花之内 健仁TAKEHITO HANANOUCHI

Last Updated :2025/01/07

所属・職名
広島大学 学術・社会連携室 オープンイノベーション本部　産学連携部 バイオデザイン部門　教授
メールアドレス
takehitohiroshima-u.ac.jp

基本情報

学位

  • 博士（医学）　(大阪大学)
  • 博士（医学）　(大阪大学)

研究キーワード

  • 定量的MRI
  • 3D プリンティング・３Dバイオプリンティング
  • バイオメカニクス
  • 運動器リハビリテーション
  • 股関節鏡治療
  • 再生医療（整形外科分野）
  • 人工関節
  • 関節外科
  • 医工学

教育活動

授業担当

  1. 2024年, 修士課程・博士課程前期, セメスター（前期）, バイオデザイン概論AⅠ
  2. 2024年, 修士課程・博士課程前期, セメスター（後期）, バイオデザイン概論AⅡ
  3. 2024年, 修士課程・博士課程前期, セメスター（前期）, バイオデザイン概論BⅠ
  4. 2024年, 修士課程・博士課程前期, セメスター（後期）, バイオデザイン概論BⅡ
  5. 2024年, 修士課程・博士課程前期, セメスター（前期）, バイオデザイン演習Ⅰ
  6. 2024年, 修士課程・博士課程前期, セメスター（後期）, バイオデザイン演習Ⅱ
  7. 2024年, 修士課程・博士課程前期, 通年, バイオデザイン実習

研究活動

学術論文（★は代表的な論文）

  1. Horseradish Peroxidase-Mediated Bioprinting via Bioink Gelation by Alternately Extruded Support Material, ACS BIOMATERIALS SCIENCE & ENGINEERING, 9巻, 10号, pp. 5804-5812, 20230922
    DOIを用いた論文検索結果へのリンク
  2. Determining the Relationship between Mechanical Properties and Quantitative Magnetic Resonance Imaging of Joint Soft Tissues Using Patient-Specific Templates, BIOENGINEERING-BASEL, 10巻, 9号, 202309
    DOIを用いた論文検索結果へのリンク
  3. Horseradish Peroxidase-Mediated Bioprinting via Bioink Gelation by Alternately Extruded Support Material, ACS Biomaterials Science & Engineering, 9巻, 10号, pp. 5804-5812, 20230922
  4. Determining the Relationship between Mechanical Properties and Quantitative Magnetic Resonance Imaging of Joint Soft Tissues Using Patient-Specific Templates., Bioengineering, 10巻, 9号, pp. 1-9, 202309
  5. Evaluation of Hallux Valgus Using Rotational Moment of Midfoot Measured by a Three-dimensional Foot Scanner: a Cross-sectional Observational Study, Advanced Biomedical Engineering, 12巻, pp. 154-162, 202306
  6. The Relationship between Heel Fat Pad Thickness and Flexibility and Physical Demographics, Fortune Journal of Health Sciences, 05巻, 04号, pp. 581-588, 202212
  7. Validation of a method to measure T2 value from the color mapping by hue value, Current Medical Imaging Formerly Current Medical Imaging Reviews, 18巻, 20220907
  8. 第3章 関節外科治療におけるバイオプリンティング技術への期待, バイオプリンティングの技術と市場 （シー・エム・シー出版）監修：境 慎司 ISBN：978-4-7813-1680-2, pp. 88-97, 202208
  9. 空気圧押し出し式 3D バイオプリンタを用いた超音波ゼリーの 試用バイオインクとしての印刷評価, 日本機械学会論文集, 88巻, 907号, pp. p. 21-00151, 202203
  10. 3Dバイオプリンタを用いた超音波検査用ゼリーの粘性評価, 整形外科, 202202
  11. The Resistance Force of the Anterior Cruciate Ligament during Pull Probing Is Related to the Mechanical Property., Bioengineering, 2022
  12. Correlation between the elastic modulus of anterior cruciate ligament (ACL) and quantitative ultrashort echo time (UTE) magnetic resonance imaging., Journal of Orthopaedic Research, 2022
  13. 関節治療におけるバイオプリンティング技術への期待, BIO INDUSTRY, 38巻, 10号, pp. 49-57, 202110
  14. Comparison of Labrum Resistance Force while Pull-Probing In Vivo and Cadaveric Hips, Biomimetics, 6巻, 2号, pp. 35-35, 20210531
  15. 3Dバイオプリンタ―でつなぐ関節治療の再生医工学研究と関節鏡手術シミュレータ研究の融合, 大阪産業大学論集 自然科学編, 131巻, pp. 39-46, 202103
  16. A Useful Combination of Quantitative Ultrashort Echo Time MR Imaging and a Probing Device for Biomechanical Evaluation of Articular Cartilage., Biosensors, 11巻, 2号, 20210217
  17. Inclusion of the Acetabular Labrum Reduces Simulated Range of Motion of the Hip Compared With Bone Contact Models., Arthroscopy, sports medicine, and rehabilitation, 2巻, 6号, pp. e779-e787, 202012
  18. A Probing Device for Quantitatively Measuring the Mechanical Properties of Soft Tissues during Arthroscopy., Journal of visualized experiments : JoVE, 159号, 20200501
  19. Sclerotic lesions of the femoral head-neck junction for diagnosis of femoroacetabular impingement, J Orthop Surg (Hong Kong), 28巻, 2号, 202004
  20. Quantitative evaluation of capsular and labral resistances in the hip joint using a probing device, Biomed Mater Eng., 30巻, 3号, pp. 333-340, 201904
  21. Morphological abnormalities of the femur in the dysplastic hip. Relation between femur en acetabulum, Acta Orthop Belg., 84巻, 3号, pp. 307-315, 201809
  22. Hip Arthroscopy Capsular Closure: The Figure of Eight Technique. Arthroscopy Technique, Arthrosc Tech., 6巻, 2号, pp. e505-e509, 2017
  23. Evaluation of the efficacy of Ajuga decumbens extract supplement in individuals with knee discomfort associated with physical activity: A randomized, double-blind, placebo-controlled study, Exp Ther Med, 2017
  24. ハンディ3DスキャナKinectを用いた下肢切断端スキャンの精度検証, Medical Imaging Technology, 34巻, 2号, pp. 103-105, 201603
  25. Sagittal gap balancing with the concept of a single radius femoral component in posterior cruciate sacrificing total knee arthroplasty with patient-specific instrumentation, INTERNATIONAL ORTHOPAEDICS, 39巻, 4号, pp. 659-665, 201504
  26. Prophylactic bioactive screw fixation as an alternative augmentation for femoroplasty, BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK, 60巻, 2号, pp. 165-169, 201504
  27. Evaluation of a quantitative probing to assess condition of soft tissue during arthroscopic surgery for regenerative medicine., J Tissue Eng Regen Med, 8巻, pp. 467-468, 201406
  28. Effect of a Modular Femoral Neck System on Femoral Anteversion and Range of Motion before Implant Impingement, Journal of Contemporary Orthopaedic Research, 2014
  29. Patient-specific Instrumentation for Acetabular Cup Orientation: Accuracy Analysis in a Pre-clinical Study., Journal of Contemporary Orthopaedic Research, 2014
  30. 人工関節 画像評価 THA後の下肢周囲径の変化量とX線上の下肢周囲幅の関連について, 日本人工関節学会誌, 43巻, pp. 623-624, 201312
  31. 人工膝関節全置換術後に発症した皮膚壊死に対し持続陰圧閉鎖療法を施行した1例, 整形外科, 64巻, 13号, pp. 1387-1389, 201312
  32. Accuracy of angle and position of the cup using computed tomography-based navigation systems in total hip arthroplasty, COMPUTER AIDED SURGERY, 18巻, 5-6号, pp. 187-194, 2013
  33. 骨粗鬆症患者の大腿骨頚部骨折に対する骨補填材料充填による外科的予防治療(Femoroplasty)の確立, Osteoporosis Japan, 201212
  34. Anterior Impingement Test for Labral Lesions Has High Positive Predictive Value, CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 470巻, 12号, pp. 3524-3529, 201212
  35. The intraoperative gap difference (flexion gap minus extension gap) is altered by insertion of the trial femoral component, KNEE, 19巻, 5号, pp. 601-605, 201210
  36. Orthopaedic surgical technique 股関節 セメントレス人工股関節置換術, 整形外科Surgical Technique, 1巻, 3号, pp. 285-304, 201108
  37. In vivo three-dimensional analysis of uncovered area of the acetabular component in THA., International Society for Computer Assisted Orthopaedic Surgery, pp. 492-494, 201006
  38. Tailor-made Surgical Guide Reduces Incidence of Outliers of Cup Placement, CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 468巻, 4号, pp. 1088-1095, 201004
  39. The Vascular Network in the Femoral Head and Neck After Hip Resurfacing, JOURNAL OF ARTHROPLASTY, 25巻, 1号, pp. 146-151, 201001
  40. ナビゲーションシステムを用いたFemoroplasty（骨補填材料充填による大腿骨頚部骨折に対する予防的治療）の手術手技効果の検討, 日本コンピュータ外科学会誌, 11巻, 3号, pp. 182-183, 200911
  41. Tailor Made Surgical Guide Based On Rapid Prototyping Technique Reduces The Learning Curve For Cup Insertion in THA., International Society for Computer Assisted Orthopaedic Surgery, pp. 152-154, 200906
  42. Tailor-made surgical guide based on rapid prototyping technique for cup insertion in total hip arthroplasty, INTERNATIONAL JOURNAL OF MEDICAL ROBOTICS AND COMPUTER ASSISTED SURGERY, 5巻, 2号, pp. 164-169, 200906
  43. Comparison of navigation accuracy in THA between the mini-anterior and -posterior approaches, INTERNATIONAL JOURNAL OF MEDICAL ROBOTICS AND COMPUTER ASSISTED SURGERY, 5巻, 1号, pp. 20-25, 200903
  44. Logitudinal analysis of Progression in Hip osteoarthritis over 6 years, using a computational automated algorithm., Osteoarthritis and Cartilage, 17巻, pp. 234-235, 200902
  45. Surgical guide for acetabular insertion using rapid protptyping technique –in vitro study-, Int J CARS, pp. 243-244, 200806
  46. Extent of osteonecrosis on MRI predicts humeral head collapse, CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 466巻, 5号, pp. 1074-1080, 200805
  47. CT-based planning of a single-radius femoral component in total knee arthroplasty using the ROBODOC system, COMPUTER AIDED SURGERY, 13巻, 1号, pp. 23-29, 200801
  48. Proximal Femoral Bone Mineral Density After Resurfacing Total Hip Arthroplasty and After Standard Stem-Type Cementless Total Hip Arthroplasty, Both Having Similar Neck Preservation and the Same Articulation Type, JOURNAL OF ARTHROPLASTY, 22巻, 8号, pp. 1208-1213, 200712
  49. Effect of robotic milling on periprosthetic bone remodeling, JOURNAL OF ORTHOPAEDIC RESEARCH, 25巻, 8号, pp. 1062-1069, 200708
  50. Preoperative templating of femoral components on plain X-rays: Rotational evaluation with synthetic X-rays on ORTHODOC, Archives of Orthopaedic and Trauma Surgery, 127巻, 5号, pp. 381-385, 200707
  51. Suctioning prevents emboli during insertion of acetabular components without holes, CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 457号, pp. 150-155, 200704
  52. Evaluation of cartilage matrix disorders by T2 relaxation time in patients with hip dysplasia., Osteoarthritis Cartilage, 2007
  53. Effect of localizer grade on accuracy of surface registration with CT-based navigation system for total hip arthroplasty, Int J CARS, pp. 491-492, 200606
  54. 表面置換型人工股関節全置換術におけるナビゲーション‐レーザーガイダンスシステム, 日本人工臓器学会誌, 35巻, pp. 346-347, 200603
  55. Core Biopsy and Decompression., 骨・関節・靭帯, 18巻, 12号, pp. 1099-1104, 200512
  56. Huge pelvic mass secondary to wear debris causing ureteral obstruction, JOURNAL OF ARTHROPLASTY, 20巻, 7号, pp. 946-949, 200510
  57. Wear analysis of retrieved ceramic-on-ceramic articulations in total hip arthroplasty: Femoral head makes contact with the rim of the socket outside of the bearing surface, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 73B巻, 2号, pp. 301-307, 200505