向田 圭子KEIKO MUKAIDA

Last Updated :2023/11/01

所属・職名
病院（医）　寄附講座教授
メールアドレス
kmkm0543hiroshima-u.ac.jp

基本情報

学位

  • 博士（医学）　(広島大学)

研究活動

学術論文（★は代表的な論文）

  1. The effects of dantrolene in the presence or absence of ryanodine receptor type 1 variants in individuals predisposed to malignant hyperthermia., Anaesthesia and intensive care, 50巻, 4号, 2022
  2. Age-Specific Clinical Features of Pediatric Malignant Hyperthermia: A Review of 187 Cases Over 60 Years in Japan, ANESTHESIA AND ANALGESIA, 135巻, 1号, pp. 128-135, 2022
  3. Myotoxicity of local anesthetics is equivalent in individuals with and without predisposition to malignant hyperthermia., Journal of anesthesia, 32巻, 4号, 2018
  4. Calcium channel blockers are inadequate for malignant hyperthermia crisis., Journal of anesthesia, 26巻, 4号, 2012
  5. Fulminant-type malignant hyperthermia in Japan: cumulative analysis of 383 cases., Journal of anesthesia, 21巻, 2号, 2007
  6. Functional analysis of ryanodine receptor type 1 p.R2508C mutation in exon 47., Journal of anesthesia, 23巻, 3号, 2009
  7. Mutated p.4894 RyR1 function related to malignant hyperthermia and congenital neuromuscular disease with uniform type 1 fiber (CNMDU1)., Anesthesia and analgesia, 113巻, 6号, 2011
  8. Several Ryanodine Receptor Type 1 Gene Mutations of p.Arg2508 Are Potential Sources of Malignant Hyperthermia., Anesthesia and analgesia, 121巻, 4号, 2015
  9. Genetic and functional analysis of the RYR1 mutation p.Thr84Met revealed a susceptibility to malignant hyperthermia., Journal of anesthesia, 32巻, 2号, 2018
  10. Several Ryanodine Receptor Type 1 Gene Mutations of p.Arg2508 Are Potential Sources of Malignant Hyperthermia, ANESTHESIA AND ANALGESIA, 121巻, 4号, pp. 994-1000, 2015
  11. Functional analysis of newly identified RYR1 variants in patients susceptible to malignant hyperthermia., Journal of anesthesia, 34巻, 5号, 2020
  12. Effects of Remimazolam and Propofol on Ca2+ Regulation by Ryanodine Receptor 1 with Malignant Hyperthermia Mutation., BioMed research international, 2021巻, 2021
  13. Genetic and functional analysis of the RYR1 mutation p.Thr84Met revealed a susceptibility to malignant hyperthermia, JOURNAL OF ANESTHESIA, 32巻, 2号, pp. 174-181, 2018
  14. Malignant hyperthermia in a 16-day-old infant with congenital diaphragmatic hernia: a case report., Journal of anesthesia, 35巻, 2号, 2021
  15. Malignant hyperthermia susceptibility diagnosed with a family-specific ryanodine receptor gene type 1 mutation., Journal of anesthesia, 22巻, 1号, 2008
  16. [Malignant hyperthermia during emergency craniotomy: a case report]., Masui. The Japanese journal of anesthesiology, 52巻, 7号, 2003
  17. [Malignant hyperthermia]., Nihon rinsho. Japanese journal of clinical medicine, 60 Suppl 1巻, 2002
  18. Rapid Dantrolene Administration with Body Temperature Monitoring Is Associated with Decreased Mortality in Japanese Malignant Hyperthermia Events., BioMed research international, 2023巻, 2023
  19. Two different variants of p.2508 in Japanese malignant hyperthermia patients causing hypersensitivity of ryanodine receptor 1, EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 31巻, pp. 123-123, 2014
  20. Effects of propofol on calcium homeostasis in human skeletal muscle, ANAESTHESIA AND INTENSIVE CARE, 37巻, 3号, pp. 415-425, 2009
  21. Functional analysis of ryanodine receptor type 1 p.R2508C mutation in exon 47, JOURNAL OF ANESTHESIA, 23巻, 3号, pp. 341-346, 2009
  22. Analysis of human cultured myotubes responses mediated by ryanodine receptor 1, ANAESTHESIA AND INTENSIVE CARE, 39巻, 2号, pp. 252-261, 2011
  23. Mutated p.4894 RyR1 Function Related to Malignant Hyperthermia and Congenital Neuromuscular Disease with Uniform Type 1 Fiber (CNMDU1), ANESTHESIA AND ANALGESIA, 113巻, 6号, pp. 1461-1467, 2011
  24. The severity of sevoflurane-induced malignant hyperthermia, ACTA ANAESTHESIOLOGICA SCANDINAVICA, 56巻, 3号, pp. 351-356, 2012
  25. Prediction of accelerated Ca-induced Ca release rate by clinical findings in malignant hyperthermia susceptible subjects, IN VIVO, 15巻, 1号, pp. 45-48, 2001
  26. Susceptibility to malignant hyperthermia manifested as delayed return of increased serum creatine kinase activity and episodic rhabdomyolysis after exercise, ANESTHESIOLOGY, 87巻, 6号, pp. 1565-1567, 1997
  27. MALIGNANT HYPERTHERMIA DURING SEVOFLURANE ANESTHESIA IN A CHILD WITH CENTRAL CORE DISEASE, ANESTHESIOLOGY, 75巻, 4号, pp. 699-701, 1991
  28. BIOTRANSFORMATION OF ISOFLURANE - URINARY AND SERUM FLUORIDE-ION AND ORGANIC FLUORINE, ANESTHESIOLOGY, 69巻, 2号, pp. 218-222, 1988