卜部 祐司YUJI URABE

Last Updated :2022/07/01

所属・職名
病院(医) 寄附講座准教授
メールアドレス
beyan13hiroshima-u.ac.jp

基本情報

学位

  • 博士(医学) (広島大学)

研究分野

  • 医歯薬学 / 内科系臨床医学 / 消化器内科学

教育活動

授業担当

  1. 2022年, 学部専門, 通年, 器官・システム病態制御学I
  2. 2022年, 学部専門, 集中, 臨床実習入門プログラム
  3. 2022年, 学部専門, 集中, 医学研究実習
  4. 2022年, 学部専門, 集中, 臨床実習I
  5. 2022年, 学部専門, 集中, 臨床実習II
  6. 2022年, 学部専門, セメスター(前期), 内科学I
  7. 2022年, 学部専門, 通年, 器官・システム病態制御学I
  8. 2022年, 学部専門, 集中, 臨床実習入門プログラム
  9. 2022年, 学部専門, 集中, 医学研究実習
  10. 2022年, 学部専門, 集中, 臨床実習I
  11. 2022年, 学部専門, 集中, 臨床実習II
  12. 2022年, 学部専門, セメスター(前期), 内科学I

研究活動

学術論文(★は代表的な論文)

  1. Impact of revisions of the JSCCR guidelines on the treatment of T1 colorectal carcinomas in Japan, ZEITSCHRIFT FUR GASTROENTEROLOGIE, 53巻, 4号, pp. 291-301, 201504
  2. ★, A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population., Hum Mol Genet., 5巻, pp. 3884-3892
  3. HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study., Plos One, 20巻, e84226号
  4. Clinical outcomes of endoscopic submucosal dissection for superficial Barrett's adenocarcinoma., Gastrointest Endosc., 80巻, pp. 239-45, 2014
  5. ★, A genome-wide association study of HCV induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at MHC region., J Hepatol, 58巻, pp. 875-882, 2013
  6. ★, A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1., Plos Genetics, 8巻, pp. e1002541, 2012
  7. ★, A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population, Nature genetics, 44巻, pp. 430-434, 2012
  8. ★, Genome-wide association study identifies asusceptibility locus for HCV-induced hepatocellular carcinoma., Nat Genet, 43巻, pp. 455-458, 2011
  9. ★, Advantages of endoscopic submucosal dissection versus endoscopic oblique aspiration mucosectomy for superficial esophageal tumors., J Gastroenterol Hepatol, 26巻, pp. 275-80, 2011
  10. ★, Metachronous multiple esophageal squamous cell carcinomas and Lugol-voiding lesions after endoscopic mucosal resection., Endoscopy, 41巻, pp. 304-9, 2009
  11. ADH1B and ALDH2 are associated with metachronous SCC after endoscopic submucosal dissection of esophageal squamous cell carcinoma, CANCER MEDICINE, 5巻, 7号, pp. 1397-1404, JUL 2016
  12. Risk factors for esophageal stenosis after entire circumferential endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 30巻, 9号, pp. 4049-4056, SEP 2016
  13. Clinicopathologic and endoscopic features of early-stage colorectal serrated adenocarcinoma, BMC GASTROENTEROLOGY, 17巻, DEC 12 2017
  14. Serial profiling of circulating tumor DNA for optimization of anti-VEGF chemotherapy in metastatic colorectal cancer patients, INTERNATIONAL JOURNAL OF CANCER, 142巻, 7号, pp. 1418-1426, APR 1 2018
  15. Evaluation of the visibility of early gastric cancer using linked color imaging and blue laser imaging, BMC GASTROENTEROLOGY, 17巻, DEC 8 2017
  16. Curative Criteria After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinomas., Dig Dis Sci., 63巻, pp. 1605-1612
  17. Clinical Usefulness of the VS Classification System Using Magnifying Endoscopy with Blue Laser Imaging for Early Gastric Cancer., Gastroenterol Res Pract.
  18. Diagnosis of superficial esophageal squamous cell carcinoma invasion depth before endoscopic submucosal dissection, DISEASES OF THE ESOPHAGUS, 31巻, 7号, 201807
  19. Magnifying Endoscopy with Narrow Band Imaging in Estimating the Invasion Depth of Superficial Esophageal Squamous Cell Carcinomas, DIGESTION, 98巻, 4号, pp. 249-256, 2018
  20. Early-stage serrated adenocarcinomas are divided into several molecularly distinct subtypes, PLOS ONE, 14巻, 2号, 20190220
  21. Construction of a risk model for the development of metachronous squamous cell carcinoma after endoscopic resection of esopahageal squamous cell carcinoma, ESOPHAGUS, 16巻, 2号, pp. 141-146, 201904
  22. Helicobacter suis infection is associated with nodular gastritis-like appearance of gastric mucosa-associated lymphoid tissue lymphoma, CANCER MEDICINE, 8巻, 9号, pp. 4370-4379, 201908
  23. Genomic characterization of early-stage esophageal squamous cell carcinoma in a Japanese population., Oncotarget, 10巻, 41号, pp. 4139-4148, 2019
  24. A case of primary malignant melanoma of the esophagus with a widely expanded surface area., Clin J Gastroenterol., 2019
  25. Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy, JOURNAL OF GASTROENTEROLOGY, 54巻, 10号, pp. 907-915, 201910
  26. A new method for intraluminal gastrointestinal stromal tumor resection using laparoscopic seromuscular dissection technique, DIGESTIVE SURGERY, 27巻, 6号, pp. 461-465
  27. A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population, JOURNAL OF HUMAN GENETICS, 58巻, 9号, pp. 588-593, 2013
  28. Identification of a functional variant in the MICA promoter which regulates MICA expression and increases HCV-related hepatocellular carcinoma risk, PLOS ONE, 8巻, 4号, pp. PLOS ONE
  29. Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma, PLOS ONE, 7巻, 9号, pp. e44743, 2012
  30. Clinical and genomic characteristics of mucosal signet-ring cell carcinoma in Helicobacter pylori-uninfected stomach, BMC GASTROENTEROLOGY, 20巻, 1号, pp. 243, 2020
  31. Usefulness of linked color imaging in the early detection of superficial esophageal squamous cell carcinomas, ESOPHAGUS
  32. Clinical features of pharyngeal intraepithelial neoplasias and outcomes of treatment by endoscopic submucosal dissection, 76巻, 6号, pp. 1095-1103, 2012
  33. Meta-analysis used to identify factors associated with the effectiveness of proton pump inhibitors against non-erosive reflux disease, 24巻, 8号, pp. 1326-1332, 2009
  34. Defensive medicine practices among gastroenterologists in Japan, WORLD JOURNAL OF GASTROENTEROLOGY, 12巻, 47号, pp. 7671-7675

外部資金

競争的資金等の採択状況

  1. 内視鏡医学研究振興財団 研究助成B, 癌ゲノム時代のpost-colonoscopy colorectal cancer(PCCRC)の検討, 2019年, 2021年
  2. 科学研究費助成事業(若手研究(B)), 炎症性腸疾患治療薬の薬理遺伝学研究-オーダーメイド医療にむけて-, 2013年, 2015年
  3. 科学研究費助成事業(若手研究(B)), ヘリコバクター・ピロリ菌除菌後胃癌の克服に向けて
  4. ブリストル・マイヤーズ株式会社研究基金, 「ゲノム解析による大腸T1癌の転移バイオマーカーの探索」, 2015年, 2018年
  5. 科学研究費助成事業(若手研究(B)), ヘリコバクター・ピロリ菌除菌後胃癌の克服に向けて, 2016年, 2017年
  6. 「のぞみH基金」, post-colonoscopy colorectal cancer (PCCRC)に対する遺伝学的検討, 2019年01月01日, 2020年12月31日
  7. 武田医学振興財団2019年医学系研究助成(がん領域・臨床), ヘリコバクター・ピロリ除菌後胃癌に発生する低異型度上皮の発生 メカニズムの解明, 2020年01月01日, 2021年12月31日
  8. 土谷記念医学振興基金, 大腸癌発癌におけるserrated pathwayの解明, 2019年, 2020年