西内 由紀子YUKIKO NISHIUCHI

Last Updated :2023/12/04

所属・職名
IDEC国際連携機構　特任准教授
メールアドレス
nishiuchihiroshima-u.ac.jp

基本情報

学位

  • 医学博士　(大阪市立大学)

研究分野

  • 医歯薬学 / 基礎医学 / 細菌学（含真菌学）
  • 医歯薬学 / 内科系臨床医学 / 呼吸器内科学
  • 生物学 / 基礎生物学 / 生態・環境
  • 生物学 / 基礎生物学 / 形態・構造
  • 複合領域 / 生活科学 / 衣・住生活学
  • 総合生物 / ゲノム科学 / ゲノム生物学

研究キーワード

  • 非結核性抗酸菌, 肺MAC症、バイオフィルム形成、環境中分布動態、病原性

研究活動

学術論文（★は代表的な論文）

  1. Unique genomic sequences in novel Mycobacterium avium subsp. hominissuis lineage enabled fine scale tracing the transmission route during pig movement, bioRxiv, 20220404
    DOIを用いた論文検索結果へのリンク
  2. Genomic features of Mycobacterium avium subsp. hominissuis isolated from pigs in Japan, bioRxiv, 20210615
    DOIを用いた論文検索結果へのリンク
  3. Genome-wide association study reveals putative bacterial risk factors for cavitary Mycobacterium avium complex lung disease, bioRxiv, 20210706
    DOIを用いた論文検索結果へのリンク
  4. Structure of bacterial communities in Japanese-style bathrooms: Comparative sequencing of bacteria in shower water and showerhead biofilms using a portable nanopore sequencer, bioRxiv, 20210714
    DOIを用いた論文検索結果へのリンク
  5. Evaluation of IS1245 LAMP in Mycobacterium avium and the influence of host-related genetic diversity on its application, DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 101巻, 4号, 202112
    DOIを用いた論文検索結果へのリンク
  6. Genomic features of Mycobacterium avium subsp. hominissuis isolated from pigs in Japan, Gigabyte, 20210615
    DOIを用いた論文検索結果へのリンク
  7. Ultrastructure of the Mycobacterium avium subsp. hominissuis Biofilm, Microbes and Environments, 36巻, 1号, pp. ME20128, 2021
  8. Diversification of the restriction–modification system of Streptococcus pyogenes through its acquisition of mobile elements, bioRxiv, 20200630
    DOIを用いた論文検索結果へのリンク
  9. Genetic relatedness of Mycobacterium avium subsp. hominissuis isolates from bathrooms of healthy volunteers, rivers, and soils in Japan with human clinical isolates from different geographical areas, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 74巻, pp. 103923-103923, 201910
  10. Population Structure and Local Adaptation of MAC Lung Disease Agent Mycobacterium avium subsp. hominissuis., Genome biology and evolution, 9巻, 9号, pp. 2403-2417, 20170901
  11. Infection Sources of a Common Non-tuberculous Mycobacterial Pathogen, Mycobacterium avium Complex, FRONTIERS IN MEDICINE, 4巻, pp. 27, 20170307
  12. Effects of nutritional and ambient oxygen condition on biofilm formation in Mycobacterium avium subsp. Hominissuis via altered glycolipid expression, Scientific Reports, 7巻, pp. 41775, 20170203
  13. A New Screen for Tuberculosis Drug Candidates Utilizing a Luciferase-Expressing Recombinant Mycobacterium bovis Bacillus Calmette-Gueren, PLOS ONE, 10巻, 11号, pp. e0141658, 201511
  14. 抗酸菌およびそのバイオフィルムに対する次亜塩素酸ナトリウムと二酸化塩素ガス溶存液の殺菌効果, 日本環境感染学会誌, 30巻, 4号, pp. 243-248, 201507
  15. パイやカップ麺に含まれる飽和脂肪酸およびトランス脂肪酸の分析, 神戸松蔭女子学院大学研究紀要, 4巻, pp. 1-9, 201503
  16. Intra-subspecies sequence variability of the MACPPE12 gene in Mycobacterium avium subsp. hominissuis, Infection, Genetics and Evolution, 21巻, pp. 479-483, 201401
  17. Direct detection of Mycobacterium avium in environmental water and scale samples by loop-mediated isothermal amplification, Journal of Water and Health, 12巻, 2号, pp. 211-219, 2014
  18. 管理栄養士養成課程「人体の構造と機能及び疾病の成り立ち」分野での微生物学実験についての一考察, 神戸松蔭女子学院大学 神戸松蔭女子学院大学研究紀要. 人間科学部篇, 2巻, pp. 1-12, 20130305
  19. Critical Roles for Lipomannan and Lipoarabinomannan in Cell Wall Integrity of Mycobacteria and Pathogenesis of Tuberculosis, MBIO, 4巻, 1号, pp. e00472-12, 201301
  20. Whole-genome sequence of the hypervirulent clinical strain Mycobacterium intracellulare M.i.198., Journal of bacteriology, 194巻, 22号, pp. 6336-6336, 201211
  21. Genetic diversity of Mycobacterium avium subsp. hominissuis strains isolated from humans, pigs, and human living environment, Infection, Genetics and Evolution, 12巻, 4号, pp. 846-852, 201206
  22. Descriptive analysis of the prevalence and the molecular epidemiology of Mycobacterium avium complex-infected pigs that were slaughtered on the main island of Okinawa, COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, 33巻, 5号, pp. 401-421, 201009
  23. Serodiagnosis of Pulmonary Disease Due to Mycobacterium avium Complex Proven by Bronchial Wash Culture, CHEST, 138巻, 1号, pp. 236-237, 201007
  24. Mycobacterium kyorinense sp nov., a novel, slow-growing species, related to Mycobacterium celatum, isolated from human clinical specimens, INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 59巻, Pt 6号, pp. 1336-1341, 200906
  25. Mycobacterium avium Complex Organisms Predominantly Colonize in the Bathtub Inlets of Patients' Bathrooms, JAPANESE JOURNAL OF INFECTIOUS DISEASES, 62巻, 3号, pp. 182-186, 200905
  26. ガスクロマトグラフィー/質量分析計を導入した学生実験の試み, 神戸松蔭女子学院大学 生活科学論叢, 40巻, pp. 53-61, 20090310
  27. Virulence of Mycobacterium avium complex strains isolated from immunocompetent patients, MICROBIAL PATHOGENESIS, 46巻, 1号, pp. 6-12, 200901
  28. Control of cell wall assembly by a histone-like protein in mycobacteria, JOURNAL OF BACTERIOLOGY, 189巻, 22号, pp. 8241-8249, 200711
  29. Serological test and chest computed tomography findings in patients with Mycobacterium avium complex lung disease, EUROPEAN RESPIRATORY JOURNAL, 29巻, 6号, pp. 1217-1223, 200706
  30. 肺Mycobacterium avium complex (MAC)症患者の家庭内MAC分布, IFO Research Communications, 21巻, pp. 61-70, 2007
  31. Liquid chromatography/mass spectrometry analysis of small-scale glycopeptidolipid preparations to identify serovars of Mycobacterium avium-intracellulare complex, Journal of Applied Microbiology, 97巻, 4号, pp. 738-748, 2004
  32. Induction of thymic apoptosis by Shiga toxin from Escherichia coli O157:H7 in vivo and in vitro., Osaka City Med. J., 47巻, 1号, pp. 11-22, 2001
  33. Mycolic acids from Rhodococcus, Gordonia, and Dietzia, Journal of Microbiological Methods, 40巻, 1号, pp. 1-9, 200003
  34. Mycolic acid analysis in Nocardia species: The mycolic acid compositions of Nocardia asteroides, N. farcinica, and N. nova, Journal of Microbiological Methods, 37巻, 2号, pp. 111-122, 199908
  35. Composition of mycolic acid molecular species as a criterion in nocardial classification, INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY, 47巻, 3号, pp. 795-801, 199707
  36. Direct involvement of hydrogen peroxide in bacterial α-hydroxylation of fatty acid, FEBS Letters, 386巻, 2-3号, pp. 252-254, 19960520
  37. TRANSFER OF 2 BURKHOLDERIA AND AN ALCALIGENES SPECIES TO RALSTONIA GEN-NOV - PROPOSAL OF RALSTONIA-PICKETTII (RALSTON, PALLERONI AND DOUDOROFF 1973) COMB-NOV, RALSTONIA-SOLANACEARUM (SMITH 1896) COMB-NOV AND RALSTONIA-EUTROPHA (DAVIS 1969) COMB-NOV, MICROBIOLOGY AND IMMUNOLOGY, 39巻, 11号, pp. 897-904, 1995
  38. The utility of 2-hydroxypropyl-β-cyclodextrin as a vehicle for the intracerebral and intrathecal administration of drugs, Life Sciences, 48巻, 7号, pp. 623-633, 1991
  39. INHIBITION BY FORSKOLIN OF EXCITATORY AMINO ACID-INDUCED ACCUMULATION OF CYCLIC-AMP IN GUINEA-PIG HIPPOCAMPAL SLICES, JOURNAL OF NEUROCHEMISTRY, 51巻, 1号, pp. 237-242, 198807
  40. MECHANISM OF EXCITATORY AMINO ACID-INDUCED ACCUMULATION OF CYCLIC-AMP IN HIPPOCAMPAL SLICES - ROLE OF EXTRACELLULAR CHLORIDE, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 245巻, 1号, pp. 299-304, 19880400
  41. Adduct Formation of Delamanid with NAD in Mycobacteria, Antimicrobial agents and chemotherapy, 64巻, 5号, 20200421
  42. A histone-like protein of mycobacteria possesses ferritin superfamily protein-like activity and protects against DNA damage by Fenton reaction, PLoS ONE, 6巻, 6号, pp. e20985, 2011