湯川 格史Masashi Yukawa

Last Updated :2018/06/01

所属・職名
大学院先端物質科学研究科 分子生命機能科学講座 特任助教
メールアドレス
myukawahiroshima-u.ac.jp
その他連絡先
広島県東広島市鏡山1-3-1先端物質科学総合研究棟・503W
TEL:082-424-7754 FAX:082-424-7754

基本情報

学位

  • 博士(工学) (広島大学)
  • 修士(工学) (広島大学)

研究分野

  • 農学 / 農芸化学 / 応用生物化学

研究キーワード

  • 染色体分配に必須な微小管形成の分子機構解明

所属学会

研究活動

学術論文(★は代表的な論文)

  1. ★, Two spatially distinct Kinesin-14 Pkl1 and Klp2 generate collaborative inward forces against Kinesin-5 Cut7 in S. pombe., JOURNAL OF CELL SCIENCE
  2. ★, A microtubule polymerase cooperates with the Kinesin-6 motor and a microtubule crosslinker to promote bipolar spindle assembly in the absence of Kinesin-5 and Kinesin-14 in fission yeast., MOLECULAR BIOLOGY OF THE CELL, 28巻, 25号, pp.3647-pp.3659
  3. Generation and characterisation of temperature sensitive mutants of genes encoding the fission yeast spindle pole body., PeerJ Preprint (Methods in Molecular Biology, accepted), 5巻, pp.e3377v1
  4. An unconventional interaction between Dis1/TOG and Mal3/EB1 in fission yeast promotes the fidelity of chromosome segregation, JOURNAL OF CELL SCIENCE, 129巻, 24号, pp.4592-pp.4606, 2016, 12, 15
  5. ★, The Msd1-Wdr8-Pkl1 complex anchors microtubule minus ends to fission yeast spindle pole bodies, JOURNAL OF CELL BIOLOGY, 209巻, 4号, pp.549-pp.562, MAY 25 2015
  6. The yeast chromatin remodeler Rsc1-RSC complex is required for transcriptional activation of autophagy-related genes and inhibition of the TORC1 pathway in response to nitrogen starvation, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 464巻, 4号, pp.1248-pp.1253, SEP 4 2015
  7. ★, RSC Chromatin-Remodeling Complex Is Important for Mitochondrial Function in Saccharomyces cerevisiae, PLOS ONE, 10巻, 6号, JUN 18 2015
  8. Fission Yeast Exo1 and Rqh1-Dna2 Redundantly Contribute to Resection of Uncapped Telomeres., PLoS One, 10巻, 10号, pp.e0140456, 2015, Oct, 14
  9. Long G2 accumulates recombination intermediates and disturbs chromosome segregation at dysfunction telomere in Schizosaccharomyces pombe, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 464巻, 1号, pp.140-pp.146, AUG 14 2015
  10. 3,6-Epidioxy-1,10-bisaboladiene inhibits G(1)-specific transcription through Swi4/Swi6 and Mbp1/Swi6 via the Hog1 stress pathway in yeast, FEBS JOURNAL, 281巻, 20号, pp.4612-pp.4621, OCT 2014
  11. Rad51-Dependent Aberrant Chromosome Structures at Telomeres and Ribosomal DNA Activate the Spindle Assembly Checkpoint, MOLECULAR AND CELLULAR BIOLOGY, 34巻, 8号, pp.1389-pp.1397, APR 2014
  12. Fission yeast MOZART1/Mzt1 is an essential gamma-tubulin complex component required for complex recruitment to the microtubule organizing center, but not its assembly, MOLECULAR BIOLOGY OF THE CELL, 24巻, 18号, pp.2894-pp.2906, SEP 15 2013
  13. Fission Yeast RecQ Helicase Rqh1 Is Required for the Maintenance of Circular Chromosomes, MOLECULAR AND CELLULAR BIOLOGY, 33巻, 6号, pp.1175-pp.1187, MAR 2013
  14. A Double Mutant between Fission Yeast Telomerase and RecQ Helicase Is Sensitive to Thiabendazole, an Anti-Microtubule Drug, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 76巻, 2号, pp.264-pp.269, FEB 2012
  15. Fission yeast Pot1 and RecQ helicase are required for efficient chromosome segregation., Mol. Cell. Biol, 31巻, pp.495-pp.506, 20110201
  16. Expression of Mutant RPA in Human Cancer Cells Causes Telomere Shortening, Biosci. Biotechnol. Biochem, 74巻, 2号, pp.382-pp.385, 20100201
  17. A novel method of screening cell-cycle blockers as candidates for anti-tumor reagents by using yeast as a screening tool, Biosci. Biotech. Biochem., 74巻, 2号, pp.411-pp.414, 20100201
  18. ★, The Rpd3/HDAC Complex Is Present at the URS1 cis-Element with Hyperacetylated Histone H3, Bioscience, biotechnology, and biochemistry, 73巻, 2号, pp.378-pp.384
  19. ★, Interplay between chromatin and trans-acting factors on the IME2 promoter upon induction of the gene at the onset of meiosis., Mol. Cell. Biol., 27巻, 4号, pp.1254-pp.1263
  20. Evaluation of image processing programs for accurate measurement of budding and fission yeast morphology., Curr Genet., 49巻, 4号, pp.237-pp.247
  21. High-dimensional and large-scale phenotyping of yeast mutants., Proc Natl Acad Sci USA, 102巻, 52号, pp.19015-pp.19020, 2005, Dec, 27
  22. Fredericamycin A Affects Mitochondrial Inheritance and Morphology in Saccharomyces cerevisiae., Biosci. Biotech. Biochem., 69巻, 11号, pp.2213-pp.2218
  23. Data mining tools for the Saccharomyces cerevisiae morphological database., Nucleic Acids Res., 33(Web Server issue)巻, pp.W753-pp.W757, 2005, Jul, 1
  24. Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases., J Biol Chem., 280巻, 2号, pp.1613-pp.1624
  25. Dynactin is involved in a checkpoint to monitor cell wall synthesis in Saccharomyces cerevisiae., Nat Cell Biol., 6巻, 9号, pp.861-pp.871
  26. SCMD: Saccharomyces cerevisiae Morphological Database., Nucleic Acids Res., 32(Database issue)巻, pp.D319-pp.D322
  27. Functional differences between RSC1 and RSC2, components of growth essential chromatin-remodeling complex of Saccharomyces cerevisiae, during the sporulation process, FEMS Yeast Research, 2巻, 2号, pp.87-pp.91
  28. Borrelidin inhibits a cyclin-dependent kinase (CDK), Cdc28/Cln2, of Saccharomyces cerevisiae, JOURNAL OF ANTIBIOTICS, 54巻, 1号, pp.84-pp.90
  29. ★, Nps1/Sth1p, a component of an essential chromatin-remodeling complex of Saccharomyces cerevisiae is required for the maximal expression of early-meiotic genes, Genes Cells, 4巻, 2号, pp.99-pp.110
  30. 出芽酵母のG2期調節遺伝子NPS1の減数分裂における発現とその調節, 日本分子生物学会年会プログラム・講演要旨集, 19巻, 19960801

著書等出版物

  1. 2007年-7月, 今日の話題 ヒストン脱アセチル化酵素を介した転写タイミングの調節--細胞増殖・発生・分化の過程での遺伝子発現制御の一端が明らかに, 化学と生物 : 日本農芸化学会会誌 : 生命・食糧・環境 / 日本農芸化学会 編, 湯川 格史;井内 智美;土屋 英子
  2. 2006年-8月, ポストゲノムに求められるクロマチン情報の解読(バイオミディア), 生物工学会誌 : seibutsu-kogaku kaishi, 湯川 格史
  3. 1999年-7月, クロマチンリモデリング因子:染色体構造変換に働くタンパク質複合体, 細胞工学, 土屋 英子;細谷 智規;湯川 格史