山路 貴之TAKAYUKI YAMAJI

Last Updated :2024/05/08

所属・職名
広島大学　研究員

基本情報

学位

  • 博士　(広島大学)

研究キーワード

  • 家族性高コレステロール血症
  • 動脈硬化

研究活動

学術論文（★は代表的な論文）

  1. Association of cumulative low-density lipoprotein cholesterol exposure with vascular function., Journal of clinical lipidology, 20231225
  2. Impact of overnight 1 mg dexamethasone on vascular function in patients with nonfunctioning adrenal adenomas., Scientific reports, 13巻, 1号, pp. 20975-20975, 20231128
  3. Seasonal variations in endothelium-dependent flow-mediated vasodilation and endothelium-independent nitroglycerine-induced vasodilation., Hypertension research : official journal of the Japanese Society of Hypertension, 20231115
  4. Role of Small Dense Low-density Lipoprotein Cholesterol in Cardiovascular Events in Patients with Coronary Artery Disease and Type 2 Diabetes Mellitus Receiving Statin Treatment., Journal of atherosclerosis and thrombosis, 20231103
  5. Percentage of mean arterial pressure as a marker of atherosclerosis for detecting patients with coronary artery disease., Hypertension research : official journal of the Japanese Society of Hypertension, 20231004
  6. KCNJ5 mutation is a predictor for recovery of endothelial function after adrenalectomy in patients with aldosterone-producing adenoma., Hypertension research : official journal of the Japanese Society of Hypertension, 46巻, 9号, pp. 2213-2227, 202309
  7. Endothelial Function Is Preserved in Patients with Wild-Type Transthyretin Amyloid Cardiomyopathy., Journal of clinical medicine, 12巻, 7号, 20230327
  8. 当院における家族性高コレステロール血症早期発見のための取り組みについて, 広島医学, 202302
  9. Effect of exposure to radiation caused by an atomic bomb on endothelial function in atomic bomb survivors., Frontiers in cardiovascular medicine, 10巻, pp. 1122794-1122794, 2023
  10. Serum Potassium Levels of 4.5 to Less Than 5.0 mmol/L Are Associated with Better Vascular Function., Journal of atherosclerosis and thrombosis, 29巻, 11号, pp. 1588-1602, 20221101
  11. The prevalence of cardiovascular disease is higher in patients with bilateral low ankle-brachial index than in patients with unilateral low ankle-brachial index., Atherosclerosis, 360巻, pp. 8-14, 202211
  12. Relationship of Daily Coffee Intake with Vascular Function in Patients with Hypertension., Nutrients, 14巻, 13号, 20220629
  13. White blood cell count is not associated with flow-mediated vasodilation or nitroglycerine-induced vasodilation., Scientific reports, 12巻, 1号, pp. 8201-8201, 20220517
  14. Self-reported total sitting time on a non-working day is associated with blunted flow-mediated vasodilation and blunted nitroglycerine-induced vasodilation., Scientific reports, 12巻, 1号, pp. 6366-6366, 20220416
  15. Isolated diastolic hypertension is not associated with endothelial dysfunction., Hypertension research : official journal of the Japanese Society of Hypertension, 45巻, 4号, pp. 698-707, 202204
  16. Relationship between hemoglobin A1c level and flow-mediated vasodilation in patients with type 2 diabetes mellitus receiving antidiabetic drugs., Journal of diabetes investigation, 13巻, 4号, pp. 677-686, 202204
  17. Short stature is associated with low flow-mediated vasodilation in Japanese men., Hypertension research : official journal of the Japanese Society of Hypertension, 45巻, 2号, pp. 308-314, 202202
  18. Vascular Dysfunction Predicts Future Deterioration of Left Ventricular Ejection Fraction in Patients with Heart Failure with Mildly Reduced Ejection Fraction., Journal of clinical medicine, 10巻, 24号, 20211220
  19. Upstroke time as a marker of atherosclerosis in patients with diabetes mellitus who have a normal ankle-brachial index., Journal of diabetes and its complications, 35巻, 11号, pp. 108044-108044, 202111
  20. Stair climbing activity and vascular function in patients with hypertension., Hypertension research : official journal of the Japanese Society of Hypertension, 44巻, 10号, pp. 1274-1282, 202110
  21. A body shape index is associated with endothelial dysfunction in both men and women., Scientific reports, 11巻, 1号, pp. 17873-17873, 20210909
  22. Volume Elastic Modulus, Vascular Function, and Vascular Structure in Patients with Cardiovascular Risk Factors., Journal of atherosclerosis and thrombosis, 28巻, 9号, pp. 963-973, 20210901
  23. Inconvenient relationship of haemoglobin A1c level with endothelial function in type 2 diabetes in a cross-sectional study., BMJ open, 11巻, 6号, pp. e045415, 20210609
  24. Association of Body Mass Index with Endothelial Function in Asian Men., International journal of cardiology, 324巻, pp. 186-192, 20210201
  25. Smoking status and endothelial function in Japanese men., Scientific reports, 11巻, 1号, pp. 95-95, 20210108
  26. Lower triglyceride levels are associated with better endothelial function., Journal of clinical lipidology, 15巻, 3号, pp. 500-511, 2021
  27. Low-intensity pulsed ultrasound decreases major amputation in patients with critical limb ischemia: 5-year follow-up study., PloS one, 16巻, 8号, pp. e0256504, 2021
  28. Upstroke Time Is a Useful Vascular Marker for Detecting Patients With Coronary Artery Disease Among Subjects With Normal Ankle-Brachial Index., Journal of the American Heart Association, 9巻, 23号, pp. e017139, 202012
  29. Low Levels of Low-Density Lipoprotein Cholesterol and Endothelial Function in Subjects without Lipid-Lowering Therapy., Journal of clinical medicine, 9巻, 12号, 20201124
  30. A Comparison of Adrenalectomy and Eplerenone on Vascular Function in Patients with Aldosterone-producing Adenoma., The Journal of clinical endocrinology and metabolism, 105巻, 11号, 20201101
  31. Pre-impaired fasting glucose state is a risk factor for endothelial dysfunction: Flow-mediated Dilation Japan (FMD-J) study., BMJ open diabetes research & care, 8巻, 1号, 202010
  32. Vascular function is further impaired in subjects aged 80 years or older., Hypertension research : official journal of the Japanese Society of Hypertension, 43巻, 9号, pp. 914-921, 202009
  33. Increased arterial stiffness and cardiovascular risk prediction in controlled hypertensive patients with coronary artery disease: post hoc analysis of FMD-J (Flow-mediated Dilation Japan) Study A., Hypertension research : official journal of the Japanese Society of Hypertension, 43巻, 8号, pp. 781-790, 202008
  34. Hematocrit, hemoglobin and red blood cells are associated with vascular function and vascular structure in men., Scientific reports, 10巻, 1号, pp. 11467-11467, 20200710
  35. Relationship between high-density lipoprotein cholesterol levels and endothelial function in women: a cross-sectional study., BMJ open, 10巻, 7号, pp. e038121, 20200707
  36. Diagnostic Criteria of Flow-Mediated Vasodilation for Normal Endothelial Function and Nitroglycerin-Induced Vasodilation for Normal Vascular Smooth Muscle Function of the Brachial Artery., Journal of the American Heart Association, 9巻, 2号, pp. e013915, 20200121

受賞

  1. 2024年02月, 第53回日本心脈管作動物質学会 若手研究者奨励賞 最優秀演題賞, 日本心脈管作動物質学会
  2. 2021年11月, 第125回日本内科学会中国地方会YIA, 日本内科学会
  3. 2021年05月, 第21回日本NO学会 YIA優秀演題賞, 日本NO学会
  4. 2012年03月, 広島大学病院初期研修医ベストレジデント賞, 広島大学病院