猪村 剛史TAKESHI IMURA

Last Updated :2025/04/14

所属・職名
大学院医系科学研究科（保）　准教授
メールアドレス
imuratkshhiroshima-u.ac.jp

基本情報

学位

  • 博士（保健学）　(広島大学)

研究活動

学術論文（★は代表的な論文）

  1. Skills training in activities of daily living for persons living with dementia: a scoping review protocol., BMJ open, 15巻, 4号, 2025
  2. Psychological Interventions to Improve Upper Limb Motor Dysfunction Post-stroke: A Scoping Review., Cureus, 17巻, 1号, 2025
  3. Bioinformatic Exploration of Circulating microRNAs Related to Functional Outcomes in Patients With Acute Ischemic Stroke: An Exploratory Prospective Study., Cureus, 16巻, 8号, 2024
  4. The effects of nonpharmacological sleep hygiene on sleep quality in nonelderly individuals: A systematic review and network meta-analysis of randomized controlled trials., PloS one, 19巻, 6号, 2024
  5. Identifying the characteristics of patients with stroke who have difficulty benefiting from gait training with the hybrid assistive limb: a retrospective cohort study., Frontiers in neurorobotics, 18巻, 2024
  6. Characteristics of MicroRNA Expression Depending on the Presence or Absence of Meningioma in Patients with Neurofibromatosis Type 2: A Secondary Analysis., Neurologia medico-chirurgica, 64巻, 3号, 2024
  7. Clinically significant effects of gait modification on knee pain: A systematic review and meta-analysis., Journal of back and musculoskeletal rehabilitation, 37巻, 1号, 2024
  8. Interventions to improve locomotive syndrome: a systematic review and meta-analysis of randomized controlled trials., Nagoya journal of medical science, 85巻, 2号, 2023
  9. Effects of age and gender on spatiotemporal and kinematic gait parameters in older adults., Acta of bioengineering and biomechanics, 24巻, 4号, 2022
  10. Cough sound-based estimation of vital capacity via cough peak flow using artificial neural network analysis., Scientific reports, 13巻, 1号, 2023
  11. A Simplified Clinical Prediction Rule for Prognosticating Dependent Daily Living in Patients with Thoracic Spinal Cord Injury: A Multicenter Nationwide Japan Registry Study., European neurology, 86巻, 3号, 2023
  12. Exploratory integrated analysis of circulating exosomal miRNA and tissue mRNA related to long-term physical activity for more than 25 years: a bioinformatics study., European journal of applied physiology, 123巻, 7号, 2023
  13. Early Initiation of Exoskeletal Robotic Gait Training Improves Functional Outcomes in the Patients with Stroke: A Retrospective Observational Study., European neurology, 86巻, 2号, 2023
  14. Effects of Non-Face-to-Face and Noncontact Interventions on Knee Pain and Physical Activity in Older Adults With Knee Osteoarthritis: A Systematic Review and Meta-Analysis., Journal of aging and physical activity, 31巻, 2号, 2023
  15. The effects of walking training with poles on walking ability: A systematic review and meta-analysis of randomized controlled trials., PM & R : the journal of injury, function, and rehabilitation, 15巻, 8号, 2023
  16. The effectiveness of group education in people over 50 years old with knee pain: A systematic review and meta-analysis of randomized control trials., Musculoskeletal science & practice, 62巻, 2022
  17. Predicting the prognosis of unilateral spatial neglect using magnetic resonance imaging in patients with stroke: A systematic review., Brain research, 1789巻, 2022
  18. Effects of gait training with the Hybrid Assistive Limb on gait ability in stroke patients: A systematic review of randomized controlled trials., Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 101巻, 2022
  19. Effects of combined exercise and psychological interventions on psychological factors in patients who underwent total knee arthroplasty: A systematic review of randomized controlled trials, International Journal of Gerontology, 202210
  20. Clinical Prediction Rule for Identifying the Stroke Patients who will Obtain Clinically Important Improvement of Upper Limb Motor Function by Robot-Assisted Upper Limb., Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 31巻, 7号, 2022
  21. Prediction of Independent Gait in Acute Stroke Patients with Hemiplegia Using the Ability for Basic Movement Scale II Score., European neurology, 83巻, 1号, 2020
  22. Effects of Exoskeletal Lower Limb Robot Training on the Activities of Daily Living in Stroke Patients: Retrospective Pre-Post Comparison Using Propensity Score Matched Analysis., Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 29巻, 10号, 2020
  23. Development and Validation of Machine Learning-Based Prediction for Dependence in the Activities of Daily Living after Stroke Inpatient Rehabilitation: A Decision-Tree Analysis., Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 29巻, 12号, 2020
  24. The Effects of Vestibular Rehabilitation on Gait Performance in Patients with Stroke: A Systematic Review of Randomized Controlled Trials., Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 29巻, 11号, 2020
  25. Clinical Features for Identifying the Possibility of Toileting Independence after Convalescent Inpatient Rehabilitation in Severe Stroke Patients: A Decision Tree Analysis Based on a Nationwide Japan Rehabilitation Database., Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 30巻, 2号, 2021
  26. Decision Tree Algorithm Identifies Stroke Patients Likely Discharge Home After Rehabilitation Using Functional and Environmental Predictors., Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 30巻, 4号, 2021
  27. Machine Learning Algorithm Identifies the Importance of Environmental Factors for Hospital Discharge to Home of Stroke Patients using Wheelchair after Discharge., Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 30巻, 8号, 2021
  28. A systematic review of the usefulness of magnetic resonance imaging in predicting the gait ability of stroke patients., Scientific reports, 11巻, 1号, 2021
  29. Comparison of Supervised Machine Learning Algorithms for Classifying of Home Discharge Possibility in Convalescent Stroke Patients: A Secondary Analysis., Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 30巻, 10号, 2021
  30. Development of a clinical prediction rule for patients with cervical spinal cord injury who have difficulty in obtaining independent living., The spine journal : official journal of the North American Spine Society, 22巻, 2号, 2022
  31. Effects of Combining Online Anodal Transcranial Direct Current Stimulation and Gait Training in Stroke Patients: A Systematic Review and Meta-Analysis., Frontiers in human neuroscience, 15巻, 2021
  32. Distinctive MicroRNA Profiles in Serum of Patients with Neurofibromatosis Type 2: A Bioinformatic Exploratory Study., World neurosurgery, 164巻, 2022
  33. Developing a Clinical Prediction Rule for Gait Independence at Discharge in Patients with Stroke: A Decision-Tree Algorithm Analysis., Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 31巻, 6号, 2022
  34. Does frequent use of an exoskeletal upper limb robot improve motor function in stroke patients?, Disability and rehabilitation, 45巻, 7号, 2023
  35. Involvement of the Rostromedial Prefrontal Cortex in Human-Robot Interaction: fNIRS Evidence From a Robot-Assisted Motor Task., Frontiers in neurorobotics, 16巻, 2022
  36. Early Transplantation of Human Cranial Bone-derived Mesenchymal Stem Cells Enhances Functional Recovery in Ischemic Stroke Model Rats, NEUROLOGIA MEDICO-CHIRURGICA, 60巻, 2号, pp. 83-93, 202002
    DOIを用いた論文検索結果へのリンク
  37. "Microgravity" as a unique and useful stem cell culture environment for cell-based therapy, REGENERATIVE THERAPY, 12巻, pp. 2-5, 20191215
    DOIを用いた論文検索結果へのリンク
  38. Simulated microgravity-cultured mesenchymal stem cells improve recovery following spinal cord ischemia in rats, STEM CELL RESEARCH, 41巻, 201912
    DOIを用いた論文検索結果へのリンク
  39. Simulated microgravity enhances CDDP-induced apoptosis signal via p53-independent mechanisms in cancer cells, PLOS ONE, 14巻, 7号, 20190719
    DOIを用いた論文検索結果へのリンク
  40. Combination of Exoskeletal Upper Limb Robot and Occupational Therapy Improve Activities of Daily Living Function in Acute Stroke Patients, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 201907
  41. Simulated Microgravity Culture Enhances the Neuroprotective Effects of Human Cranial Bone-Derived Mesenchymal Stem Cells in Traumatic Brain Injury, STEM CELLS AND DEVELOPMENT, 27巻, 18号, pp. 1287-1297, 201809
    DOIを用いた論文検索結果へのリンク
  42. Stem cell culture in microgravity and its application in cell-based therapy, Stem Cells Dev, 2018
  43. Rat cranial bone-derived mesenchymal stem cells promotes functional recovery in ischemic stroke model through neuroprotective effects, Stem Cells Dev, 2018
  44. Simulated microgravity attenuates myogenic differentiation via epigenetic regulations, NPJ Microgravity, 2018
  45. Mesenchymal Stem Cell-Based Therapy Improves Lower Limb Movement After Spinal Cord Ischemia in Rats, ANNALS OF THORACIC SURGERY, 105巻, 5号, pp. 1523-1530, 201805
    DOIを用いた論文検索結果へのリンク
  46. Analysis of scapular kinematics during active and passive arm elevation, J Phys Ther Sci, 28巻, pp. 1876-1882, 2016
  47. Effect of early and intensive rehabilitation in acute stroke patients: retrospective pre/post comparison in Japanese hospital, Disabil Rehabil, 14巻, pp. 1-4, 2017
  48. Neuromagnetic evaluation of a communication support system for hearing-impaired patients, NEUROREPORT, 28巻, 12号, pp. 712-719, 20170816
    DOIを用いた論文検索結果へのリンク
  49. Predictions of motor outcomes and activities of daily living function using diffusion tensor tractography in acute hemiparetic stroke patients, J Phys Ther Sci, 2015
  50. Interactive effects of cell therapy and rehabilitation realize the full potential of neurogenesis in brain injury model, NEUROSCIENCE LETTERS, 555巻, pp. 73-78, 2013
  51. Electrical stimulation accelerates neuromuscular junction formation through ADAM19/neuregulin/ErbB signaling in vitro, NEUROSCIENCE LETTERS, 545巻, pp. 29-34, 2013
  52. Electrical stimulation enhances neurogenin2 expression through beta-catenin signaling pathway of mouse bone marrow stromal cells and intensifies the effect of cell transplantation on brain injury, NEUROSCIENCE LETTERS, 533巻, pp. 71-76, 2013
  53. Regulation of hematopoietic stem cells using protein transduction domain-fused Polycomb, EXPERIMENTAL HEMATOLOGY, 40巻, 9号, pp. 751-760, 2012

招待講演、口頭・ポスター発表等

  1. Isolation of mesenchymal stem cells derived from human cranial bone marrow, 14th International Society for Stem Cell Research (ISSCR), 2016年06月22日, 通常, 英語
  2. Myoblast differentiation is controlled by gravity force, American Society for Gravitational and Space Research (ASGSR), 2016年10月26日, 通常, 英語
  3. The effects of simulated microgravity on neural differntiation of human cranial bone marrow-derived mesenchymal stem cells, 32nd American Society for Gravitational and Space Research (ASGSR), 通常, 英語
  4. Neuromagnetic evaluation of communicaton support system for hearing-impaired subjects, 14th Society for Brain Mapping and Therapeutics (SBMT), 2017年04月18日, 通常, 英語
  5. Simulated microgravity culture increases the neuroprotective potential of cranial bone derived mesenchymal stem cells in brain injury model, 15th International Society for Stem Cell Research (ISSCR), 2017年06月16日, 通常, 英語
  6. Cranial bone derived mesenchymal stem cells cultured in simulated microgravity have highly neuroprotective effect against stress induced NG108-15 cell death in vitro, 15th International Society for Stem Cell Research (ISSCR), 2017年06月16日, 通常, 英語
  7. Simulated microgravity culture increases the neuroprotective potential of mesenchymal stem cells, 33rd American Society for Gravitational and Space Research (ASGSR), 2017年10月27日, 通常, 英語
  8. Myogenic differentiation is accelerated by hypergravity culture through epigenetic regulations, 33rd American Society for Gravitational and Space Research (ASGSR), 2017年10月27日, 通常, 英語
  9. Interactive effects of cell therapy and rehabilitation in brain injury model, Takeshi Imura, TERMIS2018, 2018年09月07日, 招待, 英語

外部資金

競争的資金等の採択状況

  1. 一般社団法人 日本損害保険協会 交通事故医療研究助成　一般研究助成, 外傷性神経損傷者に対するコンピューター制御膝継手を活用した革新的歩行トレーニングの開発に資する多角的研究, 2024年, 2025年
  2. 一般社団法人 日本義肢装具学会 2024年度研究助成, コンピューター制御膝継手が歩行動作時の運動学的指標および筋シナジーに与える影響, 2024年, 2026年
  3. 日本学術振興会 科学研究費助成事業　基盤研究 (C), 患者由来iPS細胞を用いた孤発性神経線維腫症Ⅱ型の病態解明とmiRNA治療の開発, 2023年, 2025年
  4. 厚生労働科学研究費補助金, エビデンスに基づいたロコモティブシンドローム早期対策の実践に資する包括的研究, 2022年, 2024年
  5. 日本学術振興会 科学研究費助成事業　若手研究, 脳卒中後の機能回復に寄与するマイクロRNAの大規模探索と革新的予後予測への応用, 2020年, 2022年
  6. 日本学術振興会 科学研究費助成事業　若手研究 (B), 脊髄損傷への幹細胞治療とロボットを用いたリハビリテーションによる新規治療の開発, 2017年, 2019年
  7. 日本学術振興会 科学研究費助成事業　研究活動スタート支援, 中枢神経障害に対する幹細胞治療とロボットを使用したリハビリテーションの併用効果, 2015年, 2016年
  8. 公益社団法人 広島県理学療法士会　平成26年度学術研究助成, 装具連携システム開発に関わる研究－地域包括ケア到来に向け理学療法士としてできること, 2014年
  9. 公益社団法人 日本理学療法士協会 平成26年度理学療法にかかわる研究助成 (指定研究), 急性期脳卒中患者に対する早期かつ充実したリハビリテーションの介入効果に関する研究, 2014年