松尾光一KOICHIMATSUO

Last Updated :2019/10/01

所属・職名
放射光科学研究センター放射光科学研究センター准教授
メールアドレス
pikahiroshima-u.ac.jp

基本情報

学位

  • 博士(理学)(広島大学)
  • 修士(理学)(広島大学)

研究分野

  • 生物学 / 生物科学 / 生物物理学

研究キーワード

  • 放射光, 円二色性, 生体分子

所属学会

  • 日本生物物理学会
  • 日本放射光学会
  • 日本化学会

教育活動

授業担当

  1. 2019年, 学部専門, セメスター(後期), 電磁・量力演習
  2. 2019年, 学部専門, セメスター(前期), 卒業研究A
  3. 2019年, 学部専門, セメスター(後期), 卒業研究B
  4. 2019年, 修士課程・博士課程前期, セメスター(前期), 物理科学特別研究
  5. 2019年, 修士課程・博士課程前期, セメスター(後期), 物理科学特別研究
  6. 2019年, 修士課程・博士課程前期, セメスター(前期), 放射光科学院生実験
  7. 2019年, 修士課程・博士課程前期, セメスター(前期), 放射光科学特論I
  8. 2019年, 修士課程・博士課程前期, セメスター(前期), 放射光物性セミナー
  9. 2019年, 修士課程・博士課程前期, セメスター(後期), 放射光物性セミナー
  10. 2019年, 修士課程・博士課程前期, セメスター(前期), 先端物理科学概論
  11. 2019年, 博士課程・博士課程後期, セメスター(前期), 物理科学特別研究
  12. 2019年, 博士課程・博士課程後期, セメスター(後期), 物理科学特別研究

研究活動

学術論文(★は代表的な論文)

  1. Synchrotron-Radiation Vacuum-Ultraviolet Circular-Dichroism Spectroscopy for Characterizing the Structure of Saccharides, Glycobiophysics, Advances in Experimental Medicine and Biology, 1104巻, pp. 101-117, 20181228
  2. Sample-volume reduction using the Schwarzschild objective for a circular dichroism spectrophotometer and an application to the structural analysis of lysine-36 trimethylated histone H3 protein, Molecules, 2018
  3. Structural analysis of lysine-4 methylated histone H3 proteins using synchrotron radiation circular dichroism spectroscopy, CHIRALITY, 30巻, 5号, pp. 536-540, 201805
  4. Circular dichroism spectroscopic study on structural alterations of histones induced by post-translational modifications in DNA damage responses: lysine-9 methylation of H3, JOURNAL OF RADIATION RESEARCH, 59巻, 2号, pp. 108-115, 201803
  5. 放射光真空紫外円二色性分散計の開発と生体分子構造解析, 日本結晶学会誌, 60巻, pp. 200-208, 201809
  6. Vacuum-ultraviolet circular-dichroism study of oligosaccharides using a synchrotron-radiation spectroscopy, Biomed. Spectrosc. Imaging, 6巻, pp. 111-121, 2017
  7. DNA damage response induces structural alterations in histone H3-H4, JOURNAL OF RADIATION RESEARCH, 58巻, 1号, pp. 59-65, 201701
  8. Conformation of membrane-bound proteins revealed by vacuum-ultraviolet circulardichroism and linear-dichroism spectroscopy, PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 84巻, 3号, pp. 349-359, 201603
  9. Secondary Structure Prediction of Protein Constructs Using Random Incremental Truncation and Vacuum-Ultraviolet CD Spectroscopy, PLOS ONE, 11巻, 6号, 20160607
  10. 放射光真空紫外円二色性による生体分子の構造解析, 分光研究, 65巻, 3号, pp. 172-182, 2016
  11. Vacuum-Ultraviolet Circular Dichroism Spectra of Escherichia coli Dihydrofolate Reductase and Its Mutants: Contributions of Phenylalanine and Tyrosine Side Chains and Exciton Coupling of Two Tryptophan Side Chains, JOURNAL OF PHYSICAL CHEMISTRY B, 119巻, pp. 13002-13008, 2015
  12. Isotope effect on the circular dichroism spectrum of methyl alpha-D-glucopyranoside in aqueous solution, SCIENTIFIC REPORTS, 5巻, 20151214
  13. Niphateolide A: isolation from the marine sponge Niphates olemda and determination of its absolute configuration by an ECD analysis, TETRAHEDRON, 71巻, 38号, pp. 6956-6960, 20150923
  14. Characterization of Intermolecular Structure of beta(2)-Microglobulin Core Fragments in Amyloid Fibrils by Vacuum-Ultraviolet Circular Dichroism Spectroscopy and Circular Dichroism Theory, JOURNAL OF PHYSICAL CHEMISTRY B, 118巻, 11号, pp. 2785-2795, 20140320
  15. An alternative allosteric regulation mechanism of an acidophilic l-lactate dehydrogenase from Enterococcus mundtii 15-1A., An alternative allosteric regulation mechanism of an acidophilic l-lactate dehydrogenase from Enterococcus mundtii 15-1A., 4巻, 2014
  16. An alternative allosteric regulation mechanism of an acidophilic L-lactate dehydrogenase from Enterococcus mundtii 15-1A, FEBS OPEN BIO, 4巻, pp. 834-847, 2014
  17. Overexpression, purification, and characterization of Paenibacillus cell surface-expressed chitinase ChiW with two catalytic domains, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 78巻, 4号, pp. 624-634, 201404
  18. Construction of a Synchrotron-Radiation Vacuum-Ultraviolet Circular-Dichroism Spectrophotometer and Its Application to the Structural Analysis of Biomolecules, BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 86巻, 6号, pp. 675-689, 20130615
  19. Vacuum-ultraviolet circular dichroism of Escherichia coli dihydrofolate reductase: Insight into the contribution of tryptophan residues, CHEMICAL PHYSICS LETTERS, 572巻, pp. 111-114, 20130530
  20. Roussoellols A and B, Tetracyclic Fusicoccanes from Roussoella hysterioides, JOURNAL OF NATURAL PRODUCTS, 76巻, 6号, pp. 1047-1051, 201306
  21. Vacuum-Ultraviolet Electronic Circular Dichroism Study of Methyl alpha-D-Glucopyranoside in Aqueous Solution by Time-Dependent Density Functional Theory, JOURNAL OF PHYSICAL CHEMISTRY A, 116巻, 40号, pp. 9996-10003, 20121011
  22. Secondary-structure analysis of alcohol-denatured proteins by vacuum-ultraviolet circular dichroism spectroscopy, PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 80巻, 1号, pp. 281-293, 201201
  23. Experimental and Theoretical Studies of Vacuum-Ultraviolet Electronic Circular Dichroism of Hydroxy Acids in Aqueous Solution, CHIRALITY, 23巻, 1E号, pp. E52-E58, 2011
  24. Differences in the Molecular Structure of beta(2)-Microglobulin between Two Morphologically Different Amyloid Fibrils, BIOCHEMISTRY, 49巻, 4号, pp. 742-751, 20100202
  25. Membrane-Induced Conformational Change of alpha(1)-Acid Glycoprotein Characterized by Vacuum-Ultraviolet Circular Dichroism Spectroscopy, BIOCHEMISTRY, 48巻, 38号, pp. 9103-9111, 20090929
  26. Vacuum-Ultraviolet Circular Dichroism Analysis of Glycosaminoglycans by Synchrotron-Radiation Spectroscopy, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 73巻, 3号, pp. 557-561, 200903
  27. Comprehensive secondary-structure analysis of disulfide variants of lysozyme by synchrotron-radiation vacuum-ultraviolet circular dichroism, PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 77巻, 1号, pp. 191-201, 200910
  28. Improved sequence-based prediction of protein secondary structures by combining vacuum-ultraviolet circular dichroism spectroscopy with neural network, PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 73巻, 1号, pp. 104-112, 200810
  29. Secondary-structure analysis of denatured proteins by vacuum-ultraviolet circular dichroism spectroscopy, BIOPHYSICAL JOURNAL, 92巻, 11号, pp. 4088-4096, 20070601
  30. Improved estimation of the secondary structures of proteins by vacuum-ultraviolet circular dichroism spectroscopy, JOURNAL OF BIOCHEMISTRY, 138巻, 1号, pp. 79-88, 200507
  31. Vacuum-ultraviolet electronic circular dichroism of L-alanine in aqueous solution investigated by time-dependent density functional theory, JOURNAL OF PHYSICAL CHEMISTRY A, 109巻, 31号, pp. 6928-6933, 20050811
  32. Secondary-structure analysis of proteins by vacuum-ultraviolet circular dichroism spectroscopy, JOURNAL OF BIOCHEMISTRY, 135巻, 3号, pp. 405-411, 200403
  33. Vacuum-ultraviolet circular dichroism study of saccharides by synchrotron radiation spectrophotometry, CARBOHYDRATE RESEARCH, 339巻, 3号, pp. 591-597, 20040225
  34. Optical cell with a temperature-control unit for a vacuum-ultraviolet circular dichroism spectrophotometer, ANALYTICAL SCIENCES, 19巻, 1号, pp. 129-132, 200301
  35. Vacuum-ultraviolet circular dichroism of amino acids as revealed by synchrotron radiation spectrophotometer, CHEMISTRY LETTERS, 8号, pp. 826-827, 20020805
  36. Vacuum-ultraviolet circular dichroism spectrophotometer using synchrotron radiation: Optical system and on-line performance, CHEMISTRY LETTERS, 6号, pp. 522-523, 20010605
  37. Solution structures of methyl aldopyranosides revealed by vacuum-ultraviolet electronic circular-dichroism spectroscopy, Biomedical Spectroscopy and Imaging, 4巻, pp. 269-282, 2015
  38. Effect of sugars on aging of gelatin gels by vacuum-ultraviolet circular dichroism and rheological measurements, Journal of Biorheology, 28巻, pp. 38-44, 2014
  39. Circular-dichroism and synchrotron-radiation circular-dichroism spectroscopy as tools to monitor protein structure in a lipid environment, Methods in Molecular Biology, 974巻, pp. 152-176, 2013
  40. Spectroscopic characterization of inter-molecular interaction of amyloid beta promoted on GM1 micelles, International Journal of Alzheimer's Disease, 2011
  41. 放射光真空紫外円二色性を用いた蛋白質の構造解析法, 蛋白質科学会アーカイブ, 6巻, pp. e064, 2013
  42. 放射光円二色性分光法による蛋白質の精密構造解析と医薬分野への応用, BIO INDUSTRY, 27巻, pp. 63-70, 2010
  43. 放射光円二色性分光による生体分子構造解析のブレークスルー, 化学と工業, 63巻, pp. 652, 2010
  44. 真空紫外円二色性による生体分子の高次元構造解析, 生物と化学, 47巻, pp. 86-87, 2009
  45. 放射光円2色性によるタンパク質の構造解析―構造生物学へのCD分光法の挑戦―, 生物物理, 49巻, pp. 23-24, 2009
  46. 放射光真空紫外円二色性分散計による生体分子の構造解析, 日本放射光学会誌, 17巻, pp. 117-125, 2004

招待講演、口頭・ポスター発表等

  1. Structure Analysis of Oligosaccharides using Synchrotron-Radiation Circular-Dichroism Spectroscopy, Koichi Matsuo, International Workshop on Trends in Advanced Spectroscopy in Materials Science, 2018年10月04日, 通常, 英語, Higashi-Hiroshima
  2. Unique Interaction between Myelin Basic Protein and Phosphatidylinositol 4, 5-Bisphosphate Characterized by Vacuum-Ultraviolet Circular Dichroism Spectroscopy, Munehiro Kumashiro, Yudai Izumi, Koichi Matsuo, International Workshop on Trends in Advanced Spectroscopy in Materials Science, 2018年10月04日, 通常, 英語, Higashi-Hiroshima
  3. Interaction Mechanism between alpha1-Acid Glycoprotein and Membrane Characterized by Vacuum-Ultraviolet Circular-Dichroism Spectroscopy, Koichi Matsuo, Hirofumi Namatame, Masaki Taniguchi, Kunihiko Gekko, 第56回日本生物物理学会, 2018年09月15日, 通常, 英語, 岡山市
  4. Vacuum-Ultraviolet Circular-Dichroism Study of Oligosaccharide Conformations using a Synchrotron-Radiation Spectrophotometer, Koichi Matsuo, 29th International Carbohydrate Symposium - ICS 2018, 2018年07月13日, 通常, 英語, Lisbon, Portugal
  5. Characterization of Biomolecule Structures by Synchrotron-Radiation Vacuum-Ultraviolet Circular-Dichroism Spectroscopy, K. Matsuo, 4th International Symposium on Hybrid Materials and Processing, 2017年11月, 招待, 英語, Pusan, Korea
  6. 真空紫外円二色性による蛋白質の構造解析 と生体分子相互作用研究への応用, 松尾 光一, 第30回日本放射光学会年会・放射光科学合同シンポジウム, 2017年01月07日, 招待, 日本語, 神戸
  7. 放射光円二色性によるタンパク質構造解析法の現状, 松尾 光一, 第4回キラル研究会, 2016年12月10日, 招待, 日本語, 京都
  8. Protein structural analysis by synchrotron-radiation circular-dichroism spectroscopy, Koichi Matsuo, Japan-Korea Student Workshop, 2016年11月24日, 招待, 英語, Hiroshima, Japan
  9. New developments in the structure analysis of biomolecules using synchrotron-radiation vacuum-ultraviolet circular dichroism, Koichi Matsuo, The 13th International School and Symposium on Synchrotron Radiation in Natural Science, 2016年06月16日, 招待, 英語, Ustroń, Poland
  10. 放射光真空紫外円二色性を用いた生体分子構造解析, 松尾 光一, 東北大学・薬学セミナー, 2016年05月25日, 招待, 日本語, 東北大学薬学部
  11. New developments of the protein structural analysis by synchrotron-radiation circular-dichroism spectroscopy, K. Matsuo, International Symposium on EcoTopia Science, 2015年11月28日, 招待, 英語, Nagoya, Japan
  12. Recent progress in structural analysis of biomolecules using HiSOR-SRCD beamline, K. Matsuo, H. Namatame, M. Taniguchi, K. Gekko, 590th WE-Heraeus Seminar Synchrotron Radiation Circular Dichroism Spectroscopy (SRCD), 2015年05月18日, 招待, 英語, Bad Honnef, Germany
  13. Appication of vacuum-ultraviolet circular dichroism spectroscopy to sturutural analysis of biomolecules, K. Matsuo, Seminar in Faculty of Health & Life Sciences De Montfort University, 2015年05月14日, 招待, 英語, Leicester, UK
  14. Vacuum-ultraviolet circular dichroism study of monosaccharides by synchrotron radiation spectroscopy, K. Matsuo, K. Gekko, H. Namatame, M. Taniguchi, Hiroshima International Work Shop on Circular Dichroism Spectroscopy, 2014年03月04日, 招待, 英語, Hiroshima, Japan
  15. Structural analysis of biomolecules using synchrotron-radiation vacuum-ultraviolet circular dichroism spectroscopy, K. Matsuo, H. Namatame, M. Taniguchi, K. Gekko, Annual User’s Meeting and 20th Anniversary of Operation, 2013年09月05日, 招待, 英語, NSRRC, Hinchu, Taiwan
  16. Vacuum-ultraviolet circular dichroism study of saccharides by synchrotron radiation spectroscopy, K. Matsuo, K. Gekko, The 14th International Conference on Chiroptical Spectroscopy, 2013年06月11日, 招待, 英語, Nashville, Tennessee, USA

受賞

  1. 2014年09月04日, 5th European Association For Chemical and Molecular Sciences (EuCheMS), Division of Physical Chemistry, Top Poster Award, 5th EuCheMS Scientific Committee Chair
  2. 2012年03月26日, 日本化学会 進歩賞, 公益社団法人 日本化学会長
  3. 2010年03月, 2009年度Bioscience, Biotechnology, and Biochemistry 論文賞, (社団法人)日本農芸化学会, 各種グリコサミノグリカンとそれらの構成糖の真空紫外円二色性スペクトルを、放射光を用いてはじめて水溶液中で160nmまで測定し、これらの多糖類の溶液構造に及ぼす官能基の寄与ついて重要な知見を与えたことを認定
  4. 2007年07月27日, Carbohydrate Research Most Cited Paper: 2004-2007, Carbohydrate Research