大久保 陽策YOSAKU OKUBO

Last Updated :2025/05/09

所属・職名
病院(医) 助教
メールアドレス
yokubohiroshima-u.ac.jp
自己紹介
循環器内科学、特に不整脈分野の研究をしています。電気生理学、カテーテルアブレーション、植え込み型デバイス治療が専門です。

基本情報

主な職歴

  • 2010年04月, 2012年03月, 県立広島病院, 初期臨床研修医
  • 2012年04月, 2014年03月, あかね会土谷総合病院, 医員
  • 2014年04月, 2017年03月, 尾道総合病院, 医員
  • 2021年04月01日, 2024年03月31日, 広島大学, 病院, 医科診療医
  • 2024年04月01日, 広島大学, 病院, 助教

学歴

  • 広島大学, 大学院医歯薬保健学研究科, 博士課程医歯薬学専攻医学専門プログラム, 日本, 2017年04月, 2021年03月
  • 広島大学, 医学部, 医学科, 日本, 2003年04月, 2010年03月

学位

  • 博士(医学) (広島大学)

教育担当

  • 【博士課程】 医系科学研究科 : 医歯薬学専攻 : 医学専門プログラム

研究分野

  • 医歯薬学 / 内科系臨床医学 / 循環器内科学

所属学会

研究活動

学術論文(★は代表的な論文)

  1. Clinical Features of Tachycardia-induced Cardiomyopathy in Patients with Atrial Fibrillation, INTERNAL MEDICINE, 63巻, 18号, pp. 2509-2517, 2024
  2. Decreased plasma cell-free mitochondrial DNA may be a new biomarker of tachycardia-induced cardiomyopathy in patients with atrial fibrillation, INTERNATIONAL JOURNAL OF CARDIOLOGY, 417巻, 20241215
  3. ★, Conduction velocity mapping in atrial fibrillation using omnipolar technology, Pacing Clin Electrophysiol, 47巻, 1号, pp. 19-27, 2024
  4. Omnipolar mapping technology used in a patient with Purkinje-related ventricular tachycardia, HeartRhythm Case Repots, 9巻, 6号, pp. 386-390, 2023
  5. Initial experience of novel over the wire type decapolar catheter for ventricular arrhythmias originating from left ventricular summit, J Interv Card Electrophysiol ., 66巻, 1号, pp. 117-124, 2023
  6. Retrograde carbon dioxide coronary sinus venography, Pacing Clin Electrophysiol ., 46巻, 1号, pp. 31-33, 2023
  7. Plasma MicroRNAs as noninvasive diagnostic biomarkers in patients with Brugada syndrome, Plos one, 17巻, 5号, pp. e0261390., 2022
  8. Isochronal late activation mapping of epicardial ventricular tachycardia in a patient with midventricular obstructive hypertrophic cardiomyopathy, HeartRhythm Case reports, 8巻, 5号, pp. 374-377, 2022
  9. ★, Clinical impact of left bundle branch area pacing in heart failure with preserved ejection fraction and mid-range ejection fraction, Pacing Clin Electrophysiol ., 45巻, 4号, pp. 499-508, 2022
  10. Association between left atrial appendage fibrosis and thrombus formation: A histological approach, Journal of Cardiovascular Electrohysiology, 33巻, 4号, pp. 677-687, 2022
  11. Conduction properties of the preferential pathway in a patient with idiopathic outflow ventricular arrhythmia, Indian Pacing Electrophysiol J, 22巻, 2号, pp. 94-98, 2022
  12. ★, Evaluation of the Feasibility and Efficacy of a Novel Device for Screening Silent Atrial Fibrillation (MYBEAT Trial), Circulation Journal, 86巻, 2号, pp. 182-188, 2022
  13. Use of a high-density mapping catheter for Purkinje-related ventricular tachycardia in a patient with a previous history of anterior myocardial infarction, HeartRhythm CaseReport, 7巻, 4号, pp. 232-236, 2021
  14. Porphyromonas gingivalis and left atrial appendage spontaneous echo contrast in atrial fibrillation ablation candidates, Heart and vessel, 36巻, 11号, pp. 1721-1729, 2021
  15. Thoracoscopic stand-alone appendectomy for atrial tachycardia originating from the left atrial appendage in a patient with severe left ventricular dysfunction, Journal of Cardiology Cases, 23巻, 1号, pp. 20-23, 2020
  16. ★, Increased Urinary Liver-Type Fatty Acid-Binding Protein Level Predicts Major Adverse Cardiovascular Events in Patients With Hypertension, American journal of hypertention, 33巻, 7号, pp. 604-609, 2020
  17. ★, Predicting atrial fibrillation using a combination of genetic risk score and clinical risk factors, HeartRhythm, 17巻, 5号, pp. 699-705, 2020
  18. Causes of very late stent thrombosis investigated using optical coherence tomography, Internal medicine, 53巻, 18号, pp. 2031-2039, 2014
  19. Validation of lactate level as a predictor of early mortality in acute decompensated heart failure patients who entered intensive care unit, Journal of Cardiology, 65巻, 2号, pp. 164-170, 2015
  20. Chromosome 4q25 Variant rs6817105 Bring Sinus Node Dysfunction and Left Atrial Enlargement, Scientific Reports, 8巻, 1号, pp. 14565, 2018
  21. Ser96Ala genetic variant of the human histidine-rich calcium-binding protein is a genetic predictor of recurrence after catheter ablation in patients with paroxysmal atrial fibrillation, Plos one, 14巻, 3号, pp. e0213208, 2019
  22. Periodontal Treatment During the Blanking Period Improves the Outcome of Atrial Fibrillation Ablation, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 13巻, 8号, 20240416
  23. Lead deformation of the stylet-driven lead in left bundle branch area pacing, HEART RHYTHM, 20巻, 5号, pp. 781-782, 202305
  24. Relationship Between Fibrosis , Endocardial Endothelial Damage, and Thrombosis of Left Atrial Appendage in Atrial Fibrillation, JACC-CLINICAL ELECTROPHYSIOLOGY, 9巻, 7号, pp. 1158-1168, 202307
  25. ★, Increased Urinary Liver-Type Fatty Acid-Binding Protein Level Predicts Worsening Renal Function in Patients With Acute Heart Failure, Journal of cardiac failure, 24巻, 8号, pp. 520-524, 2018

社会活動

学術雑誌論文査読歴

  1. Journal of Cardiology, その他
  2. Heart and vessel, その他
  3. Journal of Arrhythmia, その他