浮穴和義KazuyoshiUkena

Last Updated :2019/10/01

所属・職名
大学院統合生命科学研究科総科・生命・物性・自然(自然探究領域)教授
ホームページ
メールアドレス
ukenahiroshima-u.ac.jp
自己紹介
脳内の新しい調節因子を同定し、生体機能調節(特に食欲などの本能行動)の脳内分子メカニズムを解明しようとしています。行動神経内分泌・代謝学分野での新発見を目指しています。

基本情報

学位

  • 博士(学術)(広島大学)
  • 修士(理学)(広島大学)

研究分野

  • 生物学 / 基礎生物学 / 形態・構造

研究キーワード

  • ニューロステロイド
  • ニューロペプチド

教育活動

授業担当

  1. 2019年, 教養教育, 4ターム, 生物学からみたストレス[旧パッケージ]
  2. 2019年, 教養教育, 3ターム, 生物学実験法・同実験I[1教自,1教人,1生]
  3. 2019年, 教養教育, 4ターム, 生物学実験法・同実験II[1教自,1教人,1生]
  4. 2019年, 学部専門, 2ターム, 生命科学概論
  5. 2019年, 学部専門, 2ターム, 細胞生物学
  6. 2019年, 学部専門, 4ターム, 生命科学実験B
  7. 2019年, 学部専門, 4ターム, 生命科学実験法B
  8. 2019年, 学部専門, 1ターム, 脳機能学
  9. 2019年, 学部専門, セメスター(前期), 生物学基礎実験
  10. 2019年, 学部専門, セメスター(前期), 生物学基礎実験法
  11. 2019年, 修士課程・博士課程前期, セメスター(前期), 総合科学演習
  12. 2019年, 学部専門, 1ターム, Fundamentals of Life Science (ライフサイエンスの世界)
  13. 2019年, 修士課程・博士課程前期, セメスター(後期), 総合科学演習
  14. 2019年, 修士課程・博士課程前期, 3ターム, 進化生命環境学
  15. 2019年, 博士課程・博士課程後期, 年度, 統合生命科学特別研究
  16. 2019年, 修士課程・博士課程前期, 2ターム, 総合科学系演習Ⅰ
  17. 2019年, 修士課程・博士課程前期, 年度, 生命環境総合科学特別研究
  18. 2019年, 修士課程・博士課程前期, 1ターム, 生命環境総合科学特別演習A
  19. 2019年, 修士課程・博士課程前期, 2ターム, 生命環境総合科学特別演習A
  20. 2019年, 修士課程・博士課程前期, 3ターム, 生命環境総合科学特別演習B
  21. 2019年, 修士課程・博士課程前期, 4ターム, 生命環境総合科学特別演習B
  22. 2019年, 修士課程・博士課程前期, 1ターム, 総合科学系概論
  23. 2019年, 修士課程・博士課程前期, 3ターム, 進化生命環境学
  24. 2019年, 博士課程・博士課程後期, 2ターム, 総合科学系演習II
  25. 2019年, 博士課程・博士課程後期, 4ターム, 統合生命総合科学演習
  26. 2019年, 修士課程・博士課程前期, 3ターム, 生命医科学セミナー A
  27. 2019年, 修士課程・博士課程前期, 3ターム, 疾患モデル生物概論
  28. 2019年, 修士課程・博士課程前期, 1ターム, 生命医科学特別演習A
  29. 2019年, 修士課程・博士課程前期, 2ターム, 生命医科学特別演習A
  30. 2019年, 修士課程・博士課程前期, 3ターム, 生命医科学特別演習B
  31. 2019年, 修士課程・博士課程前期, 4ターム, 生命医科学特別演習B
  32. 2019年, 修士課程・博士課程前期, 年度, 生命医科学特別研究
  33. 2019年, 博士課程・博士課程後期, 3ターム, 生命医科学セミナーC

研究活動

学術論文(★は代表的な論文)

  1. Localization and function of neurosecretory protein GM, a novel small secretory protein, in the chicken hypothalamus, SCIENTIFIC REPORTS, 8巻, JAN 15 2018
  2. Effects of chronic intracerebroventricular infusion of neurosecretory protein GL on body mass and food and water intake in chicks, GENERAL AND COMPARATIVE ENDOCRINOLOGY, 256巻, pp. 37-42, JAN 15 2018
  3. Avian and murine neurosecretory protein GL participates in the regulation of feeding and energy metabolism, GENERAL AND COMPARATIVE ENDOCRINOLOGY, 260巻, pp. 164-170, MAY 1 2018
  4. Chronic subcutaneous infusion of neurosecretory protein GM increases body mass gain in chicks, GENERAL AND COMPARATIVE ENDOCRINOLOGY, 265巻, pp. 71-76, SEP 1 2018
  5. Neurosecretory Protein GL, a Hypothalamic Small Secretory Protein, Participates in Energy Homeostasis in Male Mice, ENDOCRINOLOGY, 158巻, 5号, pp. 1120-1129, MAY 2017
  6. Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity, ELIFE, 6巻, AUG 11 2017
  7. The Arg-Phe-amide peptide 26RFa/glutamine RF-amide peptide and its receptor: IUPHAR Review 24, BRITISH JOURNAL OF PHARMACOLOGY, 174巻, 20号, pp. 3573-3607, OCT 2017
  8. Peripheral Injection of Chicken Growth Hormone-Releasing Hormone Inhibits Feeding Behavior in Chicks, JOURNAL OF POULTRY SCIENCE, 53巻, 1号, pp. 29-33, JAN 2016
  9. Identification and localization of gonadotropin-inhibitory hormone (GnIH) orthologs in the hypothalamus of the red-eared slider turtle, Trachemys scripta elegans, GENERAL AND COMPARATIVE ENDOCRINOLOGY, 227巻, pp. 69-76, FEB 1 2016
  10. Synthesis of neurosecretory protein GM composed of 88 amino acid residues by native chemical ligation., Tetrahedron Lett., 57巻, pp. 804-807, 2016
  11. Production and characterization of neurosecretory protein GM using Escherichia coli and Chinese Hamster Ovary cells, FEBS Open Bio, 5巻, pp. 844-851
  12. Effects of neurotensin and LANT-6 on food intake in chicks, Am. J. Life Sci., 3巻, pp. 17-23
  13. A unique mechanism of successful fertilization in a domestic bird, SCIENTIFIC REPORTS, 5巻, JAN 9 2015
  14. Central administration of chicken growth hormone-releasing hormone decreases food intake in chicks, PHYSIOLOGY & BEHAVIOR, 139巻, pp. 195-201, FEB 2015
  15. Microwave-assisted solid-phase peptide synthesis of neurosecretory protein GL composed of 80 amino acid residues, JOURNAL OF PEPTIDE SCIENCE, 21巻, 6号, pp. 454-460, JUN 2015
  16. 26Rfa/GPR103, JOURNAL OF MOLECULAR ENDOCRINOLOGY, 52巻, 3号, pp. T119-T131, JUN 2014
  17. Characterization of an avian histidine decarboxylase and localization of histaminergic neurons in the chicken brain, NEUROSCIENCE LETTERS, 578巻, pp. 106-110, AUG 22 2014
  18. Identification of a cDNA encoding a novel small secretory protein, neurosecretory protein GL, in the chicken hypothalamic infundibulum, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 446巻, 1号, pp. 298-303, MAR 28 2014
  19. Identification of Neurotensin and LANT-6 and Localization of mRNA Encoding Their Precursor in the Chicken Brain, ZOOLOGICAL SCIENCE, 31巻, 6号, pp. 353-359, JUN 2014
  20. Identification, localization and function of a novel neuropeptide, 26RFa, and its cognate receptor, GPR103, in the avian hypothalamus, GENERAL AND COMPARATIVE ENDOCRINOLOGY, 190巻, pp. 42-46, SEP 1 2013
  21. ニワトリにおいて視床下部漏斗部に特異的発現を示す新規遺伝子の同定, 日本家禽学会誌, 50巻, pp. J10-J15
  22. Identification, Expression, and Physiological Functions of Siberian Hamster Gonadotropin-Inhibitory Hormone, ENDOCRINOLOGY, 153巻, 1号, pp. 373-385, JAN 2012
  23. Characterization of novel antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae by shotgun cDNA cloning, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 412巻, 4号, pp. 673-677, SEP 9 2011
  24. Identification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae, PEPTIDES, 32巻, 4号, pp. 670-676, APR 2011
  25. Identification and structure-activity relationship of an antimicrobial peptide of the palustrin-2 family isolated from the skin of the endangered frog Odorrana ishikawae, PEPTIDES, 32巻, 10号, pp. 2052-2057, OCT 2011
  26. Identification, Localisation and Functional Implication of 26RFa Orthologue Peptide in the Brain of Zebra Finch (Taeniopygia guttata), JOURNAL OF NEUROENDOCRINOLOGY, 23巻, 9号, pp. 791-803, SEP 2011
  27. Molecular evolution and functional characterization of the orexigenic peptide 26RFa and its receptor in vertebrates, CELL AND TISSUE RESEARCH, 343巻, 3号, pp. 475-481, MAR 2011
  28. Synchronised Expressions of LPXRFamide Peptide and its Receptor Genes: Seasonal, Diurnal and Circadian Changes During Spawning Period in Grass Puffer, JOURNAL OF NEUROENDOCRINOLOGY, 23巻, 1号, pp. 39-51, JAN 2011
  29. Identification, Localization, and Function of a Novel Avian Hypothalamic Neuropeptide, 26RFa, and Its Cognate Receptor, G Protein-Coupled Receptor-103, ENDOCRINOLOGY, 151巻, 5号, pp. 2255-2264, MAY 2010
  30. A New Key Neurohormone Controlling Reproduction, Gonadotrophin-Inhibitory Hormone in Birds: Discovery, Progress and Prospects, JOURNAL OF NEUROENDOCRINOLOGY, 21巻, 4号, pp. 271-275, APR 2009
  31. Expression, localization and possible actions of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell of the cerebellum: A new insight into the biosynthesis, metabolism and multiple actions of progesterone as a neurosteroid, CEREBELLUM, 7巻, 1号, pp. 18-25, MAR 2008
  32. The orexigenic effect of GnIH is mediated by central opioid receptors in chicks, COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, 150巻, 1号, pp. 21-25, MAY 2008
  33. Unique Form and Osmoregulatory Function of a Neurohypophysial Hormone in a Urochordate, Endocrinology, 149巻, 10号, pp. 5254-5261, 20081001
  34. Discovery of gonadotropin-inhibitory hormone in a domesticated bird, its mode of action and functional significance, JOURNAL OF ORNITHOLOGY, 148巻, pp. S515-S520, DEC 2007
  35. Discovery of gonadotropin-inhibitory hormone in a domesticated bird, its mode of action and functional significance., Journal of Ornithology, 148号, pp. 515-520, 20070908
  36. Expression, localization and possible actions of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell of the cerebellum: A new insight into the biosynthesis, metabolism and multiple actions ofprogesterone as a neurosteroid., Cerebellum, pp. 1-8, 20070302
  37. Gonadotropin-inhibitory hormone in seasonally-breeding songbirds: neuroanatomy and functional biology, Journal of Ornithology, 148号, pp. 521-526, 20070911
  38. Gonadotropin-inhibitory hormone in seasonally-breeding songbirds: neuroanatomy and functional biology, JOURNAL OF ORNITHOLOGY, 148巻, pp. S521-S526, DEC 2007
  39. The general and comparative biology of gonadotropin-inhibitory hormone (GnIH)., General and Comparative Endocrinology, 153号, pp. 365-370, 20070801
  40. 生殖神経内分泌学における新しい視床下部調節因子, 日本生殖内分泌学会雑誌, 12号, pp. 27-29, 20070930
  41. Evolutionary origin and divergence of PQRFamide peptides and LPXRFamide peptides in the RFamide peptide family., FEBS J., 273巻, pp. 1731-1743, 20060401
  42. Gonadotropin-inhibitory hormone inhibits gonadal development and maintenance by decreasing gonadotropin synthesis and release in male quail., Endocrinology, 147巻, pp. 1187-1194, 20060401
  43. Hypothalamic LPXRF-amide peptides in vertebrates: Identification, localization and hypophysiotropic activity (review)., Peptides, 27巻, pp. 1121-1129, 20060401
  44. Identification and characterization of a gonadotropin-inhibitory system in the brains of mammals., Proc. Natl. Acad. Sci. USA, 103巻, pp. 2410-2415, 20060401
  45. Interactions of gonadotropin-releasing hormone (GnRH) and gonadotropin-inhibitory hormone (GnIH) in birds and mammals., J. Exp. Zool., 305巻, pp. 807-814, 20060401
  46. Mode of action and functional significance of avian gonadotropin-inhibitory hormone (GnIH): a review., J. Exp. Zool., 305巻, pp. 801-806, 20060401
  47. Neural interaction of gonadotropin-regulating hormone immunoreactive neurons and the suprachiasmatic nucleus with the paraventricular organ in the Japanese grass lizard (Takydromus tachydromoides)., Zool. Sci., 23巻, pp. 277-287, 20060401
  48. Neurosteroid biosynthesis in the quail brain: a review., J. Exp. Zool., 305巻, pp. 733-742, 20060401
  49. Novel fish hypothalamic neuropeptides stimulate the release of gonadotrophins and growth hormone from the pituitary of sockeye salmon, JOURNAL OF ENDOCRINOLOGY, 188巻, 3号, pp. 417-423, MAR 2006
  50. Structures and diverse functions of frog growth hormone-releasing peptide (fGRP) and its related peptides (fGRP-RPs): A review, JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-COMPARATIVE EXPERIMENTAL BIOLOGY, 305A巻, 9号, pp. 815-821, SEP 1 2006
  51. A new member of the hypothalamic RF-amide peptide family, LPXRF-amide peptides: Structure, localization, and function, MASS SPECTROMETRY REVIEWS, 24巻, 4号, pp. 469-486, JUL-AUG 2005
  52. A novel G protein-coupled receptor for gonadotropin-inhibitory hormone in the Japanese quail (Coturnix japonica): identification, expression and binding activity, JOURNAL OF ENDOCRINOLOGY, 184巻, 1号, pp. 257-266, JAN 2005
  53. Gonadotropin-inhibiting hormone stimulates feeding behavior in chicks., Brain Res., 1050巻, pp. 94-100, 20050401
  54. Melatonin induces the expression of gonadotropin-inhibitory hormone in the avian brain., Proc. Natl. Acad. Sci. USA, 102巻, pp. 3052-3057, 20050401
  55. 総説:発達期の小脳プルキンエ細胞における25-Dxの発現-プルキンエ細胞が合成するプロゲステロンの作用機構-, 生体の科学, 56巻, pp. 296-302, 20050401
  56. 7 alpha-Hydroxypregnenolone acts as a neuronal activator to stimulate locomotor activity of breeding newts by means of the dopaminergic system, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 101巻, 49号, pp. 17282-17287, DEC 7 2004
  57. Dendritic growth in response to environmental estrogens in the developing Purkinje cell in rats., Neurosci. Lett., 364巻, pp. 114-118, 20040401
  58. Expression and distribution of octopus gonadotropin-releasing hormone in the central nervous system and peripheral organs of the octopus (Octopus vulgaris) by in situ hybridization and immunohistochemistry., J. Comp. Neurol., 477巻, pp. 310-323, 20040401
  59. Expression and localization of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell., Neuroscience, 126巻, pp. 325-334, 20040401
  60. Gonadotrophin inhibitory hormone depresses gonadotrophin alpha and follicle-stimulating hormone beta Subunit expression in the pituitary of the domestic chicken., J. Neuroendocrinol., 16巻, pp. 999-1006, 20040401
  61. Gonadotropin-inhibitory hormone in Gambelユs white-crowned sparrow (Zonotrichia leucophrys gambelli): cDNA identification, transcript localization and functional effects in laboratory and field experiments., J. Endocrinol., 182巻, pp. 33-42, 20040401
  62. Identification of 3b,5b-tetrahydroprogesterone, a progesterone metabolite, and its stimulatory action on preoptic neurons in the avian brain., Brain Res., 1007巻, pp. 160-166, 20040401
  63. Organizing actions of neurosteroids in the Purkinje neuron, NEUROSCIENCE RESEARCH, 49巻, 3号, pp. 273-279, JUL 2004
  64. Photoperiodic response of serotonin- and galanin-immunoreactive neurons of the paraventricular organ and infundibular nucleus in Japanese quail, Coturnix cotumix japonica, ZOOLOGICAL SCIENCE, 21巻, 5号, pp. 575-582, MAY 2004
  65. A novel aspect of the cerebellum: biosynthesis of neurosteroids in the Purkinje cell, CEREBELLUM, 2巻, 3号, pp. 215-222, 2003
  66. Biosynthesis and action of neurosteroids in the cerebellar Purkinje neuron., J. Steroid Biochem. Mol. Biol., 85巻, pp. 311-321, 20030401
  67. Biosynthesis and biological actions of neurosteroids in the avian brain., Avian Poult. Biol. Rev., 14巻, pp. 63-78, 20030401
  68. Dendritic growth and spine formation in response to estrogen in the developing Purkinje cell., Endocrinology, 144巻, pp. 4466-4477, 20030401
  69. Developmental changes in gonadotropin-inhibitory hormone in the quail hypothalamo-hypophysial system., J. Endocrinology, 178巻, pp. 311-318, 20030401
  70. Distribution of a novel avian gonadotropin-inhibitory hormone in the quail brain., Cell Tissue Res., 312巻, pp. 73-79, 20030401
  71. Gonadotropin-inhibitory peptide in song sparrows (Melospiza melodia) in different reproductive conditions, and in house sparrows (Passer domesticus) relative to chicken-Gonadotropin-releasing hormone., J. Neuroendocrinol., 15巻, pp. 794-802, 20030401
  72. Neonatal expression of progesterone receptor isoforms in the cerebellar Purkinje cell in rats., Neurosci. Lett., 343巻, pp. 163-166, 20030401
  73. Review: Biosynthesis and biological actions of neurosteroids in the avian brain., Avian Poultry Biol Reviews, 14巻, pp. 63-78, 20030401
  74. Review:A novel aspect of the cerebellum: Biosynthesis of neurosteroids in the Purkinje cell., Cerebellum, 2巻, pp. 215-222., 20030401
  75. Seasonal changes in neurosteroid concentrations in the amphibian brain and environmental factors regulating their changes, BRAIN RESEARCH, 959巻, 2号, pp. 214-225, JAN 10 2003
  76. 総説:ニューロステロイドのシナプス形成誘導作用, 生体の科学, 54巻, pp. 130-137, 20030401
  77. 総説:ニューロンが合成するニュー ロステロイドのノンゲノミック作用とゲノミック作用, 日本生殖内分泌学会雑誌, 8巻, pp. 19-26, 20030401
  78. A novel amphibian hypothalamic neuropeptide: Isolation, localization, and biological activity, ENDOCRINOLOGY, 143巻, 2号, pp. 411-419, FEB 2002
  79. A novel rat hypothalamic RFamide-related peptide identified by immunoaffinity chromatography and mass spectrometry, FEBS LETTERS, 512巻, 1-3号, pp. 255-258, FEB 13 2002
  80. Androgen biosynthesis in the quail brain, BRAIN RESEARCH, 948巻, 1-2号, pp. 180-185, SEP 6 2002
  81. Dendritic spine formation in response to progesterone synthesized de novo in the developing Purkinje cell in rats., Neurosci. Lett., 322巻, pp. 111-115, 20020401
  82. Expression and localization of cytochrome P45011β,aldo mRNA in the frog brain., Brain Res., 950巻, pp. 288-296, 20020401
  83. Identification of a cDNA encoding a novel amphibian growth hormone-releasing peptide and localization of its transcript., J. Endocrinol., 174巻, pp. 395-402, 20020401
  84. Isolation and characterization of a GnRH-like peptide from Octopus vulgaris., Biochem. Biophys. Res. Commun., 291巻, pp. 1187-1193, 20020401
  85. Novel fish hypothalamic neuropeptide - Cloning of a cDNA encoding the precursor polypeptide and identification and localization of the mature peptide, EUROPEAN JOURNAL OF BIOCHEMISTRY, 269巻, 24号, pp. 6000-6008, DEC 2002
  86. A novel hypothalamic neuropeptide: Gonadotropin-inhibitory hormone., Internat. J. Mol. Med., 8巻, pp. 400-405, 20010401
  87. Activity and localization of 3 beta-hydroxysteroid dehydrogenase/Delta(5)-Delta(4)-isomerase in the zebrafish central nervous system, JOURNAL OF COMPARATIVE NEUROLOGY, 439巻, 3号, pp. 291-305, OCT 22 2001
  88. Characterization of a cDNA encoding a novel avian hypothalamic neuropeptide exerting an inhibitory effect on gonadotropin release., Biochem. J., 354巻, pp. 379-385, 20010401
  89. Developmental changes in galanin in lumbosacral sympathetic ganglionic neurons innervating the avian uterine oviduct and galanin induction by sex steroids., J. Endocrinol., 170巻, pp. 357-368, 20010401
  90. Developmental changes in progesterone biosynthesis and metabolism in the quail brain., Brain Res., 898巻, pp. 190-194, 20010401
  91. Distribution of novel RFamide-related peptide-like immunoreactivity in the mouse central nervous system., Neurosci. Lett., 300巻, pp. 153-156, 20010401
  92. Effects of progesterone synthesized de novo in the developing Purkinje cell on its dendritic growth and synaptogenesis., J. Neurosci., 21巻, pp. 6221-6232, 20010401
  93. Expression and localization of cytochrome P450 17α-hydroxylase/c17,20-lyase in the avian brain., Brain Res., 899巻, pp. 112-122, 20010401
  94. A novel avian hypothalamic peptide inhibiting gonadotropin release, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 275巻, 2号, pp. 661-667, AUG 28 2000
  95. Existence of galanin in lumbosacral sympathetic ganglionic neurons that project to the quail uterine oviduct., Endocrinology, 141巻, pp. 4402-4412, 20000401
  96. Neurosteroid biosynthesis in the avian brain., 4th International Symposium on Recent Trends in Life Sciences, pp. 25, 20000401
  97. Neurosteroidogenesis in the avian brain., VII International Symposium on Avian Endocrinology, 20000401
  98. Novel brain function: biosynthesis and actions of neurosteroids in neurons, NEUROSCIENCE RESEARCH, 36巻, 4号, pp. 261-273, APR 2000
  99. Production of progesterone and expression of progesterone receptor in the brain of the non-breeding and brooding ring dove., VII International Symposium on Avian Endocrinology, 20000401
  100. Review:Novel brain function : biosynthesis and actions of neurosteroids in neurons, Neurosci. Res., 36巻, pp. 261-273, 20000401
  101. ニューロステロイドはGABAレセプターに作用する, 化学と生物, 38巻, pp. 179-180, 20000401
  102. 新しく見出された鳥類産卵の神経制御機構:微小脳が合成する産卵誘起ペプチドとその作用機構, 日本比較内分泌学会ニュース, 96巻, pp. 17-22, 20000401
  103. 総説 : 神経ステロイドによるシナプス可塑性調節 特集:脳のシナプス, Brain Medical, 12巻, pp. 298-306, 20000401
  104. Comparison of precursor structures of the GGNG peptides derived from the earthworm Eisenia foetida and the leech Hirudo nipponia., Biosci. Biotechnol. Biochem., 63巻, pp. 443-445, 19990401
  105. Expression and activity of 3b-hydroxysteroid dehydrogenase/D5-D4-isomerase in the rat Purkinje neuron during neonatal life., Endocrinology, 140巻, pp. 805-813, 19990401
  106. Expression and activity of 3β-hyodroxysteroid dehydrogenase/D5-D4-isomerase in different regions of the avian brain., Brain Research, 818巻, pp. 536-542, 19990401
  107. Localization of the leech excitatory peptide, a member of the GGNG peptides, in the central nervous system of a leech (Whitmania pigra) by immunohistochemistry and in situ hybridization, Cell Tissue Res., 297巻, pp. 155-162, 19990401
  108. Neurosteroids in the cerebellar purkinje neuron and their actions., Int. J. Mol. Med., 4巻, pp. 49-56, 19990401
  109. Possible functions of oxytocin/vasopressin-superfamily peptides in annelids with special reference to reproduction and osmoregulation, Journal of Experimental Zoology, 284巻, pp. 401-406, 19990401
  110. Pregnenolone, pregnenolone sulfate, and cytochrome P450 side-chain cleavage enzyme in the amphibian brain and their seasonal changes., Endocrinology, 140巻, pp. 1936-1944, 19990401
  111. Review: Production and function of neurosteroids in the cerebellar Purkinje neuron., International Journal of Molecular Medicine, 4巻, pp. 49-56, 19990401
  112. Review:Neurosteroids in vertebrate brains., Comparative Biochemistry and Physiology Part C, 124巻, pp. 121-129, 19990401
  113. 総説:鳥類の微小脳の繁殖戦略:産卵誘起ペプチドとその作用機構, 比較生理生化学(比較生理生化学会編), 16巻, pp. 191-199, 19990401
  114. Age-and region-specific expressions of the messenger RNAs encoding for steroidogenic enzymes P450scc, P450c17 and 3β-HSD in the postnatal rat brain., Brain Research, 801巻, pp. 233-238, 19980401
  115. Cytochrome P450 side-chain cleavage enzyme in the cerebellar Purkinje neuron and its neonatal change in rats., Endocrinology, 139巻, pp. 137-147, 19980401
  116. Developmental changes in galanin receptors in the quail oviduct and the effect of ovarian sex steroids on galanin receptor induction., Endocrinology, 139巻, pp. 4230-4236, 19980401
  117. Immunohistochemical localization of annetocin, an earthworm oxytocin-related peptide, and identification and ultrastructural characteristics of the annetocin-secretory cells in the oligochaete earthworm Eisenia foetida., Zoological Science, 15巻, pp. 381-388, 19980401
  118. Biosynthesis and function of neurosteroids in the rat cerebellar Purkinje neuron., Evolutionary Aspects of Chemical Messengers and Their Receptors, pp. 48, 19970401
  119. Characterization of binding of the annelidan myoactive peptides, GGNG peptides, to tissues of the earthworm, Eisenia foetida, Journal of Experimental Zoology, 279巻, pp. 562-570, 19970401
  120. Immunochemical demostration of Eisenia tetradecapeptide, a bioactive peptide isolated from the gut of the earthworm Eisenia foetida, in tissues of the earthworm., Cell Tissue Res., 288巻, pp. 567-573, 19970401
  121. The leech excitatory peptide, a member of the GGNG peptide family : isolation and comparison with the earthworm GGNG peptides., FEBS Lett, 410巻, pp. 437-442, 19970401
  122. An excitatory tetradecapeptide isolated from the gut of the earthworm, Eisenia foetida, Proc. 3rd Congr. Asia-Oceania Soc. Comp. Endocrinol., pp. 236-237, 19960401
  123. Annetocin, an annelid oxytocin-related peptide, induces egg-laying behavior in the earthworm, Eisenia foetida., J. Exp. Zool., 276巻, pp. 151-156, 19960401
  124. Annetocin, an annelid oxytocin-related peptide, induces egg-laying behavior of the earthworm, Eisenia foetida, Proc. 3rd Congr. Asia-Oceania Soc. Comp. Endocrinol., pp. 234-235, 19960401
  125. Bioactivity and cDNA cloning of GGNG peptides isolated from the earthworms and the leech, Proc. 3rd Congr. Asia-Oceania Soc. Comp. Endocrinol., pp. 209-210, 19960401
  126. Gene structures of the GGNG-peptides derived from Annelida and the gene products, Peptide Chem, 1995巻, pp. 321-324, 19960401
  127. Inhibitory pentapeptides isolated from the gut of the earthworm, Eisenia foetida., Comp. Biochem. Physiol. A., 114巻, pp. 245-249, 19960401
  128. A novel gut tetradecapeptide isolated from the earthworm, Eisenia foetida., Peptides, 16巻, pp. 995-999, 19950401
  129. Bioactive peptides of annelids are closely related to those of molluscs, Acta Biologica Hungarica, 46巻, 2-4号, pp. 453-456, 19950401
  130. Effects of annetocin, an oxytocin-related peptide isolated from the earthworm Eisenia foetida, and some putative neurotransmitters on gut motility of the earthworm., J. Exp. Zool., 272巻, pp. 184-193, 19950401
  131. Neurosteroid biosynthesis in vertebrate brains., Comparative Biochem. Physiol. Part C, 124巻, pp. 121-129, 19950601
  132. The GGNG peptides : novel myoactive peptides isolated from the gut and the whole body of the earthworms., Biochem. Biophys. Res. Commun., 216巻, pp. 1072-1078, 19950401
  133. Annetocin : an oxytocin-related peptide isolated from the earthworm, Eisenia foetida., Biochem. Biophys. Res. Commun., 198巻, pp. 393-399, 19940401

著書等出版物

  1. 2015年, Handbook of Hormones. Comparative Endocrinology for Basic and Clinical Research, Pyroglutamylated RFamide Peptide, Elsevier, 2015年, 単行本(学術書), 共著, Ukena K, Tsutsui K, 16-17
  2. 2007年10月, Study on processing mechanisms of novel identified neuropeptides. , ノバルティス科学振興財団 No.19:56-57 Annual Report 2007, 2007年, 10, 調査報告書, 単著, 浮穴 和義
  3. 2007年10月, 生体リズム障害に関わる新規神経ペプチドの機能解析 , 財団法人 テルモ科学技術振興財団 2006年度一般研究助成 研究実施報告書集 51-53, 2007年, 10, 調査報告書, 単著, 浮穴 和義
  4. 2007年07月, 脳ホルモンの新領域 , 培風館, 2007年, 07, 単行本(学術書), 共著, 筒井 和義 浮穴 和義 南方 博之
  5. 2007年11月, 微量神経ペプチドの同定のための質量分析法の開発 , 倉田奨励金研究報告 第37集, 2007年, 11, 調査報告書, 単著, 浮穴 和義
  6. 2007年03月, 未知の脳ホルモンの発見を目指して , 財団法人 医薬資源研究振興会 財団報 No.23:38, 2007年, 03, 調査報告書, 単著, 浮穴 和義
  7. 2004年, A novel amphibian neurosteroid stimulating locomotor activity. , Trends in Comparative Endocrinology= AOSCE, 2004年, 単行本(学術書), 共著, 浮穴 和義
  8. 2004年, Classical and novel neurosteroids in vertebrate brains. , Trends in Comparative Endocrinology= AOSCE, 2004年, 単行本(学術書), 共著, tsutsui k matsunaga m miyabara h ukena k 浮穴 和義
  9. 2004年, Comparative aspects of novel hypothalamic LPXRF-amide peptides in the vertebrate brain: Structure, localization and function. , Trends in Comparative Endocrinology= AOSCE, 2004年, 単行本(学術書), 共著, 浮穴 和義
  10. 2004年, Effects of RF-amide peptides on the release of TSH from the bullfrog pituitary. , Trends in Comparative Endocrinology= AOSCE, 2004年, 単行本(学術書), 共著, 浮穴 和義
  11. 2004年, Identification and localization of a novel lamprey hypothalamic neuropeptide of the RF-amide peptide family. , Trends in Comparative Endocrinology= AOSCE, 2004年, 単行本(学術書), 共著, 浮穴 和義
  12. 2004年, Novel avian neurosteroid: Identification of 7alpha-hydroxypregnenolone in the quail brain. , Trends in Comparative Endocrinology= AOSCE, 2004年, 単行本(学術書), 共著, 浮穴 和義
  13. 2004年, Synapse formation in response to estrogen synthesized de novo in the developing Purkinje cell. , Trends in Comparative Endocrinology= AOSCE, 2004年, 単行本(学術書), 共著, 浮穴 和義
  14. 2003年, Biosynthesis and action of neurosteroids in the cerebellar Purkinje neuron. , Hormonal Steroids and Hormones and Cancer, 2003年, 単行本(学術書), 共編著, 浮穴 和義 坂本 博和 筒井 和義
  15. 2002年, Novel cerebellar function: neurosteroids in the Purkinje neuron and their genomic and nongenomic actions. , Neuroplasticity= development= and steroid hormone action= CRC press, 2002年, 単行本(学術書), 共著, 浮穴 和義
  16. 2001年, A novel avian hypothalamic peptide. , Recent Advances in Comparative Endocrinology= Academia Sinica, 2001年, 単行本(学術書), 共著, 浮穴 和義
  17. 2001年, A novel hypothalamic peptide inhibiting gonadotropin release. , Perspective in Comparative Endocrinology: Unity and Diversity= Medimond Inc., 2001年, 単行本(学術書), 共著, 浮穴 和義
  18. 2001年, Isolation and characterization of a GnRH-like peptide from Octopus Vulgaris. , Perspective in Comparative Endocrinology: Unity and Diversity= Medimond Inc., 2001年, 単行本(学術書), 共著, 浮穴 和義
  19. 2001年, Sympathetic ganglionic galanin neurons evoke avian oviposition by innervating the uterine oviduct: a novel neuronal mechanism of avian oviposition. , Perspective in Comparative Endocrinology: Unity and Diversity= Medimond Inc., 2001年, 単行本(学術書), 共著, 浮穴 和義
  20. 2000年, Neuronal neurosteroidogenesis in the cerebellum. , Molecular Steroidogenesis= Universal Academy Press, 2000年, 単行本(学術書), 共著, 浮穴 和義
  21. 1997年, Neurosteroids in the avian brain. , Frontiers in environmental and metabolic endocrinology= Burdwan Press, 1997年, 単行本(学術書), 共著, 浮穴 和義
  22. 1997年, P450scc activity in the brain. , Perspectives in avian endocrinology= Journal of Endocrinology Ltd., 1997年, 単行本(学術書), 共著, 浮穴 和義
  23. 1996年, Gene structures of the GGNG-peptides derived from annelida and the gene products. , Peptide Chemistry 1995= Protein Research Foundation, 1996年, 単行本(学術書), 共著, 浮穴 和義

招待講演、口頭・ポスター発表等

  1. 2018年07月, 招待, 英語
  2. 日本動物学会大会, 2019年09月, 招待, 日本語
  3. ペプチド・ホルモン研究会, 2018年08月, 招待, 日本語
  4. 食欲・食嗜好研究会, 招待, 日本語

受賞

  1. 2009年09月, 平成21年度日本動物学会奨励賞, 日本動物学会, 系統発生学的見地からの神経ペプチドの同定と生理機能解析
  2. 2016年12月10日, 平成28年度日本比較内分泌学会 奨励賞, 日本比較内分泌学会会長

外部資金

競争的資金等の採択状況

  1. イノベーション創出基礎的研究推進事業, 家禽における新規脳内摂食調節因子の機能解明とその利用, 2011年07月29日, 2014年03月31日
  2. 科学研究費助成事業(基盤研究(B)), 視床下部で発見した分泌タンパク質の生理的意義と作用機序の解明, 2014年, 2016年
  3. 科学研究費助成事業(新学術領域研究(研究領域提案型)), 視床下部で発見した新規遺伝子は脂肪蓄積の負のメディエーターか?, 2013年, 2014年
  4. 科学研究費助成事業(挑戦的萌芽研究), 視床下部で新たに発見した神経ペプチドの受容体探索, 2011年, 2012年
  5. 科学研究費助成事業(新学術領域研究(研究領域提案型)), 肥満における新規摂食調節関連遺伝子の機能解明, 2011年, 2012年
  6. 科学研究費助成事業(若手研究(A)), 視床下部で見出した新規摂食関連遺伝子及び翻訳産物の生理機能解明, 2010年, 2013年
  7. 科学研究費助成事業(若手研究(B)), 鳥類ウズラにおける視床下部神経ペプチド(GnIH)による自律神経調節機構の解明, 2008年, 2009年
  8. 科学研究費助成事業(若手研究(B)), 鳥類で見出した新規視床下部ホルモンGnIHのレセプターの局在と生理的変動, 2005年, 2006年
  9. 科学研究費助成事業(若手研究(B)), 鳥類で見出された新規視床下部ホルモンGnIHのレセプターの同定と作用機序の解析, 2003年, 2004年
  10. 科学研究費助成事業(挑戦的萌芽研究), 新規視床下部小タンパク質の標的細胞及び受容体の同定, 2016年, 2017年
  11. 科学研究費助成事業(挑戦的研究(萌芽)), サルコペニア肥満モデル動物の確立と病態解明, 2018年, 2019年

社会活動

委員会等委員歴

  1. 理事, 2016年09月, 2020年09月, 公益社団法人日本動物学会
  2. 日本学術会議連携会員, 2017年10月, 2023年09月, 日本学術会議
  3. 非常勤講師, 2019年04月, 2020年03月, 大分大学
  4. 2019年01月, 2020年12月, 日本比較内分泌学会

学術会議等の主催

  1. 中国四国動物生理シンポジウム

学術雑誌論文査読歴

  1. 2018年, 編集員
  2. 2018年, 編集員
  3. 2018年, その他
  4. 2018年, その他
  5. 2018年, その他
  6. 2018年, その他
  7. 2018年, その他
  8. 2018年, 比較内分泌学, 編集員