卜部 祐司YUJI URABE

Last Updated :2021/05/10

所属・職名
病院未来医療センター 助教
メールアドレス
beyan13hiroshima-u.ac.jp

基本情報

学位

  • 博士(医学) (広島大学)

教育活動

授業担当

  1. 2021年, 学部専門, 集中, 症候診断治療学
  2. 2021年, 学部専門, 集中, 臨床実習入門プログラム
  3. 2021年, 学部専門, セメスター(前期), 内科学I

研究活動

学術論文(★は代表的な論文)

  1. A case of primary malignant melanoma of the esophagus with a widely expanded surface area., Clin J Gastroenterol., 2019
  2. ★, A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population, Nature genetics, 44巻, pp. 430-434, 2012
  3. ★, A genome-wide association study of HCV induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at MHC region., J Hepatol, 58巻, pp. 875-882, 2013
  4. ★, A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population., Hum Mol Genet., 5巻, pp. 3884-3892
  5. ★, A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1., Plos Genetics, 8巻, pp. e1002541, 2012
  6. A new method for intraluminal gastrointestinal stromal tumor resection using laparoscopic seromuscular dissection technique, DIGESTIVE SURGERY, 27巻, 6号, pp. 461-465
  7. A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population, JOURNAL OF HUMAN GENETICS, 58巻, 9号, pp. 588-593, 2013
  8. ADH1B and ALDH2 are associated with metachronous SCC after endoscopic submucosal dissection of esophageal squamous cell carcinoma, CANCER MEDICINE, 5巻, 7号, pp. 1397-1404, JUL 2016
  9. ★, Advantages of endoscopic submucosal dissection versus endoscopic oblique aspiration mucosectomy for superficial esophageal tumors., J Gastroenterol Hepatol, 26巻, pp. 275-80, 2011
  10. Clinical Usefulness of the VS Classification System Using Magnifying Endoscopy with Blue Laser Imaging for Early Gastric Cancer., Gastroenterol Res Pract.
  11. Clinical and genomic characteristics of mucosal signet-ring cell carcinoma in Helicobacter pylori-uninfected stomach, BMC GASTROENTEROLOGY, 20巻, 1号, pp. 243, 2020
  12. Clinical features of pharyngeal intraepithelial neoplasias and outcomes of treatment by endoscopic submucosal dissection, 76巻, 6号, pp. 1095-1103, 2012
  13. Clinical outcomes of endoscopic submucosal dissection for superficial Barrett's adenocarcinoma., Gastrointest Endosc., 80巻, pp. 239-45, 2014
  14. Clinicopathologic and endoscopic features of early-stage colorectal serrated adenocarcinoma, BMC GASTROENTEROLOGY, 17巻, DEC 12 2017
  15. Construction of a risk model for the development of metachronous squamous cell carcinoma after endoscopic resection of esopahageal squamous cell carcinoma, ESOPHAGUS, 16巻, 2号, pp. 141-146, 201904
  16. Curative Criteria After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinomas., Dig Dis Sci., 63巻, pp. 1605-1612
  17. Defensive medicine practices among gastroenterologists in Japan, WORLD JOURNAL OF GASTROENTEROLOGY, 12巻, 47号, pp. 7671-7675
  18. Diagnosis of superficial esophageal squamous cell carcinoma invasion depth before endoscopic submucosal dissection, DISEASES OF THE ESOPHAGUS, 31巻, 7号, 201807
  19. Early-stage serrated adenocarcinomas are divided into several molecularly distinct subtypes, PLOS ONE, 14巻, 2号, 20190220
  20. Evaluation of the visibility of early gastric cancer using linked color imaging and blue laser imaging, BMC GASTROENTEROLOGY, 17巻, DEC 8 2017
  21. ★, Genome-wide association study identifies asusceptibility locus for HCV-induced hepatocellular carcinoma., Nat Genet, 43巻, pp. 455-458, 2011
  22. Genomic characterization of early-stage esophageal squamous cell carcinoma in a Japanese population., Oncotarget, 10巻, 41号, pp. 4139-4148, 2019
  23. Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy, JOURNAL OF GASTROENTEROLOGY, 54巻, 10号, pp. 907-915, 201910
  24. HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study., Plos One, 20巻, e84226号
  25. Helicobacter suis infection is associated with nodular gastritis-like appearance of gastric mucosa-associated lymphoid tissue lymphoma, CANCER MEDICINE, 8巻, 9号, pp. 4370-4379, 201908
  26. Identification of a functional variant in the MICA promoter which regulates MICA expression and increases HCV-related hepatocellular carcinoma risk, PLOS ONE, 8巻, 4号, pp. PLOS ONE
  27. Impact of revisions of the JSCCR guidelines on the treatment of T1 colorectal carcinomas in Japan, ZEITSCHRIFT FUR GASTROENTEROLOGIE, 53巻, 4号, pp. 291-301, 201504
  28. Magnifying Endoscopy with Narrow Band Imaging in Estimating the Invasion Depth of Superficial Esophageal Squamous Cell Carcinomas, DIGESTION, 98巻, 4号, pp. 249-256, 2018
  29. Meta-analysis used to identify factors associated with the effectiveness of proton pump inhibitors against non-erosive reflux disease, 24巻, 8号, pp. 1326-1332, 2009
  30. ★, Metachronous multiple esophageal squamous cell carcinomas and Lugol-voiding lesions after endoscopic mucosal resection., Endoscopy, 41巻, pp. 304-9, 2009
  31. Risk factors for esophageal stenosis after entire circumferential endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 30巻, 9号, pp. 4049-4056, SEP 2016
  32. Serial profiling of circulating tumor DNA for optimization of anti-VEGF chemotherapy in metastatic colorectal cancer patients, INTERNATIONAL JOURNAL OF CANCER, 142巻, 7号, pp. 1418-1426, APR 1 2018
  33. Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma, PLOS ONE, 7巻, 9号, pp. e44743, 2012
  34. Usefulness of linked color imaging in the early detection of superficial esophageal squamous cell carcinomas, ESOPHAGUS

外部資金

競争的資金等の採択状況

  1. 癌ゲノム時代のpost-colonoscopy colorectal cancer(PCCRC)の検討, 2019年, 2021年
  2. 科学研究費助成事業(若手研究(B)), 炎症性腸疾患治療薬の薬理遺伝学研究-オーダーメイド医療にむけて-, 2013年, 2015年
  3. 科学研究費助成事業(若手研究(B)), ヘリコバクター・ピロリ菌除菌後胃癌の克服に向けて
  4. ブリストル・マイヤーズ株式会社研究基金, 「ゲノム解析による大腸T1癌の転移バイオマーカーの探索」, 2015年, 2018年
  5. 科学研究費助成事業(若手研究(B)), ヘリコバクター・ピロリ菌除菌後胃癌の克服に向けて, 2016年, 2017年
  6. 「のぞみH基金」, post-colonoscopy colorectal cancer (PCCRC)に対する遺伝学的検討, 2019年01月01日, 2020年12月31日
  7. 武田医学振興財団2019年医学系研究助成(がん領域・臨床), ヘリコバクター・ピロリ除菌後胃癌に発生する低異型度上皮の発生 メカニズムの解明, 2020年01月01日, 2021年12月31日
  8. 土谷記念医学振興基金, 大腸癌発癌におけるserrated pathwayの解明, 2019年, 2020年