KAZUAKI CHAYAMA
Last Updated :2023/09/05
- Affiliations, Positions
- Graduate School of Biomedical and Health Sciences(Medical), Professor, Collaborative Research Laboratory
- Web Site
- E-mail
- chayama
hiroshima-u.ac.jp
- Self-introduction
- Since I became a Professor of the Faculty of Medicine, Hiroshima University, in September, 2000 and the head Professor of the Division of Gastroenterology of Hiroshima University Hospital in April 2002, our laboratory has evolved steadily as the result of the hard work of its doctors, staff and graduate students in the field of medical examination, education and research. We really appreciate the support of persons concerned with these activities.
Basic Information
Major Professional Backgrounds
- 1986/04/01, National Public Officers Mutual Aid Association Federation, Clinical Fellow
- 1981/05/01, Medical corporation Dojinkai, Clinical Fellow
- 1996/07/01, same, Medical director
- 2000/09/01, 2002/03/31, Hiroshima University, Faculty of Medicine, Professor
- 2002/04/01, 2019/03/31, Hiroshima University, Graduate School of Biomedical Sciences, Professor
- 2005/04/01, 2011/03/31, Hiroshima University, Hospital, Deputy Director
- 2009/04/01, 2011/03/31, Hiroshima University, Vice Executive
- 2011/04/01, 2015/03/31, Hiroshima University, Hospital, Director
- 2012/04/01, 2015/03/31, Hiroshima University, Executive and Vice President
- 2015/04/01, 2016/03/31, Hiroshima University, Special Assistant to the President
Educational Backgrounds
- Hiroshima University, Faculty of Medicine, Japan, 1974/04, 1981/03
Academic Degrees
- Doctor of Philosophy in Medical Sciences, The University of Tokyo
In Charge of Primary Major Programs
Research Fields
- Medicine,dentistry, and pharmacy;Clinical internal medicine;Gastroenterology
Research Keywords
- nucleotide sequence|Hepatitis-B
- epigenetics
- liver cirrhosis
- driver mutation
- deep sequence
- whole genome analysisi
- Hepatitis-C
- whole genome sequencing
- hepatitis
- hepatocellular carcinoma
Affiliated Academic Societies
- American Association for the Study of Liver Diseases
- Asia Pacific Association for the Study of the Liver
- International Association for the Study of the Liver
- The Japanese Society for Virology
- The Japanese Association for Metastasis Resarch
- The Japanese Society of Internal Medicine, 2000
- The Molecular Biology Society of Japan
- The japanese society of gastroenterology, 1998
- Japanese cancer association
- The japan diabetes society, 1982
- The japan society of hepatorogy, 2000
Research Activities
Academic Papers
- Untying relaxed circular DNA of hepatitis B virus by polymerase reaction provides a new option for accurate quantification and visualization of covalently closed circular DNA, JOURNAL OF GENERAL VIROLOGY, 103(2), 2022
- The importance of body composition assessment for patients with advanced hepatocellular carcinoma by bioelectrical impedance analysis in lenvatinib treatment, PLOS ONE, 17(1), 20220118
- Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease, SCIENCE TRANSLATIONAL MEDICINE, 14(650), 20220622
- White blood cell count is not associated with flow-mediated vasodilation or nitroglycerine-induced vasodilation, SCIENTIFIC REPORTS, 12(1), 20220517
- Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population, HUMAN MOLECULAR GENETICS, 26(3), 650-659, 20170201
- Quasispecies of Hepatitis C Virus Participate in Cell-Specific Infectivity, SCIENTIFIC REPORTS, 7, 20170322
- Long-term outcomes after endoscopic submucosal dissection for superficial colorectal tumors, GASTROINTESTINAL ENDOSCOPY, 85(3), 546-553, 201703
- Real-world efficacy and safety of daclatasvir and asunaprevir therapy for hepatitis C virus-infected cirrhosis patients, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 32(3), 645-650, 201703
- Endothelial dysfunction and abnormal vascular structure are simultaneously present in patients with heart failure with preserved ejection fraction, INTERNATIONAL JOURNAL OF CARDIOLOGY, 231, 181-187, 20170315
- Endothelial function is impaired in relation to alcohol intake even in the case of light alcohol consumption in Asian men; Flow-mediated Dilation Japan (FMD-J) Study, INTERNATIONAL JOURNAL OF CARDIOLOGY, 230, 523-528, 20170301
- IFNL4 polymorphism effects on outcome of simeprevir, peginterferon, and ribavirin therapy for older patients with genotype 1 chronic hepatitis C, HEPATOLOGY RESEARCH, 47(3), E5-E13, 201703
- Safety and efficacy of dual therapy with daclatasvir and asunaprevir for older patients with chronic hepatitis C, JOURNAL OF GASTROENTEROLOGY, 52(4), 504-511, 201704
- The combination of elbasvir and grazoprevir for the treatment of chronic HCV infection in Japanese patients: a randomized phase II/III study, JOURNAL OF GASTROENTEROLOGY, 52(4), 520-533, 201704
- Individual patient data meta-analysis of controlled attenuation parameter (CAP) technology for assessing steatosis, JOURNAL OF HEPATOLOGY, 66(5), 1022-1030, 201705
- Choline Deficiency Causes Colonic Type II Natural Killer T (NKT) Cell Loss and Alleviates Murine Colitis under Type I NKT Cell Deficiency, PLOS ONE, 12(1), 20170117
- Whole genome sequencing discriminates hepatocellular carcinoma with intrahepatic metastasis from multi-centric tumors, JOURNAL OF HEPATOLOGY, 66(2), 363-373, 201702
- Evaluation for the Clinical Efficacy of Colon Capsule Endoscopy in the Detection of Laterally Spreading Tumors, DIGESTION, 95(1), 43-48, 2017
- The practical management of chronic hepatitis C infection in Japan - dual therapy of daclatasvir plus asunaprevir, EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 11(2), 103-113, 201702
- Interferon Stimulated Genes and Innate Immune Activation Following Infection With Hepatitis B and C Viruses, JOURNAL OF MEDICAL VIROLOGY, 89(3), 388-396, 201703
- Efficacy and Safety of Daclatasvir Plus Asunaprevir Therapy for Chronic Hepatitis C Patients With Renal Dysfunction, JOURNAL OF MEDICAL VIROLOGY, 89(4), 665-671, 201704
- Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus, PLOS ONE, 12(3), 20170302
- Retrograde venography during balloon-occluded retrograde transvenous obliteration of gastric varices, MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES, 26(1), 1-6, 2017
- The relationship between HBcrAg and HBV reinfection in HBV related post-liver transplantation patients, JOURNAL OF GASTROENTEROLOGY, 52(3), 366-375, 201703
- The risk of transient postprandial oxyhypoglycemia in nonalcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 52(2), 253-262, 201702
- Daclatasvir/asunaprevir/beclabuvir fixed-dose combination in Japanese patients with HCV genotype 1 infection, JOURNAL OF GASTROENTEROLOGY, 52(3), 385-395, 201703
- Clinical impact and characteristics of the narrow-band imaging magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team, GASTROINTESTINAL ENDOSCOPY, 85(4), 816-821, 201704
- Mesenchymal Stem Cells Induce Epithelial to Mesenchymal Transition in Colon Cancer Cells through Direct Cell-to-Cell Contact, NEOPLASIA, 19(5), 429-438, 201705
- Clinical Usefulness of the VS Classification System Using Magnifying Endoscopy with Blue Laser Imaging for Early Gastric Cancer, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2017
- Why highly effective drugs are not enough: the need for an affordable solution to eliminating HCV, EXPERT REVIEW OF CLINICAL PHARMACOLOGY, 10(6), 583-594, 2017
- Increasing Risk of Osteoporotic Fracture Is Associated With Vascular Dysfunction and Abnormal Vascular Structure in Both Men and Women, CIRCULATION JOURNAL, 81(6), 862-+, 201706
- ITPA polymorphism effects on decrease of hemoglobin during sofosbuvir and ribavirin combination treatment for chronic hepatitis C, JOURNAL OF GASTROENTEROLOGY, 52(6), 746-753, 201706
- Characterization of miR-122-independent propagation of HCV, PLOS PATHOGENS, 13(5), 201705
- Impact of Hepatitis C Virus Eradication on the Clinical Outcome of Patients with Hepatitis C Virus-Related Advanced Hepatocellular Carcinoma Treated with Sorafenib, ONCOLOGY, 92(6), 335-346, 2017
- Endoscopic findings of the gastric mucosa during long-term use of proton pump inhibitor - a multicenter study, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 52(8), 828-832, 2017
- Randomized Phase 3 Trial of Ombitasvir/Paritaprevir/Ritonavir and Ribavirin for Hepatitis C Virus Genotype 2-Infected Japanese Patients, ADVANCES IN THERAPY, 34(6), 1449-1465, 201706
- Development of a Novel Site-Specific Pegylated Interferon Beta for Antiviral Therapy of Chronic Hepatitis B Virus, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61(6), 201706
- Usefulness of humanized cDNA-uPA/SCID mice for the study of hepatitis B virus and hepatitis C virus virology, JOURNAL OF GENERAL VIROLOGY, 98(5), 1040-1047, 201705
- Clinical usefulness of magnifying endoscopy for non-ampullary duodenal tumors, ENDOSCOPY INTERNATIONAL OPEN, 5(4), E297-E302, 201704
- Indications for Small-bowel Capsule Endoscopy in Patients with Chronic Abdominal Pain, INTERNAL MEDICINE, 56(12), 1453-1457, 2017
- Relation of the Bilateral Earlobe Crease to Endothelial Dysfunction, AMERICAN JOURNAL OF CARDIOLOGY, 119(12), 1983-1988, 20170615
- Liver fibrosis assessment by FibroScan compared with pathological findings of liver resection specimen in hepatitis C infection, HEPATOLOGY RESEARCH, 47(8), 767-772, 201707
- Decreased frequency and duration of tooth brushing is a risk factor for endothelial dysfunction, INTERNATIONAL JOURNAL OF CARDIOLOGY, 241, 30-34, 20170815
- Patients with early recurrence of hepatocellular carcinoma have poor prognosis, HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL, 16(3), 279-288, 201706
- Serological Evaluation of Gastric Cancer Risk Based on Pepsinogen and Helicobacter pylori Antibody: Relationship to Endoscopic Findings, DIGESTION, 95(4), 314-318, 2017
- Significance of non-alcoholic fatty liver disease in Crohn's disease: A retrospective cohort study, HEPATOLOGY RESEARCH, 47(9), 872-881, 201708
- Clinical usefulness of transabdominal ultrasonography prior to patency capsule for suspected small-bowel strictures, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 51(3), 281-287, 20160303
- Novel pH-sensitive multifunctional envelope-type nanodevice for siRNA-based treatments for chronic HBV infection, JOURNAL OF HEPATOLOGY, 64(3), 547-555, 201603
- Computer-aided diagnosis of colorectal polyp histology by using a real-time image recognition system and narrow-band imaging magnifying colonoscopy, GASTROINTESTINAL ENDOSCOPY, 83(3), 643-649, 201603
- Long-term outcomes after treatment for T1 colorectal carcinoma, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 31(3), 571-578, 201603
- Effect of tenofovir disoproxil fumarate on drug-resistant HBV clones, JOURNAL OF INFECTION, 72(1), 91-102, 201601
- A Patient with CTLA-4 Haploinsufficiency Presenting Gastric Cancer, JOURNAL OF CLINICAL IMMUNOLOGY, 36(1), 28-32, 201601
- Randomized comparison of daclatasvir plus asunaprevir versus telaprevir plus peginterferon/ribavirin in Japanese hepatitis C virus patients, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(1), 14-22, 201601
- Analysis of Hepatitis C Virus Genotype 1b Resistance Variants in Japanese Patients Treated with Paritaprevir-Ritonavir and Ombitasvir, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 60(2), 1106-1113, 201602
- Early events in hepatitis B virus infection: From the cell surface to the nucleus, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(2), 302-309, 201602
- Elimination of HCV via a non-ISG-mediated mechanism by vaniprevir and BMS-788329 combination therapy in human hepatocyte chimeric mice, VIRUS RESEARCH, 213, 62-68, 20160202
- An Analysis of Surgical Treatment for the Spontaneous Rupture of Hepatocellular Carcinoma, DIGESTIVE SURGERY, 33(1), 43-50, 2016
- Regression of Cecal MALT Lymphoma after Antibiotic Treatment in a Patient with Helicobacter pylori Infection, INTERNAL MEDICINE, 55(2), 135-139, 2016
- Preoperative Biliary Drainage in Cases of Borderline Resectable Pancreatic Cancer Treated with Neoadjuvant Chemotherapy and Surgery, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2016
- Development of hepatocellular carcinoma in patients with hepatitis C virus infection who achieved sustained virological response following interferon therapy: A large-scale, long-term cohort study, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(5), 1009-1015, 201605
- TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis, NATURE COMMUNICATIONS, 7, 201605
- Perinatal Resveratrol Supplementation to Spontaneously Hypertensive Rat Dams Mitigates the Development of Hypertension in Adult Offspring, HYPERTENSION, 67(5), 1045-1052, 201605
- Condition of muscularis mucosae is a risk factor for lymph node metastasis in T1 colorectal carcinoma, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 28(4), 1269-1276, 201404
- Efficacy of probucol for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label pilot study, HEPATOLOGY RESEARCH, 44(4), 429-435, 201404
- Endoscopic features and management of diminutive colorectal submucosal invasive carcinoma, DIGESTIVE ENDOSCOPY, 26, 78-83, 201404
- Clinicopathologic features of hyperplastic/serrated polyposis syndrome in Japan, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(11), 1693-1698, 201311
- Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice, JOURNAL OF GASTROENTEROLOGY, 48(11), 1259-1270, 201311
- Utility of controlled attenuation parameter measurement for assessing liver steatosis in Japanese patients with chronic liver diseases, HEPATOLOGY RESEARCH, 43(11), 1182-1189, 201311
- Relationship between Narrow-Band Imaging Magnifying Observation and Pit Pattern Diagnosis in Colorectal Tumors, DIGESTION, 87(1), 53-58, 2013
- Replication Study of 15 Recently Published Loci for Body Fat Distribution in the Japanese Population, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 20(4), 336-350, 2013
- Impact of interleukin-28B genotype on in vitro and in vivo systems of hepatitis C virus replication, HEPATOLOGY RESEARCH, 42(9), 841-853, 201209
- Role of Natural Killer T Cells in the Mouse Colitis-Associated Colon Cancer Model, SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 75(1), 16-26, 201201
- Telaprevir with peginterferon and ribavirin for treatment-naive patients chronically infected with HCV of genotype 1 in Japan, JOURNAL OF HEPATOLOGY, 56(1), 78-84, 201201
- Toward the Establishment of a Prediction System for the Personalized Treatment of Chronic Hepatitis C, JOURNAL OF INFECTIOUS DISEASES, 205(2), 204-210, 20120115
- Clinical outcomes of endoscopic submucosal dissection for rectal tumor close to the dentate line, GASTROINTESTINAL ENDOSCOPY, 76(2), 444-450, 201208
- Severe necroinflammatory reaction caused by natural killer cell-mediated Fas/Fas ligand interaction and dendritic cells in human hepatocyte chimeric mouse, HEPATOLOGY, 56(2), 555-566, 201208
- Clinical outcomes of endoscopic submucosal dissection and endoscopic mucosal resection for laterally spreading tumors larger than 20 mm, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(4), 734-740, 201204
- Clinical features and prognosis in patients with hepatocellular carcinoma that developed after hepatitis C virus eradication with interferon therapy, JOURNAL OF GASTROENTEROLOGY, 46(6), 799-808, 201106
- Common Genetic Polymorphism of ITPA Gene Affects Ribavirin-Induced Anemia and Effect of Peg-Interferon Plus Ribavirin Therapy, JOURNAL OF MEDICAL VIROLOGY, 83(6), 1048-1057, 201106
- Cutaneous complications after transcatheter arterial treatment for hepatocellular carcinoma via the internal mammary artery: how to avoid this complication, JAPANESE JOURNAL OF RADIOLOGY, 29(5), 307-315, 201106
- Influence of the rs738409 polymorphism in patatin-like phospholipase 3 on the treatment efficacy of non-alcoholic fatty liver disease with type 2 diabetes mellitus, HEPATOLOGY RESEARCH, 46(3), E146-E153, 201603
- Evaluation of Antibiotic Use to Prevent Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Cholangitis, HEPATO-GASTROENTEROLOGY, 62(138), 417-424, 2015
- Differences in serum microRNA profiles in hepatitis B and C virus infection, JOURNAL OF INFECTION, 70(3), 273-287, 201503
- Emerging treatments for chronic hepatitis C, JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 114(3), 204-215, 201503
- Towards safer and appropriate application of endoscopic submucosal dissection for T1 colorectal carcinoma as total excisional biopsy: Future perspectives, DIGESTIVE ENDOSCOPY, 27(2), 216-222, 201501
- Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity, Nature Communications, 6, 201501
- Inverse Association of IL28B Genotype and Liver mRNA Expression of Genes Promoting or Suppressing Antiviral State, JOURNAL OF MEDICAL VIROLOGY, 83(9), 1597-1607, 201109
- Rapid Emergence of Telaprevir Resistant Hepatitis C Virus Strain from Wildtype Clone In Vivo, HEPATOLOGY, 54(3), 781-788, 201109
- Statins induce apoptosis and inhibit proliferation in cholangiocarcinoma cells, INTERNATIONAL JOURNAL OF ONCOLOGY, 39(3), 561-568, 201109
- Flow-mediated vasodilation is augmented in a corkscrew collateral artery compared with that in a native artery in patients with thromboangiitis obliterans (Buerger disease), JOURNAL OF VASCULAR SURGERY, 54(6), 1689-1697, 201112
- Low Prevalence of Helicobacter pylori-negative Gastric Cancer among Japanese, HELICOBACTER, 16(6), 415-419, 201112
- Quantitative analysis of colorectal lesions observed on magnified endoscopy images, JOURNAL OF GASTROENTEROLOGY, 46(12), 1382-1390, 201112
- Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis B virus infection for the fiscal year 2008 in Japan, HEPATOLOGY RESEARCH, 40(1), 1-7, 201001
- Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis C virus infection for the fiscal year 2008 in Japan, HEPATOLOGY RESEARCH, 40(1), 8-13, 201001
- Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease, ATHEROSCLEROSIS, 206(2), 604-610, 200910
- ★, Adoptive immunotherapy with liver allograft-derived lymphocytes induces anti-HCV activity after liver transplantation in humans and humanized mice, JOURNAL OF CLINICAL INVESTIGATION, 119(11), 3226-3235, 200911
- Involvement of Epithelial Cell Transforming Sequence-2 Oncoantigen in Lung and Esophageal Cancer Progression, CLINICAL CANCER RESEARCH, 15(1), 256-266, 20090101
- FDG positron emission tomography/computed tomography for the detection of extrahepatic metastases from hepatocellular carcinoma, HEPATOLOGY RESEARCH, 39(2), 134-142, 200902
- Morbidly obese patient with non-alcoholic steatohepatitis-related cirrhosis who died from sepsis caused by dental infection of Porphyromonas gingivalis: A case report, HEPATOLOGY RESEARCH, 46(3), E210-E215, 201603
- MicroRNAs as Biomarkers for Liver Disease and Hepatocellular Carcinoma, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 17(3), 201603
- Functional Behavior of NKp46-Positive Intrahepatic Natural Killer Cells Against Hepatitis C Virus Reinfection After Liver Transplantation, TRANSPLANTATION, 100(2), 355-364, 201602
- Mouse model of proximal colon-specific tumorigenesis driven by microsatellite instability-induced Cre-mediated inactivation of Apc and activation of Kras, JOURNAL OF GASTROENTEROLOGY, 51(5), 447-457, 201605
- Clinical significance and validity of the subclassification for colorectal laterally spreading tumor granular type, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(5), 973-979, 201605
- ★, Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer, NATURE GENETICS, 48(5), 500-+, 201605
- Change in Imaging Findings on Angiography-Assisted CT During Balloon-Occluded Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma, CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 39(6), 865-874, 201606
- Relationship between serum triglyceride levels and endothelial function in a large community-based study, ATHEROSCLEROSIS, 249, 70-75, 201606
- CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 23(3), 309-319, 2016
- Hepatocellular carcinoma in Japanese patients with nonalcoholic fatty liver disease and alcoholic liver disease: multicenter survey, JOURNAL OF GASTROENTEROLOGY, 51(6), 586-596, 201606
- Reduced Human alpha-defensin 6 in Noninflamed Jejunal Tissue of Patients with Crohn's Disease, INFLAMMATORY BOWEL DISEASES, 22(5), 1119-1128, 201605
- Polidocanol injection therapy for small-bowel hemangioma by using double-balloon endoscopy, GASTROINTESTINAL ENDOSCOPY, 84(1), 163-167, 201607
- Interleukin-34 as a fibroblast-derived marker of liver fibrosis in patients with non-alcoholic fatty liver disease, SCIENTIFIC REPORTS, 6, 20160701
- Clinical usefulness of a single-use splinting tube for poor endoscope operability in deep colonic endoscopic submucosal dissection, ENDOSCOPY INTERNATIONAL OPEN, 4(6), E614-E617, 201606
- Comparison of Outcome of Hepatic Arterial Infusion Chemotherapy and Sorafenib in Patients with Hepatocellular Carcinoma Refractory to Transcatheter Arterial Chemoembolization, ANTICANCER RESEARCH, 36(7), 3523-3529, 201607
- Long-term outcomes after treatment for pedunculated-type T1 colorectal carcinoma: a multicenter retrospective cohort study, JOURNAL OF GASTROENTEROLOGY, 51(7), 702-710, 201607
- Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus, PLOS PATHOGENS, 12(5), 201605
- Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma, CANCER SCIENCE, 107(5), 601-608, 201605
- HBV culture and infectious systems, HEPATOLOGY INTERNATIONAL, 10(4), 559-566, 201607
- ADH1B and ALDH2 are associated with metachronous SCC after endoscopic submucosal dissection of esophageal squamous cell carcinoma, CANCER MEDICINE, 5(7), 1397-1404, 201607
- Useful condition of chromoendoscopy with indigo carmine and acetic acid for identifying a demarcation line prior to endoscopic submucosal dissection for early gastric cancer, BMC GASTROENTEROLOGY, 16, 20160719
- Hepatitis C virus dynamics and cellular gene expression in uPA-SCID chimeric mice with humanized livers during intravenous silibinin monotherapy, JOURNAL OF VIRAL HEPATITIS, 23(9), 708-717, 201609
- Daclatasvir and asunaprevir treatment improves liver function parameters and reduces liver fibrosis markers in chronic hepatitis C patients, HEPATOLOGY RESEARCH, 46(8), 758-764, 201607
- Improvement of renal dysfunction in a patient with hepatitis C virus-related liver cirrhosis by daclatasvir and asunaprevir combination therapy: A case report, HEPATOLOGY RESEARCH, 46(9), 944-948, 201608
- A randomized, controlled study of peginterferon lambda-1a/ribavirin +/- daclatasvir for hepatitis C virus genotype 2 or 3, SPRINGERPLUS, 5, 20160819
- Nitroglycerine-induced vasodilation in coronary and brachial arteries in patients with suspected coronary artery disease, INTERNATIONAL JOURNAL OF CARDIOLOGY, 219, 312-316, 20160915
- Three patients treated with daclatasvir and asunaprevir for recurrent hepatitis C after liver transplantation: Case report, HEPATOLOGY RESEARCH, 46(7), 707-712, 201606
- RNA Exosome Complex Regulates Stability of the Hepatitis B Virus X-mRNA Transcript in a Non-stop-mediated (NSD) RNA Quality Control Mechanism, JOURNAL OF BIOLOGICAL CHEMISTRY, 291(31), 15958-15974, 20160729
- Preoperative Fluorine 18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography for Prediction of Microvascular Invasion in Small Hepatocellular Carcinoma, JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 40(4), 524-530, 2016
- Long-term prognosis after endoscopic submucosal dissection for early gastric cancer in super-elderly patients, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 30(10), 4321-4329, 201610
- Endoscopic submucosal dissection for anorectal tumor with hemorrhoids close to the dentate line: a multicenter study of Hiroshima GI Endoscopy Study Group, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 30(10), 4425-4431, 201610
- Risk factors for esophageal stenosis after entire circumferential endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 30(9), 4049-4056, 201609
- Clinical impact of dual red imaging in colorectal endoscopic submucosal dissection: a pilot study, THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 9(5), 679-683, 201609
- Serum YKL-40 as a marker of liver fibrosis in patients with non-alcoholic fatty liver disease, SCIENTIFIC REPORTS, 6, 20161014
- Characteristics of non-obese non-alcoholic fatty liver disease: Effect of genetic and environmental factors, HEPATOLOGY RESEARCH, 46(10), 1011-1018, 201609
- Pharmacokinetics, efficacy and safety of daclatasvir plus asunaprevir in dialysis patients with chronic hepatitis C: pilot study, JOURNAL OF VIRAL HEPATITIS, 23(11), 850-856, 201611
- Interferon-stimulated gene of 20 kDa protein (ISG20) degrades RNA of Hepatitis B virus to impede the replication of HBV in vitro and in vivo, ONCOTARGET, 7(42), 68179-68193, 20161018
- Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection, JOURNAL OF GASTROENTEROLOGY, 51(11), 1073-1080, 201611
- Highly multiplexed CRISPR-Cas9-nuclease and Cas9-nickase vectors for inactivation of hepatitis B virus, GENES TO CELLS, 21(11), 1253-1262, 201611
- Clinical usefulness of narrow band imaging magnifying colonoscopy for assessing ulcerative colitis-associated cancer/dysplasia, ENDOSCOPY INTERNATIONAL OPEN, 4(11), E1183-E1187, 201611
- Third-Generation Capsule Endoscopy Outperforms Second-Generation Based on the Detectability of Esophageal Varices, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2016
- Vaniprevir plus peginterferon alfa-2b and ribavirin in treatment-experienced Japanese patients with hepatitis C virus genotype 1 (GT1b) infection: Phase 3 studies, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(10), 1674-1683, 201610
- A comparison of 4-Fr with 5-Fr endoscopic nasopancreatic drainage catheters: A randomized, controlled trial, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(10), 1783-1789, 201610
- Risk stratification of ventricular fibrillation in Brugada syndrome using noninvasive scoring methods, HEART RHYTHM, 13(10), 1947-1954, 201610
- Effects of ITPA polymorphism on decrease of hemoglobin during simeprevir, peg-interferon, and ribavirin combination treatment for chronic hepatitis C, HEPATOLOGY RESEARCH, 46(12), 1256-1263, 201611
- Combination therapies with daclatasvir and asunaprevir on NS3-D168 mutated HCV in human hepatocyte chimeric mice, ANTIVIRAL THERAPY, 21(4), 307-315, 2016
- Vascular Function and Intima-media Thickness of a Leg Artery in Peripheral Artery Disease: A Comparison of Buerger Disease and Atherosclerotic Peripheral Artery Disease, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 23(11), 1261-1269, 2016
- Genetic variations of aldehyde dehydrogenase 2 and alcohol dehydrogenase 1B are associated with the etiology of atrial fibrillation in Japanese, JOURNAL OF BIOMEDICAL SCIENCE, 23, 20161207
- Circulating level of pigment epithelium-derived factor is associated with vascular function and structure: A cross-sectional study, INTERNATIONAL JOURNAL OF CARDIOLOGY, 225, 91-95, 20161215
- Hepatitis C virus treatment update - A new era of all-oral HCV treatment, ADVANCES IN DIGESTIVE MEDICINE, 3(4), 153-160, 201612
- Endothelial Function Assessed by Automatic Measurement of Enclosed Zone Flow-Mediated Vasodilation Using an Oscillometric Method Is an Independent Predictor of Cardiovascular Events, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 5(12), 201612
- Protease Inhibitor Resistance Remains Even After Mutant Strains Become Undetectable by Deep Sequencing, JOURNAL OF INFECTIOUS DISEASES, 214(11), 1687-1694, 20161201
- Common Variant Near HEY2 Has a Protective Effect on Ventricular Fibrillation Occurrence in Brugada Syndrome by Regulating the Repolarization Current, CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 9(1), 201601
- Complete response to short-term sorafenib treatment alone for hepatocellular carcinoma with bone, lymph node, and peritoneum metastases, HEPATOLOGY RESEARCH, 46(13), 1402-1408, 201612
- Association between variants in the interferon lambda 4 locus and substitutions in the hepatitis C virus non-structural protein 5A, JOURNAL OF HEPATOLOGY, 63(3), 554-563, 201509
- Pulverized konjac glucomannan ameliorates oxazolone-induced colitis in mice, EUROPEAN JOURNAL OF NUTRITION, 54(6), 959-969, 201509
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- A multicenter, open-label, dose-ranging study to exploratively evaluate the efficacy, safety, and dose-response of tolvaptan in patients with decompensated liver cirrhosis, JOURNAL OF GASTROENTEROLOGY, 45(9), 979-987, 201009
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- Establishment of functional telomerase immortalized human hepatocytes and a hepatic stellate cell line for telomere-targeting anticancer drug development, CANCER SCIENCE, 101(7), 1678-1685, 201007
- HBx protein is indispensable for development of viraemia in human hepatocyte chimeric mice, JOURNAL OF GENERAL VIROLOGY, 91, 1854-1864, 201007
- Practical evaluation of a mouse with chimeric human liver model for hepatitis C virus infection using an NS3-4A protease inhibitor, JOURNAL OF GENERAL VIROLOGY, 91, 1668-1677, 201007
- Regular surveillance by imaging for early detection and better prognosis of hepatocellular carcinoma in patients infected with hepatitis C virus, JOURNAL OF GASTROENTEROLOGY, 45(1), 105-112, 201001
- Sarpogrelate Hydrochloride, a Selective 5-hydroxytryptamine(2A) Antagonist, Augments Autologous Bone Marrow Mononuclear Cell Implantation-induced Improvement in Endothelium-dependent Vasodilation in Patients With Critical Limb Ischemia, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 55(1), 56-61, 201001
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- Helicobacter pylori dupA and gastric acid secretion are negatively associated with gastric cancer development, JOURNAL OF MEDICAL MICROBIOLOGY, 59(12), 1484-1489, 201012
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- Zoledronic acid delays disease progression of bone metastases from hepatocellular carcinoma, HEPATOLOGY RESEARCH, 40(12), 1195-1203, 201012
- Amino Acid Substitution in Hepatitis C Virus Core Region and Genetic Variation Near the Interleukin 28B Gene Predict Viral Response to Telaprevir with Peginterferon and Ribavirin, HEPATOLOGY, 52(2), 421-429, 201008
- Classification of Corkscrew Collaterals in Thromboangiitis Obliterans (Buerger's Disease) - Relationship Between Corkscrew Type and Prevalence of Ischemic Ulcers, CIRCULATION JOURNAL, 74(8), 1684-1688, 201008
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- Importance of Serum Concentration of Adefovir for Lamivudine-Adefovir Combination Therapy in Patients with Lamivudine-Resistant Chronic Hepatitis B, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 54(8), 3205-3211, 201008
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- Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin., Hepatology, 52(2), 421-429, 20100801
- Impaired coronary microvascular endothelial function in men with metabolic syndrome., World J Cardiol, 26(7), 205-210, 20100701
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- Characteristics of esophageal squamous cell carcinomas and lugol-voiding lesions in patients with head and neck squamous cell carcinoma, J Clin Gastroenterol, 44(2), e27-33, 20100201
- A Water-soluble extract from culture medium of ganoderma lucidum mycelia suppresses the development of colorectal adenoma, Hiroshima J Med Sci, 59(1), 1--6, 20100101
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- Synchronous and Subsequent Lesions of Serrated Adenomas and Tubular Adenomas of the Colorectum, PATHOBIOLOGY, 77(5), 273-277, 2010
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- A Polymorphism in MAPKAPK3 Affects Response to Interferon Therapy for Chronic Hepatitis C, GASTROENTEROLOGY, 136(5), 1796-1805, 200905
- Clinical prevention of gastric cancer by Helicobacter pylori eradication therapy: a systematic review, JOURNAL OF GASTROENTEROLOGY, 44(5), 365-371, 200905
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- Deletion of angiotensin II type I receptor reduces hepatic steatosis, JOURNAL OF HEPATOLOGY, 50(6), 1226-1235, 200906
- Nifedipine Interferes with Migration of Vascular Smooth Muscle Cells via Inhibition of Pyk2-Src Axis, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 16(3), 230-238, 200906
- Predicting the response to 48-week combination therapy with peginterferon alpha-2b plus ribavirin from the estimated HCV RNA load index after negative serum change in genotype 1b hepatitis C patients, HEPATOLOGY RESEARCH, 39(6), 531-538, 200906
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- Successful hepatitis B vaccination in liver transplant recipients with donor-specific hyporesponsiveness, TRANSPLANT INTERNATIONAL, 22(8), 805-813, 200908
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- Comparison of detectability of small-bowel lesions between capsule endoscopy and double-balloon endoscopy for patients with suspected small-bowel disease, GASTROINTESTINAL ENDOSCOPY, 69(4), 857-865, 200904
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- Expression of multidrug resistance-associated protein 2 is involved in chemotherapy resistance in human pancreatic cancer, INTERNATIONAL JOURNAL OF ONCOLOGY, 33(6), 1187-1194, 200812
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- Systemic gemcitabine combined with intra-arterial low-dose cisplatin and 5-fluorouracil for advanced hepatocellular carcinoma: Seven cases, WORLD JOURNAL OF GASTROENTEROLOGY, 14(16), 2602-2608, 20080428
- Ablation of the Bach1 gene leads to the suppression of atherosclerosis in Bach1 and apolipoprotein E double knockout mice, HYPERTENSION RESEARCH, 31(4), 783-792, 200804
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- Risk factors for hepatocellular carcinoma in a Japanese population: A nested case-control study, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 17(4), 846-854, 200804
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- Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells, JOURNAL OF GASTROENTEROLOGY, 43(4), 298-304, 2008
- Combination therapy of oral fluoropyrimidine anticancer drug S-1 and interferon alpha for HCC patients with extrahepatic metastases, ONCOLOGY, 75(1-2), 8-16, 2008
- Evaluation of colon cancer vascularity by flash echo imaging, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 43(2), 223-228, 2008
- Predictors and long-term prognostic implications of angiographic slow/no-flow during percutaneous coronary intervention for acute myocardial infarction, INTERNAL MEDICINE, 47(10), 899-906, 2008
- Relation between histologic gastritis and gastric motility in Japanese patients with functional dyspepsia: evaluation by transabdominal ultrasonography, JOURNAL OF GASTROENTEROLOGY, 43(5), 332-337, 2008
- Role of the Gastrin-Gastrin Receptor System in the Expansive Growth of Human Gastric Neoplasms, DIGESTION, 78(2-3), 163-170, 2008
- Validating a Markov Model of Treatment for Hepatitis C Virus-related Hepatocellular Carcinoma, METHODS OF INFORMATION IN MEDICINE, 47(6), 529-540, 2008
- Pycnogenol (R), French maritime pine bark extract, augments endothelium-dependent vasodilation in humans, HYPERTENSION RESEARCH, 30(9), 775-780, 200709
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- Low-dose intermittent interferon-alpha therapy for HCV-related liver cirrhosis after curative treatment of hepatocellular carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(39), 5188-5195, 20071021
- Nodular gastritis with Helicobacter pylori infection is strongly associated with diffuse-type gastric cancer in young patients, DIGESTIVE ENDOSCOPY, 19(4), 180-184, 200710
- Pretreatment predictor of response, time to progression, and survival to intraarterial 5-fluorouracil/interferon combination therapy in patients with advanced hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY, 42(10), 845-853, 200710
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- Similar effects of recombinant interferon-alpha-2b and natural interferon-alpha when combined with intra-arterial 5-fluorouracil for the treatment of advanced hepatocellular carcinoma, LIVER INTERNATIONAL, 27(9), 1209-1216, 200711
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- Endoscopic submucosal dissection for colorectal neoplasia: possibility of standardization, GASTROINTESTINAL ENDOSCOPY, 66(1), 100-107, 200707
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- Basis of decreased risk of gastric cancer in severe atrophic gastritis with eradication of Helicobacter pylori, DIGESTIVE DISEASES AND SCIENCES, 52(1), 232-239, 200701
- Gene delivery of paraoxonase-1 inhibits neointimal hyperplasia after arterial balloon-injury in rabbits fed a high-fat diet, HYPERTENSION RESEARCH, 30(1), 85-91, 200701
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- Cavernous hemangioma in the ascending colon treated by endoscopic mucosal resection, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(2), 280-281, 200702
- Dual effect of APOBEC3G on Hepatitis B virus, JOURNAL OF GENERAL VIROLOGY, 88, 432-440, 200702
- Immune response to CagA protein is associated with improved platelet count after Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura, HELICOBACTER, 12(1), 36-42, 200702
- Roles of Rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 49(6), 698-705, 20070213
- Selective decrease in colonic CD56(+) T and CD161(+) T cells in the inflamed mucosa of patients with ulcerative colitis, WORLD JOURNAL OF GASTROENTEROLOGY, 13(45), 5995-6002, 20071207
- Single lymphocyte analysis with a microwell array chip, CYTOMETRY PART A, 71A(12), 1003-1010, 200712
- Successful treatment of an entecavir-resistant hepatitis B virus variant, JOURNAL OF MEDICAL VIROLOGY, 79(12), 1811-1817, 200712
- Involvement of Kruppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma, WORLD JOURNAL OF GASTROENTEROLOGY, 13(29), 3932-3938, 20070807
- Acute moderate-intensity exercise induces vasodilation through oxide bioavailiability an increase in nitric in humans, AMERICAN JOURNAL OF HYPERTENSION, 20(8), 825-830, 200708
- Low serum level of hepatitis B indicates unlikely reactivation core-related antigen of hepatitis after cessation of lamivudine therapy, HEPATOLOGY RESEARCH, 37(8), 661-666, 200708
- The long-term outcome of patients with bleeding gastric varices after balloon-occluded retrograde transvenous obliteration, JOURNAL OF GASTROENTEROLOGY, 42(8), 663-672, 200708
- Host factors contributing to the discovery of gastric cancer after successful eradication therapy of Helicobacter pylori: Preliminary report, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 22(4), 571-576, 200704
- New method of evaluating gastric mucosal blood flow by ultrasound, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 42(4), 513-518, 200704
- Pycnogenol, French maritime pine bark extract, augments endothelium-dependent vasodilation in humans., HYPERTENSION RESEARCH, 775-780, 20070901
- Predicting the need for surgery in Crohn's disease with contrast harmonic ultrasound, Scand J Gastroenterol, 42, 577-585, 20070601
- Should splenectomy be performed for hepatitis C patients undergoing living-donor liver transplantation, J Gastroenterol Hepatol, 22(6), 959-960, 20070601
- Helicobacter pylori-associated gastritisis related to babA2expression without heterogeneity of the 3' region of the cagA genotype in Gastric Biopsy Specimens, Pathobiology, 74(5), 1-7, 20070401
- The effects of different intensities of acute exercise on systemic hemodynamics and forearm vascular function in humans., AMERICAN JUORNAL OF HYPERTENSION, 825-830, 20070214
- Carvedilol improves endothelium-dependent vasodilation in patients with dilated cardiomyopathy., HEART, 247-248, 20070201
- Balloon-occluded retrograde transvenous obliteration for portal-systemic encephalopathy due to superior mesenteric-caval shunt via the right gonadal vein, INTERNAL MEDICINE, 46(17), 1479-1480, 2007
- Efficacy of percutaneous cementoplasty for bone metastasis from hepatocellular carcinoma, ONCOLOGY, 72(5-6), 285-292, 2007
- Eicosapentaenoic acid could permit maintenance of the original ribavirin dose in chronic hepatitis C virus patients during the first 12 weeks of combination therapy with pegylated interferon-alpha and ribavirin, INTERVIROLOGY, 50(6), 439-446, 2007
- Helicobacter pylori - Associated gastritis is related to babA2 expression without heterogeneity of the 3 ' region of the cagA genotype in gastric biopsy specimens, PATHOBIOLOGY, 74(5), 309-316, 2007
- Predicting the need for surgery in Crohn's disease with contrast harmonic ultrasound, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 42(5), 577-585, 2007
- A case of Crohn's disease with hydronephrosis caused by ureteropelvic junction obstruction, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 18(9), 1015-1018, 200609
- A ligand for peroxisome proliferator-activated receptor gamma inhibits human cholangiocarcinoma cell growth: Potential molecular targeting strategy for cholangioma, DIGESTIVE DISEASES AND SCIENCES, 51(9), 1650-1657, 200609
- Helicobacter pylori infection is the major risk factor for gastric inflammation in the cardia, DIGESTIVE DISEASES AND SCIENCES, 51(9), 1582-1588, 200609
- Medical malpractice litigation in gastroenterological practice in Japan: A 22-yr review of civil court cases, AMERICAN JOURNAL OF GASTROENTEROLOGY, 101(9), 1951-1953, 200609
- Autologous bone marrow mononuclear cell implantation induces angiogenesis and bone regeneration in a patient with compartment syndrome, CIRCULATION JOURNAL, 70(10), 1362-1364, 200610
- Endoscopic submucosal dissection for residual/local recurrence of early gastric cancer after endoscopic mucosal resection, ENDOSCOPY, 38(10), 996-1000, 200610
- Genetic progression and divergence in superficial esophageal squamous cell carcinoma by loss of heterozygosity analysis, ONCOLOGY REPORTS, 16(4), 685-691, 200610
- High-magnification colonoscopy (with videos), GASTROINTESTINAL ENDOSCOPY, 64(4), 604-613, 200610
- Management of intraductal papillary-mucinous neoplasm of the pancreas - Treatment strategy based on morphologic classification, JOURNAL OF CLINICAL GASTROENTEROLOGY, 40(9), 856-862, 200610
- Aged garlic extract has potential suppressive effect on colorectal adenomas in humans, JOURNAL OF NUTRITION, 136(3), 821S-826S, 200603
- Deletion of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach, INTERNATIONAL JOURNAL OF ONCOLOGY, 28(6), 1361-1367, 200606
- Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production, ATHEROSCLEROSIS, 186(2), 390-395, 200606
- Measurement of hepatitis B virus core-related antigen is valuable for identifying patients who are at low risk of lamivudine resistance, LIVER INTERNATIONAL, 26(1), 90-96, 200602
- Nonpolypoid (flat and depressed) colorectal neoplasms, GASTROENTEROLOGY, 130(2), 566-576, 200602
- Suppression of STAT3 activity by duplin, which is a negative regulator of the Wnt signal, JOURNAL OF BIOCHEMISTRY, 139(2), 305-314, 200602
- The nicorandil-induced vasodilation in humans is inhibited by miconazole, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 45(4), 290-294, 200504
- Expression of p53 protein in esophageal squamous cell carcinoma: relation to hypoxia-inducible factor-1alpha, angiogenesis and apoptosis., Pathobiology, 72, 179-185, 20050901
- Ablation of ventricular tachycardia originating from the right ventricle associated with scleroderma cardiomyopathy., J Arrhythmia, 21(5), 542-545, 20050401
- Angiotensin II type I receptor blocker and endothelial function in humans: role of nitric oxide and oxidative stress., Curr.Med.Chem, 3(2), 133-148, 20050401
- Relationship between histopathological features and type V pit pattern determined by magnifying videocolonoscopy in early colorectal carcinoma, Dig Endos, 17, 117-122, 20050401
- Effects of angiotensin II on the expression of MCP-1 in hepatic stellate line LI90, Japanese Pharmaology and Therapeutics, 32, 143-5, 20050201
- Molecular evolutionaly analyses implicate injecthion treatment for schistosomiasis in the initial hepatitis C epidemics in japan, Journal of Hepatology, 42, 47-53, 20050101
- Superficial type serrated adenoma in ulcerative colitis resected by endoscopic submucosal dissection, Dig Endosc, 17, S49-S52, 20050101
- A classification system of echogenicity for gastrointestinal neoplasms, DIGESTION, 72(1), 8-12, 2005
- Expression of p53 protein in esophageal squamous cell carcinoma: Relation to hypoxia-inducible factor-1 alpha, angiogenesis and apoptosis, PATHOBIOLOGY, 72(4), 179-185, 2005
- Effect of different intensities of exercise on endothelium-dependent vasodilation in humans - Role of endothelium-dependent nitric oxide and oxidative stress, CIRCULATION, 108(5), 530-535, 20030805
- Impact of aging on the development of hepatocellular carcinoma in patients with hepatitis C virus infection in Japan, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(8), 894-900, 200308
- Vascular endothelial growth factor-C expression predicts lymph node metastasis of human gastric carcinomas invading the submucosa, EUROPEAN JOURNAL OF CANCER, 38(10), 1413-1419, 200207
- p53 codon 72 polymorphism in gastric cancer susceptibility in patients with Helicobacter pylori-associated chronic gastritis, INTERNATIONAL JOURNAL OF CANCER, 100(3), 304-308, 20020720
- Genotype, slow decrease in virus titer during interferon treatment and high degree of sequence variability of hypervariable region are indicative of poor response to interferon treatment in patients with chronic hepatitis type C, J Hepatol, 23, 648-653, 19950401
- Genotyping of hepatitis C virus by the polymerase chain reaction: a comparison of two PCR-based methods using core or NS5 primers, Int Hepatol Commun, 4, 67-71, 19950401
- Molecular analysis of intraspousal transmission of hepatitis C virus, J Hepatol, 22, 431-439, 19950401
- Novel hepatitis B variants in sibling carriers positive for antibody to hepatitis B surface antigen, Int Hepatol Commun, 4, 121-125, 19950401
- Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 346(1), 67-73, 20060721
- A case of multiple hepatic peribiliary cysts which contributed to the obstructive jaundice and led to liver failure at the young man with von Recklinghausen's disease, HEPATOLOGY RESEARCH, 35(3), 222-227, 200607
- Clinicopathologic and genetic characteristics of gastric cancer in young male and female patients, ONCOLOGY REPORTS, 16(1), 11-15, 200607
- Double-balloon enteroscopy in patients with GI bleeding of obscure origin, GASTROINTESTINAL ENDOSCOPY, 64(1), 135-140, 200607
- Gastrointestinal stromal tumor in jejunum: Diagnosis using contrast-enhanced ultrasonography and double-balloon enteroscopy, DIGESTIVE DISEASES AND SCIENCES, 51(7), 1236-1240, 200607
- Neuropilin-1 is involved in regulation of apoptosis and migration of human colon cancer, INTERNATIONAL JOURNAL OF ONCOLOGY, 29(1), 105-116, 200607
- Real-time visualization and quantitation of canine gastric mucosal blood flow by contrast-enhanced ultrasonography, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 41(7), 856-861, 200607
- dEvaluation of endoscopic and histological findings in Helicobacter pylori-positive Japanese young adults, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 21(1), 258-261, 200601
- Defensive medicine practices among gastroenterologists in Japan, WORLD JOURNAL OF GASTROENTEROLOGY, 12(47), 7671-7675, 20061221
- Advantage of endoscopic submucosal dissection compared with EMR for early gastric cancer, GASTROINTESTINAL ENDOSCOPY, 64(6), 877-883, 200612
- Feasibility of freeze-dried sera for serological and molecular biological detection of hepatitis B and C viruses, JOURNAL OF CLINICAL MICROBIOLOGY, 44(12), 4593-4595, 200612
- Genetic and pathologic characteristics of gastrointestinal stromal tumors in extragastric lesions, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 18(6), 1067-1071, 200612
- Small-intestinal Peutz-Jeghers polyps resected by endoscopic polypectomy with double-balloon enteroscopy and removal confirmed by ultrasonography, DIGESTIVE DISEASES AND SCIENCES, 51(12), 2337-2340, 200612
- Effects of acute administration of caffeine on vascular function, AMERICAN JOURNAL OF CARDIOLOGY, 98(11), 1538-1541, 20061201
- Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 346(3), 658-664, 20060804
- Oxidative stress, endothelial function and angiogenesis induced by cell therapy and gene therapy, CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 7(2), 109-116, 200604
- The effect of Helicobacter pylori eradication therapy on gastric ulcer healing after endoscopic mucosal resection, JOURNAL OF CLINICAL GASTROENTEROLOGY, 40(4), 293-296, 200604
- The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines, INTERNATIONAL JOURNAL OF ONCOLOGY, 28(4), 915-921, 200604
- The usefulness of transabdominal ultrasound for the diagnosis of lower gastrointestinal bleeding, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 23(8), 1267-1272, 20060415
- High-magnification colonoscopy (with Videos), Gastrointest Endosc, 64(4), 604-613, 20061001
- Management of Intraductal Papillary -mucinous Neoplasm of the Pancreas, J Clin Gastroenterol, 40(9), 856-862, 20061001
- Suppression of interferon-related promoter activation by hepatitis C virus proteins expressed in cultured cells., Hiroshima Journal of Medical Sciences, 55(3), 71-77, 20060901
- Pit pattern diagnosis for colorectal neoplasia using narrow band imaging magnification, Dig Endosc, 18, S52-S56, 20060701
- Delection of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach., Int J Oncology, 28, 1361-1367, 20060601
- Ablation of indiopathic ventricular tachycardia with a left Bundle-Branch block morphology originating from the pulmonary artery., J Arrthmia, 22(3), 180-186, 20060401
- Coronary sinus Morphology in Patients with Posteroseptal Atrioventricular Accessory Pathways., J Arrthmia, 22(3), 149-154, 20060401
- Edaravone(3-Methyl-1-Phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases., Recent Patents on Cardiovascular Drug Discovery, 1, 85-93, 20060401
- Helicobacter pylori infection is the major risk factor for atrophic gastritis, San Diego, 20060301
- Causal role of Helicobacter pylori infection and eradication therapy in gastric carcinogenesis., World J Gastroenterol, 12(1), 10-16, 20060101
- Evaluation of endoscopic and histological findings in Helicobacter pylori-positive Japanese young adults, J Gastroenterol Hepatol, 21, 258-261, 20060101
- Development of a novel method to detect Helicobacter pylori cagA genotype from paraffin-embedded materials: Comparison between patients with duodenal ulcer and gastric cancer in young Japanese, DIGESTION, 73(1), 47-53, 2006
- Evolution of hepatitis C virus quasispecies during ribavirin and interferon-alpha-2b combination therapy and interferon-alpha-2b monotherapy, INTERVIROLOGY, 49(6), 352-361, 2006
- Nuclear and mitochondrial DNA microsatellite instability in gastrointestinal stromal tumors, PATHOBIOLOGY, 73(2), 93-97, 2006
- Prolonged negative HCV-RNA status led to a good outcome in chronic hepatitis C patients with genotype 1b and super-high viral load, INTERVIROLOGY, 49(6), 362-369, 2006
- Successive, rapid recurrences of in-stent restenoses in a woman with angina pectoris, INTERNAL MEDICINE, 45(19), 1093-1096, 2006
- Cardiac glands hyperplastic polyp of the stomach, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(9), 1461-1463, 200509
- ★, A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5 ' flanking region of SMYD3 is a risk factor for human cancers, NATURE GENETICS, 37(10), 1104-1107, 200510
- Adrenomedullin causes coronary vasodilation in humans - Effects of inhibition of nitric oxide synthesis, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 46(4), 534-539, 200510
- Diagnostic ability of high-frequency ultrasound probe sonography in staging early gastric cancer, especially for submucosal invasion, ABDOMINAL IMAGING, 30(5), 518-523, 200510
- Relationship between endothelial function in the coronary and brachial arteries, CLINICAL CARDIOLOGY, 28(10), 460-466, 200510
- Therapeutic effect of repeated natural killer T cell stimulation in mouse cholangitis complicated by colitis, DIGESTIVE DISEASES AND SCIENCES, 50(10), 1844-1851, 200510
- Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus, HEPATOLOGY, 42(5), 1046-1054, 200511
- Reliable and cost-effective screening of inherited heterozygosity by Zn2+-cyclen polyacrylamide gel electrophoresis, CLINICAL CHEMISTRY, 51(11), 2195-2198, 200511
- Somatic mutations of mitochondrial DNA in digestive tract cancers, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(11), 1679-1684, 200511
- Monocyte chemoattractant protein-1 transfection induces angiogenesis and tumorigenesis of gastric carcinoma in nude mice via macrophage recruitment, CLINICAL CANCER RESEARCH, 11(21), 7629-7636, 20051101
- Role of the JNK pathway in thrombin-induced ICAM-1 expression in endothelial cells, CARDIOVASCULAR RESEARCH, 68(2), 289-298, 20051101
- Angiotensin II participates in hepatic inflammation and fibrosis through MCP-1 expression, DIGESTIVE DISEASES AND SCIENCES, 50(5), 942-948, 200505
- Clinical features of gastric cancer discovered after successful eradication of Helicobacter pylori: results from a 9-year prospective follow-up study in Japan, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21(9), 1121-1126, 20050501
- Involvement of proinflammatory cytokines IL-1 beta and IL-6 in progression of human gastric carcinoma, ANTICANCER RESEARCH, 25(2A), 709-713, 2005
- A nuclear receptor ligand down-regulates cytosolic phospholipase A(2) expression to reduce bile acid-induced cyclooxygenase 2 activity in cholangiocytes: Implications of anticarcinogenic action of farnesoid X receptor agonists, DIGESTIVE DISEASES AND SCIENCES, 50(3), 514-524, 200503
- G to A hypermutation of hepatitis B virus, HEPATOLOGY, 41(3), 626-633, 200503
- Ubquitin-interacting motifs of epsin are involved in the regulation of insulin-dependent endocytosis, JOURNAL OF BIOCHEMISTRY, 137(3), 355-364, 200503
- Morphological changes in human gastric tumours after eradication therapy of Helicobacter pylori in a short-term follow-up, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21(5), 559-566, 20050301
- Effect of famotidine on recurrent bleeding after successful endoscopic treatment of bleeding peptic ulcer, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21, 73-78, 200506
- Effect of long-term half-dose famotidine therapy on corpus gastritis in peptic ulcer disease, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21, 99-104, 200506
- Quantitative analysis of lymphangiogenic markers for predicting metastasis of human gastric carcinoma to lymph nodes, INTERNATIONAL JOURNAL OF CANCER, 115(3), 388-392, 20050620
- Hepatitis C virus core protein modulates fatty acid metabolism and thereby causes lipid accumulation in the liver, DIGESTIVE DISEASES AND SCIENCES, 50(7), 1361-1371, 200507
- A case of congenital absence of the portal vein, HEPATOLOGY RESEARCH, 31(1), 43-47, 200501
- A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer, JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 131(1), 19-25, 200501
- Eradication of Helicobacter pylori increases the incidence of hyperlipidaemia and obesity in peptic ulcer patients, DIGESTIVE AND LIVER DISEASE, 37(1), 39-43, 200501
- Infliximab therapy for Crohn's disease in a patient with chronic hepatitis B, DIGESTIVE DISEASES AND SCIENCES, 50(1), 163-166, 200501
- Molecular evolutionary analyses implicate injection treatment for schistosomiasis in the initial hepatitis C epidemics in Japan, JOURNAL OF HEPATOLOGY, 42(1), 47-53, 200501
- Single dose of OCH improves mucosal T helper type 1/T helper type 2 cytokine balance and prevents experimental colitis in the presence of v alpha 14 natural killer T cells in mice, INFLAMMATORY BOWEL DISEASES, 11(1), 35-41, 200501
- Suppression of macrophage infiltration inhibits activation of hepatic stellate cells and liver fibrogenesis in rats, GASTROENTEROLOGY, 128(1), 138-146, 200501
- Vascular function in patients with lower extremity peripheral arterial disease: a comparison of functions in upper and lower extremities, ATHEROSCLEROSIS, 178(1), 179-185, 200501
- Biphasic effect of HMG-CoA reductase inhibitor, pitavastatin, on vascular endothelial cells and angiogenesis, CIRCULATION JOURNAL, 69(12), 1547-1555, 200512
- Smoking, endothelial function, and Rho-kinase in humans, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 25(12), 2630-2635, 200512
- Glycochenodeoxycholate plays a carcinogenic role in immortalized mouse cholanglocytes via oxidative DNA damage, FREE RADICAL BIOLOGY AND MEDICINE, 39(11), 1418-1427, 20051201
- Expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in early gastric carcinoma: correlation with clinicopathological parameters, CANCER LETTERS, 226(1), 85-90, 20050808
- A nuclear receptor-mediated choleretic action of fibrates is associated with enhanced canalicular membrane fluidity and transporter activity mediating bile acid-independent bile secretion, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 12(4), 211-217, 20050825
- A combination of the Helicobacter pylori stool antigen test and urea breath test is useful for clinical evaluation of eradication therapy: A multicenter study, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(8), 1241-1245, 200508
- Multiple carcinoid tumors of the ileum preoperatively diagnosed by enteroscopy with the double-balloon technique, GASTROINTESTINAL ENDOSCOPY, 62(2), 315-318, 200508
- Loss of heterozygosity on chromosome 10p14-p15 in colorectal carcinoma, PATHOBIOLOGY, 72(4), 220-224, 2005
- Improvement of atrial signal-averaged electrocardiographic abnormalities after radiofrequency catheter ablation in persistent atrial flutter, JAPANESE HEART JOURNAL, 45(5), 761-770, 200409
- Concise prediction models of anticancer efficacy of 8 drugs using expression data from 12 selected genes, INTERNATIONAL JOURNAL OF CANCER, 111(4), 617-626, 20040910
- Partial characterization of cytoprotective mechanisms of lecithin against bile salt-induced bile duct damage, JOURNAL OF GASTROENTEROLOGY, 39(10), 955-960, 200410
- Effect of edaravone, a novel free radical scavenger, on endothelium-dependent vasodilation in smokers, AMERICAN JOURNAL OF CARDIOLOGY, 94(8), 1070-1073, 20041015
- Apolipoprotein E phenotype affects the malondialdehyde-modified LDL concentration and forearm endothelial function in postmenopausal women, CLINICAL ENDOCRINOLOGY, 61(5), 619-625, 200411
- Magnifying colonoscopic features of ulcerative colitis reflect histologic inflammation, INFLAMMATORY BOWEL DISEASES, 10(6), 737-744, 200411
- A case of latent primary biliary cirrhosis, HEPATOLOGY RESEARCH, 28(3), 166-169, 200403
- Atrial contraction after surgical isolation of the left atrial posterior wall concomitant with mitral valve replacement, CIRCULATION JOURNAL, 68(3), 204-207, 200403
- Clinical significance of angiopoietin-2 expression at the deepest invasive tumor site of advanced colorectal carcinoma, INTERNATIONAL JOURNAL OF ONCOLOGY, 24(3), 539-547, 200403
- Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia, CIRCULATION, 109(10), 1215-1218, 20040316
- Fas and Fas ligand: Expression and soluble circulating levels in bile duct carcinoma, ONCOLOGY REPORTS, 11(6), 1183-1186, 200406
- Initial experience with catheter probe US when using a multibending endoscope, GASTROINTESTINAL ENDOSCOPY, 59(7), 889-894, 200406
- Induction of apoptosis by ionizing radiation and CI-1033 in HuCCT-1 cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 319(1), 114-119, 20040618
- Chronic gastritis with expression of inducible nitric oxide synthase is associated with high expression of interleukin-6 and hypergastrinaemia, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 19(12), 1309-1314, 20040615
- Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma, INTERNATIONAL JOURNAL OF CANCER, 110(2), 212-218, 20040610
- Chromosomal and microsatellite instability in sporadic gastric cancer, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 19(7), 756-760, 200407
- Regulation of vascular endothelial growth factor (VEGF)-C and VEGF-D expression by the organ microenvironment in human colon carcinoma, EUROPEAN JOURNAL OF CANCER, 40(10), 1604-1609, 200407
- Relation between C reactive protein concentrations and coronary microvascular endothelial function, HEART, 90(7), 750-754, 200407
- Expression of human telomerase reverse transcriptase mRNA in esophageal cancers and precancerous lesions, ONCOLOGY REPORTS, 11(1), 51-55, 200401
- Expression of VEGF-C and VEGF-D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma, CANCER SCIENCE, 95(1), 32-39, 200401
- Gemcitabine suppresses malignant ascites of human pancreatic cancer: Correlation with VEGF expression in ascites, ONCOLOGY REPORTS, 11(1), 73-80, 200401
- Angiogenic switch occurs during the precancerous stage of human esophageal squamous cell carcinoma, ONCOLOGY REPORTS, 11(2), 315-319, 200402
- Clinicopathologic and endoscopic features of colorectal serrated adenoma: differences between polypoid and superficial types, GASTROINTESTINAL ENDOSCOPY, 59(2), 213-219, 200402
- Mutation of the von Hippel-Lindau (VHL) gene in human colorectal carcinoma: Association with cytoplasmic accumulation of hypoxia-inducible factor (HIF)-1 alpha, CANCER SCIENCE, 95(2), 149-153, 200402
- Epigenetic inactivation of SOCS-1 by CpG island hypermethylation in human gastric carcinoma, INTERNATIONAL JOURNAL OF CANCER, 112(6), 1003-1009, 20041220
- Expression of hypoxia-inducible factor (HIF)-1 alpha is associated with vascular endothelial growth factor expression and tumour anglogenesis in human oesophageal squamous cell carcinoma, EUROPEAN JOURNAL OF CANCER, 40(12), 1904-1912, 200408
- Frequent loss of heterozygosity on chromosome 10p14-p15 in esophageal dysplasia and squamous cell carcinoma, ONCOLOGY REPORTS, 12(2), 333-337, 200408
- Immune response in mouse experimental cholangitis associated with colitis induced by dextran sulfate sodium, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 19(8), 910-915, 200408
- Identification of rare polymerase variants of hepatitis B virus using a two-stage PCR with peptide nucleic acid clamping, JOURNAL OF MEDICAL VIROLOGY, 72(4), 558-565, 200404
- Magnifying gastroendoscopy for diagnosis of histologic gastritis in the gastric antrum, DIGESTIVE AND LIVER DISEASE, 36(4), 286-291, 200404
- Sonographic detection of longitudinal ulcers in Crohn disease, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 39(4), 322-326, 200404
- Expression of hypoxia-inducible factor (HIF)-1alpha is associated with vascular endothelial growth factor expression and tumour angiogenesis in human oesophageal squamous cell carcinoma., Eur J Cancer, 40, 1904-1912, 20040801
- Relationship between C-reactive protein concetrations and coronary microvascular endothelial function0, Heart, 90, 750-754, 20040701
- Effects of aged garlic extract (AGE) on colorectal adenomas: a double-blinded study, Hiroshima J Med Sci, 53(3--4), 39-45, 20040401
- Pathophysiology of nonalcoholic steatohepatitis (NASH)-Relation to adipocytokine and advanced glycation end products., Japanese Pharmaology & Therapeutics, 32, 107-9, 20040201
- Clinical usefulness of high-frequency ultrasound probes for new invasion depth diagnosis in submucosal colorectal carcinoma, Dig Endosc, 16, S49-S52, 20040101
- Characteristics and trends of clarithromycin-resistant Helicobacter pylori isolates in Japan over a decade, PATHOBIOLOGY, 71(3), 159-163, 2004
- Frequent loss of RUNX3 expression by promoter hypermethylation in gastric carcinoma, PATHOBIOLOGY, 71(3), 137-143, 2004
- Mucin phenotype and background mucosa of intramucosal differentiated-type adenocarcinoma of the stomach, ONCOLOGY, 66(5), 379-387, 2004
- Frequent loss of heterozygosity on chromosome 10p15, a putative telomerase repressor/senescence gene locus, in gastric cancer, ONCOLOGY REPORTS, 10(5), 1297-1299, 2003
- Prognostic value of p53 and Ki-67 expression in resected or biopsy specimens of bile duct carcinoma, ONCOLOGY REPORTS, 10(5), 1091-1096, 2003
- Does intragastric nitrite concentration reflect gastric carcinogenesis in Japanese Helicobacter pylori-infected patients?, DIGESTIVE DISEASES AND SCIENCES, 48(9), 1730-1736, 200309
- Gastric juice nitrite and vitamin C in patients with gastric cancer and atrophic gastritis: is low acidity solely responsible for cancer risk?, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 15(9), 987-993, 200309
- Necessity of multiple gastric biopsies from different sites for detection of clarithromycin-resistant Helicobacter pylori strains, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(9), 942-946, 200309
- p53 expression, K-ras gene mutation and microsatellite instability in gastric B-cell lymphomas, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 18(9), 1047-1053, 200309
- Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 12(4), 437-442, 200310
- Clinical significance of thrombospondin-1 expression in relation to vascular endothelial growth factor and interleukin-10 expression at the deepest invasive tumor site of advanced colorectal carcinoma, INTERNATIONAL JOURNAL OF ONCOLOGY, 23(4), 901-911, 200310
- Disruption of the type 2 dopamine receptor gene causes a sodium-dependent increase in blood pressure in mice, AMERICAN JOURNAL OF HYPERTENSION, 16(10), 853-858, 200310
- Prevalence of Helicobacter pylori resistance to clarithromycin and metronidazole determined by 23S ribosomal RNA and rdxA gene analyses in Hiroshima, Japan, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 18(10), 1202-1207, 200310
- The promoter methylation status of the DNA repair gene O-6-methylguanine-DNA methyltransferase in ulcerative colitis, VIRCHOWS ARCHIV, 443(4), 518-523, 200310
- Clinicopathologic features and endoscopic resection of early primary nonampullary duodenal carcinoma, JOURNAL OF CLINICAL GASTROENTEROLOGY, 37(5), 381-386, 2003
- Somatic mutation in mitochondrial DNA and nuclear microsatellite instability in gastric cancer, ONCOLOGY REPORTS, 10(6), 1837-1841, 2003
- Helicobacter pylori infection influences expression of genes related to angiogenesis and invasion in human gastric carcinoma cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 311(4), 809-814, 20031128
- Expressions of angiogenic factors in pancreatic ductal carcinoma: A correlative study with clinicopathologic parameters and patient survival, PANCREAS, 26(4), 344-349, 200305
- Nodular gastritis in adults is caused by Helicobacter pylori infection, DIGESTIVE DISEASES AND SCIENCES, 48(5), 968-975, 200305
- PDE5 inhibitor sildenafil citrate augments endothelium-dependent vasodilation in smokers, HYPERTENSION, 41(5), 1106-1110, 200305
- Smoking activates Rho-kinase in smooth muscle cells of forearm vasculature in humans, HYPERTENSION, 41(5), 1102-1105, 200305
- A comparison of low-dose and standard-dose oral estrogen on forearm endothelial function in early postmenopausal women, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 88(3), 1303-1309, 200303
- Choleretic action of diosgenin is based upon the increases in canalicular membrane fluidity and transporter activity mediating bile acid independent bile flow, HEPATOLOGY RESEARCH, 25(3), 287-295, 200303
- Giant gastric folds: Differential diagnosis at US, RADIOLOGY, 226(3), 686-690, 200303
- Screening of genes specifically activated in the pancreatic juice ductal cells from the patients with pancreatic ductal carcinoma, CANCER SCIENCE, 94(3), 263-270, 200303
- Unique reciprocal changes of hepatocellular membrane transporter expression and fluidity in rats with selective biliary obstruction, HEPATOLOGY RESEARCH, 26(2), 157-163, 200306
- Long-term observation of reflux oesophagitis developing after Helicobacter pylori eradication therapy, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 17(12), 1529-1534, 20030615
- Expression of hypoxia-inducible factor-l alpha is associated with tumor vascularization in human colorectal carcinoma, INTERNATIONAL JOURNAL OF CANCER, 105(2), 176-181, 20030610
- Inhibition of cholesterol crystallization under bilirubin deconjugation: partial characterization of mechanisms whereby infected bile accelerates pigment stone formation, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1632(1-2), 48-54, 20030610
- Expression of fibroblast growth factor receptor genes in human hepatoma-derived cell lines, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 39(7), 321-328, 2003
- Hypoxia-inducible factor-1 alpha expression and angiogenesis in gastrointestinal stromal tumor of the stomach, ONCOLOGY REPORTS, 10(4), 797-802, 2003
- Natural histories of hepatitis C virus infection in men and women simulated by the Markov model, JOURNAL OF MEDICAL VIROLOGY, 70(3), 378-386, 200307
- Cardiac angiotensin II type 2 receptor activates the kinin/NO system and inhibits fibrosis, HYPERTENSION, 41(1), 99-107, 200301
- Hydrophilic bile salts have a cytoprotective effect against cyclosporine A-induced cholestasis through enhanced canalicular membrane fluidity and transporter activity, HEPATOLOGY RESEARCH, 25(1), 38-47, 200301
- Autonomic nerve dysfunction is closely associated with the abnormalities of esophageal motility in reflux esophagitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(2), 159-163, 200302
- Helicobacter pylori infection influences tumor growth of human gastric carcinomas, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 38(2), 153-158, 200302
- Impaired gallbladder mucosal function in aged gallstone patients suppresses gallstone recurrence after successful extracorporeal shockwave lithotripsy, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 18(2), 157-161, 200302
- Leptin causes nitric-oxide independent coronary artery vasodilation in humans, HYPERTENSION RESEARCH, 26(2), 147-152, 200302
- Small rectal carcinoid with lymph node metastasis diagnosed prior to treatment, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 15(2), 195-197, 200302
- Promoter methylation of cyclin D2 gene in gastric carcinoma, INTERNATIONAL JOURNAL OF ONCOLOGY, 23(6), 1663-1670, 200312
- Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes, DIGESTIVE DISEASES AND SCIENCES, 48(12), 2315-2322, 200312
- Response of the left anterior descending coronary artery to Acetylcholine in patients with chest pain and angiographically normal coronary arteries, AMERICAN JOURNAL OF CARDIOLOGY, 92(12), 1394-1398, 20031215
- Mnk1 is required for angiotensin II - Induced protein synthesis in vascular smooth muscle cells, CIRCULATION RESEARCH, 93(12), 1218-1224, 20031212
- Myocardial bridging increases the risk of coronary spasm, CLINICAL CARDIOLOGY, 26(8), 377-383, 200308
- Somatic mutation of mitochondrial DNA in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 12(2), 169-174, 200308
- AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl4, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 308(1), 177-183, 20030815
- Comparison of forearm endothelial function between premenopausal and postmenopausal women with or without hypercholesterolemia, MATURITAS, 44(4), 307-315, 20030425
- Isolated granulomatous gastritis successfully treated by Helicobacter pylori eradication: a possible association between granulomatous gastritis and Helicobacter pylori, JOURNAL OF GASTROENTEROLOGY, 38(4), 371-375, 200304
- Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human gastric carcinomas, INTERNATIONAL JOURNAL OF ONCOLOGY, 22(4), 773-778, 200304
- Potential involvement of IL-8 and its receptors in the invasiveness of pancreatic cancer cells, INTERNATIONAL JOURNAL OF ONCOLOGY, 22(4), 765-771, 200304
- Serum pepsinogen concentration as a marker of Helicobacter pylori infection and the histologic grade of gastritis; evaluation of gastric mucosa by serum pepsinogen levels, JOURNAL OF GASTROENTEROLOGY, 38(4), 332-338, 200304
- Significance of an exaggerated meal-stimulated gastrin response in pathogenesis of Helicobacter pylori-negative duodenal ulcer, DIGESTIVE DISEASES AND SCIENCES, 48(4), 644-651, 200304
- Depressed-type, early duodenal carcinoma(carcinoma in situ) treated by endoscopic mucosal resection, J. Gastroenterol., 38(8), 813-815, 20030401
- Expression of hyposia-inducible factor-1 alpha is associated with tumor vascularization in human colorectal carcinoma, Int J Cancer, 105(2), 176-181, 20030401
- Expression of vascular endothelial growth facter and angiogenesis in gastrointestinal stromal tumor of the stomach, Oncology, 64(3), 266-274, 20030401
- Minute depressed colon cancer with submucosal invasion, Gastrointest Endosc, 57(4), 564-565, 20030401
- Nondular gastritis in adults is caused by Helicobacter pylori ingfection, Dig Dis Sci, 48(5), 968-975, 20030401
- Prominent J wave and ST segment elevation: Serial electrocardiographic changes in accidental hypothermia, Journal of cardiovasuclar electrophysiology, 14(2), 223, 20030401
- Clinical significance of angiogenic factor expression at the deepest invasive site of advanced colorectal carcinoma, ONCOLOGY, 64(1), 61-73, 2003
- Expression of vascular endothelial growth factor and angiogenesis in gastrointestinal stromal tumor of the stomach, ONCOLOGY, 64(3), 266-274, 2003
- Rare quasispecies in the YMDD motif of hepatitis B virus detected by polymerase chain reaction with peptide nucleic acid clamping, INTERVIROLOGY, 46(6), 355-361, 2003
- Combination therapy of low-dose medroxyprogesterone acetate and oral estrogen does not affect endothelial function in the forearms of postmenopausal women, MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 9(5), 360-366, 2002
- Determining depth of invasion by VN pit pattern analysis in submucosal colorectal carcinoma, ONCOLOGY REPORTS, 9(5), 1005-1008, 2002
- Clinical characteristics and natural history of patients with low-grade reflux esophagitis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 17(9), 949-954, 200209
- Combination of transcatheter arterial chemoembolization using cisplatin-lipiodol suspension and percutaneous ethanol injection for treatment of advanced small hepatocellular carcinoma, AMERICAN JOURNAL OF SURGERY, 184(3), 284-290, 200209
- Nicorandil-induced preconditioning as evidenced by troponin T measurements after coronary angioplasty in patients with stable angina pectoris, JAPANESE HEART JOURNAL, 43(5), 443-453, 200209
- Hormone replacement effects on endothelial function measured in the forearm resistance artery in normocholesterolemic and hypercholesterolemic postmenopausal women, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 87(10), 4634-4641, 200210
- Human telomerase reverse transcriptase, p53 and Ki-67 expression and apoptosis in colorectal serrated adenoma, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(10), 1194-1200, 200210
- Effect of alcohol consumption on endothelial function in men with coronary artery disease, ATHEROSCLEROSIS, 165(1), 145-152, 200211
- Irsogladine malate up-regulates gap junctional intercellular communication between pancreatic cancer cells via PKA pathway, PANCREAS, 25(4), 373-377, 200211
- Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human esophageal squamous cell carcinomas, INTERNATIONAL JOURNAL OF CANCER, 102(3), 220-224, 20021120
- Clinical significance of angiogenesis in rectal carcinoid tumors, ONCOLOGY REPORTS, 9(3), 489-494, 2002
- Balloon-occluded retrograde transvenous obliteration of gastric fundal varices with hemorrhage, AMERICAN JOURNAL OF ROENTGENOLOGY, 178(5), 1167-1174, 200205
- Implication of anti-parietal cell antibody levels in gastrointestinal diseases, including gastric carcinogenesis, DIGESTIVE DISEASES AND SCIENCES, 47(5), 1080-1085, 200205
- Preoperative assessment of gastric cancer vascularity by flash echo imaging, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(5), 608-612, 200205
- Severity of hypertension affects improved resistance artery endothelial function by angiotensin-converting enzyme inhibition, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 39(5), 668-676, 200205
- Cigarette smoking promotes atrophic gastritis in Helicobacter pylori-positive subjects, DIGESTIVE DISEASES AND SCIENCES, 47(3), 675-681, 200203
- Leptin causes vasodilation in humans, HYPERTENSION RESEARCH, 25(2), 161-165, 200203
- Role of anti-parietal cell antibody in Helicobacter pylori-associated atrophic gastritis: Evaluation in a country of high prevalence of atrophic gastritis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(3), 287-293, 200203
- Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia, HEART, 87(3), 264-269, 200203
- Management of chronic hepatitis C and prevention of hepatocellular carcinoma, JOURNAL OF GASTROENTEROLOGY, 37, 69-73, 200206
- ★, Endothelial function and oxidative stress in renovascular hypertension, NEW ENGLAND JOURNAL OF MEDICINE, 346(25), 1954-1962, 20020620
- Evaluation of esophageal motility by endosonography using a miniature ultrasonographic probe in patients with reflux esophagitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(6), 674-678, 20020601
- Evaluation of gastric emptying measured with the C-13-octanoic acid breath test in patients with functional dyspepsia comparison with ultrasonography, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(6), 662-666, 20020601
- Preconditioning effect during coronary angioplasty in patients with stable angina pectoris, INTERNAL MEDICINE, 41(7), 509-515, 200207
- Renal endothelial dysfunction and hypertension, JOURNAL OF DIABETES AND ITS COMPLICATIONS, 16(1), 103-107, 2002
- Tetrahydrobiopterin improves coronary endothelial function, but does not prevent coronary spasm in patients with vasospastic angina, CIRCULATION JOURNAL, 66(1), 58-62, 200201
- Excess norepinephrine impairs both endothelium-dependent and -independent vasodilation in patients with pheochromocytoma, HYPERTENSION, 39(2), 513-518, 200202
- Helicobacter pylori infection increases serum nitrate and nitrite more prominently than serum pepsinogens, HELICOBACTER, 7(1), 9-13, 200202
- Serological comparison of serum pepsinogen and antiparietal cell antibody levels between Japanese and German patients, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 14(2), 123-127, 200202
- Estrogen replacement suppresses function of thrombin stimulated platelets by inhibiting Ca2+ influx and raising cyclic adenosine monophosphate, CARDIOVASCULAR RESEARCH, 53(3), 634-641, 20020215
- Less hydrophobic phosphatidylcholine species simplify biliary vesicle morphology, but induce bile metastability with a broad spectrum of crystal forms, BIOCHEMICAL JOURNAL, 362, 105-112, 20020215
- K-ras mutation in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer, INTERNATIONAL JOURNAL OF CANCER, 97(5), 562-566, 20020210
- Circadian variation of blood pressure and endothelial function in patients with essential hypertension: A comparison of dippers and non-dippers, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 40(11), 2039-2043, 20021204
- A frameshift mutation of beta subunit of epithelial sodium channel in a case of isolated Liddle syndrome, JOURNAL OF HYPERTENSION, 20(12), 2379-2382, 200212
- Mechanisms responsible for vasodilation upon magnesium infusion in vivo: Clinical evidence, MAGNESIUM RESEARCH, 15(3-4), 241-246, 200212
- Advanced colorectal carcinoma smaller than 10 mm in maximum diameter with special reference to clinicopathologic and molecular features: a report of 3 cases, GASTROINTESTINAL ENDOSCOPY, 56(2), 299-303, 200208
- Helicobacter pylori eradication therapy improves atrophic gastritis and intestinal metaplasia: a 5-year prospective study of patients with atrophic gastritis, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 16(8), 1449-1456, 200208
- A low-calorie diet improves endothelium-dependent vasodilation in obese patients with essential hypertension, AMERICAN JOURNAL OF HYPERTENSION, 15(4), 302-309, 200204
- High incidence of B-cell monoclonality in follicular gastritis: a possible association between follicular gastritis and MALT lymphoma, VIRCHOWS ARCHIV, 440(4), 376-380, 200204
- Long-term rebamipide therapy improves Helicobacter pylori-associated chronic gastritis, DIGESTIVE DISEASES AND SCIENCES, 47(4), 862-867, 200204
- Nicorandil enhances myocardial tolerance to ischemia without progressive collateral recruitment during coronary angioplasty, CIRCULATION JOURNAL, 66(4), 317-322, 200204
- Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals, AMERICAN JOURNAL OF HYPERTENSION, 15(4), 326-332, 200204
- Hepatic hydroxylation of bile acids and chronic liver diseases: do transporters play a mechanistic role?, 20020401
- Single administration of ecabet sodium diminishes the level of delta-(13) Co(2) in urea breath test, J GastroenterolM., 37(8), 674-675, 20020401
- Clinical significance of vascular endothelial growth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma, ONCOLOGY, 62(2), 157-166, 2002
- Pathogenic significance and organic virus levels in patients infected with TT virus, INTERVIROLOGY, 44(5), 291-297, 2001
- A low C-13-urea breath test value is associated with increased risk of gastric cancer, JOURNAL OF GASTROENTEROLOGY, 36(9), 601-605, 200109
- Expression of telomeric repeat binding factor 1 and 2 and TRF1-interacting nuclear protein 2 in human gastric carcinomas, INTERNATIONAL JOURNAL OF ONCOLOGY, 19(3), 507-512, 200109
- Randomized controlled clinical trial of lymphoblastoid interferon-alpha for chronic hepatitis C, HEPATOLOGY RESEARCH, 21(1), 55-66, 200109
- Clinicopathological significance of vascular endothelial growth factor (VEGF)-C in human esophageal squamous cell carcinomas, INTERNATIONAL JOURNAL OF CANCER, 93(5), 662-666, 20010901
- Calorie restriction reduced blood pressure in obesity hypertensives by improvement of autonomic nerve activity and insulin sensitivity, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 38, S69-S74, 200110
- Effect of obesity on endothelium-dependent, nitric oxide-mediated vasodilation in normotensive individuals and patients with essential hypertension, AMERICAN JOURNAL OF HYPERTENSION, 14(10), 1038-1045, 200110
- MUC1 and cathepsin D expression in early colorectal carcinoma showing V type pit pattern, INTERNATIONAL JOURNAL OF ONCOLOGY, 19(4), 665-672, 200110
- Extracorporeal ultrasound is an effective diagnostic alternative to endoscopic ultrasound for gastric submucosal tumours, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 36(11), 1222-1226, 200111
- Sodium chloride loading does not alter endothelium-dependent vasodilation of forearm vasculature in either salt-sensitive or salt-resistant patients with essential hypertension, HYPERTENSION RESEARCH, 24(6), 711-716, 200111
- Microsatellite instability is a genetic marker for the development of multiple gastric cancers, INTERNATIONAL JOURNAL OF CANCER, 95(6), 350-353, 20011120
- Usefulness of flow-mediated dilation of the brachial artery and/or the intima-media thickness of the carotid artery in predicting coronary narrowing in patients suspected of having coronary artery disease, AMERICAN JOURNAL OF CARDIOLOGY, 88(10), 1147-1151, 20011115
- Bile-salt hydrophobicity is a key factor regulating rat liver plasma-membrane communication: relation to bilayer structure, fluidity and transporter expression and function, BIOCHEMICAL JOURNAL, 359, 605-610, 20011101
- Reduction in the incidence of Helicobacter pylori-associated carcinoma in Japanese young adults, ONCOLOGY REPORTS, 8(3), 633-636, 2001
- Is a role of phospholipase A(2) in cholesterol gallstone formation phospholipid species-dependent?, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1532(1-2), 51-59, 20010531
- Non-dipper phenomenon in essential hypertension is related to blunted nocturnal rise and fall of sympatho-vagal nervous activity and progress in retinopathy, AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, 88(3), 181-186, 20010514
- c-myc gene mutation in gastric mucose-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphoma, ONCOLOGY REPORTS, 8(2), 289-292, 2001
- Microsatellite instability at D18S61 is associated with no regression of gastric mucosa-associated lymphoid tissue lymphoma after Helicobacter pylori eradication, ONCOLOGY REPORTS, 8(2), 293-297, 2001
- Cyclosporin A reduces canalicular membrane fluidity and regulates transporter function in rats, BIOCHEMICAL JOURNAL, 354, 591-596, 20010315
- Dose-dependent conjugation of sulfobromophthalein and hepatic transit time in bile fistula rats - Role of the microtubule-dependent vesicle pathway, DIGESTIVE DISEASES AND SCIENCES, 46(6), 1285-1289, 200106
- Evaluation of quantitative measurements of hepatitis C virus RNA to predict sustained response to interferon by genotype, JOURNAL OF VIROLOGICAL METHODS, 95(1-2), 33-45, 200106
- Helicobacter pylori eradication therapy for high-grade mucosa-associated lymphoid tissue lymphomas of the stomach with analysis of p53 and K-ras alteration and microsatellite instability, INTERNATIONAL JOURNAL OF ONCOLOGY, 18(6), 1207-1212, 200106
- Risk factors of hepatitis C virus-related liver cirrhosis in young adults: Positive family history of liver disease and transporter associated with antigen processing 2 (TAP2)*0201 allele, JOURNAL OF MEDICAL VIROLOGY, 64(2), 109-116, 200106
- Clinicopathologic features and endoscopic treatment of superficially spreading colorectal neoplasms larger than 20 mm, GASTROINTESTINAL ENDOSCOPY, 54(1), 62-66, 200107
- Clinicopathological features of gastric mucosa-associated lymphoid tissue lymphoma: A comparison with diffuse large B-cell lymphoma without a mucosa-associated lymphoid tissue lymphoma component, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 16(7), 734-739, 200107
- Effect of estrogen replacement therapy on endothelial function in peripheral resistance arteries in normotensive and hypertensive postmenopausal women, HYPERTENSION, 37(2), 651-657, 200102
- Lamivudine therapy for spontaneously occurring severe acute exacerbation in chronic hepatitis B virus infection: A preliminary study, AMERICAN JOURNAL OF GASTROENTEROLOGY, 96(2), 557-562, 200102
- Does bilirubin play a role in the pathogenesis of both cholesterol and pigment gallstone formation? Direct and indirect influences of bilirubin on bile lithogenicity, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1534(2-3), 78-84, 20011230
- Endothelial dysfunction is an independent factor responsible for vasospastic angina, CLINICAL SCIENCE, 101(6), 707-713, 200112
- Interleukin 8 and vascular endothelial growth factor - prognostic factors in human gastric carcinomas?, EUROPEAN JOURNAL OF CANCER, 37(12), 1482-1487, 200108
- Nonselective cation channel as a Ca2+ influx pathway in pepsinogen-secreting cells of bullfrog esophagus, AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 281(2), G333-G341, 200108
- Angiotensin II type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin II type 1 receptor antagonist, FEBS LETTERS, 495(3), 197-200, 20010427
- Angiotensin (]G0002[) type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin (]G0002[) type 1 receptor antagonist, FEBS Lett, 495, 197-200, 20010401
- Diagnosis of invasion depth in early colorectal carcinoma by pit pattern analysis with magnifying endoscopy, Digestive Endoscopy, 13, S2-S5, 20010401
- Effect of for antihypertensives on reactive hypermia in essential hypertension, Cardiology Review, 18(4), 31-39, 20010401
- Efficacy of IFN therapy based on duration period of negative HCV-RNA during IFN administration, Hepatol Res, 19, 22-300, 20010401
- Long-term interferon therapy for 1 year or longer reduces the hepatocellular carcinogenesis rate in patients with liver cirrhosis caused by hepatitis C virus: a pilot study, J Gastroenterol Hepatol., 16(4), 406-415, 20010401
- Risk factors of hepatitis C virus-related liver cirrhosis in young adults: positive family history of liver disease and transporter associated with antigen processing 2(TAP2)*0201 Allele., J Med Virol, 64, 109-116, 20010401
- Twice-daily administration of interferon-beta for chronic hepatitis C is not superior to a once-daily regimen, J. Gastroenterol, 36, 242-247, 20010401
- Activation of peroxisome proliferator-activated receptor gamma inhibits the growth of human pancreatic cancer, PATHOBIOLOGY, 69(5), 258-265, 2001
- Expression of MRE11 complex (MRE11, RAD50, NBS1) and hRap1 and its relation with telomere regulation, telomerase activity in human gastric carcinomas, PATHOBIOLOGY, 69(4), 219-224, 2001
- Association of amino acid sequence in the PKR-eIF2 phosphorylation homology domain and response to interferon therapy, HEPATOLOGY, 32(5), 1138-1144, 200011
- Distinction between chronic hepatitis and liver cirrhosis in patients with hepatitis C virus infection. Practical discriminant function using common laboratory data, Hepatol Res, 18(3), 252-266, 20000401
- Fluctuation patterns of HCV-RNA serum level in patients with chronic hepatitis C, J. Gastroenterol., 35(3), 221-225, 20000401
- Incidence of primary liver cancer-cholangiocellular type in Japanese patients with hepatitis C virus related cirrhosis, Cancer, 88, 2471-2477, 20000401
- Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor-A prospective randomized study of hepatitis C virus-related liver cancer., Hepatology, 32(2), 436-438, 20000401
- Progressive and sufficient decrease of hepatitis B core antibody can predict the disappearance of hepatitis B virus DNA in Japanese patients with hepatitis B surface antigen clearance, J. Gastroenterol., 35(10), 753-757, 20000401
- Relationship between five-year histological outcome and serial changes in serum alanine aminotransferase in patients with biochemical and virological relapse after interferon treatment for chronic hepatitis C, Intervirol, 43, 174-179, 20000401
- A device for simultaneous application of sclerotherapy and endoscopic ligation for management of esophageal varices, Dig.Endosc, 11, 363-365, 19990401
- Chronic liver disease in the extremely elderly of 80 years or more: clinical characteristics, prognosis and patient survival analysis, J Hepatol, 31, 860-866, 19990401
- Clinical and virological features of chronic hepatitis C carriers with normal alanine aminotransferase levels despite positive serum HCV-RNA after interferon therapy, J. Gastroenterol., 34, 594-599, 19990401
- Combined ursodeoxycholic acid glycyrrhizin therapy for chronic hepatitis C virus infection: a randomized controlled trial in 170 patients, Eur J Gastroen Hepat, 11, 1077-1083, 19990401
- Effect of arterial administration of a high-molecular weight antitumor agent,styrene maleic acid neocarzinostatin,in embolization-resistant liver cancer, Int. J. Clin. Oncol., 14, 148-155, 19990401
- Effect of interferon therapy on hepatocellular carcinogenesis in patients with chronic hepatitis type C: A long-term observation study of 1,643 patients using statistical bias correction with proportional hazard analysis, Hepatology, 29(4), 1124-1130, 19990401
- Efficacy and changes of the nonstructural 5A gene by prolonged interferon therapy for patients with hepatitis C virus (HCV) genotype1b and a high level of serum HCV-RNA, Intern Med, 38, 19990401
- Enzyme-linked immunosorbent assay to detect hepatitis C virus serological groups 1to 6, J. Gastroenterol., 34, 505-509, 19990401
- Fluctuations of hepatitis C virus load are not related to amino acid substitutions in hypervariable region 1 and interferon sensitivity determining region, J Med Virol, 58, 247-255, 19990401
- Histological changes in liver biopsies after one year of lamivudine treatment in patients with chronic hepatitis B infection, J Hepatol, 30, 743-748, 19990401
- Prevalence of TT virus before and after blood transfusion in patients with chronic liver disease treated surgically for hepatocellular carcinoma, J Gastroenterol Hepatol., 14, 358-363, 19990401
- Susceptibility of TT virus to interferon therapy, J. Gen. Virol., 80, 631-634, 19990401
- Time course of histological changes in patients with a sustained biochemical and virological response to corticosteroid withdrawal therapy for chronic hepatitis B, Am J Gastroenterol, 94, 3304-3309, 19990401
- A randomized controlled trial of interferon-alpha in patients with cirrhosis caused by 2a/2b genotype hepatitis C virus, J Hepatol, 27(5), 910-912, 19980401
- Biochemical and histological features of hepatitis G virus infection, J Gastroenterol Hepatol., 13, 767-772, 19980401
- Deletions in the hepatitis B virus core gene may influence the clinical outcome in hepatitis B e antigen-positive asymptomatic healthy carriers., Journal of Medical Virology, 56, 287-293, 19980401
- Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients, J Hepatol, 28, 930-938, 19980401
- Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy., Hepatology, 27, 1711-1716, 19980401
- Glomerulonephritis in autopsy cases with hepatitis C virus infection, Internal Med., 37(10), 836-840, 19980401
- Interferon decreases hepatocellular carcinogenesis in patients with cirrhosis caused by the hepatitis B virus-A pilot study, Cancer, 82(5), 827-835, 19980401
- Predictive factors in eradicating hepatitis C virus using a relatively small dose of interferon, J Gastroenterol Hepatol., 13, 412-418, 19980401
- Relationship of angiographic finding with neovascular structure detected by immunohistochemical staining of alpha-smooth muscle action in small hepatocellular carcinoma, J Gastroenterol Hepatol., 13, 1266-1273, 19980401
- Relationship of hepatocellular carcinogenesis with precore mutant virus and serum hepatitis B virus DNA concentration. A longitudinal analysis of patients with cirrhosis, Hepatol Res, 10, 142-155, 19980401
- Usefulness of hepatitis C virus RNA counts by second generation HCV bDNA-probe in chronic hepatitis C based on the HCV genotype, J. Gastroenterol., 33(2), 223-228, 19980401
- A prospective randomized administration of 5'-deoxy-5-fluorouridine as adjuvant chemotherapy for hepatocellular carcinoma treated with transcatheter arterial chemoembolization., Am. J. Clin. Oncol., 20(2), 202-208, 19970401
- Effect of arterial administration of a high molecular weight anti-tumor agent, styrene maleic acid neocarzinostain, for multiple small liver cancer-A pilot study, J. Gastroenterol., 32, 513-520, 19970401
- Effect of interferon therapy on viral titers in patients with chronic hepatitis C who are positive for hepatitis GB virus C, J Hepatol, 26, 769-770, 19970401
- Hepatitis G virus infection after blood transfusion in patients with chronic liver disease treated surgically for hepatocellular carcinoma, Hepatol Res, 9(1), 28-36, 19970401
- Nucleotide sequences of hepatitis GB virus C. Identification of highly conserved domains in the 5' noncoding region and detection by polymerase chain reaction, Int Hepatol Commun, 6, 225-232, 19970401
- Pretreatment virus load and multiple amino acid substitutions in the interferon sensitivity-determining region predict the outcome of interferon treatment in patients with chronic genotype 1b hepatitis C virus infection, Hepatology, 25, 745-749, 19970401
- The long term efficacy of glycyrrhizin in chronic hepatitis C patients, Cancer, 79(8), 1494-1500, 19970401
- The superiority of laparoscopic examination in predicting hepatocellular carcinoma after interferon therapy for chronic type C hepatitis, Dig.Endosc, 9(1), 29-33, 19970401
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- mTOR and PDGF Pathway Blockade Inhibits Liver Metastasis of Colorectal Cancer by Modulating the Tumor Microenvironment, AMERICAN JOURNAL OF PATHOLOGY, 185(2), 399-408, 2015
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- Differences in serum microRNA profiles in hepatitis B and C virus infection, JOURNAL OF INFECTION, 70(3), 273-287, 2015
- Combining molecular targeted drugs to inhibit both cancer cells and activated stromal cells in colon cancer, CANCER RESEARCH, 74(19), 2014
- Interaction between bone marrow-derived mesenchymal stem cells and tumor cells induces expression of fibronectin in human colon cancer cells, CANCER RESEARCH, 74(19), 2014
- The effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(3), 619-627, 2015
- Emerging treatments for chronic hepatitis C, JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 114(3), 204-215, 2015
- Rate of Unintended Helicobacter pylori Eradication in the Vietnamese, HELICOBACTER, 20(2), 156-157, 2015
- Evaluation of early response to hepatic arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma using the combination of Response Evaluation Criteria in Solid Tumors and tumor markers, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(4), 726-732, 2015
- Risk factors and management of positive horizontal margin in early gastric cancer resected by en bloc endoscopic submucosal dissection, GASTRIC CANCER, 18(2), 332-338, 2015
- Evaluation of Antibiotic Use to Prevent Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis and Cholangitis, HEPATO-GASTROENTEROLOGY, 62(138), 417-424, 2015
- Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection, SCIENCE TRANSLATIONAL MEDICINE, 7(282), 2015
- Stereotactic body radiotherapy for patients with small hepatocellular carcinoma ineligible for resection or ablation therapies, HEPATOLOGY RESEARCH, 45(4), 378-386, 2015
- Randomized Trial of Interferon- and Ribavirin-Free Ombitasvir/Paritaprevir/Ritonavir in Treatment-Experienced Hepatitis C Virus-Infected Patients, HEPATOLOGY, 61(5), 1523-1532, 2015
- Eicosapentaenoic acid/arachidonic acid ratio as a possible link between non-alcoholic fatty liver disease and cardiovascular disease, HEPATOLOGY RESEARCH, 45(5), 533-539, 2015
- Novel Robust in Vitro Hepatitis B Virus Infection Model Using Fresh Human Hepatocytes Isolated from Humanized Mice, AMERICAN JOURNAL OF PATHOLOGY, 185(5), 1275-1285, 2015
- Role of 3-D conformal radiotherapy for major portal vein tumor thrombosis combined with hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma, HEPATOLOGY RESEARCH, 45(6), 607-617, 2015
- Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis, HEPATOLOGY RESEARCH, 45(6), 656-662, 2015
- Disseminated carcinomatosis of the bone marrow originating from hepatocellular carcinoma. A case report, HEPATOLOGY RESEARCH, 45(6), 705-710, 2015
- The Time Course of Dynamic Computed Tomographic Appearance of Radiation Injury to the Cirrhotic Liver Following Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma, PLOS ONE, 10(6), 2015
- Rapid, Sensitive, and Accurate Evaluation of Drug Resistant Mutant (NS5A-Y93H) Strain Frequency in Genotype 1b HCV by Invader Assay, PLOS ONE, 10(6), 2015
- ADIPOQ polymorphisms are associated with insulin resistance in Japanese women, ENDOCRINE JOURNAL, 62(6), 513-521, 2015
- Efficacy of radiofrequency ablation for initial recurrent hepatocellular carcinoma after curative treatment: Comparison with primary cases, EUROPEAN JOURNAL OF RADIOLOGY, 84(8), 1540-1545, 2015
- IL-1 beta/ATF3-mediated induction of Ski2 expression enhances hepatitis B virus x mRNA degradation, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 503(3), 1854-1860, 20180910
- Chromosome 4q25 Variant rs6817105 Bring Sinus Node Dysfunction and Left Atrial Enlargement, SCIENTIFIC REPORTS, 8, 20181001
- Chromosomal Abnormalities in Human Lymphocytes after Computed Tomography Scan Procedure, RADIATION RESEARCH, 190(4), 424-432, 201810
- Comparison of Stereotactic Body Radiation Therapy Combined With or Without Transcatheter Arterial Chemoembolization for Patients With Small Hepatocellular Carcinoma Ineligible for Resection or Ablation Therapies, TECHNOLOGY IN CANCER RESEARCH & TREATMENT, 17, 20180701
- HCN4 Gene Polymorphisms Are Associated With Occurrence of Tachycardia-Induced Cardiomyopathy in Patients With Atrial Fibrillation, CIRCULATION-GENOMIC AND PRECISION MEDICINE, 11(7), 201807
- Advanced liver fibrosis effects on the response to sofosbuvir-based antiviral therapies for chronic hepatitis C, JOURNAL OF MEDICAL VIROLOGY, 90(12), 1834-1840, 201812
- The novel cutoff points for the FIB4 index categorized by age increase the diagnostic accuracy in NAFLD: a multi-center study, JOURNAL OF GASTROENTEROLOGY, 53(11), 1216-1224, 201811
- Molecular Mechanisms of Hepatocarcinogenesis Following Sustained Virological Response in Patients with Chronic Hepatitis C Virus Infection, VIRUSES-BASEL, 10(10), 201810
- Early experience of seven hepatocellular carcinoma cases treated with regorafenib, CLINICAL CASE REPORTS, 6(11), 2217-2223, 201811
- Diagnosis of superficial esophageal squamous cell carcinoma invasion depth before endoscopic submucosal dissection, DISEASES OF THE ESOPHAGUS, 31(7), 201807
- Magnifying Endoscopy with Narrow Band Imaging in Estimating the Invasion Depth of Superficial Esophageal Squamous Cell Carcinomas, DIGESTION, 98(4), 249-256, 2018
- CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic hepatitis B patients, JOURNAL OF VIRAL HEPATITIS, 25(12), 1555-1564, 201812
- Endothelial Dysfunction, Increased Arterial Stiffness, and Cardiovascular Risk Prediction in Patients With Coronary Artery Disease: FMD-J (Flow-Mediated Dilation Japan) Study A, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 7(14), 20180717
- Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes, VIROLOGY, 525, 48-61, 201812
- Range of Normal Liver Stiffness and Factors Associated With Increased Stiffness Measurements in Apparently Healthy Individuals, CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 17(1), 54-+, 201901
- Comparison of hepatic arterial infusion chemotherapy between 5-fluorouracil-based continuous infusion chemotherapy and low-dose cisplatin monotherapy for advanced hepatocellular carcinoma, HEPATOLOGY RESEARCH, 48(13), 1118-1130, 201812
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- The association between serum cytokine and chemokine levels and antiviral response by entecavir treatment in chronic hepatitis B patients, ANTIVIRAL THERAPY, 23(3), 239-248, 2018
- Dual Red Imaging Maintains Clear Visibility During Colorectal Endoscopic Submucosal Dissection, DIGESTIVE DISEASES AND SCIENCES, 64(1), 224-231, 201901
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- Gastric Cancer with Submucosal Invasion after Successful Helicobacter pylori Eradication: A Propensity Score-Matched Analysis of Patients with Annual Patient Endoscopic Survey, DIGESTION, 99(1), 59-65, 2019
- The utility of a novel colonoscope with retroflexion for colorectal endoscopic submucosal dissection, ENDOSCOPY INTERNATIONAL OPEN, 7(2), E130-E137, 201902
- The impact of interferon-free direct-acting antivirals on clinical outcome after curative treatment for hepatitis C virus-associated hepatocellular carcinoma: Comparison with interferon-based therapy, JOURNAL OF MEDICAL VIROLOGY, 91(4), 650-658, 201904
- Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor, PLOS ONE, 14(2), 20190219
- Early-stage serrated adenocarcinomas are divided into several molecularly distinct subtypes, PLOS ONE, 14(2), 20190220
- Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures, JOURNAL OF GASTROENTEROLOGY, 54(3), 291-296, 201903
- Levocarnitine Use Is Associated With Improvement in Sarcopenia in Patients With Liver Cirrhosis, HEPATOLOGY COMMUNICATIONS, 3(3), 348-355, 201903
- Rectal Lymphoid Follicle Aphthous Lesions Frequently Progress to Ulcerative Colitis with Proximal Extension, INTERNAL MEDICINE, 58(5), 625-631, 201903
- Ser96Ala genetic variant of the human histidine-rich calcium-binding protein is a genetic predictor of recurrence after catheter ablation in patients with paroxysmal atrial fibrillation, PLOS ONE, 14(3), 20190306
- Epidemiological survey of hemoglobin A1c and liver fibrosis in a general population with non-alcoholic fatty liver disease, HEPATOLOGY RESEARCH, 49(3), 296-303, 201903
- Construction of a risk model for the development of metachronous squamous cell carcinoma after endoscopic resection of esopahageal squamous cell carcinoma, ESOPHAGUS, 16(2), 141-146, 201904
- A nationwide survey on non-B, non-C hepatocellular carcinoma in Japan: 2011-2015 update, JOURNAL OF GASTROENTEROLOGY, 54(4), 367-376, 201904
- Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: a pilot study, ANTIVIRAL THERAPY, 23(8), 639-646, 2018
- Long-term prognosis after treatment for T1 carcinoma of laterally spreading tumors: a multicenter retrospective study, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 34(3), 481-490, 201903
- Early Multiphasic HBV Infection Initiation Kinetics Is Not Clone-Specific and Is Not Affected by Hepatitis D Virus (HDV) Infection, VIRUSES-BASEL, 11(3), 20190315
- Coffee with a high content of chlorogenic acids and low content of hydroxyhydroquinone improves postprandial endothelial dysfunction in patients with borderline and stage 1 hypertension, EUROPEAN JOURNAL OF NUTRITION, 58(3), 989-996, 201904
- Rapid and persistent decline in soluble CD163 with successful direct-acting antiviral therapy and associations with chronic hepatitis C histology, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 53(8), 986-993, 2018
- Target of Triglycerides as Residual Risk for Cardiovascular Events in Patients With Coronary Artery Disease - Post Hoc Analysis of the FMD-J Study A, CIRCULATION JOURNAL, 83(5), 1064-+, 201905
- The Clinical Usefulness of the PillCam Progress Indicator for Route Selection in Double Balloon Endoscopy, INTERNAL MEDICINE, 58(10), 1375-1381, 2019
- HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response, GASTROENTEROLOGY, 156(8), 2313-+, 201906
- Alpha-fetoprotein and des-gamma-carboxy-prothrombin at twenty-four weeks after interferon-based therapy predict hepatocellular carcinoma development, WORLD JOURNAL OF HEPATOLOGY, 7(27), 2757-2764, 20151128
- Circulating Tumor DNA Analysis for Liver Cancers and Its Usefulness as a Liquid Biopsy, CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 1(5), 516-534, 201509
- Use of Mac-2 Binding Protein as a Biomarker for Nonalcoholic Fatty Liver Disease Diagnosis, HEPATOLOGY COMMUNICATIONS, 1(8), 780-791, 201710
- Experience with Balloon Dilatation in Crohn's and Non-Crohn's Benign Small-Bowel Strictures: Is There a Difference?, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2019
- Impact of sclerosing dacryoadenitis/sialadenitis on relapse during steroid therapy in patients with type 1 autoimmune pancreatitis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 54(2), 259-264, 20190201
- Impact of controlled attenuation parameter on detecting fibrosis using liver stiffness measurement, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 47(7), 989-1000, 201804
- Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes, CANCER CELL, 35(6), 932-+, 20190610
- Regulation of the Hepatitis B virus replication and gene expression by the multi-functional protein TARDBP, SCIENTIFIC REPORTS, 9, 20190611
- Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis, JOURNAL OF BIOMEDICAL SCIENCE, 26, 20190606
- Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice, JOURNAL OF GASTROENTEROLOGY, 54(7), 650-659, 201907
- Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study, JOURNAL OF HYPERTENSION, 37(5), 1083-1095, 201905
- Effect of Saxagliptin on Endothelial Function in Patients with Type 2 Diabetes: A Prospective Multicenter Study, SCIENTIFIC REPORTS, 9, 20190715
- Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice, JOURNAL OF GENERAL VIROLOGY, 100(7), 1123-1131, 201907
- Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of Hepatitis C Virus-Infected Cells and Liver to Identify Pathways Associated With Disease Development, GASTROENTEROLOGY, 157(2), 537-+, 201908
- Real-world virological efficacy and safety of daclatasvir/asunaprevir/beclabuvir in patients with chronic hepatitis C virus genotype 1 infection in Japan, JOURNAL OF GASTROENTEROLOGY, 54(8), 742-751, 201908
- y Integrated analysis of 8-week glecaprevir/pibrentasvir in Japanese and overseas patients without cirrhosis and with hepatitis C virus genotype 1 or 2 infection, JOURNAL OF GASTROENTEROLOGY, 54(8), 752-761, 201908
- Can surveillance colonoscopy be discontinued in an elderly population with diminutive polyps?, JOURNAL OF THE ANUS RECTUM AND COLON, 3(3), 128-135, 201907
- Helicobacter suis infection is associated with nodular gastritis-like appearance of gastric mucosa-associated lymphoid tissue lymphoma, CANCER MEDICINE, 8(9), 4370-4379, 201908
- Relationship between home blood pressure and vascular function in patients receiving antihypertensive drug treatment, HYPERTENSION RESEARCH, 42(8), 1175-1185, 201908
- Percutaneous transvenous shunt occlusion for portosystemic encephalopathy due to lenvatinib administration to a patient with hepatocellular carcinoma and portosystemic shunt, CLINICAL JOURNAL OF GASTROENTEROLOGY, 12(4), 341-346, 201908
- Correlation between Early Tumor Marker Response and Imaging Response in Patients with Advanced Hepatocellular Carcinoma Treated with Lenvatinib, ONCOLOGY, 97(2), 75-81, 2019
- Management of HCV patients in cases of direct-acting antiviral failure, EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 13(9), 839-848, 20190902
- Early changes in ammonia levels and liver function in patients with advanced hepatocellular carcinoma treated by lenvatinib therapy, SCIENTIFIC REPORTS, 9, 20190820
- Alcohol Use Disorders Identification Test-consumption Predicts the Risk of Excessive Alcohol Consumption After Liver Transplantation, TRANSPLANTATION PROCEEDINGS, 51(6), 1934-1938, 2019
- HOMA-IR: An independent predictor of advanced liver fibrosis in nondiabetic non-alcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 34(8), 1390-1395, 201908
- Preceding endoscopic submucosal dissection for T1 colorectal carcinoma does not affect the prognosis of patients who underwent additional surgery: a large multicenter propensity score-matched analysis, JOURNAL OF GASTROENTEROLOGY, 54(10), 897-906, 201910
- Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy, JOURNAL OF GASTROENTEROLOGY, 54(10), 907-915, 201910
- Clinical features of hepatocellular carcinoma in nonalcoholic fatty liver disease patients without advanced fibrosis, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 34(9), 1626-1632, 201909
- Relationships Between Calcium Channel Blockers and Vascular Function Tests, AMERICAN JOURNAL OF HYPERTENSION, 32(7), 640-648, 201907
- Effects of the Dipeptidyl Peptidase 4 Inhibitor Alogliptin on Blood Pressure in Hypertensive Patients with Type 2 Diabetes Mellitus, AMERICAN JOURNAL OF HYPERTENSION, 32(7), 695-702, 201907
- Association of extremely high levels of high-density lipoprotein cholesterol with endothelial dysfunction in men, JOURNAL OF CLINICAL LIPIDOLOGY, 13(4), 664-672, 201908
- eVIDENCE: a practical variant filtering for low-frequency variants detection in cell-free DNA, SCIENTIFIC REPORTS, 9, 20191022
- Pruritus in patients with chronic liver disease and serum autotaxin levels in patients with primary biliary cholangitis, BMC GASTROENTEROLOGY, 19(1), 20191024
- Potential of Helicobacter pylori-uninfected signet ring cell carcinoma to invade the submucosal layer, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 34(11), 1955-1962, 201911
- Clinical Utility of Emergency Capsule Endoscopy for Diagnosing the Source and Nature of Ongoing Overt Obscure Gastrointestinal Bleeding, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2019, 20191201
- Investigation of Fluorodeoxyglucose Positron Emission Tomography for the Diagnosis of Solid Pseudopapillary Neoplasm of the Pancreas A Study Associated With a National Survey of Solid Pseudopapillary Neoplasms, PANCREAS, 48(10), 1312-1320, 2019
- Regression of Idiopathic Thrombocytopenic Purpura in a Patient With Eradication of Hepatitis C Virus by Direct-Acting Antivirals, HEPATOLOGY, 71(1), 389-391, 202001
- Clinical Usefulness of Dual Red Imaging in Gastric Endoscopic Submucosal Dissection: A Pilot Study, CLINICAL ENDOSCOPY, 53(1), 54-59, 202001
- A Cost-Effectiveness Analysis of Glecaprevir/Pibrentasvir Versus Existing Direct-Acting Antivirals to Treat Chronic Hepatitis C in Japan, ADVANCES IN THERAPY, 37(1), 457-476, 202001
- Management of refractory ascites attenuates muscle mass reduction and improves survival in patients with decompensated cirrhosis, JOURNAL OF GASTROENTEROLOGY, 55(2), 217-226, 202002
- Preoperative PET-CT is useful for predicting recurrent extrahepatic metastasis of hepatocellular carcinoma after resection, EUROPEAN JOURNAL OF RADIOLOGY, 124, 202003
- A case of primary malignant melanoma of the esophagus with a widely expanded surface area, CLINICAL JOURNAL OF GASTROENTEROLOGY, 12(5), 424-428, 201910
- Diagnostic Criteria of Flow-Mediated Vasodilation for Normal Endothelial Function and Nitroglycerin-Induced Vasodilation for Normal Vascular Smooth Muscle Function of the Brachial Artery, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 9(2), 20200121
- Clinical outcomes of endoscopic resection for superficial non-ampullary duodenal tumors, ENDOSCOPY INTERNATIONAL OPEN, 8(3), E354-E359, 202003
- Clinical usefulness of the S-O clip during colorectal endoscopic submucosal dissection in difficult-to-access submucosal layer, ENDOSCOPY INTERNATIONAL OPEN, 8(3), E437-E444, 202003
- Successful retreatment with 12 weeks of glecaprevir and pibrentasvir for a genotype 2a HCV-infected hemodialysis patient who failed to respond to 8 weeks of prior glecaprevir and pibrentasvir therapy, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(2), 267-270, 202004
- The Evaluation of Esophageal Motility Using Infusion Manometry with a Trans-nasal Endoscope: A Preliminary Study, INTERNAL MEDICINE, 59(7), 887-890, 2020
- Three Children Treated with Direct-acting Antivirals for Chronic Hepatitis C Virus Genotype 1b Infection, INTERNAL MEDICINE, 59(7), 941-944, 2020
- Serum amyloid A is a better predictive biomarker of mucosal healing than C-reactive protein in ulcerative colitis in clinical remission, BMC GASTROENTEROLOGY, 20(1), 20200403
- Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations, EBIOMEDICINE, 53, 202003
- Genomic Characterization of Non-Invasive Differentiated-Type Gastric Cancer in the Japanese Population, CANCERS, 12(2), 202002
- Sinusoidal obstruction syndrome post-treatment with trastuzumab emtansine (T-DM1) in advanced breast cancer, INTERNATIONAL CANCER CONFERENCE JOURNAL, 9(1), 18-23, 202001
- Comparative study on the replication of HCV1b genome between wild-type and cell culture-adaptive mutant in regard to sensitivities against anti-HCV drugs, MICROBIOLOGY AND IMMUNOLOGY, 64(4), 296-303, 202004
- Skeletal Muscle Loss during Tyrosine Kinase Inhibitor Treatment for Advanced Hepatocellular Carcinoma Patients, LIVER CANCER, 9(2), 148-155, 202004
- Predicting atrial fibrillation using a combination of genetic risk score and clinical risk factors, HEART RHYTHM, 17(5), 699-705, 202005
- Pan-cancer analysis of whole genomes, NATURE, 578(7793), 82-+, 20200206
- Population Pharmacokinetics of Glecaprevir/Pibrentasvir in HCV-infected Japanese Subjects in Phase 3 CERTAIN-1 and CERTAIN-2 Trials, JOURNAL OF CLINICAL PHARMACOLOGY, 60(3), 331-339, 202003
- Isolated cardiac metastases of hepatocellular carcinoma after resection: a case report, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(3), 421-427, 202006
- JNJ-4178 (adafosbuvir, odalasvir, and simeprevir) in Japanese patients with chronic hepatitis C virus genotype 1 or 2 infection with or without compensated cirrhosis: the Phase IIa OMEGA-3 study, JOURNAL OF GASTROENTEROLOGY, 55(6), 640-652, 202006
- Serum miR-379 expression is related to the development and progression of hypercholesterolemia in non-alcoholic fatty liver disease, PLOS ONE, 15(2), 20200227
- Diagnostic Yield of Colon Capsule Endoscopy in Detection of Superficial Colorectal Lesions, DIGESTION, 101(3), 262-269, 202005
- Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib, THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 12, 202005
- Discordant pathological diagnosis of non-alcoholic fatty liver disease: A prospective multicenter study, JGH OPEN, 4(3), 497-502, 202006
- Impact of the introduction of direct-acting anti-viral drugs on hepatocarcinogenesis: a prospective serial follow-up MRI study, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 52(2), 359-370, 202007
- Efficacy of a self-management program in patients with chronic viral hepatitis in China, BMC NURSING, 18(1), 20190918
- Renal metastasis from primary hepatocellular carcinoma: a case report, INTERNATIONAL CANCER CONFERENCE JOURNAL, 9(3), 141-145, 202007
- Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases, NATURE GENETICS, 52(7), 669-+, 202007
- Diminished hepatic IFN response following HCV clearance triggers HBV reactivation in coinfection, JOURNAL OF CLINICAL INVESTIGATION, 130(6), 3205-3220, 20200601
- Incidence of microsatellite instability-high hepatocellular carcinoma among Japanese patients and response to pembrolizumab, HEPATOLOGY RESEARCH, 50(7), 885-888, 202007
- Increased arterial stiffness and cardiovascular risk prediction in controlled hypertensive patients with coronary artery disease: post hoc analysis of FMD-J (Flow-mediated Dilation Japan) Study A, HYPERTENSION RESEARCH, 43(8), 781-790, 202008
- Hematocrit, hemoglobin and red blood cells are associated with vascular function and vascular structure in men, SCIENTIFIC REPORTS, 10(1), 20200710
- Risk factors for histological progression of non-alcoholic steatohepatitis analyzed from repeated biopsy cases, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 35(8), 1412-1419, 202008
- Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma, CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 11, 202005
- Vascular function is further impaired in subjects aged 80 years or older, HYPERTENSION RESEARCH, 43(9), 914-921, 202009
- Clinical and genomic characteristics of mucosal signet-ring cell carcinoma in Helicobacter pylori-uninfected stomach, BMC GASTROENTEROLOGY, 20(1), 20200729
- Modifying Effect of Chronic Atrophic Gastritis on Radiation Risk for Noncardia Gastric Cancer According to Histological Type, RADIATION RESEARCH, 194(2), 180-187, 202008
- Metabolomic/lipidomic-based analysis of plasma to diagnose hepatocellular ballooning in patients with non-alcoholic fatty liver disease: A multicenter study, HEPATOLOGY RESEARCH, 50(8), 955-965, 202008
- PD1 gene polymorphism is associated with a poor prognosis in hepatocellular carcinoma following liver resection, cohort study, INTERNATIONAL JOURNAL OF SURGERY, 80, 84-90, 202008
- Relationship between high-density lipoprotein cholesterol levels and endothelial function in women: a cross-sectional study, BMJ OPEN, 10(7), 2020
- Treatment outcomes after splenectomy with gastric devascularization or balloon-occluded retrograde transvenous obliteration for gastric varices: a propensity score-weighted analysis from a single institution, JOURNAL OF GASTROENTEROLOGY, 55(9), 877-887, 202009
- Japan Society of Hepatology Guidelines for the Management of Hepatitis B Virus Infection: 2019 update, HEPATOLOGY RESEARCH, 50(8), 892-923, 202008
- Real-world learning curve analysis of colorectal endoscopic submucosal dissection: a large multicenter study, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 34(8), 3344-3351, 202008
- A case of advanced HCC treated with lenvatinib after hepatic arterial infusion chemotherapy combined with radiation therapy treatment for portal vein tumor thrombosis in the main trunk, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(5), 839-843, 202010
- Culture density contributes to hepatic functions of fresh human hepatocytes isolated from chimeric mice with humanized livers: Novel, long-term, functional two-dimensionalin vitrotool for developing new drugs, PLOS ONE, 15(9), 20200911
- Hepatic Arterial Infusion Chemotherapy versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma, LIVER CANCER, 9(5), 583-595, 202009
- Complete response to pembrolizumab in advanced hepatocellular carcinoma with microsatellite instability, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(5), 867-872, 202010
- Detection of acute toxicity of aflatoxin B1 to human hepatocytesin vitroandin vivousing chimeric mice with humanized livers, PLOS ONE, 15(9), 20200923
- Trends in Hepatic Functional Reserve of Patients with Hepatocellular Carcinoma Treated with Tyrosine Kinase Inhibitors, ONCOLOGY, 98(10), 727-733, 202010
- Liver fibrosis assessments using FibroScan, virtual-touch tissue quantification, the FIB-4 index, and mac-2 binding protein glycosylation isomer levels compared with pathological findings of liver resection specimens in patients with hepatitis C infection, BMC GASTROENTEROLOGY, 20(1), 20200925
- Modeling-Based Response-Guided Glecaprevir-Pibrentasvir Therapy for Chronic Hepatitis C to Identify Patients for Ultrashort Treatment Duration, JOURNAL OF INFECTIOUS DISEASES, 222(7), 1165-1169, 20201001
- Pre-impaired fasting glucose state is a risk factor for endothelial dysfunction: Flow-mediated Dilation Japan (FMD-J) study, BMJ OPEN DIABETES RESEARCH & CARE, 8(1), 2020
- Analysis of Post-Progression Survival in Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib, ONCOLOGY, 98(11), 787-797, 202011
- Impact of viral eradication by direct-acting antivirals on the risk of hepatocellular carcinoma development, prognosis, and portal hypertension in hepatitis C virus-related compensated cirrhosis patients, HEPATOLOGY RESEARCH, 50(11), 1222-1233, 202011
- Decrease in fasting insulin secretory function correlates with significant liver fibrosis in Japanese non-alcoholic fatty liver disease patients, JGH OPEN, 4(5), 929-936, 202010
- Fluoxazolevir inhibits hepatitis C virus infection in humanized chimeric mice by blocking viral membrane fusion, NATURE MICROBIOLOGY, 5(12), 1532-+, 202012
- Pilot study of tenofovir disoproxil fumarate and pegylated interferon-alpha 2a add-on therapy in Japanese patients with chronic hepatitis B, JOURNAL OF GASTROENTEROLOGY, 55(10), 977-989, 202010
- Real-word efficacy of sofosbuvir, velpatasvir plus ribavirin therapy for chronic hepatitis patients who failed to prior DAA therapy with NS5A-P32 deletion mutated HCV infection, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(6), 1233-1238, 202012
- A Comparison of Adrenalectomy and Eplerenone on Vascular Function in Patients with Aldosterone-producing Adenoma, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 105(11), 202011
- Real-world efficacy of sofosbuvir plus velpatasvir therapy for patients with hepatitis C virus-related decompensated cirrhosis, HEPATOLOGY RESEARCH, 50(11), 1234-1243, 202011
- PNPLA3andHLA-DQB1polymorphisms are associated with hepatocellular carcinoma after hepatitis C virus eradication, JOURNAL OF GASTROENTEROLOGY, 55(12), 1162-1170, 202012
- Stromal reaction inhibitor and immune-checkpoint inhibitor combination therapy attenuates excluded-type colorectal cancer in a mouse model, CANCER LETTERS, 498, 111-120, 20210201
- Low Levels of Low-Density Lipoprotein Cholesterol and Endothelial Function in Subjects without Lipid-Lowering Therapy, JOURNAL OF CLINICAL MEDICINE, 9(12), 202012
- Clinical significance of endoscopic ultrasonography in diagnosing invasion depth of early gastric cancer prior to endoscopic submucosal dissection, GASTRIC CANCER, 24(1), 145-155, 202101
- Usefulness of linked color imaging in the early detection of superficial esophageal squamous cell carcinomas, ESOPHAGUS, 18(1), 118-124, 202101
- Eradication of hepatitis C virus with direct-acting antivirals improves glycemic control in diabetes: A multicenter study., JGH open : an open access journal of gastroenterology and hepatology, 5(2), 118-234, 20210201
- A case with life-threatening secondary sclerosing cholangitis caused by nivolumab., Clinical journal of gastroenterology, 14(1), 283-287, 20210201
- Abatacept treatment for patients with severe acute hepatitis caused by hepatitis B virus infection-Pilot study., Journal of viral hepatitis, 28(2), 400-409, 20210201
- Association of Body Mass Index with Endothelial Function in Asian Men., International journal of cardiology, 324, 186-192, 20210201
- Role of Endoscopic Ultrasonography and Endoscopic Retrograde Cholangiopancreatography in the Diagnosis of Pancreatic Cancer., Diagnostics (Basel, Switzerland), 11(2), 20210204
- Type IV Collagen 7S Is the Most Accurate Test For Identifying Advanced Fibrosis in NAFLD With Type 2 Diabetes., Hepatology communications, 5(4), 559-572, 20210401
- Clinical usefulness of combination therapy with polidocanol injection and argon plasma coagulation for gastric antral vascular ectasia., JGH open : an open access journal of gastroenterology and hepatology, 5(4), 465-469, 20210401
Publications such as books
- 2006, Molecular pathologic application as a predictor of lymph node metastasis in submucosal colorectal carcinoma:implication of immunohistochemical alterations at the deepest invasive margin , 2006, 04, Scholarly Book, Joint work, 171
- 2005, Role of invariant natural killer T cells in the regulation of the inflammatory response in experimental colitis in mice , 2005, 12, Scholarly Book, Joint work, 35
- 1998, Methods in molecular medicine-hepatitis C protocols. Genotyping hepatitis C virus by type-specific primers for PCR based on NS5 region. , Humana Press, 1998
- 1998, Hepatitis C protocols; Genotyping hepatitis C virus by type-specific primers or PCR based on NS5 region , Humana Press, 1998, Scholarly Book, Single work
- 1994, Viral hepatitis and liver disease. High virus titer, slow virus decrease, genotype(]G0002[), and sequence variability of E2/NS1 HVR predict poor response to interferon therapy in chronic hepatitis C. , Springer Verlag, 1994
- 1994, High virus titer, slow virus decrease, genotypeII, and sequence variability of E2/NS1 HVR predict poor response to interferon therapy in chronic hepatitis C Viral hepatitis and liver disease , Springer Verlag, 1994
- 2017, Hepatotos C Virus Treatment, Highly Effective Therapy with Direct Acting Antivirals and Associated Viral Resistance, Springer, 2017, Scholarly Book, Compilation
- 2017/09/05, Hepatitis B Virus and Liver Desease, Unmet Needs in Basic Research: In Vitro and In Vivo Models, Springer Nature Singapore Pre Ltd., 2018, 2018, Scholarly Book, Cocompilation, Kazuaki Chayama, Nelson Hayes.
- 2017/09/30, Management for DAA resistant-associated variants, Management for DAA resistant-associated variants, 2017, 9月
- 2017/12, The Liver Cancer Journal, Meeting Report
- 2018, Clinics in Gastroenterology, 2018, Book(general), Supervisor
Invited Lecture, Oral Presentation, Poster Presentation
- chronic hepatitis virus infection and interferon, 2017/10/30, Without Invitation, Japanese
- Baselin RAS Test: Clinical practice, The Liver Week 2017, 2017/06/23, With Invitation, Japanese, Korea
- Efficacy and safety of Glecaprevir/Pibrentasvir in Japanese Patients with Chronic GT1 Hepatitis C Virus Infection with and without Cirrhosis, 2017/06/09, Without Invitation, English, Hiroshima city
- Recent Progress in Treatment for Chronic Hepatitis C for Genotype 1, Asian Pacific Association for the Study of the Liver Single Topic Conference(APASL STC), 2017/04/11, Without Invitation, English, Nagasaki city
- Targeting Host and Viral Interactions: Insights from Mice Model, Asian Pacific Association for the Study of the Liver 2017(APASL 2017), 2017/02/17, With Invitation, English, Shanghai
- Recent Progress in Treatment for Chronic Hepatitis C, APDW2016, 2016/11/05, Without Invitation, English
- Practical Therapy of Chronic Hepatitis C, 2016/10/12, Without Invitation, English, Kyoto
- Integrated safety and Tolerability of DCV+ASV in Patients with Chronic HCV Genotype 1b Infection, 2016 APASL Single Topic Conference on Hepatitis C, 2016/06/12, Without Invitation, English, Kaohsiung (Taiwan)
- Best Strategy for Curing HCV Genotype 1 and 4: East vs. West, 2016 APASL Single Topic Conference on Hepatitis C, 2016/06/11, Without Invitation, Japanese, Kaohsiung city (Taiwan)
- A mouse model of human CTL mediated severe acute hepatitis B, 2016/05/20, Without Invitation, English, Makuhari
- HCV Treatiment Update-a New Era of All-oral HCV Treatment, The 46th Annual Meeting of GEST and The 25th Annual Meeting of DEST, 2016/03/26, With Invitation, English, Taipei
- GIFT-1:Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir in Elderly Japanese Patients, Asian Pacific Association for the Study of the Liver 2016(APASL 2016) (アジア太平洋肝臓病学会議), 2016/02/22, Without Invitation, Japanese, Tokyo
- Chimeric Animal Model, Asian Pacific Association for the Study of the Liver 2016(APASL 2016) (アジア太平洋肝臓病学会議), 2016/02/22, Without Invitation, Japanese, Tokyo
- DAA/PR therapy in Asian HCV patients, 2015/12/04, With Invitation, Japanese
- Circulating Tumor DNA Analysis for HCC., 2015/10/26, With Invitation, English
- Circulating Tumor DNA Analysis for HCC., 2015/10/26, Without Invitation, Japanese
- All Oral Direct Acting Antiviral Therapy for Chronic Hepatitis C, 2015/10/17, With Invitation, English
- Ombitasvir/Paritaprevir/Ritonavir for treatment of HCV genotype 1b in Japanese patients with or without Cirrhosis: results from GIFT-1, 2015/05/22, Without Invitation, English
- Hepatitis B mouse model involving CTL, 2015/04/23, Without Invitation, English, other
- All-oral Dual Combination of Daclatasvir plus Asunaprevir Compared with Telaprevir plus Peginterferon Alfa/Ribavirin in Treatment-maive Japanese Patients ChronicallyInfected with HCV Genotype 1b:Results from a Phase 3 Study, chayama kazuaki, 2014/11/11, Without Invitation
- Optimizing triple therapy, and IFN/RBV free regimens, chayama kazuaki, 2014/03/12, Without Invitation, Japanese
- Recent Progress in Treatment for Chronic Hepatitis C for Genotype 1, Asian Pacific Association for the Study of the Liver Single Topic Conference(APASL STC), Without Invitation, English, Nagasaki city
- Recent Progress in Treatment for Chronic Hepatitis C for Genotype 1, Asian Pacific Association for the Study of the Liver Single Topic Conference(APASL STC), Without Invitation, English, Nagasaki
Awards
- 1997/11, Award of The Japan Gastroenterological Endoscopy Society, The Japan Gastroenterological Endoscopy Society, The Superiority of Laparoscopic Examination in Predicting Hepatocellular Carcinoma after Interferon Therapy for Chronic
- 2008/01, GlaxoSmithKline Award
Patented
- Patent, JP5152745, 2012/12/14
- Patent
- Patent, JP2869759, 1999/01/08
- Patent, JP5656159, 2014/12/05
- Patent, JP5696317, 2015/02/20
- Patent, JP5888668, 2016/02/26
- Patent, JP5924644, 2016/04/28
- Patent
- Patent
- Patent
- Patent
- Patent
- Patent
- Patent
- Patent, 2014/12/05
- Patent
- Patent
- Patent
- Patent
Works, etc.
- 広島大学ラグビー部顧問,第32回中国四国医科学生ラグビーフットボール大会 広島大学優勝
External Funds
Acceptance Results of Competitive Funds
- 2021/04/01, 2023/03/31
- Research Program on Hepatitis, 2015/04/01, 2016/03/31
- Research Program on Hepatitis, 2015/04/01, 2016/03/31
- Health and Labour Sciences Research Grants, 2011, 2013
- Health and Labour Sciences Research Grants, 2012, 2016
- 2001
- 2003
- 2004
- 2004
- 2004
- 2006
- 2005
- 2007
- 2007
- 2008
- 2009
- 2009
- 2010
- 2010
- KAKENHI, 2014, 2014
- KAKENHI, Identification of SNPs on mature micro RNA to analyze origin of miRNA, 2013, 2013
- KAKENHI, Analysis of unknown pathogen using human hepatocyte chimeric mouseand massive parallel sequencing, 2012, 2012
- KAKENHI, Generation of a mouse model that shows specific features of human diseases., 2010, 2011
- KAKENHI, A comprehensive transcriptome analysis of humanized mouse liver using ultra high density cDNA micro array, 2009, 2011
- KAKENHI, 2007, 2007
- KAKENHI, Production of interferon stimulated gene library and screening of new therapeutic drug for hepatitis viruses, 2006, 2007
- KAKENHI, 2003, 2005
- KAKENHI, Specification of the factor in a liver cell required for multiplication of hepatitis C virus, 2001, 2003
- KAKENHI, Analysis of lamivudine resistance acquisition by hepatitis B virus., 2001, 2003
- KAKENHI, Detection of drug resistant mutant hepatitis B virus strain and its clinical application., 1998, 2000
- KAKENHI, Interferon resistance of hepatitis C virus, 1994, 1995
- Health and Labour Sciences Research Grants, 2014/04/01, 2015/03/31
- KAKENHI, 2015, 2016
- Research Program on Hepatitis , 2016/04/01, 2017/03/31
- Research Program on Hepatitis , 2016/04/01, 2017/03/31
- KAKENHI(Grant-in-Aid for Challenging Research (Pioneering)), 2017, 2019
- Research Program on Hepatitis , 2017/04/01, 2018/03/31
- Research Program on Hepatitis , 2017/04/01, 2018/03/31
- 2004/04/01
- 2017
Social Activities
Organizing Academic Conferences, etc.
- 2000/11
- 2001/10
- 2001/05
- 2001/10
- 2001/11
- 2001/02
- 2001/11
- 2001/02
- 2001/07
- 2001/07
- 2001/04
- 2001/05
- 2001/09
- 2001/12
- 2001/01
- 2009/09
- 2011/10
- 2012/02
- The 2nd Japan-Italy Liver Workshop, 2014/11, 2014/11
- The 11th JSH Single Topic Conference, 2014/11
- 2014/07
- 2016/11
- 2015/11, 2015/11
- 2017/06, 2017/06
- 2016/06, 2016/06
- 2017/07, 2017/07
Other Social Contributions
- Pancreatic Cancer Expert Meeting, 2017/05/26, 2017/05/26, Others
- Academic Workshop by Hiroshima University and Cairo University, Human hepatocyte chimeric mouse model for hepatitis virus studies, 2017/02/21, 2017/02/21