広島大学

基本情報

学位

• 博士（医学）　(広島大学)

研究分野

• 医歯薬学 / 外科系臨床医学 / 整形外科学

教育活動

授業担当

1. 2025年, 学部専門, 通年, 器官・システム病態制御学II
2. 2025年, 学部専門, 集中, 臨床実習I
3. 2025年, 修士課程・博士課程前期, セメスター（後期）, 臨床医歯学総論

研究活動

学術論文（★は代表的な論文）

1. The ankle instability severity score. A simple preoperative score to select patients for ankle ligament repair or reconstruction Surgery, ORTHOPAEDICS & TRAUMATOLOGY-SURGERY & RESEARCH, 111巻, 4号, 202506
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2. The difference in second-third metatarsal length is associated with the risk of dislocation or arthritic change in the second metatarsophalangeal joint in patients with hallux valgus, JOURNAL OF ORTHOPAEDIC SCIENCE, 30巻, 4号, pp. 640-646, 202507
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3. Clinical significance of posterior talofibular ligament injury in chronic lateral ankle instability, ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, 144巻, 11号, pp. 5021-5030, 202411
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4. Negative impact of increasing age on clinical outcomes of arthroscopic lateral ankle ligament repair for chronic lateral ankle instability, JOURNAL OF EXPERIMENTAL ORTHOPAEDICS, 12巻, 3号, 202507
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5. Subchondral bone conditions influence pain in patients with osteochondral lesion of the talus, ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, 145巻, 1号, 20250609
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6. Optimal Target Angle in Oblique Diaphyseal Osteotomy of the Fifth Metatarsal for Symptomatic Bunionette: A Retrospective Analysis, FOOT & ANKLE INTERNATIONAL, 46巻, 4号, pp. 415-421, 202504
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7. Effects of Silk-Elastin and SpheroSeev Mixture and Minced Cartilage on Cartilage Repair in Rabbit Osteochondral Defect Models, ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE, 13巻, 4号, 202504
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8. CD1530, selective RARγ agonist, facilitates Achilles tendon healing by modulating the healing environment including less chondrification in a mouse model, JOURNAL OF ORTHOPAEDIC RESEARCH, 43巻, 2号, pp. 273-284, 202502
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9. Fixation for osteochondral lesions of the talus leads to successful clinical outcomes in 9 out of 10 patients: A systematic review, JOURNAL OF ISAKOS JOINT DISORDERS & ORTHOPAEDIC SPORTS MEDICINE, 11巻, 202504
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10. Effect of a compression staple on correction of varus deformity during arthroscopic ankle arthrodesis, JOURNAL OF ORTHOPAEDIC SCIENCE, 30巻, 1号, pp. 113-118, 202501
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11. Comparative Retrospective Study of PLLA and PLLA/HA Pins for Osteochondral Fragment Fixation in Osteochondral Lesion of the Talus, FOOT & ANKLE INTERNATIONAL, 46巻, 2号, pp. 175-181, 202502
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12. First-in-human exploratory trial assessing safety, feasibility, and efficacy of artificial protein (silk-elastin) in promoting healing in patients with meniscus injuries, SCIENTIFIC REPORTS, 15巻, 1号, 20250207
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13. Comparison of the distance between the talus and lateral malleolus during the stance phase with and without chronic ankle instability, SCIENTIFIC REPORTS, 14巻, 1号, 20241107
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14. Quantitative evaluation of calcaneofibular ligament injury on the oblique coronal view of magnetic resonance imaging in chronic lateral ankle instability, JOURNAL OF ORTHOPAEDIC SCIENCE, 29巻, 6号, pp. 1456-1461, 202411
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15. The Hounsfield Unit Values of Talar Subchondral Bone Predict Articular Cartilage Degeneration in Patients With Ankle Osteoarthritis, FOOT & ANKLE INTERNATIONAL, 45巻, 11号, pp. 1292-1301, 202411
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16. Development of osteophytes and joint space narrowing is associated with cartilage degeneration of the osteochondral fragment in the osteochondral lesion of the talus, JOURNAL OF ORTHOPAEDIC SCIENCE, 29巻, 5号, pp. 1242-1247, 202409
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17. Morphology and deformity of the distal phalanx in hallux valgus, JOURNAL OF ORTHOPAEDIC SCIENCE, 29巻, 5号, pp. 1265-1269, 202409
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18. The Relationship Between Calcaneofibular Ligament Injury and Ankle Osteoarthritis Progression: A Comprehensive Analysis of Stress Distribution and Osteophyte Formation in the Subtalar Joint, FOOT & ANKLE INTERNATIONAL, 45巻, 8号, pp. 870-878, 202408
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19. Development of a novel approach for restoration of the meniscus using silk-elastin in a rabbit meniscus injury model, BMC MUSCULOSKELETAL DISORDERS, 25巻, 1号, 20240715
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20. High-fat diet-induced obesity accelerates the progression of spontaneous osteoarthritis in senescence-accelerated mouse prone 8, MODERN RHEUMATOLOGY, 34巻, 4号, pp. 831-840, 20230928
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21. Effects of Preoperative Abnormality of Posterior Tibial Tendon on the Surgical Outcomes of Medial Osteochondral Lesion of the Talus, CUREUS JOURNAL OF MEDICAL SCIENCE, 16巻, 6号, 20240610
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22. Correction effects of peroneus longus contraction on hallux valgus radiographic parameters, JOURNAL OF ORTHOPAEDIC SCIENCE, 29巻, 4号, pp. 1026-1030, 202407
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23. Augmentation of the medial collateral ligament using suture tape reduces the recurrence after corrective surgery for severe hallux valgus, JOURNAL OF ORTHOPAEDIC SCIENCE, 29巻, 4号, pp. 1046-1053, 202407
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24. Hounsfield Unit values on the subchondral bone are related to clinical outcomes in bone marrow stimulation for osteochondral lesions of the talus, JOURNAL OF ORTHOPAEDIC SCIENCE, 29巻, 4号, pp. 1097-1102, 202407
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25. First tarsometatarsal joint mobility in hallux valgus during gait: A synchronized ultrasound and three-dimensional motion capture analysis, JOURNAL OF MEDICAL ULTRASONICS, 51巻, 2号, pp. 331-339, 202404
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26. Osteophyte Cartilage as a Potential Source for Minced Cartilage Implantation: A Novel Approach for Articular Cartilage Repair in Osteoarthritis, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 25巻, 10号, 202405
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27. Relationship between foot morphologic characteristic and postural control after jump-landing in youth competitive athletes, JOURNAL OF BACK AND MUSCULOSKELETAL REHABILITATION, 37巻, 2号, pp. 419-426, 2024
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28. Nonunion of Isolated Medial Cuneiform Fracture Fixed With a Compression Screw and Compression Staple: A Case Report, CUREUS JOURNAL OF MEDICAL SCIENCE, 16巻, 4号, 20240411
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29. Reconstruction of the Lateral Collateral Ligament Using a Suture Tape Anchor for Iatrogenic Hallux Varus, CASE REPORTS IN ORTHOPEDICS, 2021巻, 2021
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30. Arthroscopic Fixation Using Bioabsorbable Pins With Bone Grafting via a Medial Malleolus Approach to Treat Osteochondral Lesion of the Talus, FOOT & ANKLE SPECIALIST, 17巻, 1_SUPPL号, pp. 68S-74S, 202402
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31. Comparison of Clinical Outcomes With Arthroscopic ATFL Repair With the CFL Repair and Open ATFL and CFL Repair in Chronic Lateral Ankle Instability, JOURNAL OF FOOT & ANKLE SURGERY, 63巻, 2号, pp. 176-181, 2024
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32. Needle Arthroscopy as a Promising Alternative to MRI for the Diagnosis of Meniscus Injury, CUREUS JOURNAL OF MEDICAL SCIENCE, 15巻, 11号, 20231111
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33. Loosening of the anterolateral capsule affects the stability after arthroscopic lateral ankle ligament repair of chronic ankle instability, ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, 144巻, 1号, pp. 189-196, 202401
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34. Decreased Joint Position Sense of the Ankle Joint Is a Risk Factor for Falls in the Elderly, CUREUS JOURNAL OF MEDICAL SCIENCE, 15巻, 12号, 20231225
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35. Talonavicular Arthrodesis Using a Screw and Compression Staple in a Patient With Bipartite Navicular Bone: A Case Report, CUREUS JOURNAL OF MEDICAL SCIENCE, 15巻, 8号, 20230808
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36. Stepwise decision making for CFL repair in addition to arthroscopic ATFL repair yields good clinical outcomes in chronic lateral ankle instability regardless of the remnant quality, JOURNAL OF ORTHOPAEDIC SCIENCE, 28巻, 5号, pp. 1087-1092, 202309
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37. High incidence of osteoarthritic changes in patients with osteochondral lesions of the talus without chronic lateral ankle instability, JOURNAL OF ORTHOPAEDIC SCIENCE, 29巻, 1号, pp. 249-255, 202401
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38. Relationship between pain and intra-articular pathology in patients with chronic lateral ankle instability, ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, 144巻, 2号, pp. 815-822, 202402
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39. The role of the oblique medial osteotomy angle during osteochondral fragment fixation in patients with a posteromedial osteochondral lesion of the talus, JOURNAL OF ORTHOPAEDIC SCIENCE, 28巻, 5号, pp. 1093-1098, 202309
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40. MRI signal intensity ratio reflects the quality of the anterior talofibular and calcaneofibular ligaments in patients with chronic lateral ankle instability, JOURNAL OF ORTHOPAEDIC SCIENCE, 28巻, 6号, pp. 1331-1336, 202311
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41. Reconstruction of the Articular Surface in the Subtalar Joint by Osteochondral Autologous Transplantation After Failure of Tibiotalocalcaneal Fusion With a Retrograde Nail: A Case Report, CUREUS JOURNAL OF MEDICAL SCIENCE, 15巻, 9号, 20230920
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42. Achilles Tendon Reconstruction Using a Hamstring Tendon Autograft for Chronic Rupture of the Achilles Tendon in Patients Over 70 Years of Age: A Retrospective Case Series, CUREUS JOURNAL OF MEDICAL SCIENCE, 15巻, 8号, 20230801
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43. Feasibility of administration of calcitonin gene-related peptide receptor antagonist on attenuation of pain and progression in osteoarthritis, SCIENTIFIC REPORTS, 13巻, 1号, 20230916
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44. Relationship of Chronic Ankle Instability With Foot Alignment and Dynamic Postural Stability in Adolescent Competitive Athletes, ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE, 11巻, 10号, 202310
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45. The Subchondral Bone Condition During Microfracture Affects the Repair of the Osteochondral Unit in the Cartilage Defect in the Rat Model, AMERICAN JOURNAL OF SPORTS MEDICINE, 51巻, 9号, pp. 2472-2479, 202307
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46. Risk Factors for the Recurrence of Instability After Lateral Ankle Ligament Repair, FOOT & ANKLE INTERNATIONAL, 44巻, 7号, pp. 617-628, 202307
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47. Changes in the Subchondral Bone Affect Pain in the Natural Course of Traumatic Articular Cartilage Defects, CARTILAGE, 14巻, 2号, pp. 247-255, 202306
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48. Human Trials on the Prevention of Tunnel Widening by the Emdogain in Anterior Cruciate Ligament Reconstruction, CUREUS JOURNAL OF MEDICAL SCIENCE, 15巻, 3号, 20230309
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49. Distraction arthroplasty combined with autologous bone grafting for diffuse-type tenosynovial giant cell tumour with articular cartilage defect and subchondral bone cysts: A case report, MODERN RHEUMATOLOGY CASE REPORTS, 7巻, 2号, pp. 483-487, 20230619
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50. miR-26a deficiency is associated with bone loss and reduced muscle strength but does not affect severity of cartilage damage in osteoarthritis, MECHANISMS OF AGEING AND DEVELOPMENT, 212巻, 202306
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51. MRI appearance of the lateral fibulotalocalcaneal ligament complex injury in the patients with chronic lateral ankle instability, FOOT AND ANKLE SURGERY, 28巻, 7号, pp. 968-974, 202210
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52. The role of substance P on maintaining ligament homeostasis by inhibiting endochondral ossification during osteoarthritis progression, CONNECTIVE TISSUE RESEARCH, 64巻, 1号, pp. 82-92, 20230102
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53. miR-23a/b clusters are not essential for the pathogenesis of osteoarthritis in mouse aging and post-traumatic models, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 10巻, 20230104
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54. Radiographic foot alignment and morphological features of deltoid ligament in pediatric patients with medial osteochondral lesions of the talus, JOURNAL OF PEDIATRIC ORTHOPAEDICS-PART B, 32巻, 1号, pp. 39-46, 202301
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55. Senescence-accelerated mice prone 8 (SAMP8) in male as a spontaneous osteoarthritis model, ARTHRITIS RESEARCH & THERAPY, 24巻, 1号, 20221018
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56. Characteristics of Chronic Ankle Instability Requiring Both Anterior Talofibular and Calcaneofibular Ligament Repair, JOURNAL OF FOOT & ANKLE SURGERY, 61巻, 5号, pp. 1028-1033, 2022
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57. Therapeutic effect of targeting Substance P on the progression of osteoarthritis, MODERN RHEUMATOLOGY, 32巻, 6号, pp. 1175-1185, 20221015
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58. Clinical Outcomes of Osteochondral Fragment Fixation Versus Microfracture Even for Small Osteochondral Lesions of the Talus, AMERICAN JOURNAL OF SPORTS MEDICINE, 50巻, 11号, pp. 3019-3027, 202209
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59. Distributional patterns of subchondral bone density and histopathological features of the first tarsometatarsal joint in hallux valgus feet, BMC MUSCULOSKELETAL DISORDERS, 23巻, 1号, 20220614
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60. High-stress distribution in the lateral region of the subtalar joint in the patient with chronic lateral ankle instability, ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, 142巻, 7号, pp. 1579-1587, 202207
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61. Tendon-Specific Dicer Deficient Mice Exhibit Hypoplastic Tendon Through the Downregulation of Tendon-Related Genes and MicroRNAs, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 10巻, 20220614
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62. Characteristic Bone Morphology Change of the Subtalar Joint in Severe Varus Ankle Osteoarthritis, JOURNAL OF FOOT & ANKLE SURGERY, 61巻, 3号, pp. 627-632, 2022
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63. Quantitative evaluation of the vertical mobility of the first tarsometatarsal joint during stance phase of gait, SCIENTIFIC REPORTS, 12巻, 1号, 20220602
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64. An association between excessive valgus hindfoot alignment and postural stability during single-leg standing in adolescent athletes, BMC SPORTS SCIENCE MEDICINE AND REHABILITATION, 14巻, 1号, 20220411
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65. The therapeutic capacity of bone marrow MSC-derived extracellular vesicles in Achilles tendon healing is passage-dependent and indicated by specific glycans, FEBS LETTERS, 596巻, 8号, pp. 1047-1058, 202204
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66. A Comparison of Central Anatomic Single-Bundle Reconstruction and Anatomic Double-Bundle Reconstruction in Anteroposterior and Rotational Knee Stability: Intraoperative Biomechanical Evaluation, JOURNAL OF KNEE SURGERY, 35巻, 03号, pp. 273-279, 202202
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67. Responses of microRNAs 124a and 223 following spinal cord injury in mice., Spinal Cord, 48巻, 3号, pp. 192-6, 20100301
68. Inhibitory effect of microRNA-146 expression on bone destruction in collagen-induced arthritis., Arthritis Rheum, 20110601
69. A mini-review:microRNA in arthritis., Physiol Genomics, 20110501
70. Expression of MicroRNA-146 in rheumatoid arthritis synovial tissue, ARTHRITIS AND RHEUMATISM, 58巻, 5号, pp. 1284-1292, 200805
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71. Silencing microRNA-34a inhibits chondrocyte apoptosis in a rat osteoarthritis model in vitro, RHEUMATOLOGY, 49巻, 11号, pp. 2054-2060, 201011
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72. The effect of microRNA-21 on proliferation and matrix synthesis of chondrocytes embedded in atelocollagen gel, KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, 18巻, 12号, pp. 1679-1684, 201012
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73. MicroRNA-223 expression in neutrophils in the early phase of secondary damage after spinal cord injury, NEUROSCIENCE LETTERS, 492巻, 2号, pp. 114-118, 20110401
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74. A mini-review: microRNA in arthritis, PHYSIOLOGICAL GENOMICS, 43巻, 10号, pp. 566-570, 201105
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75. The Transverse Ligament as a Landmark for Tibial Sagittal Insertions of the Anterior Cruciate Ligament: A Cadaveric Study, ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY, 27巻, 10号, pp. 1395-1399, 201110
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76. The Inhibitory Effect of MicroRNA-146a Expression on Bone Destruction in Collagen-Induced Arthritis, ARTHRITIS AND RHEUMATISM, 63巻, 6号, pp. 1582-1590, 201106
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77. Effects of knee immobilization on morphological changes in the semitendinosus muscle-tendon complex after hamstring harvesting for anterior cruciate ligament reconstruction: evaluation using three-dimensional computed tomography, JOURNAL OF ORTHOPAEDIC SCIENCE, 17巻, 1号, pp. 39-45, 201201
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78. Characteristic shape of the lateral femoral condyle in patients with osteochondritis dissecans accompanied by a discoid lateral meniscus, JOURNAL OF ORTHOPAEDIC SCIENCE, 17巻, 2号, pp. 124-128, 201203
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79. The relationship of anterior and rotatory laxity between surgical navigation and clinical outcome after ACL reconstruction, KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, 20巻, 4号, pp. 778-784, 201204
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80. Clinical Comparisons Between the Transtibial Technique and the Far Anteromedial Portal Technique for Posterolateral Femoral Tunnel Drilling in Anatomic Double-Bundle Anterior Cruciate Ligament Reconstruction, ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY, 28巻, 5号, pp. 658-666, 201205
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81. Changes in microRNA expression in peripheral mononuclear cells according to the progression of osteoarthritis, MODERN RHEUMATOLOGY, 22巻, 3号, pp. 446-457, 201206
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82. Angiogenic microRNA-210 is present in cells surrounding osteonecrosis, JOURNAL OF ORTHOPAEDIC RESEARCH, 30巻, 8号, pp. 1263-1270, 201208
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83. The Effect of Intra-articular Injection of MicroRNA-210 on Ligament Healing in a Rat Model, AMERICAN JOURNAL OF SPORTS MEDICINE, 40巻, 11号, pp. 2470-2478, 201211
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84. Evaluation of Joint Position Sense Measured by Inversion Angle Replication Error in Patients with an Osteochondral Lesion of the Talus, JOURNAL OF FOOT & ANKLE SURGERY, 52巻, 3号, pp. 331-334, 2013
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85. A new distraction arthroplasty device using magnetic force; a cadaveric study, CLINICAL BIOMECHANICS, 28巻, 4号, pp. 423-428, 201304
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86. Treatment of cartilage defects by subchondral drilling combined with covering with atelocollagen membrane induces osteogenesis in a rat model, JOURNAL OF ORTHOPAEDIC SCIENCE, 18巻, 4号, pp. 627-635, 201307
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87. Overexpression of microRNA-223 in rheumatoid arthritis synovium controls osteoclast differentiation, MODERN RHEUMATOLOGY, 23巻, 4号, pp. 674-685, 201307
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88. Strong adhesiveness of a new biodegradable hydrogel glue, LYDEX, for use on articular cartilage, JOURNAL OF APPLIED BIOMATERIALS & FUNCTIONAL MATERIALS, 11巻, 3号, pp. 180-186, 2013
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89. Enhancement of muscle repair using human mesenchymal stem cells with a magnetic targeting system in a subchronic muscle injury model, JOURNAL OF ORTHOPAEDIC SCIENCE, 19巻, 3号, pp. 478-488, 201405
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90. Regenerative medicine in orthopedics using cells, scaffold, and microRNA, JOURNAL OF ORTHOPAEDIC SCIENCE, 19巻, 4号, pp. 521-528, 201407
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91. Administration of MicroRNA-210 Promotes Spinal Cord Regeneration in Mice, SPINE, 39巻, 14号, pp. 1099-1107, 20140615
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92. Unique patellofemoral alignment in a patient with a symptomatic bipartite patella, KNEE, 23巻, 1号, pp. 127-132, 201601
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93. MicroRNAs and Bone Regeneration, Curr Genomics, 16巻, 6号, pp. 441-452
94. Attenuation of cartilage degeneration by calcitonin gene-related peptide receptor antagonist via inhibition of subchondral bone sclerosis in osteoarthritis mice, J Orthop Res, 2015
95. Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1, Arthritis Res Ther, 17巻, pp. 285
96. Combination therapy with intra-articular injection of mesenchymal stem cells and articulated joint distraction for repair of a chronic osteochondral defect in the rabbit, J Orthop Res, 33巻, 10号, pp. 1466-1473
97. Mesenchymal-stem-cell-derived exosomes accelerate skeletal muscle regeneration., FEBS Lett, 589巻, 11号, pp. 1257-1265, 2015
98. The effect of administration of double stranded microRNA-210 on acceleration of Achilles tendon healing in rat model, J Orthop Science, 20巻, 3号, pp. 538-546, 2015
99. Distraction Arthroplasty With Arthroscopic Microfracture in a Patient With Rheumatoid Arthritis of the Ankle Joint, J Foot Ankle Surg, 54巻, 2号, pp. 280-284, 2015
100. Conservative treatment of severe clubfoot using a novel functional dynamic splint
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165. The Benefit of Minced Cartilage Over Isolated Chondrocytes in Atelocollagen Gel on Chondrocyte Proliferation and Migration, CARTILAGE, 12巻, 1号, pp. 93-101, 202101
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166. Safe angles of ATFL and CFL anchor insertion into anatomical attachment of fibula in a lateral ankle ligament repair, JOURNAL OF ORTHOPAEDIC SCIENCE, 26巻, 1号, pp. 156-161, 202101
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169. Evaluation of the degenerative pattern of PCL in osteoarthritis patients using UTE-T2 mapping, ASIA-PACIFIC JOURNAL OF SPORT MEDICINE ARTHROSCOPY REHABILITATION AND TECHNOLOGY, 24巻, pp. 35-40, 202104
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