服部 登NOBORU HATTORI

Last Updated :2019/11/01

所属・職名
大学院医系科学研究科(医)(医学)分子内科学教授
メールアドレス
nhattorihiroshima-u.ac.jp

基本情報

学位

  • 博士(医学)(京都大学)

研究分野

  • 医歯薬学 / 内科系臨床医学 / 呼吸器内科学

研究キーワード

  • 肺線維症
  • 胸部悪性腫瘍

教育活動

授業担当

  1. 2019年, 学部専門, 集中, 器官・システム病態制御学I
  2. 2019年, 学部専門, 集中, 医学研究実習
  3. 2019年, 学部専門, 集中, 臨床実習I
  4. 2019年, 学部専門, 集中, 臨床実習I
  5. 2019年, 学部専門, 集中, 臨床実習II
  6. 2019年, 修士課程・博士課程前期, セメスター(後期), 予防医学・健康指導特論Ⅱ
  7. 2019年, 修士課程・博士課程前期, セメスター(後期), 予防医学・健康指導特論Ⅱ
  8. 2019年, 博士課程・博士課程後期, セメスター(前期), 分子内科学特別演習
  9. 2019年, 博士課程・博士課程後期, セメスター(後期), 分子内科学特別演習
  10. 2019年, 博士課程・博士課程後期, セメスター(前期), 分子内科学特別実験
  11. 2019年, 博士課程・博士課程後期, セメスター(後期), 分子内科学特別実験
  12. 2019年, 修士課程・博士課程前期, 3ターム, 予防医学・健康指導特論B
  13. 2019年, 博士課程・博士課程後期, セメスター(前期), 分子内科学特別演習
  14. 2019年, 博士課程・博士課程後期, セメスター(後期), 分子内科学特別演習
  15. 2019年, 博士課程・博士課程後期, セメスター(前期), 分子内科学特別研究
  16. 2019年, 博士課程・博士課程後期, セメスター(後期), 分子内科学特別研究

研究活動

学術論文(★は代表的な論文)

  1. Inhibition of Plasminogen Activator Inhibitor-1 Attenuates Transforming Growth Factor-beta-Dependent Epithelial Mesenchymal Transition and Differentiation of Fibroblasts to Myofibroblasts, PLOS ONE, 11巻, 2号, 20160209
  2. Airway inflammation in Japanese COPD patients compared with smoking and nonsmoking controls, INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 10巻, pp. 185-192, 2015
  3. Effect of increasing respiratory rate on airway resistance and reactance in COPD patients, RESPIROLOGY, 20巻, 1号, pp. 87-94, 201501
  4. Effects of a 6-month nurse-led self-management program on comprehensive pulmonary rehabilitation for patients with COPD receiving home oxygen therapy., Rehabilitation Nursing, 40巻, 1号, pp. 40-51, 2015
  5. Evaluation of prognostic significance of granulocyte-related factors in cancer patients undergoing personalized peptide vaccination, HUMAN VACCINES & IMMUNOTHERAPEUTICS, 11巻, 12号, pp. 2784-2789, 20151202
  6. Histological Quantification of Gene Silencing by Intratracheal Administration of Dry Powdered Small-Interfering RNA/Chitosan Complexes in the Murine Lung, PHARMACEUTICAL RESEARCH, 32巻, 12号, pp. 3877-3885, 201512
  7. Immunological evaluation of peptide vaccination for cancer patients with the HLA-A26 allele, CANCER SCIENCE, 106巻, 10号, pp. 1257-1263, 201510
  8. MT95-4, a fully humanized antibody raised against aminopeptidase N, reduces tumor progression in a mouse model, CANCER SCIENCE, 106巻, 7号, pp. 921-928, 201507
  9. MUC5B promoter polymorphism in Japanese patients with idiopathic pulmonary fibrosis, RESPIROLOGY, 20巻, 3号, pp. 439-444, APR 2015
  10. Baseline KL-6 predicts increased risk for acute exacerbation of idiopathic pulmonary fibrosis, RESPIRATORY MEDICINE, 108巻, 7号, pp. 1031-1039, 201407
  11. Differences in serum SP-D levels between German and Japanese subjects are associated with SFTPD gene polymorphisms, BMC MEDICAL GENETICS, 15巻, 20140108
  12. Characteristics of inspiratory and expiratory reactance in interstitial lung disease, RESPIRATORY MEDICINE, 107巻, 6号, pp. 875-882, 201306
  13. Cross-sectional and prospective study of the association between lung function and prediabetes, BMJ Open, 3巻, 2号, 20130320
  14. Reply to letter to the Editor: rs4072037 Polymorphisms and their role in gastrointestinal carcinogenesis, RESPIRATORY MEDICINE, 107巻, 1号, pp. 159-159, 2013
  15. SK-216, an inhibitor of plasminogen activator inhibitor-1, limits tumor progression and angiogenesis, Molecular Cancer Therapeutics, 12巻, 11号, pp. 2378-2388, 20131101
  16. Cigarette smoking decreases dynamic inspiratory capacity during maximal exercise in patients with type 2 diabetes., Hiroshima J Med Sci, 20120601
  17. Different MUC1 gene polymorphisms in German and Japanese ethnicities affect serum KL-6 levels, RESPIRATORY MEDICINE, 106巻, 12号, pp. 1756-1764, 201212
  18. Interferon(alpha, beta and omega) receptor2 is a prognostic biomarker for lung cancer., Pathobiology, 20120101
  19. Krebs von den Lungen-6 (KL-6) is a prognostic biomarker in patients with surgically resected nonsmall cell lung cancer, INTERNATIONAL JOURNAL OF CANCER, 130巻, 2号, pp. 377-387, 20120115
  20. PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury, JOURNAL OF PATHOLOGY, 228巻, 2号, pp. 170-180, 201210
  21. Utility of KL-6/MUC1 in the clinical management of interstitial lung diseases, Respiratory Investigation, 50巻, 1号, pp. 3-13, 20120301
  22. A pilot study of the multiherb Kampo medicine bakumondoto for cough in patients with chronic obstructive pulmonary disease., Phytomedicine, 18巻, 8-9号, pp. 625-629, 20110601
  23. Aberrant promoter methylation of WIF-1 and SFRP1, 2, 4 genes in mesothelioma, Oncology Reports, 24巻, 2号, pp. 423-431, 20100101
  24. Association of airway inflammation with asthma control level evaluated by the asthma control test, J Asthma, 48巻, 9号, pp. 907-913, 20110901
  25. Change in serum KL-6 level from baseline is useful for predicting life-threatening EGFR-TKIs induced interstitial lung disease, Respir Res, 12巻, pp. 97-107, 20110701
  26. Chronic Hepatitis C Virus Infection is Associated with More Severe Asthma., Allergol Int, 60巻, 3号, pp. 299-304, 20110301
  27. Clinical significance of CD151 gene expression in non-small cell lung cancer, Clinical Cancer Research, 7巻, 12号, pp. 4109-4114, 20011201
  28. Effect of Mustard Gas Exposure on Incidence of Lung Cancer: A Longitudinal Study, AMERICAN JOURNAL OF EPIDEMIOLOGY, 173巻, 6号, pp. 659-666, 2011
  29. Erlotinib efficacy and cerebrospinal fluid concentration in patients with lung adenocarcinoma developing leptomeningeal metastases during gefitinib therapy., Cancer Chemother Pharmacol, 67巻, 6号, pp. 1465-9, 20110101
  30. Intra-airway administration of small interfering RNA targeting plasminogen activator inhibitor-1 attenuates allergic asthma in mice., Am J Physiol Lung Cell Mol Physiol, 301巻, 6号, pp. L908-916, 20110901
  31. KL-6 concentration in pulmonary epithelial lining fluid is a useful prognostic indicator in patients with acute respiratory distress syndrome, RESPIRATORY RESEARCH, 12巻, 2011
  32. Levels of surfactant proteins A and D and KL-6 are elevated in the induced sputum of chronic obstructive pulmonary disease patients: A sequential, Respiration, 82巻, 1号, pp. 10-18, 20110401
  33. Nicergoline improves Dysphagia by upregulating substance p in the elderly, Medicine (Baltimore), 90巻, 4号, pp. 279-283, 20110701
  34. Phase I study docetaxel plus S-1 combination chemotherapy for recurrent non-small cell lung cancer., Oncology Letters, 2巻, pp. 167-170, 20110101
  35. Regression of a primary pulmonary adenocarcinoma after zoledronic acid monotherapy, Hiroshima Journal of Medical Sciences, 60巻, 1号, pp. 7-9, 20110301
  36. Mucins carrying selectin ligands as predictive biomarkers of disseminated intravascular coagulation complication in ARDS., Chest, 139巻, 2号, pp. 296-304, 20100701
  37. Productive cough is an independent risk factor for the development of COPD in former smokers, RESPIROLOGY, 15巻, 2号, pp. 313-318, 201002
  38. Suppression of plasminogen activatior inhibitor-1 by RNA interference attenuates pulmonary fibrosis., Thorax, 65巻, 4号, pp. 334-340, 20100401
  39. The influence of lung function on exercise capacity in patients with type 2 diabetes, Hiroshima Journal of Medical Sciences, 59巻, 1号, pp. 7-13, 20100301
  40. Airflow limitation in smokers is associated with subclinical atherosclerosis, American Journal of Respiratory and Critical Care Medicine, 179巻, 1号, pp. 35-40, 20090101
  41. Genetic ablation of the Bach1 gene reduces hyperoxic lung injury in mice: Role of IL-6, FREE RADICAL BIOLOGY AND MEDICINE, 46巻, 8号, pp. 1119-1126, 2009
  42. IL-12p40 is essential for the down-regulation of airway hyperresponsiveness in a mouse model of bronchial asthma with prolonged antigen exposure, Clinical and Experimental Allergy, 39巻, 2号, pp. 290-298, 20090201
  43. Lymphocyte transformation test is not helpful for the diagnosis of methotrexate-induced pneumonitis in patients with rheumatoid arthritis., Clin Chim Acta, 407巻, 1-2号, pp. 25-29, 20090901
  44. Metastatic breast cancer presenting as air-space consolidation on chest computed tomography., Intern Med, 48巻, 9号, pp. 727-731, 20090301
  45. Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice, J Pharmacol Exp Ther, 328巻, 1号, pp. 55-61, 20090101
  46. Anti-inflammatory effects and clinical efficacy of theophylline and tulobuterol in mild-to-moderate chronic obstructive pulmonary disease, Pulm Pharmacol Ther, 21巻, 6号, pp. 874-878, 20081201
  47. Circulating KL-6/MUC1 as an independent predictor for disseminated intravascular coagulation in acute respiratory distress syndrome, Journal of Internal Medicine, 263巻, 4号, pp. 432-439, 20080401
  48. Suppressor of cytokine signaling1 inhibits pulmonary inflammation and fibrosis, J Allergy Clin Immun, 121巻, 5号, pp. 1269-1276, 20080201
  49. Tiotropium bromide is effective for severe asthma with noneosinophilic phenotype, European Respiratory Journal, 31巻, 6号, pp. 1379-1380, 20080601
  50. Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors, INTERNATIONAL JOURNAL OF CANCER, 122巻, 11号, pp. 2612-2620, 20080601
  51. A case of pulmonary asbestosis presenting with temporal arteritis involving multiple medium-sized vessels., Mod Rheumatol, 18巻, 1号, pp. 100-104, 20071201
  52. A causal relationship between overproduction of collagen and the diminished SOCS1 expression in fibroblasts from idiopathic pulmonary fibrosis., Biochemical and Biophysisal Research Communications, 353巻, 4号, pp. 1004-10, 20070223
  53. Adenoviral transduction of MRP-1/CD9 and KAI1/CD82 inhibits lymph node metastasis in orthotopic lung cancer model., Cancer Research, 67巻, 4号, pp. 1744-1749, 20070215
  54. Circulating KL-6/MUC1 mucin carrying sialyl Lewis(a) oligosaccharide is an independent prognostic factor in patients with lung adenocarcinoma., International journal of cancer, 120巻, 12号, pp. 2643-9, 20070615
  55. Differetial expression of the glycosylated forms of MUC1 during lung development, Eur J Histochem, 51巻, 2号, pp. 95-102, 20070401
  56. Overproduction of collagen and diminished SOCS1 expression are causally linked in fibroblasts from idiopathic pulmonary fibrosis, Biochemical and Biophysical Research Communications, 353巻, 4号, pp. 1004-1010, 20070223
  57. Anti-tumor effect of the anti-KL-6/MUC1 monoclonal antibody through exposure of surface molecules by MUC1 capping, Cancer Science, 97巻, 5号, pp. 420-429, 20060501
  58. Clinical significance of aminopeptidase N in non-small cell lung cancer., Clinical Cancer Res., 12巻, 13号, pp. 3971-3978, 20060601
  59. Effect of CPAP on brachial-ankle pulse wave velocity in patients with OSAHS: An open-labelled study, Respiratory Medicine, 100巻, 12号, pp. 2160-2169, 20061201
  60. KL-6, a human MUC1 mucin, promotes proliferation and survival of lung fibroblasts, Biochemical and Biophysical Research Communications, 338巻, 4号, pp. 1845-1852, 20051230
  61. The Plasminogen Activation System Reduces Fibrosis in the Lung by a Hepatocyte Growth Factor-Dependent Mechanism, American Journal of Pathology, 164巻, 3号, pp. 1091-1098, 20040301
  62. A plasminogen activator inhibitor-1 promoter polymorphism and idiopathic interstitial pneumonia, Molecular Medicine, 9巻, 1-2号, pp. 52-56, 20030101
  63. Clinical significance of transmembrane 4 superfamily in colon cancer, British Journal of Cancer, 89巻, 1号, pp. 158-167, 20030707
  64. Reduction in fibrotic tissue formation in mice genetically deficient in plasminogen activator inhibitor-1, American Journal of Pathology, 163巻, 2号, pp. 445-452, 20030801
  65. Inducible lung-specific urokinase expression reduces fibrosis and mortality after lung injury in mice, American Journal of Physiology - Lung Cellular and Molecular Physiology, 283巻, 5 27-5号, pp. L1023-L1032, 20021101
  66. 薬剤性肺障害を疑うポイントと検査の進め方 (特集 薬剤性肺障害のとらえ方), 月刊薬事 = The pharmaceuticals monthly, 57巻, 2号, pp. 197-200, 201502
  67. 薬剤性浮腫のためクリゾチニブが継続不能となり,アレクチニブへの変更投与により副作用なく部分奏効が得られたEML4-ALK融合遺伝子陽性肺腺癌の1例, 肺癌, 55巻, 4号, pp. 212-217, 2015
  68. これでわかる!最新のバイオマーカー(第5回)間質性肺炎のバイオマーカー, Respiratory medical research, 2巻, 4号, pp. 256-259, 201410
  69. 薬剤性肺障害の診断に必要な検査(1)血液検査,気管支鏡検査,薬剤リンパ球刺激試験(DLST)の意義を中心に (第1土曜特集 内科領域の薬剤性障害 : 肝・肺を中心に) -- (薬剤性肺障害), 医学のあゆみ, 248巻, 1号, pp. 81-85, 20140104
  70. 薬剤性肺障害の検査 (特集 薬剤性肺障害の手引き), アレルギー・免疫, 20巻, 3号, pp. 364-370, 201303
  71. 薬剤性肺障害の診断 (特集 薬剤性肺障害の臨床), 呼吸と循環, 61巻, 4号, pp. 313-318, 201304
  72. 薬剤性肺障害の免疫反応 (特集 免疫学的機序からみた呼吸器疾患), 日本胸部臨床, 72巻, 12号, pp. 1346-1354, 201312
  73. 血清ACE上昇からサルコイドーシスとの鑑別を要した Hodgkin lymphoma の1例, 日本内科学会雑誌, 101巻, 5号, pp. 1401-1403, 20120510
  74. 臨床研究 COPDの咳嗽に対する麦門冬湯の鎮咳効果 (特集 咳と痰 : 漢方ファースト・ステップ), 漢方医学, 36巻, 1号, pp. 26-29, 2012
  75. びまん性肺疾患におけるバイオマーカー (特集 びまん性肺疾患のマイル・ストーン), 綜合臨床, 60巻, 12号, pp. 2416-2418, 201112
  76. 小細胞肺癌の治療後の瘢痕より発生した腺扁平上皮癌の1切除例, 肺癌, 51巻, 3号, pp. 182-187, 2011
  77. 肺性肥大性骨関節症を合併した肺多形癌の1例, 日本呼吸器学会雑誌, 49巻, 10号, pp. 765-768, 20111001
  78. 抗凝固・線溶療法について (特集 間質性肺炎治療法の新展開), 呼吸と循環, 58巻, 4号, pp. 383-387, 201004
  79. ‘09~’10年新型インフルエンザの流行を振り返って, 広島県医師協だより, 476号, pp. 5-10, 20100601
  80. 呼吸器疾患のバイオマーカー (特集 呼吸器疾患診断の進歩--形態と機能の系統的評価), 呼吸と循環, 57巻, 4号, pp. 365-373, 200904
  81. バイオマーカーの有用性と問題点, 呼吸器科, 14巻, 2号, pp. 104-108, 20080801
  82. 間質性肺炎の血清マーカー, 呼吸器科, 13巻, 4号, pp. 297-302, 20080401
  83. 症例からみる肺疾患のCT画像:膠原病に伴う間質性肺炎, medicina, 44巻, 2号, pp. 302-304, 20070210
  84. 新しい検査の意義と使い方 : 4. KL-6とSP-D, 日本内科学会雑誌, 96巻, 10号, pp. 2144-2150, 20071010
  85. 新しい検査の意義と使い方 KL-6とSP-D, 日本内科学会雑誌, 96巻, 10号, pp. 2144-2150, 20070901
  86. 家族性間質性肺炎とSP-Cのかかわりをみる, 分子呼吸器病, 10巻, 2号, pp. 58-60, 20060301
  87. 間質性肺炎・肺線維症:遺伝子多型をめぐる最近の進歩をみる, 分子呼吸器病, 10巻, 1号, pp. 21-26, 20060101
  88. 間質性肺炎の理解 : 肺線維化の機序について, 治療学, 40巻, pp. 1165-1168, 2006
  89. 間質性肺炎の理解:肺線維化の機序について, 治療学, 40巻, 11号, pp. 11-14, 20061101
  90. 肺線維化マーカーの測定意義, 検査と技術, 34巻, 11号, pp. 1170-1171, 20061101
  91. 慢性乾性咳嗽の鑑別診断と治療, Pharma Medica, 24巻, 1号, pp. 110-112, 20060101
  92. 気管支拡張剤無効の慢性咳嗽に対するプランルカストの効果, 医学と薬学, 54巻, pp. 209-212, 2005
  93. 凝固線溶系薬剤 (特集 ARDS/ALIの薬物療法), 呼吸と循環, 52巻, 8号, pp. 793-798, 200408
  94. 2次性肺胞蛋白症及び全身アスペルギルス感染症を認めたALLの1剖検例, 日本胸部疾患学会雑誌, 31巻, 3号, pp. 374-378, 1993
  95. 長期完全寛解持続中に歯肉に再発を生じた赤白血病の1例, 臨床血液, 32巻, 1号, pp. 29-33, 1991
  96. Clinical significance of aminopeptidase N/CD13 expression in human pancreatic carcinoma, Clinical Cancer Research, 9巻, 4号, pp. 1503-1508, 20030401
  97. Clinical significance of aminopeptidase N in non-small cell lung cancer, Clinical Cancer Research, 12巻, 13号, pp. 3971-3978, 20060701
  98. Adenoviral transduction of MRP-1/CD9 and KAI1/CD82 inhibits lymph node metastasis in orthotopic lung cancer model, Cancer Research, 67巻, 4号, pp. 1744-1749, 20070215
  99. Postoperative gluteal skin damage associated with latent development of gluteal muscle damage, JOURNAL OF DERMATOLOGY, 43巻, 5号, pp. 547-552, 201605
  100. Comparative Study of Circulating MMP-7, CCL18, KL-6, SP-A, and SP-D as Disease Markers of Idiopathic Pulmonary Fibrosis, DISEASE MARKERS, 20160317
  101. Long-term pulmonary complications of chemical weapons exposure in former poison gas factory workers, INHALATION TOXICOLOGY, 28巻, 8号, pp. 343-348, 201607
  102. Inhibition of PAI-1 Limits Tumor Angiogenesis Regardless of Angiogenic Stimuli in Malignant Pleural Mesothelioma, CANCER RESEARCH, 76巻, 11号, pp. 3285-3294, 20160601
  103. Sputum Leucine-Rich Alpha-2 Glycoprotein as a Marker of Airway Inflammation in Asthma, PLOS ONE, 11巻, 9号, 20160909
  104. Characterization of sputum biomarkers for asthma-COPD overlap syndrome, INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 11巻, pp. 2457-2465, 20160930
  105. すべての臨床医が知っておくべき薬剤性肺障害.[どうやって見つける?]診断のコツとピットフォール., Mebio, pp. 10-14, December 2014
  106. 間質性肺炎の血清バイオマーカー KL-6., 臨床化学, 44巻, 1号, pp. 24-29, Jan 2015
  107. 薬剤性肺障害を疑うポイントと検査の進め方, 薬事, 2巻, 57号, pp. 197-200, Feb 2015
  108. 高用量の抗真菌薬併用療法が奏効した治療抵抗性侵襲性肺アスペルギルス症の1例, 呼吸, 34巻, 4号, pp. 416-420, April 2015
  109. ペメトレキセドを含む化学療法中の発熱に関する後方視的検討, 広島医学, 68巻, 2号, pp. 97-100, Feb 2015
  110. 2次治療としてカルボプラチンとナブパクリタキセルによる化学療法が奏効した胸腺癌の1例, 日本胸部臨床, 74巻, 8号, pp. 900-908, August 2015
  111. 薬剤性浮腫のためクリゾチニブが継続不能となり、アレクチニブへの変更投与により副作用なく部分奏効が得られたEML4-ALK融合遺伝子陽性肺腺癌の1例, 肺癌, 55巻, 4号, pp. 212-217, August 2015
  112. 結核性胸膜炎治療中に遅発性の胸膜結核腫を発症した1例, 呼吸, 34巻, 10号, pp. 1014-1015, Oct 2015
  113. Efficacy and Safety of Long-Term Sirolimus Therapy for Asian Patients with Lymphangioleiomyomatosis, ANNALS OF THE AMERICAN THORACIC SOCIETY, 13巻, 11号, pp. 1912-1922, 201611
  114. Clinically remitted childhood asthma is associated with airflow obstruction in middle-aged adults, RESPIROLOGY, 22巻, 1号, pp. 86-92, 201701
  115. Carboplatin plus Weekly Paclitaxel Combined with Bevacizumab as First-line Treatment for Non-small Cell Lung Cancer, ANTICANCER RESEARCH, 37巻, 2号, pp. 923-928, 201702
  116. Mustard gas exposure and mortality among retired workers at a poisonous gas factory in Japan: a 57-year follow-up cohort study, OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 74巻, 5号, pp. 321-327, 201705
  117. Immunological evaluation of peptide vaccination for cancer patients with the HLA-A11(+) or-A33(+) allele, CANCER SCIENCE, 108巻, 4号, pp. 598-603, 201704
  118. Suplatast tosilate protects the lung against hyperoxic lung injury by scavenging hydroxyl radicals, FREE RADICAL BIOLOGY AND MEDICINE, 106巻, pp. 1-9, 201705
  119. AGER gene polymorphisms and soluble receptor for advanced glycation end product in patients with idiopathic pulmonary fibrosis, RESPIROLOGY, 22巻, 5号, pp. 965-971, 201707
  120. Westernization of lifestyle affects quantitative and qualitative changes in adiponectin, CARDIOVASCULAR DIABETOLOGY, 16巻, 20170706
  121. Association between aerobic capacity and the improvement in glycemic control after the exercise training in type 2 diabetes, DIABETOLOGY & METABOLIC SYNDROME, 9巻, 20170818
  122. Gene expression profiling of idiopathic interstitial pneumonias (IIPs): identification of potential diagnostic markers and therapeutic targets, BMC MEDICAL GENETICS, 18巻, 20170818
  123. CLINICAL AND MOLECULAR FEATURES OF RAPIDLY PROGRESSIVE CHRONIC HYPERSENSITIVITY PNEUMONITIS, SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES, 34巻, 1号, pp. 48-57, 2017
  124. Chronic Intestinal Pseudo-obstruction and Orthostatic Hypotension Associated with Small Cell Lung Cancer that Improved with Tumor Reduction after Chemoradiotherapy, INTERNAL MEDICINE, 56巻, 19号, pp. 2627-2631, 2017
  125. Risk factors for stomatitis in patients with lymphangioleiomyomatosis during treatment with sirolimus: A multicenter investigator-initiated prospective study, PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 26巻, 10号, pp. 1182-1189, 201710
  126. Feasibility Study of Personalized Peptide Vaccination for Advanced Small Cell Lung Cancer, CLINICAL LUNG CANCER, 18巻, 6号, pp. E385-E394, 201711
  127. AGER rs2070600 polymorphism elevates neutrophil-lymphocyte ratio and mortality in metastatic lung adenocarcinoma, ONCOTARGET, 8巻, 55号, pp. 94382-94392, 20171107
  128. Calneuron 1 Increased Ca2+ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing Adenoma, HYPERTENSION, 71巻, 1号, pp. 125-133, 201801
  129. Additional Octreotide Therapy to Sirolimus Achieved a Decrease in Sirolimus-refractory Chylous Effusion Complicated with Lymphangioleiomyomatosis, INTERNAL MEDICINE, 56巻, 24号, pp. 3327-3331, 2017
  130. Leucine-rich alpha-2 glycoprotein promotes lung fibrosis by modulating TGF-beta signaling in fibroblasts, PHYSIOLOGICAL REPORTS, 5巻, 24号, 201712
  131. The extent of ground-glass attenuation is a risk factor of chemotherapy-related exacerbation of interstitial lung disease in patients with non-small cell lung cancer, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 81巻, 1号, pp. 131-139, 201801
  132. FAM13A polymorphism as a prognostic factor in patients with idiopathic pulmonary fibrosis, RESPIRATORY MEDICINE, 123巻, pp. 105-109, 201702
  133. Aberrant G protein-receptor expression is associated with DNA methylation in aldosterone-producing adenoma, MOLECULAR AND CELLULAR ENDOCRINOLOGY, 461巻, C号, pp. 100-104, FEB 5 2018
  134. A Rare Combination of Dermatomyositis, Interstitial Pneumonia, and Lung Cancer in a Patient Treated with Immunosuppressive Therapy and Chemotherapy, INTERNAL MEDICINE, 57巻, 6号, pp. 849-853, 2018
  135. Putative lung adenocarcinoma with epidermal growth factor receptor mutation presenting as carcinoma of unknown primary site A case report, MEDICINE, 97巻, 7号, 201802
  136. Purkinje Cell Protein 4 Expression Is Associated With DNA Methylation Status in Aldosterone-Producing Adenoma, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 103巻, 3号, pp. 965-971, 201803
  137. Nivolumab-induced severe pancytopenia in a patient with lung adenocarcinoma, LUNG CANCER, 119巻, pp. 21-24, 201805
  138. Acetylcholine receptor antibody-positive myasthenia gravis associated with small-cell lung cancer: A case report, MEDICINE, 97巻, 17号, 201804
  139. Aminopeptidase N/CD13 as a potential therapeutic target in malignant pleural mesothelioma, EUROPEAN RESPIRATORY JOURNAL, 51巻, 5号, 20180501
  140. Japanese guideline for the treatment of idiopathic pulmonary fibrosis, RESPIRATORY INVESTIGATION, 56巻, 4号, pp. 268-291, 201807
  141. Comparative efficacies of daptomycin, vancomycin, and linezolid in experimental enterococcal peritonitis, JOURNAL OF INFECTION AND CHEMOTHERAPY, 23巻, 7号, pp. 498-501, 2017
  142. MUC1 in lung adenocarcinoma: cross-sectional genetic and serological study, BMC CANCER, 17巻, pp. 263, 20170412
  143. 放射線治療によって改善を認めた肺腺癌の下垂体転移を原因とする中枢性尿崩症の1 例, 癌と化学療法, 44巻, 6号, pp. 513-516
  144. ACOSのバイオマーカー, 臨床免疫・アレルギー科, 66巻, pp. 476-481
  145. ACO:喘息とCOPDのオーバーラップ.検査所見・バイオマーカー, Pharma Medica, 35巻, pp. 31-35
  146. 重症難治性気管支喘息に対する気管支サーモプラスティ, 広島医学, 70巻, 6号, pp. 291-292
  147. Bevacizumab with Single-agent Chemotherapy in Previously Treated Non-squamous Non-small-cell Lung Cancer: Phase II Study, IN VIVO, 32巻, 5号, pp. 1155-1160, 2018
  148. Use of proton pump inhibitors is associated with increased mortality due to nosocomial pneumonia in bedridden patients receiving tube feeding, GERIATRICS & GERONTOLOGY INTERNATIONAL, 18巻, 8号, pp. 1215-1218, 201808
  149. Intratracheal Administration of siRNA Dry Powder Targeting Vascular Endothelial Growth Factor Inhibits Lung Tumor Growth in Mice, MOLECULAR THERAPY-NUCLEIC ACIDS, 12巻, pp. 698-706, 20180907
  150. Influenza infection presenting with pulmonary congestion: influenza myocarditis, RESPIROLOGY CASE REPORTS, 6巻, 7号, OCT 2018
  151. Plasminogen activator inhibitor-1 serves an important role in radiation-induced pulmonary fibrosis, EXPERIMENTAL AND THERAPEUTIC MEDICINE, 16巻, 4号, pp. 3070-3076, OCT 2018
  152. Alternate-day administration of S-1 for elderly patients with advanced non-small-cell lung carcinoma: A prospective feasibility study, MOLECULAR AND CLINICAL ONCOLOGY, 9巻, 5号, pp. 539-544, 201811
  153. Effects of Hochuekkito combined with pulmonary rehabilitation in patients with chronic obstructive pulmonary disease, EXPERIMENTAL AND THERAPEUTIC MEDICINE, 16巻, 6号, pp. 5236-5242, 201812
  154. Multicenter phase II study on cisplatin, pemetrexed, and bevacizumab followed by maintenance with pemetrexed and bevacizumab for patients with advanced or recurrent nonsquamous non-small cell lung cancer: MAP study, BMC CANCER, 18巻, 20181210
  155. Measurement of midnight ACTH levels is useful for the evaluation of midnight cortisol levels, STEROIDS, 140巻, pp. 179-184, 201812
  156. Angiotensin 1-7 suppresses angiotensin II mediated aldosterone production via JAK/STAT signaling inhibition, JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 185巻, pp. 137-141, 201901
  157. Small-Cell Lung Cancer Comorbid with Pulmonary Mycobacterium avium Infection: A Case Report, CHEMOTHERAPY, 63巻, 5号, pp. 257-261, 2018
  158. Serial measurements of KL-6 for monitoring activity and recurrence of interstitial pneumonia with anti-aminoacyl-tRNA synthetase antibody A retrospective cohort study, MEDICINE, 97巻, 49号, 201812
  159. Nivolumab therapy for lung cancer with tracheo-parenchymal fistula A case report, MEDICINE, 97巻, 50号, 201812
  160. Pericardial Effusion With Tamponade in Lung Cancer Patients During Treatment With Nivolumab: A Report of Two Cases, FRONTIERS IN ONCOLOGY, 9巻, 20190122
  161. Anti-KL-6/MUC1 monoclonal antibody reverses resistance to trastuzumab-mediated antibody-dependent cell-mediated cytotoxicity by capping MUC1, CANCER LETTERS, 442巻, pp. 31-39, 2019
  162. High preoperative C-reactive protein level is a risk factor for acute exacerbation of interstitial lung disease after non-pulmonary surgery, MEDICINE, 98巻, 5号, 201902
  163. Cerebral embolism during edoxaban administration for venous thromboembolism in a patient with lung adenocarcinoma A case report, MEDICINE, 98巻, 12号, 201903
  164. Inhibition of PAI-1 limits chemotherapy resistance in lung cancer through suppressing myofibroblast characteristics of cancer-associated fibroblasts, JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 23巻, 4号, pp. 2984-2994, 201904
  165. Performance Status Is a Risk Factor for Depression before the Diagnosis of Lung Cancer Patients, INTERNAL MEDICINE, 58巻, 7号, pp. 915-920, 2019
  166. Photochemical generation of the 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) radical from caged nitroxides by near-infrared two-photon irradiation and its cytocidal effect on lung cancer cells, BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 15巻, pp. 863-873, 20190410
  167. Suplatast tosilate reduces radiation-induced lung injury in mice through suppression of oxidative stress, FREE RADICAL BIOLOGY AND MEDICINE, 136巻, pp. 52-59, 20190520
  168. Osimertinib in Elderly Patients with Epidermal Growth Factor Receptor T790M-Positive Non-Small-Cell Lung Cancer Who Progressed During Prior Treatment: A Phase II Trial, ONCOLOGIST, 24巻, 5号, pp. 593-+, 201905
  169. Comparison of anti-aminoacyl-tRNA synthetase antibody-related and idiopathic non-specific interstitial pneumonia, RESPIRATORY MEDICINE, 152巻, pp. 44-50, 201906
  170. A Prospective Cohort Study to Define the Clinical Features and Outcome of Lung Cancers Harboring HER2 Aberration in Japan (HER2-CS STUDY), CHEST, 156巻, 2号, pp. 357-366, 201908
  171. Vertebral Osteomyelitis that Developed During Chemotherapy for Lung Cancer, UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, 28巻, 3号, pp. 199-200, 2018
  172. Small Cell Lung Cancer with Bizarre Radiographic Findings, INTERNAL MEDICINE, 57巻, 23号, pp. 3493-3494, 2018

著書等出版物

  1. 2008年06月, 気管支肺胞洗浄「BAL」の手引き, 京誠堂出版, 2008年, 06, 単行本(学術書), 共編著, 9784771903371, 111
  2. 2007年11月, 呼吸器専門医テキスト, 南江堂, 2007年, 11, 単行本(学術書), 共編著, 9784524238415, 740
  3. 2010年02月, 呼吸器疾患最新治療2010-2012, 南江, 2010年, 02, 単行本(学術書), 共編著, 516
  4. 2010年08月, 特発性肺線維症(IPF), 医薬ジャーナル社, 2010年, 08, 単行本(学術書), 共編著, 280
  5. 2011年05月, 呼吸器研修ノート (研修ノートシリーズ), 診断と治療社, 2011年, 05, 単行本(学術書), 編著, 4787817981, 840
  6. 2009年12月, まんがで読み解く呼吸器症例100 (まんがで読み解くシリーズ), メディカルレビュー社, 2009年, 12, 単行本(学術書), 編著, 4779203732, 283
  7. 2010年02月, 呼吸器疾患最新治療2010-2012, 南江堂, 2010年, 02, 単行本(学術書), 共編著, 524
  8. 2014年04月, 呼吸器外科の術前術後ケア, メディカ出版, 2014年, 4, 単行本(学術書), 共著
  9. 2014年06月, インフォームドコンセントのための図説シリーズ, 医薬ジャーナル社, 2014年, 6, 単行本(学術書), 共著
  10. 特発性間質性肺炎 診断と治療の手引き.改訂第3版., 2016年, 単行本(学術書), 共著
  11. 内科学 11版.(朝倉書店), 2017年, 教科書, 共著
  12. 私の治療 2017-18年度版.(日本医事新報社), 2017年, 単行本(学術書), 共著
  13. 呼吸器疾患診断治療アプローチ 2呼吸器感染症(中山書店), 2017年, 単行本(学術書), 共著