清水 誠一SEIICHI SHIMIZU

Last Updated :2025/03/03

所属・職名
病院（医）　寄附講座助教
メールアドレス
seshimizhiroshima-u.ac.jp
自己紹介
外科医・日本外科学会指導医・日本移植学会認定医・日本消化器外科学会指導医・日本肝臓学会専門医・日本透析学会専門医 肝胆膵外科・移植外科・肝臓移植・腎臓移植・膵臓移植・小児移植・NK療法・

基本情報

主な職歴

  • 2005年04月20日, 2007年03月31日, 広島大学, 病院, 医員（研修医）
  • 2007年04月, 2009年03月, 安佐市民病院, 医員
  • 2009年04月, 2010年03月, 中国労災病院, 医員
  • 2010年04月, 2010年09月, 土谷総合病院, 医師
  • 2010年10月01日, 2011年03月31日, 広島大学, 病院, 医科診療医
  • 2011年04月, 2012年03月, 安佐市民病院, 医員
  • 2015年10月01日, 2018年03月31日, 広島大学, 病院, 医科診療医
  • 2018年04月01日, 2018年08月31日, 広島大学, 病院, 助教
  • 2018年09月01日, 2024年03月31日, 国立成育医療研究センター, 臓器移植センター, 医員

学位

  • 博士（医学）　(広島大学)

教育活動

授業担当

  1. 2024年, 博士課程・博士課程後期, セメスター（前期）, 消化器・移植外科学特別演習
  2. 2024年, 博士課程・博士課程後期, セメスター（後期）, 消化器・移植外科学特別演習
  3. 2024年, 博士課程・博士課程後期, セメスター（前期）, 消化器・移植外科学特別研究
  4. 2024年, 博士課程・博士課程後期, セメスター（後期）, 消化器・移植外科学特別研究

研究活動

学術論文（★は代表的な論文）

  1. A case report on the successful perioperative management of hepatectomy for hepatocellular carcinoma in a patient with von Willebrand disease, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 44巻, pp. 131-134, 2018
    DOIを用いた論文検索結果へのリンク
  2. Hepatectomy versus stereotactic body radiotherapy for primary early hepatocellular carcinoma: A propensity-matched analysis in a single institution, SURGERY, 164巻, 2号, pp. 219-226, 201808
    DOIを用いた論文検索結果へのリンク
  3. Synchronous double cancers of primary hepatic adenosquamous carcinoma and hepatocellular carcinoma: report of a case., Surgery today, 43巻, 4号, 2013
  4. Intraoperative assessment of tissue oxygen saturation of the remnant stomach by near-infrared spectroscopy in two cases of pancreatectomy following gastrectomy., International journal of surgery case reports, 22巻, 2016
  5. Intrahepatic cholangiocarcinoma coinciding with a liver metastasis from a rectal carcinoma: a case report., Surgical case reports, 2巻, 1号, 2016
  6. Elective laparoscopic deroofing to treat the spontaneous rupture of a large simple liver cyst: a case report., Surgical case reports, 2巻, 1号, 2016
  7. Fc-gamma receptor 3A polymorphism predicts the incidence of urinary tract infection in kidney-transplant recipients., Human immunology, 78巻, 4号, 2017
  8. Prediction of recurrence following hepatectomy in patients with hepatitis C virus infection-related hepatocellular carcinoma who achieved a sustained virological response., Hepatology research : the official journal of the Japan Society of Hepatology, 47巻, 11号, 2017
  9. Biliary-duodenal anastomosis using magnetic compression following massive resection of small intestine due to strangulated ileus after living donor liver transplantation: a case report., Surgical case reports, 3巻, 1号, 2017
  10. Application of endobronchial ultrasonography in laparoscopic liver segmentectomy in an animal model., Asian journal of endoscopic surgery, 10巻, 2号, 2017
  11. Effect of Fc-gamma Receptor Polymorphism on Rituximab-Mediated B Cell Depletion in ABO-Incompatible Adult Living Donor Liver Transplantation., Transplantation direct, 3巻, 6号, 2017
  12. Aggressive angiomyxoma of the liver: a case report and literature review., Surgical case reports, 3巻, 1号, 2017
  13. Utility of hepatobiliary scintigraphy for recurrent reflux cholangitis following choledochojejunostomy: A case report., International journal of surgery case reports, 42巻, 2018
  14. Significant association between FOXP3 gene polymorphism and steroid-resistant acute rejection in living donor liver transplantation., Hepatology communications, 1巻, 5号, 2017
  15. A case report on the successful perioperative management of hepatectomy for hepatocellular carcinoma in a patient with von Willebrand disease., International journal of surgery case reports, 44巻, 2018
  16. Hepatectomy versus stereotactic body radiotherapy for primary early hepatocellular carcinoma: A propensity-matched analysis in a single institution., Surgery, 164巻, 2号, 2018
  17. Impact of Abdominal Aortic Calcification Among Liver Transplantation Recipients., Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 25巻, 1号, 2019
  18. Independent risk factors that predict bile leakage after hepatectomy for hepatocellular carcinoma: Cohort study., International journal of surgery (London, England), 57巻, 2018
  19. Polymorphisms in TRAIL predict long-term survival and extrahepatic recurrence following initial hepatectomy for hepatocellular carcinoma., Journal of hepato-biliary-pancreatic sciences, 25巻, 8号, 2018
  20. Reply: Hepatectomy versus stereotactic body radiotherapy for primary early hepatocellular carcinoma: A propensity -matched analysis in a single institution., Surgery, 165巻, 5号, 2019
  21. Risk Factors for Refractory Ascites After Living Donor Liver Transplant., Transplantation proceedings, 51巻, 5号, 2019
  22. Successful Resection of Solitary Abdominal Wall Metastasis of Sarcomatous Intrahepatic Cholangiocarcinoma., Case reports in gastroenterology, 13巻, 1号, 2019
  23. Alcohol Use Disorders Identification Test-consumption Predicts the Risk of Excessive Alcohol Consumption After Liver Transplantation., Transplantation proceedings, 51巻, 6号, 2019
  24. Management of Refractory Ascites for Liver Transplant Candidates: A Novel Cell-free and Concentrated Ascites Reinfusion Therapy., Transplantation proceedings, 51巻, 8号, 2019
  25. Hepatic epithelioid hemangioendothelioma successfully treated with living donor liver transplantation: A case report and literature review., Clinical case reports, 8巻, 1号, 2020
  26. Rapidly Progressive Invasive Urothelial Carcinoma With Flat and Infiltrative Growth Pattern in the Graft Kidney After Living-Related Kidney Transplantation: A Case Report., Transplantation proceedings, 52巻, 9号, 2020
  27. Analysis of Risk Factors Affecting Incidence of Osteoporosis and Fragility Fractures in Liver Transplant Recipients., Annals of transplantation, 26巻, 2021
  28. ★, Adoptive immunotherapy overcomes genetic susceptibility to bloodstream infections due to fc-gamma receptor polymorphisms after liver transplantation., American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 22巻, 10号, 2022
  29. Arteriosclerosis Decreases Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Expression on Liver Natural Killer Cells in Living Donor Liver Transplantation., Transplantation proceedings, 55巻, 4号, 2023
  30. Donor Age Correlates With Liver-Resident Natural Killer Cell Activity in Adoptive Immunotherapy Using Donor Liver Natural Killer Cells in Liver Transplantation., Transplantation proceedings, 2024
  31. Macroscopic Characteristics of the Native Liver in Children With MPV17-Related Mitochondrial DNA Depletion Syndrome: An Indication for Performing Liver Transplantation?, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 28巻, 3号, 2022
  32. ★, Surgical technique and the long-term outcomes of pediatric living donor domino liver transplantation from patients with maple syrup urine disease., Pediatric transplantation, 26巻, 2号, 2022
  33. Quantification of Maternal Microchimeric Cells in the Liver of Children With Biliary Atresia., Journal of pediatric gastroenterology and nutrition, 74巻, 4号, 2022
  34. Transhepatic Coil Embolization for Ectopic Varices After Pediatric Liver-intestine Transplantation., Transplantation, 106巻, 4号, 2022
  35. Acute Antibody-mediated Rejection Coexisting With T Cell-mediated Rejection in Pediatric ABO-incompatible Transplantation., Transplantation direct, 8巻, 9号, 2022
  36. Preemptive liver transplant in two patients with primary hyperoxaluria type 1: Clinical significance of nephrolithiasis and nephrocalcinosis., Pediatric transplantation, 26巻, 8号, 2022
  37. Investigation on the Usefulness of Sulfamethoxazole Trimethoprim Combination Small Tablets in Pediatric Pharmacotherapy: A Single Center Observational Study Using a Questionnaire., Children (Basel, Switzerland), 9巻, 10号, 2022
  38. Strategy for hepatoblastoma with major vascular involvement: A guide for surgical decision-making., Surgery, 173巻, 2号, 2023
  39. Early Detection of Epstein-Barr Virus as a Risk Factor for Chronic High Epstein-Barr Viral Load Carriage at a Living-donor-dominant Pediatric Liver Transplantation Center., Transplantation, 107巻, 6号, 2023
  40. Significance of a multidisciplinary approach to congenital extrahepatic portosystemic shunt: A changing paradigm for the treatment., Hepatology research : the official journal of the Japan Society of Hepatology, 53巻, 6号, 2023
  41. ★, Successful pediatric liver transplantation case with a positive SARS-CoV-2 test at the time of transplant., Hepatology research : the official journal of the Japan Society of Hepatology, 53巻, 6号, 2023
  42. Gallstone ileus at 17 years after living donor liver transplantation: A case report., Pediatric transplantation, 27巻, 4号, 2023
  43. The role of living-donor liver transplantation in children with an advanced malignant rhabdoid tumor of the liver in the era of transplant oncology: Case report and literature review., Pediatric blood & cancer, 70巻, 11号, 2023
  44. Portal vein pressure and flow modulation in pediatric liver transplantation., Pediatric transplantation, 27巻, 7号, 2023
  45. The role of portal hemodynamics in pediatric living donor liver transplantation., Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 30巻, 1号, 2024
  46. The role of liver transplantation in COACH syndrome (Joubert syndrome with congenital hepatic fibrosis): A review of the literature., Pediatric transplantation, 28巻, 1号, 2024
  47. Intestinal Atp8b1 dysfunction causes hepatic choline deficiency and steatohepatitis., Nature communications, 14巻, 1号, 2023
  48. "Reduced Size Liver Grafts in Pediatric Liver Transplantation; Technical Considerations"., Journal of clinical and experimental hepatology, 14巻, 3号, 2024
  49. Living-donor liver transplantation for methylmalonic acidemia patient with hepatocellular carcinoma: A case report and literature review., Pediatric transplantation, 28巻, 2号, 2024
  50. Technical Considerations in Liver Transplantation for Biliary Atresia With Situs Inversus., Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 25巻, 9号, 2019
  51. The Outcomes of Portal Vein Reconstruction With Vein Graft Interposition in Pediatric Liver Transplantation for Small Children With Biliary Atresia., Transplantation, 104巻, 1号, 2020
  52. Sequential Deceased Donor Intestine Transplantation Followed by Living Donor Liver Transplantation, Also Known as Hybrid Intestine-liver Transplantation., Transplantation, 104巻, 1号, 2020
  53. Waiting list mortality for pediatric deceased donor liver transplantation in a Japanese living-donor-dominant program., Pediatric transplantation, 23巻, 8号, 2019
  54. Outcomes of 50 Cases of Pediatric Liver Transplantation for Intrapulmonary Shunt While Considering the Deteriorated Prognosis of Severe Intrapulmonary Shunt Patients., Transplantation proceedings, 51巻, 8号, 2019
  55. Longterm Outcomes of Living Donor Liver Transplantation for Glycogen Storage Disease Type 1b., Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 26巻, 1号, 2020
  56. Etiology of liver dysfunction after liver transplantation in children with metabolic disorders., Hepatology research : the official journal of the Japan Society of Hepatology, 50巻, 5号, 2020
  57. Living donor liver transplantation for congenital hepatic fibrosis in children., Pathology international, 70巻, 6号, 2020
  58. Efficacy of Antithymocyte Globulin Treatment for Severe Centrilobular Injury Following Pediatric Liver Transplant: Clinical Significance of Monitoring Lymphocyte Subset., Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 18巻, 3号, 2020
  59. Outcome for Pediatric Recipients of Macrosteatotic Liver Grafts From Living Donors., Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 26巻, 7号, 2020
  60. Late T cell-mediated rejection may contribute to poor outcomes in adolescents and young adults with liver transplantation., Pediatric transplantation, 24巻, 4号, 2020
  61. Living-donor liver transplantation for liver hemorrhaging due to peliosis hepatis in X-linked myotubular myopathy: Two cases and a literature review., American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 20巻, 9号, 2020
  62. Living-donor liver transplantation providing an adequate chemotherapy for a pediatric patient with anaplastic large cell lymphoma complicated with liver failure due to the aggravation of biliary hepatopathy by secondary hemophagocytic lymphohistiocytosis., International journal of hematology, 112巻, 6号, 2020
  63. Efficacy of intraoperative cine-portogram for complicated portal vein reconstruction in pediatric living donor liver transplantation., Pediatric transplantation, 25巻, 2号, 2021
  64. Current status of pediatric deceased donor liver transplantation: Lessons learned from a high-volume center in Japan where living donation remains predominant., Journal of hepato-biliary-pancreatic sciences, 28巻, 11号, 2021
  65. Impact of sarcopenia in infants with liver transplantation for biliary atresia., Pediatric transplantation, 25巻, 5号, 2021
  66. The extracorporeal circulation with transdiaphragmatic approach in living-donor liver transplantation for HB with atrial extension of tumor thrombus: A case report., Pediatric transplantation, 25巻, 7号, 2021
  67. Fatal Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis with virus-infected T cells after pediatric multivisceral transplantation: A proof-of-concept case report., Pediatric transplantation, 25巻, 3号, 2021
  68. Impact of prolonged clamping of the portal vein during liver transplantation in infants with biliary atresia: renewed interest in a long-standing issue., Surgery today, 51巻, 8号, 2021
  69. The morphological and histopathological assessment of Alagille syndrome with extrahepatic bile duct obstruction: the importance of the differential diagnosis with subgroup "o" biliary atresia., Pediatric surgery international, 37巻, 9号, 2021
  70. Outcomes of liver transplantation for mitochondrial respiratory chain disorder in children., Pediatric transplantation, 25巻, 8号, 2021
  71. Immunological features and complications in patients with glycogen storage disease 1b after living donor liver transplantation., Pediatric transplantation, 25巻, 8号, 2021
  72. Comparative study of open and laparoscopic Kasai portoenterostomy in children undergoing living donor liver transplantation for biliary atresia., Pediatric surgery international, 37巻, 12号, 2021
  73. Optimal liver transplant procedure in progressive familial intrahepatic cholestasis type 1 treated with biliary diversion or intestinal transplantation: Lessons learned from three cases treated with different approaches., Pediatric transplantation, 27巻, 6号, 2023

受賞

  1. 2015年11月11日, Mentee-Mentor Awards, 14th Transplantation Science Symposium
  2. 2015年04月03日, 広島大学学生表彰, 広島大学
  3. 2014年07月26日, Young Investigator Awards, World Transplant Congress