter retrospective cohort study, JOURNAL OF GASTROENTEROLOGY, 51(7), 702-710, 201607
  114. Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus, PLOS PATHOGENS, 12(5), 201605
  115. Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma, CANCER SCIENCE, 107(5), 601-608, 201605
  116. HBV culture and infectious systems, HEPATOLOGY INTERNATIONAL, 10(4), 559-566, 201607
  117. ADH1B and ALDH2 are associated with metachronous SCC after endoscopic submucosal dissection of esophageal squamous cell carcinoma, CANCER MEDICINE, 5(7), 1397-1404, 201607
  118. Useful condition of chromoendoscopy with indigo carmine and acetic acid for identifying a demarcation line prior to endoscopic submucosal dissection for early gastric cancer, BMC GASTROENTEROLOGY, 16, 20160719
  119. Hepatitis C virus dynamics and cellular gene expression in uPA-SCID chimeric mice with humanized livers during intravenous silibinin monotherapy, JOURNAL OF VIRAL HEPATITIS, 23(9), 708-717, 201609
  120. Daclatasvir and asunaprevir treatment improves liver function parameters and reduces liver fibrosis markers in chronic hepatitis C patients, HEPATOLOGY RESEARCH, 46(8), 758-764, 201607
  121. Improvement of renal dysfunction in a patient with hepatitis C virus-related liver cirrhosis by daclatasvir and asunaprevir combination therapy: A case report, HEPATOLOGY RESEARCH, 46(9), 944-948, 201608
  122. A randomized, controlled study of peginterferon lambda-1a/ribavirin +/- daclatasvir for hepatitis C virus genotype 2 or 3, SPRINGERPLUS, 5, 20160819
  123. Nitroglycerine-induced vasodilation in coronary and brachial arteries in patients with suspected coronary artery disease, INTERNATIONAL JOURNAL OF CARDIOLOGY, 219, 312-316, 20160915
  124. Three patients treated with daclatasvir and asunaprevir for recurrent hepatitis C after liver transplantation: Case report, HEPATOLOGY RESEARCH, 46(7), 707-712, 201606
  125. RNA Exosome Complex Regulates Stability of the Hepatitis B Virus X-mRNA Transcript in a Non-stop-mediated (NSD) RNA Quality Control Mechanism, JOURNAL OF BIOLOGICAL CHEMISTRY, 291(31), 15958-15974, 20160729
  126. Preoperative Fluorine 18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography for Prediction of Microvascular Invasion in Small Hepatocellular Carcinoma, JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 40(4), 524-530, 2016
  127. Long-term prognosis after endoscopic submucosal dissection for early gastric cancer in super-elderly patients, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 30(10), 4321-4329, 201610
  128. Endoscopic submucosal dissection for anorectal tumor with hemorrhoids close to the dentate line: a multicenter study of Hiroshima GI Endoscopy Study Group, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 30(10), 4425-4431, 201610
  129. Risk factors for esophageal stenosis after entire circumferential endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 30(9), 4049-4056, 201609
  130. Clinical impact of dual red imaging in colorectal endoscopic submucosal dissection: a pilot study, THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 9(5), 679-683, 201609
  131. Serum YKL-40 as a marker of liver fibrosis in patients with non-alcoholic fatty liver disease, SCIENTIFIC REPORTS, 6, 20161014
  132. Characteristics of non-obese non-alcoholic fatty liver disease: Effect of genetic and environmental factors, HEPATOLOGY RESEARCH, 46(10), 1011-1018, 201609
  133. Pharmacokinetics, efficacy and safety of daclatasvir plus asunaprevir in dialysis patients with chronic hepatitis C: pilot study, JOURNAL OF VIRAL HEPATITIS, 23(11), 850-856, 201611
  134. Interferon-stimulated gene of 20 kDa protein (ISG20) degrades RNA of Hepatitis B virus to impede the replication of HBV in vitro and in vivo, ONCOTARGET, 7(42), 68179-68193, 20161018
  135. Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection, JOURNAL OF GASTROENTEROLOGY, 51(11), 1073-1080, 201611
  136. Highly multiplexed CRISPR-Cas9-nuclease and Cas9-nickase vectors for inactivation of hepatitis B virus, GENES TO CELLS, 21(11), 1253-1262, 201611
  137. Clinical usefulness of narrow band imaging magnifying colonoscopy for assessing ulcerative colitis-associated cancer/dysplasia, ENDOSCOPY INTERNATIONAL OPEN, 4(11), E1183-E1187, 201611
  138. Third-Generation Capsule Endoscopy Outperforms Second-Generation Based on the Detectability of Esophageal Varices, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2016
  139. Vaniprevir plus peginterferon alfa-2b and ribavirin in treatment-experienced Japanese patients with hepatitis C virus genotype 1 (GT1b) infection: Phase 3 studies, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(10), 1674-1683, 201610
  140. A comparison of 4-Fr with 5-Fr endoscopic nasopancreatic drainage catheters: A randomized, controlled trial, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(10), 1783-1789, 201610
  141. Risk stratification of ventricular fibrillation in Brugada syndrome using noninvasive scoring methods, HEART RHYTHM, 13(10), 1947-1954, 201610
  142. Effects of ITPA polymorphism on decrease of hemoglobin during simeprevir, peg-interferon, and ribavirin combination treatment for chronic hepatitis C, HEPATOLOGY RESEARCH, 46(12), 1256-1263, 201611
  143. Combination therapies with daclatasvir and asunaprevir on NS3-D168 mutated HCV in human hepatocyte chimeric mice, ANTIVIRAL THERAPY, 21(4), 307-315, 2016
  144. Vascular Function and Intima-media Thickness of a Leg Artery in Peripheral Artery Disease: A Comparison of Buerger Disease and Atherosclerotic Peripheral Artery Disease, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 23(11), 1261-1269, 2016
  145. Genetic variations of aldehyde dehydrogenase 2 and alcohol dehydrogenase 1B are associated with the etiology of atrial fibrillation in Japanese, JOURNAL OF BIOMEDICAL SCIENCE, 23, 20161207
  146. Circulating level of pigment epithelium-derived factor is associated with vascular function and structure: A cross-sectional study, INTERNATIONAL JOURNAL OF CARDIOLOGY, 225, 91-95, 20161215
  147. Hepatitis C virus treatment update - A new era of all-oral HCV treatment, ADVANCES IN DIGESTIVE MEDICINE, 3(4), 153-160, 201612
  148. Endothelial Function Assessed by Automatic Measurement of Enclosed Zone Flow-Mediated Vasodilation Using an Oscillometric Method Is an Independent Predictor of Cardiovascular Events, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 5(12), 201612
  149. Protease Inhibitor Resistance Remains Even After Mutant Strains Become Undetectable by Deep Sequencing, JOURNAL OF INFECTIOUS DISEASES, 214(11), 1687-1694, 20161201
  150. Common Variant Near HEY2 Has a Protective Effect on Ventricular Fibrillation Occurrence in Brugada Syndrome by Regulating the Repolarization Current, CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 9(1), 201601
  151. Complete response to short-term sorafenib treatment alone for hepatocellular carcinoma with bone, lymph node, and peritoneum metastases, HEPATOLOGY RESEARCH, 46(13), 1402-1408, 201612
  152. Association between variants in the interferon lambda 4 locus and substitutions in the hepatitis C virus non-structural protein 5A, JOURNAL OF HEPATOLOGY, 63(3), 554-563, 201509
  153. Pulverized konjac glucomannan ameliorates oxazolone-induced colitis in mice, EUROPEAN JOURNAL OF NUTRITION, 54(6), 959-969, 201509
  154. Comparison of hepatic arterial infusion chemotherapy versus sorafenib monotherapy in patients with advanced hepatocellular carcinoma, JOURNAL OF DIGESTIVE DISEASES, 16(9), 505-512, 201509
  155. Evaluation of dual-wavelength excitation autofluorescence imaging of colorectal tumours with a high-sensitivity CMOS imager: a cross-sectional study, BMC GASTROENTEROLOGY, 15, 20150902
  156. Human Cytotoxic T Lymphocyte-Mediated Acute Liver Failure and Rescue by Immunoglobulin in Human Hepatocyte Transplant TK-NOG Mice, JOURNAL OF VIROLOGY, 89(19), 10087-10096, 201510
  157. Rho-Associated Kinase Activity Is an Independent Predictor of Cardiovascular Events in Acute Coronary Syndrome, HYPERTENSION, 66(4), 892-899, 201510
  158. Diagnosis of Helicobacter pylori-induced gastritis by serum pepsinogen levels, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(10), 1473-1477, 201510
  159. Randomized phase 3 trial of ombitasvir/paritaprevir/ritonavir for hepatitis C virus genotype 1b-infected Japanese patients with or without cirrhosis, HEPATOLOGY, 62(4), 1037-1046, 201510
  160. Risk of bleeding after endoscopic submucosal dissection for colorectal tumors in patients with continued use of low-dose aspirin, JOURNAL OF GASTROENTEROLOGY, 50(10), 1041-1046, 201510
  161. Clinical utility of gadoxetate disodium-enhanced hepatic MRI for stereotactic body radiotherapy of hepatocellular carcinoma, JAPANESE JOURNAL OF RADIOLOGY, 33(10), 627-635, 201510
  162. HCV Drug Resistance Challenges in Japan: The Role of Pre-Existing Variants and Emerging Resistant Strains in Direct Acting Antiviral Therapy, VIRUSES-BASEL, 7(10), 5328-5342, 201510
  163. Treatment of hepatic amyloid light-chain amyloidosis with bortezomib and dexamethasone in a liver transplant patient, HEPATOLOGY RESEARCH, 45(10), E150-E155, 201510
  164. Long term persistence of NS5A inhibitor-resistant hepatitis C virus in patients who failed daclatasvir and asunaprevir therapy, JOURNAL OF MEDICAL VIROLOGY, 87(11), 1913-1920, 201511
  165. Usefulness of combining gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging and contrast-enhanced ultrasound for diagnosing the macroscopic classification of small hepatocellular carcinoma, EUROPEAN RADIOLOGY, 25(11), 3272-3281, 201511
  166. A novel noninvasive diagnostic method for nonalcoholic steatohepatitis using two glycobiomarkers, HEPATOLOGY, 62(5), 1433-1443, 201511
  167. Clinical usefulness of endocytoscopy in the remission stage of ulcerative colitis: a pilot study, JOURNAL OF GASTROENTEROLOGY, 50(11), 1087-1093, 201511
  168. Biphasic effect of alcohol intake on the development of fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 50(11), 1114-1123, 201511
  169. Elevation of Serum Levels of Advanced Glycation End Products in Patients With Non-B or Non-C Hepatocellular Carcinoma, JOURNAL OF CLINICAL LABORATORY ANALYSIS, 29(6), 480-484, 201511
  170. Sustained virological response to antiviral therapy improves survival rate in patients with recurrent hepatitis C virus infection after liver transplantation, HEPATOLOGY RESEARCH, 45(11), 1047-1054, 201511
  171. Eicosapentaenoic acid/arachidonic acid ratio as a possible link between non-alcoholic fatty liver disease and cardiovascular disease, HEPATOLOGY RESEARCH, 45(5), 533-539, 201505
  172. Novel Robust in Vitro Hepatitis B Virus Infection Model Using Fresh Human Hepatocytes Isolated from Humanized Mice, AMERICAN JOURNAL OF PATHOLOGY, 185(5), 1275-1285, 201505
  173. Randomized Trial of Interferon- and Ribavirin-Free Ombitasvir/Paritaprevir/Ritonavir in Treatment-Experienced Hepatitis C Virus-Infected Patients, HEPATOLOGY, 61(5), 1523-1532, 201505
  174. The effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(3), 619-627, 201503
  175. Disseminated carcinomatosis of the bone marrow originating from hepatocellular carcinoma. A case report, HEPATOLOGY RESEARCH, 45(6), 705-710, 201506
  176. Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis, HEPATOLOGY RESEARCH, 45(6), 656-662, 201506
  177. Role of 3-D conformal radiotherapy for major portal vein tumor thrombosis combined with hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma, HEPATOLOGY RESEARCH, 45(6), 607-617, 201506
  178. The Time Course of Dynamic Computed Tomographic Appearance of Radiation Injury to the Cirrhotic Liver Following Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma, PLOS ONE, 10(6), 20150611
  179. High Sustained Virologic Response to Daclatasvir Plus Asunaprevir in Elderly and Cirrhotic Patients with Hepatitis C Virus Genotype 1b Without Baseline NS5A Polymorphisms, ADVANCES IN THERAPY, 32(7), 637-649, 201507
  180. Major predictors of portal hypertensive enteropathy in patients with liver cirrhosis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(1), 124-130, 201501
  181. Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection, EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 9(1), 21-30, 201501
  182. Ratio of Serum Levels of AGEs to Soluble Form of RAGE Is a Predictor of Endothelial Function, DIABETES CARE, 38(1), 119-125, 201501
  183. A Computer System To Be Used With Laser-based Endoscopy for Quantitative Diagnosis of Early Gastric Cancer, JOURNAL OF CLINICAL GASTROENTEROLOGY, 49(2), 108-115, 201502
  184. Effect of prolonged administration of pegylated interferon/ribavirin therapy in genotypes 2a and 2b: Propensity score-matched analysis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(2), 337-344, 201502
  185. Emergence of resistant variants detected by ultra-deep sequencing after asunaprevir and daclatasvir combination therapy in patients infected with hepatitis C virus genotype 1, JOURNAL OF VIRAL HEPATITIS, 22(2), 158-165, 201502
  186. mTOR and PDGF Pathway Blockade Inhibits Liver Metastasis of Colorectal Cancer by Modulating the Tumor Microenvironment, AMERICAN JOURNAL OF PATHOLOGY, 185(2), 399-408, 201502
  187. Ribavirin dose reduction during telaprevir/ribavirin/peg-interferon therapy overcomes the effect of the ITPA gene polymorphism, JOURNAL OF VIRAL HEPATITIS, 22(2), 166-174, 201502
  188. The Association between Glyceraldehyde-Derived Advanced Glycation End-Products and Colorectal Cancer Risk, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 24(12), 1855-1863, 201512
  189. Factors associated with the effect of interferon-alpha sequential therapy in order to discontinue nucleoside/nucleotide analog treatment in patients with chronic hepatitis B, HEPATOLOGY RESEARCH, 45(12), 1195-1202, 201512
  190. Interobserver and intraobserver agreement for gastric mucosa atrophy, BMC GASTROENTEROLOGY, 15, 20150804
  191. Major predictors and management of small-bowel angioectasia, BMC GASTROENTEROLOGY, 15, 20150825
  192. Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection, SCIENCE TRANSLATIONAL MEDICINE, 7(282), 20150408
  193. Effect of Aldosterone-Producing Adenoma on Endothelial Function and Rho-Associated Kinase Activity in Patients With Primary Aldosteronism, HYPERTENSION, 65(4), 841-848, 201504
  194. Evaluation of early response to hepatic arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma using the combination of Response Evaluation Criteria in Solid Tumors and tumor markers, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(4), 726-732, 201504
  195. Risk factors and management of positive horizontal margin in early gastric cancer resected by en bloc endoscopic submucosal dissection, GASTRIC CANCER, 18(2), 332-338, 201504
  196. Stereotactic body radiotherapy for patients with small hepatocellular carcinoma ineligible for resection or ablation therapies, HEPATOLOGY RESEARCH, 45(4), 378-386, 201504
  197. Two Patients Treated With Simeprevir Plus Pegylated-Interferon and Ribavirin Triple Therapy for Recurrent Hepatitis C After Living Donor Liver Transplantation: Case Report, TRANSPLANTATION PROCEEDINGS, 47(3), 809-814, 201504
  198. Endoscopic Submucosal Dissection as Total Excisional Biopsy for Clinical T1 Colorectal Carcinoma, DIGESTION, 91(1), 64-69, 2015
  199. On-treatment low serum HBV RNA level predicts initial virological response in chronic hepatitis B patients receiving nucleoside analogue therapy, ANTIVIRAL THERAPY, 20(4), 369-375, 2015
  200. Successful Use of Adalimumab for Treating Pyoderma Gangrenosum with Ulcerative Colitis under Corticosteroid-tapering Conditions, INTERNAL MEDICINE, 54(17), 2167-2172, 2015
  201. A MAVS/TICAM-1-Independent Interferon-Inducing Pathway Contributes to Regulation of Hepatitis B Virus Replication in the Mouse Hydrodynamic Injection Model, JOURNAL OF INNATE IMMUNITY, 7(1), 47-58, 2015
  202. The Role of the Selective Arterial Secretagogue Injection Test for Non-Functional Pancreatic Neuroendocrine Tumor, JOURNAL OF THE PANCREAS, 16(6), 601-606, 201511
  203. Antibiotic prophylaxis for endoscopic retrograde chlangiopancreatography increases the detection rate of drug-resistant bacteria in bile, JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 21(9), 712-718, 201409
  204. Human microRNA hsa-miR-1231 suppresses hepatitis B virus replication by targeting core mRNA, JOURNAL OF VIRAL HEPATITIS, 21(9), E89-E97, 201409
  205. Interleukin 28B polymorphism predicts interferon plus ribavirin treatment outcome in patients with hepatitis C virus-related liver cirrhosis: A multicenter retrospective study in Japan, HEPATOLOGY RESEARCH, 44(9), 983-992, 201409
  206. Critical Role of Exogenous Nitric Oxide in ROCK Activity in Vascular Smooth Muscle Cells, PLOS ONE, 9(10), e109017, 20141003
  207. Case reports of portal vein thrombosis and bile duct stenosis after stereotactic body radiation therapy for hepatocellular carcinoma, HEPATOLOGY RESEARCH, 44(10), E273-E278, 201410
  208. New Insight Into the Enhanced Effect of Pegylated Interferon-alpha, HEPATOLOGY, 60(4), 1435-1437, 201410
  209. Differences in K-ras and mitochondrial DNA mutations and microsatellite instability between colorectal cancers of Vietnamese and Japanese patients, BMC GASTROENTEROLOGY, 14, 20141130
  210. Endocannabinoid CB1 antagonists inhibit hepatitis C virus production, providing a novel class of antiviral host-targeting agents, JOURNAL OF GENERAL VIROLOGY, 95, 2468-2479, 201411
  211. Hepatitis C Virus Core Protein Suppresses Mitophagy by Interacting with Parkin in the Context of Mitochondrial Depolarization, AMERICAN JOURNAL OF PATHOLOGY, 184(11), 3026-3039, 201411
  212. Two patients treated with pegylated interferon/ribavirin/telaprevir triple therapy for recurrent hepatitis C after living donor liver transplantation, HEPATOLOGY RESEARCH, 44(12), 1259-1264, 201411
  213. Type 2 diabetes mellitus is associated with the fibrosis severity in patients with nonalcoholic fatty liver disease in a large retrospective cohort of Japanese patients, JOURNAL OF GASTROENTEROLOGY, 49(11), 1477-1484, 201411
  214. Upper limit of normal serum alanine aminotransferase levels in Japanese subjects, HEPATOLOGY RESEARCH, 44(12), 1196-1207, 201411
  215. Effect of vitamin D supplementation on pegylated interferon/ribavirin therapy for chronic hepatitis C genotype 1b: a randomized controlled trial, JOURNAL OF VIRAL HEPATITIS, 21(5), 348-356, 201405
  216. Long-term outcome of patients with gastric varices treated by balloon-occluded retrograde transvenous obliteration, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29(5), 1035-1042, 201405
  217. Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease, JOURNAL OF HUMAN GENETICS, 59(5), 241-246, 201405
  218. Characteristic Features of Cholangiocarcinoma Complicating Primary Sclerosing Cholangitis, HEPATO-GASTROENTEROLOGY, 61(131), 567-573, 201405
  219. Efficacy and Safety of Sitagliptin for the Treatment of Nonalcoholic Fatty Liver Disease with Type 2 Diabetes Mellitus, HEPATO-GASTROENTEROLOGY, 61(130), 323-328, 2014
  220. A comparative study of 4 Fr versus 6 Fr nasobiliary drainage catheters: A randomized, controlled trial, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29(3), 653-659, 201403
  221. Aryl hydrocarbon receptor plays protective roles in ConA-induced hepatic injury by both suppressing IFN- expression and inducing IL-22, INTERNATIONAL IMMUNOLOGY, 26(3), 129-137, 201403
  222. Is It Possible to Discriminate Between Neoplastic and Nonneoplastic Lesions in Ulcerative Colitis by Magnifying Colonoscopy?, INFLAMMATORY BOWEL DISEASES, 20(3), 508-513, 201403
  223. Is small-bowel capsule endoscopy effective for diagnosis of esophagogastric lesions related to portal hypertension?, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29(3), 511-516, 201403
  224. Non-invasive liver fibrosis score calculated by combination of virtual touch tissue quantification and serum liver functional tests in chronic hepatitis C patients, HEPATOLOGY RESEARCH, 44(3), 280-287, 201403
  225. Non-invasive liver fibrosis score calculated by combination of virtual touch tissue quantification and serum liver functional tests in chronic hepatitis C patients, HEPATOLOGY RESEARCH, 44(3), 280-287, 201403
  226. Predictors of incomplete resection and perforation associated with endoscopic submucosal dissection for colorectal tumors, GASTROINTESTINAL ENDOSCOPY, 79(3), 427-435, 201403
  227. Transarterial Therapy of Hepatocellular Carcinoma Fed by the Right Renal Capsular Artery, JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 25(3), 389-395, 201403
  228. Long-Term Elimination of Hepatitis C Virus from Human Hepatocyte Chimeric Mice After Interferon-gamma Gene Transfer, HUMAN GENE THERAPY CLINICAL DEVELOPMENT, 25(1), 28-39, 20140301
  229. Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system, SCIENTIFIC REPORTS, 4, 20140623
  230. Daclatasvir Plus Asunaprevir for Chronic HCV Genotype 1b Infection, HEPATOLOGY, 59(6), 2083-2091, 201406
  231. IFNL4/IL-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population, JOURNAL OF GENERAL VIROLOGY, 95, 1297-1306, 201406
  232. Timing of radiological improvement after steroid therapy in patients with autoimmune pancreatitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 49(6), 727-733, 201406
  233. Association of polymorphisms in GCKR and TRIB1 with nonalcoholic fatty liver disease and metabolic syndrome traits, ENDOCRINE JOURNAL, 61(7), 683-689, 201407
  234. Borderline Ankle-Brachial Index Value of 0.91-0.99 Is Associated With Endothelial Dysfunction, CIRCULATION JOURNAL, 78(7), 1740-+, 201407
  235. Continued use of low-dose aspirin does not increase the risk of bleeding during or after endoscopic submucosal dissection for early gastric cancer, GASTRIC CANCER, 17(3), 489-496, 201407
  236. Percutaneous transvenous embolization for portosystemic shunts associated with encephalopathy: Long-term outcomes in 14 patients, HEPATOLOGY RESEARCH, 44(7), 740-749, 201407
  237. Relationship between nitroglycerine-induced vasodilation and clinical severity of peripheral artery disease, ATHEROSCLEROSIS, 235(1), 65-70, 201407
  238. Risk factors for delayed bleeding after endoscopic submucosal dissection for colorectal neoplasms, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 29(7), 877-882, 201407
  239. The association of insomnia with gastroesophageal reflux symptoms in biopsy-proven nonalcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 49(7), 1163-1174, 201407
  240. Pilot Study of Stereotactic Body Radiation Therapy Combined with Transcatheter Arterial Chemoembolization for Small Hepatocellular Carcinoma, HEPATO-GASTROENTEROLOGY, 61(129), 31-36, 2014
  241. The effect of respiratory-gated positron emission tomography/computed tomography in patients with pancreatic cancer, HELLENIC JOURNAL OF NUCLEAR MEDICINE, 17(1), 31-36, 2014
  242. Advanced Method for Evaluation of Gastric Cancer Risk By Serum Markers: Determination of True Low-Risk Subjects for Gastric Neoplasm, HELICOBACTER, 19(1), 1-8, 201402
  243. Clinical validity of the expanded criteria for endoscopic resection of undifferentiated-type early gastric cancer based on long-term outcomes, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 28(2), 639-647, 201402
  244. Serum asymmetric dimethylarginine levels are independently associated with procollagen III N-terminal peptide in nonalcoholic fatty liver disease patients, CLINICAL AND EXPERIMENTAL MEDICINE, 14(1), 45-51, 201402
  245. Clinical outcome and prognostic factors of patients with hepatocellular carcinoma and extrahepatic metastasis treated with sorafenib, HEPATOLOGY RESEARCH, 44(13), 1320-1328, 201412
  246. Impact of alloimmune T cell responses on hepatitis C virus replication in liver transplant recipients, HUMAN IMMUNOLOGY, 75(12), 1259-1267, 201412
  247. Interferon lambda 4 polymorphism affects on outcome of telaprevir, pegylated interferon and ribavirin combination therapy for chronic hepatitis C, HEPATOLOGY RESEARCH, 44(14), E447-E454, 201412
  248. Non-invasive assessment of liver steatosis in non-alcoholic fatty liver disease, HEPATOLOGY RESEARCH, 44(14), E420-E427, 201412
  249. Predictive value of the IFNL4 polymorphism on outcome of telaprevir, peginterferon, and ribavirin therapy for older patients with genotype 1b chronic hepatitis C, JOURNAL OF GASTROENTEROLOGY, 49(12), 1548-1556, 201412
  250. Quantitative Effect of Natural Killer-Cell Licensing on Hepatocellular Carcinoma Recurrence after Curative Hepatectomy, CANCER IMMUNOLOGY RESEARCH, 2(12), 1142-1147, 201412
  251. Integrated Analysis of Whole Genome and Transcriptome Sequencing Reveals Diverse Transcriptomic Aberrations Driven by Somatic Genomic Changes in Liver Cancers, PLOS ONE, 9(12), 20141219
  252. Smoking Cessation Reverses DNA Double-Strand Breaks in Human Mononuclear Cells, PLOS ONE, 9(8), 20140805
  253. Simple scoring system for predicting cirrhosis in nonalcoholic fatty liver disease, WORLD JOURNAL OF GASTROENTEROLOGY, 20(29), 10108-10114, 20140821
  254. Characteristic Epithelium with Low-Grade Atypia Appears on the Surface of Gastric Cancer after Successful Helicobacter pylori Eradication Therapy, HELICOBACTER, 19(4), 289-295, 201408
  255. Clinical outcomes of endoscopic submucosal dissection for superficial Barrett's adenocarcinoma, GASTROINTESTINAL ENDOSCOPY, 80(2), 239-245, 201408
  256. Clinical efficacy of combination therapy with ME3738 and pegylated interferon-alpha-2a in patients with hepatitis C virus genotype 1, HEPATOLOGY RESEARCH, 44(4), 410-419, 201404
  257. Nonalcoholic Fatty Liver Disease and Cardiovascular Disease, CURRENT PHARMACEUTICAL DESIGN, 20(14), 2403-2411, 201404
  258. Poor Oral Health, That Is, Decreased Frequency of Tooth Brushing, Is Associated With Endothelial Dysfunction, CIRCULATION JOURNAL, 78(4), 950-954, 201404
  259. Rho-Associated Kinase Activity Is a Predictor of Cardiovascular Outcomes, HYPERTENSION, 63(4), 856-864, 201404
  260. Ultradeep Sequencing Study of Chronic Hepatitis C Virus Genotype 1 Infection in Patients Treated with Daclatasvir, Peginterferon, and Ribavirin, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 58(4), 2105-2112, 201404
  261. Efficacy of telaprevir-based therapy for difficult-to-treat patients with genotype 2 chronic hepatitis C in Japan, HEPATOLOGY RESEARCH, 45(7), 745-754, 20140901
  262. A MAVS/TICAM-1-Independent Interferon-Inducing Pathway Contributes to Regulation of Hepatitis B Virus Replication in the Mouse Hydrodynamic Injection Model., J Innate Immun., 20140801
  263. Detection of nonpolypoid colorectal neoplasia using magnifying endoscopy in colonic inflammatory bowel disease., Gastrointest Endosc Clin N Am., 24(3), 405-17, 20140701
  264. IFNL4 polymorphism affects on outcome of telaprevir, peg-interferon and ribavirin combination therapy for chronic hepatitis C., Hepatol Res., 20140401
  265. On-treatment low serum HBV RNA level predicts initial virological response in chronic hepatitis B patients receiving nucleoside analogue therapy., Antivir Ther., 20140401
  266. Efficacy and safety of sitagliptin for the treatment of nonalcoholic fatty liver disease with type 2 diabetes mellitus., Hepatogastroenterology., 61(130), 323-328, 20140301
  267. Letter: Pitavastatin supplementation of PEG-IFN/ribavirin improves sustained virological response against HCV, Aliment Pharmacol Ther., 39(4), 443-4, 20140201
  268. Serum interleukin-6 associated with hepatocellular carcinoma risk: a nested case-control study, Int J Cancer, 134(1), 154-163, 20140101
  269. Ultra deep sequencing study of HCV genotype 1 in chronic hepatitis patients treated with daclatasvir, peg-interferon and ribavirin, Antimicrob Agents Chemother, 20140101
  270. A randomized trial of daclatasvir with peginterferon alfa-2b and ribavirin for HCV genotype 1 infection, ANTIVIRAL THERAPY, 19(5), 491-499, 2014
  271. Characteristics of Metachronous Gastric Tumors after Endoscopic Submucosal Dissection for Gastric Intraepithelial Neoplasms, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2014
  272. Comparison of Small-Bowel Mucosal Injury between Low-Dose Aspirin and Non-Aspirin Non-Steroidal Anti-Inflammatory Drugs: A Capsule Endoscopy Study, DIGESTION, 89(3), 225-231, 2014
  273. Hepatitis C Virus (HCV) Reactivation Caused by Steroid Therapy for Dermatomyositis, INTERNAL MEDICINE, 53(23), 2689-2693, 2014
  274. Occupational Radiation Exposure during Endoscopic Retrograde Cholangiopancreatography and Usefulness of Radiation Protective Curtains, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2014
  275. Telaprevir is effective given every 12 h at 750 mg with pegylated interferon-alpha 2b and ribavirin to Japanese patients with HCV-1b IL28B rs8099917 TT, ANTIVIRAL THERAPY, 19(3), 277-285, 2014
  276. Virological escape in HCV genotype-1-infected patients receiving daclatasvir plus ribavirin and peginterferon alfa-2a or alfa-2b, ANTIVIRAL THERAPY, 19(5), 479-490, 2014
  277. A Translational Study of Resistance Emergence Using Sequential Direct-Acting Antiviral Agents for Hepatitis C Using Ultra-Deep Sequencing, AMERICAN JOURNAL OF GASTROENTEROLOGY, 108(9), 1464-1472, 201309
  278. Clinical usefulness of classification by transabdominal ultrasonography for detection of small-bowel stricture, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 48(9), 1041-1047, 201309
  279. Noninvasive scoring systems in patients with nonalcoholic fatty liver disease with normal alanine aminotransferase levels, JOURNAL OF GASTROENTEROLOGY, 48(9), 1051-1060, 201309
  280. Risk factors for vertical incomplete resection in endoscopic submucosal dissection as total excisional biopsy for submucosal invasive colorectal carcinoma, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 28(9), 1247-1256, 201309
  281. Thromboxane A(2) Synthase Inhibitors Prevent Production of Infectious Hepatitis C Virus in Mice With Humanized Livers, GASTROENTEROLOGY, 145(3), 658-+, 201309
  282. Clinical outcomes of endoscopic submucosal dissection for early gastric cancer in patients with chronic kidney disease, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(10), 1632-1637, 201310
  283. Elevated expression of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 in primary sclerosing cholangitis: Implications for cholangiocarcinogenesis, INTERNATIONAL JOURNAL OF ONCOLOGY, 43(4), 1073-1079, 201310
  284. Serum HBV RNA and HBeAg are useful markers for the safe discontinuation of nucleotide analogue treatments in chronic hepatitis B patients, JOURNAL OF GASTROENTEROLOGY, 48(10), 1188-1204, 201310
  285. A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 441(1), 230-235, 20131108
  286. Glycemic Variability Is an Independent Predictive Factor for Development of Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease, PLOS ONE, 8(11), 20131106
  287. Genetic Analyses Reveal a Role for Vitamin D Insufficiency in HCV-Associated Hepatocellular Carcinoma Development, PLOS ONE, 8(5), 20130529
  288. A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region, JOURNAL OF HEPATOLOGY, 58(5), 875-882, 201305
  289. Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B, JOURNAL OF MEDICAL VIROLOGY, 85(5), 789-798, 201305
  290. Left atrial thickness under the catheter ablation lines in patients with paroxysmal atrial fibrillation: insights from 64-slice multidetector computed tomography, HEART AND VESSELS, 28(3), 360-368, 201305
  291. Quantitative identification of mucosal gastric cancer under magnifying endoscopy with flexible spectral imaging color enhancement, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(5), 841-847, 201305
  292. Risk analysis of submucosal invasive rectal carcinomas for lymph node metastasis to expand indication criteria for endoscopic resection, DIGESTIVE ENDOSCOPY, 25, 21-25, 201305
  293. Small Bowel Abnormalities in Patients with Compensated Liver Cirrhosis, DIGESTIVE DISEASES AND SCIENCES, 58(5), 1390-1396, 201305
  294. High Expression of Gastrin Receptor Protein in Injured Mucosa of Helicobacter pylori-Positive Gastritis, DIGESTIVE DISEASES AND SCIENCES, 58(3), 634-640, 201303
  295. Inhibition of hepatocellular carcinoma by PegIFN alpha-2a in patients with chronic hepatitis C: a nationwide multicenter cooperative study, JOURNAL OF GASTROENTEROLOGY, 48(3), 382-390, 201303
  296. Involvement of microRNA-224 in cell proliferation, migration, invasion, and anti-apoptosis in hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(3), 565-575, 201303
  297. Stereotactic body radiation therapy combined with transcatheter arterial chemoembolization for small hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(3), 530-536, 201303
  298. Surgical treatment for portosystemic encephalopathy in patients with liver cirrhosis: Occlusion of portosystemic shunt in combination with splenectomy, HEPATOLOGY RESEARCH, 43(3), 249-254, 201303
  299. Virological response and safety of 24-week telaprevir alone in Japanese patients infected with hepatitis C virus subtype 1b, JOURNAL OF VIRAL HEPATITIS, 20(3), 167-173, 201303
  300. Warning for unprincipled colorectal endoscopic submucosal dissection: Accurate diagnosis and reasonable treatment strategy, DIGESTIVE ENDOSCOPY, 25(2), 107-116, 201303
  301. Nitroglycerine-Induced Vasodilation for Assessment of Vascular Function A Comparison With Flow-Mediated Vasodilation, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 33(6), 1401-+, 201306
  302. Autologous Bone-Marrow Mesenchymal Stem Cell Implantation and Endothelial Function in a Rabbit Ischemic Limb Model, PLOS ONE, 8(7), 20130704
  303. Effectiveness of polaprezinc for low-dose aspirin-induced small-bowel mucosal injuries as evaluated by capsule endoscopy: a pilot randomized controlled study, BMC GASTROENTEROLOGY, 13, 20130704
  304. Combination therapies with NS5A, NS3 and NS5B inhibitors on different genotypes of hepatitis C virus in human hepatocyte chimeric mice, GUT, 62(7), 1055-1061, 201307
  305. Dynamic computed tomography appearance of tumor response after stereotactic body radiation therapy for hepatocellular carcinoma: How should we evaluate treatment effects?, HEPATOLOGY RESEARCH, 43(7), 717-727, 201307
  306. Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan, HUMAN GENETICS, 132(7), 783-792, 201307
  307. Outcome of endoscopic submucosal dissection for gastric neoplasm in relationship to endoscopic classification of submucosal fibrosis, GASTRIC CANCER, 16(3), 404-410, 201307
  308. Risk factors for the exacerbation of esophageal varices or portosystemic encephalopathy after sustained virological response with IFN therapy for HCV-related compensated cirrhosis, JOURNAL OF GASTROENTEROLOGY, 48(7), 847-855, 201307
  309. Interleukin-28B polymorphisms and hepatitis C virus clearance, GENOME MEDICINE, 5, 20130129
  310. Single-nucleotide polymorphisms in GALNT8 are associated with the response to interferon therapy for chronic hepatitis C, JOURNAL OF GENERAL VIROLOGY, 94, 81-89, 201301
  311. Treatment of chronic hepatitis C virus infection in Japan: update on therapy and guidelines, JOURNAL OF GASTROENTEROLOGY, 48(1), 1-12, 201301
  312. Endoscopic submucosal dissection for residual early gastric cancer after endoscopic submucosal dissection, GASTROINTESTINAL ENDOSCOPY, 77(2), 298-302, 201302
  313. Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer, INTERNATIONAL JOURNAL OF CANCER, 132(4), 813-823, 20130215
  314. Clinical outcome of sorafenib treatment in patients with advanced hepatocellular carcinoma refractory to hepatic arterial infusion chemotherapy, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(12), 1834-1841, 201312
  315. Combining Molecular Targeted Drugs to Inhibit Both Cancer Cells and Activated Stromal Cells in Gastric Cancer, NEOPLASIA, 15(12), 1391-1399, 201312
  316. sRAGE is associated with low waist circumference and Hb levels in NAFLD, CENTRAL EUROPEAN JOURNAL OF MEDICINE, 8(6), 830-834, 201312
  317. HLA-DQB1*03 Confers Susceptibility to Chronic Hepatitis C in Japanese: A Genome-Wide Association Study, PLOS ONE, 8(12), 20131220
  318. Relationship between flow-mediated vasodilation and cardiovascular risk factors in a large community-based study, HEART, 99(24), 1837-1842, 20131215
  319. Inferior vena cava tumor thrombus that directly infiltrated from paracaval lymph node metastases in a patient with recurrent hepatocellular carcinoma, WORLD JOURNAL OF SURGICAL ONCOLOGY, 11, 20130806
  320. A novel noninvasive and simple method for assessment of endothelial function: Enclosed zone flow-mediated vasodilation (ezFMD) using an oscillation amplitude measurement, ATHEROSCLEROSIS, 229(2), 324-330, 201308
  321. NUDT3 rs206936 is associated with body mass index in obese Japanese women, ENDOCRINE JOURNAL, 60(8), 991-1000, 201308
  322. A Nonsynonymous Polymorphism in Semaphorin 3A as a Risk Factor for Human Unexplained Cardiac Arrest with Documented Ventricular Fibrillation, PLOS GENETICS, 9(4), 201304
  323. Airway Stenting for Tracheal Obstruction Due to Lymph Node Metastasis of Hepatocellular Carcinoma, ANTICANCER RESEARCH, 33(4), 1761-1764, 201304
  324. Characteristic magnifying narrow-band imaging features of colorectal tumors in each growth type, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 28(4), 459-468, 201304
  325. Characterization of virologic escape in hepatitis C virus genotype 1b patients treated with the direct-acting antivirals daclatasvir and asunaprevir, JOURNAL OF HEPATOLOGY, 58(4), 646-654, 201304
  326. Dual oral therapy with daclatasvir and asunaprevir for patients with HCV genotype 1b infection and limited treatment options, JOURNAL OF HEPATOLOGY, 58(4), 655-662, 201304
  327. Flow-Mediated Vasodilation and Anatomical Variation of the Brachial Artery (Double Brachial Artery) in Healthy Subjects and Patients With Cardiovascular Disease, CIRCULATION JOURNAL, 77(4), 1073-1080, 201304
  328. Identification of a Functional Variant in the MICA Promoter Which Regulates MICA Expression and Increases HCV-Related Hepatocellular Carcinoma Risk, PLOS ONE, 8(4), 20130411
  329. The long-term outcome of patients with gastric varices treated by balloon-occluded retrograde transvenous obliteration, J Gastroenterol Hepatol, 29(5), 1035-1042, 20131201
  330. The upper limit of normal serum alanine aminotransferase levels in Japanese subjects, Hepatol Res, 20131201
  331. Availability of monitoring serum HBV DNA plus RNA during nucleot(s)ide analogue therapy, J Gastroenterol, 48(6), 779-780, 20130601
  332. Response., Gastrointest Endosc., 77, 973-974, 20130601
  333. Endoscopic assessment of colorectal cancer with superficial or deep submucosal invasion using magnifying colonoscopy., Clin Endosc., 46, 138-146, 20130301
  334. Response to "Treatment guidelines for HCV genotype 1: mono for low, triple for high, and dual for 'middle'?"., J Gastroenterol., 20130201
  335. Clinical Characteristics of Patients who Developed Hepatocellular Carcinoma after Hepatitis C Virus Eradication with Interferon Therapy: Current Status in Japan, INTERNAL MEDICINE, 52(24), 2701-2706, 2013
  336. Hyperuricemia is independently associated with endothelial dysfunction in postmenopausal women but not in premenopausal women, BMJ OPEN, 3(11), 2013
  337. Hypovascular Hepatic Nodules Showing Hypointense on the Hepatobiliary-Phase Image of Gd-EOB-DTPA-Enhanced MRI to Develop a Hypervascular Hepatocellular Carcinoma: A Nationwide Retrospective Study on Their Natural Course and Risk Factors, DIGESTIVE DISEASES, 31(5-6), 472-479, 2013
  338. Is Occult Obscure Gastrointestinal Bleeding a Definite Indication for Capsule Endoscopy? A Retrospective Analysis of Diagnostic Yield in Patients with Occult versus Overt Bleeding, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2013
  339. Interleukin-28B single nucleotide polymorphism of donors and recipients can predict viral response to pegylated interferon/ribavirin therapy in patients with recurrent hepatitis C after living donor liver transplantation, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(9), 1467-1472, 201209
  340. Intima-Media Thickness of Brachial Artery, Vascular Function, and Cardiovascular Risk Factors, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(9), 2295-+, 201209
  341. A randomized phase II trial of intra-arterial chemotherapy using SM-11355 (Miriplatin) for hepatocellular carcinoma, INVESTIGATIONAL NEW DRUGS, 30(5), 2015-2025, 201210
  342. Hepatitis B Virus-Specific miRNAs and Argonaute2 Play a Role in the Viral Life Cycle, PLOS ONE, 7(10), 20121016
  343. Bile Acid Promotes Intestinal Metaplasia and Gastric Carcinogenesis, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 21(11), 2101-2107, 201211
  344. Efficacy of rosuvastatin for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label, pilot study, HEPATOLOGY RESEARCH, 42(11), 1065-1072, 201211
  345. Increased insulinogenic index is an independent determinant of nonalcoholic fatty liver disease activity score in patients with normal glucose tolerance, DIGESTIVE AND LIVER DISEASE, 44(11), 935-939, 201211
  346. Safety and Feasibility of Diet-Treated Donors With Steatotic Livers at the Initial Consultation for Living-Donor Liver Transplantation, TRANSPLANTATION, 93(10), 1024-1030, 20120527
  347. A huge metastatic liver tumor from leiomyosarcoma of the inferior vena cava: report of a case, SURGERY TODAY, 42(5), 505-508, 201205
  348. Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography, JOURNAL OF HUMAN GENETICS, 57(5), 305-310, 201205
  349. Association of two polymorphisms of the IL28B gene with viral factors and treatment response in 1,518 patients infected with hepatitis C virus, JOURNAL OF GASTROENTEROLOGY, 47(5), 596-605, 201205
  350. CURRENT STATUS AND FUTURE PERSPECTIVES OF ENDOSCOPIC SUBMUCOSAL DISSECTION FOR COLORECTAL TUMORS, DIGESTIVE ENDOSCOPY, 24, 73-79, 201205
  351. Hepatic arterial infusion chemotherapy using 5-fluorouracil and systemic interferon-a for advanced hepatocellular carcinoma in combination with or without three-dimensional conformal radiotherapy to venous tumor thrombosis in hepatic vein or inferior vena, HEPATOLOGY RESEARCH, 42(5), 442-453, 201205
  352. Hepatocellular carcinoma: Towards personalized medicine, CANCER SCIENCE, 103(5), 846-850, 201205
  353. Prevalence and associated metabolic factors of nonalcoholic fatty liver disease in the general population from 2009 to 2010 in Japan: a multicenter large retrospective study, JOURNAL OF GASTROENTEROLOGY, 47(5), 586-595, 201205
  354. USEFULNESS AND SAFETY OF SB KNIFE JR IN ENDOSCOPIC SUBMUCOSAL DISSECTION FOR COLORECTAL TUMORS, DIGESTIVE ENDOSCOPY, 24, 90-95, 201205
  355. Value of Cytodiagnosis Using Endoscopic Nasopancreatic Drainage for Early Diagnosis of Pancreatic Cancer Establishing a New Method for the Early Detection of Pancreatic Carcinoma In Situ, PANCREAS, 41(4), 523-529, 201205
  356. A Genome-Wide Association Study of Nephrolithiasis in the Japanese Population Identifies Novel Susceptible Loci at 5q35.3, 7p14.3, and 13q14.1, PLOS GENETICS, 8(3), 201203
  357. Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders, HEPATOLOGY, 55(3), 742-748, 201203
  358. Serum screening for detection of high-risk group for early-stage diffuse type gastric cancer in Japanese, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(3), 598-602, 201203
  359. Treatment of chronic hepatitis B with nucleos(t)ide analogues, HEPATOLOGY RESEARCH, 42(3), 219-225, 201203
  360. Effect of urine pH changed by dietary intervention on uric acid clearance mechanism of pH-dependent excretion of urinary uric acid, NUTRITION JOURNAL, 11, 20120607
  361. Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-alpha-lowering property, DIGESTIVE AND LIVER DISEASE, 44(6), 492-496, 201206
  362. Diagnostic Yield of Capsule Endoscopy vs. Double-Balloon Endoscopy for Patients who have Undergone Total Enteroscopy with Obscure Gastrointestinal Bleeding, HEPATO-GASTROENTEROLOGY, 59(116), 955-959, 201206
  363. Management of T1 colorectal carcinoma with special reference to criteria for curative endoscopic resection, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(6), 1057-1062, 201206
  364. Hyperbilirubinemia, Augmentation of Endothelial Function, and Decrease in Oxidative Stress in Gilbert Syndrome, CIRCULATION, 126(5), 598-603, 20120731
  365. Follow up of the 987 blood donors found with hepatitis C virus infection over 9-18 years, HEPATOLOGY RESEARCH, 42(7), 637-647, 201207
  366. Genetics of IL28B and HCV-response to infection and treatment, NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 9(7), 406-417, 201207
  367. IL28B polymorphism is associated with fatty change in the liver of chronic hepatitis C patients, JOURNAL OF GASTROENTEROLOGY, 47(7), 834-844, 201207
  368. ★, Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators, NATURE GENETICS, 44(7), 760-U182, 201207
  369. Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population, BMC GASTROENTEROLOGY, 12, 20120105
  370. Clinical validity of endoscopic submucosal dissection for submucosal invasive gastric cancer: a single-center study, GASTRIC CANCER, 15(1), 97-105, 201201
  371. Computer-aided system for predicting the histology of colorectal tumors by using narrow-band imaging magnifying colonoscopy, GASTROINTESTINAL ENDOSCOPY, 75(1), 179-185, 201201
  372. Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women, JOURNAL OF HUMAN GENETICS, 57(1), 46-51, 201201
  373. Geranylgeranylacetone, Heat Shock Protein 90/AMP-Activated Protein Kinase/Endothelial Nitric Oxide Synthase/Nitric Oxide Pathway, and Endothelial Function in Humans, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(1), 153-U350, 201201
  374. Outcome of patients who have undergone total enteroscopy for obscure gastrointestinal bleeding, WORLD JOURNAL OF GASTROENTEROLOGY, 18(7), 666-672, 20120221
  375. Combination of hepatitis B viral antigens and DNA for prediction of relapse after discontinuation of nucleos(t)ide analogs in patients with chronic hepatitis B, HEPATOLOGY RESEARCH, 42(2), 139-149, 201202
  376. Efficacy and safety of telaprevir, a new protease inhibitor, for difficult-to-treat patients with genotype 1 chronic hepatitis C, JOURNAL OF VIRAL HEPATITIS, 19(2), E134-E142, 201202
  377. ★, Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor, NATURE MEDICINE, 18(2), 281-285, 201202
  378. Impact of Pegylated Interferon Therapy on Outcomes of Patients with Hepatitis C Virus-Related Hepatocellular Carcinoma After Curative Hepatic Resection, ANNALS OF SURGICAL ONCOLOGY, 19(2), 418-425, 201202
  379. Mineralocorticoid Receptor Blocker Eplerenone Improves Endothelial Function and Inhibits Rho-Associated Kinase Activity in Patients With Hypertension, CLINICAL PHARMACOLOGY & THERAPEUTICS, 91(2), 289-297, 201202
  380. Serum PAI-1 is a novel predictor for response to pegylated interferon-a-2b plus ribavirin therapy in chronic hepatitis C virus infection, JOURNAL OF VIRAL HEPATITIS, 19(2), E126-E133, 201202
  381. Chronic hepatitis B in patients coinfected with human immunodeficiency virus in Japan: a retrospective multicenter analysis, JOURNAL OF INFECTION AND CHEMOTHERAPY, 18(6), 883-890, 201212
  382. Clinical features of pharyngeal intraepithelial neoplasias and outcomes of treatment by endoscopic submucosal dissection, GASTROINTESTINAL ENDOSCOPY, 76(6), 1095-1103, 201212
  383. Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma according to Child-Pugh classification, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(12), 1850-1857, 201212
  384. Serum levels of pigment epithelium-derived factor (PEDF) are independently associated with procollagen III N-terminal peptide levels in patients with nonalcoholic fatty liver disease, CLINICAL BIOCHEMISTRY, 45(18), 1554-1557, 201212
  385. Microvascular structure and perfusion imaging of colon cancer by means of contrast-enhanced ultrasonography, ABDOMINAL IMAGING, 37(2), 297-303, 201204
  386. Recent trend of clinical features in patients with hepatocellular carcinoma, HEPATOLOGY RESEARCH, 42(4), 368-375, 201204
  387. Migration to the pulmonary artery of nine metallic coils placed in the internal iliac vein for treatment of giant rectal varices., Acta Radiol, 1(6), 20120701
  388. Long-Term Outcomes of Hepatic Arterial Port Implantation using a Coaxial Microcatheter System in 176 Patients with Hepatocellular Carcinoma., 61(1), 7-13, 20120301
  389. Compliance with standard precautions among gastrointestinal endoscopists and endoscopy nurses in Japan., Am J Infect Control., 40, 80, 20120201
  390. Regression of rectal MALT lymphoma after antibiotic treatment in a patient negative for Helicobacter pylori, Clin J Gastroenterol, 5(1), 59-63, 20120201
  391. Removal of a sewing needle penetrating the wall of the third portion of the duodenum by double- balloon endoscopy, Clin J Gastroenterol, 5(1), 79-81, 20120201
  392. Change in malpractice claims in Japanese gastroenterological practice, Am J Gastroenterol, 107(1), 143-144, 20120101
  393. Achievement of Sustained Viral Response after Switching Treatment from Pegylated Interferon alpha-2b to alpha-2a and Ribavirin in Patients with Recurrence of Hepatitis C Virus Genotype 1 Infection after Liver Transplantation: A Case Report, INTERVIROLOGY, 55(4), 306-310, 2012
  394. Amino Acid Substitution in HCV Core Region and Genetic Variation near the IL28B Gene Affect Viral Dynamics during Telaprevir, Peginterferon and Ribavirin Treatment, INTERVIROLOGY, 55(6), 417-425, 2012
  395. Amino Acid Substitution in HCV Core/NS5A Region and Genetic Variation Near IL28B Gene Affect Treatment Efficacy to Interferon plus Ribavirin Combination Therapy, INTERVIROLOGY, 55(3), 231-241, 2012
  396. Evaluation of Individual Risk in Nonvariceal Gastrointestinal Bleeding Patients with NSAID Administration: A Multicenter Study in Japan, DIGESTION, 86(3), 187-193, 2012
  397. Evaluation of the mRECIST and alpha-Fetoprotein Ratio for Stratification of the Prognosis of Advanced-Hepatocellular-Carcinoma Patients Treated with Sorafenib, ONCOLOGY, 83(4), 192-200, 2012
  398. Gastric Cancer Development after Helicobacter pylori Eradication Therapy: A New Form of Gastric Neoplasia, DIGESTION, 85(1), 61-67, 2012
  399. Identification of novel HCV deletion mutants in chronic hepatitis C patients, ANTIVIRAL THERAPY, 17(8), 1551-1561, 2012
  400. Helicobacter pylori cagA polymorphism and gastric inflammation: An international comparison between Japanese and Brazilian patients, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 46(9), 1051-1056, 201109
  401. Impact of Viral Amino Acid Substitutions and Host Interleukin-28B Polymorphism on Replication and Susceptibility to Interferon of Hepatitis C Virus, HEPATOLOGY, 54(3), 764-771, 201109
  402. Improved detectability of small-bowel lesions via capsule endoscopy with computed virtual chromoendoscopy: A pilot study, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 46(9), 1133-1137, 201109
  403. Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area, JOURNAL OF HUMAN GENETICS, 56(10), 716-719, 201110
  404. Frequent somatic mutations of mitochondrial DNA in traditional serrated adenomas but not in sessile serrated adenomas of the colorectum, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 26(10), 1565-1569, 201110
  405. IL28B polymorphism may guide pegylated interferon plus ribavirin therapy even after curative treatment for hepatitis C virus-related hepatocellular carcinoma, JOURNAL OF VIRAL HEPATITIS, 18(10), E550-E560, 201110
  406. Lymphocyte subset characterization associated with persistent hepatitis C virus infection and subsequent progression of liver fibrosis, HUMAN IMMUNOLOGY, 72(10), 821-826, 201110
  407. Prevention of hepatitis B virus reactivation in immunosuppressive therapy or chemotherapy, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 15(5), 634-640, 201110
  408. Rho-Associated Kinase Activity, Endothelial Function, and Cardiovascular Risk Factors, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 31(10), 2353-2359, 201110
  409. RISK FACTORS FOR BLEEDING AFTER ENDOSCOPIC SUBMUCOSAL DISSECTION OF GASTRIC EPITHELIAL NEOPLASM, DIGESTIVE ENDOSCOPY, 23(4), 290-295, 201110
  410. A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population, HUMAN MOLECULAR GENETICS, 20(19), 3884-3892, 20111001
  411. Assessment of Trypsinogen-2 Levels as an Early Diagnostic for Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis, PANCREAS, 40(8), 1206-1210, 201111
  412. Clinical outcome of esophageal varices after hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with major portal vein tumor thrombus, HEPATOLOGY RESEARCH, 41(11), 1046-1056, 201111
  413. Eradication of hepatitis C virus genotype 1 after liver transplantation by interferon therapy before surgery: Report of three patients with analysis of interleukin-28 polymorphism, hepatitis C virus core region and interferon-sensitivity determining regio, HEPATOLOGY RESEARCH, 41(11), 1126-1131, 201111
  414. Platelet count for predicting fibrosis in nonalcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 46(11), 1300-1306, 201111
  415. The Water-Soluble Extract from Cultured Medium of Ganoderma lucidum (Reishi) Mycelia (Designated as MAK) Ameliorates Murine Colitis Induced by Trinitrobenzene Sulphonic Acid, SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 74(5), 454-462, 201111
  416. CLINICAL USEFULNESS OF NARROW BAND IMAGING MAGNIFYING CLASSIFICATION FOR COLORECTAL TUMORS BASED ON BOTH SURFACE PATTERN AND MICROVESSEL FEATURES, DIGESTIVE ENDOSCOPY, 23, 101-105, 201105
  417. Elimination of hepatitis C virus by short term NS3-4A and NS5B inhibitor combination therapy in human hepatocyte chimeric mice, JOURNAL OF HEPATOLOGY, 54(5), 872-878, 201105
  418. IL-28B predicts response to chronic hepatitis C therapy - fine-mapping and replication study in Asian populations, JOURNAL OF GENERAL VIROLOGY, 92, 1071-1081, 201105
  419. Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model, INTERNATIONAL JOURNAL OF CANCER, 128(9), 2050-2062, 20110501
  420. Plaunotol Induces a Comparative Increase of Acidic Mucin Fraction in Gastric Juice, HEPATO-GASTROENTEROLOGY, 58(106), 663-668, 2011
  421. Prevalence and impact of musculoskeletal pain in Japanese gastrointestinal endoscopists: A controlled study, WORLD JOURNAL OF GASTROENTEROLOGY, 17(11), 1488-1493, 20110321
  422. Impaired gastric response to modified sham feeding in patients with postprandial distress syndrome, NEUROGASTROENTEROLOGY AND MOTILITY, 23(3), 201103
  423. Possibility of Adoptive Immunotherapy With Peripheral Blood-derived CD3(-)CD56(+) and CD3(+)CD56(+) Cells for Inducing Antihepatocellular Carcinoma and Antihepatitis C Virus Activity, JOURNAL OF IMMUNOTHERAPY, 34(2), 137-146, 201103
  424. Postprandial insulin secretion pattern is associated with histological severity in non-alcoholic fatty liver disease patients without prior known diabetes mellitus, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 26(3), 517-522, 201103
  425. Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b, JOURNAL OF HEPATOLOGY, 54(3), 408-414, 201103
  426. Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model, JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 48(2), 161-166, 20110302
  427. IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy, JOURNAL OF HEPATOLOGY, 54(6), 1094-1101, 201106
  428. Prediction of Response to Peginterferon-Alfa-2b Plus Ribavirin Therapy in Japanese Patients Infected With Hepatitis C Virus Genotype 1b, JOURNAL OF MEDICAL VIROLOGY, 83(6), 981-988, 201106
  429. Antiviral effects of peginterferon alpha-2b and ribavirin following 24-week monotherapy of telaprevir in Japanese hepatitis C patients, JOURNAL OF GASTROENTEROLOGY, 46(7), 929-937, 201107
  430. Impact of ribavirin dose reduction on the efficacy of pegylated interferon plus ribavirin combination therapy for elderly patients infected with genotype 1b and high viral loads, HEPATOLOGY RESEARCH, 41(7), 626-634, 201107
  431. ME3738 enhances the effect of interferon and inhibits hepatitis C virus replication both in vitro and in vivo, JOURNAL OF HEPATOLOGY, 55(1), 11-18, 201107
  432. Effects of Hepatitis B Virus Infection on the Interferon Response in Immunodeficient Human Hepatocyte Chimeric Mice, JOURNAL OF INFECTIOUS DISEASES, 204(2), 224-228, 20110715
  433. IL28B But Not ITPA Polymorphism Is Predictive of Response to Pegylated Interferon, Ribavirin, and Telaprevir Triple Therapy in Patients With Genotype 1 Hepatitis C, JOURNAL OF INFECTIOUS DISEASES, 204(1), 84-93, 20110701
  434. Treatment Strategy for Early Hepatocellular Carcinomas: Comparison of Radiofrequency Ablation With or Without Transcatheter Arterial Chemoembolization and Surgical Resection, JOURNAL OF SURGICAL ONCOLOGY, 104(1), 3-9, 20110701
  435. Animal model for study of human hepatitis viruses, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 26(1), 13-18, 201101
  436. Hepatitis C virus: How genetic variability affects pathobiology of disease, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 26, 83-95, 201101
  437. Management of hepatitis B: Consensus of the Japan Society of Hepatology 2009, HEPATOLOGY RESEARCH, 41(1), 1-21, 201101
  438. Measurement of Rho-associated kinase (ROCK) activity in humans: Validity of leukocyte p-MBS/t-MBS in comparison with vascular response to fasudil, ATHEROSCLEROSIS, 214(1), 117-121, 201101
  439. Vascular Function and Circulating Progenitor Cells in Thromboangitis Obliterans (Buerger's Disease) and Atherosclerosis Obliterans, HYPERTENSION, 57(1), 70-U204, 201101
  440. A simple clinical scoring system using ferritin, fasting insulin, and type IV collagen 7S for predicting steatohepatitis in nonalcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 46(2), 257-268, 201102
  441. Advantages of endoscopic submucosal dissection versus endoscopic oblique aspiration mucosectomy for superficial esophageal tumors, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 26(2), 275-280, 201102
  442. Autologous Bone-Marrow Mononuclear Cell Implantation Reduces Long-Term Major Amputation Risk in Patients With Critical Limb Ischemia A Comparison of Atherosclerotic Peripheral Arterial Disease and Buerger Disease, CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 4(1), 15-25, 201102
  443. Calcium channel blocker and Rho-associated kinase activity in patients with hypertension, JOURNAL OF HYPERTENSION, 29(2), 373-379, 201102
  444. Genetic pathways of multiple esophageal squamous cell carcinomas, ONCOLOGY REPORTS, 25(2), 453-459, 201102
  445. HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy, GUT, 60(2), 261-267, 201102
  446. Improved visibility of lesions of the small intestine via capsule endoscopy with computed virtual chromoendoscopy, GASTROINTESTINAL ENDOSCOPY, 73(2), 299-306, 201102
  447. Influence of ITPA Polymorphisms on Decreases of Hemoglobin During Treatment with Pegylated Interferon, Ribavirin, and Telaprevir, HEPATOLOGY, 53(2), 415-421, 201102
  448. Hepatitis C Virus Infection Suppresses the Interferon Response in the Liver of the Human Hepatocyte Chimeric Mouse, PLOS ONE, 6(8), 20110823
  449. In Vivo Adaptation of Hepatitis C Virus in Chimpanzees for Efficient Virus Production and Evasion of Apoptosis, HEPATOLOGY, 54(2), 425-433, 201108
  450. ★, Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers, NATURE GENETICS, 43(8), 797-U108, 201108
  451. A single nucleotide polymorphism in activated cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients, JOURNAL OF HEPATOLOGY, 54(4), 629-639, 201104
  452. Factors predictive of sustained virological response following 72 weeks of combination therapy for genotype 1b hepatitis C, JOURNAL OF GASTROENTEROLOGY, 46(4), 545-555, 201104
  453. Impact of Radiation and Hepatitis Virus Infection on Risk of Hepatocellular Carcinoma, HEPATOLOGY, 53(4), 1237-1245, 201104
  454. Absence of viral interference and different susceptibility to interferon between hepatitis B virus and hepatitis C virus in human hepatocyte chimeric mice, JOURNAL OF HEPATOLOGY, 51(6), 1046-1054, 200912
  455. Detection of Helicobacter hepaticus in Human Bile Samples of Patients with Biliary Disease, HELICOBACTER, 14(6), 545-551, 200912
  456. Effects of structural variations of APOBEC3A and APOBEC3B genes in chronic hepatitis B virus infection, HEPATOLOGY RESEARCH, 39(12), 1159-1168, 200912
  457. Presence of Poorly Differentiated Component Correlated with Submucosal Invasion in the Early Diffuse-type Gastric Cancer, HEPATO-GASTROENTEROLOGY, 55(88), 2264-2268, 2008
  458. Aging and Hypertension Are Independent Risk Factors for Reduced Number of Circulating Endothelial Progenitor Cells, AMERICAN JOURNAL OF HYPERTENSION, 21(11), 1203-1209, 200811
  459. Vascular Endothelial Growth Factor C Stimulates Progression of Human Gastric Cancer via Both Autocrine and Paracrine Mechanisms, CLINICAL CANCER RESEARCH, 14(22), 7205-7214, 20081115
  460. Usefulness of EUS with double-balloon enteroscopy for diagnosis of small-bowel diseases, GASTROINTESTINAL ENDOSCOPY, 65(3), 412-420, 200703
  461. Clinical significance of mucosal suppressors of cytokine signaling 3 expression in ulcerative colitis, WORLD JOURNAL OF GASTROENTEROLOGY, 13(21), 2939-2944, 20070607
  462. Magnifying endoscopy with narrow band imaging for diagnosis of colorectal tumors, GASTROINTESTINAL ENDOSCOPY, 65(7), 988-995, 200706
  463. Reduced expression of heme oxygenase-1 in patients with coronary atherosclerosis, HYPERTENSION RESEARCH, 30(4), 341-348, 200704
  464. Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 49(4), 221-227, 200704
  465. Primary follicular lymphoma of the gastrointestinal tract: a retrospective case series, Endoscopy, 20071201
  466. Images in cardiovascular medicine. Corkscrew collaterals in thromboangitis obliterans (Buerger's disease)., CIRCULATION, E539-E540, 20071120
  467. Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 50(11), 3867-3874, 200611
  468. Medical malpractice litigation related to gastrointestinal endoscopy in Japan: A two-decade review of civil court cases, WORLD JOURNAL OF GASTROENTEROLOGY, 12(42), 6857-6860, 20061114
  469. Surface structure of antral gastric mucosa represents the status of histologic gastritis: Fundamental evidence for the evaluation of antral gastritis by magnifying endoscopy, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 21(5), 837-841, 200605
  470. Single nucleotide polymorphism in the hypoxia-inducible factor-1 alpha gene in colorectal carcinoma, ONCOLOGY REPORTS, 12(5), 1033-1037, 200411
  471. A single nucleotide polymorphism in the MMP-1 promoter is correlated with histological differentiation of gastric cancer, JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 130(5), 259-265, 200405
  472. Matrix metalloproteinase-9 contributes to human atrial remodeling during atrial fibrillation, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 43(5), 818-825, 20040303
  473. The specific expression of Hypoxia Inducible Factor-1 alpha in human gastric mucosa induced by nonsteroidal anti-inflammatory drugs, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 18, 90-98, 200307
  474. Low body mass index is a risk factor for impaired endothelium-dependent vasodilation in humans: Role of nitric oxide and oxidative stress, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 42(2), 256-263, 20030716
  475. Food deprivation enhances somatostatin and somatostatin receptor subtype expression in rat colon, REGULATORY PEPTIDES, 114(2-3), 167-173, 20030715
  476. Intestinal tuberculosis with hoarseness as a chief complaint due to mediastinal lymphadenitis, Case Rep Gastroenterol, 5(3), 540-545, 20110901
  477. Prevention of hepatitis B virus reactivation in immunosuppressive therapy or chemotherapy., Clin Exp Nephrol., 20110601
  478. Portal-systemic shunt between the inferior mesenteric vein and inferior vena cava in a patient with hepatic encephalopathy: successful occlusion by balloon-occluded retrograde transvenous obliteration., Hiroshima J Med Sci, 60(1), 15-19, 20110501
  479. ★, Will There Be an HCV Meeting in 2020? Summary of the 17th International Meeting on Hepatitis C Virus and Related Viruses., Gastroenterolog, 20110501
  480. Possibility of adoptive immunotherapy with peripheral blood-derived CD3⁻CD56+ and CD3+CD56+ cells for inducing antihepatocellular carcinoma and antihepatitis C virus activity., J Immunother, 34(2), 129-138, 20110301
  481. Current Status of Narrow-Band Imaging Magnifying Colonoscopy for Colorectal Neoplasia in Japan, DIGESTION, 83(3), 167-172, 2011
  482. Splenectomy in Chronic Hepatic Disorders: Portal Vein Thrombosis and Improvement of Liver Function, DIGESTIVE SURGERY, 28(1), 9-14, 2011
  483. Pilot Study of Systemic Combination Therapy with S-1, an Oral Fluoropyrimidine, and Cisplatin for Hepatocellular Carcinoma with Extrahepatic Metastases, HEPATO-GASTROENTEROLOGY, 57(102-03), 1272-1278, 2010
  484. Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants, VIROLOGY, 405(2), 361-369, 20100930
  485. A multicenter, open-label, dose-ranging study to exploratively evaluate the efficacy, safety, and dose-response of tolvaptan in patients with decompensated liver cirrhosis, JOURNAL OF GASTROENTEROLOGY, 45(9), 979-987, 201009
  486. Characterization of colorectal tumors using narrow-band imaging magnification: combined diagnosis with both pit pattern and microvessel features, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 45(9), 1084-1092, 201009
  487. Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients, JOURNAL OF HEPATOLOGY, 53(3), 439-443, 201009
  488. Evaluation of long-term entecavir treatment in stable chronic hepatitis B patients switched from lamivudine therapy, HEPATOLOGY INTERNATIONAL, 4(3), 594-600, 201009
  489. Expression of platelet-derived growth factor (PDGF)-B and PDGF-receptor beta is associated with lymphatic metastasis in human gastric carcinoma, CANCER SCIENCE, 101(9), 1984-1989, 201009
  490. Is Structural Remodeling of Fibrillated Atria the Consequence of Tissue Hypoxia?, CIRCULATION JOURNAL, 74(9), 1815-1821, 201009
  491. ITPA Polymorphism Affects Ribavirin-Induced Anemia and Outcomes of Therapy-A Genome-Wide Study of Japanese HCV Virus Patients, GASTROENTEROLOGY, 139(4), 1190-1197, 201010
  492. Potential role for vascular endothelial growth factor-D as an autocrine factor for human gastric carcinoma cells, CANCER SCIENCE, 101(10), 2121-2127, 201010
  493. ★, Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations, NATURE GENETICS, 42(10), 893-896, 201010
  494. Clinical Impact of Tumor Invasion Depth Staging of Esophageal Squamous Cell Carcinoma Using Endoscopic Ultrasonography, HEPATO-GASTROENTEROLOGY, 58(104), 1423-1429, 2010
  495. Evaluation of portosystemic collaterals by MDCT-MPR imaging for management of hemorrhagic esophageal varices, EUROPEAN JOURNAL OF RADIOLOGY, 76(2), 239-245, 201011
  496. Outcome of endoscopic submucosal dissection for colorectal tumors accompanied by fibrosis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 45(11), 1329-1337, 201011
  497. Quantitative analysis and development of a computer-aided system for identification of regular pit patterns of colorectal lesions, GASTROINTESTINAL ENDOSCOPY, 72(5), 1047-1051, 201011
  498. Transcatheter chemoembolization for unresectable hepatocellular carcinoma and comparison of five staging systems, HEPATOLOGY RESEARCH, 40(11), 1082-1091, 201011
  499. Mesenchymal stem cells enhance growth and metastasis of colon cancer, INTERNATIONAL JOURNAL OF CANCER, 127(10), 2323-2333, 20101115
  500. IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones, VIROLOGY, 407(1), 80-90, 20101110
  501. G to A hypermutation of TT virus, VIRUS RESEARCH, 149(2), 211-216, 201005
  502. A spontaneous Type 1 electrocardiogram pattern in lead V-2 is an independent predictor of ventricular fibrillation in Brugada syndrome, EUROPACE, 12(3), 410-416, 201003
  503. Percutaneous radiofrequency ablation as first-line treatment for small hepatocellular carcinoma: Results and prognostic factors on long-term follow up, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25(3), 597-604, 201003
  504. Intra-arterial 5-fluorouracil/interferon combination therapy for hepatocellular carcinoma with portal vein tumor thrombosis and extrahepatic metastases, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25(6), 1117-1122, 201006
  505. Long-term use of entecavir in nucleoside-naive Japanese patients with chronic hepatitis B infection, JOURNAL OF HEPATOLOGY, 52(6), 791-799, 201006
  506. Pioglitazone improves endothelium-dependent vasodilation in hypertensive patients with impaired glucose tolerance in part through a decrease in oxidative stress, ATHEROSCLEROSIS, 210(2), 521-524, 201006
  507. Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH, JOURNAL OF GASTROENTEROLOGY, 45(7), 750-757, 201007
  508. Establishment of functional telomerase immortalized human hepatocytes and a hepatic stellate cell line for telomere-targeting anticancer drug development, CANCER SCIENCE, 101(7), 1678-1685, 201007
  509. HBx protein is indispensable for development of viraemia in human hepatocyte chimeric mice, JOURNAL OF GENERAL VIROLOGY, 91, 1854-1864, 201007
  510. Practical evaluation of a mouse with chimeric human liver model for hepatitis C virus infection using an NS3-4A protease inhibitor, JOURNAL OF GENERAL VIROLOGY, 91, 1668-1677, 201007
  511. Regular surveillance by imaging for early detection and better prognosis of hepatocellular carcinoma in patients infected with hepatitis C virus, JOURNAL OF GASTROENTEROLOGY, 45(1), 105-112, 201001
  512. Sarpogrelate Hydrochloride, a Selective 5-hydroxytryptamine(2A) Antagonist, Augments Autologous Bone Marrow Mononuclear Cell Implantation-induced Improvement in Endothelium-dependent Vasodilation in Patients With Critical Limb Ischemia, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 55(1), 56-61, 201001
  513. Endothelial function in subjects with isolated low HDL cholesterol: role of nitric oxide and circulating progenitor cells, AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 298(2), E202-E209, 201002
  514. Impaired myocardial blood flow reserve in subjects with metabolic syndrome analyzed using positron emission tomography and N-13 labeled ammonia, EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 37(2), 368-376, 201002
  515. Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease, BMC MEDICAL GENETICS, 11, 20101222
  516. Accumulation of refractory factors for pegylated interferon plus ribavirin therapy in older female patients with chronic hepatitis C, HEPATOLOGY RESEARCH, 40(12), 1155-1167, 201012
  517. Helicobacter pylori dupA and gastric acid secretion are negatively associated with gastric cancer development, JOURNAL OF MEDICAL MICROBIOLOGY, 59(12), 1484-1489, 201012
  518. Predicting the absence of lymph node metastasis of submucosal invasive gastric cancer: Expansion of the criteria for curative endoscopic resection, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 45(12), 1480-1487, 201012
  519. Prolongation of interferon therapy for recurrent hepatitis C after living donor liver transplantation: Analysis of predictive factors of sustained virological response, including amino acid sequence of the core and NS5A regions of hepatitis C virus, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 45(12), 1488-1496, 201012
  520. Zoledronic acid delays disease progression of bone metastases from hepatocellular carcinoma, HEPATOLOGY RESEARCH, 40(12), 1195-1203, 201012
  521. Amino Acid Substitution in Hepatitis C Virus Core Region and Genetic Variation Near the Interleukin 28B Gene Predict Viral Response to Telaprevir with Peginterferon and Ribavirin, HEPATOLOGY, 52(2), 421-429, 201008
  522. Classification of Corkscrew Collaterals in Thromboangiitis Obliterans (Buerger's Disease) - Relationship Between Corkscrew Type and Prevalence of Ischemic Ulcers, CIRCULATION JOURNAL, 74(8), 1684-1688, 201008
  523. Hypersensitivity Reactions to Transcatheter Chemoembolization with Cisplatin and Lipiodol Suspension for Unresectable Hepatocellular Carcinoma, JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 21(8), 1219-1225, 201008
  524. Importance of Serum Concentration of Adefovir for Lamivudine-Adefovir Combination Therapy in Patients with Lamivudine-Resistant Chronic Hepatitis B, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 54(8), 3205-3211, 201008
  525. Elimination of Hepatitis C Virus by Short Term NS3-4A and NS5B Inhibitor Combination Therapy in Human Hepatocyte Chimeric Mice., J Hepatol., 20101001
  526. Efficacy of ecabet sodium enema on intractable rectal ulcer after piecemeal endoscopic mucosal resection for rectal tumor, Clin J Gastroenterol, 3(6), 285-288, 20100901
  527. ★, Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations, Nat Genet, 42(10), 893-6, 20100901
  528. Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin., Hepatology, 52(2), 421-429, 20100801
  529. Impaired coronary microvascular endothelial function in men with metabolic syndrome., World J Cardiol, 26(7), 205-210, 20100701
  530. Non-polypoid colorectal neoplasms in ulcerative colitis, Gastrointest Endosc, 20(3), 525-542, 20100701
  531. Characteristics of esophageal squamous cell carcinomas and lugol-voiding lesions in patients with head and neck squamous cell carcinoma, J Clin Gastroenterol, 44(2), e27-33, 20100201
  532. A Water-soluble extract from culture medium of ganoderma lucidum mycelia suppresses the development of colorectal adenoma, Hiroshima J Med Sci, 59(1), 1--6, 20100101
  533. Amino acid substitutions in core and NS5A regions of the HCV genome can predict virological decrease with pegylated interferon plus ribavirin therapy, ANTIVIRAL THERAPY, 15(8), 1087-1097, 2010
  534. Differential effects of interferon and lamivudine on serum HBV RNA inhibition in patients with chronic hepatitis B, ANTIVIRAL THERAPY, 15(2), 177-184, 2010
  535. Natural Course of Lugol-Voiding Lesions in Patients with Superficial Esophageal Squamous Cell Carcinoma, DIGESTION, 82(1), 60-65, 2010
  536. Relationship between Helicobacter pylori Tyrosine-Phosphorylated CagA-Related Markers and the Development of Diffuse-Type Gastric Cancers: A Case-Control Study, DIGESTION, 82(1), 10-17, 2010
  537. Synchronous and Subsequent Lesions of Serrated Adenomas and Tubular Adenomas of the Colorectum, PATHOBIOLOGY, 77(5), 273-277, 2010
  538. Antiviral activity, dose-response relationship, and safety of entecavir following 24-week oral dosing in nucleoside-naive Japanese adult patients with chronic hepatitis B: a randomized, double-blind, phase II clinical trial, HEPATOLOGY INTERNATIONAL, 3(3), 445-452, 200909
  539. Predictive values of amino acid sequences of the core and NS5A regions in antiviral therapy for hepatitis C: a Japanese multi-center study, JOURNAL OF GASTROENTEROLOGY, 44(9), 952-963, 200909
  540. Ecabet sodium induces neuronal nitric oxide synthase-derived nitric oxide synthesis and gastric adaptive relaxation in the human stomach, JOURNAL OF GASTROENTEROLOGY, 44(11), 1118-1124, 200911
  541. Little Necessity of Acid Inhibition against Proton Pump Inhibitor Rebound Effects and Prior Helicobacter pylori Eradication Therapy in Gastric Ulcer Patients: A Randomized Prospective Study, HEPATO-GASTROENTEROLOGY, 56(91-92), 624-628, 2009
  542. ★, A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians, NATURE GENETICS, 41(5), 591-595, 200905
  543. A Polymorphism in MAPKAPK3 Affects Response to Interferon Therapy for Chronic Hepatitis C, GASTROENTEROLOGY, 136(5), 1796-1805, 200905
  544. Clinical prevention of gastric cancer by Helicobacter pylori eradication therapy: a systematic review, JOURNAL OF GASTROENTEROLOGY, 44(5), 365-371, 200905
  545. Evaluation and validation of computed virtual chromoendoscopy in early gastric cancer, GASTROINTESTINAL ENDOSCOPY, 69(6), 1052-1058, 200905
  546. Intra-arterial 5-fluorouracil/interferon combination therapy for advanced hepatocellular carcinoma with or without three-dimensional conformal radiotherapy for portal vein tumor thrombosis, JOURNAL OF GASTROENTEROLOGY, 44(5), 492-502, 200905
  547. Pathogenetic role of the tyrosine-phosphorylated CagA EPIYA sequence of Helicobacter pylori in histological gastritis in Japanese patients, JOURNAL OF GASTROENTEROLOGY, 44(5), 405-411, 200905
  548. Dose comparison study of pegylated interferon-alpha-2b plus ribavirin in naive Japanese patients with hepatitis C virus genotype 2: A randomized clinical trial, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24(3), 366-371, 200903
  549. Narrow-band imaging magnification predicts the histology and invasion depth of colorectal tumors, GASTROINTESTINAL ENDOSCOPY, 69(3), 631-636, 200903
  550. The first Japanese case of COACH syndrome, HEPATOLOGY RESEARCH, 39(3), 318-323, 200903
  551. Antibodies to Helicobacter pylori and CagA protein are associated with the response to antibacterial therapy in patients with H-pylori-positive API2-MALT1-negative gastric MALT lymphoma, CANCER SCIENCE, 100(6), 1075-1081, 200906
  552. Deletion of angiotensin II type I receptor reduces hepatic steatosis, JOURNAL OF HEPATOLOGY, 50(6), 1226-1235, 200906
  553. Nifedipine Interferes with Migration of Vascular Smooth Muscle Cells via Inhibition of Pyk2-Src Axis, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 16(3), 230-238, 200906
  554. Predicting the response to 48-week combination therapy with peginterferon alpha-2b plus ribavirin from the estimated HCV RNA load index after negative serum change in genotype 1b hepatitis C patients, HEPATOLOGY RESEARCH, 39(6), 531-538, 200906
  555. G-to-A Hypermutation in Hepatitis B Virus (HBV) and Clinical Course of Patients with Chronic HBV Infection, JOURNAL OF INFECTIOUS DISEASES, 199(11), 1599-1607, 200906
  556. Chronic hepatitis C in patients co-infected with human immunodeficiency virus in Japan: a retrospective multicenter analysis, HEPATOLOGY RESEARCH, 39(7), 657-663, 200907
  557. KNACK AND PRACTICAL TECHNIQUE OF COLONOSCOPIC TREATMENT FOCUSED ON ENDOSCOPIC MUCOSAL RESECTION USING SNARE, DIGESTIVE ENDOSCOPY, 21, S38-S42, 200907
  558. Predicting the clinical response to cytapheresis in steroid-refractory or -dependent ulcerative colitis using contrast-enhanced ultrasonography, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 44(7), 831-837, 200907
  559. THERAPEUTIC STRATEGY FOR COLORECTAL LATERALLY SPREADING TUMOR, DIGESTIVE ENDOSCOPY, 21, S43-S46, 200907
  560. Transarterial Infusion Chemotherapy Using Cisplatin-Lipiodol Suspension With or Without Embolization for Unresectable Hepatocellular Carcinoma, CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 32(4), 687-694, 200907
  561. Evaluation of Patients with Esophageal Varices After Endoscopic Injection Sclerotherapy Using Multiplanar Reconstruction MDCT Images, AMERICAN JOURNAL OF ROENTGENOLOGY, 192(1), 122-130, 200901
  562. Significant Correlation Between Spleen Volume and Thrombocytopenia in Liver Transplant Patients: A Concept for Predicting Persistent Thrombocytopenia, LIVER TRANSPLANTATION, 15(2), 208-215, 200902
  563. Amphipathic DNA Polymers Inhibit Hepatitis C Virus Infection by Blocking Viral Entry, GASTROENTEROLOGY, 137(2), 673-681, 200908
  564. Meta-analysis used to identify factors associated with the effectiveness of proton pump inhibitors against non-erosive reflux disease, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24(8), 1326-1332, 200908
  565. Successful hepatitis B vaccination in liver transplant recipients with donor-specific hyporesponsiveness, TRANSPLANT INTERNATIONAL, 22(8), 805-813, 200908
  566. Cigarette Smoking Abolishes Ischemic Preconditioning-Induced Augmentation of Endothelium-Dependent Vasodilation, HYPERTENSION, 53(4), 674-U151, 200904
  567. Comparison of detectability of small-bowel lesions between capsule endoscopy and double-balloon endoscopy for patients with suspected small-bowel disease, GASTROINTESTINAL ENDOSCOPY, 69(4), 857-865, 200904
  568. Effectiveness of prokinetic agents against diseases external to the gastrointestinal tract, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24(4), 537-546, 200904
  569. Metachronous multiple esophageal squamous cell carcinomas and Lugol-voiding lesions after endoscopic mucosal resection, ENDOSCOPY, 41(4), 304-309, 200904
  570. Randomized Trial of High-Dose Interferon-alpha-2b Combined With Ribavirin in Patients With Chronic Hepatitis C: Correlation Between Amino Acid Substitutions in the Core/NS5A Region and Virological Response to Interferon Therapy, JOURNAL OF MEDICAL VIROLOGY, 81(4), 640-649, 200904
  571. Successful treatment of pulmonary metastases associated with advanced hepatocellular carcinoma by systemic 5-fluorouracil combined with interferon-alpha in a hemodialysis patient, HEPATOLOGY RESEARCH, 39(4), 415-420, 200904
  572. Usefulness of Endoscopic Ultrasonography in Determining the Depth of Invasion and Indication for Endoscopic Treatment of Early Gastric Cancer, JOURNAL OF CLINICAL GASTROENTEROLOGY, 43(4), 318-322, 200904
  573. Infliximab treatment for Crohn's disease in a patient with IgA nephropathy, Clin J Gastroenterol, 2, 380-383, 20091201
  574. Cheilitis granulomatosa as an early manifestation of Crohn's disease, Clin J Gastroenterol, 2, 190-193, 20091001
  575. Predicting the clinical response to cytapheresis in steroid-refractory or -dependent ulcerative colitis using contrast-enhanced ultrasonography, Scand J Gastroenterol, 44(5), 405-411, 20090501
  576. Trend in Japanese malpractice litigation involving gastrointestinal endoscopy, Am J Gastroenterol, 104(1), 251-252, 20090101
  577. Usefulness and limitations of transabdominal ultrasonography for detecting small-bowel tumors, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 44(3), 332-338, 2009
  578. Optical biopsy of early gastroesophageal cancer by catheter-based reflectance-type laser-scanning confocal microscopy, JOURNAL OF BIOMEDICAL OPTICS, 13(5), 2008
  579. Prophylaxis against Recurrence of HBV Hepatitis after Living-donor Liver Transplantation, HEPATO-GASTROENTEROLOGY, 55(86-87), 1746-1749, 2008
  580. Colorectal endoscopic submucosal dissection: present status and future perspective, including its differentiation from endoscopic mucosal resection, JOURNAL OF GASTROENTEROLOGY, 43(9), 641-651, 200809
  581. Establishment of an infectious genotype 1b hepatitis C virus clone in human hepatocyte chimeric mice, JOURNAL OF GENERAL VIROLOGY, 89, 2108-2113, 200809
  582. Strategy for treatment of nonerosive reflux disease in Asia, WORLD JOURNAL OF GASTROENTEROLOGY, 14(20), 3123-3128, 20080528
  583. Angiotensin II-Induced osteopontin expression in vascular smooth muscle cells involves G(q/11), Ras, ERK, Src and Ets-1, HYPERTENSION RESEARCH, 31(5), 987-998, 200805
  584. Genetic polymorphisms and head and neck cancer risk (Review), INTERNATIONAL JOURNAL OF ONCOLOGY, 32(5), 945-973, 200805
  585. Long-term ultrasonographic follow-up study of gastric motility in patients with functional dyspepsia, JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 42(2), 144-149, 200803
  586. Role of the angiotensin II type 2 receptor in arterial remodeling after wire injury in mice, HYPERTENSION RESEARCH, 31(6), 1241-1249, 200806
  587. Clinicopathological features of elderly patients with hepatitis C virus-related hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY, 43(7), 550-557, 200807
  588. Coronary vasospasm produces reversible perfusion defects observed during adenosine triphosphate stress myocardial single-photon emission computed tomography, CLINICAL CARDIOLOGY, 31(7), 310-316, 200807
  589. Cytoprotective effect of tauroursodeoxycholate on hepatocyte apoptosis induced by peroxisome proliferator-activated receptor gamma ligand, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23(7), E198-E206, 200807
  590. Evaluation of gastric cancer risk using topography of histological gastritis: A large-scaled cross-sectional study, DIGESTIVE DISEASES AND SCIENCES, 53(7), 1818-1823, 200807
  591. Relationship between Augmentation Index and Flow-Mediated Vasodilation in the Brachial Artery, HYPERTENSION RESEARCH, 31(7), 1293-1298, 200807
  592. Clinical significance of type V-I pit pattern subclassification in determining the depth of invasion of colorectal neoplasms, WORLD JOURNAL OF GASTROENTEROLOGY, 14(2), 211-217, 20080114
  593. Susceptibility of chimeric mice with livers repopulated by serially subcultured human hepatocytes to hepatitis B virus, HEPATOLOGY, 47(2), 435-446, 200802
  594. Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients, HYPERTENSION, 51(2), 446-453, 20080201
  595. Beneficial effects of living-donor liver transplantation on esophageal varices, JOURNAL OF GASTROENTEROLOGY, 43(12), 982-989, 200812
  596. Efficacy of atorvastatin for the treatment of nonalcoholic steatohepatitis with dyslipidemia, METABOLISM-CLINICAL AND EXPERIMENTAL, 57(12), 1711-1718, 200812
  597. Expression of multidrug resistance-associated protein 2 is involved in chemotherapy resistance in human pancreatic cancer, INTERNATIONAL JOURNAL OF ONCOLOGY, 33(6), 1187-1194, 200812
  598. Etiology and outcome of acute liver failure: Retrospective analysis of 50 patients treated at a single center, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23(8), 1216-1222, 200808
  599. Systemic gemcitabine combined with intra-arterial low-dose cisplatin and 5-fluorouracil for advanced hepatocellular carcinoma: Seven cases, WORLD JOURNAL OF GASTROENTEROLOGY, 14(16), 2602-2608, 20080428
  600. Ablation of the Bach1 gene leads to the suppression of atherosclerosis in Bach1 and apolipoprotein E double knockout mice, HYPERTENSION RESEARCH, 31(4), 783-792, 200804
  601. Prospective study of short-term peginterferon-alpha-2a monotherapy in patients who had a virological response at 2 weeks after initiation of interferon therapy, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23(4), 541-545, 200804
  602. Risk factors for hepatocellular carcinoma in a Japanese population: A nested case-control study, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 17(4), 846-854, 200804
  603. Rapid progression of Epstein -Barr-virus-positive gastric diffuse large B-cell lymphoma during chemoradiotherapy: a case report, Clin J Gastroenterol, 1, 105-109, 20081218
  604. Strategy of endoscopic treatment for colorectal tumor: recent progress and perspective, 353-366, 20080815
  605. Endoscopic ultrasonography with double baloon enteroscopy for small bowel diseases, Techniques in Gastrointestinal Endoscopy, 10(3), 113-118, 20080724
  606. A Case of Fulminant Hepatic Failure Caused by Hepatitis E virus79117, Clinical Journal of gastroenterology, 1, 69-74, 20080603
  607. The number of criminal prosecutions against physicians due to medical negligence is on the rise in Japan, Am J Emerg Med, 26(1), 105-106, 20080117
  608. Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells, JOURNAL OF GASTROENTEROLOGY, 43(4), 298-304, 2008
  609. Combination therapy of oral fluoropyrimidine anticancer drug S-1 and interferon alpha for HCC patients with extrahepatic metastases, ONCOLOGY, 75(1-2), 8-16, 2008
  610. Evaluation of colon cancer vascularity by flash echo imaging, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 43(2), 223-228, 2008
  611. Predictors and long-term prognostic implications of angiographic slow/no-flow during percutaneous coronary intervention for acute myocardial infarction, INTERNAL MEDICINE, 47(10), 899-906, 2008
  612. Relation between histologic gastritis and gastric motility in Japanese patients with functional dyspepsia: evaluation by transabdominal ultrasonography, JOURNAL OF GASTROENTEROLOGY, 43(5), 332-337, 2008
  613. Role of the Gastrin-Gastrin Receptor System in the Expansive Growth of Human Gastric Neoplasms, DIGESTION, 78(2-3), 163-170, 2008
  614. Validating a Markov Model of Treatment for Hepatitis C Virus-related Hepatocellular Carcinoma, METHODS OF INFORMATION IN MEDICINE, 47(6), 529-540, 2008
  615. Pycnogenol (R), French maritime pine bark extract, augments endothelium-dependent vasodilation in humans, HYPERTENSION RESEARCH, 30(9), 775-780, 200709
  616. Serum pepsinogen levels in the Japanese population: Prospective study of 9 years of follow-up, HEPATO-GASTROENTEROLOGY, 54(78), 1887-1890, 200709
  617. Effects of a 24-week course of interferon-a therapy after curative treatment of hepatitis C virus-associated hepatocellular carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(40), 5343-5350, 20071028
  618. Low-dose intermittent interferon-alpha therapy for HCV-related liver cirrhosis after curative treatment of hepatocellular carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(39), 5188-5195, 20071021
  619. Nodular gastritis with Helicobacter pylori infection is strongly associated with diffuse-type gastric cancer in young patients, DIGESTIVE ENDOSCOPY, 19(4), 180-184, 200710
  620. Pretreatment predictor of response, time to progression, and survival to intraarterial 5-fluorouracil/interferon combination therapy in patients with advanced hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY, 42(10), 845-853, 200710
  621. Treatment of functional dyspepsia with serotonin agonists: A meta-analysis of randomized controlled trials, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(10), 1566-1570, 200710
  622. Genetic polymorphisms and esophageal cancer risk, INTERNATIONAL JOURNAL OF CANCER, 121(8), 1643-1658, 20071015
  623. Biliary complications after duct-to-duct biliary reconstruction in living-donor liver transplantation: Causes and treatment, WORLD JOURNAL OF SURGERY, 31(11), 2222-2229, 200711
  624. Evaluation of microvessels in colorectal tumors by narrow band imaging magnification, GASTROINTESTINAL ENDOSCOPY, 66(5), 945-952, 200711
  625. Similar effects of recombinant interferon-alpha-2b and natural interferon-alpha when combined with intra-arterial 5-fluorouracil for the treatment of advanced hepatocellular carcinoma, LIVER INTERNATIONAL, 27(9), 1209-1216, 200711
  626. Measurement of flow-mediated vasodilation of the brachial artery - A comparison of measurements in the seated and supine positions, CIRCULATION JOURNAL, 71(5), 736-740, 200705
  627. Role of Helicobacter pylori infection and chronic inflammation in gastric cancer in the cardia, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 37(5), 365-369, 200705
  628. Serum HBV RNA is a predictor of early emergence of the YMDD mutant in patients treated with lamivudine, HEPATOLOGY, 45(5), 1179-1186, 200705
  629. Earthworm fibrinolytic enzyme: anti-tumor activity on human hepatoma cells in vitro and in vivo, CHINESE MEDICAL JOURNAL, 120(10), 898-904, 20070520
  630. Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon, FEBS LETTERS, 581(10), 1983-1987, 20070515
  631. Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(3), 304-310, 200703
  632. Repetition of ischemic preconditioning augments endothelium-dependent vasodilation in humans - Role of endothelium-derived nitric oxide and endothelial progenitor cells, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 27(6), 1403-1410, 200706
  633. Immunohistochemical molecular markers as predictors of curability of endoscopically resected submucosal colorectal cancer, WORLD JOURNAL OF GASTROENTEROLOGY, 13(28), 3829-3835, 20070728
  634. Elevated levels of serum advanced glycation end products in patients with non-alcoholic steatohepatitis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(7), 1112-1119, 200707
  635. Endoscopic submucosal dissection for colorectal neoplasia: possibility of standardization, GASTROINTESTINAL ENDOSCOPY, 66(1), 100-107, 200707
  636. Optical biopsy of GI lesions by reflectance-type laser-scanning confocal microscopy, GASTROINTESTINAL ENDOSCOPY, 66(1), 144-149, 200707
  637. Techniques and pitfalls of endoscopic submucosal dissection for colorectal tumors, DIGESTIVE ENDOSCOPY, 19, S30-S33, 200707
  638. Clinical features and prognosis of patients with extrahepatic metastases from hepatocellular carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(3), 414-420, 20070121
  639. Basis of decreased risk of gastric cancer in severe atrophic gastritis with eradication of Helicobacter pylori, DIGESTIVE DISEASES AND SCIENCES, 52(1), 232-239, 200701
  640. Gene delivery of paraoxonase-1 inhibits neointimal hyperplasia after arterial balloon-injury in rabbits fed a high-fat diet, HYPERTENSION RESEARCH, 30(1), 85-91, 200701
  641. Lymphatic vessel density at the site of deepest penetration as a predictor of lymph node metastasis in submucosal colorectal cancer, DISEASES OF THE COLON & RECTUM, 50(1), 13-21, 200701
  642. Non-SCN5A related Brugada syndromes: Verification of normal splicing and trafficking of SCN5A without exonic mutations, ANNALS OF HUMAN GENETICS, 71, 8-17, 200701
  643. Cavernous hemangioma in the ascending colon treated by endoscopic mucosal resection, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(2), 280-281, 200702
  644. Dual effect of APOBEC3G on Hepatitis B virus, JOURNAL OF GENERAL VIROLOGY, 88, 432-440, 200702
  645. Immune response to CagA protein is associated with improved platelet count after Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura, HELICOBACTER, 12(1), 36-42, 200702
  646. Roles of Rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 49(6), 698-705, 20070213
  647. Selective decrease in colonic CD56(+) T and CD161(+) T cells in the inflamed mucosa of patients with ulcerative colitis, WORLD JOURNAL OF GASTROENTEROLOGY, 13(45), 5995-6002, 20071207
  648. Single lymphocyte analysis with a microwell array chip, CYTOMETRY PART A, 71A(12), 1003-1010, 200712
  649. Successful treatment of an entecavir-resistant hepatitis B virus variant, JOURNAL OF MEDICAL VIROLOGY, 79(12), 1811-1817, 200712
  650. Involvement of Kruppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(29), 3932-3938, 20070807
  651. Acute moderate-intensity exercise induces vasodilation through oxide bioavailiability an increase in nitric in humans, AMERICAN JOURNAL OF HYPERTENSION, 20(8), 825-830, 200708
  652. Low serum level of hepatitis B indicates unlikely reactivation core-related antigen of hepatitis after cessation of lamivudine therapy, HEPATOLOGY RESEARCH, 37(8), 661-666, 200708
  653. The long-term outcome of patients with bleeding gastric varices after balloon-occluded retrograde transvenous obliteration, JOURNAL OF GASTROENTEROLOGY, 42(8), 663-672, 200708
  654. Host factors contributing to the discovery of gastric cancer after successful eradication therapy of Helicobacter pylori: Preliminary report, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(4), 571-576, 200704
  655. New method of evaluating gastric mucosal blood flow by ultrasound, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 42(4), 513-518, 200704
  656. Pycnogenol, French maritime pine bark extract, augments endothelium-dependent vasodilation in humans., HYPERTENSION RESEARCH, 775-780, 20070901
  657. Predicting the need for surgery in Crohn's disease with contrast harmonic ultrasound, Scand J Gastroenterol, 42, 577-585, 20070601
  658. Should splenectomy be performed for hepatitis C patients undergoing living-donor liver transplantation, J Gastroenterol Hepatol, 22(6), 959-960, 20070601
  659. Helicobacter pylori-associated gastritisis related to babA2expression without heterogeneity of the 3' region of the cagA genotype in Gastric Biopsy Specimens, Pathobiology, 74(5), 1-7, 20070401
  660. The effects of different intensities of acute exercise on systemic hemodynamics and forearm vascular function in humans., AMERICAN JUORNAL OF HYPERTENSION, 825-830, 20070214
  661. Carvedilol improves endothelium-dependent vasodilation in patients with dilated cardiomyopathy., HEART, 247-248, 20070201
  662. Balloon-occluded retrograde transvenous obliteration for portal-systemic encephalopathy due to superior mesenteric-caval shunt via the right gonadal vein, INTERNAL MEDICINE, 46(17), 1479-1480, 2007
  663. Efficacy of percutaneous cementoplasty for bone metastasis from hepatocellular carcinoma, ONCOLOGY, 72(5-6), 285-292, 2007
  664. Eicosapentaenoic acid could permit maintenance of the original ribavirin dose in chronic hepatitis C virus patients during the first 12 weeks of combination therapy with pegylated interferon-alpha and ribavirin, INTERVIROLOGY, 50(6), 439-446, 2007
  665. Helicobacter pylori - Associated gastritis is related to babA2 expression without heterogeneity of the 3 ' region of the cagA genotype in gastric biopsy specimens, PATHOBIOLOGY, 74(5), 309-316, 2007
  666. Predicting the need for surgery in Crohn's disease with contrast harmonic ultrasound, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 42(5), 577-585, 2007
  667. A case of Crohn's disease with hydronephrosis caused by ureteropelvic junction obstruction, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 18(9), 1015-1018, 200609
  668. A ligand for peroxisome proliferator-activated receptor gamma inhibits human cholangiocarcinoma cell growth: Potential molecular targeting strategy for cholangioma, DIGESTIVE DISEASES AND SCIENCES, 51(9), 1650-1657, 200609
  669. Helicobacter pylori infection is the major risk factor for gastric inflammation in the cardia, DIGESTIVE DISEASES AND SCIENCES, 51(9), 1582-1588, 200609
  670. Medical malpractice litigation in gastroenterological practice in Japan: A 22-yr review of civil court cases, AMERICAN JOURNAL OF GASTROENTEROLOGY, 101(9), 1951-1953, 200609
  671. Autologous bone marrow mononuclear cell implantation induces angiogenesis and bone regeneration in a patient with compartment syndrome, CIRCULATION JOURNAL, 70(10), 1362-1364, 200610
  672. Endoscopic submucosal dissection for residual/local recurrence of early gastric cancer after endoscopic mucosal resection, ENDOSCOPY, 38(10), 996-1000, 200610
  673. Genetic progression and divergence in superficial esophageal squamous cell carcinoma by loss of heterozygosity analysis, ONCOLOGY REPORTS, 16(4), 685-691, 200610
  674. High-magnification colonoscopy (with videos), GASTROINTESTINAL ENDOSCOPY, 64(4), 604-613, 200610
  675. Management of intraductal papillary-mucinous neoplasm of the pancreas - Treatment strategy based on morphologic classification, JOURNAL OF CLINICAL GASTROENTEROLOGY, 40(9), 856-862, 200610
  676. Aged garlic extract has potential suppressive effect on colorectal adenomas in humans, JOURNAL OF NUTRITION, 136(3), 821S-826S, 200603
  677. Deletion of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach, INTERNATIONAL JOURNAL OF ONCOLOGY, 28(6), 1361-1367, 200606
  678. Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production, ATHEROSCLEROSIS, 186(2), 390-395, 200606
  679. Measurement of hepatitis B virus core-related antigen is valuable for identifying patients who are at low risk of lamivudine resistance, LIVER INTERNATIONAL, 26(1), 90-96, 200602
  680. Nonpolypoid (flat and depressed) colorectal neoplasms, GASTROENTEROLOGY, 130(2), 566-576, 200602
  681. Suppression of STAT3 activity by duplin, which is a negative regulator of the Wnt signal, JOURNAL OF BIOCHEMISTRY, 139(2), 305-314, 200602
  682. The nicorandil-induced vasodilation in humans is inhibited by miconazole, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 45(4), 290-294, 200504
  683. Expression of p53 protein in esophageal squamous cell carcinoma: relation to hypoxia-inducible factor-1alpha, angiogenesis and apoptosis., Pathobiology, 72, 179-185, 20050901
  684. Ablation of ventricular tachycardia originating from the right ventricle associated with scleroderma cardiomyopathy., J Arrhythmia, 21(5), 542-545, 20050401
  685. Angiotensin II type I receptor blocker and endothelial function in humans: role of nitric oxide and oxidative stress., Curr.Med.Chem, 3(2), 133-148, 20050401
  686. Relationship between histopathological features and type V pit pattern determined by magnifying videocolonoscopy in early colorectal carcinoma, Dig Endos, 17, 117-122, 20050401
  687. Effects of angiotensin II on the expression of MCP-1 in hepatic stellate line LI90, Japanese Pharmaology and Therapeutics, 32, 143-5, 20050201
  688. Molecular evolutionaly analyses implicate injecthion treatment for schistosomiasis in the initial hepatitis C epidemics in japan, Journal of Hepatology, 42, 47-53, 20050101
  689. Superficial type serrated adenoma in ulcerative colitis resected by endoscopic submucosal dissection, Dig Endosc, 17, S49-S52, 20050101
  690. A classification system of echogenicity for gastrointestinal neoplasms, DIGESTION, 72(1), 8-12, 2005
  691. Expression of p53 protein in esophageal squamous cell carcinoma: Relation to hypoxia-inducible factor-1 alpha, angiogenesis and apoptosis, PATHOBIOLOGY, 72(4), 179-185, 2005
  692. Effect of different intensities of exercise on endothelium-dependent vasodilation in humans - Role of endothelium-dependent nitric oxide and oxidative stress, CIRCULATION, 108(5), 530-535, 20030805
  693. Impact of aging on the development of hepatocellular carcinoma in patients with hepatitis C virus infection in Japan, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(8), 894-900, 200308
  694. Vascular endothelial growth factor-C expression predicts lymph node metastasis of human gastric carcinomas invading the submucosa, EUROPEAN JOURNAL OF CANCER, 38(10), 1413-1419, 200207
  695. p53 codon 72 polymorphism in gastric cancer susceptibility in patients with Helicobacter pylori-associated chronic gastritis, INTERNATIONAL JOURNAL OF CANCER, 100(3), 304-308, 20020720
  696. Genotype, slow decrease in virus titer during interferon treatment and high degree of sequence variability of hypervariable region are indicative of poor response to interferon treatment in patients with chronic hepatitis type C, J Hepatol, 23, 648-653, 19950401
  697. Genotyping of hepatitis C virus by the polymerase chain reaction: a comparison of two PCR-based methods using core or NS5 primers, Int Hepatol Commun, 4, 67-71, 19950401
  698. Molecular analysis of intraspousal transmission of hepatitis C virus, J Hepatol, 22, 431-439, 19950401
  699. Novel hepatitis B variants in sibling carriers positive for antibody to hepatitis B surface antigen, Int Hepatol Commun, 4, 121-125, 19950401
  700. Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 346(1), 67-73, 20060721
  701. A case of multiple hepatic peribiliary cysts which contributed to the obstructive jaundice and led to liver failure at the young man with von Recklinghausen's disease, HEPATOLOGY RESEARCH, 35(3), 222-227, 200607
  702. Clinicopathologic and genetic characteristics of gastric cancer in young male and female patients, ONCOLOGY REPORTS, 16(1), 11-15, 200607
  703. Double-balloon enteroscopy in patients with GI bleeding of obscure origin, GASTROINTESTINAL ENDOSCOPY, 64(1), 135-140, 200607
  704. Gastrointestinal stromal tumor in jejunum: Diagnosis using contrast-enhanced ultrasonography and double-balloon enteroscopy, DIGESTIVE DISEASES AND SCIENCES, 51(7), 1236-1240, 200607
  705. Neuropilin-1 is involved in regulation of apoptosis and migration of human colon cancer, INTERNATIONAL JOURNAL OF ONCOLOGY, 29(1), 105-116, 200607
  706. Real-time visualization and quantitation of canine gastric mucosal blood flow by contrast-enhanced ultrasonography, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 41(7), 856-861, 200607
  707. dEvaluation of endoscopic and histological findings in Helicobacter pylori-positive Japanese young adults, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 21(1), 258-261, 200601
  708. Defensive medicine practices among gastroenterologists in Japan, WORLD JOURNAL OF GASTROENTEROLOGY, 12(47), 7671-7675, 20061221
  709. Advantage of endoscopic submucosal dissection compared with EMR for early gastric cancer, GASTROINTESTINAL ENDOSCOPY, 64(6), 877-883, 200612
  710. Feasibility of freeze-dried sera for serological and molecular biological detection of hepatitis B and C viruses, JOURNAL OF CLINICAL MICROBIOLOGY, 44(12), 4593-4595, 200612
  711. Genetic and pathologic characteristics of gastrointestinal stromal tumors in extragastric lesions, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 18(6), 1067-1071, 200612
  712. Small-intestinal Peutz-Jeghers polyps resected by endoscopic polypectomy with double-balloon enteroscopy and removal confirmed by ultrasonography, DIGESTIVE DISEASES AND SCIENCES, 51(12), 2337-2340, 200612
  713. Effects of acute administration of caffeine on vascular function, AMERICAN JOURNAL OF CARDIOLOGY, 98(11), 1538-1541, 20061201
  714. Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 346(3), 658-664, 20060804
  715. Oxidative stress, endothelial function and angiogenesis induced by cell therapy and gene therapy, CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 7(2), 109-116, 200604
  716. The effect of Helicobacter pylori eradication therapy on gastric ulcer healing after endoscopic mucosal resection, JOURNAL OF CLINICAL GASTROENTEROLOGY, 40(4), 293-296, 200604
  717. The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines, INTERNATIONAL JOURNAL OF ONCOLOGY, 28(4), 915-921, 200604
  718. The usefulness of transabdominal ultrasound for the diagnosis of lower gastrointestinal bleeding, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 23(8), 1267-1272, 20060415
  719. High-magnification colonoscopy (with Videos), Gastrointest Endosc, 64(4), 604-613, 20061001
  720. Management of Intraductal Papillary -mucinous Neoplasm of the Pancreas, J Clin Gastroenterol, 40(9), 856-862, 20061001
  721. Suppression of interferon-related promoter activation by hepatitis C virus proteins expressed in cultured cells., Hiroshima Journal of Medical Sciences, 55(3), 71-77, 20060901
  722. Pit pattern diagnosis for colorectal neoplasia using narrow band imaging magnification, Dig Endosc, 18, S52-S56, 20060701
  723. Delection of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach., Int J Oncology, 28, 1361-1367, 20060601
  724. Ablation of indiopathic ventricular tachycardia with a left Bundle-Branch block morphology originating from the pulmonary artery., J Arrthmia, 22(3), 180-186, 20060401
  725. Coronary sinus Morphology in Patients with Posteroseptal Atrioventricular Accessory Pathways., J Arrthmia, 22(3), 149-154, 20060401
  726. Edaravone(3-Methyl-1-Phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases., Recent Patents on Cardiovascular Drug Discovery, 1, 85-93, 20060401
  727. Helicobacter pylori infection is the major risk factor for atrophic gastritis, San Diego, 20060301
  728. Causal role of Helicobacter pylori infection and eradication therapy in gastric carcinogenesis., World J Gastroenterol, 12(1), 10-16, 20060101
  729. Evaluation of endoscopic and histological findings in Helicobacter pylori-positive Japanese young adults, J Gastroenterol Hepatol, 21, 258-261, 20060101
  730. Development of a novel method to detect Helicobacter pylori cagA genotype from paraffin-embedded materials: Comparison between patients with duodenal ulcer and gastric cancer in young Japanese, DIGESTION, 73(1), 47-53, 2006
  731. Evolution of hepatitis C virus quasispecies during ribavirin and interferon-alpha-2b combination therapy and interferon-alpha-2b monotherapy, INTERVIROLOGY, 49(6), 352-361, 2006
  732. Nuclear and mitochondrial DNA microsatellite instability in gastrointestinal stromal tumors, PATHOBIOLOGY, 73(2), 93-97, 2006
  733. Prolonged negative HCV-RNA status led to a good outcome in chronic hepatitis C patients with genotype 1b and super-high viral load, INTERVIROLOGY, 49(6), 362-369, 2006
  734. Successive, rapid recurrences of in-stent restenoses in a woman with angina pectoris, INTERNAL MEDICINE, 45(19), 1093-1096, 2006
  735. Cardiac glands hyperplastic polyp of the stomach, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(9), 1461-1463, 200509
  736. ★, A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5 ' flanking region of SMYD3 is a risk factor for human cancers, NATURE GENETICS, 37(10), 1104-1107, 200510
  737. Adrenomedullin causes coronary vasodilation in humans - Effects of inhibition of nitric oxide synthesis, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 46(4), 534-539, 200510
  738. Diagnostic ability of high-frequency ultrasound probe sonography in staging early gastric cancer, especially for submucosal invasion, ABDOMINAL IMAGING, 30(5), 518-523, 200510
  739. Relationship between endothelial function in the coronary and brachial arteries, CLINICAL CARDIOLOGY, 28(10), 460-466, 200510
  740. Therapeutic effect of repeated natural killer T cell stimulation in mouse cholangitis complicated by colitis, DIGESTIVE DISEASES AND SCIENCES, 50(10), 1844-1851, 200510
  741. Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus, HEPATOLOGY, 42(5), 1046-1054, 200511
  742. Reliable and cost-effective screening of inherited heterozygosity by Zn2+-cyclen polyacrylamide gel electrophoresis, CLINICAL CHEMISTRY, 51(11), 2195-2198, 200511
  743. Somatic mutations of mitochondrial DNA in digestive tract cancers, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(11), 1679-1684, 200511
  744. Monocyte chemoattractant protein-1 transfection induces angiogenesis and tumorigenesis of gastric carcinoma in nude mice via macrophage recruitment, CLINICAL CANCER RESEARCH, 11(21), 7629-7636, 20051101
  745. Role of the JNK pathway in thrombin-induced ICAM-1 expression in endothelial cells, CARDIOVASCULAR RESEARCH, 68(2), 289-298, 20051101
  746. Angiotensin II participates in hepatic inflammation and fibrosis through MCP-1 expression, DIGESTIVE DISEASES AND SCIENCES, 50(5), 942-948, 200505
  747. Clinical features of gastric cancer discovered after successful eradication of Helicobacter pylori: results from a 9-year prospective follow-up study in Japan, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21(9), 1121-1126, 20050501
  748. Involvement of proinflammatory cytokines IL-1 beta and IL-6 in progression of human gastric carcinoma, ANTICANCER RESEARCH, 25(2A), 709-713, 2005
  749. A nuclear receptor ligand down-regulates cytosolic phospholipase A(2) expression to reduce bile acid-induced cyclooxygenase 2 activity in cholangiocytes: Implications of anticarcinogenic action of farnesoid X receptor agonists, DIGESTIVE DISEASES AND SCIENCES, 50(3), 514-524, 200503
  750. G to A hypermutation of hepatitis B virus, HEPATOLOGY, 41(3), 626-633, 200503
  751. Ubquitin-interacting motifs of epsin are involved in the regulation of insulin-dependent endocytosis, JOURNAL OF BIOCHEMISTRY, 137(3), 355-364, 200503
  752. Morphological changes in human gastric tumours after eradication therapy of Helicobacter pylori in a short-term follow-up, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21(5), 559-566, 20050301
  753. Effect of famotidine on recurrent bleeding after successful endoscopic treatment of bleeding peptic ulcer, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21, 73-78, 200506
  754. Effect of long-term half-dose famotidine therapy on corpus gastritis in peptic ulcer disease, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21, 99-104, 200506
  755. Quantitative analysis of lymphangiogenic markers for predicting metastasis of human gastric carcinoma to lymph nodes, INTERNATIONAL JOURNAL OF CANCER, 115(3), 388-392, 20050620
  756. Hepatitis C virus core protein modulates fatty acid metabolism and thereby causes lipid accumulation in the liver, DIGESTIVE DISEASES AND SCIENCES, 50(7), 1361-1371, 200507
  757. A case of congenital absence of the portal vein, HEPATOLOGY RESEARCH, 31(1), 43-47, 200501
  758. A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer, JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 131(1), 19-25, 200501
  759. Eradication of Helicobacter pylori increases the incidence of hyperlipidaemia and obesity in peptic ulcer patients, DIGESTIVE AND LIVER DISEASE, 37(1), 39-43, 200501
  760. Infliximab therapy for Crohn's disease in a patient with chronic hepatitis B, DIGESTIVE DISEASES AND SCIENCES, 50(1), 163-166, 200501
  761. Molecular evolutionary analyses implicate injection treatment for schistosomiasis in the initial hepatitis C epidemics in Japan, JOURNAL OF HEPATOLOGY, 42(1), 47-53, 200501
  762. Single dose of OCH improves mucosal T helper type 1/T helper type 2 cytokine balance and prevents experimental colitis in the presence of v alpha 14 natural killer T cells in mice, INFLAMMATORY BOWEL DISEASES, 11(1), 35-41, 200501
  763. Suppression of macrophage infiltration inhibits activation of hepatic stellate cells and liver fibrogenesis in rats, GASTROENTEROLOGY, 128(1), 138-146, 200501
  764. Vascular function in patients with lower extremity peripheral arterial disease: a comparison of functions in upper and lower extremities, ATHEROSCLEROSIS, 178(1), 179-185, 200501
  765. Biphasic effect of HMG-CoA reductase inhibitor, pitavastatin, on vascular endothelial cells and angiogenesis, CIRCULATION JOURNAL, 69(12), 1547-1555, 200512
  766. Smoking, endothelial function, and Rho-kinase in humans, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 25(12), 2630-2635, 200512
  767. Glycochenodeoxycholate plays a carcinogenic role in immortalized mouse cholanglocytes via oxidative DNA damage, FREE RADICAL BIOLOGY AND MEDICINE, 39(11), 1418-1427, 20051201
  768. Expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in early gastric carcinoma: correlation with clinicopathological parameters, CANCER LETTERS, 226(1), 85-90, 20050808
  769. A nuclear receptor-mediated choleretic action of fibrates is associated with enhanced canalicular membrane fluidity and transporter activity mediating bile acid-independent bile secretion, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 12(4), 211-217, 20050825
  770. A combination of the Helicobacter pylori stool antigen test and urea breath test is useful for clinical evaluation of eradication therapy: A multicenter study, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(8), 1241-1245, 200508
  771. Multiple carcinoid tumors of the ileum preoperatively diagnosed by enteroscopy with the double-balloon technique, GASTROINTESTINAL ENDOSCOPY, 62(2), 315-318, 200508
  772. Loss of heterozygosity on chromosome 10p14-p15 in colorectal carcinoma, PATHOBIOLOGY, 72(4), 220-224, 2005
  773. Improvement of atrial signal-averaged electrocardiographic abnormalities after radiofrequency catheter ablation in persistent atrial flutter, JAPANESE HEART JOURNAL, 45(5), 761-770, 200409
  774. Concise prediction models of anticancer efficacy of 8 drugs using expression data from 12 selected genes, INTERNATIONAL JOURNAL OF CANCER, 111(4), 617-626, 20040910
  775. Partial characterization of cytoprotective mechanisms of lecithin against bile salt-induced bile duct damage, JOURNAL OF GASTROENTEROLOGY, 39(10), 955-960, 200410
  776. Effect of edaravone, a novel free radical scavenger, on endothelium-dependent vasodilation in smokers, AMERICAN JOURNAL OF CARDIOLOGY, 94(8), 1070-1073, 20041015
  777. Apolipoprotein E phenotype affects the malondialdehyde-modified LDL concentration and forearm endothelial function in postmenopausal women, CLINICAL ENDOCRINOLOGY, 61(5), 619-625, 200411
  778. Magnifying colonoscopic features of ulcerative colitis reflect histologic inflammation, INFLAMMATORY BOWEL DISEASES, 10(6), 737-744, 200411
  779. A case of latent primary biliary cirrhosis, HEPATOLOGY RESEARCH, 28(3), 166-169, 200403
  780. Atrial contraction after surgical isolation of the left atrial posterior wall concomitant with mitral valve replacement, CIRCULATION JOURNAL, 68(3), 204-207, 200403
  781. Clinical significance of angiopoietin-2 expression at the deepest invasive tumor site of advanced colorectal carcinoma, INTERNATIONAL JOURNAL OF ONCOLOGY, 24(3), 539-547, 200403
  782. Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia, CIRCULATION, 109(10), 1215-1218, 20040316
  783. Fas and Fas ligand: Expression and soluble circulating levels in bile duct carcinoma, ONCOLOGY REPORTS, 11(6), 1183-1186, 200406
  784. Initial experience with catheter probe US when using a multibending endoscope, GASTROINTESTINAL ENDOSCOPY, 59(7), 889-894, 200406
  785. Induction of apoptosis by ionizing radiation and CI-1033 in HuCCT-1 cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 319(1), 114-119, 20040618
  786. Chronic gastritis with expression of inducible nitric oxide synthase is associated with high expression of interleukin-6 and hypergastrinaemia, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 19(12), 1309-1314, 20040615
  787. Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma, INTERNATIONAL JOURNAL OF CANCER, 110(2), 212-218, 20040610
  788. Chromosomal and microsatellite instability in sporadic gastric cancer, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 19(7), 756-760, 200407
  789. Regulation of vascular endothelial growth factor (VEGF)-C and VEGF-D expression by the organ microenvironment in human colon carcinoma, EUROPEAN JOURNAL OF CANCER, 40(10), 1604-1609, 200407
  790. Relation between C reactive protein concentrations and coronary microvascular endothelial function, HEART, 90(7), 750-754, 200407
  791. Expression of human telomerase reverse transcriptase mRNA in esophageal cancers and precancerous lesions, ONCOLOGY REPORTS, 11(1), 51-55, 200401
  792. Expression of VEGF-C and VEGF-D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma, CANCER SCIENCE, 95(1), 32-39, 200401
  793. Gemcitabine suppresses malignant ascites of human pancreatic cancer: Correlation with VEGF expression in ascites, ONCOLOGY REPORTS, 11(1), 73-80, 200401
  794. Angiogenic switch occurs during the precancerous stage of human esophageal squamous cell carcinoma, ONCOLOGY REPORTS, 11(2), 315-319, 200402
  795. Clinicopathologic and endoscopic features of colorectal serrated adenoma: differences between polypoid and superficial types, GASTROINTESTINAL ENDOSCOPY, 59(2), 213-219, 200402
  796. Mutation of the von Hippel-Lindau (VHL) gene in human colorectal carcinoma: Association with cytoplasmic accumulation of hypoxia-inducible factor (HIF)-1 alpha, CANCER SCIENCE, 95(2), 149-153, 200402
  797. Epigenetic inactivation of SOCS-1 by CpG island hypermethylation in human gastric carcinoma, INTERNATIONAL JOURNAL OF CANCER, 112(6), 1003-1009, 20041220
  798. Expression of hypoxia-inducible factor (HIF)-1 alpha is associated with vascular endothelial growth factor expression and tumour anglogenesis in human oesophageal squamous cell carcinoma, EUROPEAN JOURNAL OF CANCER, 40(12), 1904-1912, 200408
  799. Frequent loss of heterozygosity on chromosome 10p14-p15 in esophageal dysplasia and squamous cell carcinoma, ONCOLOGY REPORTS, 12(2), 333-337, 200408
  800. Immune response in mouse experimental cholangitis associated with colitis induced by dextran sulfate sodium, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 19(8), 910-915, 200408
  801. Identification of rare polymerase variants of hepatitis B virus using a two-stage PCR with peptide nucleic acid clamping, JOURNAL OF MEDICAL VIROLOGY, 72(4), 558-565, 200404
  802. Magnifying gastroendoscopy for diagnosis of histologic gastritis in the gastric antrum, DIGESTIVE AND LIVER DISEASE, 36(4), 286-291, 200404
  803. Sonographic detection of longitudinal ulcers in Crohn disease, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 39(4), 322-326, 200404
  804. Expression of hypoxia-inducible factor (HIF)-1alpha is associated with vascular endothelial growth factor expression and tumour angiogenesis in human oesophageal squamous cell carcinoma., Eur J Cancer, 40, 1904-1912, 20040801
  805. Relationship between C-reactive protein concetrations and coronary microvascular endothelial function0, Heart, 90, 750-754, 20040701
  806. Effects of aged garlic extract (AGE) on colorectal adenomas: a double-blinded study, Hiroshima J Med Sci, 53(3--4), 39-45, 20040401
  807. Pathophysiology of nonalcoholic steatohepatitis (NASH)-Relation to adipocytokine and advanced glycation end products., Japanese Pharmaology & Therapeutics, 32, 107-9, 20040201
  808. Clinical usefulness of high-frequency ultrasound probes for new invasion depth diagnosis in submucosal colorectal carcinoma, Dig Endosc, 16, S49-S52, 20040101
  809. Characteristics and trends of clarithromycin-resistant Helicobacter pylori isolates in Japan over a decade, PATHOBIOLOGY, 71(3), 159-163, 2004
  810. Frequent loss of RUNX3 expression by promoter hypermethylation in gastric carcinoma, PATHOBIOLOGY, 71(3), 137-143, 2004
  811. Mucin phenotype and background mucosa of intramucosal differentiated-type adenocarcinoma of the stomach, ONCOLOGY, 66(5), 379-387, 2004
  812. Frequent loss of heterozygosity on chromosome 10p15, a putative telomerase repressor/senescence gene locus, in gastric cancer, ONCOLOGY REPORTS, 10(5), 1297-1299, 2003
  813. Prognostic value of p53 and Ki-67 expression in resected or biopsy specimens of bile duct carcinoma, ONCOLOGY REPORTS, 10(5), 1091-1096, 2003
  814. Does intragastric nitrite concentration reflect gastric carcinogenesis in Japanese Helicobacter pylori-infected patients?, DIGESTIVE DISEASES AND SCIENCES, 48(9), 1730-1736, 200309
  815. Gastric juice nitrite and vitamin C in patients with gastric cancer and atrophic gastritis: is low acidity solely responsible for cancer risk?, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 15(9), 987-993, 200309
  816. Necessity of multiple gastric biopsies from different sites for detection of clarithromycin-resistant Helicobacter pylori strains, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(9), 942-946, 200309
  817. p53 expression, K-ras gene mutation and microsatellite instability in gastric B-cell lymphomas, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 18(9), 1047-1053, 200309
  818. Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 12(4), 437-442, 200310
  819. Clinical significance of thrombospondin-1 expression in relation to vascular endothelial growth factor and interleukin-10 expression at the deepest invasive tumor site of advanced colorectal carcinoma, INTERNATIONAL JOURNAL OF ONCOLOGY, 23(4), 901-911, 200310
  820. Disruption of the type 2 dopamine receptor gene causes a sodium-dependent increase in blood pressure in mice, AMERICAN JOURNAL OF HYPERTENSION, 16(10), 853-858, 200310
  821. Prevalence of Helicobacter pylori resistance to clarithromycin and metronidazole determined by 23S ribosomal RNA and rdxA gene analyses in Hiroshima, Japan, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 18(10), 1202-1207, 200310
  822. The promoter methylation status of the DNA repair gene O-6-methylguanine-DNA methyltransferase in ulcerative colitis, VIRCHOWS ARCHIV, 443(4), 518-523, 200310
  823. Clinicopathologic features and endoscopic resection of early primary nonampullary duodenal carcinoma, JOURNAL OF CLINICAL GASTROENTEROLOGY, 37(5), 381-386, 2003
  824. Somatic mutation in mitochondrial DNA and nuclear microsatellite instability in gastric cancer, ONCOLOGY REPORTS, 10(6), 1837-1841, 2003
  825. Helicobacter pylori infection influences expression of genes related to angiogenesis and invasion in human gastric carcinoma cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 311(4), 809-814, 20031128
  826. Expressions of angiogenic factors in pancreatic ductal carcinoma: A correlative study with clinicopathologic parameters and patient survival, PANCREAS, 26(4), 344-349, 200305
  827. Nodular gastritis in adults is caused by Helicobacter pylori infection, DIGESTIVE DISEASES AND SCIENCES, 48(5), 968-975, 200305
  828. PDE5 inhibitor sildenafil citrate augments endothelium-dependent vasodilation in smokers, HYPERTENSION, 41(5), 1106-1110, 200305
  829. Smoking activates Rho-kinase in smooth muscle cells of forearm vasculature in humans, HYPERTENSION, 41(5), 1102-1105, 200305
  830. A comparison of low-dose and standard-dose oral estrogen on forearm endothelial function in early postmenopausal women, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 88(3), 1303-1309, 200303
  831. Choleretic action of diosgenin is based upon the increases in canalicular membrane fluidity and transporter activity mediating bile acid independent bile flow, HEPATOLOGY RESEARCH, 25(3), 287-295, 200303
  832. Giant gastric folds: Differential diagnosis at US, RADIOLOGY, 226(3), 686-690, 200303
  833. Screening of genes specifically activated in the pancreatic juice ductal cells from the patients with pancreatic ductal carcinoma, CANCER SCIENCE, 94(3), 263-270, 200303
  834. Unique reciprocal changes of hepatocellular membrane transporter expression and fluidity in rats with selective biliary obstruction, HEPATOLOGY RESEARCH, 26(2), 157-163, 200306
  835. Long-term observation of reflux oesophagitis developing after Helicobacter pylori eradication therapy, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 17(12), 1529-1534, 20030615
  836. Expression of hypoxia-inducible factor-l alpha is associated with tumor vascularization in human colorectal carcinoma, INTERNATIONAL JOURNAL OF CANCER, 105(2), 176-181, 20030610
  837. Inhibition of cholesterol crystallization under bilirubin deconjugation: partial characterization of mechanisms whereby infected bile accelerates pigment stone formation, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1632(1-2), 48-54, 20030610
  838. Expression of fibroblast growth factor receptor genes in human hepatoma-derived cell lines, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 39(7), 321-328, 2003
  839. Hypoxia-inducible factor-1 alpha expression and angiogenesis in gastrointestinal stromal tumor of the stomach, ONCOLOGY REPORTS, 10(4), 797-802, 2003
  840. Natural histories of hepatitis C virus infection in men and women simulated by the Markov model, JOURNAL OF MEDICAL VIROLOGY, 70(3), 378-386, 200307
  841. Cardiac angiotensin II type 2 receptor activates the kinin/NO system and inhibits fibrosis, HYPERTENSION, 41(1), 99-107, 200301
  842. Hydrophilic bile salts have a cytoprotective effect against cyclosporine A-induced cholestasis through enhanced canalicular membrane fluidity and transporter activity, HEPATOLOGY RESEARCH, 25(1), 38-47, 200301
  843. Autonomic nerve dysfunction is closely associated with the abnormalities of esophageal motility in reflux esophagitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(2), 159-163, 200302
  844. Helicobacter pylori infection influences tumor growth of human gastric carcinomas, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(2), 153-158, 200302
  845. Impaired gallbladder mucosal function in aged gallstone patients suppresses gallstone recurrence after successful extracorporeal shockwave lithotripsy, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 18(2), 157-161, 200302
  846. Leptin causes nitric-oxide independent coronary artery vasodilation in humans, HYPERTENSION RESEARCH, 26(2), 147-152, 200302
  847. Small rectal carcinoid with lymph node metastasis diagnosed prior to treatment, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 15(2), 195-197, 200302
  848. Promoter methylation of cyclin D2 gene in gastric carcinoma, INTERNATIONAL JOURNAL OF ONCOLOGY, 23(6), 1663-1670, 200312
  849. Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes, DIGESTIVE DISEASES AND SCIENCES, 48(12), 2315-2322, 200312
  850. Response of the left anterior descending coronary artery to Acetylcholine in patients with chest pain and angiographically normal coronary arteries, AMERICAN JOURNAL OF CARDIOLOGY, 92(12), 1394-1398, 20031215
  851. Mnk1 is required for angiotensin II - Induced protein synthesis in vascular smooth muscle cells, CIRCULATION RESEARCH, 93(12), 1218-1224, 20031212
  852. Myocardial bridging increases the risk of coronary spasm, CLINICAL CARDIOLOGY, 26(8), 377-383, 200308
  853. Somatic mutation of mitochondrial DNA in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 12(2), 169-174, 200308
  854. AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl4, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 308(1), 177-183, 20030815
  855. Comparison of forearm endothelial function between premenopausal and postmenopausal women with or without hypercholesterolemia, MATURITAS, 44(4), 307-315, 20030425
  856. Isolated granulomatous gastritis successfully treated by Helicobacter pylori eradication: a possible association between granulomatous gastritis and Helicobacter pylori, JOURNAL OF GASTROENTEROLOGY, 38(4), 371-375, 200304
  857. Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human gastric carcinomas, INTERNATIONAL JOURNAL OF ONCOLOGY, 22(4), 773-778, 200304
  858. Potential involvement of IL-8 and its receptors in the invasiveness of pancreatic cancer cells, INTERNATIONAL JOURNAL OF ONCOLOGY, 22(4), 765-771, 200304
  859. Serum pepsinogen concentration as a marker of Helicobacter pylori infection and the histologic grade of gastritis; evaluation of gastric mucosa by serum pepsinogen levels, JOURNAL OF GASTROENTEROLOGY, 38(4), 332-338, 200304
  860. Significance of an exaggerated meal-stimulated gastrin response in pathogenesis of Helicobacter pylori-negative duodenal ulcer, DIGESTIVE DISEASES AND SCIENCES, 48(4), 644-651, 200304
  861. Depressed-type, early duodenal carcinoma(carcinoma in situ) treated by endoscopic mucosal resection, J. Gastroenterol., 38(8), 813-815, 20030401
  862. Expression of hyposia-inducible factor-1 alpha is associated with tumor vascularization in human colorectal carcinoma, Int J Cancer, 105(2), 176-181, 20030401
  863. Expression of vascular endothelial growth facter and angiogenesis in gastrointestinal stromal tumor of the stomach, Oncology, 64(3), 266-274, 20030401
  864. Minute depressed colon cancer with submucosal invasion, Gastrointest Endosc, 57(4), 564-565, 20030401
  865. Nondular gastritis in adults is caused by Helicobacter pylori ingfection, Dig Dis Sci, 48(5), 968-975, 20030401
  866. Prominent J wave and ST segment elevation: Serial electrocardiographic changes in accidental hypothermia, Journal of cardiovasuclar electrophysiology, 14(2), 223, 20030401
  867. Clinical significance of angiogenic factor expression at the deepest invasive site of advanced colorectal carcinoma, ONCOLOGY, 64(1), 61-73, 2003
  868. Expression of vascular endothelial growth factor and angiogenesis in gastrointestinal stromal tumor of the stomach, ONCOLOGY, 64(3), 266-274, 2003
  869. Rare quasispecies in the YMDD motif of hepatitis B virus detected by polymerase chain reaction with peptide nucleic acid clamping, INTERVIROLOGY, 46(6), 355-361, 2003
  870. Combination therapy of low-dose medroxyprogesterone acetate and oral estrogen does not affect endothelial function in the forearms of postmenopausal women, MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 9(5), 360-366, 2002
  871. Determining depth of invasion by VN pit pattern analysis in submucosal colorectal carcinoma, ONCOLOGY REPORTS, 9(5), 1005-1008, 2002
  872. Clinical characteristics and natural history of patients with low-grade reflux esophagitis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 17(9), 949-954, 200209
  873. Combination of transcatheter arterial chemoembolization using cisplatin-lipiodol suspension and percutaneous ethanol injection for treatment of advanced small hepatocellular carcinoma, AMERICAN JOURNAL OF SURGERY, 184(3), 284-290, 200209
  874. Nicorandil-induced preconditioning as evidenced by troponin T measurements after coronary angioplasty in patients with stable angina pectoris, JAPANESE HEART JOURNAL, 43(5), 443-453, 200209
  875. Hormone replacement effects on endothelial function measured in the forearm resistance artery in normocholesterolemic and hypercholesterolemic postmenopausal women, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 87(10), 4634-4641, 200210
  876. Human telomerase reverse transcriptase, p53 and Ki-67 expression and apoptosis in colorectal serrated adenoma, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(10), 1194-1200, 200210
  877. Effect of alcohol consumption on endothelial function in men with coronary artery disease, ATHEROSCLEROSIS, 165(1), 145-152, 200211
  878. Irsogladine malate up-regulates gap junctional intercellular communication between pancreatic cancer cells via PKA pathway, PANCREAS, 25(4), 373-377, 200211
  879. Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human esophageal squamous cell carcinomas, INTERNATIONAL JOURNAL OF CANCER, 102(3), 220-224, 20021120
  880. Clinical significance of angiogenesis in rectal carcinoid tumors, ONCOLOGY REPORTS, 9(3), 489-494, 2002
  881. Balloon-occluded retrograde transvenous obliteration of gastric fundal varices with hemorrhage, AMERICAN JOURNAL OF ROENTGENOLOGY, 178(5), 1167-1174, 200205
  882. Implication of anti-parietal cell antibody levels in gastrointestinal diseases, including gastric carcinogenesis, DIGESTIVE DISEASES AND SCIENCES, 47(5), 1080-1085, 200205
  883. Preoperative assessment of gastric cancer vascularity by flash echo imaging, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(5), 608-612, 200205
  884. Severity of hypertension affects improved resistance artery endothelial function by angiotensin-converting enzyme inhibition, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 39(5), 668-676, 200205
  885. Cigarette smoking promotes atrophic gastritis in Helicobacter pylori-positive subjects, DIGESTIVE DISEASES AND SCIENCES, 47(3), 675-681, 200203
  886. Leptin causes vasodilation in humans, HYPERTENSION RESEARCH, 25(2), 161-165, 200203
  887. Role of anti-parietal cell antibody in Helicobacter pylori-associated atrophic gastritis: Evaluation in a country of high prevalence of atrophic gastritis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(3), 287-293, 200203
  888. Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia, HEART, 87(3), 264-269, 200203
  889. Management of chronic hepatitis C and prevention of hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY, 37, 69-73, 200206
  890. ★, Endothelial function and oxidative stress in renovascular hypertension, NEW ENGLAND JOURNAL OF MEDICINE, 346(25), 1954-1962, 20020620
  891. Evaluation of esophageal motility by endosonography using a miniature ultrasonographic probe in patients with reflux esophagitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(6), 674-678, 20020601
  892. Evaluation of gastric emptying measured with the C-13-octanoic acid breath test in patients with functional dyspepsia comparison with ultrasonography, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(6), 662-666, 20020601
  893. Preconditioning effect during coronary angioplasty in patients with stable angina pectoris, INTERNAL MEDICINE, 41(7), 509-515, 200207
  894. Renal endothelial dysfunction and hypertension, JOURNAL OF DIABETES AND ITS COMPLICATIONS, 16(1), 103-107, 2002
  895. Tetrahydrobiopterin improves coronary endothelial function, but does not prevent coronary spasm in patients with vasospastic angina, CIRCULATION JOURNAL, 66(1), 58-62, 200201
  896. Excess norepinephrine impairs both endothelium-dependent and -independent vasodilation in patients with pheochromocytoma, HYPERTENSION, 39(2), 513-518, 200202
  897. Helicobacter pylori infection increases serum nitrate and nitrite more prominently than serum pepsinogens, HELICOBACTER, 7(1), 9-13, 200202
  898. Serological comparison of serum pepsinogen and antiparietal cell antibody levels between Japanese and German patients, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 14(2), 123-127, 200202
  899. Estrogen replacement suppresses function of thrombin stimulated platelets by inhibiting Ca2+ influx and raising cyclic adenosine monophosphate, CARDIOVASCULAR RESEARCH, 53(3), 634-641, 20020215
  900. Less hydrophobic phosphatidylcholine species simplify biliary vesicle morphology, but induce bile metastability with a broad spectrum of crystal forms, BIOCHEMICAL JOURNAL, 362, 105-112, 20020215
  901. K-ras mutation in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer, INTERNATIONAL JOURNAL OF CANCER, 97(5), 562-566, 20020210
  902. Circadian variation of blood pressure and endothelial function in patients with essential hypertension: A comparison of dippers and non-dippers, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 40(11), 2039-2043, 20021204
  903. A frameshift mutation of beta subunit of epithelial sodium channel in a case of isolated Liddle syndrome, JOURNAL OF HYPERTENSION, 20(12), 2379-2382, 200212
  904. Mechanisms responsible for vasodilation upon magnesium infusion in vivo: Clinical evidence, MAGNESIUM RESEARCH, 15(3-4), 241-246, 200212
  905. Advanced colorectal carcinoma smaller than 10 mm in maximum diameter with special reference to clinicopathologic and molecular features: a report of 3 cases, GASTROINTESTINAL ENDOSCOPY, 56(2), 299-303, 200208
  906. Helicobacter pylori eradication therapy improves atrophic gastritis and intestinal metaplasia: a 5-year prospective study of patients with atrophic gastritis, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 16(8), 1449-1456, 200208
  907. A low-calorie diet improves endothelium-dependent vasodilation in obese patients with essential hypertension, AMERICAN JOURNAL OF HYPERTENSION, 15(4), 302-309, 200204
  908. High incidence of B-cell monoclonality in follicular gastritis: a possible association between follicular gastritis and MALT lymphoma, VIRCHOWS ARCHIV, 440(4), 376-380, 200204
  909. Long-term rebamipide therapy improves Helicobacter pylori-associated chronic gastritis, DIGESTIVE DISEASES AND SCIENCES, 47(4), 862-867, 200204
  910. Nicorandil enhances myocardial tolerance to ischemia without progressive collateral recruitment during coronary angioplasty, CIRCULATION JOURNAL, 66(4), 317-322, 200204
  911. Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals, AMERICAN JOURNAL OF HYPERTENSION, 15(4), 326-332, 200204
  912. Hepatic hydroxylation of bile acids and chronic liver diseases: do transporters play a mechanistic role?, 20020401
  913. Single administration of ecabet sodium diminishes the level of delta-(13) Co(2) in urea breath test, J GastroenterolM., 37(8), 674-675, 20020401
  914. Clinical significance of vascular endothelial growth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma, ONCOLOGY, 62(2), 157-166, 2002
  915. Pathogenic significance and organic virus levels in patients infected with TT virus, INTERVIROLOGY, 44(5), 291-297, 2001
  916. A low C-13-urea breath test value is associated with increased risk of gastric cancer, JOURNAL OF GASTROENTEROLOGY, 36(9), 601-605, 200109
  917. Expression of telomeric repeat binding factor 1 and 2 and TRF1-interacting nuclear protein 2 in human gastric carcinomas, INTERNATIONAL JOURNAL OF ONCOLOGY, 19(3), 507-512, 200109
  918. Randomized controlled clinical trial of lymphoblastoid interferon-alpha for chronic hepatitis C, HEPATOLOGY RESEARCH, 21(1), 55-66, 200109
  919. Clinicopathological significance of vascular endothelial growth factor (VEGF)-C in human esophageal squamous cell carcinomas, INTERNATIONAL JOURNAL OF CANCER, 93(5), 662-666, 20010901
  920. Calorie restriction reduced blood pressure in obesity hypertensives by improvement of autonomic nerve activity and insulin sensitivity, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 38, S69-S74, 200110
  921. Effect of obesity on endothelium-dependent, nitric oxide-mediated vasodilation in normotensive individuals and patients with essential hypertension, AMERICAN JOURNAL OF HYPERTENSION, 14(10), 1038-1045, 200110
  922. MUC1 and cathepsin D expression in early colorectal carcinoma showing V type pit pattern, INTERNATIONAL JOURNAL OF ONCOLOGY, 19(4), 665-672, 200110
  923. Extracorporeal ultrasound is an effective diagnostic alternative to endoscopic ultrasound for gastric submucosal tumours, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 36(11), 1222-1226, 200111
  924. Sodium chloride loading does not alter endothelium-dependent vasodilation of forearm vasculature in either salt-sensitive or salt-resistant patients with essential hypertension, HYPERTENSION RESEARCH, 24(6), 711-716, 200111
  925. Microsatellite instability is a genetic marker for the development of multiple gastric cancers, INTERNATIONAL JOURNAL OF CANCER, 95(6), 350-353, 20011120
  926. Usefulness of flow-mediated dilation of the brachial artery and/or the intima-media thickness of the carotid artery in predicting coronary narrowing in patients suspected of having coronary artery disease, AMERICAN JOURNAL OF CARDIOLOGY, 88(10), 1147-1151, 20011115
  927. Bile-salt hydrophobicity is a key factor regulating rat liver plasma-membrane communication: relation to bilayer structure, fluidity and transporter expression and function, BIOCHEMICAL JOURNAL, 359, 605-610, 20011101
  928. Reduction in the incidence of Helicobacter pylori-associated carcinoma in Japanese young adults, ONCOLOGY REPORTS, 8(3), 633-636, 2001
  929. Is a role of phospholipase A(2) in cholesterol gallstone formation phospholipid species-dependent?, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1532(1-2), 51-59, 20010531
  930. Non-dipper phenomenon in essential hypertension is related to blunted nocturnal rise and fall of sympatho-vagal nervous activity and progress in retinopathy, AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, 88(3), 181-186, 20010514
  931. c-myc gene mutation in gastric mucose-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphoma, ONCOLOGY REPORTS, 8(2), 289-292, 2001
  932. Microsatellite instability at D18S61 is associated with no regression of gastric mucosa-associated lymphoid tissue lymphoma after Helicobacter pylori eradication, ONCOLOGY REPORTS, 8(2), 293-297, 2001
  933. Cyclosporin A reduces canalicular membrane fluidity and regulates transporter function in rats, BIOCHEMICAL JOURNAL, 354, 591-596, 20010315
  934. Dose-dependent conjugation of sulfobromophthalein and hepatic transit time in bile fistula rats - Role of the microtubule-dependent vesicle pathway, DIGESTIVE DISEASES AND SCIENCES, 46(6), 1285-1289, 200106
  935. Evaluation of quantitative measurements of hepatitis C virus RNA to predict sustained response to interferon by genotype, JOURNAL OF VIROLOGICAL METHODS, 95(1-2), 33-45, 200106
  936. Helicobacter pylori eradication therapy for high-grade mucosa-associated lymphoid tissue lymphomas of the stomach with analysis of p53 and K-ras alteration and microsatellite instability, INTERNATIONAL JOURNAL OF ONCOLOGY, 18(6), 1207-1212, 200106
  937. Risk factors of hepatitis C virus-related liver cirrhosis in young adults: Positive family history of liver disease and transporter associated with antigen processing 2 (TAP2)*0201 allele, JOURNAL OF MEDICAL VIROLOGY, 64(2), 109-116, 200106
  938. Clinicopathologic features and endoscopic treatment of superficially spreading colorectal neoplasms larger than 20 mm, GASTROINTESTINAL ENDOSCOPY, 54(1), 62-66, 200107
  939. Clinicopathological features of gastric mucosa-associated lymphoid tissue lymphoma: A comparison with diffuse large B-cell lymphoma without a mucosa-associated lymphoid tissue lymphoma component, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 16(7), 734-739, 200107
  940. Effect of estrogen replacement therapy on endothelial function in peripheral resistance arteries in normotensive and hypertensive postmenopausal women, HYPERTENSION, 37(2), 651-657, 200102
  941. Lamivudine therapy for spontaneously occurring severe acute exacerbation in chronic hepatitis B virus infection: A preliminary study, AMERICAN JOURNAL OF GASTROENTEROLOGY, 96(2), 557-562, 200102
  942. Does bilirubin play a role in the pathogenesis of both cholesterol and pigment gallstone formation? Direct and indirect influences of bilirubin on bile lithogenicity, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1534(2-3), 78-84, 20011230
  943. Endothelial dysfunction is an independent factor responsible for vasospastic angina, CLINICAL SCIENCE, 101(6), 707-713, 200112
  944. Interleukin 8 and vascular endothelial growth factor - prognostic factors in human gastric carcinomas?, EUROPEAN JOURNAL OF CANCER, 37(12), 1482-1487, 200108
  945. Nonselective cation channel as a Ca2+ influx pathway in pepsinogen-secreting cells of bullfrog esophagus, AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 281(2), G333-G341, 200108
  946. Angiotensin II type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin II type 1 receptor antagonist, FEBS LETTERS, 495(3), 197-200, 20010427
  947. Angiotensin (]G0002[) type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin (]G0002[) type 1 receptor antagonist, FEBS Lett, 495, 197-200, 20010401
  948. Diagnosis of invasion depth in early colorectal carcinoma by pit pattern analysis with magnifying endoscopy, Digestive Endoscopy, 13, S2-S5, 20010401
  949. Effect of for antihypertensives on reactive hypermia in essential hypertension, Cardiology Review, 18(4), 31-39, 20010401
  950. Efficacy of IFN therapy based on duration period of negative HCV-RNA during IFN administration, Hepatol Res, 19, 22-300, 20010401
  951. Long-term interferon therapy for 1 year or longer reduces the hepatocellular carcinogenesis rate in patients with liver cirrhosis caused by hepatitis C virus: a pilot study, J Gastroenterol Hepatol., 16(4), 406-415, 20010401
  952. Risk factors of hepatitis C virus-related liver cirrhosis in young adults: positive family history of liver disease and transporter associated with antigen processing 2(TAP2)*0201 Allele., J Med Virol, 64, 109-116, 20010401
  953. Twice-daily administration of interferon-beta for chronic hepatitis C is not superior to a once-daily regimen, J. Gastroenterol, 36, 242-247, 20010401
  954. Activation of peroxisome proliferator-activated receptor gamma inhibits the growth of human pancreatic cancer, PATHOBIOLOGY, 69(5), 258-265, 2001
  955. Expression of MRE11 complex (MRE11, RAD50, NBS1) and hRap1 and its relation with telomere regulation, telomerase activity in human gastric carcinomas, PATHOBIOLOGY, 69(4), 219-224, 2001
  956. Association of amino acid sequence in the PKR-eIF2 phosphorylation homology domain and response to interferon therapy, HEPATOLOGY, 32(5), 1138-1144, 200011
  957. Distinction between chronic hepatitis and liver cirrhosis in patients with hepatitis C virus infection. Practical discriminant function using common laboratory data, Hepatol Res, 18(3), 252-266, 20000401
  958. Fluctuation patterns of HCV-RNA serum level in patients with chronic hepatitis C, J. Gastroenterol., 35(3), 221-225, 20000401
  959. Incidence of primary liver cancer-cholangiocellular type in Japanese patients with hepatitis C virus related cirrhosis, Cancer, 88, 2471-2477, 20000401
  960. Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor-A prospective randomized study of hepatitis C virus-related liver cancer., Hepatology, 32(2), 436-438, 20000401
  961. Progressive and sufficient decrease of hepatitis B core antibody can predict the disappearance of hepatitis B virus DNA in Japanese patients with hepatitis B surface antigen clearance, J. Gastroenterol., 35(10), 753-757, 20000401
  962. Relationship between five-year histological outcome and serial changes in serum alanine aminotransferase in patients with biochemical and virological relapse after interferon treatment for chronic hepatitis C, Intervirol, 43, 174-179, 20000401
  963. A device for simultaneous application of sclerotherapy and endoscopic ligation for management of esophageal varices, Dig.Endosc, 11, 363-365, 19990401
  964. Chronic liver disease in the extremely elderly of 80 years or more: clinical characteristics, prognosis and patient survival analysis, J Hepatol, 31, 860-866, 19990401
  965. Clinical and virological features of chronic hepatitis C carriers with normal alanine aminotransferase levels despite positive serum HCV-RNA after interferon therapy, J. Gastroenterol., 34, 594-599, 19990401
  966. Combined ursodeoxycholic acid glycyrrhizin therapy for chronic hepatitis C virus infection: a randomized controlled trial in 170 patients, Eur J Gastroen Hepat, 11, 1077-1083, 19990401
  967. Effect of arterial administration of a high-molecular weight antitumor agent,styrene maleic acid neocarzinostatin,in embolization-resistant liver cancer, Int. J. Clin. Oncol., 14, 148-155, 19990401
  968. Effect of interferon therapy on hepatocellular carcinogenesis in patients with chronic hepatitis type C: A long-term observation study of 1,643 patients using statistical bias correction with proportional hazard analysis, Hepatology, 29(4), 1124-1130, 19990401
  969. Efficacy and changes of the nonstructural 5A gene by prolonged interferon therapy for patients with hepatitis C virus (HCV) genotype1b and a high level of serum HCV-RNA, Intern Med, 38, 19990401
  970. Enzyme-linked immunosorbent assay to detect hepatitis C virus serological groups 1to 6, J. Gastroenterol., 34, 505-509, 19990401
  971. Fluctuations of hepatitis C virus load are not related to amino acid substitutions in hypervariable region 1 and interferon sensitivity determining region, J Med Virol, 58, 247-255, 19990401
  972. Histological changes in liver biopsies after one year of lamivudine treatment in patients with chronic hepatitis B infection, J Hepatol, 30, 743-748, 19990401
  973. Prevalence of TT virus before and after blood transfusion in patients with chronic liver disease treated surgically for hepatocellular carcinoma, J Gastroenterol Hepatol., 14, 358-363, 19990401
  974. Susceptibility of TT virus to interferon therapy, J. Gen. Virol., 80, 631-634, 19990401
  975. Time course of histological changes in patients with a sustained biochemical and virological response to corticosteroid withdrawal therapy for chronic hepatitis B, Am J Gastroenterol, 94, 3304-3309, 19990401
  976. A randomized controlled trial of interferon-alpha in patients with cirrhosis caused by 2a/2b genotype hepatitis C virus, J Hepatol, 27(5), 910-912, 19980401
  977. Biochemical and histological features of hepatitis G virus infection, J Gastroenterol Hepatol., 13, 767-772, 19980401
  978. Deletions in the hepatitis B virus core gene may influence the clinical outcome in hepatitis B e antigen-positive asymptomatic healthy carriers., Journal of Medical Virology, 56, 287-293, 19980401
  979. Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients, J Hepatol, 28, 930-938, 19980401
  980. Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy., Hepatology, 27, 1711-1716, 19980401
  981. Glomerulonephritis in autopsy cases with hepatitis C virus infection, Internal Med., 37(10), 836-840, 19980401
  982. Interferon decreases hepatocellular carcinogenesis in patients with cirrhosis caused by the hepatitis B virus-A pilot study, Cancer, 82(5), 827-835, 19980401
  983. Predictive factors in eradicating hepatitis C virus using a relatively small dose of interferon, J Gastroenterol Hepatol., 13, 412-418, 19980401
  984. Relationship of angiographic finding with neovascular structure detected by immunohistochemical staining of alpha-smooth muscle action in small hepatocellular carcinoma, J Gastroenterol Hepatol., 13, 1266-1273, 19980401
  985. Relationship of hepatocellular carcinogenesis with precore mutant virus and serum hepatitis B virus DNA concentration. A longitudinal analysis of patients with cirrhosis, Hepatol Res, 10, 142-155, 19980401
  986. Usefulness of hepatitis C virus RNA counts by second generation HCV bDNA-probe in chronic hepatitis C based on the HCV genotype, J. Gastroenterol., 33(2), 223-228, 19980401
  987. A prospective randomized administration of 5'-deoxy-5-fluorouridine as adjuvant chemotherapy for hepatocellular carcinoma treated with transcatheter arterial chemoembolization., Am. J. Clin. Oncol., 20(2), 202-208, 19970401
  988. Effect of arterial administration of a high molecular weight anti-tumor agent, styrene maleic acid neocarzinostain, for multiple small liver cancer-A pilot study, J. Gastroenterol., 32, 513-520, 19970401
  989. Effect of interferon therapy on viral titers in patients with chronic hepatitis C who are positive for hepatitis GB virus C, J Hepatol, 26, 769-770, 19970401
  990. Hepatitis G virus infection after blood transfusion in patients with chronic liver disease treated surgically for hepatocellular carcinoma, Hepatol Res, 9(1), 28-36, 19970401
  991. Nucleotide sequences of hepatitis GB virus C. Identification of highly conserved domains in the 5' noncoding region and detection by polymerase chain reaction, Int Hepatol Commun, 6, 225-232, 19970401
  992. Pretreatment virus load and multiple amino acid substitutions in the interferon sensitivity-determining region predict the outcome of interferon treatment in patients with chronic genotype 1b hepatitis C virus infection, Hepatology, 25, 745-749, 19970401
  993. The long term efficacy of glycyrrhizin in chronic hepatitis C patients, Cancer, 79(8), 1494-1500, 19970401
  994. The superiority of laparoscopic examination in predicting hepatocellular carcinoma after interferon therapy for chronic type C hepatitis, Dig.Endosc, 9(1), 29-33, 19970401
  995. Time course of histological changes in patients with a sustained biochemical and virological response to interferon-alpha therapy for chronic hepatitis C virus infection., J Hepatol, 27(1), 49-55, 19970401
  996. A pilot study of corticosteroid priming for lymphoblastoid interferon alpha in patients with chronic hepatitis C, Hepatology, 23, 953-957, 19960401
  997. Hepatitis C virus subtype 3b infection in a hospital in Japan: Epidemiological study, J. Gastroenterol., 31(6), 801-805, 19960401
  998. Relationship between pretreatment viremia level and response to interferon alpha therapy in chronic hepatitis C differs in viral type 1 and 2 infections, Digest Dis Sci, 41(10), 1925-1932, 19960401
  999. Typing six major hepatitis C virus genotypes by polymerase chain reaction using primers derived from nucleotide sequences of the NS5 region, Int Hepatol Commun, 4, 263-267, 19960401
  1000. A prospective randomized evaluation of a compound of Tegafur and Uracil as an adjuvant chemotherapy for hepatocellular carcinoma treated with transcatheter arterial chemoembolization, Am. J. Clin. Oncol., 18(3), 204-210, 19950401
  1001. Diagnosis of hepatocellular carcinoma by concanavalin A affinity electrophoresis of serum alpha-fetoprotein, Cancer, 76(3), 1139-1144, 19950401
  1002. Serial hemodynamic measurements in well-differentiated hepatocellular carcinomas, Hepatology, 21(6), 1530-1534, 19950401
  1003. Usefulness of HCV-RNA counts by the method of HCV-bDNA probe in interferon retreatment for patients with HCV-RNA positive chronic hepatitis C, Int Hepatol Commun, 4(1), 19-25, 19950401
  1004. Antiviral effect of lymphoblastoid IFN-alpha on hepatitis C virus in patients with chronic hepatitis type C, J Gastroen Hepatol, 9, 128-133, 19940401
  1005. Imaging diagnosis of small hepatocellular carcinoma, Hepatology, 20(1), 82-87, 19940401
  1006. Interferon retreatment of nonresponders with HCV-RNA-positive chronic hepatitis C, J. Gastroenterol., 29, 299-304, 19940401
  1007. Nucleotide sequence of hepatitis C virus (type 3b) isolated from a Japanese patient with chronic hepatitis C, J. Gen. Virol., 75, 3623-3628, 19940401
  1008. Prevalence of HCV genotype among patients with chronic liver disease in the Tokyo metropolitan area, J. Gastroenterol., 29, 583-587, 19940401
  1009. Serum des-gamma-carboxyprothrombin concentration determined by the avidin-biotin complex method in small hepatocellular carcinomas, Cancer, 74(11), 2918-2923, 19940401
  1010. Small hepatocellular carcinoma: evaluation of portal blood flow with CT during arterial portography performed with balloon occlusion of the hepatic artery, Radiology, 193, 67-70, 19940401
  1011. The HCV-bDNA probe method for measurement of HCV-RNA counts by HCV genotype, Int Hepatol Commun, 2, 213-217, 19940401
  1012. A proposed system for the nomenclature of hepatitis C viral genotypes., 19940101
  1013. Factors predictive of response to interferon-alpha therapy in hepatitis C virus infection., 19940101
  1014. A multivariate analysis of risk factors for hepatocellular carcinogenesis- A prospective observation of 795 patients with viral and alcoholic cirrhosis, Hepatology, 18(1), 47-53, 19930401
  1015. Diagnosis and follow-up of small hepatocellular carcinoma with selective intraarterial digital subtraction angiography, Hepatology, 17(6), 1003-1007, 19930401
  1016. Effect of lymphoblastoid alfa-interferon in patients with chroni chepatitis C having different genotypic subtype of hepatitis C virus, Gastroenterologia Japonica, 28, 45-47, 19930401
  1017. Factors useful in predicting the response to interferon therapy in chronic hepatitis C, J Gastroen Hepatol, 8, 535-539, 19930401
  1018. Genotypic subtyping of hepatitis C virus, J Gastroenterol Hepatol., 8, 150-156, 19930401
  1019. Risk factors for tumor recurrence and prognosis after curative resection of hepatocellular carcinoma, Cancer, 71(1), 19-25, 19930401
  1020. Alanine aminotransferase and HCV-RNA responses following interferon therapy of HCV-RNA positive chronic hepatitis, Gastroenterologia Japonica, 27(5), 646-651, 19920401
  1021. Effect of interferon administration on serum hepatitis C virus RNA in patients with chronic hepatitis C, Hepatology, 13(6), 1040-1043, 19910401
  1022. Effect of repeated transcatheter arterial embolization on the survival time in patients with hepatocellular carcinoma. An analysis by the proportional hazard model, Cancer, 68(10), 2150-2154, 19910401
  1023. Phyllodes tumor of the prostate: A case report, 19, 299-304, 19890301
  1024. Diagnostic performance of Japan NBI Expert Team classification for differentiation among noninvasive, superficially invasive, and deeply invasive colorectal neoplasia, GASTROINTESTINAL ENDOSCOPY, 86(4), 700-709, 201710
  1025. Emergence of drug resistance-associated variants and changes in serum lipid profiles in sofosbuvir plus ledipasvir-treated chronic hepatitis C patients, JOURNAL OF MEDICAL VIROLOGY, 89(11), 1963-1972, 201711
  1026. Endothelial Function Is Impaired in Patients Receiving Antihypertensive Drug Treatment Regardless of Blood Pressure Level FMD-J Study (Flow-Mediated Dilation Japan), HYPERTENSION, 70(4), 790-+, 201710
  1027. Clinical features and predictive value of serum inflammatory markers of perivascular involvement in immunoglobulin G4-related disease, HEART AND VESSELS, 32(10), 1176-1185, 201710
  1028. Three patients treated with sofosbuvir plus ledipasvir for recurrent hepatitis C after liver transplantation, CLINICAL JOURNAL OF GASTROENTEROLOGY, 10(2), 179-184, 201704
  1029. Late-onset ornithine transcarbamylase deficiency associated with hyperammonemia, CLINICAL JOURNAL OF GASTROENTEROLOGY, 10(4), 383-387, 201708
  1030. Long-term outcomes after treatment for T1 colorectal carcinoma: a multicenter retrospective cohort study of Hiroshima GI Endoscopy Research Group, JOURNAL OF GASTROENTEROLOGY, 52(11), 1169-1179, 201711
  1031. Clinical impact of surveillance colonoscopy using magnification without diminutive polyp removal, DIGESTIVE ENDOSCOPY, 29(7), 773-781, 201711
  1032. Wisteria floribunda agglutinin positive Mac-2-binding protein level increases in patients with acute liver injury, JOURNAL OF GASTROENTEROLOGY, 52(12), 1252-1257, 201712
  1033. A case of large cell neuroendocrine carcinoma of the stomach with multiple liver metastases, Nihon Shokakibyo Gakkai Zasshi, 113(8), 1393-1400, 20160809
  1034. Evaluation of antiviral effect of type I, II, and III interferons on direct-acting antiviral-resistant hepatitis C virus, ANTIVIRAL RESEARCH, 146, 130-138, 201710
  1035. H558R, a common SCN5A polymorphism, modifies the clinical phenotype of Brugada syndrome by modulating DNA methylation of SCN5A promoters, JOURNAL OF BIOMEDICAL SCIENCE, 24, 20171204
  1036. Resistance characterization of hepatitis C virus genotype 2 from Japanese patients treated with ombitasvir and paritaprevir/ritonavir, JOURNAL OF MEDICAL VIROLOGY, 90(1), 109-119, 201801
  1037. Hepatitis B Virus Evades Innate Immunity of Hepatocytes but Activates Cytokine Production by Macrophages, HEPATOLOGY, 66(6), 1779-1793, 201712
  1038. Clinicopathologic and endoscopic features of early-stage colorectal serrated adenocarcinoma, BMC GASTROENTEROLOGY, 17, 20171212
  1039. Polysaccharides derived from Ganoderma lucidum fungus mycelia ameliorate indomethacin-induced small intestinal injury via induction of GM-CSF from macrophages, CELLULAR IMMUNOLOGY, 320, 20-28, 201710
  1040. Daclatasvir and asunaprevir in hemodialysis patients with hepatitis C virus infection: a nationwide retrospective study in Japan, JOURNAL OF GASTROENTEROLOGY, 53(1), 119-128, 201801
  1041. Characterization of Recombinant Flaviviridae Viruses Possessing a Small Reporter Tag, JOURNAL OF VIROLOGY, 92(2), 201801
  1042. Brachial artery diameter as a marker for cardiovascular risk assessment: FMD-J study, ATHEROSCLEROSIS, 268, 92-98, 201801
  1043. Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy, JOURNAL OF GASTROENTEROLOGY, 53(1), 107-118, 201801
  1044. Efficacy and safety of edoxaban for treatment of portal vein thrombosis following danaparoid sodium in patients with liver cirrhosis, HEPATOLOGY RESEARCH, 48(1), 51-58, 201801
  1045. Hepatocellular carcinoma treated with sorafenib: Arterial tumor perfusion in dynamic contrast-enhanced CT as early imaging biomarkers for survival, EUROPEAN JOURNAL OF RADIOLOGY, 98, 41-49, 201801
  1046. Efficacy and safety of telaprevir with natural human interferon-beta and ribavirin in Japanese chronic hepatitis C patients with depression, HEPATOLOGY RESEARCH, 48(2), 184-192, 201802
  1047. Clinical outcomes of stereotactic body radiotherapy for elderly patients with hepatocellular carcinoma, HEPATOLOGY RESEARCH, 48(2), 193-204, 201802
  1048. Integrated Resistance Analysis of CERTAIN-1 and CERTAIN-2 Studies in Hepatitis C Virus-Infected Patients Receiving Glecaprevir and Pibrentasvir in Japan, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 62(2), 201802
  1049. Combinational use of hepatitis B viral antigens predicts responses to nucleos(t)ide analogue/peg-interferon sequential therapy, JOURNAL OF GASTROENTEROLOGY, 53(2), 247-257, 201802
  1050. Involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 53(2), 269-280, 201802
  1051. Efficacy and safety of glecaprevir/pibrentasvir in Japanese patients with chronic genotype 2 hepatitis C virus infection, HEPATOLOGY, 67(2), 505-513, 201802
  1052. Chronic kidney disease is associated with vascular smooth muscle dysfunction but not with endothelial dysfunction, INTERNATIONAL JOURNAL OF CARDIOLOGY, 254, 284-290, 20180301
  1053. Serial profiling of circulating tumor DNA for optimization of anti-VEGF chemotherapy in metastatic colorectal cancer patients, INTERNATIONAL JOURNAL OF CANCER, 142(7), 1418-1426, 20180401
  1054. Clinical outcomes of endoscopic submucosal dissection for colorectal tumors: a large multicenter retrospective study from the Hiroshima GI Endoscopy Research Group, GASTROINTESTINAL ENDOSCOPY, 87(3), 714-722, 201803
  1055. Risk factors for exacerbation of gastroesophageal varices and portosystemic encephalopathy during treatment with nucleos(t)ide analogs for hepatitis B virus-related cirrhosis, HEPATOLOGY RESEARCH, 48(4), 264-274, 201803
  1056. Clinical significance of small-bowel villous edema in patients with liver cirrhosis: A capsule endoscopy study, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 33(4), 825-830, 201804
  1057. Interrelationships Among Flow-Mediated Vasodilation, Nitroglycerine-Induced Vasodilation, Baseline Brachial Artery Diameter, Hyperemic Shear Stress, and Cardiovascular Risk Factors, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 7(1), 201801
  1058. Efficacy and safety of ledipasvir/sofosbuvir with ribavirin in chronic hepatitis C patients who failed daclatasvir/asunaprevir therapy: pilot study, JOURNAL OF GASTROENTEROLOGY, 53(4), 548-556, 201804
  1059. Efficacy and safety of glecaprevir/pibrentasvir in Japanese patients with chronic genotype 1 hepatitis C virus infection with and without cirrhosis, JOURNAL OF GASTROENTEROLOGY, 53(4), 557-565, 201804
  1060. Comparison of Outcome of Hepatic Arterial Infusion Chemotherapy Combined with Radiotherapy and Sorafenib for Advanced Hepatocellular Carcinoma Patients with Major Portal Vein Tumor Thrombosis, ONCOLOGY, 94(4), 215-222, 2018
  1061. Efficacy and safety of glecaprevir/pibrentasvir in HCV-infected Japanese patients with prior DAA experience, severe renal impairment, or genotype 3 infection, JOURNAL OF GASTROENTEROLOGY, 53(4), 566-575, 201804
  1062. Taking Warfarin with Heparin Replacement and Direct Oral Anticoagulant Is a Risk Factor for Bleeding after Endoscopic Submucosal Dissection for Early Gastric Cancer, DIGESTION, 97(3), 240-249, 2018
  1063. Evaluation of glycemic variability in chronic liver disease patients with type 2 diabetes mellitus using continuous glucose monitoring, PLOS ONE, 13(4), 20180403
  1064. Reactive hyperemia-peripheral arterial tonometry is useful for assessment of not only endothelial function but also stenosis of the digital artery, INTERNATIONAL JOURNAL OF CARDIOLOGY, 260, 178-183, 20180601
  1065. miR-135a-5p-mediated downregulation of protein tyrosine phosphatase receptor delta is a candidate driver of HCV-associated hepatocarcinogenesis, GUT, 67(5), 953-962, 201805
  1066. Endothelial dysfunction, abnormal vascular structure and lower urinary tract symptoms in men and women, INTERNATIONAL JOURNAL OF CARDIOLOGY, 261, 196-203, 20180615
  1067. Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations, JOURNAL OF HEPATOLOGY, 68(5), 959-969, 201805
  1068. Indication and Usefulness of Bile Juice Cytology for Diagnosis of Gallbladder Cancer, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2018
  1069. Persistent Loss of Hepatitis B Virus Markers in Serum without Cellular Immunity by Combination of Peginterferon and Entecavir Therapy in Humanized Mice, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61(9), 201709
  1070. HCV kinetic and modeling analyses project shorter durations to cure under combined therapy with daclatasvir and asunaprevir in chronic HCV-infected patients, PLOS ONE, 12(12), 20171207
  1071. Evaluation of the visibility of early gastric cancer using linked color imaging and blue laser imaging, BMC GASTROENTEROLOGY, 17, 20171208
  1072. Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 500(2), 152-157, 20180602
  1073. Pedunculated-type T1 colorectal carcinoma with lung carcinoma metastasis at the deepest invasive portion, CLINICAL JOURNAL OF GASTROENTEROLOGY, 9(4), 208-214, 201608
  1074. Detectability and clinical significance of serum hepatitis B virus ribonucleic acid, HEPATOBILIARY SURGERY AND NUTRITION, 4(3), 197-202, 201506
  1075. Curative Criteria After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinomas, DIGESTIVE DISEASES AND SCIENCES, 63(6), 1605-1612, 201806
  1076. Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction, PLOS ONE, 13(5), 20180521
  1077. Preclinical Pharmacological Development of Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection, JOURNAL OF INFECTIOUS DISEASES, 217(11), 1761-1769, 20180601
  1078. Cost-effectiveness analyses of anti-hepatitis C virus treatments using quality of life scoring among patients with chronic liver disease in Hiroshima prefecture, Japan, HEPATOLOGY RESEARCH, 48(7), 509-520, 201806
  1079. Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts the development of hepatocellular carcinoma in patients with non-alcoholic fatty liver disease, HEPATOLOGY RESEARCH, 48(7), 521-528, 201806
  1080. Silencing of Discoidin Domain Receptor-1 (DDR1) Concurrently Inhibits Multiple Steps of Metastasis Cascade in Gastric Cancer, TRANSLATIONAL ONCOLOGY, 11(3), 575-584, 201806
  1081. Hepatic arterial infusion chemotherapy followed by sorafenib in patients with advanced hepatocellular carcinoma (HICS 55): an open label, non-comparative, phase II trial, BMC CANCER, 18, 20180604
  1082. New assessment of endothelial function measured by short time flow-mediated vasodilation: Comparison with conventional flow-mediated vasodilation measurement, INTERNATIONAL JOURNAL OF CARDIOLOGY, 265, 24-29, 20180815
  1083. Predictive Factors of Portal Hypertensive Enteropathy Exacerbation in Patients with Liver Cirrhosis: A Capsule Endoscopy Study, DIGESTION, 98(1), 33-40, 2018
  1084. Clinical Significance of Reddish Depressed Lesions Observed in the Gastric Mucosa after Helicobacter pylori Eradication, DIGESTION, 98(1), 48-55, 2018
  1085. Long-term follow-up of clinical trial patients treated for chronic HCV infection with daclatasvir-based regimens, LIVER INTERNATIONAL, 38(5), 821-833, 201805
  1086. In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors, GENOME RESEARCH, 28(5), 654-665, 201805
  1087. Use of anticoagulants increases risk of bleeding after colorectal endoscopic submucosal dissection, ENDOSCOPY INTERNATIONAL OPEN, 6(7), E857-E864, 201807
  1088. Watch-and-wait policy versus rituximab-combined chemotherapy in Japanese patients with intestinal follicular lymphoma, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 33(8), 1461-1468, 201808
  1089. Long-term outcome of stereotactic body radiotherapy for patients with small hepatocellular carcinoma, HEPATOLOGY RESEARCH, 48(9), 701-707, 201808
  1090. Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure, JOURNAL OF GENERAL VIROLOGY, 99(8), 1058-1065, 201808
  1091. A Data Mining-based Prognostic Algorithm for NAFLD-related Hepatoma Patients: A Nationwide Study by the Japan Study Group of NAFLD, SCIENTIFIC REPORTS, 8, 20180711
  1092. Sofosbuvir-velpatasvir plus ribavirin in Japanese patients with genotype 1 or 2 hepatitis C who failed direct-acting antivirals, HEPATOLOGY INTERNATIONAL, 12(4), 356-367, 201807
  1093. Hepatectomy versus stereotactic body radiotherapy for primary early hepatocellular carcinoma: A propensity-matched analysis in a single institution, SURGERY, 164(2), 219-226, 201808
  1094. Acute hepatitis B virus infection in humanized chimeric mice has multiphasic viral kinetics, HEPATOLOGY, 68(2), 473-484, 201808
  1095. Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection, JOURNAL OF GASTROENTEROLOGY, 53(9), 1089-1097, 201809
  1096. Short-term outcomes of endoscopic submucosal dissection for superficial cecal tumors: a comparison between extension and nonextension into the appendiceal orifice, THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 11, 20180501
  1097. Management of occult obscure gastrointestinal bleeding patients based on long-term outcomes, THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 11, 20180716
  1098. Clinical outcomes of sorafenib treatment failure for advanced hepatocellular carcinoma and candidates for regorafenib treatment in real-world practice, HEPATOLOGY RESEARCH, 48(10), 814-820, 201809
  1099. Comparison of clinical outcome of hepatic arterial infusion chemotherapy and sorafenib for advanced hepatocellular carcinoma according to macrovascular invasion and transcatheter arterial chemoembolization refractory status, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 33(10), 1780-1786, 201810
  1100. Maintenance of low inflammation level by the ZFHX3 SNP rs2106261 minor allele contributes to reduced atrial fibrillation recurrence after pulmonary vein isolation, PLOS ONE, 13(9), 20180904
  1101. The IL28B SNP has a stronger regulatory effect on the expression of OAS1 than a nearby SNP located downstream of OAS1 in chronic HCV patients, HEPATOLOGY, 60, 1077A-1077A, 2014
  1102. Pretreatment induction of ISGs in the presence of IFNL4 in hepatocytes but not in white blood cells is related with poor induction of ISGs following IFN-alpha therapy, HEPATOLOGY, 60, 1077A-1078A, 2014
  1103. Hepatocellular carcinoma development of hepatitis C virus patients with eradication to interferon therapy: a large scale, long-term study of 2266 patients, HEPATOLOGY, 60, 1162A-1163A, 2014
  1104. Type 2 diabetes mellitus is associated with the fibrosis severity in patients with nonalcoholic fatty liver disease in a large retrospective cohort of Japanese patients, JOURNAL OF GASTROENTEROLOGY, 49(11), 1477-1484, 2014
  1105. Usefulness of transabdominal ultrasonography for improved safety of capsule endoscopy in patients with crohn's disease, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29, 89-89, 2014
  1106. Endocannabinoid CB1 antagonists inhibit hepatitis C virus production, providing a novel class of antiviral host-targeting agents, JOURNAL OF GENERAL VIROLOGY, 95, 2468-2479, 2014
  1107. Clinical outcome and prognostic factors of patients with hepatocellular carcinoma and extrahepatic metastasis treated with sorafenib, HEPATOLOGY RESEARCH, 44(13), 1320-1328, 2014
  1108. Impact of alloimmune T cell responses on hepatitis C virus replication in liver transplant recipients, HUMAN IMMUNOLOGY, 75(12), 1259-1267, 2014
  1109. Predictive value of the IFNL4 polymorphism on outcome of telaprevir, peginterferon, and ribavirin therapy for older patients with genotype 1b chronic hepatitis C, JOURNAL OF GASTROENTEROLOGY, 49(12), 1548-1556, 2014
  1110. Quantitative Effect of Natural Killer-Cell Licensing on Hepatocellular Carcinoma Recurrence after Curative Hepatectomy, CANCER IMMUNOLOGY RESEARCH, 2(12), 1142-1147, 2014
  1111. Non-invasive assessment of liver steatosis in non-alcoholic fatty liver disease, HEPATOLOGY RESEARCH, 44(14), E420-E427, 2014
  1112. Interferon lambda 4 polymorphism affects on outcome of telaprevir, pegylated interferon and ribavirin combination therapy for chronic hepatitis C, HEPATOLOGY RESEARCH, 44(14), E447-E454, 2014
  1113. Hepatitis C Virus (HCV) Reactivation Caused by Steroid Therapy for Dermatomyositis, INTERNAL MEDICINE, 53(23), 2689-2693, 2014
  1114. Differences in K-ras and mitochondrial DNA mutations and microsatellite instability between colorectal cancers of Vietnamese and Japanese patients, BMC GASTROENTEROLOGY, 14, 2014
  1115. Ratio of Serum Levels of AGEs to Soluble Form of RAGE Is a Predictor of Endothelial Function, DIABETES CARE, 38(1), 119-125, 2015
  1116. Major predictors of portal hypertensive enteropathy in patients with liver cirrhosis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(1), 124-130, 2015
  1117. Integrated Analysis of Whole Genome and Transcriptome Sequencing Reveals Diverse Transcriptomic Aberrations Driven by Somatic Genomic Changes in Liver Cancers, PLOS ONE, 9(12), 2014
  1118. A Computer System To Be Used With Laser-based Endoscopy for Quantitative Diagnosis of Early Gastric Cancer, JOURNAL OF CLINICAL GASTROENTEROLOGY, 49(2), 108-115, 2015
  1119. Towards safer and appropriate application of endoscopic submucosal dissection for T1 colorectal carcinoma as total excisional biopsy: Future perspectives, DIGESTIVE ENDOSCOPY, 27(2), 216-222, 2015
  1120. mTOR and PDGF Pathway Blockade Inhibits Liver Metastasis of Colorectal Cancer by Modulating the Tumor Microenvironment, AMERICAN JOURNAL OF PATHOLOGY, 185(2), 399-408, 2015
  1121. Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection, EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 9(1), 21-30, 2015
  1122. Effect of prolonged administration of pegylated interferon/ribavirin therapy in genotypes 2a and 2b: Propensity score-matched analysis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(2), 337-344, 2015
  1123. Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity, Nature Communications, 6, 2015
  1124. Endoscopic Submucosal Dissection as Total Excisional Biopsy for Clinical T1 Colorectal Carcinoma, DIGESTION, 91(1), 64-69, 2015
  1125. Differences in serum microRNA profiles in hepatitis B and C virus infection, JOURNAL OF INFECTION, 70(3), 273-287, 2015
  1126. Combining molecular targeted drugs to inhibit both cancer cells and activated stromal cells in colon cancer, CANCER RESEARCH, 74(19), 2014
  1127. Interaction between bone marrow-derived mesenchymal stem cells and tumor cells induces expression of fibronectin in human colon cancer cells, CANCER RESEARCH, 74(19), 2014
  1128. The effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(3), 619-627, 2015
  1129. Emerging treatments for chronic hepatitis C, JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 114(3), 204-215, 2015
  1130. Rate of Unintended Helicobacter pylori Eradication in the Vietnamese, HELICOBACTER, 20(2), 156-157, 2015
  1131. Evaluation of early response to hepatic arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma using the combination of Response Evaluation Criteria in Solid Tumors and tumor markers, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(4), 726-732, 2015
  1132. Risk factors and management of positive horizontal margin in early gastric cancer resected by en bloc endoscopic submucosal dissection, GASTRIC CANCER, 18(2), 332-338, 2015
  1133. Evaluation of Antibiotic Use to Prevent Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Cholangitis, HEPATO-GASTROENTEROLOGY, 62(138), 417-424, 2015
  1134. Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection, SCIENCE TRANSLATIONAL MEDICINE, 7(282), 2015
  1135. Stereotactic body radiotherapy for patients with small hepatocellular carcinoma ineligible for resection or ablation therapies, HEPATOLOGY RESEARCH, 45(4), 378-386, 2015
  1136. Randomized Trial of Interferon- and Ribavirin-Free Ombitasvir/Paritaprevir/Ritonavir in Treatment-Experienced Hepatitis C Virus-Infected Patients, HEPATOLOGY, 61(5), 1523-1532, 2015
  1137. Eicosapentaenoic acid/arachidonic acid ratio as a possible link between non-alcoholic fatty liver disease and cardiovascular disease, HEPATOLOGY RESEARCH, 45(5), 533-539, 2015
  1138. Novel Robust in Vitro Hepatitis B Virus Infection Model Using Fresh Human Hepatocytes Isolated from Humanized Mice, AMERICAN JOURNAL OF PATHOLOGY, 185(5), 1275-1285, 2015
  1139. Role of 3-D conformal radiotherapy for major portal vein tumor thrombosis combined with hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma, HEPATOLOGY RESEARCH, 45(6), 607-617, 2015
  1140. Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis, HEPATOLOGY RESEARCH, 45(6), 656-662, 2015
  1141. Disseminated carcinomatosis of the bone marrow originating from hepatocellular carcinoma. A case report, HEPATOLOGY RESEARCH, 45(6), 705-710, 2015
  1142. The Time Course of Dynamic Computed Tomographic Appearance of Radiation Injury to the Cirrhotic Liver Following Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma, PLOS ONE, 10(6), 2015
  1143. Rapid, Sensitive, and Accurate Evaluation of Drug Resistant Mutant (NS5A-Y93H) Strain Frequency in Genotype 1b HCV by Invader Assay, PLOS ONE, 10(6), 2015
  1144. ADIPOQ polymorphisms are associated with insulin resistance in Japanese women, ENDOCRINE JOURNAL, 62(6), 513-521, 2015
  1145. Efficacy of radiofrequency ablation for initial recurrent hepatocellular carcinoma after curative treatment: Comparison with primary cases, EUROPEAN JOURNAL OF RADIOLOGY, 84(8), 1540-1545, 2015
  1146. IL-1 beta/ATF3-mediated induction of Ski2 expression enhances hepatitis B virus x mRNA degradation, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 503(3), 1854-1860, 20180910
  1147. Chromosome 4q25 Variant rs6817105 Bring Sinus Node Dysfunction and Left Atrial Enlargement, SCIENTIFIC REPORTS, 8, 20181001
  1148. Chromosomal Abnormalities in Human Lymphocytes after Computed Tomography Scan Procedure, RADIATION RESEARCH, 190(4), 424-432, 201810
  1149. Comparison of Stereotactic Body Radiation Therapy Combined With or Without Transcatheter Arterial Chemoembolization for Patients With Small Hepatocellular Carcinoma Ineligible for Resection or Ablation Therapies, TECHNOLOGY IN CANCER RESEARCH & TREATMENT, 17, 20180701
  1150. HCN4 Gene Polymorphisms Are Associated With Occurrence of Tachycardia-Induced Cardiomyopathy in Patients With Atrial Fibrillation, CIRCULATION-GENOMIC AND PRECISION MEDICINE, 11(7), 201807
  1151. Advanced liver fibrosis effects on the response to sofosbuvir-based antiviral therapies for chronic hepatitis C, JOURNAL OF MEDICAL VIROLOGY, 90(12), 1834-1840, 201812
  1152. The novel cutoff points for the FIB4 index categorized by age increase the diagnostic accuracy in NAFLD: a multi-center study, JOURNAL OF GASTROENTEROLOGY, 53(11), 1216-1224, 201811
  1153. Molecular Mechanisms of Hepatocarcinogenesis Following Sustained Virological Response in Patients with Chronic Hepatitis C Virus Infection, VIRUSES-BASEL, 10(10), 201810
  1154. Early experience of seven hepatocellular carcinoma cases treated with regorafenib, CLINICAL CASE REPORTS, 6(11), 2217-2223, 201811
  1155. Diagnosis of superficial esophageal squamous cell carcinoma invasion depth before endoscopic submucosal dissection, DISEASES OF THE ESOPHAGUS, 31(7), 201807
  1156. Magnifying Endoscopy with Narrow Band Imaging in Estimating the Invasion Depth of Superficial Esophageal Squamous Cell Carcinomas, DIGESTION, 98(4), 249-256, 2018
  1157. CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic hepatitis B patients, JOURNAL OF VIRAL HEPATITIS, 25(12), 1555-1564, 201812
  1158. Endothelial Dysfunction, Increased Arterial Stiffness, and Cardiovascular Risk Prediction in Patients With Coronary Artery Disease: FMD-J (Flow-Mediated Dilation Japan) Study A, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 7(14), 20180717
  1159. Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes, VIROLOGY, 525, 48-61, 201812
  1160. Range of Normal Liver Stiffness and Factors Associated With Increased Stiffness Measurements in Apparently Healthy Individuals, CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 17(1), 54-+, 201901
  1161. Comparison of hepatic arterial infusion chemotherapy between 5-fluorouracil-based continuous infusion chemotherapy and low-dose cisplatin monotherapy for advanced hepatocellular carcinoma, HEPATOLOGY RESEARCH, 48(13), 1118-1130, 201812
  1162. Cross-over study in hyperammonemia patients for efficacy, safety, and acceptability of a new lactulose preparation (SK-1202) compared to approved drug, HEPATOLOGY RESEARCH, 48(13), 1178-1183, 201812
  1163. The association between serum cytokine and chemokine levels and antiviral response by entecavir treatment in chronic hepatitis B patients, ANTIVIRAL THERAPY, 23(3), 239-248, 2018
  1164. Dual Red Imaging Maintains Clear Visibility During Colorectal Endoscopic Submucosal Dissection, DIGESTIVE DISEASES AND SCIENCES, 64(1), 224-231, 201901
  1165. Efficacy and safety of sofosbuvir-velpatasvir with or without ribavirin in HCV-infected Japanese patients with decompensated cirrhosis: an open-label phase 3 trial, JOURNAL OF GASTROENTEROLOGY, 54(1), 87-95, 201901
  1166. Gastric Cancer with Submucosal Invasion after Successful Helicobacter pylori Eradication: A Propensity Score-Matched Analysis of Patients with Annual Patient Endoscopic Survey, DIGESTION, 99(1), 59-65, 2019
  1167. The utility of a novel colonoscope with retroflexion for colorectal endoscopic submucosal dissection, ENDOSCOPY INTERNATIONAL OPEN, 7(2), E130-E137, 201902
  1168. The impact of interferon-free direct-acting antivirals on clinical outcome after curative treatment for hepatitis C virus-associated hepatocellular carcinoma: Comparison with interferon-based therapy, JOURNAL OF MEDICAL VIROLOGY, 91(4), 650-658, 201904
  1169. Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor, PLOS ONE, 14(2), 20190219
  1170. Early-stage serrated adenocarcinomas are divided into several molecularly distinct subtypes, PLOS ONE, 14(2), 20190220
  1171. Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures, JOURNAL OF GASTROENTEROLOGY, 54(3), 291-296, 201903
  1172. Levocarnitine Use Is Associated With Improvement in Sarcopenia in Patients With Liver Cirrhosis, HEPATOLOGY COMMUNICATIONS, 3(3), 348-355, 201903
  1173. Rectal Lymphoid Follicle Aphthous Lesions Frequently Progress to Ulcerative Colitis with Proximal Extension, INTERNAL MEDICINE, 58(5), 625-631, 201903
  1174. Ser96Ala genetic variant of the human histidine-rich calcium-binding protein is a genetic predictor of recurrence after catheter ablation in patients with paroxysmal atrial fibrillation, PLOS ONE, 14(3), 20190306
  1175. Epidemiological survey of hemoglobin A1c and liver fibrosis in a general population with non-alcoholic fatty liver disease, HEPATOLOGY RESEARCH, 49(3), 296-303, 201903
  1176. Construction of a risk model for the development of metachronous squamous cell carcinoma after endoscopic resection of esopahageal squamous cell carcinoma, ESOPHAGUS, 16(2), 141-146, 201904
  1177. A nationwide survey on non-B, non-C hepatocellular carcinoma in Japan: 2011-2015 update, JOURNAL OF GASTROENTEROLOGY, 54(4), 367-376, 201904
  1178. Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: a pilot study, ANTIVIRAL THERAPY, 23(8), 639-646, 2018
  1179. Long-term prognosis after treatment for T1 carcinoma of laterally spreading tumors: a multicenter retrospective study, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 34(3), 481-490, 201903
  1180. Early Multiphasic HBV Infection Initiation Kinetics Is Not Clone-Specific and Is Not Affected by Hepatitis D Virus (HDV) Infection, VIRUSES-BASEL, 11(3), 20190315
  1181. Coffee with a high content of chlorogenic acids and low content of hydroxyhydroquinone improves postprandial endothelial dysfunction in patients with borderline and stage 1 hypertension, EUROPEAN JOURNAL OF NUTRITION, 58(3), 989-996, 201904
  1182. Rapid and persistent decline in soluble CD163 with successful direct-acting antiviral therapy and associations with chronic hepatitis C histology, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 53(8), 986-993, 2018
  1183. Target of Triglycerides as Residual Risk for Cardiovascular Events in Patients With Coronary Artery Disease - Post Hoc Analysis of the FMD-J Study A, CIRCULATION JOURNAL, 83(5), 1064-+, 201905
  1184. The Clinical Usefulness of the PillCam Progress Indicator for Route Selection in Double Balloon Endoscopy, INTERNAL MEDICINE, 58(10), 1375-1381, 2019
  1185. HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response, GASTROENTEROLOGY, 156(8), 2313-+, 201906
  1186. Alpha-fetoprotein and des-gamma-carboxy-prothrombin at twenty-four weeks after interferon-based therapy predict hepatocellular carcinoma development, WORLD JOURNAL OF HEPATOLOGY, 7(27), 2757-2764, 20151128
  1187. Circulating Tumor DNA Analysis for Liver Cancers and Its Usefulness as a Liquid Biopsy, CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 1(5), 516-534, 201509
  1188. Use of Mac-2 Binding Protein as a Biomarker for Nonalcoholic Fatty Liver Disease Diagnosis, HEPATOLOGY COMMUNICATIONS, 1(8), 780-791, 201710
  1189. Experience with Balloon Dilatation in Crohn's and Non-Crohn's Benign Small-Bowel Strictures: Is There a Difference?, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2019
  1190. Impact of sclerosing dacryoadenitis/sialadenitis on relapse during steroid therapy in patients with type 1 autoimmune pancreatitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 54(2), 259-264, 20190201
  1191. Impact of controlled attenuation parameter on detecting fibrosis using liver stiffness measurement, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 47(7), 989-1000, 201804
  1192. Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes, CANCER CELL, 35(6), 932-+, 20190610
  1193. Regulation of the Hepatitis B virus replication and gene expression by the multi-functional protein TARDBP, SCIENTIFIC REPORTS, 9, 20190611
  1194. Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis, JOURNAL OF BIOMEDICAL SCIENCE, 26, 20190606
  1195. Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice, JOURNAL OF GASTROENTEROLOGY, 54(7), 650-659, 201907
  1196. Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study, JOURNAL OF HYPERTENSION, 37(5), 1083-1095, 201905
  1197. Effect of Saxagliptin on Endothelial Function in Patients with Type 2 Diabetes: A Prospective Multicenter Study, SCIENTIFIC REPORTS, 9, 20190715
  1198. Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice, JOURNAL OF GENERAL VIROLOGY, 100(7), 1123-1131, 201907
  1199. Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of Hepatitis C Virus-Infected Cells and Liver to Identify Pathways Associated With Disease Development, GASTROENTEROLOGY, 157(2), 537-+, 201908
  1200. Real-world virological efficacy and safety of daclatasvir/asunaprevir/beclabuvir in patients with chronic hepatitis C virus genotype 1 infection in Japan, JOURNAL OF GASTROENTEROLOGY, 54(8), 742-751, 201908
  1201. y Integrated analysis of 8-week glecaprevir/pibrentasvir in Japanese and overseas patients without cirrhosis and with hepatitis C virus genotype 1 or 2 infection, JOURNAL OF GASTROENTEROLOGY, 54(8), 752-761, 201908
  1202. Can surveillance colonoscopy be discontinued in an elderly population with diminutive polyps?, JOURNAL OF THE ANUS RECTUM AND COLON, 3(3), 128-135, 201907
  1203. Helicobacter suis infection is associated with nodular gastritis-like appearance of gastric mucosa-associated lymphoid tissue lymphoma, CANCER MEDICINE, 8(9), 4370-4379, 201908
  1204. Relationship between home blood pressure and vascular function in patients receiving antihypertensive drug treatment, HYPERTENSION RESEARCH, 42(8), 1175-1185, 201908
  1205. Percutaneous transvenous shunt occlusion for portosystemic encephalopathy due to lenvatinib administration to a patient with hepatocellular carcinoma and portosystemic shunt, CLINICAL JOURNAL OF GASTROENTEROLOGY, 12(4), 341-346, 201908
  1206. Correlation between Early Tumor Marker Response and Imaging Response in Patients with Advanced Hepatocellular Carcinoma Treated with Lenvatinib, ONCOLOGY, 97(2), 75-81, 2019
  1207. Management of HCV patients in cases of direct-acting antiviral failure, EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 13(9), 839-848, 20190902
  1208. Early changes in ammonia levels and liver function in patients with advanced hepatocellular carcinoma treated by lenvatinib therapy, SCIENTIFIC REPORTS, 9, 20190820
  1209. Alcohol Use Disorders Identification Test-consumption Predicts the Risk of Excessive Alcohol Consumption After Liver Transplantation, TRANSPLANTATION PROCEEDINGS, 51(6), 1934-1938, 2019
  1210. HOMA-IR: An independent predictor of advanced liver fibrosis in nondiabetic non-alcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 34(8), 1390-1395, 201908
  1211. Preceding endoscopic submucosal dissection for T1 colorectal carcinoma does not affect the prognosis of patients who underwent additional surgery: a large multicenter propensity score-matched analysis, JOURNAL OF GASTROENTEROLOGY, 54(10), 897-906, 201910
  1212. Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy, JOURNAL OF GASTROENTEROLOGY, 54(10), 907-915, 201910
  1213. Clinical features of hepatocellular carcinoma in nonalcoholic fatty liver disease patients without advanced fibrosis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 34(9), 1626-1632, 201909
  1214. Relationships Between Calcium Channel Blockers and Vascular Function Tests, AMERICAN JOURNAL OF HYPERTENSION, 32(7), 640-648, 201907
  1215. Effects of the Dipeptidyl Peptidase 4 Inhibitor Alogliptin on Blood Pressure in Hypertensive Patients with Type 2 Diabetes Mellitus, AMERICAN JOURNAL OF HYPERTENSION, 32(7), 695-702, 201907
  1216. Association of extremely high levels of high-density lipoprotein cholesterol with endothelial dysfunction in men, JOURNAL OF CLINICAL LIPIDOLOGY, 13(4), 664-672, 201908
  1217. eVIDENCE: a practical variant filtering for low-frequency variants detection in cell-free DNA, SCIENTIFIC REPORTS, 9, 20191022
  1218. Pruritus in patients with chronic liver disease and serum autotaxin levels in patients with primary biliary cholangitis, BMC GASTROENTEROLOGY, 19(1), 20191024
  1219. Potential of Helicobacter pylori-uninfected signet ring cell carcinoma to invade the submucosal layer, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 34(11), 1955-1962, 201911
  1220. Clinical Utility of Emergency Capsule Endoscopy for Diagnosing the Source and Nature of Ongoing Overt Obscure Gastrointestinal Bleeding, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2019, 20191201
  1221. Investigation of Fluorodeoxyglucose Positron Emission Tomography for the Diagnosis of Solid Pseudopapillary Neoplasm of the Pancreas A Study Associated With a National Survey of Solid Pseudopapillary Neoplasms, PANCREAS, 48(10), 1312-1320, 2019
  1222. Regression of Idiopathic Thrombocytopenic Purpura in a Patient With Eradication of Hepatitis C Virus by Direct-Acting Antivirals, HEPATOLOGY, 71(1), 389-391, 202001
  1223. Clinical Usefulness of Dual Red Imaging in Gastric Endoscopic Submucosal Dissection: A Pilot Study, CLINICAL ENDOSCOPY, 53(1), 54-59, 202001
  1224. A Cost-Effectiveness Analysis of Glecaprevir/Pibrentasvir Versus Existing Direct-Acting Antivirals to Treat Chronic Hepatitis C in Japan, ADVANCES IN THERAPY, 37(1), 457-476, 202001
  1225. Management of refractory ascites attenuates muscle mass reduction and improves survival in patients with decompensated cirrhosis, JOURNAL OF GASTROENTEROLOGY, 55(2), 217-226, 202002
  1226. Preoperative PET-CT is useful for predicting recurrent extrahepatic metastasis of hepatocellular carcinoma after resection, EUROPEAN JOURNAL OF RADIOLOGY, 124, 202003
  1227. A case of primary malignant melanoma of the esophagus with a widely expanded surface area, CLINICAL JOURNAL OF GASTROENTEROLOGY, 12(5), 424-428, 201910
  1228. Diagnostic Criteria of Flow-Mediated Vasodilation for Normal Endothelial Function and Nitroglycerin-Induced Vasodilation for Normal Vascular Smooth Muscle Function of the Brachial Artery, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 9(2), 20200121
  1229. Clinical outcomes of endoscopic resection for superficial non-ampullary duodenal tumors, ENDOSCOPY INTERNATIONAL OPEN, 8(3), E354-E359, 202003
  1230. Clinical usefulness of the S-O clip during colorectal endoscopic submucosal dissection in difficult-to-access submucosal layer, ENDOSCOPY INTERNATIONAL OPEN, 8(3), E437-E444, 202003
  1231. Successful retreatment with 12 weeks of glecaprevir and pibrentasvir for a genotype 2a HCV-infected hemodialysis patient who failed to respond to 8 weeks of prior glecaprevir and pibrentasvir therapy, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(2), 267-270, 202004
  1232. The Evaluation of Esophageal Motility Using Infusion Manometry with a Trans-nasal Endoscope: A Preliminary Study, INTERNAL MEDICINE, 59(7), 887-890, 2020
  1233. Three Children Treated with Direct-acting Antivirals for Chronic Hepatitis C Virus Genotype 1b Infection, INTERNAL MEDICINE, 59(7), 941-944, 2020
  1234. Serum amyloid A is a better predictive biomarker of mucosal healing than C-reactive protein in ulcerative colitis in clinical remission, BMC GASTROENTEROLOGY, 20(1), 20200403
  1235. Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations, EBIOMEDICINE, 53, 202003
  1236. Genomic Characterization of Non-Invasive Differentiated-Type Gastric Cancer in the Japanese Population, CANCERS, 12(2), 202002
  1237. Sinusoidal obstruction syndrome post-treatment with trastuzumab emtansine (T-DM1) in advanced breast cancer, INTERNATIONAL CANCER CONFERENCE JOURNAL, 9(1), 18-23, 202001
  1238. Comparative study on the replication of HCV1b genome between wild-type and cell culture-adaptive mutant in regard to sensitivities against anti-HCV drugs, MICROBIOLOGY AND IMMUNOLOGY, 64(4), 296-303, 202004
  1239. Skeletal Muscle Loss during Tyrosine Kinase Inhibitor Treatment for Advanced Hepatocellular Carcinoma Patients, LIVER CANCER, 9(2), 148-155, 202004
  1240. Predicting atrial fibrillation using a combination of genetic risk score and clinical risk factors, HEART RHYTHM, 17(5), 699-705, 202005
  1241. Pan-cancer analysis of whole genomes, NATURE, 578(7793), 82-+, 20200206
  1242. Population Pharmacokinetics of Glecaprevir/Pibrentasvir in HCV-infected Japanese Subjects in Phase 3 CERTAIN-1 and CERTAIN-2 Trials, JOURNAL OF CLINICAL PHARMACOLOGY, 60(3), 331-339, 202003
  1243. Isolated cardiac metastases of hepatocellular carcinoma after resection: a case report, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(3), 421-427, 202006
  1244. JNJ-4178 (adafosbuvir, odalasvir, and simeprevir) in Japanese patients with chronic hepatitis C virus genotype 1 or 2 infection with or without compensated cirrhosis: the Phase IIa OMEGA-3 study, JOURNAL OF GASTROENTEROLOGY, 55(6), 640-652, 202006
  1245. Serum miR-379 expression is related to the development and progression of hypercholesterolemia in non-alcoholic fatty liver disease, PLOS ONE, 15(2), 20200227
  1246. Diagnostic Yield of Colon Capsule Endoscopy in Detection of Superficial Colorectal Lesions, DIGESTION, 101(3), 262-269, 202005
  1247. Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib, THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 12, 202005
  1248. Discordant pathological diagnosis of non-alcoholic fatty liver disease: A prospective multicenter study, JGH OPEN, 4(3), 497-502, 202006
  1249. Impact of the introduction of direct-acting anti-viral drugs on hepatocarcinogenesis: a prospective serial follow-up MRI study, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 52(2), 359-370, 202007
  1250. Efficacy of a self-management program in patients with chronic viral hepatitis in China, BMC NURSING, 18(1), 20190918
  1251. Renal metastasis from primary hepatocellular carcinoma: a case report, INTERNATIONAL CANCER CONFERENCE JOURNAL, 9(3), 141-145, 202007
  1252. Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases, NATURE GENETICS, 52(7), 669-+, 202007
  1253. Diminished hepatic IFN response following HCV clearance triggers HBV reactivation in coinfection, JOURNAL OF CLINICAL INVESTIGATION, 130(6), 3205-3220, 20200601
  1254. Incidence of microsatellite instability-high hepatocellular carcinoma among Japanese patients and response to pembrolizumab, HEPATOLOGY RESEARCH, 50(7), 885-888, 202007
  1255. Increased arterial stiffness and cardiovascular risk prediction in controlled hypertensive patients with coronary artery disease: post hoc analysis of FMD-J (Flow-mediated Dilation Japan) Study A, HYPERTENSION RESEARCH, 43(8), 781-790, 202008
  1256. Hematocrit, hemoglobin and red blood cells are associated with vascular function and vascular structure in men, SCIENTIFIC REPORTS, 10(1), 20200710
  1257. Risk factors for histological progression of non-alcoholic steatohepatitis analyzed from repeated biopsy cases, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 35(8), 1412-1419, 202008
  1258. Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma, CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 11, 202005
  1259. Vascular function is further impaired in subjects aged 80 years or older, HYPERTENSION RESEARCH, 43(9), 914-921, 202009
  1260. Clinical and genomic characteristics of mucosal signet-ring cell carcinoma in Helicobacter pylori-uninfected stomach, BMC GASTROENTEROLOGY, 20(1), 20200729
  1261. Modifying Effect of Chronic Atrophic Gastritis on Radiation Risk for Noncardia Gastric Cancer According to Histological Type, RADIATION RESEARCH, 194(2), 180-187, 202008
  1262. Metabolomic/lipidomic-based analysis of plasma to diagnose hepatocellular ballooning in patients with non-alcoholic fatty liver disease: A multicenter study, HEPATOLOGY RESEARCH, 50(8), 955-965, 202008
  1263. PD1 gene polymorphism is associated with a poor prognosis in hepatocellular carcinoma following liver resection, cohort study, INTERNATIONAL JOURNAL OF SURGERY, 80, 84-90, 202008
  1264. Relationship between high-density lipoprotein cholesterol levels and endothelial function in women: a cross-sectional study, BMJ OPEN, 10(7), 2020
  1265. Treatment outcomes after splenectomy with gastric devascularization or balloon-occluded retrograde transvenous obliteration for gastric varices: a propensity score-weighted analysis from a single institution, JOURNAL OF GASTROENTEROLOGY, 55(9), 877-887, 202009
  1266. Japan Society of Hepatology Guidelines for the Management of Hepatitis B Virus Infection: 2019 update, HEPATOLOGY RESEARCH, 50(8), 892-923, 202008
  1267. Real-world learning curve analysis of colorectal endoscopic submucosal dissection: a large multicenter study, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 34(8), 3344-3351, 202008
  1268. A case of advanced HCC treated with lenvatinib after hepatic arterial infusion chemotherapy combined with radiation therapy treatment for portal vein tumor thrombosis in the main trunk, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(5), 839-843, 202010
  1269. Culture density contributes to hepatic functions of fresh human hepatocytes isolated from chimeric mice with humanized livers: Novel, long-term, functional two-dimensionalin vitrotool for developing new drugs, PLOS ONE, 15(9), 20200911
  1270. Hepatic Arterial Infusion Chemotherapy versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma, LIVER CANCER, 9(5), 583-595, 202009
  1271. Complete response to pembrolizumab in advanced hepatocellular carcinoma with microsatellite instability, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(5), 867-872, 202010
  1272. Detection of acute toxicity of aflatoxin B1 to human hepatocytesin vitroandin vivousing chimeric mice with humanized livers, PLOS ONE, 15(9), 20200923
  1273. Trends in Hepatic Functional Reserve of Patients with Hepatocellular Carcinoma Treated with Tyrosine Kinase Inhibitors, ONCOLOGY, 98(10), 727-733, 202010
  1274. Liver fibrosis assessments using FibroScan, virtual-touch tissue quantification, the FIB-4 index, and mac-2 binding protein glycosylation isomer levels compared with pathological findings of liver resection specimens in patients with hepatitis C infection, BMC GASTROENTEROLOGY, 20(1), 20200925
  1275. Modeling-Based Response-Guided Glecaprevir-Pibrentasvir Therapy for Chronic Hepatitis C to Identify Patients for Ultrashort Treatment Duration, JOURNAL OF INFECTIOUS DISEASES, 222(7), 1165-1169, 20201001
  1276. Pre-impaired fasting glucose state is a risk factor for endothelial dysfunction: Flow-mediated Dilation Japan (FMD-J) study, BMJ OPEN DIABETES RESEARCH & CARE, 8(1), 2020
  1277. Analysis of Post-Progression Survival in Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib, ONCOLOGY, 98(11), 787-797, 202011
  1278. Impact of viral eradication by direct-acting antivirals on the risk of hepatocellular carcinoma development, prognosis, and portal hypertension in hepatitis C virus-related compensated cirrhosis patients, HEPATOLOGY RESEARCH, 50(11), 1222-1233, 202011
  1279. Decrease in fasting insulin secretory function correlates with significant liver fibrosis in Japanese non-alcoholic fatty liver disease patients, JGH OPEN, 4(5), 929-936, 202010
  1280. Fluoxazolevir inhibits hepatitis C virus infection in humanized chimeric mice by blocking viral membrane fusion, NATURE MICROBIOLOGY, 5(12), 1532-+, 202012
  1281. Pilot study of tenofovir disoproxil fumarate and pegylated interferon-alpha 2a add-on therapy in Japanese patients with chronic hepatitis B, JOURNAL OF GASTROENTEROLOGY, 55(10), 977-989, 202010
  1282. Real-word efficacy of sofosbuvir, velpatasvir plus ribavirin therapy for chronic hepatitis patients who failed to prior DAA therapy with NS5A-P32 deletion mutated HCV infection, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(6), 1233-1238, 202012
  1283. A Comparison of Adrenalectomy and Eplerenone on Vascular Function in Patients with Aldosterone-producing Adenoma, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 105(11), 202011
  1284. Real-world efficacy of sofosbuvir plus velpatasvir therapy for patients with hepatitis C virus-related decompensated cirrhosis, HEPATOLOGY RESEARCH, 50(11), 1234-1243, 202011
  1285. PNPLA3andHLA-DQB1polymorphisms are associated with hepatocellular carcinoma after hepatitis C virus eradication, JOURNAL OF GASTROENTEROLOGY, 55(12), 1162-1170, 202012
  1286. Stromal reaction inhibitor and immune-checkpoint inhibitor combination therapy attenuates excluded-type colorectal cancer in a mouse model, CANCER LETTERS, 498, 111-120, 20210201
  1287. Low Levels of Low-Density Lipoprotein Cholesterol and Endothelial Function in Subjects without Lipid-Lowering Therapy, JOURNAL OF CLINICAL MEDICINE, 9(12), 202012
  1288. Clinical significance of endoscopic ultrasonography in diagnosing invasion depth of early gastric cancer prior to endoscopic submucosal dissection, GASTRIC CANCER, 24(1), 145-155, 202101
  1289. Usefulness of linked color imaging in the early detection of superficial esophageal squamous cell carcinomas, ESOPHAGUS, 18(1), 118-124, 202101
  1290. Eradication of hepatitis C virus with direct-acting antivirals improves glycemic control in diabetes: A multicenter study., JGH open : an open access journal of gastroenterology and hepatology, 5(2), 118-234, 20210201
  1291. A case with life-threatening secondary sclerosing cholangitis caused by nivolumab., Clinical journal of gastroenterology, 14(1), 283-287, 20210201
  1292. Abatacept treatment for patients with severe acute hepatitis caused by hepatitis B virus infection-Pilot study., Journal of viral hepatitis, 28(2), 400-409, 20210201
  1293. Association of Body Mass Index with Endothelial Function in Asian Men., International journal of cardiology, 324, 186-192, 20210201
  1294. Role of Endoscopic Ultrasonography and Endoscopic Retrograde Cholangiopancreatography in the Diagnosis of Pancreatic Cancer., Diagnostics (Basel, Switzerland), 11(2), 20210204
  1295. Type IV Collagen 7S Is the Most Accurate Test For Identifying Advanced Fibrosis in NAFLD With Type 2 Diabetes., Hepatology communications, 5(4), 559-572, 20210401
  1296. Clinical usefulness of combination therapy with polidocanol injection and argon plasma coagulation for gastric antral vascular ectasia., JGH open : an open access journal of gastroenterology and hepatology, 5(4), 465-469, 20210401

Publications such as books

  1. 2006, Molecular pathologic application as a predictor of lymph node metastasis in submucosal colorectal carcinoma:implication of immunohistochemical alterations at the deepest invasive margin , 2006, 04, Scholarly Book, Joint work, 171
  2. 2005, Role of invariant natural killer T cells in the regulation of the inflammatory response in experimental colitis in mice , 2005, 12, Scholarly Book, Joint work, 35
  3. 1998, Methods in molecular medicine-hepatitis C protocols. Genotyping hepatitis C virus by type-specific primers for PCR based on NS5 region. , Humana Press, 1998
  4. 1998, Hepatitis C protocols; Genotyping hepatitis C virus by type-specific primers or PCR based on NS5 region , Humana Press, 1998, Scholarly Book, Single work
  5. 1994, Viral hepatitis and liver disease. High virus titer, slow virus decrease, genotype(]G0002[), and sequence variability of E2/NS1 HVR predict poor response to interferon therapy in chronic hepatitis C. , Springer Verlag, 1994
  6. 1994, High virus titer, slow virus decrease, genotypeII, and sequence variability of E2/NS1 HVR predict poor response to interferon therapy in chronic hepatitis C Viral hepatitis and liver disease , Springer Verlag, 1994
  7. 2017, Hepatotos C Virus Treatment, Highly Effective Therapy with Direct Acting Antivirals and Associated Viral Resistance, Springer, 2017, Scholarly Book, Compilation
  8. 2017/09/05, Hepatitis B Virus and Liver Desease, Unmet Needs in Basic Research: In Vitro and In Vivo Models, Springer Nature Singapore Pre Ltd., 2018, 2018, Scholarly Book, Cocompilation, Kazuaki Chayama, Nelson Hayes.
  9. 2017/09/30, Management for DAA resistant-associated variants, Management for DAA resistant-associated variants, 2017, 9月
  10. 2017/12, The Liver Cancer Journal, Meeting Report
  11. 2018, Clinics in Gastroenterology, 2018, Book(general), Supervisor

Invited Lecture, Oral Presentation, Poster Presentation

  1. chronic hepatitis virus infection and interferon, 2017/10/30, Without Invitation, Japanese
  2. Baselin RAS Test: Clinical practice, The Liver Week 2017, 2017/06/23, With Invitation, Japanese, Korea
  3. Efficacy and safety of Glecaprevir/Pibrentasvir in Japanese Patients with Chronic GT1 Hepatitis C Virus Infection with and without Cirrhosis, 2017/06/09, Without Invitation, English, Hiroshima city
  4. Recent Progress in Treatment for Chronic Hepatitis C for Genotype 1, Asian Pacific Association for the Study of the Liver Single Topic Conference(APASL STC), 2017/04/11, Without Invitation, English, Nagasaki city
  5. Targeting Host and Viral Interactions: Insights from Mice Model, Asian Pacific Association for the Study of the Liver 2017(APASL 2017), 2017/02/17, With Invitation, English, Shanghai
  6. Recent Progress in Treatment for Chronic Hepatitis C, APDW2016, 2016/11/05, Without Invitation, English
  7. Practical Therapy of Chronic Hepatitis C, 2016/10/12, Without Invitation, English, Kyoto
  8. Integrated safety and Tolerability of DCV+ASV in Patients with Chronic HCV Genotype 1b Infection, 2016 APASL Single Topic Conference on Hepatitis C, 2016/06/12, Without Invitation, English, Kaohsiung (Taiwan)
  9. Best Strategy for Curing HCV Genotype 1 and 4: East vs. West, 2016 APASL Single Topic Conference on Hepatitis C, 2016/06/11, Without Invitation, Japanese, Kaohsiung city (Taiwan)
  10. A mouse model of human CTL mediated severe acute hepatitis B, 2016/05/20, Without Invitation, English, Makuhari
  11. HCV Treatiment Update-a New Era of All-oral HCV Treatment, The 46th Annual Meeting of GEST and The 25th Annual Meeting of DEST, 2016/03/26, With Invitation, English, Taipei
  12. GIFT-1:Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir in Elderly Japanese Patients, Asian Pacific Association for the Study of the Liver 2016(APASL 2016) (アジア太平洋肝臓病学会議), 2016/02/22, Without Invitation, Japanese, Tokyo
  13. Chimeric Animal Model, Asian Pacific Association for the Study of the Liver 2016(APASL 2016) (アジア太平洋肝臓病学会議), 2016/02/22, Without Invitation, Japanese, Tokyo
  14. DAA/PR therapy in Asian HCV patients, 2015/12/04, With Invitation, Japanese
  15. Circulating Tumor DNA Analysis for HCC., 2015/10/26, With Invitation, English
  16. Circulating Tumor DNA Analysis for HCC., 2015/10/26, Without Invitation, Japanese
  17. All Oral Direct Acting Antiviral Therapy for Chronic Hepatitis C, 2015/10/17, With Invitation, English
  18. Ombitasvir/Paritaprevir/Ritonavir for treatment of HCV genotype 1b in Japanese patients with or without Cirrhosis: results from GIFT-1, 2015/05/22, Without Invitation, English
  19. Hepatitis B mouse model involving CTL, 2015/04/23, Without Invitation, English, other
  20. All-oral Dual Combination of Daclatasvir plus Asunaprevir Compared with Telaprevir plus Peginterferon Alfa/Ribavirin in Treatment-maive Japanese Patients ChronicallyInfected with HCV Genotype 1b:Results from a Phase 3 Study, chayama kazuaki, 2014/11/11, Without Invitation
  21. Optimizing triple therapy, and IFN/RBV free regimens, chayama kazuaki, 2014/03/12, Without Invitation, Japanese
  22. Recent Progress in Treatment for Chronic Hepatitis C for Genotype 1, Asian Pacific Association for the Study of the Liver Single Topic Conference(APASL STC), Without Invitation, English, Nagasaki city
  23. Recent Progress in Treatment for Chronic Hepatitis C for Genotype 1, Asian Pacific Association for the Study of the Liver Single Topic Conference(APASL STC), Without Invitation, English, Nagasaki

Awards

  1. 1997/11, Award of The Japan Gastroenterological Endoscopy Society, The Japan Gastroenterological Endoscopy Society, The Superiority of Laparoscopic Examination in Predicting Hepatocellular Carcinoma after Interferon Therapy for Chronic
  2. 2008/01, GlaxoSmithKline Award

Patented

  1. Patent, JP5152745, 2012/12/14
  2. Patent
  3. Patent, JP2869759, 1999/01/08
  4. Patent, JP5656159, 2014/12/05
  5. Patent, JP5696317, 2015/02/20
  6. Patent, JP5888668, 2016/02/26
  7. Patent, JP5924644, 2016/04/28
  8. Patent
  9. Patent
  10. Patent
  11. Patent
  12. Patent
  13. Patent
  14. Patent
  15. Patent, 2014/12/05
  16. Patent
  17. Patent
  18. Patent
  19. Patent

Works, etc.

  1. 広島大学ラグビー部顧問,第32回中国四国医科学生ラグビーフットボール大会 広島大学優勝

External Funds

Acceptance Results of Competitive Funds

  1. 2021/04/01, 2023/03/31
  2. Research Program on Hepatitis, 2015/04/01, 2016/03/31
  3. Research Program on Hepatitis, 2015/04/01, 2016/03/31
  4. Health and Labour Sciences Research Grants, 2011, 2013
  5. Health and Labour Sciences Research Grants, 2012, 2016
  6. 2001
  7. 2003
  8. 2004
  9. 2004
  10. 2004
  11. 2006
  12. 2005
  13. 2007
  14. 2007
  15. 2008
  16. 2009
  17. 2009
  18. 2010
  19. 2010
  20. KAKENHI, 2014, 2014
  21. KAKENHI, Identification of SNPs on mature micro RNA to analyze origin of miRNA, 2013, 2013
  22. KAKENHI, Analysis of unknown pathogen using human hepatocyte chimeric mouseand massive parallel sequencing, 2012, 2012
  23. KAKENHI, Generation of a mouse model that shows specific features of human diseases., 2010, 2011
  24. KAKENHI, A comprehensive transcriptome analysis of humanized mouse liver using ultra high density cDNA micro array, 2009, 2011
  25. KAKENHI, 2007, 2007
  26. KAKENHI, Production of interferon stimulated gene library and screening of new therapeutic drug for hepatitis viruses, 2006, 2007
  27. KAKENHI, 2003, 2005
  28. KAKENHI, Specification of the factor in a liver cell required for multiplication of hepatitis C virus, 2001, 2003
  29. KAKENHI, Analysis of lamivudine resistance acquisition by hepatitis B virus., 2001, 2003
  30. KAKENHI, Detection of drug resistant mutant hepatitis B virus strain and its clinical application., 1998, 2000
  31. KAKENHI, Interferon resistance of hepatitis C virus, 1994, 1995
  32. Health and Labour Sciences Research Grants, 2014/04/01, 2015/03/31
  33. KAKENHI, 2015, 2016
  34. Research Program on Hepatitis , 2016/04/01, 2017/03/31
  35. Research Program on Hepatitis , 2016/04/01, 2017/03/31
  36. KAKENHI(Grant-in-Aid for Challenging Research (Pioneering)), 2017, 2019
  37. Research Program on Hepatitis , 2017/04/01, 2018/03/31
  38. Research Program on Hepatitis , 2017/04/01, 2018/03/31
  39. 2004/04/01
  40. 2017

Social Activities

Organizing Academic Conferences, etc.

  1. 2000/11
  2. 2001/10
  3. 2001/05
  4. 2001/10
  5. 2001/11
  6. 2001/02
  7. 2001/11
  8. 2001/02
  9. 2001/07
  10. 2001/07
  11. 2001/04
  12. 2001/05
  13. 2001/09
  14. 2001/12
  15. 2001/01
  16. 2009/09
  17. 2011/10
  18. 2012/02
  19. The 2nd Japan-Italy Liver Workshop, 2014/11, 2014/11
  20. The 11th JSH Single Topic Conference, 2014/11
  21. 2014/07
  22. 2016/11
  23. 2015/11, 2015/11
  24. 2017/06, 2017/06
  25. 2016/06, 2016/06
  26. 2017/07, 2017/07

Other Social Contributions

  1. Pancreatic Cancer Expert Meeting, 2017/05/26, 2017/05/26, Others
  2. Academic Workshop by Hiroshima University and Cairo University, Human hepatocyte chimeric mouse model for hepatitis virus studies, 2017/02/21, 2017/02/21