西淵 いくのIKUNO NISIBUCHI

Last Updated :2022/12/02

所属・職名
病院(医) 講師
メールアドレス
ikunohiroshima-u.ac.jp

基本情報

学位

  • 博士(医学) (広島大学)

教育活動

授業担当

  1. 2022年, 学部専門, セメスター(前期), 放射線生物学・放射線健康リスク科学
  2. 2022年, 学部専門, 通年, 全身性疾患制御学
  3. 2022年, 学部専門, 集中, 臨床実習I
  4. 2022年, 学部専門, 集中, 臨床実習II

研究活動

学術論文(★は代表的な論文)

  1. Development of a radiomics and machine learning model for predicting occult cervical lymph node metastasis in patients with tongue cancer, ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 134巻, 1号, pp. 93-101, 202207
  2. Clinical Outcomes of Esophagectomy and Chemoradiotherapy After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinoma, ANTICANCER RESEARCH, 42巻, 5号, pp. 2791-2795, 202205
  3. Temporal changes and risk factors for esophageal stenosis after salvage radiotherapy in superficial esophageal cancer following non-curative endoscopic submucosal dissection, RADIOTHERAPY AND ONCOLOGY, 166巻, pp. 65-70, 202201
  4. Investigating the displacement of radio-active sources during gold-198 grain brachytherapy for hospitalized oral cancer patients, JOURNAL OF CONTEMPORARY BRACHYTHERAPY, 14巻, 2号, pp. 115-122, 2022
  5. Functional image guided radiation therapy planning in volumetric modulated arc therapy for patients with malignant pleural mesothelioma, ADVANCES IN RADIATION ONCOLOGY, 2巻, 2号, pp. 183-191, 2017
  6. Combined Ventilation and Perfusion Imaging Correlates With the Dosimetric Parameters of Radiation Pneumonitis in Radiation Therapy Planning for Lung Cancer, INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 93巻, 4号, pp. 778-787, NOV 15 2015
  7. Reorganization of Damaged Chromatin by the Exchange of Histone Variant H2A.Z-2., Int J Radiat Oncol Biol Phys, 89巻, 4号, pp. 736-744, 2014 Jul 15
  8. Time-Adjusted Internal Target Volume: A Novel Approach Focusing on Heterogeneity of Tumor Motion Based on 4-Dimensional Computed Tomography Imaging for Radiation Therapy Planning of Lung Cancer., INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 89巻, 5号, pp. 1129-1137, 2014 Aug 1
  9. Long-term results of definitive concurrent chemoradiotherapy for patients with esophageal submucosal cancer (T1bN0M0), INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 20巻, 5号, pp. 897-904, 2015, 10
  10. Relationship between sentinel lymph nodes and postoperative tangential fields in early breast cancer, evaluated using SPECT/CT, JOURNAL OF RADIATION RESEARCH, 56巻, 5号, pp. 835-840, SEP 2015
  11. The Time Course of Dynamic Computed Tomographic Appearance of Radiation Injury to the Cirrhotic Liver Following Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma, PLOS ONE, 10巻, 6号, 2015 JUN 11
  12. Stereotactic body radiotherapy for patients with small hepatocellular carcinoma ineligible for resection or ablation therapies, HEPATOLOGY RESEARCH, 45巻, 4号, pp. 378-386, 2015 APR
  13. Permeability Surface Area Product Using Perfusion Computed Tomography Is a Valuable Prognostic Factor in Glioblastomas Treated with Radiotherapy Plus Concomitant and Adjuvant Temozolomide, WORLD NEUROSURGERY, 97巻, pp. 21-26, JAN 2017
  14. Development of cystic malacia after high-dose cranial irradiation of pediatric CNS tumors in long-term follow-up, CHILDS NERVOUS SYSTEM, 33巻, 6号, pp. 957-964, JUN 2017
  15. Functional image guided radiation therapy planning in volumetric modulated arc therapy for patients with malignant pleural mesothelioma., Adv Radiat Oncol., 2巻, 2号, pp. 183-191, 2017/1/11
  16. Clinical outcomes of concurrent chemoradiotherapy with volumetric modulated arc therapy in patients with locally advanced nasopharyngeal carcinoma., Jpn J Radiol., 2017/9/8
  17. Clinical outcomes of concurrent chemoradiotherapy with volumetric modulated arc therapy in patients with locally advanced nasopharyngeal carcinoma, JAPANESE JOURNAL OF RADIOLOGY, 35巻, 11号, pp. 673-680, NOV 2017
  18. Evaluation of Prognostic Factors for Esophageal Squamous Cell Carcinoma Treated with Neoadjuvant Chemoradiotherapy Followed by Surgery, WORLD JOURNAL OF SURGERY, 42巻, 5号, pp. 1496-1505, MAY 2018
  19. Quantifying esophageal motion during free-breathing and breath-hold using fiducial markers in patients with early-stage esophageal cancer, PLOS ONE, 13巻, 6号, JUN 11 2018
  20. Preoperative prediction of a pathologic complete response of esophageal squamous cell carcinoma to neoadjuvant chemoradiotherapy, SURGERY, 164巻, 1号, pp. 40-48, JUL 2018
  21. Long-term outcome of stereotactic body radiotherapy for patients with small hepatocellular carcinoma, HEPATOLOGY RESEARCH, 48巻, 9号, pp. 701-707, AUG 2018
  22. Comparison of Stereotactic Body Radiation Therapy Combined With or Without Transcatheter Arterial Chemoembolization for Patients With Small Hepatocellular Carcinoma Ineligible for Resection or Ablation Therapies, TECHNOLOGY IN CANCER RESEARCH & TREATMENT, 17巻, JUL 1 2018
  23. Evaluation of optimization workflow using design of experiment (DoE) for various field configurations in volumetric-modulated arc therapy, PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 54巻, pp. 34-41, 201810
  24. Long-term results of neoadjuvant chemoradiotherapy using cisplatin and 5-fluorouracil followed by esophagectomy for resectable, locally advanced esophageal squamous cell carcinoma, JOURNAL OF RADIATION RESEARCH, 59巻, 5号, pp. 616-624, 201809
  25. Development of geometrically ideal dose distribution as a reference for treatment planning in VMAT using filtered back-projection method, PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 57巻, pp. 115-122, 201901
  26. Early Recurrence and Cancer Death After Trimodal Therapy for Esophageal Squamous Cell Carcinoma, ANTICANCER RESEARCH, 39巻, 3号, pp. 1433-1440, 201903
  27. Concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of the cervix in a uterus didelphys with vaginal septum, JOURNAL OF CONTEMPORARY BRACHYTHERAPY, 11巻, 2号, pp. 180-188, 2019
  28. Clinical Significance of F-18-Fluorodeoxyglucose-Positron Emission Tomography-Positive Lymph Nodes to Outcomes of Trimodal Therapy for Esophageal Squamous Cell Carcinoma, ANNALS OF SURGICAL ONCOLOGY, 26巻, 6号, pp. 1869-1878, 201906
  29. 化学療法が発症に関与したと思われる放射線筋炎の2例, 癌と化学療法, 45巻, 6号, pp. 1005-1007
  30. T1-3NOMO前立腺癌に対する強度変調放射線治療の中期治療成績, 広島医学, 71巻, 10号, pp. 663-668
  31. Comparison of clinical outcome between computed tomography-based image-guided brachytherapy and two-dimensional-based brachytherapy for cervical cancer, GYNECOLOGIC ONCOLOGY REPORTS, 29巻, pp. 79-82, 201908
  32. An overview of stereotactic body radiation therapy for hepatocellular carcinoma, EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 14巻, 4号, pp. 271-279, 20200402
  33. Effect of bevacizumab against cystic components of brain tumors, CANCER MEDICINE, 8巻, 15号, pp. 6519-6527, 201911
  34. Analysis of cardiac toxicity after definitive chemoradiotherapy for esophageal cancer using a biological dose-volume histogram, JOURNAL OF RADIATION RESEARCH, 61巻, 2号, pp. 298-306, 202003
  35. Effectiveness of salvage radiotherapy for superficial esophageal Cancer after non-curative endoscopic resection, RADIATION ONCOLOGY, 15巻, 1号, 20200601
  36. A Single Institution's Experience of Definitive Radiotherapy Using Volumetric-modulated Arc Therapy for Hypopharyngeal Cancers, ANTICANCER RESEARCH, 40巻, 7号, pp. 4183-4190, 202007
  37. Predictions of Pathological Features and Recurrence Based on FDG-PET Findings of Esophageal Squamous Cell Carcinoma after Trimodal Therapy, ANNALS OF SURGICAL ONCOLOGY, 27巻, 11号, pp. 4422-4430, 202010
  38. Long-term outcomes of induction chemotherapy followed by chemoradiotherapy using volumetric-modulated arc therapy as an organ preservation approach in patients with stage IVA-B oropharyngeal or hypopharyngeal cancers, JOURNAL OF RADIATION RESEARCH, 61巻, 4号, pp. 554-562, 202007
  39. Evaluation of optimization workflow using custom-made planning through predicted dose distribution for head and neck tumor treatment, PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 80巻, pp. 167-174, 202012
  40. Long-term results of definitive chemoradiotherapy for unresectable locally advanced esophageal squamous cell carcinoma, JOURNAL OF RADIATION RESEARCH, 62巻, 1号, pp. 142-148, 202101
  41. Distribution of Lymph Node Metastasis in Esophageal Squamous Cell Carcinoma After Trimodal Therapy, ANNALS OF SURGICAL ONCOLOGY, 28巻, 3号, pp. 1798-1807, 202103
  42. T2-FLAIR Mismatch Sign and Response to Radiotherapy in Diffuse Intrinsic Pontine Glioma, PEDIATRIC NEUROSURGERY, 56巻, 1号, pp. 1-9, 202103
  43. Evaluating Individual Radiosensitivity for the Prediction of Acute Toxicities of Chemoradiotherapy in Esophageal Cancer Patients, RADIATION RESEARCH, 195巻, 3号, pp. 244-252, 202103
  44. Efficacy and tolerability of preoperative chemoradiotherapy with S-1 alone for locally advanced rectal cancer, JOURNAL OF RADIATION RESEARCH, 62巻, 2号, pp. 300-308, 202103
  45. Predicting the Local Response of Esophageal Squamous Cell Carcinoma to Neoadjuvant Chemoradiotherapy by Radiomics with a Machine Learning Method Using F-18-FDG PET Images, DIAGNOSTICS, 11巻, 6号, 202106
  46. Treatment outcomes of real-time intraoral sonography-guided implantation technique of Au-198 grain brachytherapy for T1 and T2 tongue cancer, JOURNAL OF RADIATION RESEARCH, 62巻, 5号, pp. 871-876, 202109
  47. Brachytherapy with Au-198 grains for cancer of the floor of the mouth: relationships between radiation dose and complications, ORAL RADIOLOGY, 38巻, 1号, pp. 105-113, 202201
  48. Reirradiation Using Au-198 Grain Brachytherapy for Recurrent Oral Cancer Cases Previously Treated by Definitive Radiotherapy, ANTICANCER RESEARCH, 42巻, 1号, pp. 293-300, 202201
  49. Potential benefits of volumetric modulated arc therapy to reduce the incidence of >= grade 2 radiation pneumonitis in radiotherapy for locally advanced non-small cell lung cancer patients, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 51巻, 12号, pp. 1729-1735, 202112

著書等出版物

  1. 脳神経外科ジャーナル, 膠芽腫に対する補助療法の現状と新規治療法の可能性, 2020年, 3, その他, 共著, 山崎 文之, 西淵 いくの
  2. 臨床画像 特集:画像診断医にも知ってほしい放射線治療:画像が担う役割, [画像情報の利用:治療計画立案からフォローアップまで] 食道癌, 2020年, 2, その他, 単著, 西淵 いくの

招待講演、口頭・ポスター発表等

  1. MRIを用いたradiomics解析による子宮頸癌傍大動脈リンパ節転移予測モデルの構築, 西淵 いくの,, 河原 大輔, 河村 征志, 三好 章太, 久保 克麿, 勝田 剛, 今野 伸樹, 竹内 有樹, 齋藤 明登, 村上 祐司, 永田 靖, 日本放射線腫瘍学会第34回学術大会, 2021年11月, 通常, 日本語
  2. A prediction model for para-aortic lymph node metastasis in cervical cancer by radiomics analysis using pre-treatment MRI images of the primary tumor., Nishibuchi I, Kawahara d, Kawamura M, Kubo K, Imano N, Takeuchi Y, Saito A, Murakami Y, Nagata Y, ASTRO 2021(American Society for Therapeutic Radiology and Oncology 63rd the Annual Meeting), 2021年10月, 通常, 英語
  3. 切除可能局所進行食道癌に対する予防領域照射を用いた根治的化学放射線療法の長期成績, 西淵 いくの, 村上 祐司、亀岡 翼、越智 雅則、今野 伸樹、竹内 有樹、高橋 一平、木村 智樹、永田 靖, 第74回日本食道学会学術集会, 2020年12月, 通常, 日本語
  4. Temporal change and risk factor of esophageal stenosis after salvage radiotherapy for superficial esophageal cancer with non-curative endoscopic submucosal dissection, Nishibuchi I, Murakami Y, Kameoka T, Ochi M, Imano N, Takeuchi Y, Takahashi I, Kimura T, Nagata Y, ASTRO 2020 (American Society for Therapeutic Radiology and Oncology 62nd the Annual Meeting), 2020年10月, 通常, 英語
  5. 高齢者に対する食道癌根治的放射線療法の治療方針とG8スコアの関連, 西淵 いくの, 村上 祐司, 石原 聡一郎, 植田 太朗, 樺山 翔平, 久保 克麿, 今野 伸樹, 竹内 有樹, 木村 智樹, 永田 靖, 日本放射線腫瘍学会第33回学術大会, 2020年10月, 通常, 日本語
  6. Long-term outcome of definitive chemoradiotherapy for resectable locally advanced esophageal cancer, Nishibuchi I, Murakami Y, Kameoka T, Ochi M, Imano N, Takeuchi Y, Takahashi I, Kimura T, Nagata Y, "European Society for Radiotherapy and Oncology meets Asia 2019 (ESTRO) ", 2019年12月, 通常, 英語
  7. 内視鏡非治癒切除後食道癌に対する放射線療法後の食道狭窄についての検討, 西淵 いくの, 村上 祐司, 亀岡 翼, 越智 雅則, 今野 伸樹, 竹内 有樹, 高橋 一平, 木村 智樹, 永田 靖, 日本放射線腫瘍学会第32回学術大会, 2019年11月, 通常, 日本語
  8. Long-term results of definitive chemoradiotherapy with elective nodal irradiation using modern radiotherapy technique for resectable locally advanced esophageal cancer., Nishibuchi I, Murakami Y, Adachi Y, Imano N, Takeuchi Y, Takahashi I, Kimura T, Nagata Y, ASTRO 2019 (American Society for Therapeutic Radiology and Oncology 61st the Annual Meeting), 2019年09月, 通常, 英語
  9. Time-Adjusted Internal Target Volume (TTV) based on Four-Dimensional Computed Tomography (4D-CT) for Radiotherapy Planning of Lung Cancer, 西淵いくの, 米国放射線腫瘍学会, 2010年, 通常, 英語
  10. The Dynamics of Histone Variant H2A.Z upon DNA Damage., Ikuno Nishibuchi, 米国放射線腫瘍学会, 2011年, 通常, 英語
  11. Reorganization of Damaged Chromatin by the Exchange of Histone Variant H2A.Z-2., 西淵いくの, 米国放射線腫瘍学会, 2012年, 通常, 英語
  12. SUMO E3-Ligase Regulates DNA Damage-Dependent Exchange of the Histone Variant H2A.Z-2., 西淵いくの, 米国放射線腫瘍学会, 2013年, 通常, 英語
  13. Tolerability and Outcome of Definitive Chemoradiation Therapy for Elderly Patients With Esophageal Cancer., 西淵いくの, 米国放射線腫瘍学会, 2014年, 通常, 英語
  14. Relationship Between Sentinel Lymph Nodes and Postoperative Tangential Fields in Early Breast Cancer Evaluated by Using SPECT/CT, 2015年10月, 通常, 英語
  15. A Quantitative Index for Phase Selection in Planning of Respiratory Gating Radiation Therapy for Lung Cancer, 2015年10月, 通常, 英語
  16. Treatment results of high-dose methotrexate followed by whole brain radiotherapy with or without boost irradiation for primary CNS lymphoma., 西淵いくの, 日本放射線腫瘍学会, 2015年11月, 通常, 英語
  17. Current status and future strategy of radiotherapy for lung cancer., 永田靖, 日本放射線腫瘍学会, 2015年11月, 通常, 日本語
  18. Dosimetric comparison between volumetric modulated arc therapy and conventional 3D conformal radiotherapy for middle thoracic esophageal cancer., 土井歓子, 日本放射線腫瘍学会, 2015年11月, 通常, 日本語
  19. Interstitial brachytherapy for early stage tongue caner: An analysis of prognostic factor of regional metastasis and local recurrence., 竹内有樹, 日本放射線腫瘍学会, 2015年11月, 通常, 日本語
  20. Clinical features of metachronous cancer in patients with esophageal cancer treated by definitive radiation therapy., 村上祐司, 日本放射線腫瘍学会, 2015年11月, 通常, 日本語
  21. 全乳房照射期間中の乳房形態変化に影響を及ぼす因子について, 西淵いくの, 和田崎晃一, 永田 靖, 第66回中国・四国放射線治療懇話会, 2015年06月, 通常, 日本語
  22. 鎖骨上窩および傍胸骨領域を含めた乳房温存術後照射における強度変調回転照射(VMAT), 土井歓子, 木村智樹, 河野理香, 大西圭一, 川畑秀雄, 竹内有樹, 西淵いくの, 岡部智行, 斉藤明登, 権丈雅浩, 村上祐司, 小澤修一, 西尾禎治, 永田 靖, 金 隆史, 第124回日本医学放射線学会中国・四国地方会, 2015年06月, 通常, 日本語
  23. 前立腺癌前立腺全摘出術後の放射線治療成績, 竹内有樹, 村上祐司, 大西圭一, 西淵いくの, 岡部智行, 木村智樹, 永田 靖, 第125回日本医学放射線学会中国・四国地方会, 2015年12月, 通常, 日本語
  24. The incidence and location of seed migration after transperineal interstitial prostate brachytherapy with I-125 loose seeds, 西淵いくの, 和田崎晃一, 日本医学放射線学会総会, 2015年04月, 通常, 英語
  25. Salvage radiotherapy for superficial esophageal cancer after incomplete endoscopic resection, 西淵いくの, 米国放射線腫瘍学会, 2016年09月, 通常, 英語

受賞

  1. 2012年10月29日, ASTRO 54th annual meeting Resident Poster Viewing Recognition Award, 米国放射線腫瘍学会, Reorganization of Damaged Chromatin by the Exchange of Histone Variant H2A.Z-2
  2. 2015年11月20日, 梅垣賞, 日本放射線腫瘍学会, Reorganization of Damaged Chromatin by the Exchange of Histone Variant H2A.Z-2.

外部資金

競争的資金等の採択状況

  1. 科学研究費助成事業, 食道癌放射線療法における放射線感受性を加味した正常臓器耐容線量評価法の開発, 2017年, 2021年

社会活動

委員会等委員歴

  1. 広島がん高精度放射線治療センター運営協議会臓器別検討会議委員, 2017年10月, 2018年03月, 広島県
  2. 広島がん高精度放射線治療センター運営協議会臓器別検討会議委員, 2020年01月, 2020年03月, 広島県
  3. 広島医学会総会準備委員会委員, 2021年06月, 2022年03月, 広島県医師会

その他社会貢献活動(広大・部局主催含)

  1. 県民公開セミナー「ここまで来た!がん放射線治療」, 食道癌, 広島県地域保健対策協議会, 2017年/02月/12日, 2017年/02月/12日, 広島県医師会ホール, 講師, セミナー・ワークショップ, 社会人・一般
  2. 広島がん高精度放射線センター県民公開セミナー  その選択は正しいですか?今知っておきたい放射線治療, ~食道がん・頭頸部がん~, 広島県、広島市、広島県医師会, 2018年/02月/25日, 広島県医師会ホール, 講師, セミナー・ワークショップ, 社会人・一般