岸本 真治SHINJI KISHIMOTO

Last Updated :2025/06/16

所属・職名
原爆放射線医科学研究所 助教
メールアドレス
skishimotohiroshima-u.ac.jp
自己紹介
動脈硬化を中心に臨床、研究を行っています。特に高血圧(原因の明らかな2次性高血圧を含めて)を専門としております。

基本情報

学歴

  • 広島大学, 大学院医歯薬保健学研究科, 医歯薬学専攻 博士課程, 日本, 2014年01月, 2018年03月
  • 広島大学, 医学部, 医学科, 日本, 2003年04月, 2009年03月

学位

  • 博士(医学) (広島大学)

所属学会

  • 日本血管不全学会
  • 日本心臓リハビリテーション学会
  • 日本動脈硬化学会
  • 日本心血管インターベンション治療学会
  • 日本高血圧学会
  • 日本心臓病学会
  • 日本循環器学会
  • 日本内科学会

教育活動

授業担当

  1. 2025年, 学部専門, 集中, 医学研究実習

研究活動

学術論文(★は代表的な論文)

  1. Long-term effects of ipragliflozin on blood pressure in patients with type 2 diabetes: insights from the randomized PROTECT trial, HYPERTENSION RESEARCH, 47巻, 1号, pp. 168-176, 202401
  2. Effects of Cumulative Low-Density Lipoprotein Cholesterol Exposure on Endothelial Function in Subjects Receiving Lipid-Lowering Drugs, JACC-ASIA, 5巻, 5号, pp. 691-694, 202505
  3. Low-intensity pulsed ultrasound improves symptoms in patients with Buerger disease: a double-blinded, randomized, and placebo-controlled study, SCIENTIFIC REPORTS, 14巻, 1号, 20240614
  4. Nighttime blood pressure-targeted antihypertensive treatment, JOURNAL OF HYPERTENSION, 43巻, 5号, pp. 887-896, 202505
  5. Effects of low-intensity pulsed ultrasound on clinical parameters in atherosclerotic peripheral artery disease patients with chronic limb-threatening ischemia, SCIENTIFIC REPORTS, 15巻, 1号, 20250401
  6. The relationship between continuation of exercise habit for three years and endothelial function in patients with hypertension, HYPERTENSION RESEARCH, 48巻, 3号, pp. 927-938, 202503
  7. A Body Shape Index as a Simple Anthropometric Marker for the Risk of Cardiovascular Events, CURRENT CARDIOLOGY REPORTS, 27巻, 1号, 202512
  8. Serum uric acid is independently associated with impaired nitroglycerine-induced vasodilation of the brachial artery in women, HYPERTENSION RESEARCH, 48巻, 1号, pp. 6-14, 202501
  9. Vascular function assessed by flow-mediated vasodilation and nitroglycerine-induced vasodilation in subjects with first-degree atrioventricular block, SCIENTIFIC REPORTS, 14巻, 1号, 20241205
  10. A Body Shape Index as a Simple Anthropometric Marker of Abdominal Obesity and Risk of Cardiovascular Events, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 109巻, 12号, pp. 3272-3281, 20240508
  11. New device for assessment of endothelial function: plethysmographic flow-mediated vasodilation (pFMD), HYPERTENSION RESEARCH, 47巻, 9号, pp. 2471-2477, 202409
  12. Upstroke time is a more useful marker of atherosclerosis than percentage of mean arterial pressure for detecting coronary artery disease in subjects with a normal ankle-brachial index, HYPERTENSION RESEARCH, 47巻, 8号, pp. 2009-2018, 202408
  13. Effects of BNT162b2 mRNA Covid-19 vaccine on vascular function, PLOS ONE, 19巻, 4号, 20240430
  14. Association of cumulative low-density lipoprotein cholesterol exposure with vascular function, JOURNAL OF CLINICAL LIPIDOLOGY, 18巻, 2号, pp. e238-e250, 2024
  15. Seasonal variations in endothelium-dependent flow-mediated vasodilation and endothelium-independent nitroglycerine-induced vasodilation, HYPERTENSION RESEARCH, 47巻, 4号, pp. 910-920, 202404
  16. Role of Small Dense Low-density Lipoprotein Cholesterol in Cardiovascular Events in Patients with Coronary Artery Disease and Type 2 Diabetes Mellitus Receiving Statin Treatment, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 31巻, 4号, pp. 478-500, 2024
  17. Percentage of mean arterial pressure as a marker of atherosclerosis for detecting patients with coronary artery disease, HYPERTENSION RESEARCH, 47巻, 2号, pp. 281-290, 202402
  18. Endothelial Function Is Preserved in Patients with Wild-Type Transthyretin Amyloid Cardiomyopathy, JOURNAL OF CLINICAL MEDICINE, 12巻, 7号, 202304
  19. Impact of overnight 1 mg dexamethasone on vascular function in patients with nonfunctioning adrenal adenomas, SCIENTIFIC REPORTS, 13巻, 1号, 20231128
  20. An Extended Follow-Up on Blood Pressure in a Patient With New-Onset Essential Hypertension: Early-Morning Home, Morning Home, and Office Readings, CUREUS JOURNAL OF MEDICAL SCIENCE, 16巻, 1号, 20240118
  21. Therapeutic Myogenesis Induced by Ultrasound Exposure in a Volumetric Skeletal Muscle Loss Injury Model, AMERICAN JOURNAL OF SPORTS MEDICINE, 51巻, 13号, pp. 3554-3566, 202311
  22. KCNJ5mutation is a predictor for recovery of endothelial function after adrenalectomy in patients with aldosterone-producing adenoma, HYPERTENSION RESEARCH, 46巻, 9号, pp. 2213-2227, 202309
  23. Genetic Risk of Primary Aldosteronism and Its Contribution to Hypertension: A Cross-Ancestry Meta-Analysis of Genome-Wide Association Studies, CIRCULATION, 147巻, 14号, pp. 1097-1109, 20230404
  24. Lack of impact of ipragliflozin on endothelial function in patients with type 2 diabetes: sub-analysis of the PROTECT study, CARDIOVASCULAR DIABETOLOGY, 22巻, 1号, 20230520
  25. Endothelial Function Is Preserved in Patients with Wild-Type Transthyretin Amyloid Cardiomyopathy, Journal of Clinical Medicine, 12巻, 7号, pp. 2534, 20230327
  26. Effect of ipragliflozin on carotid intima-media thickness in patients with type 2 diabetes: a multicenter, randomized, controlled trial, European Heart Journal Cardiovascular Pharmacotherapy, 9巻, 2号, pp. 165-172, 20230202
  27. Effect of exposure to radiation caused by an atomic bomb on endothelial function in atomic bomb survivors, FRONTIERS IN CARDIOVASCULAR MEDICINE, 10巻, 20230217
  28. The prevalence of cardiovascular disease is higher in patients with bilateral low ankle-brachial index than in patients with unilateral low ankle-brachial index, ATHEROSCLEROSIS, 360巻, pp. 8-14, 202211
  29. Serum Potassium Levels of 4.5 to Less Than 5.0 mmol/L Are Associated with Better Vascular Function, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 29巻, 11号, pp. 1588-1602, 2022
  30. Relationship of Daily Coffee Intake with Vascular Function in Patients with Hypertension, NUTRIENTS, 14巻, 13号, 202207
  31. White blood cell count is not associated with flow-mediated vasodilation or nitroglycerine-induced vasodilation, SCIENTIFIC REPORTS, 12巻, 1号, 20220517
  32. Relationship between hemoglobin A1c level and flow-mediated vasodilation in patients with type 2 diabetes mellitus receiving antidiabetic drugs, JOURNAL OF DIABETES INVESTIGATION, 13巻, 4号, pp. 677-686, 202204
  33. Self-reported total sitting time on a non-working day is associated with blunted flow-mediated vasodilation and blunted nitroglycerine-induced vasodilation, SCIENTIFIC REPORTS, 12巻, 1号, 20220416
  34. Implantation of Hypoxia-Induced Mesenchymal Stem Cell Advances Therapeutic Angiogenesis, STEM CELLS INTERNATIONAL, 2022巻, 20220320
  35. Isolated diastolic hypertension is not associated with endothelial dysfunction, HYPERTENSION RESEARCH, 45巻, 4号, pp. 698-707, 202204
  36. Poor tooth brushing behavior is associated with high risk of cardiovascular events: A prospective observational study, INTERNATIONAL JOURNAL OF CARDIOLOGY, 350巻, pp. 111-117, 20220301
  37. Inconvenient relationship of haemoglobin A1c level with endothelial function in type 2 diabetes in a cross-sectional study, BMJ OPEN, 11巻, 6号, 202106
  38. Comparison of gender-specific mortality in patients < 70 years versus ≥ 70 years old with acute myocardial infarction., The American Journal of Cardiology, 108巻, 6号, pp. 772-775, 20110915
  39. Coronary angioscopic findings 9 months after everolimus-eluting stent implantation compared with sirolimus-eluting stents, Journal of Cardiology, 61巻, 1号, pp. 22-30, 201301
  40. Longitudinal extent of lipid pool assessed by optical coherence tomography predicts microvascular no-reflow after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction., Journal of Cardiology, 62巻, 2号, pp. 71-76, 201308
  41. Reduction in blood pressure improves impaired nitroglycerine-induced vasodilation in patients with essential hypertension., Hypertension Research, 38巻, 12号, pp. 862-868, 20150903
  42. Common Variant Near HEY2 Has a Protective Effect on Ventricular Fibrillation Occurrence in Brugada Syndrome by Regulating the Repolarization Current., Circulation Arrhythmia and Electrophysiology, 9巻, 1号, pp. e003436, 201601
  43. Combination of Flow-Mediated Vasodilation and Nitroglycerine-Induced Vasodilation Is More Effective for Prediction of Cardiovascular Events., Hypertension, 67巻, 5号, pp. 1045-1052, 201604
  44. Relationship between serum triglyceride levels and endothelial function in a large community-based study., Atherosclerosis, 247巻, pp. 70-75, 201606
  45. Nitroglycerine-induced vasodilation in coronary and brachial arteries in patients with suspected coronary artery disease., International Journal of Cardiology, 219巻, 15号, pp. 312-316, 20160915
  46. Circulating level of pigment epithelium-derived factor is associated with vascular function and structure: A cross-sectional study., International Journal of Cardiology, 225巻, pp. 91-95, 20161015
  47. Vascular Function and Intima-media Thickness of a Leg Artery in Peripheral Artery Disease: A Comparison of Buerger Disease and Atherosclerotic Peripheral Artery Disease., Journal of Atherosclerosis and Thrombosis, 23巻, 11号, pp. 1261-1269, 201611
  48. Endothelial Function Assessed by Automatic Measurement of Enclosed Zone Flow-Mediated Vasodilation Using an Oscillometric Method Is an Independent Predictor of Cardiovascular Events., Journal of the American Heart Association, 5巻, 12号, pp. e004385, 201610
  49. Endothelial function is impaired in relation to alcohol intake even in the case of light alcohol consumption in Asian men; Flow-mediated Dilation Japan (FMD-J) Study., International Journal of Cardiology, 230巻, pp. 523-528, 201703
  50. Endothelial dysfunction and abnormal vascular structure are simultaneously present in patients with heart failure with preserved ejection fraction, International Journal of Cardiology, 231巻, pp. 181-187, 201703
  51. Increasing Risk of Osteoporotic Fracture Is Associated With Vascular Dysfunction and Abnormal Vascular Structure in Both Men and Women., Circulation Journal, 81巻, 6号, pp. 786-787, 201705
  52. Decreased frequency and duration of tooth brushing is a risk factor for endothelial dysfunction., International Journal of Cardiology, 241巻, pp. 30-34, 201708
  53. Relation of the Bilateral Earlobe Crease to Endothelial Dysfunction., The American Journal of Cardiology, 119巻, 12号, pp. 1983-1988, 201706
  54. α-Glucosidase inhibitor miglitol attenuates glucose fluctuation, heart rate variability and sympathetic activity in patients with type 2 diabetes and acute coronary syndrome: a multicenter randomized controlled (MACS) study., Cardiovasc Diabetol, 16巻, 1号, pp. 86, 201706
  55. Endothelial Function Is Impaired in Patients Receiving Antihypertensive Drug Treatment Regardless of Blood Pressure Level: FMD-J Study (Flow-Mediated Dilation Japan)., Hypertension, 70巻, 4号, pp. 790-797, 201710
  56. Optimal Target Level of Low-density Lipoprotein Cholesterol for Vascular Function in Statin Naïve Individuals., Scientific Reports, 7巻, 1号, pp. 8422, 201708
  57. Brachial artery diameter as a marker for cardiovascular risk assessment: FMD-J study., Atherosclerosis, 268巻, pp. 92-98, 201801
  58. Interrelationships Among Flow-Mediated Vasodilation, Nitroglycerine-Induced Vasodilation, Baseline Brachial Artery Diameter, Hyperemic Shear Stress, and Cardiovascular Risk Factors., Journal of the American Heart Association, 7巻, 1号, pp. e006797, 201801
  59. Coffee with a high content of chlorogenic acids and low content of hydroxyhydroquinone improves postprandial endothelial dysfunction in patients with borderline and stage 1 hypertension., European Journal of Nutrition, 201801
  60. Chronic kidney disease is associated with vascular smooth muscle dysfunction but not with endothelial dysfunction., International Journal of Cardiology, 254巻, pp. 284-290, 201803
  61. Reactive hyperemia-peripheral arterial tonometry is useful for assessment of not only endothelial function but also stenosis of the digital artery., International Journal of Cardiology Volume 260, 1 June 2018, Pages 178-183, 260巻, pp. 178-183, 201806
  62. Endothelial dysfunction, abnormal vascular structure and lower urinary tract symptoms in men and women., International Journal of Cardiology, 261巻, pp. 196-203, 201806
  63. New assessment of endothelial function measured by short time flow-mediated vasodilation: Comparison with conventional flow-mediated vasodilation measurement., International Journal of Cardiology, 265巻, pp. 24-29, 201808
  64. Assessment of Lower-limb Vascular Endothelial Function Based on Enclosed Zone Flow-mediated Dilation., Scientific Reoports, 18巻, 1号, pp. 9263, 201806
  65. Endothelial Dysfunction, Increased Arterial Stiffness, and Cardiovascular Risk Prediction in Patients With Coronary Artery Disease: FMD-J (Flow-Mediated Dilation Japan) Study A., Journal of the American Heart Association, 7巻, 14号, pp. e008588, 201807
  66. Microvascular endothelial function is impaired in patients with idiopathic hyperaldosteronism., Hypertension Research, 201809
  67. Microvascular endothelial function is impaired in patients with idiopathic hyperaldosteronism, HYPERTENSION RESEARCH, 41巻, 11号, pp. 932-938, 201811
  68. Review of the Long-term Effects of Autologous Bone-Marrow Mononuclear Cell Implantation on Clinical Outcomes in Patients with Critical Limb Ischemia, SCIENTIFIC REPORTS, 9巻, 20190522
  69. Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study, JOURNAL OF HYPERTENSION, 37巻, 5号, pp. 1083-1095, 201905
  70. Effect of Saxagliptin on Endothelial Function in Patients with Type 2 Diabetes: A Prospective Multicenter Study, SCIENTIFIC REPORTS, 9巻, 20190715
  71. Relationship between home blood pressure and vascular function in patients receiving antihypertensive drug treatment, HYPERTENSION RESEARCH, 42巻, 8号, pp. 1175-1185, 201908
  72. Relationships Between Calcium Channel Blockers and Vascular Function Tests, AMERICAN JOURNAL OF HYPERTENSION, 32巻, 7号, pp. 640-648, 201907
  73. Effects of the Dipeptidyl Peptidase 4 Inhibitor Alogliptin on Blood Pressure in Hypertensive Patients with Type 2 Diabetes Mellitus, AMERICAN JOURNAL OF HYPERTENSION, 32巻, 7号, pp. 695-702, 201907
  74. Association of extremely high levels of high-density lipoprotein cholesterol with endothelial dysfunction in men, JOURNAL OF CLINICAL LIPIDOLOGY, 13巻, 4号, pp. 664-672, 201908
  75. Elevated Plasma Renin Activity Caused by Accelerated-malignant Hypertension in a Patient with Aldosterone-producing Adenoma Complicated with Renal Insufficiency, INTERNAL MEDICINE, 58巻, 21号, pp. 3107-3111, 2019
  76. Diagnostic Criteria of Flow-Mediated Vasodilation for Normal Endothelial Function and Nitroglycerin-Induced Vasodilation for Normal Vascular Smooth Muscle Function of the Brachial Artery, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 9巻, 2号, 20200121
  77. Long-Term Clinical Outcomes of Autologous Bone Marrow Mononuclear Cell Implantation in Patients With Severe Thromboangiitis Obliterans, CIRCULATION JOURNAL, 84巻, 4号, pp. 650-655, 202004
  78. Non-Invasive Central Venous Pressure Measurement Using Enclosed-Zone Central Venous Pressure (ezCVP (TM)), CIRCULATION JOURNAL, 84巻, 7号, pp. 1112-1117, 202007
  79. Increased arterial stiffness and cardiovascular risk prediction in controlled hypertensive patients with coronary artery disease: post hoc analysis of FMD-J (Flow-mediated Dilation Japan) Study A, HYPERTENSION RESEARCH, 43巻, 8号, pp. 781-790, 202008
  80. Hematocrit, hemoglobin and red blood cells are associated with vascular function and vascular structure in men, SCIENTIFIC REPORTS, 10巻, 1号, 20200710
  81. Target of Triglycerides as Residual Risk for Cardiovascular Events in Patients With Coronary Artery Disease - Post Hoc Analysis of the FMD-J Study A, Circulation Journal, 83巻, 5号, pp. 1064-1071, 201904
  82. Vascular function is further impaired in subjects aged 80 years or older, HYPERTENSION RESEARCH, 43巻, 9号, pp. 914-921, 202009
  83. Relationship between high-density lipoprotein cholesterol levels and endothelial function in women: a cross-sectional study, BMJ OPEN, 10巻, 7号, 2020
  84. Pre-impaired fasting glucose state is a risk factor for endothelial dysfunction: Flow-mediated Dilation Japan (FMD-J) study, BMJ OPEN DIABETES RESEARCH & CARE, 8巻, 1号, 2020
  85. Daily Low-intensity Pulsed Ultrasound Ameliorates Renal Fibrosis and Inflammation in Experimental Hypertensive and Diabetic Nephropathy, HYPERTENSION, 76巻, 6号, pp. 1906-1914, 202012
  86. A Comparison of Adrenalectomy and Eplerenone on Vascular Function in Patients with Aldosterone-producing Adenoma, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 105巻, 11号, 202011
  87. Relationship between cell number and clinical outcomes of autologous bone-marrow mononuclear cell implantation in critical limb ischemia, SCIENTIFIC REPORTS, 10巻, 1号, 20201116
  88. Endothelial function is preserved in light to moderate alcohol drinkers but is impaired in heavy drinkers in women: Flow-mediated Dilation Japan (FMD-J) study, PLOS ONE, 15巻, 12号, 20201203
  89. Low Levels of Low-Density Lipoprotein Cholesterol and Endothelial Function in Subjects without Lipid-Lowering Therapy, JOURNAL OF CLINICAL MEDICINE, 9巻, 12号, 202012
  90. Association of Body Mass Index with Endothelial Function in Asian Men, INTERNATIONAL JOURNAL OF CARDIOLOGY, 324巻, pp. 186-192, 20210201
  91. Smoking status and endothelial function in Japanese men, SCIENTIFIC REPORTS, 11巻, 1号, 20210108
  92. Upstroke Time Is a Useful Vascular Marker for Detecting Patients With Coronary Artery Disease Among Subjects With Normal Ankle-Brachial Index, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 9巻, 23号, 20201201
  93. Finger blood flow after the cold challenge with primary Raynaud's syndrome: a case report, EUROPEAN HEART JOURNAL-CASE REPORTS, 4巻, 6号, 202012
  94. Lower triglyceride levels are associated with better endothelial function, JOURNAL OF CLINICAL LIPIDOLOGY, 15巻, 3号, pp. 500-511, 2021
  95. Low-intensity pulsed ultrasound decreases major amputation in patients with critical limb ischemia: 5-year follow-up study, PLOS ONE, 16巻, 8号, 2021
  96. Volume Elastic Modulus, Vascular Function, and Vascular Structure in Patients with Cardiovascular Risk Factors, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 28巻, 9号, pp. 963-973, 2021
  97. A body shape index is associated with endothelial dysfunction in both men and women, SCIENTIFIC REPORTS, 11巻, 1号, 20210909
  98. Regenerative medicine for radiation emergencies, JOURNAL OF RADIATION RESEARCH, 62巻, pp. I21-I29, 202104
  99. Stair climbing activity and vascular function in patients with hypertension, HYPERTENSION RESEARCH, 44巻, 10号, pp. 1274-1282, 202110
  100. Asymptomatic coronary aneurysms in a patient with eosinophilic granulomatosis with polyangiitis who developed a digital gangrene, MODERN RHEUMATOLOGY CASE REPORTS, 5巻, 1号, pp. 130-136, 20210102
  101. Upstroke time as a marker of atherosclerosis in patients with diabetes mellitus who have a normal ankle-brachial index, JOURNAL OF DIABETES AND ITS COMPLICATIONS, 35巻, 11号, 202111
  102. Falsely normalized ankle-brachial index despite the presence of lower-extremity peripheral artery disease: two case reports, JOURNAL OF MEDICAL CASE REPORTS, 15巻, 1号, 20211217
  103. Vascular Dysfunction Predicts Future Deterioration of Left Ventricular Ejection Fraction in Patients with Heart Failure with Mildly Reduced Ejection Fraction, JOURNAL OF CLINICAL MEDICINE, 10巻, 24号, 202112
  104. Short stature is associated with low flow-mediated vasodilation in Japanese men, HYPERTENSION RESEARCH, 45巻, 2号, pp. 308-314, 202202

著書等出版物

  1. 2020年, 循環器疾患とビッグデータ・AI 心不全とビッグデータ, 心不全とビッグデータ, 科学評論社, 2020年, 7/28, その他, 共著, 岸本真治、東幸仁

招待講演、口頭・ポスター発表等

  1. 低周波超音波照射(LIPUS)により救肢しえた治療抵抗性重症虚血肢を有するバージャー病の1例, 斎藤勇介、岸本 真治、丸橋 達也、梶川 正人、溝渕 亜矢、原田 崇弘、山路 貴之、中野 由紀子、Farina Mohamad Yusoff、東 幸仁, 第125回日本循環器学会中国地方会, 2024年11月30日, 通常, 日本語
  2. High ABSI is associated with elevated risk of cardiovascular events, Masato Kajikawa,Shinji Kishimoto, Tatsuya Maruhashi, Aya Mizobuchi, Takahiro Harada, Takayuki Yamaji, Yukiko Nakano, Farina Mohamad Yusoff, Tomohiko Yada, Tomomasa Itarashiki, Yukihito Higashi., 100th Scientific Sessions, American Heart Association Scientific Sessions 2024, 2024年11月18日, 通常, 英語
  3. A Novel Tool for Evaluating Endothelial Function: Plethysmographic Flow-mediated Vasodilation (pFMD), Shinji Kishimoto, Tatsuya Maruhashi, Masato Kajikawa, Aya Mizobuchi, Takahiro Harada, Takayuki Yamaji, Yukiko Nakano, Farina Mohamad Yusoff, Tomohiko Yada, Tomomasa Itarashiki, Yukihito Higashi, American Heart Association Scientific Sessions 2024, 2024年11月18日, 通常, 英語
  4. Association of Cumulative Low-density Lipoprotein Cholesterol Exposure with Atherosclerosis, Takayuki Yamaji, Shinji Kishimoto, Yukihito Higashi, Farina Mohamad Yusoff, Masato Kajikawa, Tatsuya Maruhashi, Yukiko Nakano., ESC Congress 2024, 2024年10月31日, 通常, 英語
  5. Therapeutic effects of low intensity pulsed ultrasound (LIPUS) on myogenesis in a volumetric skeletal muscle loss injury model, Farina Mohamad Yusoff, Shinji Kishimoto, Tatsuya Maruhashi, Masato Kajikawa, Aya Mizobuchi, Takahiro Harada, Takayuki Yamaji, Yukiko Nakano,Yukihito Higashi., The 8th international symposium of the network-type joint usage/research center ofr radiation disaster medical science, 2024年02月15日, 通常, 英語
  6. 累積LDLコレストロールと動脈硬化の進行についての検討, 山路 貴之、岸本 真治、丸橋 達也、梶川 正人、溝渕 亜矢、原田 崇弘、中野 由紀子、Farina Mohamad Yusoff、東 幸仁, 第56回日本動脈硬化学会学術集会, 2024年07月06日, 通常, 日本語
  7. 両側副腎アルドステロン産生腺腫に対して、左副腎全摘出、右副腎部分摘出術にて完治した1例, 岸本真治、東幸仁、山路貴之、梶川正人、丸橋達也、中野由紀子, 第124回日本循環器学会 中国四国合同地方会, 2024年06月22日, 通常, 日本語
  8. 季節および外気温が血管機能に及ぼす影響について, 丸橋達也、梶川正人、岸本真治、溝渕 亜矢、原田 崇弘、山路 貴之、中野 由紀子、Farina Mohamad Yusoff、岩永 義高、金岡 幸嗣郎、矢田 智彦、板良敷 朝将、東 幸仁, 第9回日本血管不全学会学術集会・総会, 2024年04月21日, 通常, 日本語
  9. 冠動脈疾患患者におけるコルヒチンの血管内皮機能に対する有効性, 梶川正人、丸橋達也、岸本真治、溝渕 亜矢、原田 崇弘、山路 貴之、中野 由紀子、Farina Mohamad Yusoff、東 幸仁, 第9回日本血管不全学会学術集会, 2024年04月21日, 通常, 日本語
  10. 高血圧患者におけるコーヒー摂取:血管機能に与える影響について, 山路貴之、梶川正人、中野由紀子、斎藤雄介、溝渕亜矢、原田崇弘、Farina mohamad yosoff、岸本真治、丸橋達也、東幸仁, 第53回日本心脈管作動物質学会, 2024年02月10日, 通常, 日本語
  11. KCNJ5 Mutation Is a Predictor of Endothelial Function Recovery after Adrenalectomy in Aldosterone-producing Adenoma Patients, Shinji Kishimoto, Yukihito Higashi, Takayuki Yamaji, Farina Mohamad Yusoff, Masato Kajikawa, Tatsuya Maruhashi, Yukiko Nakano, 第88回日本循環器病学会総会, 2024年03月08日, 通常, 英語
  12. 血管内皮機能評価のための新しい測定装置, 岸本 真治、丸橋 達也、梶川 正人、溝渕 亜矢、原田 崇弘、山路 貴之、中野 由紀子、Farina Mohamad Yusoff、岩永 義高、金岡 幸嗣郎、矢田 智彦、板良敷 朝将、東 幸仁1, 第53回日本心脈管作動物質学会年会, 2024年02月05日, 通常, 日本語
  13. Low-intensity pulsed ultrasound improves symptoms in peripheral arterial disease: a double-blinded, randomized, and placebo-controlled study, Farina binti mohamad Yusoff, Ayumu Nakashima, Ki-ichiro Kawano, Masato Kajikawa, Shinji Kishimoto, Tatsuya Maruhashi Naoki Ishiuchi, S. Fadilah S. Abdul Wahid and Yukihito Higashi, The Vascular Scientific Sessions presented by Society for Vascular Medicine. 2023 Anual Scientific Sessions, 2023年09月08日, 通常, 英語
  14. 野生型トランスサイレチンアミロイドーシス患者の血管内皮機能は維持されている, 橋本 悠、丸橋 達也、梶川 正人、岸本 真治、原田 崇弘、溝渕 亜矢、Farina Mohamad Yusoff、中野 由紀子、東 幸仁, 第121回日本循環器学会中国地方会, 2022年11月26日, 通常, 日本語
  15. Body Mass Index (BMI)と血管内皮機能との関係, 梶川 正人、丸橋 達也、岸本 真治、原田 崇弘、溝渕 亜矢、橋本 悠、Farina Mohamad Yusoff、中野 由紀子、東 幸仁, 第7回日本血管不全学会学術集会・総会, 2022年04月17日, 通常, 日本語
  16. ABI正常の糖尿病患者におけるupstroke timeと心血管疾患の関係についての検討, 丸橋 達也、梶川 正人、岸本 真治、原田 崇弘、溝渕 亜矢、橋本 悠、Farina Mohamad Yusoff、中野 由紀子、東 幸仁, 第7回日本血管不全学会学術集会・総会, 2022年04月17日, 通常, 日本語
  17. Association between Upstroke Time at the Subjects with Normal Ankle-brachial Index, Tatsuya Maruhashi, Masato Kajikawa, Shinji Kishimoto, Aya Mizobuchi, Takahiro Harada, Yu Hashimoto, Yukiko Nakano, Farina Mohamad Yusoff, Ayumu Nakashima, Yukihito Higashi,, 第86回日本循環器学会学術集会, 2022年03月13日, 通常, 英語
  18. Relationship between a Body Shape Index and Endothelial Function: FMD-Japan Resistry, Masato Kajikawa,Tatsuya Maruhashi, Shinji Kishimoto, Aya Mizobuchi, Takahiro Harada, Yu Hashimoto, Yukiko Nakano, Farina Mohamad Yusoff, Ayumu Nakashima, Yukihito Higashi,, 第86回日本循環器学会学術集会, 2022年03月13日, 通常, 日本語
  19. 職業運転手における睡眠呼吸障害の頻度に関する検討, 丸橋 達也、小川 匡彦、福永 保夫、北浦 大作、梶川 正人、岸本 真治、原田崇弘、溝渕 亜矢、橋本 悠、Farina Mohamad Yusoff、中島 歩、中野 由紀子、東 幸仁, 第43回日本高血圧学会総会, 2021年10月17日, 通常, 日本語
  20. 2022年10月02日, 通常, 英語
  21. 2022年08月09日, 通常, 英語
  22. 2022年02月07日, 通常, 英語
  23. 2022年02月07日, 通常, 英語
  24. 2022年10月14日, 通常, 英語
  25. 2022年10月14日, 通常, 英語
  26. 血管機能はHFmrEFの心機能低下を予測しうる, 岸本 真治、丸橋 達也、梶川 正人、原田崇弘、溝渕 亜矢、橋本 悠、Farina Mohamad Yusoff、中野 由紀子、東 幸仁, 第70回日本心臓病学会学術集会, 2022年09月24日, 通常, 日本語
  27. 2022年10月14日, 通常, 英語
  28. A Study to Compare the Effects of Adrenalectomy and Eplerenone on Vascular Function in Patients with Aldosterone-producing Adenoma, Shinji Kishimoto, Yukihito Higashi, Yu Hashimoto, Takahiro Harada, Takayuki Yamaji, Yuji Takaeko, Farina Mohamad Yusoff, Masato Kajikawa, Tatsuya Maruhashi, Yukiko Nakano, The 85th Annual Scientific Meeting of The Japanese Circulation Society : JCS 2021, 2021年03月26日, 通常, 英語
  29. 男性におけるヘマトクリットと 血管機能・血管構造との関係, 岸本真治 、橋本悠、溝渕亜矢、韓一鳴、山路貴之、原田崇弘、 Farina Mohamad Yusoff、梶川正人、丸橋達也、中野由紀子、東幸仁, 第74回日本酸化ストレス学会、第21回日本NO学会 合同学術集会, 2021年05月19日, 通常, 日本語
  30. Vascular Function and Vascular Structure are Impaired in Patients with Heart Failure with Preserved Ejection Fraction, Shinji Kishimoto, Yukihito Higashi, Nozomu Oda, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yumiko Iwamoto, Tatsuya Maruhashi, Ayumu Nakashima, Takayuki Hidaka, Kensuke Noma, Yasuki Kihara, 88th Scientific Sessions, American Heart Association, 2015年11月08日, 通常, 英語, Orlando, Florida
  31. Paclitaxel-Coated Balloon (PCB)後にslow flowを認め、血管内視鏡を施行した2例, 岸本真治,池永寛樹,栗栖智,渡辺紀晶,下永貴司,檜垣忠直,岩崎年高,石橋堅,土肥由裕,福田幸弘,木原康樹, 第17回中四国血管内視鏡研究会, 2015年12月14日, 通常, 日本語
  32. Vascular Function and Vascular Structure are Impaired in Patients with Heart Failure with Preserved Ejection Fraction, Shinji Kishimoto, Yukihito Higashi, Nozomu Oda, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yumiko Iwamoto, Tatsuya Maruhashi, Ayumu Nakashima, Takayuki Hidaka, Kensuke Noma, Yasuki Kihara, 第80回日本循環器病学会, 2016年03月19日, 通常, 英語
  33. 駆出率の保持された心不全(HFpEF)における血管内皮機能と血管構造, 岸本真治、丸橋達也、梶川正人、岩本明倫、小田望、野間玄督、木原康樹、東幸仁, 第1回日本血管不全学会学術集会, 2016年04月17日, 通常, 日本語
  34. Heart failure with preserved ejection fraction(HFpEF)における血管内皮機能低下と血管構造異常, 岸本真治、丸橋達也、梶川正人、岩本明倫、小田望、野間玄督、木原康樹、東幸仁, 東京, 2016年08月06日, 通常, 日本語
  35. Vascular Function and Rho-associated Kinase Activity in Patients with Idiopathic hyperaldosteronism, Shinji Kishimoto, Takeshi Matsumoto, Shogo matsui, Nozomu Oda, Masato Kajikawa, Yumiko Iwamoto, Tatsuya Maruhashi, Ayumu Nakashima, Takayuki Hidaka, Kensuke Noma, Yasuki Kihara Yukihito Higashi, The Pulse of Asia 2016, 2016年09月24日, 通常, 英語
  36. 2型糖尿病を合併した高血圧症患者におけるアログリプチンの有用性, 岸本真治、丸橋達也、梶川正人 、小田望 、松井翔吾、日高貴之 、野間玄督、木原康樹、東幸仁, 第39回日本高血圧学会, 2016年10月01日, 通常, 日本語
  37. Heart failure with preserved ejection fraction(HFpEF)における血管内皮機能と血管構造, 岸本真治 、東幸仁、松井翔吾 、小田望、梶川正人 、岩本由美子、丸橋達也 、日高貴之、野間玄督、木原康樹, 第20回 日本心不全学術集会, 2016年10月08日, 招待, 日本語
  38. 特発性アルドステロン症における血管内皮機能とRho-associated kinase活性について, 岸本真治、丸橋達也、梶川正人 、小田望 、松井翔吾、野間玄督、木原康樹、東幸仁, 第2回日本血管不全学会学術集会, 2017年04月16日, 通常, 日本語
  39. 血管機能障害・構造異常はHeart failure with preserved ejection fraction(HFpEF) の病因に成り得るか, 岸本真治 、東幸仁、橋本東樹、松井翔吾、梶川正人、岩本由美子、丸橋達也、日高貴之、野間玄督、木原康樹, 第110回 日本循環器病学会中国・四国合同地方会, 2017年06月30日, 通常, 日本語
  40. Patients with Diastolic Ventricular Dysfunction and Ventricular Hypertrophy may occur Heart Failure with Preserved Ejection Fraction through Endothelial Dysfunction, Shinji Kishimoto,Yukihito Higashi,Haruki Hashimoto, Shogo Matsui, Masato Kajikawa, Tatsuya Maruhashi, Farina Mohamad Yusoff, Takayuki Hidaka, Kensuke Noma, Yasuki Kihara, 第82回日本循環器病学会, 2018年03月24日, 通常, 英語
  41. エプレレノンによる特発性アルドステロン症の血管内皮機能への影響, 岸本真治、東幸仁、沖健司、高永甲有司、橋本東樹、松井翔吾、梶川正人、丸橋達也、野間玄督、木原康樹, 第62回広島高血圧・生活習慣病研究会, 2018年11月09日, 通常, 日本語
  42. エプレレノンによる特発性アルドステロン症の血管内皮機能と Rho-associated kinase活性への影響, 岸本真治 、沖健司、 Farina Mohamad Yusoff、高永甲有司、橋本東樹、松井翔吾、梶川正人、丸橋達也、野間玄督、木原康樹、東幸仁, 第15回脳心血管抗加齢研究会, 2018年12月14日, 通常, 日本語, 大阪
  43. Role of Resistin-like Molecule β in Akt/AMPK/Hsp90/eNOS Pathway, Shinji Kishimoto, Yasuki kihara, Yukihito Higashi, the 3rd international symposium of the network-type joint usage/research center for radiation disaster medical science, 2019年01月13日, 通常, 英語
  44. Eplerenone Improves Endothelial Function, Arterial Stiffness and Rho-associated Kinase Activity in Patients with Idiopathic Hyperaldosteronism, 第83回日本循環器学会学術集会, 2019年03月29日, 通常, 英語
  45. Patients with Diastolic Ventricular Hypertrophy and Ventricular Dysfunction may occur Heart Failure with Preserved Ejection Fraction through Endothelial Dysfunction, Shinji Kishimoto 、Yukihito Higashi、Takayuki Yamaji 、Takahiro Harada、Yuji Takaeko、Farina Mohamad Yusoff、Haruki Hashimoto、Masato Kajikawa、Tatsuya Maruhashi、Takayuki Hidaka、Yasuki Kihara, 第23回日本心不全学会学術集会, 2019年10月04日, 通常, 日本語
  46. Eplerenone Improves Vascular Function, Arterial Stiffness and Rho-associated Kinase Activity in Patients with Idiopathic Hyperaldosteronism, Shinji Kishimoto, Yukihito Higashi, Takayuki Yamaji, Takahiro Harada Yuji Takaeko, Farina Mohamad Yusoff, Haruki Hashimoto, Shogo Matsui, Masato Kajikawa, Tatsuya Maruhashi, Kensuke Noma, Yasuki Kihara , American Heart Association Scientific Session 2019, 2019年11月15日, 通常, 英語
  47. Role of Resistin-like Molecule β in Akt/AMPK/Hsp90/eNOS Pathway, Shinji Kishimoto, Takahiro Harada, Takayuki Yamaji, Yiming Han, Yuji Takaeko, Farina Mohamad Yusoff, Haruki Hashimoto, Masato Kajikawa, Tatsuya Maruhashi, Ayumu Nakashima, Yasuki Kihara, Yukihito Higashi, The 4th international symposium of the network-type joint usage/research center for radiation disaster medical science, 2020年02月12日, 通常, 英語

受賞

  1. 2022年11月26日, 日本循環器第121回日本循環器学会中国地方会若手研究者奨励賞(YIA), 野生型トランスサイレチンアミロイドーシス患者の血管内皮機能は維持されている
  2. 2024年02月10日, 第53回日本心脈管作動物質学会 YIA最優秀賞, 高血圧患者におけるコーヒー摂取:血管機能に与える影響
  3. 2025年04月27日, 第9回日本血管不全学会学術集会 優秀演題賞, 第9回日本血管不全学会学術集会, 血管内皮機能評価のための新規測定装置:pFMD
  4. 2021年05月20日, 第21回日本NO学会候補セッション 優秀賞, 日本NO学会理事長/第21回日本NO学会会長
  5. 2018年, 第36回広仁会賞, 広仁会
  6. 2017年06月30日, 第110回日本循環器病学会中国四国合同地方会 若手研究者奨励賞, 日本循環器病学会
  7. 2016年, Pulse of Asia 2016 Travel Grant, Pulse of Asia

外部資金

競争的資金等の採択状況

  1. 科学研究費助成事業(若手研究), 体細胞変異に着目した原発性アルドステロン症の新規治療戦略, 2023年, 2025年
  2. 科学研究費助成事業(若手研究), 動脈硬化に関するレジスチン様分子の役割の解析, 2020年, 2022年

社会活動

学術雑誌論文査読歴

  1. 2024年, Journal of the American Heart Association, その他
  2. 2024年, Hypertension Research, その他
  3. 2024年, Caesiovascular Diabetologhy, その他