SHINJI OHTA

Last Updated :2023/11/01

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Professor
E-mail
ohtahiroshima-u.ac.jp
Self-introduction
I am investigating the structure and function of new bioactive natural compounds derived from marine organisms, plants, and insects, and aiming to develop new drug lead compounds that are candidates for anticancer agents, therapeutic agents for intractable neurodegenerative diseases, and diabetes-improving agents, etc.

Basic Information

Academic Degrees

  • Doctor of Science, Hiroshima University
  • Master of Science, Hiroshima University

Educational Activity

  • [Bachelor Degree Program] School of Applied Biological Science : Department of Applied Biological Science : Molecular Agro-Life Science Program
  • [Master's Program] Graduate School of Advanced Science and Engineering : Division of Advanced Science and Engineering : Transdisciplinary Science and Engineering Program
  • [Master's Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Food and AgriLife Science
  • [Doctoral Program] Graduate School of Advanced Science and Engineering : Division of Advanced Science and Engineering : Transdisciplinary Science and Engineering Program
  • [Doctoral Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Food and AgriLife Science

Research Fields

  • Complex systems;Biomolecular science;Biomolecular chemistry

Research Keywords

  • Structure-Bioactivity Relationship
  • Natural Products
  • Biological Activity

Educational Activity

Course in Charge

  1. 2023, Liberal Arts Education Program1, 3Term, Organic Chemistry
  2. 2023, Liberal Arts Education Program1, 1Term, Basic Laboratory Work in Chemistry
  3. 2023, Undergraduate Education, Second Semester, Graduation Thesis I
  4. 2023, Undergraduate Education, First Semester, Graduation Thesis II
  5. 2023, Undergraduate Education, Second Semester, Graduation Thesis III
  6. 2023, Undergraduate Education, Intensive, Laboratory Work in Molecular Agro-life Science I
  7. 2023, Undergraduate Education, 4Term, Chemistry of natural organic compounds
  8. 2023, Undergraduate Education, 2Term, Biofunctional Chemistry
  9. 2023, Undergraduate Education, 4Term, Bio-Analytical Science
  10. 2023, Undergraduate Education, 3Term, Reading of Foreign Literature in Molecular Agro-Life Science
  11. 2023, Graduate Education (Master's Program) , 1Term, Exercises in Food andAgriLife Science A
  12. 2023, Graduate Education (Master's Program) , 2Term, Exercises in Food andAgriLife Science A
  13. 2023, Graduate Education (Master's Program) , 3Term, Exercises in Food andAgriLife Science B
  14. 2023, Graduate Education (Master's Program) , 4Term, Exercises in Food andAgriLife Science B
  15. 2023, Graduate Education (Master's Program) , 2Term, Bioactive Natural Products Chemistry I
  16. 2023, Graduate Education (Master's Program) , 4Term, Bioactive Natural Products Chemistry II

Research Activities

Academic Papers

  1. ★, Isolation of Fluorescent Benzoxazines with Neuroprotective Activity from the Olive Weevil Pimelocerus perforatus, Journal of Natural Products, 85(12), 2740-2745, 20221223
    Link to Paper Search Results by DOI
  2. Triterpenoid Saponins from the Fruits of Symplocos lucida as beta-Glucuronidase Inhibitors, CHEMISTRY & BIODIVERSITY, 19(11), 202211
    Link to Paper Search Results by DOI
  3. Acylated secoiridoid glucosides isolated from the fruit extract of Symplocos lucida inhibit beta-glucuronidase, PHYTOCHEMISTRY LETTERS, 51, 127-131, 202210
    Link to Paper Search Results by DOI
  4. Antibacterial, Anti-Inflammatory, and Antidiabetic Studies of the Amines Isolated from the Philippine Marine Sponge Desmacella sp., Current Bioactive Compounds, 19(1), e090522204450-e090522204450, 20220624
    Link to Paper Search Results by DOI
  5. Polyhydroxy Acids as Fabaceous Plant Components Induce Oviposition of the Common Grass Yellow Butterfly, Eurema Mandarina, JOURNAL OF CHEMICAL ECOLOGY, 49(1-2), 67-76, 202302
    Link to Paper Search Results by DOI
  6. Characterization of volatile compounds in males of the skipper butterfly Daimio tethys (Lepidoptera: Hesperiidae), APPLIED ENTOMOLOGY AND ZOOLOGY, 58(2), 171-179, 202305
    Link to Paper Search Results by DOI
  7. Sex pheromones from male forewings of the Common Grass Yellow Eurema mandarina, JOURNAL OF CHEMICAL ECOLOGY, 48(5-6), 518-530, 202206
    Link to Paper Search Results by DOI
  8. Electrospray ionization mass spectrometry and nuclear magnetic resonance spectroscopy data for anacardic acid derivatives, DATA IN BRIEF, 41(1), 107889-107889, 202204
    Link to Paper Search Results by DOI
  9. Chemical Identity of Cuticular Lipid Components in the Mimetic Swallowtail Butterfly Papilio polytes, CHEMISTRY & BIODIVERSITY, 19(3), e202100879-e202100879, 202203
    Link to Paper Search Results by DOI
  10. Janohigenins: Long-chain anacardic acid derivatives with neuroprotective activity from Ophiopogon japonicus seeds, PHYTOCHEMISTRY, 191, 202111
    Link to Paper Search Results by DOI
  11. Oxygenated Cembrene Diterpenes from Sarcophyton convolutum: Cytotoxic Sarcoconvolutum A-E, MARINE DRUGS, 19(9), 202109
    Link to Paper Search Results by DOI
  12. Paralemnolins X and Y, New Antimicrobial Sesquiterpenoids from the Soft Coral Paralemnalia thyrsoide, Antibiotics, 10(10), 1158, 20210924
    Link to Paper Search Results by DOI
  13. Variation in cuticular lipid profiles of black butterflies of the genus Papilio in Japan, BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 96, 202106
    Link to Paper Search Results by DOI
  14. ★, Asaroidoxazines from the Roots of Asarum asaroides Induce Apoptosis in Human Neuroblastoma Cells, JOURNAL OF NATURAL PRODUCTS, 83(10), 3050-3057, 20201023
    Link to Paper Search Results by DOI
  15. Rare sulfated purine alkaloid glycosides from Bruchidius dorsalis pupal case, Phytochemistry Letters, 35(1), 10-14, 20200201
    Link to Paper Search Results by DOI
  16. Carotane sesquiterpenes fromFerula vesceritensis:in silicoanalysis as SARS-CoV-2 binding inhibitors, RSC ADVANCES, 10(57), 34541-34548, 20200920
    Link to Paper Search Results by DOI
  17. Nuclear magnetic resonance spectroscopy and mass spectrometry data for sulfated isoguanine glycosides, Data in Brief, 28(1), 105032-105032, 20200201
    Link to Paper Search Results by DOI
  18. The male swallowtail butterfly, Papilio polytes, uses cuticular hydrocarbons for mate discrimination, ANIMAL BEHAVIOUR, 170, 133-145, 20201201
    Link to Paper Search Results by DOI
  19. Absence of cuticular alkenes allows lycaenid larvae to avoid predation by Formica japonica ants, Entomological Science, 22(2), 126-136, 20190411
  20. The Role of N,N,N-Trimethylglycine in Oviposition of Eurema mandarina on Albizia julibrissin, JOURNAL OF CHEMICAL ECOLOGY, 45(4), 371-377, 201904
    Link to Paper Search Results by DOI
  21. Norbisabolane and bisabolane sesquiterpenoids from the seeds of Angelica keiskei and absolute configuration of ashitabaol A and bisabolangelone, Phytochemistry Letters, 33(1), 94-101, 20191001
  22. A cyanogenic glucoside of Trifolium repens deters oviposition by the common grass yellow Eurema mandarina, PHYSIOLOGICAL ENTOMOLOGY, 44(3-4), 222-229, 201912
    Link to Paper Search Results by DOI
  23. NMR and ESIMS data for bisabolane-type sesquiterpenoids, Data in Brief, 27(1), 104780-104780, 20191201
    Link to Paper Search Results by DOI
  24. Sarcoehrenbergilid D-F: cytotoxic cembrene diterpenoids from the soft coral Sarcophyton ehrenbergi, RSC Advances, 9(47), 27183-27189, 20190829
    Link to Paper Search Results by DOI
  25. 4′,6-Dimethoxyisoflavone-7-O-β-D-glucopyranoside (wistin) is a peroxisome proliferator-activated receptor α (PPARα) agonist in mouse hepatocytes, Molecular and Cellular Biochemistry, 446(1-2), 35-41, 20180901
  26. HPLC profiles and spectroscopic data of cassane-type furanoditerpenoids, Data in Brief, 21, 1076-1088, 20181201
  27. ★, Hydroxylated furanoditerpenoids from pupal cases produced by the bruchid beetle Sulcobruchus sauteri inside the seeds of Caesalpinia decapetala, Phytochemistry, 156, 151-158, 20181201
  28. Oxygenated sesquiterpenoids characteristic of a male lycaenid butterfly Lycaeides argyrognomon praterinsularis, Biochemical Systematics and Ecology, 81, 109-111, 20181201
  29. Cytotoxicity of abietane diterpenoids from Salvia multicaulis towards multidrug-resistant cancer cells, Fitoterapia, 130, 54-60, 20181001
  30. ★, Sulfated purine alkaloid glycosides from the pupal case built by the bruchid beetle Bruchidius dorsalis inside the seed of Gleditsia japonica, Chem. Biodiversity, 15(8), e1800154-e1800154, 20180813
  31. New prenylated ortho-dihydroxycoumarins from the fruits of Ficus nipponica, Chemistry and Biodiversity, 14(9), e1700196-e1700196, 20170913
  32. Ficunotins A-F: Rare diarylbutanoids from the leaves of Ficus nota, Phytochemistry, 141(1), 98-104, 20170901
  33. Cembrene Diterpenoids with Ether Linkages from Sarcophyton ehrenbergi: An Anti-Proliferation and Molecular-Docking Assessment, MARINE DRUGS, 15(6), 192-192, 20170621
    Link to Paper Search Results by DOI
  34. Prenylated purine alkaloids from seeds of Gleditsia japonica, Phytochemistry, 143(1), 145-150, 20171101
  35. LS-187R1: Volatile compounds from a Parnassiinae butterfly, Luehdorfia japonica (Lepidoptera: Papilionidae), Lepidoptera Science, 68(2), 61-64, 20170801
  36. Two new C11-terpenes with an octahydrobenzofuran skeleton isolated from the leaves of Ficus nota, PHYTOCHEMISTRY LETTERS, 19(1), 237-240, 20170301
    Link to Paper Search Results by DOI
  37. Volatile terpenoids from male wings lacking scent scales in Anthocharis scolymus (Lepidoptera: Pieridae), APPLIED ENTOMOLOGY AND ZOOLOGY, 51(3), 385-392, 201608
    Link to Paper Search Results by DOI
  38. Casbane Diterpenes from Red Sea Coral Sinularia polydactyla, Molecules, 21(3), 308-315, 20160303
    Link to Paper Search Results by DOI
  39. Structure Revision of Caesalpinista A and Caesalpinista B and Isolation of a New Furanoditerpenoid from the Cotyledons of Caesalpinia decapetala var. japonica, Helvetica Chimica Acta, 99(2), 133-137, 20160201
    Link to Paper Search Results by DOI
  40. D-Pinitol in Fabaceae: an Oviposition Stimulant for the Common Grass Yellow Butterfly, Eurema mandarina, JOURNAL OF CHEMICAL ECOLOGY, 42(11), 1122-1129, 20161006
    Link to Paper Search Results by DOI
  41. 4,6-dimethoxyisoflavone-7-O--D-glucopyranoside (wistin) is a peroxisome proliferator-activated receptor (PPAR) agonist that stimulates adipocyte differentiation, ANIMAL SCIENCE JOURNAL, 87(11), 1347-1351, 20161023
    Link to Paper Search Results by DOI
  42. ★, Cassane diterpenoids from the roots of Caesalpinia decapetala var. japonica and structure revision of caesaljapin, PHYTOCHEMISTRY, 121(1), 50-57, 20160101
    Link to Paper Search Results by DOI
  43. Caesaljaponins A and B: New Cassane-type Furanoditerpenoids from the Seeds of Caesalpinia decapetala var. japonica, Helvetica Chimica Acta, 98(3), 336-342, 20150313
    Link to Paper Search Results by DOI
  44. New cytotoxic halogenated sesquiterpenes from the Egyptian sea hare, Aplysia oculifera, TETRAHEDRON LETTERS, 55(10), 1711-1714, 20140305
    Link to Paper Search Results by DOI
  45. New Terpenes from the Egyptian Soft Coral Sarcophyton ehrenbergi, MARINE DRUGS, 12(4), 1977-1986, 201404
    Link to Paper Search Results by DOI
  46. New Guaianolide-Type Sesquiterpene Lactones from Inula verbascifolia, Zeitschrift fuer Naturforschung, 68(5, 6), 175-180, 201305
  47. Bromotheoynic acid, a brominated acetylenic acid from the marine sponge Theonella swinhoei, Natural Product Research, 27(2), 117-122, 20130101
  48. Petroacetylene, a new polyacetylene from the marine sponge Petrosia solida that inhibits blastulation of starfish embryos, NATURAL PRODUCT RESEARCH, 27(20), 1842-1847, 20131001
    Link to Paper Search Results by DOI
  49. ★, Dorsamin-A's, Glycerolipids Carrying a Dehydrophenylalanine Ester Moiety from the Seed-Eating Larvae of the Bruchid Beetle Bruchidius dorsalis, JOURNAL OF NATURAL PRODUCTS, 76(4), 554-558, 2013
    Link to Paper Search Results by DOI
  50. Investigation for antidiabetic agonists from Wisteria floribunda seeds, Trace Nutrients Research, 29, 36-40, 20121201
  51. GABA metabolism pathway genes, UGA1 and GAD1, regulate replicative lifespan in Saccharomyces cerevisiae, BBRC(BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS), 407(1), 185-190, 20110401
  52. Locustoside A-A new purine alkaloid glucoside from seeds of Gleditsia japonica, Phytochemistry Lett, 3(4), 198-200, 20101201
  53. A Novel Human Dynactin-Associated Protein, dynAP, Promotes Activation of Akt, and Ergosterol-Related Compounds Induce dynAP-Dependent Apoptosis of Human Cancer Cells, Molecular Cancer Therapeutics, 9(11), 2934-2942, 20101101
  54. ★, Ashitabaol A, a new antioxidative sesquiterpenoid from seeds of Angelica keiskei, Tetrahedron Letters, 51(26), 3449-3450, 20100801
  55. ★, Saikachinoside A, a novel 3-prenylated isoguanine glucoside from seeds of Gleditsia japonica, Tetrahedron Letters, 51(16), 2099-2101, 20100501
  56. Bioactive jatrophane diterpenes from Euphorbia guyoniana, Phytochemistry, 71(2), 249-253, 20100201
  57. Cytotoxicity of 3-O-(b-D-Glucopyranosyl)etioline, a Steroidal Alkaloid from Solanum diphyllum L., Zeitschrift fur Naturforschung C, 64(9), 644-649, 20090901
  58. Anti-Fertilization Activity of a Spirocyclic Sesquiterpene Isocyanide Isolated from the Marine Sponge Geodia exigua and Related Compounds, Biosci. Biotechnol. Biochem., 72(7), 1764-1771, 20080701
  59. Cyclooxygenase (COX)-1 and -2 Inhibitory Labdane Diterpenes from Crassocephalum mannii, Journal of Natural Products, 71(6), 1070-1073, 20080601
  60. Antioxidant hydroxycinnamic acid derivatives isolated from Brazilian bee pollen, Natural Product Research, 21(8), 726-732, 20070701
  61. Exiguolide, a New Macrolide from the Marine Sponge Geodia exigua, Tetrahedron Lett., 47(12), 1957-1960, 20060301
  62. Sylviside, a Diterpene Glucoside Derivative from Gnaphalium sylvaticum, J. Nat. Prod., 69(3), 394-396, 20060301
  63. Growth and carotenoid production of Thraustochytrium sp CHN-1 cultured under superbright red and blue light-emitting diodes, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 68(7), 1594-1597, 2004
    Link to Paper Search Results by DOI
  64. Two new analogues of the cytotoxic substance BE-52211 from Streptomyces sp, JOURNAL OF NATURAL PRODUCTS, 67(1), 85-87, 2004
    Link to Paper Search Results by DOI
  65. Two New Analogues of the Cytotoxic Substance BE-52211 from Streptomyces sp., J. Nat. Prod., 67(1), 85-87, 20040101
  66. Two new analogues of the cytotoxic substance BE-52211 from Streptomyces sp., J. Nat. Prod, 67(1), 85-87, 20040123
  67. Inhibition of chromosome separation in fertilized starfish eggs by kalihinol F, a topoisomerase I inhibitor obtained from a marine sponge., Biosci. Biotechnol. Biochem., 67(11), 2365-2372, 20031101
  68. Piericidins C5 and C6: new 4-pyridinol compounds produced by Streptomyces sp. and Nocardioides sp., Bioorg. Med. Chem., 11(21), 4569-4575, 20031015
  69. A new alpha,beta,gamma,delta-unsaturated carboxylic acid and three new cyclic peroxides from the marine sponge, Monotria japonica, which selectively lyse starfish oocytes without affecting nuclear morphology., Bioorg. Med. Chem., 11(8), 1715-1721, 2003
  70. A New a,b,g,d-Unsaturated Carboxylic Acid and Three New Cyclic Peroxides from the Marine Sponge, Monotria japonica, Which Selectively Lyse Starfish Oocyte without Affecting Nuclear Morphology, Bioorg. Med. Chem., 20030401
  71. Terpenoid Coumarin of the Genus Ferula, Heterocycles, 60(3), 689-716, 20030301
  72. New Spirocyclic Sesquiterpenes from the Marine Sponge Geodia exigua, Tetrahedron, 59(6), 731-736, 20030201
  73. Malformation of immature starfish oocytes by theonellapeptolide Ie, a Tridecapeptide lactone from a marine sponge Petrosia species, through disturbance of cortical F-actin distribution., Biosci. Biotechnol. Biochem., 67(9), 1908-1915, 20030901
  74. Effects of iron on the degradation of triphenyltin by pyoverdins isolated from Pseudomonas chlororaphis, APPLIED ORGANOMETALLIC CHEMISTRY, 16(5), 277-279, 2002
    Link to Paper Search Results by DOI
  75. Exiguamide, a New Spirocyclic Sesquiterpene from the Marine Sponge Geodia exigua That Inhibits Cell Fate Specification During Sea Urchin Embryogenesis, Bioorg.Med.Chem.Lett., 12(21), 3037-3039, 20021101
  76. A Novel Amphibian Hypothalamic Neuropeptide: Isolation, Localization, and Biological Activity, Endocrinology, 143(2), 411-419, 20020201
  77. Biotransformation of Phenolic Compounds by the Cultured Cells of Catharanthus roseus, J. Mol. Cat. B: Enzym., 16(42861), 275-281, 20020201
  78. Glucosyltransferase in the Cultured Cells of Nicotiana tabacum, Heterocycles, 56(42737), 509-514, 20020101
  79. Exiguamide, a new spirocyclic sesquiterpene from the marine sponge Geodia exigua that inhibits cell fate specification during sea urchin embryogenesis., Exiguamide, a new spirocyclic sesquiterpene from the marine sponge Geodia exigua that inhibits cell fate specification during sea urchin embryogenesis., 12(21), 2002
  80. Micromonospolides A-C, new macrolides from Micromonospora sp., TETRAHEDRON, 57(40), 8463-8467, 20011001
    Link to Paper Search Results by DOI
  81. Ancorinoside A Mg salt from the marine sponge, Ancorina sp., which specifically inhibits blastulation of starfish embryos, TETRAHEDRON, 57(22), 4699-4703, 20010528
    Link to Paper Search Results by DOI
  82. Enantioselective total synthesis and absolute stereostructure of hippospongic acid A, TETRAHEDRON, 57(7), 1235-1246, 20010211
    Link to Paper Search Results by DOI
  83. Degradation of triphenyltin compounds in sea water by pyoverdins from Pseudomonas chlororaphis, APPLIED ORGANOMETALLIC CHEMISTRY, 15(9), 757-761, 2001
    Link to Paper Search Results by DOI
  84. The Enterins: A Novel Family of Neuropeptides Isolated from the Enteric Nervous System and CNS of Aplysia, J. Neurosci., 21(20), 8247-8261, 20011001
  85. Micromonospolides A-C, New Macrolides from Micromonospora sp., Tetrahedron, 57(40), 8463-8467, 20010901
  86. A Unique Phosphatidylinositol Bearing a Novel Branched-chain Fatty Acid from Rhodococcus equi Binds to Influenza Virus Hemagglutinin and Inhibits the Infection of Cells, J. Biochem., 130(3), 377-384, 20010901
  87. Monoterpene Coumarins from Ferula ferulago, Phytochemistry, 1201-1203, 20010801
  88. Micromonospolide A, a New Macrolide from Micromonospora sp., Tetrahedron Lett., 42(25), 4179-4181, 20010601
  89. An Eudesmanolide and a Carotane from Ferula sinaica, Phytochemistry, 57(4), 513-515, 20010601
  90. Ancorinoside A Mg Salt from the Marine Sponge, Ancorina sp., Which Specifically Inhibits Blastulation of Starfish Embryos, Tetrahedron, 57(22), 4699-4703, 20010501
  91. New Naphthyridinomycin-type Antibiotics, Aclidinomycins A and B, from Streptomyces halstedi, J. Antibiotics, 54(3), 304-307, 20010501
  92. Diastereoselective Formation of Disaccharides from (RS)-1-Phenylethanol by Cultured Cells of Catharanthus roseus, Bull. Chem. Soc. Jpn, 74(3), 539-542, 20010301
  93. Enantioselective Total Synthesis and Absolute Stereostructure of Hippospongic Acid A, Tetrahedron, 57(7), 1235-1246, 20010201
  94. High Production of Prodigiosin by Serratia marcescens Grown on Ethanol, Biotech. Lett., 22(22), 1761-1765, 20001101
  95. Biotransformation of Hydroxycoumarins by the Cultured Cells of Nicotiana tabacum, J. Mol. Cat. B: Enzym., 10(5), 477-481, 20001001
  96. Isolation and Identification of Cell Hypertrophy-inducing Substances in the Gall-forming Aphid Colopha moriokaensis, Insect Biochem. Mol. Biol., 30(10), 947-952, 20001001
  97. Production of a New Hybrid Anthracycline 4-O-methylepelmycin by Heterologous Expression of dnrK in Epelmycin-producing Streptomyces violaceus, J. Antibiot., 53(8), 828-836, 20000801
  98. Glyceroglycolipids Preventing tert-Butylhydroperoxide-Induced Cell Death from Microbacterium sp. and Corynebacterium aquaticum Strains, J. Biosci. Bioeng., 89(2), 170-175, 20000201
  99. A New Type of Glycoglycerolipids from Corynebacterium aquaticum, Biosci. Biotech. Biochem., 64(2), 424-427, 20000201
  100. The Aplysia Mytilus Inhibitory Peptide-Related Peptides: Identification, Cloning, Processing, Distribution, and Action, J. Neurosci., 19(21), 9618-9634, 19991101
  101. Glucosylation of Benzyl Alcohols by the Cultured Suspension Cells of Nicotiana tabacum and Catharanthus roseus, J. Mol. Cat. B: Enzym., 6(1), 67-73, 19990101
  102. Novel Norsesterterpenes, Which Inhibit Gastrulation of the Starfish Embryo, from the Marine Sponge Rhopaloeides sp, Tetrahedron, 54(51), 15607-15612, 19981101
  103. Revised Structure, Synthesis and Absolute Configuration of Hippospongic Acid A, Tetrahedron Lett., 39(42), 7745-7746, 19981001
  104. Study on Food Components: the Structure of N-linked Asialo Carbohydrate from the Edible Bird’s Nest Built by Collocalia fuciphaga, J. Agric. Food Chem., 46(8), 3047-3053, 19980801
  105. Andrimid, an Antimicrobial Substance in the Marine Sponge Hyatella, Produced by an Associated Vibrio Bacterium, Sponge Sciences - Multidisciplinary Perspectives, 391-398, 19980701
  106. A Carotenoid Pigment of the Radioresistant Bacterium Deinococcus radiodurans, Microbios, 95, 79-90, 19980401
  107. Isolation and Characterization of a Novel Bioactive Peptide, Carassius RFamide (C-RFa), from the Brain of the Japanese Crucian Carp, Biochem. Biophys. Res. Commun., 242(2), 436-440, 19980101
  108. A Novel D-Amino-acid-containing Peptide Isolated from Aplysia Heart, Biochem. Biophys. Res. Commun., 240(2), 354-358, 19971101
  109. Biologically Active Clerodane-type Diterpene Glycosides from the Root-stalks of Dicranopteris pedata, Phytochemistry, 46(5), 839-844, 19971101
  110. Arachisprenols: Polyprenols Possessing a Geranyl Residue from Arachis hypogaea, Phytochemistry, 46(4), 715-720, 19971001
  111. Structure of a Covalently Cross-linked Form of Core Histones Present in the Starfish Sperm, Bio chemistry, 36(40), 12071-12079, 19971001
  112. ★, Ancorinoside A: a Novel Tetramic Acid Glycoside from the Marine Sponge, Ancorina sp., Which Specifically Inhibits Blastulation of Starfish Embryos, J. Org. Chem., 62(19), 6452-6453, 19970901
  113. Callyspongins A and B: Novel Polyacetylene Sulfates from the Marine Sponge Callyspongia truncata That Inhibit Fertilization of Starfish Gametes, J. Nat. Prod., 59(12), 1146-1148, 19961201
  114. Structure-Activity Relationships of Cinnamic Acid Derivatives as Germination Inhibitor of the Fern Gleichenia japonica, Nat. Prod. Lett., 9(1), 21-26, 19961101
  115. Hippospongic Acid A: An Unusual Triterpenoic Acid from a Marine Sponge, Hippospongia sp., Which Inhibits Gastrulation of Starfish Embryos, Tetrahedron Lett., 37(43), 7765-7766, 19961001
  116. ★, Rhopaloic Acid A: A Novel Norsesterterpene from a Marine Sponge, Rhopaloeides sp., Which Inhibits Gastrulation of Starfish Embryos, Tetrahedron Lett., 37(13), 2265-2266, 19960501
  117. 24-Epi-pterosterone: A Novel Phytoecdysone from the Roots of Athyrium yokoscense, Phytochemistry, 41(3), 745-747, 19960201
  118. Vibrio Species Isolated from Coastal Ocean Produces Aerobactin, Microbios, 84(341), 231-238, 19951101
  119. Production of an Antibacterial Agent o-Aminophenol, by a Bacterium Isolated from the Marine Sponge, Adocia Sp., Fisheries Science, 60(5), 559-562, 19941001
  120. Selective Inhibition of Exoplasmic Membrane Fusion in Echinoderm Gametes with Jaspisin, a Novel Antihatching Substance Isolated from a Marine Sponge, J. Biol. Chem., 269(37), 23262-23267, 19940901
  121. Jaspisin: A Novel Styryl Sulfate from the Marine Sponge, Jaspis Species, Biosci. Biotech. Biochem., 58(9), 1752-1753, 19940901
  122. A Novel Antimicrobial Substance from a Strain of the Bacterium, Vibrio Sp., Nat. Prod. Lett., 4(4), 309-312, 19940901
  123. Isojaspisin: A Novel Styryl Sulfate from a Marine Sponge, Jaspis Sp., That Inhibits Hatching of Sea Urchin Embryos, Tetrahedron Lett., 35(26), 4579-4580, 19940601
  124. 13C NMR Detection of Delocalized C10-Allylic Cation in the Biosynthesis of Farnesyl Diphosphate, J. Chem. Soc. = Chem. Commun., 1057-1058, 19940501
  125. Anti-bacillus Substance in the Marine Sponge, Hyatella Species, Produced by an Associated Vibrio Species Bacterium, Microbios, 78(314), 7-16, 19940301
  126. Clathrynamides A, B, and C: Novel Amides from a Marine Sponge Clathria Sp. That Inhibit Cell Division of Fertilized Starfish Eggs, Tetrahedron Lett., 34(37), 5935-5938, 19930901
  127. Endogenous Pine-Wood Nematicidal Substances in Pines, Pinus massoniana, P. strobus, and P. palustris, Phytochemistry, 33(6), 1395-1401, 19930801
  128. Biosynthetic Generation of the Species-specific Chirality of Limonene in Mentha spicata and Citrus unshiu, J. Chem. Soc. = Chem. Commun., 1370-1372, 19930501
  129. An Efficient Methods for Following the Enzymic Reactions Involved in Camphor Biosynthesis in Cinnamomum camphora by Use of GC-MS and Regiospecifically Deuteriated Substrate, J. Labelled Compd. Radiopharm., 31(5), 397-402, 19920501
  130. Triterpenoids, Diarylheptanoids and Their Glycosides in the Flowers of Alnus Species, Phytochemistry, 29(11), 3611-3614, 19901101
  131. An Anomaly in the Biosynthesis of (E,E)-Farnesol by the Crude Enzyme System of Pisum sativum, Phytochemistry, 29(11), 3467-3472, 19901101
  132. Synthesis of 4- and 5-Regioselectively Deuteriated Geranyl Diphosphates, J. Chem. Soc. Perkin Trans. 1=, 1811-1814, 19891001
  133. Glycinoprenols: Novel Polyprenols Possessing a Phytyl Residue from the Leaves of Soybean, J. Org. Chem., 54(14), 3390-3393, 19890701
  134. Six Novel Secodammarane-type Triterpenes from Male Flowers of Alnus japonica, Phytochemistry, 27(9), 2915-2920, 19880901
  135. Stereospecific Regulation of in vivo Prenyl Chain Elongation. -Prenylation in Higher Plants-, Journal of Synthetic Organic Chemistry= Japan, 46(1), 12-21, 19880401
  136. Facile and Stereospecific Synthesis of (S)- and (R)-[2-2H]-Isopentenyl Pyrophosphates, J. Chem. Soc. Perkin Trans. 1=, 2845-2848, 19871201
  137. Unusual Chain Elongation at the Reversed Face in the Biosynthesis of (E,E)-Farnesol with the Enzyme System of Pisum sativum, Chem. Lett., 497-500, 19870301
  138. C31-Secodammarane-type Triterpenic Acid, 12-Deoxy Alnustic Acid, from the Female Flowers of Alnus pendula, Phytochemistry, 25(5), 1243-1244, 19860501
  139. The Solvent Effects on the Optical Rotatory Properties of 1,7-Diaryl-5-hydroxy-3-heptanones and Related Compounds, Bull. Chem. Soc. Jpn, 59(4), 1181-1188, 19860401
  140. Triterpenoids from the Female and Male Flowers of Alnus sieboldiana, Phytochemistry, 24(11), 2744-2745, 19851101
  141. The Factors Dominating the Reversal in the Sense of the Optical Rotation of Diarylheptanoids in the Solvents of the Different Nature, Chem. Lett., 1331-1334, 19850901
  142. Absolute Configuration of Platyphylloside and (-)-Centrolobol, Bull. Chem. Soc. Jpn, 58(8), 2423-2424, 19850801
  143. The Structures of Four Diarylheptanoid Glycosides from the Female Flowers of Alnus serrulatoides, J. Chem. Soc. Perkin Trans. 1=, 1635-1642, 19840801
  144. C31-Secodammarane-type Triterpenoid Saponins from the Male Flowers of Alnus pendula, Phytochemistry, 23(6), 1297-1299, 19840601
  145. An X-Ray Crystallographic Study on the Absolute Configuration of Dihydroyashabushiketol and the Solvent-dependence of Its Optical Rotation, Bull. Chem. Soc. Jpn, 56(11), 3353-3357, 19831101
  146. The Structures of Four Novel C31-Secodammarane-type Triterpenoid Saponins from the Female Flowers of Alnus serrulatoides, J. Chem. Soc. Perkin Trans. 1=, 1399-1403, 19820701
  147. The Absolute Configuration of Diarylheptanoid Xyloside, Oregonin, Isolated from the Female Flowers of Alnus serrulatoides, Chem. Lett., 895-898, 19820601

Publications such as books

  1. 1998, Andrimid, an Antimicrobial Substance in the Marine Sponge ┣DBHyatella,(/)-┫DB Produced by an Associated ┣DBVibrio(/)-┫DB Bacterium(共著), Springer-Verlag Tokyo= Sponge Sciences -Multidisciplinary Perspectives, 1998

Invited Lecture, Oral Presentation, Poster Presentation

  1. Biologically Active Compounds Produced by Beetles, Shinji Ohta, 24th Symposium on the Development and Application of Naturally Occurring Drug Materials, 2023/10/15, With Invitation, Japanese, Pharmaceutical Society of Japan, Hiroshima, This presentation summarizes the findings of our research group on the chemical constituents associated with the interaction between beetles and their host plants as well as the chemical constituents produced by beetles.
    Related URL
  2. Biologically active compounds produced by plants and insects, Shinji Ohta, The 66th TEAC 2022 Symposium on the Chemistry of Terpenes, Essential Oils and Aromatics, 2022/11/05, With Invitation, Japanese
  3. Male wing substances acting as sex pheromones in the yellow butterfly Eurema mandarina, Kento Yoshimori, Chika Okuda, Shinji Ohta, Hisashi Omura, 3rd ISCE-APACE Joint Meeting, 2022/03/08, Without Invitation, Japanese, ISCE-APACE, Kuala Lumpur
  4. Neuroprotective activity of new long-chain anacardic acid derivatives, janohigenins, from Ophiopogon japonicus seeds, 2021/10/31, Without Invitation, Japanese
  5. A cyanogenic glucoside, linamarin, regulates differential oviposition on white clover by coliadine butterflies, Colias erate and Eurema mandarina, Toshiki Ohashi, Shinji Ohta, Hisashi Omura, APACE2019, 2019/10, Without Invitation, English
  6. New long-chain anacardic acid derivatives from Ophiopogon japonicus, Manami Takeda, Emi Ohta, Tatsuo Nehira, Hisashi Omura, Shinji Ohta, 2019/09, Without Invitation, Japanese
  7. New sulfated purine alkaloids from the pupal cases of wild bruchid seed beetles, Yuri Uyama, Yui Harauchi, Emi Ohta, Tatsuo Nehira, Hisashi Ômura, Hiroyuki Kawachi, Aya Imamura-Jinda, Shinji Ohta, 2019/09, Without Invitation, Japanese
  8. Four new oligorhamnosylferulate esters isolated from leaves of Ficus nota, Felmer S. Latayada, Mylene M. Uy, Emi Ohta, Shinji Ohta, 1st International Conference in Science and Mathematics (ICSM 2019), 2019/04, Without Invitation, English, International Conference in Science and Mathematics, Philippines
  9. Anticancer property of 3-keto-20,22-dimethyl-20-deoxoscalarin isolated from Philippine marine sponge, Chona Gelani, Mylene Uy, Shinji Ohta, Emi Ohta, The 99th CSJ Annual Meeting, 2019/03, Without Invitation, English, CSJ, Koube
  10. Cyanoglucosides in white clover as oviposition deterrents against Eurema mandarina, H. Omura, T. Ohashi, S. Ohta, 2019/03, Without Invitation, Japanese
  11. New prenylated purine alkaloid glycosides regioselectively sulfated by the wild bruchid beetle Bruchidius dorsalis, Yui Harauchi, Emi Ohta, Kyo Muranaka, Hiroyuki Kawachi, Aya Imamura-Jinda, Tatsuo Nehira, Hisashi Ômura, Shinji Ohta, The 62nd TEAC, 2018/10/14, Without Invitation, Japanese, TEAC, Nagasaki City
  12. New Metabolites Produced by the Wild Bruchid Beetle Sulcobruchus sauteri Infesting the Seed of Caesalpinia decapetala var. japonica, Yui Akihara, Sayuri Kamikawa, Yui Harauchi, Emi Ohta, Tatsuo Nehira, Hisashi Omura, Shinji Ohta, The 60th Symposium on the Chemistry of Natural Products, 2018/09/26, Without Invitation, Japanese, Symposium on the Chemistry of Natural Products, Kurume City
  13. Cytotoxicity of 2-Geranylgeranyl-1,4-hydroquinone Isolated from Philippine Marine Sponge Carteriospongia sp., Chona Gelani, Mylene Uy, Shinji Ohta, Emi Ohta, The 98th CSJ Annual Meeting, 2018/03/20, Without Invitation, English, Chemical Society of Japan, Funabashi
  14. Cytotoxicity of 3-Geranylgeranyl-4-hydroxybenzoic acid Isolated from Philippine Marine Sponge Carteriospongia sp., Chona D. Gelani, Mylene M. Uy, Emi Ohta, Shinji Ohta, ASOMPS XV and 22nd NPSP Annual Convention, 2017/12/06, Without Invitation, English, National Institute of Physics ICSI, Quezon City, Philippines
  15. New metabolites isolated from the pupal case of wild bruchid seed beetles, Yui Harauchi, Kyo Muranaka, Sayuri Kamikawa, Emi Ohta, Tatsuo Nehira, Hisashi Omura, Shinji Ohta, 59th Symposium on the Natural Products, 2017/09/21, Without Invitation, Japanese, Sapporo
  16. New biologically active compounds from the fruits of Ficus nipponica, Yui Akihara, Emi Ohta, Tatsuo Nehira, Hisashi Omura, Shinji Ohta, The 61st Symposium on the Chemistry of Terpenes, Essential Oils and Aromatics, 2017/09/09, Without Invitation, Japanese
  17. Dominance of n-alkanes in cuticular hydrocarbons of lycaenid larvae: chemical insignificance to ants, Yutaro Morozumi, Michihito Watanabe, Shinji Ohta, Hisashi Ômura, 2017 ISCE/APACE, 2017/08/23, Without Invitation, English, ISCE, Kyoto
  18. Glycine betaine as an oviposition stimulant for the common grass yellow butterfly, Eurema mandarina, in Albizia julibrissin, Toshiki Ohashi, Shinji Ohta, Hisashi Ômura, 2017 ISCE/APACE, 2017/08/23, Without Invitation, English, ISCE, Kyoto
  19. Inhibition of Sea Urchin and Starfish Embryonic Development by Hexane Extracts from Five Philippine Marine Sponges, Chona D. Gelani, Mylene M. Uy, Keisuke Yasuda, Emi Ohta, Shinji Ohta, The 7th International Conference for Network for Inter-Asian Chemistry Educators, 2017/07/26, Without Invitation, English, International Conference for Network for Inter-Asian Chemistry Educators, Seoul
  20. New furanoditerpenoids from the pupal case of Sulcobruchus sauteri, Sayuri Kamikawa, Emi Ohta, Tatsuo Nehira, Hisashi Omura, Shinji Ohta, 60th TEAC, 2016/10/29, Without Invitation, Japanese, TEAC
  21. Wistin is a PPARγ agonist that stimulates adipocyte differentiation, Fumiya NAKAMURA, Matoki SANADA, Ryuichi HAYASHI, Yoshimasa IMAI, Tomoyo INOUE, Shinji OHTA, Hiroyuki KAWACHI, 17th AAAP Animal Science Congress, 2016/08/29, Without Invitation, English, AAAP, Fukuoka
  22. Fractionation and identification of 5-nonadecylresorcinol as an agonist of PPAR in soy sauce oil, Yoshimasa IMAI, Yoshihiro Yamada, Matoki SANADA, Fumiya NAKAMURA, Tomoki HAYASHI, Shinji OHTA, Hiroyuki KAWACHI, 17th AAAP Animal Science Congress, 2016/08/23, Without Invitation, English, AAAP, Fukuoka
  23. New cassane-type furanoditerpenoids from Caesalpinia decapetala var. japonica, Shiori Oshimo, Sayuri Kamikawa, Emi Ohta, Tatsuo Nehira, Hisashi Omura, Shinji Ohta, 59th TEAC, 2015/09, Without Invitation, Japanese, TEAC
  24. New bisabolane-type sesquiterpenoids from seeds of Angelica keiskei, Yasunori Yuasa, Emi Ohta, Tatsuo Nehira, Hisashi Omura, Shinji Ohta, 59th TEAC, 2015/09, Without Invitation, Japanese
  25. New sesquiterpenoids from seed coats of Ophiopogon japonicus and their allelopathic effects, Yuya Tsubaki, Emi Ohta, Tatsuo Nehira, Hisashi Omura, Shinji Ohta, 59th TEAC, 2015/09, Without Invitation, Japanese
  26. Antibacterial diterpenoids from Caesalpinia decapetala var. japonica and structure revision of caesaljapin, caesalpinista A, and caesalpinista B, Sayuri Kamikawa, Shiori Oshimo, Emi Ohta, Tatsuo Nehira, HisashiOmura, Shinji Ohta, 57th Symposium on the chemistry of natural products, 2015/09, Without Invitation, Japanese

Social Activities

Organizing Academic Conferences, etc.

  1. 2019/09, 2019/09

History as Peer Reviews of Academic Papers

  1. 2022, Phytochemistry, Others, 10
  2. 2022, Molecules, Others, 3
  3. 2022, Marine Drugs, Others, 2
  4. 2022, Chemistry & Biodiversity, Others, 2
  5. 2022, Heterocycles, Others, 2
  6. 2022, Natural Product Research, Others, 1
  7. 2022, Applied Entomology and Zoology, 1
  8. 2022, International Journal of Molecular Sciences, 1
  9. 2022, Medicinal Chemistry Research, Others, 1
  10. 2022, Food & Function, Others, 1
  11. 2021, Phytochemistry, Others, 3
  12. 2021, Molecules, Others, 3
  13. 2021, Marine Drug, Others, 2
  14. 2021, Pharmaceuticals, Others, 1
  15. 2021, Phytochemistry Letters, Others, 2
  16. 2020, Phytochemistry, Others
  17. 2020, Molecules, Others
  18. 2020, Natural Product Research, Others
  19. 2020, Phytochemistry Letters, Others
  20. 2020, Marine Drugs, Others
  21. 2019, Phytochemistry, Others, 2
  22. 2019, Molecules, 5
  23. 2019, Chemistry and Biodiversity, Others, 1
  24. 2019, Nat Prod Res, Others, 1
  25. 2019, MarineDrugs, Others, 1
  26. 2019, J Nat Prod, Others, 1
  27. 2018, Cur. Bioact. Compd. x2, Others
  28. 2018, Chem. Biodiversity, Others
  29. 2018, Phytochem. Lett., Others
  30. 2018, Stud. Nat. Prod. Chem., Others
  31. 2018, Molecules x4, Others
  32. 2018, Med. Chem. x4, Others
  33. 2018, J. Nat. Prod., Others
  34. 2018, Nat. Prod. Res., Others
  35. 2018, Phytochemistry x3, Others
  36. 2018, Marine Drugs x11, Others
  37. 2018, Antioxidant, Others
  38. 2016, Molecules3, Others
  39. 2016, Molecules2, Others
  40. 2017, Molecules3, Others
  41. 2017, Molecules2, Others
  42. 2017, Journal of Pharmaceutical Sciences and Experimental Pharmacology, Others
  43. 2017, Molecules, Others
  44. 2016, Chemistry Letters, Others
  45. 2016, Phytochemistry Review, Others, Referee, 1
  46. 2016, Natural Product Research, Others, Reviewer, 1
  47. 2016, Molecules, Others, 3
  48. 2016, Planta Medica, Others, 1
  49. 2015, MarineDrugs, Others, 1
  50. 2014, Bioscience, Biotechnology, and Biochemistry
  51. 2014, Journal of Natural Products
  52. 2014, Marine Drugs