桑井 寿雄TOSHIO KUWAI

Last Updated :2025/08/07

所属・職名
病院（医）　寄附講座教授
メールアドレス
kuwaihiroshima-u.ac.jp

基本情報

学位

  • 博士（医学）　(広島大学)

研究分野

  • 医歯薬学 / 内科系臨床医学 / 消化器内科学

所属学会

  • 日本内科学会
  • 日本消化器内視鏡学会
  • 日本消化器病学会
  • 日本消化管学会
  • 日本消化器がん検診学会
  • 日本大腸検査学会
  • 日本腹部救急医学会
  • 日本大腸肛門病学会
  • 日本癌学会
  • 米国消化器内視鏡学会
  • 欧州消化器内視鏡学会
  • 米国癌学会

教育活動

授業担当

  1. 2025年, 学部専門, 通年, 組織細胞機能学

研究活動

学術論文（★は代表的な論文）

  1. 【症例から学ぶ咽頭・食道ESD】表在型食道扁平上皮癌のESD　左壁の病変で水没して視野が得られない, 消化器内視鏡, 202408
  2. 潰瘍性大腸炎の内視鏡所見, 胃と腸, 59巻, 10号, pp. 1390-1399, 202410
  3. Efficiency of Real-time Computer-aided Polyp Detection during Surveillance Colonoscopy: A Pilot Study, JOURNAL OF THE ANUS RECTUM AND COLON, 9巻, 1号, pp. 127-133, 2025
    DOIを用いた論文検索結果へのリンク
  4. 大腸内視鏡観察法の基本知識, 消化器内視鏡, 37巻, 3号, pp. 285-294, 2025
  5. Serrated polyposis syndrome に合併した上行結腸T1癌の1例, 胃と腸, 60巻, 2号, 20250225
  6. 鋸歯状癌に関する最新知見, 胃と腸　　, 60巻, 2号, 20250225
  7. Clinical usefulness of hybrid endoscopic submucosal dissection for T1b colorectal carcinomas ≤20 mm to ensure adequate vertical margins, DEN OPEN, 5巻, 1号, 202504
    DOIを用いた論文検索結果へのリンク
  8. A Proton Pump Inhibitor Independently Elevates Gastrin Levels as a Marker for Metachronous Gastric Cancer After Endoscopic Submucosal Dissection, JOURNAL OF CLINICAL MEDICINE, 13巻, 21号, 202411
    DOIを用いた論文検索結果へのリンク
  9. Comparative prediction of lymph node metastasis in pT1 colorectal cancer among Western and Japanese guidelines, FRONTIERS IN ONCOLOGY, 14巻, 20241031
    DOIを用いた論文検索結果へのリンク
  10. Clinicopathologic Features of Early Gastric Cancer after Heli-cobacter pylori Eradication in Japanese Patients: Comparative Study between Early (<10 Years) and Late (>10 Years) Onset, CANCERS, 16巻, 18号, 202409
    DOIを用いた論文検索結果へのリンク
  11. Radiation Exposure with Self-Expandable Metallic Stent versus Transanal Decompression Tube for Malignant Colorectal Obstruction: A Post Hoc Propensity Score Matched Analysis, JOURNAL OF CLINICAL MEDICINE, 13巻, 19号, 202410
    DOIを用いた論文検索結果へのリンク
  12. A New Self-Expandable Metallic Stent with Low Axial Force and a High Axial Force Zero-Border Shows a Very Low Perforation Rate in Malignant Colorectal Obstruction: A Japanese Multicenter Prospective Study, JOURNAL OF CLINICAL MEDICINE, 13巻, 17号, 202409
    DOIを用いた論文検索結果へのリンク
  13. 内視鏡的に切除し得た最大径55mmの大腸脂肪腫の1例, 広島医学, 1998
  14. How Does Omitting Additional Surgery After Local Excision Affect the Prognostic Outcome of Patients With High-risk T1 Colorectal Cancer?, Annals of surgery, 279巻, 2号, 2024
  15. Outcomes of Metastatic and Unresectable Small Bowel Adenocarcinoma in Japan According to the Treatment Strategy: A Nationwide Observational Study., JCO global oncology, 10巻, 2024
  16. Treatment Decision for Locally Resected T1 Colorectal Carcinoma-Verification of the Japanese Guideline Criteria for Additional Surgery Based on Long-Term Clinical Outcomes., The American journal of gastroenterology, 2024
  17. Clinicopathological features and prognosis of primary small bowel adenocarcinoma: a large multicenter analysis of the JSCCR database in Japan., Journal of gastroenterology, 59巻, 5号, 2024
  18. High-grade pancreatic intraepithelial neoplasia diagnosed based on changes in magnetic resonance cholangiopancreatography findings: A case report., World journal of clinical cases, 12巻, 8号, 2024
  19. Long-term outcomes of additional surgery after endoscopic resection versus primary surgery for T1 colorectal cancer., The American journal of gastroenterology, 2024
  20. A feasibility study comparing gel immersion endoscopic resection and underwater endoscopic mucosal resection for superficial nonampullary duodenal epithelial tumors., Endoscopy, 55巻, 3号, 2023
  21. Endoscopic submucosal dissection for tumors involving the ileocecal valve with extension into the terminal ileum: a multicenter study from the Hiroshima GI Endoscopy Research Group., Surgical endoscopy, 37巻, 2号, 2023
  22. Proportion of Neutrophils in White Blood Cells as a Useful Marker for Predicting Bacteremic Acute Cholangitis., Internal medicine (Tokyo, Japan), 62巻, 19号, 2023
  23. Metastatic pancreatic ductal adenocarcinoma followed by a fatal diffuse large B-cell lymphoma: A rare case report and literature review., Medicine, 102巻, 12号, 2023
  24. Immunoglobulin G4-related Disease Presenting as a Gastric Ulcer with Repeated Exacerbations and Remissions., Journal of gastrointestinal and liver diseases : JGLD, 32巻, 1号, 2023
  25. Clinical features and images of malignant lymphoma localized in the pancreatic head to differentiate from pancreatic ductal adenocarcinoma: a case series study., BMC gastroenterology, 23巻, 1号, 2023
  26. A Japanese Prospective, Multicenter Study of Colonic Stenting for Palliation Using a High Axial Force Self-Expandable Metal Stent for Malignant Large Bowel Obstruction in 200 Patients., Journal of clinical medicine, 12巻, 15号, 2023
  27. Efficacy of a novel integrated biliary stent and nasobiliary catheter system for accidental tube deviation in biliary drainage., Endoscopy international open, 11巻, 9号, 2023
  28. Usefulness of an ultrathin endoscope for guidewire insertion during stent-in-stent placement., VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy, 8巻, 12号, 2023
  29. Medical radiation exposure during gastrointestinal enteral metallic stent placement: Post hoc analysis of the REX-GI study., JGH open : an open access journal of gastroenterology and hepatology, 7巻, 12号, 2023
  30. A case of pancreatic adenosquamous carcinoma with direct invasion to the gastrointestinal tract through the retention cyst wall: A rare case report., JGH open : an open access journal of gastroenterology and hepatology, 7巻, 12号, 2023
  31. Giant Peutz-Jeghers-type polyp with anal prolapse resected using endoscopic submucosal dissection., Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 54巻, 4号, 2022
  32. Indications and outcomes of colorectal hybrid endoscopic submucosal dissection: a large multicenter 10-year study., Surgical endoscopy, 36巻, 3号, 2022
  33. Long-term outcomes of standardized colonic stenting using WallFlex as a bridge to surgery: Multicenter prospective cohort study., Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 34巻, 4号, 2022
  34. High Annexin A10 expression is correlated with poor prognosis in pancreatic ductal adenocarcinoma., Histology and histopathology, 37巻, 3号, 2022
  35. Diagnostic Reference Levels for Fluoroscopy-guided Gastrointestinal Procedures in Japan from the REX-GI Study: A Nationwide Multicentre Prospective Observational Study., The Lancet regional health. Western Pacific, 20巻, 2022
  36. A study for every second day administration of vonoprazan for maintenance treatment of erosive GERD (ESD von GERD): a multicenter randomized cross-over study., Journal of gastroenterology, 57巻, 3号, 2022
  37. Efficacy and safety comparison of scissor-type knives with needle-type knives for colorectal endoscopic submucosal dissection: a post-hoc propensity score-matched analysis (with videos)., Gastrointestinal endoscopy, 96巻, 1号, 2022
  38. The Deployment of a Newly Developed Proximal Release-Type Colonic Stent Is Feasible for Malignant Colorectal Obstruction near the Anal Verge: A Single-Center Preliminary Study., Journal of clinical medicine, 11巻, 6号, 2022
  39. Transcriptomic Analysis of Annexin A10 and Chemosensitivity in Gastric Adenocarcinoma Cells., Anticancer research, 42巻, 4号, 2022
  40. Characteristics of colorectal neuroendocrine tumors in patients prospectively enrolled in a Japanese multicenter study: a first report from the C-NET STUDY., Journal of gastroenterology, 57巻, 8号, 2022
  41. Factors for conversion risk of colorectal endoscopic submucosal dissection: a multicenter study., Surgical endoscopy, 36巻, 8号, 2022
  42. Advanced gallbladder cancer accompanied with cancer-associated dermatomyositis: A case report and literature review., Medicine, 101巻, 27号, 2022
  43. Potential for replacing warfarin with a direct oral anticoagulant for endoscopic mucosal resection in the colorectum: A multicenter, open-label, randomized controlled trial., DEN open, 2巻, 1号, 2022
  44. Challenges in colonic stenting: Giving up is not an option., Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 34巻, 7号, 2022
  45. Efficacy of a Traction Device for Endoscopic Submucosal Dissection Using a Scissor-Type Knife: A Randomized Controlled Trial., The American journal of gastroenterology, 117巻, 11号, 2022
  46. Long-standing diabetes mellitus increases concomitant pancreatic cancer risk in patients with intraductal papillary mucinous neoplasms., BMC gastroenterology, 22巻, 1号, 2022
  47. Effectiveness of Abdominal Ultrasonography for Improving the Prognosis of Pancreatic Cancer during Medical Checkup: A Single Center Retrospective Analysis., Diagnostics (Basel, Switzerland), 12巻, 12号, 2022
  48. Risk Factors for Delayed Bleeding after Therapeutic Gastrointestinal Endoscopy in Patients Receiving Oral Anticoagulants: A Multicenter Retrospective Study., Digestion, 102巻, 2号, 2021
  49. Zenker's Diverticulum: Can Protocolised Measurements with Barium SWALLOW Predict Severity and Treatment Outcomes? The "Zen-Rad" Study., Dysphagia, 36巻, 3号, 2021
  50. Recurrent pyogenic granuloma successfully treated with endoscopic submucosal dissection four months after endoscopic mucosal resection., Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 53巻, 8号, 2021
  51. Water-assisted colonoscopy: an international modified Delphi review on definitions and practice recommendations., Gastrointestinal endoscopy, 93巻, 6号, 2021
  52. Clinical significance of immunohistochemical lymphovascular evaluation to determine additional surgery after endoscopic submucosal dissection for colorectal T1 carcinoma., International journal of colorectal disease, 36巻, 5号, 2021
  53. Endoscopic resection of local recurrences of diminutive polyps by cold forceps polypectomy., Scandinavian journal of gastroenterology, 56巻, 3号, 2021
  54. Salvage endoscopic submucosal dissection for local residual/recurrent colorectal tumor after endoscopic resection: Large multicenter 10-year study., Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 33巻, 4号, 2021
  55. Annexin A10 Expression Is Associated With Poor Prognosis in Small Bowel Adenocarcinoma., Anticancer research, 41巻, 3号, 2021
  56. A case of intraductal tubulopapillary neoplasm of the pancreas in a branch duct: a rare case report and literature review., BMC gastroenterology, 21巻, 1号, 2021
  57. Hematogenous metastasis to colon from gallbladder cancer., JGH open : an open access journal of gastroenterology and hepatology, 5巻, 5号, 2021
  58. Genomic analysis for the prediction of prognosis in small-bowel cancer., PloS one, 16巻, 5号, 2021
  59. Zenker's peroral endoscopic myotomy (Z-POEM) for recurrent Zenker diverticulum: not so fast!, Endoscopy, 53巻, 7号, 2021
  60. The efficacy of prophylactic clip closure of mucosal defects after colorectal endoscopic submucosal dissection on delayed bleeding., Scandinavian journal of gastroenterology, 56巻, 10号, 2021
  61. Gel immersion endoscopy-facilitated endoscopic mucosal resection of a superficial nonampullary duodenal epithelial tumor: a novel approach., VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy, 6巻, 9号, 2021
  62. Short-Term Outcomes of Colorectal Stenting Using a Low Axial Force Self-Expandable Metal Stent for Malignant Colorectal Obstruction: A Japanese Multicenter Prospective Study., Journal of clinical medicine, 10巻, 21号, 2021
  63. Real-world learning curve analysis of colorectal endoscopic submucosal dissection: a large multicenter study., Surgical endoscopy, 34巻, 8号, 2020
  64. Is Z-POEM for Zenker's the same as POEM for achalasia? Or we are barking up the wrong tree?, Gastrointestinal endoscopy, 91巻, 1号, 2020
  65. Determining the difference in the efficacy and safety of self-expandable metallic stents as a bridge to surgery for obstructive colon cancer among patients in the CROSS 0 group and those in the CROSS 1 or 2 group: a pooled analysis of data from two Japanese prospective multicenter trials., Surgery today, 50巻, 9号, 2020
  66. Multicentre prospective observational study protocol for radiation exposure from gastrointestinal fluoroscopic procedures (REX-GI study)., BMJ open, 10巻, 2号, 2020
  67. Long-term success of flexible endoscopic septal division with the stag beetle knife for Zenker's diverticulum: a tertiary center study., Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 33巻, 11号, 2020
  68. Newly developed self-expandable Niti-S MD colonic metal stent for malignant colonic obstruction., World journal of gastrointestinal surgery, 12巻, 4号, 2020
  69. Newly developed proximal release-type colonic stent placement for malignant lower rectal obstruction., VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy, 5巻, 6号, 2020
  70. Covid-19 pandemic impact on colonoscopy service and suggestions for managing recovery., Endoscopy international open, 8巻, 7号, 2020
  71. [A case of Salmonella bacteremia in an otherwise healthy young man]., Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 117巻, 8号, 2020
  72. Learning curve for endoscopic submucosal dissection of early colorectal neoplasms with a monopolar scissor-type knife: use of the cumulative sum method., Scandinavian journal of gastroenterology, 55巻, 10号, 2020
  73. Carcinoma in situ of the pancreas with fibrosis area around the carcinoma: A case report., Medicine, 99巻, 42号, 2020
  74. Intramucosal Poorly Differentiated Adenocarcinomas Detected in a Patient with Long-Standing Ulcerative Colitis., Case reports in oncology, 13巻, 3号, 2020
  75. [Colitis-associated cancer in ulcerative colitis -pathological condition and chemoprevention]., Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 117巻, 11号, 2020
  76. Loss of Annexin A10 Expression Is Associated with Poor Prognosis in Early Gastric Cancer., Acta histochemica et cytochemica, 53巻, 5号, 2020
  77. Self-expandable metallic stenting as a bridge to surgery for malignant colorectal obstruction: pooled analysis of 426 patients from two prospective multicenter series., Surgical endoscopy, 33巻, 2号, 2019
  78. Factors related to difficult self-expandable metallic stent placement for malignant colonic obstruction: A post-hoc analysis of a multicenter study across Japan., Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 31巻, 1号, 2019
  79. Long-term prognosis after treatment for T1 carcinoma of laterally spreading tumors: a multicenter retrospective study., International journal of colorectal disease, 34巻, 3号, 2019
  80. Local recurrence of diminutive colorectal polyps after cold forceps polypectomy with jumbo forceps followed by magnified narrow-band imaging: a multicenter prospective study., Endoscopy, 51巻, 3号, 2019
  81. Case of a small intestinal arteriovenous malformation diagnosed by double-balloon enteroscopy preoperatively., Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 31巻, 3号, 2019
  82. First two cases of Zenker's diverticulum treated with flexible endoscopic septum division in Japan., Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 31巻, 3号, 2019
  83. Use of a colonic stent to recover a biliary stent retained by malignant colonic obstruction., Endoscopy, 51巻, 9号, 2019
  84. Preceding endoscopic submucosal dissection for T1 colorectal carcinoma does not affect the prognosis of patients who underwent additional surgery: a large multicenter propensity score-matched analysis., Journal of gastroenterology, 54巻, 10号, 2019
  85. Adenocarcinoma arising from heterotopic gastric mucosa in the postoperative stomach for 5 years., Gastrointestinal endoscopy, 90巻, 4号, 2019
  86. Usefulness and safety of colorectal precutting EMR and hybrid endoscopic submucosal dissection for sessile serrated polyps with use of a novel multifunctional snare., VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy, 4巻, 6号, 2019
  87. Submucosal Injection Solutions for ESD: Separating the Winners from the Losers., Digestive diseases and sciences, 64巻, 10号, 2019
  88. Endoscopic submucosal dissection of colorectal tumors using a novel monopolar scissor-type knife "SB Knife Jr.2"., Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 31巻, 6号, 2019
  89. Clinical outcomes of endoscopic submucosal dissection for colorectal tumors: a large multicenter retrospective study from the Hiroshima GI Endoscopy Research Group., Gastrointestinal endoscopy, 87巻, 3号, 2018
  90. Analysis of learning curves in gastroscopy training: the need for composite measures for defining competence., Gut, 67巻, 6号, 2018
  91. Feasibility and outcomes of underwater endoscopic mucosal resection for ≥ 10 mm colorectal polyps., Surgical endoscopy, 32巻, 6号, 2018
  92. Endoscopic submucosal dissection of early gastric neoplasms in the fornix using the newly developed scissor-type SB knife GX., Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 30巻, 1号, 2018
  93. A rare case of esophageal lymphoepithelial carcinoma without Epstein-Barr virus infection., Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 50巻, 4号, 2018
  94. Impact of endoscopic stent insertion on detection of viable circulating tumor cells from obstructive colorectal cancer., Oncology letters, 15巻, 1号, 2018
  95. New and emerging techniques for endoscopic treatment of Zenker's diverticulum: State-of-the-art review., Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 30巻, 4号, 2018
  96. Gastric and enteric anisakiasis successfully treated with Gastrografin therapy: A case report., World journal of gastrointestinal endoscopy, 10巻, 3号, 2018
  97. Endoscopic submucosal dissection for early esophageal neoplasms using the stag beetle knife., World journal of gastroenterology, 24巻, 15号, 2018
  98. Underwater EMR with submucosal lift for a small intestinal polyp in a patient with Peutz-Jeghers syndrome., VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy, 3巻, 4号, 2018
  99. Transformation of jejunoileal follicular lymphoma into diffuse large B-cell lymphoma detected using double-balloon enteroscopy., BMJ case reports, 2018巻, 2018
  100. Endoscopic full-thickness resection for inverted Meckel's diverticulum using double-balloon enteroscopy., Endoscopy, 49巻, S 01号, 2017
  101. Long-term outcomes after treatment for T1 colorectal carcinoma: a multicenter retrospective cohort study of Hiroshima GI Endoscopy Research Group., Journal of gastroenterology, 52巻, 11号, 2017
  102. [A case of ileus due to radiation enteritis 19 years after radiotherapy]., Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 114巻, 4号, 2017
  103. Endoscopic submucosal dissection of early colorectal neoplasms with a monopolar scissor-type knife: short- to long-term outcomes., Endoscopy, 49巻, 9号, 2017
  104. Replacement of warfarin with a novel oral anticoagulant in endoscopic mucosal resection: a multicentre, open-label, randomised controlled trial., BMJ open gastroenterology, 4巻, 1号, 2017
  105. Rectal polyp reaching the dentate line: underwater EMR without submucosal lift., VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy, 2巻, 3号, 2017
  106. Use of hemostatic powder in bleeding portal hypertensive gastropathy., VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy, 2巻, 9号, 2017
  107. Endoscopic submucosal dissection with a scissors-type knife for post-EMR recurrence tumor involving the colon diverticulum., VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy, 2巻, 8号, 2017
  108. Usefulness and safety of a scissors-type knife in endoscopic submucosal dissection for nonampullary duodenal epithelial tumors., VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy, 2巻, 10号, 2017
  109. Long-term outcomes after treatment for pedunculated-type T1 colorectal carcinoma: a multicenter retrospective cohort study., Journal of gastroenterology, 51巻, 7号, 2016
  110. A prospective multicenter study on self-expandable metallic stents as a bridge to surgery for malignant colorectal obstruction in Japan: efficacy and safety in 312 patients., Surgical endoscopy, 30巻, 9号, 2016
  111. Safety and efficacy of self-expandable metallic stents in malignant small bowel obstructions., World journal of gastroenterology, 22巻, 40号, 2016
  112. Clarithromycin Versus Metronidazole as First-line Helicobacter pylori Eradication: A Multicenter, Prospective, Randomized Controlled Study in Japan., Journal of clinical gastroenterology, 49巻, 6号, 2015
  113. Endoscopic submucosal dissection using a stag beetle knife for early esophageal cancer in lower esophageal diverticula., Gastrointestinal endoscopy, 82巻, 3号, 2015
  114. A Japanese prospective multicenter study of self-expandable metal stent placement for malignant colorectal obstruction: short-term safety and efficacy within 7 days of stent procedure in 513 cases., Gastrointestinal endoscopy, 82巻, 4号, 2015
  115. Dual therapy for third-line Helicobacter pylori eradication and urea breath test prediction., World journal of gastroenterology, 18巻, 21号, 2012
  116. [Acute tumor lysis syndrome in the setting of advanced gastric cancer]., Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 109巻, 8号, 2012
  117. Evaluation of individual risk in nonvariceal gastrointestinal bleeding patients with NSAID administration: a multicenter study in Japan., Digestion, 86巻, 3号, 2012
  118. [Mass-forming autoimmune pancreatitis caused after resection of an IgG4-related renal pelvic lesion]., Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 108巻, 10号, 2011
  119. Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors., The American journal of pathology, 172巻, 2号, 2008
  120. Targeting the EGFR, VEGFR, and PDGFR on colon cancer cells and stromal cells is required for therapy., Clinical & experimental metastasis, 25巻, 4号, 2008
  121. Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors., Neoplasia (New York, N.Y.), 10巻, 5号, 2008
  122. The previously undescribed ZKSCAN3 (ZNF306) is a novel "driver" of colorectal cancer progression., Cancer research, 68巻, 11号, 2008
  123. Vascular endothelial growth factor C stimulates progression of human gastric cancer via both autocrine and paracrine mechanisms., Clinical cancer research : an official journal of the American Association for Cancer Research, 14巻, 22号, 2008
  124. Zonal heterogeneity for gene expression in human pancreatic carcinoma., Cancer research, 67巻, 16号, 2007
  125. Stromal metalloproteinase-9 is essential to angiogenesis and progressive growth of orthotopic human pancreatic cancer in parabiont nude mice., Neoplasia (New York, N.Y.), 9巻, 11号, 2007
  126. Inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation on tumor-associated endothelial cells leads to treatment of orthotopic human colon cancer in nude mice., Neoplasia (New York, N.Y.), 9巻, 12号, 2007
  127. Expression of activated platelet-derived growth factor receptor in stromal cells of human colon carcinomas is associated with metastatic potential., International journal of cancer, 119巻, 11号, 2006
  128. Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma., The American journal of pathology, 169巻, 6号, 2006
  129. Experimental observation of the 1/3 magnetization plateau in the diamond-chain compound Cu3(CO3)2(OH)2., Physical review letters, 94巻, 22号, 2005
  130. Expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in early gastric carcinoma: correlation with clinicopathological parameters., Cancer letters, 226巻, 1号, 2005
  131. Expression of p53 protein in esophageal squamous cell carcinoma: relation to hypoxia-inducible factor-1alpha, angiogenesis and apoptosis., Pathobiology : journal of immunopathology, molecular and cellular biology, 72巻, 4号, 2005
  132. Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor receptor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model., Cancer research, 65巻, 22号, 2005
  133. Angiogenic switch occurs during the precancerous stage of human esophageal squamous cell carcinoma., Oncology reports, 11巻, 2号, 2004
  134. Expression of VEGF-C and VEGF-D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma., Cancer science, 95巻, 1号, 2004
  135. Mutation of the von Hippel-Lindau (VHL) gene in human colorectal carcinoma: association with cytoplasmic accumulation of hypoxia-inducible factor (HIF)-1alpha., Cancer science, 95巻, 2号, 2004
  136. Regulation of vascular endothelial growth factor (VEGF)-C and VEGF-D expression by the organ microenvironment in human colon carcinoma., European journal of cancer (Oxford, England : 1990), 40巻, 10号, 2004
  137. Expression of hypoxia-inducible factor (HIF)-1alpha is associated with vascular endothelial growth factor expression and tumour angiogenesis in human oesophageal squamous cell carcinoma., European journal of cancer (Oxford, England : 1990), 40巻, 12号, 2004
  138. Single nucleotide polymorphism in the hypoxia-inducible factor-1alpha gene in colorectal carcinoma., Oncology reports, 12巻, 5号, 2004
  139. The specific expression of hypoxia inducible factor-1alpha in human gastric mucosa induced by nonsteroidal anti-inflammatory drugs., Alimentary pharmacology & therapeutics, 18 Suppl 1巻, 2003
  140. Minute depressed colon cancer with submucosal invasion., Gastrointestinal endoscopy, 57巻, 4号, 2003
  141. Expression of hypoxia-inducible factor-1alpha is associated with tumor vascularization in human colorectal carcinoma., International journal of cancer, 105巻, 2号, 2003
  142. Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types., International journal of molecular medicine, 12巻, 4号, 2003
  143. [Treatment of colorectal carcinoma having submucosal invasion]., Nihon rinsho. Japanese journal of clinical medicine, 61 Suppl 7巻, 2003
  144. Determining depth of invasion by VN pit pattern analysis in submucosal colorectal carcinoma., Oncology reports, 9巻, 5号, 2002
  145. [A case of lymphangioma of the pancreas]., Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 96巻, 10号, 1999
  146. Management of T1 Colorectal Cancer., Digestion, 2024
  147. Vertical margin distance in T1 colorectal carcinoma resected by endoscopic submucosal dissection affects prognosis after additional surgery., International journal of colorectal disease, 39巻, 1号, 2024
  148. Correction to: Treatment Decision for Locally Resected T1 Colorectal Carcinoma-Verification of the Japanese Guideline Criteria for Additional Surgery Based on Long-Term Clinical Outcomes., The American journal of gastroenterology, 119巻, 11号, 2024
  149. Clinicopathologic Features of Early Gastric Cancer after Heli-cobacter pylori Eradication in Japanese Patients: Comparative Study between Early (<10 Years) and Late (>10 Years) Onset., Cancers, 16巻, 18号, 2024
  150. Urgent Contrast-Enhanced Computed Tomography before Early Colonoscopy in the Management of Colonic Diverticular Bleeding: A Multicenter Randomized Controlled Trial., Digestion, 2024
  151. Genetic Analysis of Biopsy Tissues from Colorectal Tumors in Patients with Ulcerative Colitis., Cancers, 16巻, 19号, 2024
  152. Solitary Colonic Ganglioneuroma With Central Depression: A Rare Case With Unique Morphology., The American journal of gastroenterology, 2024
  153. A case of esophageal squamous cell carcinoma with epidermization showing a unique morphology., Clinical journal of gastroenterology, 2024
  154. Response to Yu Yang et al., The American journal of gastroenterology, 120巻, 4号, 2025
  155. Helicobacter pylori-positive colorectal MALT lymphoma with repeated metachronous recurrence after a complete response to eradication therapy and regression after a watch-and-wait strategy., Internal medicine (Tokyo, Japan), 2025
  156. Endoscopic features differentiating non-Helicobacter pylori Helicobacter-induced gastric mucosa-associated lymphoid tissue lymphoma with a nodular gastritis-like appearance and H. pylori-induced conventional nodular gastritis., Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2025
  157. Long-term results of palliative placement of very low-axial force self-expandable metallic stents for malignant colorectal obstruction., DEN open, 6巻, 1号, 2026
  158. Prophylactic clip closure after endoscopic submucosal dissection of large flat and sessile colorectal polyps: a multicentre randomised controlled trial (EPOC trial)., Gut, 2025
  159. [Methotrexate-related lymphoproliferative disease of the ileum with fistular formation between the small bowel and rectum:a case report]., Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 122巻, 6号, 2025
  160. Clinical Significance of Small-Bowel Mucosal Changes in Liver Cirrhosis Patients With Suspected Small-Bowel Bleeding: A Capsule Endoscopy Study., Journal of gastroenterology and hepatology, 40巻, 7号, 2025
  161. Endoscopic drainage for the treatment of intramural colonic abscess., Endoscopy, 57巻, S 01号, 2025
  162. Lymph node metastasis and treatment outcomes of endoscopic submucosal dissection for superficial spreading esophageal squamous cell carcinoma ≥ 50 mm in size., Esophagus : official journal of the Japan Esophageal Society, 2025

著書等出版物

  1. 2012年, 見逃しのない大腸内視鏡の挿入・観察法 : ワンランク上を目指す初学者から中級者のために, 日本メディカルセンタ, 永田信二, 岡志郎編集, 9784888752480
  2. 2017年, 消化器内視鏡基本手技のすべて : 上級医を目指すキミへ, 南江, 花田敬士編集, 9784524259991
  3. 2020年, 大腸EMR・ESDの基本とコツ : エキスパートならではの治療手技・戦略を伝授, 羊土, 永田信二, 岡志郎編集, 9784758110709
  4. 2022年, 大腸腫瘍内視鏡治療の要点と盲点, 文光, 斎藤豊, 岡志郎編集, 9784830621147
  5. 2023年, 大腸ステントハンドブック, シービーアー, 大腸ステント安全手技研究会監修 ; 斉田芳久編集 ; 伊佐山浩通編集, 9784911108093
  6. 2023年, レジデントのための消化器内視鏡ことはじめ, メジカルビュー, 浦岡俊夫編集, 9784758315494

招待講演、口頭・ポスター発表等

  1. SAFETY AND EFFICACY OF A LOW AXIAL FORCE SELF-EXPANDABLE METALLIC STENT FOR MALIGNANT COLORECTAL OBSTRUCTION, DDW2025, 2025年05月04日, 通常, 英語
  2. 内視鏡治療におけるビスコクリアの活用法, 広島臨床消化管セミナー2025, 2025年05月13日, 招待, 日本語
  3. ハサミ型ナイフを用いた内視鏡治療, 第11回　京都広小路ライブセミナー, 2025年03月29日, 招待, 日本語
  4. 大腸ステントの基本から応用まで～Gel immersion Endoscopyを含めて～, 第４回　大阪内視鏡懇話会, 2025年03月21日, 招待, 日本語
  5. 大腸がん検診と質の高い大腸内視鏡検査の重要性, 第94回北陸支部生涯教育講演会, 2025年03月09日, 招待, 日本語
  6. 大腸内視鏡検査の基本と今後の展望, 広島市佐伯区医師会学術講演会, 2025年02月18日, 招待, 日本語
  7. Zenker憩室に対する内視鏡治療, 第12回九州セミナー, 2025年02月07日, 招待, 日本語
  8. 大腸悪性狭窄に対する内視鏡治療, 第171回備後内視鏡研究会, 2024年11月26日, 招待, 日本語
  9. 大腸内視鏡検査の基本と今後の展望, 第55回日本消化器がん検診学会中国四国地方会, 2024年11月09日, 通常, 日本語
  10. 内視鏡AI 診断の実際～gastroAI™ model-Gによる臨床報告～ 進化する内視鏡AI～gastroAI™ model-Gを使用して～, 第132回日本消化器内視鏡学会中国支部例会, 2024年07月14日, 通常, 日本語
  11. 中国地区における消化器内視鏡治療の最前線, 第132回日本消化器内視鏡学会中国支部例会, 2024年07月14日, 通常, 日本語
  12. 大腸ステントについて, 第120回安佐消化器病フォーラム, 2024年07月02日, 通常, 日本語
  13. 内視鏡による診断と治療の進歩, 第100回北海道腸疾患研究会, 2024年06月15日, 通常, 日本語
  14. 大腸ステントの基礎から最新エビデンス, 広島臨床消化管セミナー2024, 2024年05月14日, 通常, 日本語

受賞

  1. GIE, VideoGIE and iGIE Reviewer Award, 米国消化器内視鏡学会
  2. GIE, VideoGIE and iGIE Reviewer Award, 米国消化器内視鏡学会
  3. 最優秀ワークショップ部門賞, 第127回日本消化器内視鏡学会中国支部例会
  4. GIE and VideoGIE Reviewer Award, 米国消化器内視鏡学会
  5. GIE and VideoGIE Reviewer Award, 米国消化器内視鏡学会
  6. 国立病院機構優秀論文賞, 独立行政法人国立病院機構
  7. GIE and VideoGIE Reviewer Award, 米国消化器内視鏡学会
  8. Excellent reviewer of the month, VideoGIE
  9. Excellent reviewer of the month, VideoGIE
  10. Poster of Excellence, 欧州消化器病関連学会週間
  11. Poster of Excellence, 欧州消化器病関連学会週間
  12. AACR Scholar in Training Award, 米国癌学会

社会活動

その他社会貢献活動（広大・部局主催含）

  1. がんを知り、がんと向き合う市民公開講座, 大腸がんを早く見つけて内視鏡で治そう！, 2024年/02月/17日
  2. 大腸ステント治療に脚光, 中国新聞　朝刊　くらし面, 2022年/06月/22日
  3. おはようフォーカス：一年に一回の内視鏡でがん対策, RCCラジオ　おはようラジオ, 2021年/07月/13日
  4. おはようフォーカス：潰瘍性大腸炎とは, RCCラジオ　おはようラジオ, 2021年/05月/14日
  5. 咽頭食道憩室の内視鏡治療, 中国新聞　朝刊　くらし面, 2021年/03月/03日, その他
  6. プロフェッショナル-仕事の流儀-, 2019年/09月/10日, 出演, テレビ・ラジオ番組
  7. ブルーリボンキャラバン　市民公開講座　～もっと知ってほしい大腸がんのこと2017 in 呉, 大腸がんの見つけ方と内視鏡治療について, 2017年/07月/02日, その他
  8. 第7回呉医療センターメディカルフェスタ2014市民向け公開講座, 胃がんについて, 2014年/10月/04日, その他
  9. がんを知り、がんと向き合う市民公開講座, 胃がんの診断と最新治療, 2014年/03月/09日, その他