Yukihito Higashi

Last Updated :2017/09/22

Affiliations, Positions
Research Institute for Radiation Biology and Medicine, ., Professor
E-mail
yhigashihiroshima-u.ac.jp
Other Contact Details
1-2-3 Kasumi Minami-ku Hiroshima, Japan
TEL : (+81)82-257-5831 FAX : (+81)

Basic Information

Educational Backgrounds

  • Hiroshima University, Faculty of Medicine, Japan, 1982/04, 1988/03

Academic Degrees

  • Medical Doctor, Hiroshima University

Educational Activity

  • School of Medicine:Program of Medicine, Graduate School of Biomedical & Health Sciences:Medical and Dental Sciences Major, Graduate School of Biomedical & Health Sciences:Biomedical Sciences Major

In Charge of Primary Major Programs

  • Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Boundary medicine;Laboratory medicine

Research Keywords

  • oxidative stress
  • myocradial regeneration
  • nitric oxide
  • angiogenesis
  • endothelial function
  • hypertension

Educational Activity

Course in Charge

  1. 2017, Undergraduate Education, Intensive, Practice for medical research
  2. 2017, Undergraduate Education, First Semester, Molecular Biology in Medicine
  3. 2017, Graduate Education (Doctoral Program) , Second Semester, Advanced Lecture on Creation and Development of Biomedical Sciences
  4. 2017, Graduate Education (Doctoral Program) , Second Semester, Advanced Lecture on Creation and Development of Biomedical Sciences
  5. 2017, Graduate Education (Doctoral Program) , First Semester, Integrated radiation medical science
  6. 2017, Graduate Education (Doctoral Program) , First Semester, Integrated radiation medical science
  7. 2017, Graduate Education (Doctoral Program) , First Semester, Integrated radiation medical science
  8. 2017, Graduate Education (Doctoral Program) , First Semester, Integrated radiation medical science
  9. 2017, Graduate Education (Master's Program) , Second Semester, Pathologic basis of diseases
  10. 2017, Graduate Education (Master's Program) , First Semester, Seminar on Human Genetics
  11. 2017, Graduate Education (Master's Program) , Second Semester, Seminar on Human Genetics
  12. 2017, Graduate Education (Master's Program) , First Semester, Research on Human Genetics
  13. 2017, Graduate Education (Master's Program) , Second Semester, Research on Human Genetics
  14. 2017, Graduate Education (Doctoral Program) , First Semester, Advanced seminar on Human Genetics
  15. 2017, Graduate Education (Doctoral Program) , Second Semester, Advanced seminar on Human Genetics
  16. 2017, Graduate Education (Doctoral Program) , First Semester, Advanced research on Human Genetics
  17. 2017, Graduate Education (Doctoral Program) , Second Semester, Advanced research on Human Genetics

Research Activities

Academic Papers

  1. Baseline Characterization of Japanese Peripheral Arterial Disease Patients - Analysis of Surveillance of Cardiovascular Events in Antiplatelet-Treated Arteriosclerosis Obliterans Patients in Japan (SEASON) -, CIRCULATION JOURNAL, 80(3), 712-721, MAR 2016
  2. Perinatal Resveratrol Supplementation to Spontaneously Hypertensive Rat Dams Mitigates the Development of Hypertension in Adult Offspring, HYPERTENSION, 67(5), 1045-1052, MAY 2016
  3. Osteoporosis, osteoporotic fractures, and carotid artery calcification detected on panoramic radiographs in Japanese men and women, ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 121(6), 673-680, JUN 2016
  4. Relationship between serum triglyceride levels and endothelial function in a large community-based study, ATHEROSCLEROSIS, 249, 70-75, JUN 2016
  5. The Effect of Sitagliptin on Carotid Artery Atherosclerosis in Type 2 Diabetes: The PROLOGUE Randomized Controlled Trial, PLOS MEDICINE, 13(6), JUN 2016
  6. Rationale and design of a multicenter randomized study for evaluating vascular function under uric acid control using the xanthine oxidase inhibitor, febuxostat: the PRIZE study, CARDIOVASCULAR DIABETOLOGY, 15, JUN 18 2016
  7. Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma, CANCER SCIENCE, 107(5), 601-608, MAY 2016
  8. Nitroglycerine-induced vasodilation in coronary and brachial arteries in patients with suspected coronary artery disease, INTERNATIONAL JOURNAL OF CARDIOLOGY, 219, 312-316, SEP 15 2016
  9. Effect of Aldosterone-Producing Adenoma on Endothelial Function and Rho-Associated Kinase Activity in Patients With Primary Aldosteronism, HYPERTENSION, 65(4), 841-+, APR 2015
  10. Ratio of Serum Levels of AGEs to Soluble Form of RAGE Is a Predictor of Endothelial Function, DIABETES CARE, 38(1), 119-125, JAN 2015
  11. Endothelial dysfunction is associated with the severity of cerebral small vessel disease, HYPERTENSION RESEARCH, 38(4), 291-297, APR 2015
  12. Mesenchymal-stem-cell-derived exosomes accelerate skeletal muscle regeneration, FEBS LETTERS, 589(11), 1257-1265, MAY 8 2015
  13. Depletion of Uric Acid Due to SLC22A12 (URAT1) Loss-of-Function Mutation Causes Endothelial Dysfunction in Hypouricemia, CIRCULATION JOURNAL, 79(5), 1125-+, MAY 2015
  14. Assessment of Endothelial Function History, Methodological Aspects, and Clinical Perspectives, INTERNATIONAL HEART JOURNAL, 56(2), 125-134, MAR 2015
  15. Exogenous nitric oxide inhibits Rho-associated kinase activity in patients with angina pectoris: a randomized controlled trial, HYPERTENSION RESEARCH, 38(7), 485-490, JUL 2015
  16. Model-Based Evaluation of Reactive Hyperemia Using Strain-Gauge Plethysmography and Log-Linearized Viscoelastic Indices, JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING, 5(4), 334-341, APR 2015
  17. Rho-Associated Kinase Activity Is an Independent Predictor of Cardiovascular Events in Acute Coronary Syndrome, HYPERTENSION, 66(4), 892-899, OCT 2015
  18. Reliability of measurement of endothelial function across multiple institutions and establishment of reference values in Japanese, ATHEROSCLEROSIS, 242(2), 433-442, OCT 2015
  19. Promotion of skeletal muscle repair in a rat skeletal muscle injury model by local injection of human adipose tissue-derived regenerative cells, JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 9(10), 1150-1160, OCT 2015
  20. Reduction in blood pressure improves impaired nitroglycerine-induced vasodilation in patients with essential hypertension, HYPERTENSION RESEARCH, 38(12), 862-868, DEC 2015
  21. Effect of a Low-Intensity Pulsed Ultrasound Device, SX-1001, on Clinical Symptoms in Buerger Disease With Limb Ischemia, INTERNATIONAL HEART JOURNAL, 56(6), 632-638, NOV 2015
  22. Do incretins improve endothelial function?, CARDIOVASCULAR DIABETOLOGY, 13, JAN 15 2014
  23. Rho-Associated Kinase Activity Is a Predictor of Cardiovascular Outcomes, HYPERTENSION, 63(4), 856-864, APR 2014
  24. Poor Oral Health, That Is, Decreased Frequency of Tooth Brushing, Is Associated With Endothelial Dysfunction, CIRCULATION JOURNAL, 78(4), 950-954, APR 2014
  25. Oxidative stress and endothelial dysfunction: Clinical evidence and therapeutic implications, TRENDS IN CARDIOVASCULAR MEDICINE, 24(4), 165-169, MAY 2014
  26. A single consumption of curry improved postprandial endothelial function in healthy male subjects: a randomized, controlled crossover trial, NUTRITION JOURNAL, 13, JUN 28 2014
  27. Relationship between nitroglycerine-induced vasodilation and clinical severity of peripheral artery disease, ATHEROSCLEROSIS, 235(1), 65-70, JUL 2014
  28. Borderline Ankle-Brachial Index Value of 0.91-0.99 Is Associated With Endothelial Dysfunction, CIRCULATION JOURNAL, 78(7), 1740-+, JUL 2014
  29. Critical Role of Exogenous Nitric Oxide in ROCK Activity in Vascular Smooth Muscle Cells, PLOS ONE, 9(10), OCT 3 2014
  30. Autonomic nervous activation triggered during induction of reactive hyperemia exerts a greater influence on the measured reactive hyperemia index by peripheral arterial tonometry than on flow-mediated vasodilatation of the brachial artery in patients with hypertension, HYPERTENSION RESEARCH, 37(10), 914-918, OCT 2014
  31. Circulating endothelial progenitor cells and placental abruption in women with preeclampsia., Pregnancy Hypertens, 4(3), 203-208, 2014, July
  32. Circulating endothelial progenitor cells and placental abruption in women with preeclampsia, PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH, 4(3), 203-208, JUL 2014
  33. Mesenchymal stem cells ameliorate experimental peritoneal fibrosis by suppressing inflammation and inhibiting TGF-beta 1 signaling, KIDNEY INTERNATIONAL, 84(2), 297-307, AUG 2013
  34. Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer, INTERNATIONAL JOURNAL OF CANCER, 132(4), 813-823, FEB 15 2013
  35. Flow-Mediated Vasodilation and Anatomical Variation of the Brachial Artery (Double Brachial Artery) in Healthy Subjects and Patients With Cardiovascular Disease, CIRCULATION JOURNAL, 77(4), 1073-1080, APR 2013
  36. Nitroglycerine-Induced Vasodilation for Assessment of Vascular Function A Comparison With Flow-Mediated Vasodilation, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 33(6), 1401-+, JUN 2013
  37. Resistin-Like Molecule Is Abundantly Expressed in Foam Cells and Is Involved in Atherosclerosis Development, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 33(8), 1986-1993, AUG 2013
  38. Chronic Intake of Onion Extract Containing Quercetin Improved Postprandial Endothelial Dysfunction in Healthy Men, JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 32(3), 160-164, JUN 1 2013
  39. A novel noninvasive and simple method for assessment of endothelial function: Enclosed zone flow-mediated vasodilation (ezFMD) using an oscillation amplitude measurement, ATHEROSCLEROSIS, 229(2), 324-330, AUG 2013
  40. Age-dependent decrease in the chondrogenic potential of human bone marrow mesenchymal stromal cells expanded with fibroblast growth factor-2, CYTOTHERAPY, 15(9), 1062-1072, SEP 2013
  41. Autologous Bone-Marrow Mesenchymal Stem Cell Implantation and Endothelial Function in a Rabbit Ischemic Limb Model, PLOS ONE, 8(7), JUL 4 2013
  42. Association between Oral Health and the Risk of Lacunar Infarction in Japanese Adults, GERONTOLOGY, 59(6), 499-506, 2013
  43. Relationship between flow-mediated vasodilation and cardiovascular risk factors in a large community-based study, HEART, 99(24), 1837-1842, DEC 15 2013
  44. Hyperuricemia is independently associated with endothelial dysfunction in postmenopausal women but not in premenopausal women, BMJ OPEN, 3(11), 2013
  45. Geranylgeranylacetone, Heat Shock Protein 90/AMP-Activated Protein Kinase/Endothelial Nitric Oxide Synthase/Nitric Oxide Pathway, and Endothelial Function in Humans, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(1), 153-U350, JAN 2012
  46. Association of elevated plasma aldosterone-to-renin ratio with future cardiovascular events in patients with essential hypertension, JOURNAL OF HYPERTENSION, 30(12), 2322-2330, DEC 2012
  47. Xanthine Oxidoreductase Is Involved in Macrophage Foam Cell Formation and Atherosclerosis Development, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(2), 291-U282, FEB 2012
  48. Mineralocorticoid Receptor Blocker Eplerenone Improves Endothelial Function and Inhibits Rho-Associated Kinase Activity in Patients With Hypertension, CLINICAL PHARMACOLOGY & THERAPEUTICS, 91(2), 289-297, FEB 2012
  49. Hyperbilirubinemia, Augmentation of Endothelial Function, and Decrease in Oxidative Stress in Gilbert Syndrome, CIRCULATION, 126(5), 598-603, JUL 31 2012
  50. Striking crosstalk of ROCK signaling with endothelial function, JOURNAL OF CARDIOLOGY, 60(1-2), 1-6, JUL-AUG 2012
  51. A Multicenter Study Design to Assess the Clinical Usefulness of Semi-Automatic Measurement of Flow-Mediated Vasodilatation of the Brachial Artery, INTERNATIONAL HEART JOURNAL, 53(3), 170-175, MAY 2012
  52. Intima-Media Thickness of Brachial Artery, Vascular Function, and Cardiovascular Risk Factors, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(9), 2295-+, SEP 2012
  53. The therapeutic potential of ex vivo expanded CD133(+) cells derived from human peripheral blood for peripheral nerve injuries, JOURNAL OF NEUROSURGERY, 117(4), 787-794, OCT 2012
  54. Endothelial dysfunction and hypertension in aging, HYPERTENSION RESEARCH, 35(11), 1039-1047, NOV 2012
  55. Novel non-invasive method of measurement of endothelial function: enclosed-zone flow-mediated dilatation (ezFMD), MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 50(12), 1239-1247, DEC 2012
  56. Measurement of Rho-associated kinase (ROCK) activity in humans: Validity of leukocyte p-MBS/t-MBS in comparison with vascular response to fasudil, ATHEROSCLEROSIS, 214(1), 117-121, JAN 2011
  57. Vascular Function and Circulating Progenitor Cells in Thromboangitis Obliterans (Buerger's Disease) and Atherosclerosis Obliterans, HYPERTENSION, 57(1), 70-U204, JAN 2011
  58. Calcium channel blocker and Rho-associated kinase activity in patients with hypertension, JOURNAL OF HYPERTENSION, 29(2), 373-379, FEB 2011
  59. Autologous Bone-Marrow Mononuclear Cell Implantation Reduces Long-Term Major Amputation Risk in Patients With Critical Limb Ischemia A Comparison of Atherosclerotic Peripheral Arterial Disease and Buerger Disease, CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 4(1), 15-25, FEB 2011
  60. Relationships Among Hyperuricemia, Metabolic Syndrome, and Endothelial Function, AMERICAN JOURNAL OF HYPERTENSION, 24(7), 770-774, JUL 2011
  61. Rho-Associated Kinase Activity, Endothelial Function, and Cardiovascular Risk Factors, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 31(10), 2353-2359, OCT 2011
  62. Flow-mediated vasodilation is augmented in a corkscrew collateral artery compared with that in a native artery in patients with thromboangiitis obliterans (Buerger disease), JOURNAL OF VASCULAR SURGERY, 54(6), 1689-1697, DEC 2011
  63. Pioglitazone improves endothelium-dependent vasodilation in hypertensive patients with impaired glucose tolerance in part through a decrease in oxidative stress, ATHEROSCLEROSIS, 210(2), 521-524, JUN 2010
  64. Classification of Corkscrew Collaterals in Thromboangiitis Obliterans (Buerger's Disease) - Relationship Between Corkscrew Type and Prevalence of Ischemic Ulcers, CIRCULATION JOURNAL, 74(8), 1684-1688, AUG 2010
  65. Endothelial function in subjects with isolated low HDL cholesterol: role of nitric oxide and circulating progenitor cells, AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 298(2), E202-E209, FEB 2010
  66. Sarpogrelate Hydrochloride, a Selective 5-hydroxytryptamine(2A) Antagonist, Augments Autologous Bone Marrow Mononuclear Cell Implantation-induced Improvement in Endothelium-dependent Vasodilation in Patients With Critical Limb Ischemia, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 55(1), 56-61, JAN 2010
  67. Increased leukocyte rho kinase (ROCK) activity and endothelial dysfunction in cigarette smokers, HYPERTENSION RESEARCH, 33(4), 354-359, APR 2010
  68. Mesenchymal stem cells enhance growth and metastasis of colon cancer, INTERNATIONAL JOURNAL OF CANCER, 127(10), 2323-2333, NOV 15 2010
  69. Study Design of SEASON Registry Prospective Surveillance of Cardiovascular Events in Antiplatelet-Treated ArterioSclerosis Obliterans Patients in JapaN (SEASON), INTERNATIONAL HEART JOURNAL, 51(5), 337-342, SEP 2010
  70. Edaravone for the treatment of acute cerebral infarction: role of endothelium-derived nitric oxide and oxidative stress, EXPERT OPINION ON PHARMACOTHERAPY, 10(2), 323-331, FEB 2009
  71. Endothelial Function and Oxidative Stress in Cardiovascular Diseases, CIRCULATION JOURNAL, 73(3), 411-418, MAR 2009
  72. Cigarette Smoking Abolishes Ischemic Preconditioning-Induced Augmentation of Endothelium-Dependent Vasodilation, HYPERTENSION, 53(4), 674-U151, APR 2009
  73. Dietary Phosphorus Acutely Impairs Endothelial Function, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 20(7), 1504-1512, JUL 2009
  74. Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease, ATHEROSCLEROSIS, 206(2), 604-610, OCT 2009
  75. Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients, HYPERTENSION, 51(2), 446-453, FEB 1 2008
  76. Coronary vasospasm produces reversible perfusion defects observed during adenosine triphosphate stress myocardial single-photon emission computed tomography, CLINICAL CARDIOLOGY, 31(7), 310-316, JUL 2008
  77. Endothelial progenitor cells: Therapeutic target for cardiovascular diseases, JOURNAL OF PHARMACOLOGICAL SCIENCES, 108(1), 1-6, SEP 2008
  78. Relationship between Augmentation Index and Flow-Mediated Vasodilation in the Brachial Artery, HYPERTENSION RESEARCH, 31(7), 1293-1298, JUL 2008
  79. Aging and Hypertension Are Independent Risk Factors for Reduced Number of Circulating Endothelial Progenitor Cells, AMERICAN JOURNAL OF HYPERTENSION, 21(11), 1203-1209, NOV 2008
  80. Flow-Mediated Vasodilation as a Diagnostic Modality for Vascular Failure, HYPERTENSION RESEARCH, 31(12), 2105-2113, DEC 2008
  81. Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 49(4), 221-227, APR 2007
  82. Roles of Rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 49(6), 698-705, FEB 13 2007
  83. Interaction of obesity and skeletal bone mineral density in tooth retention in Japanese postmenopausal women, MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 14(3), 500-504, MAY-JUN 2007
  84. Measurement of flow-mediated vasodilation of the brachial artery - A comparison of measurements in the seated and supine positions, CIRCULATION JOURNAL, 71(5), 736-740, MAY 2007
  85. Repetition of ischemic preconditioning augments endothelium-dependent vasodilation in humans - Role of endothelium-derived nitric oxide and endothelial progenitor cells, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 27(6), 1403-1410, JUN 2007
  86. Acute moderate-intensity exercise induces vasodilation through oxide bioavailiability an increase in nitric in humans, AMERICAN JOURNAL OF HYPERTENSION, 20(8), 825-830, AUG 2007
  87. Selection of common markers for bone marrow stromal cells from various bones using real-time RT-PCR: Effects of passage number and donor age, TISSUE ENGINEERING, 13(10), 2405-2417, OCT 2007
  88. Pycnogenol (R), French maritime pine bark extract, augments endothelium-dependent vasodilation in humans, HYPERTENSION RESEARCH, 30(9), 775-780, SEP 2007
  89. Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production, ATHEROSCLEROSIS, 186(2), 390-395, JUN 2006
  90. Oxidative stress, endothelial function and angiogenesis induced by cell therapy and gene therapy, CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 7(2), 109-116, APR 2006
  91. Autologous bone marrow mononuclear cell implantation induces angiogenesis and bone regeneration in a patient with compartment syndrome, CIRCULATION JOURNAL, 70(10), 1362-1364, OCT 2006
  92. Effects of acute administration of caffeine on vascular function, AMERICAN JOURNAL OF CARDIOLOGY, 98(11), 1538-1541, DEC 1 2006
  93. Vascular function in patients with lower extremity peripheral arterial disease: a comparison of functions in upper and lower extremities, ATHEROSCLEROSIS, 178(1), 179-185, JAN 2005
  94. The nicorandil-induced vasodilation in humans is inhibited by miconazole, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 45(4), 290-294, APR 2005
  95. Association of Helicobacter pylori infection with systemic inflammation and endothelial dysfunction in healthy male subjects, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 45(8), 1219-1222, APR 19 2005
  96. Molecular markers distinguish bone marrow mesenchymal stem cells from fibroblasts, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 332(1), 297-303, JUN 24 2005
  97. Smoking, endothelial function, and Rho-kinase in humans, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 25(12), 2630-2635, DEC 2005
  98. Relationship between endothelial function in the coronary and brachial arteries, CLINICAL CARDIOLOGY, 28(10), 460-466, OCT 2005
  99. Adrenomedullin causes coronary vasodilation in humans - Effects of inhibition of nitric oxide synthesis, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 46(4), 534-539, OCT 2005
  100. Beneficial effect of type calcium channel blockers on endothelial function in patients with essential hypertension, HYPERTENSION RESEARCH, 28(11), 889-894, NOV 2005
  101. Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia, CIRCULATION, 109(10), 1215-1218, MAR 16 2004
  102. Exercise and endothelial function: Role of endothelium-derived nitric oxide and oxidative stress in healthy subjects and hypertensive patients, PHARMACOLOGY & THERAPEUTICS, 102(1), 87-96, APR 2004
  103. Tooth loss is associated with an increased risk of hypertension in postmenopausal women, HYPERTENSION, 43(6), 1297-1300, JUN 2004
  104. Relation between C reactive protein concentrations and coronary microvascular endothelial function, HEART, 90(7), 750-754, JUL 2004
  105. Forearm endothelial function and bone mineral loss in postmenopausal women, ATHEROSCLEROSIS, 176(2), 387-392, OCT 2004
  106. Effect of edaravone, a novel free radical scavenger, on endothelium-dependent vasodilation in smokers, AMERICAN JOURNAL OF CARDIOLOGY, 94(8), 1070-1073, OCT 15 2004
  107. Apolipoprotein E phenotype affects the malondialdehyde-modified LDL concentration and forearm endothelial function in postmenopausal women, CLINICAL ENDOCRINOLOGY, 61(5), 619-625, NOV 2004
  108. Myocardial bridging increases the risk of coronary spasm, CLINICAL CARDIOLOGY, 26(8), 377-383, AUG 2003
  109. Leptin causes nitric-oxide independent coronary artery vasodilation in humans, HYPERTENSION RESEARCH, 26(2), 147-152, FEB 2003
  110. A comparison of low-dose and standard-dose oral estrogen on forearm endothelial function in early postmenopausal women, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 88(3), 1303-1309, MAR 2003
  111. Smoking activates Rho-kinase in smooth muscle cells of forearm vasculature in humans, HYPERTENSION, 41(5), 1102-1105, MAY 2003
  112. PDE5 inhibitor sildenafil citrate augments endothelium-dependent vasodilation in smokers, HYPERTENSION, 41(5), 1106-1110, MAY 2003
  113. Comparison of forearm endothelial function between premenopausal and postmenopausal women with or without hypercholesterolemia, MATURITAS, 44(4), 307-315, APR 25 2003
  114. Low body mass index is a risk factor for impaired endothelium-dependent vasodilation in humans: Role of nitric oxide and oxidative stress, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 42(2), 256-263, JUL 16 2003
  115. Effect of different intensities of exercise on endothelium-dependent vasodilation in humans - Role of endothelium-dependent nitric oxide and oxidative stress, CIRCULATION, 108(5), 530-535, AUG 5 2003
  116. Detection of vascular disease risk in women by panoramic radiography, JOURNAL OF DENTAL RESEARCH, 82(10), 838-843, OCT 2003
  117. Effect of amlodipine and cilazapril treatment on platelet Ca2+ handling in spontaneously hypertensive rats, HYPERTENSION RESEARCH, 26(11), 901-906, NOV 2003
  118. Response of the left anterior descending coronary artery to Acetylcholine in patients with chest pain and angiographically normal coronary arteries, AMERICAN JOURNAL OF CARDIOLOGY, 92(12), 1394-1398, DEC 15 2003
  119. New methods to evaluate endothelial function: Method for assessing endothelial function in humans using a strain-gauge plethysmography: Nitric oxide-dependent and -independent vasodilation, JOURNAL OF PHARMACOLOGICAL SCIENCES, 93(4), 399-404, DEC 2003
  120. Excess norepinephrine impairs both endothelium-dependent and -independent vasodilation in patients with pheochromocytoma, HYPERTENSION, 39(2), 513-518, FEB 2002
  121. Renal endothelial dysfunction and hypertension, JOURNAL OF DIABETES AND ITS COMPLICATIONS, 16(1), 103-107, JAN-FEB 2002
  122. A low-calorie diet improves endothelium-dependent vasodilation in obese patients with essential hypertension, AMERICAN JOURNAL OF HYPERTENSION, 15(4), 302-309, APR 2002
  123. Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals, AMERICAN JOURNAL OF HYPERTENSION, 15(4), 326-332, APR 2002
  124. Severity of hypertension affects improved resistance artery endothelial function by angiotensin-converting enzyme inhibition, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 39(5), 668-676, MAY 2002
  125. Leptin causes vasodilation in humans, HYPERTENSION RESEARCH, 25(2), 161-165, MAR 2002
  126. Endothelial function and oxidative stress in renovascular hypertension, NEW ENGLAND JOURNAL OF MEDICINE, 346(25), 1954-1962, JUN 20 2002
  127. Combination therapy of low-dose medroxyprogesterone acetate and oral estrogen does not affect endothelial function in the forearms of postmenopausal women, MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 9(5), 360-366, SEP-OCT 2002
  128. Effect of alcohol consumption on endothelial function in men with coronary artery disease, ATHEROSCLEROSIS, 165(1), 145-152, NOV 2002
  129. Hormone replacement effects on endothelial function measured in the forearm resistance artery in normocholesterolemic and hypercholesterolemic postmenopausal women, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 87(10), 4634-4641, OCT 2002
  130. Circadian variation of blood pressure and endothelial function in patients with essential hypertension: A comparison of dippers and non-dippers, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 40(11), 2039-2043, DEC 4 2002
  131. A noninvasive measurement of reactive hyperemia that can be used to assess resistance artery endothelial function in humans, AMERICAN JOURNAL OF CARDIOLOGY, 87(1), 121-+, JAN 1 2001
  132. Effect of the angiotensin-converting enzyme inhibitor imidapril on reactive hyperemia in patients with essential hypertension: Relationship between treatment periods and resistance artery endothelial function, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 37(3), 863-870, MAR 1 2001
  133. Effect of estrogen replacement therapy on endothelial function in peripheral resistance arteries in normotensive and hypertensive postmenopausal women, HYPERTENSION, 37(2), 651-657, FEB 2001
  134. Relationship between the angiotensin-converting enzyme genotype and the forearm vasodilator response to estrogen replacement therapy in postmenopausal women, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 37(6), 1529-1535, MAY 2001
  135. Oral estrogen replacement therapy increases forearm reactive hyperemia accompanied by increases in serum levels of nitric oxide in postmenopausal women, GYNECOLOGICAL ENDOCRINOLOGY, 15(2), 150-157, APR 2001
  136. Non-dipper phenomenon in essential hypertension is related to blunted nocturnal rise and fall of sympatho-vagal nervous activity and progress in retinopathy, AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, 88(3), 181-186, MAY 14 2001
  137. Effects of angiotensin-(1-7) on forearm circulation in normotensive subjects and patients with essential hypertension, HYPERTENSION, 38(1), 90-94, JUL 2001
  138. Effect of obesity on endothelium-dependent, nitric oxide-mediated vasodilation in normotensive individuals and patients with essential hypertension, AMERICAN JOURNAL OF HYPERTENSION, 14(10), 1038-1045, OCT 2001
  139. Estrogen replacement therapy in postmenopausal women augments reactive hyperemia in the forearm by reducing angiotensin converting enzyme activity, ATHEROSCLEROSIS, 158(2), 391-397, OCT 2001
  140. Calorie restriction reduced blood pressure in obesity hypertensives by improvement of autonomic nerve activity and insulin sensitivity, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 38, S69-S74, OCT 2001
  141. Sodium chloride loading does not alter endothelium-dependent vasodilation of forearm vasculature in either salt-sensitive or salt-resistant patients with essential hypertension, HYPERTENSION RESEARCH, 24(6), 711-716, NOV 2001
  142. A comparison of angiotensin-converting enzyme inhibitors, calcium antagonists, beta-blockers and diuretic agents on reactive hyperemia in patients with essential hypertension: A multicenter study, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 35(2), 284-291, FEB 2000
  143. Abnormal magnesium status in patients with cardiovascular diseases, CLINICAL SCIENCE, 98(2), 175-181, FEB 2000
  144. Abnormal Ca2+ handling and increased Mg2+ permeability in platelets of hypertensive rats, HYPERTENSION RESEARCH, 23(6), 651-657, NOV 2000
  145. Troglitazone Improves Endothelium-Dependent Vasodilation in Essential Hypertensive Patients with Glucose Intolerance, Circulation journal : official journal of the Japanese Circulation Society, 67(0), 184-185, 20030301
  146. Council on Clinical Physiology: Evaluation of Vascular Endothelial Function, 48(9), 860-866, 20000925
  147. Abnormal Ca^<2+> Handling and Increased Mg^<2+> Permeability in Platelets of Hypertensive Rats, Hypertens Res, 23(6), 651-657, 20001101
  148. Sodium Chloride Loading Does Not Alter Endothelium-Dependent Vasodilation of Forearm Vasculature in Either Salt-Sensitive or Salt-Resistant Patients with Essential Hypertenseion, Hypertension Research, 24(6), 711-716, 20011101
  149. Leptin Causes Vasodilation in Humans, Hypertens Res, 25(2), 161-165, 20020301
  150. temic Magnisium Deficiency Disclosed by Magnesium Loading Test in Patients with Essential Hypertension, 18(1), 39-42, 19950301
  151. Effect of Amlodipine and Cilazapril Treatment on Platelet Ca^<2+> Handling in Spontaneously Hypertensive Rats, Hypertension Research, 26(11), 901-906, 20031101
  152. New Methods to Evaluate Endothelial Function : Method for Assessing Endothelial Function in Humans Using a Strain-Gauge Plethysmography : Nitric Oxide-Dependent and-Independent Vasodilation, The Japanese Journal of Pharmacology, 93(4), 399-404, 20031201
  153. Beneficial Effect of T-Type Calcium Channel Blockers on Endothelial Function in Patients with Essential Hypertension, Hypertens Res, 28(11), 889-894, 20051101
  154. Pycnogenol^【○!R】, French Maritime Pine Bark Extract, Augments Endothelium-Dependent Vasodilation in Humans, 30(9), 775-780, 20070901
  155. Vascular Endothelium Dysfunction as the First Phase of Arteriosclerosis, Nihon Naika Gakkai Kaishi, 96(8), 1717-1723, 20070810
  156. Consensus Statement on the Measurement of Flow-Mediated vasoDilation as a Surrogate Marker of Cardiovascular Diseases, 38(5), 305-309, 20070930
  157. The Effects of Aerobic Exercise on Endothelium-dependent Vasodilation in Humans, Journal of exercise physiology, 17(2), 87-91, 20020420
  158. Endothelial Progenitor Cells : Therapeutic Target for Cardiovascular Diseases, The Japanese Journal of Pharmacology, 108(1), 1-6, 20080920
  159. Relationship between Augmentation Index and Flow-Mediated Vasodilation in the Brachial Artery, Hypertens Res, 31(7), 1293-1298, 20080701
  160. Flow-Mediated Vasodilation as a Diagnostic Modality for Vascular Failure, HYPERTENSION RESEARCH, 31(12), 2105-2113, 20081201
  161. Acute Myocardial Infarction, in which the Culprit Lesion was within the Stented Portion, occurring Nine Years after Implantation of a Bare Metal Stent, 23(5), 376-380, 20081010
  162. Increased leukocyte rho kinase (ROCK) activity and endothelial dysfunction in cigarette smokers, Hypertens Res, 33(4), 354-359, 20100401
  163. Measurement of Endothelial Function for Assessment of Pharmacological Interventions : from FMD and Plethysmography to Biomarkers, 40(4), 201S-202S, 20090731
  164. Classification of Corkscrew Collaterals in Thromboangiitis Obliterans (Buerger's Disease) : Relationship Between Corkscrew Type and Prevalence of Ischemic Ulcers, 74(8), 1684-1688, 20100725
  165. Is Cell Therapy Promising or Lost in Translation in Patients With Acute Myocardial Infarction?, JAPANESE CIRCULATION JOURNAL, 75(3), 546-547, 20110225
  166. Endothelial Function and Atherosclerosis, 49(5), 385-390, 20091025
  167. Peripheral Arterial Disease and Endothelial Function, 50(6), 673-679, 20101225
  168. Role of Endothelial Function, Japanese journal of clinical sports medicine, 19(3), 404-407, 20110831
  169. Noninvasive Evaluation of Endothelial Function Based on Dilation Rate of Integrated Air-Cuff Plethysmogram, 82(3), 259-266, 20120601
  170. How to Use Ezetimibe as an Anti-Atherogenic Agent via Inhibition of Rho-Kinase, JAPANESE CIRCULATION JOURNAL, 76(8), 1836-1837, 20120725
  171. A Log-linearized Arterial Viscoelastic Index and Its Application to Carotid Ultrasonography, 48(9), 563-570, 20120930
  172. Flow-Mediated Vasodilation and Anatomical Variation of the Brachial Artery (Double Brachial Artery) in Healthy Subjects and Patients With Cardiovascular Disease, JAPANESE CIRCULATION JOURNAL, 77(4), 1073-1080, 20130325
  173. Endothelial dysfunction : its pathology and methods to evaluate endothelial function, 35(4), 131-140, 20121225
  174. Striking crosstalk of ROCK signaling with endothelial function, J Cardiol, 60(1), 1-6, 20120810
  175. Hypertension and Endothelial Function : Is Endothelial Dysfunction Reversible in Essential hypertension?, Circulation journal : official journal of the Japanese Circulation Society, 66(0), 20020331
  176. Effect of Sildenafil Citrate on Endothelial Function in Healthy Young Men, Circulation journal : official journal of the Japanese Circulation Society, 66(0), 20020331
  177. FRS-066 Activated Rho-Kinase in Forearm Vascular Smooth Muscle Cells Contributes to Aortic Stiffness in Human(Atherosclerosis (IHD) : FRS8)(Featured Research Session (English)), Circulation journal : official journal of the Japanese Circulation Society, 68(0), 20040301
  178. FRS-136 Aging Activates Rho-Kinase in Smooth Muscle Cells of Forearm Vasculature in Humans(Gender and Geriatric Medicine and Risk Factors (H) : FRS17)(Featured Research Session (English)), Circulation journal : official journal of the Japanese Circulation Society, 68(0), 20040301
  179. OJ-421 Late phase of Ischemic Preconditioning Augment the Endothelium-Dependent Vasodilation on Human Forearm(Endothelium/NO 5 (H) : OJ51)(Oral Presentation (Japanese)), Circulation journal : official journal of the Japanese Circulation Society, 68(0), 20040301
  180. OJ-423 Nicorandil-Induced Vasodilation is, at Least in Part, due to Endothelium-Derived Hyperpolarizing Factor (EDHF) in Forearm Circulation in Humans(Endothelium/NO 5 (H) : OJ51)(Oral Presentation (Japanese)), Circulation journal : official journal of the Japanese Circulation Society, 68(0), 20040301
  181. PE-041 Is coronary microvascular dysfunction present in patients with vasospastic angina?(Nuclear Cardiology 5 (I) : PE7)(Poster Session (English)), Circulation journal : official journal of the Japanese Circulation Society, 68(0), 20040301
  182. PE-250 Smoking, Endothelial Function and Rho-Kinase in Smooth Muscle Cells of Forearm Vasculature in Healthy Young Humans(Smoking 1 (H) : PE43)(Poster Session (English)), Circulation journal : official journal of the Japanese Circulation Society, 68(0), 20040301
  183. PJ-342 Does flow-mediated dilation of the brachial artery correlate with coronary endothelial function?(Peripheral Circulation/Vascular Disease 3(H) : PJ57)(Poster Session (Japanese)), Circulation journal : official journal of the Japanese Circulation Society, 68(0), 20040301
  184. Hypertension and Endothelial Function : Role of Angiotensin II and Mechanical Pressure in Oxidative Stress, Circulation journal : official journal of the Japanese Circulation Society, 67(0), 20030301
  185. Safety and Feasibility of Bone Marrow Mononuclear Cells Transplantation in Patients with Peripheral Arterial Disease : Two-Year Follow Up Study(Angiogenesis 2 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 69(0), 20050301
  186. Is C-Reactive Protein Concentration Elevated in Patients with Any Kind of Coronary Artery Disease?(Nuclear Cardiology 8 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 69(0), 20050301
  187. Tetrahydrobioptrerin Augments Aging-related Impairment of Endothelial Function Through the Increase in NO Production and Decrease in Reactive Oxygen Species (Endothelium/NO 3 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 69(0), 20050301
  188. Autologous Bone Marrow Mononuclear Cell Implantation Induces Angiogenesis and Bone Regeneration in a Patient With Compartment Syndrome, Circulation journal : official journal of the Japanese Circulation Society, 70(10), 1362-1364, 20060920
  189. FRS-106 Pioglitazone Improves Endothelial Function in Essential Hypertensive Patients with Impaired Glucose Tolerance(Progress in Preventive Medicine-2 (H) FRS22,Featured Research Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 70(0), 139-140, 20060301
  190. OJ-166 Geranylgeranylacetone, A Heat Shock Protein 90 Inducer, Augments Endothel Function in Humans though an Increases in NO Production(Endothelium-2 (H) OJ28,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 70(0), 275-276, 20060301
  191. PE-377 Pycnogenol, French Maritime Pine Bark Extract, Augments Endothelium-dependent Vasodilation in Humans(Endothelium-3 (H) PE63,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 70(0), 20060301
  192. PE-438 Impact of the Metabolic Syndrome on Coronary Microvascular Endothelial Function(Diabetes/Obesity/Metabolic syndrome-4 (H) PE73,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 70(0), 20060301
  193. PE-527 Does Amount of Alcohol Consumption Contribute to Coronary Endothelial Function?(Preventive medicine/Epidemiology/Education-3 (H) PE89,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 70(0), 20060301
  194. PJ-051 Carvedilol Improves Endothelium-Dependent Vasodilation in Patients with Dilated Cardiomyopathy(Heart failure, clinical-17 (M) PJ9,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 70(0), 20060301
  195. PJ-389 The Effects of Different Intensities of Acute Exercise on Systemic and Forearm Hemodynamics in Humans : Role of Nitric Oxide(Exercise test/Cardiac rehabilitation-3 (IHD) PJ66,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 70(0), 20060301
  196. PJ-488 Relationship between Circulating Endothelial Progenitor Cells and Cardiovascular Risk(Atherosclerosis, clinical-12 (H) PJ82,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 70(0), 20060301
  197. PJ-754 Acute Administration of Caffeine Augments Endothelium-Dependent Vasodilation in Humans through an Increase in Nitric Oxide Production(Endothelium-6 (H) PJ130,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 70(0), 20060301
  198. Measurement of Flow-Mediated Vasodilation of the Brachial Artery : A Comparison of Measurements in the Seated and Supine Positions, Circulation journal : official journal of the Japanese Circulation Society, 71(5), 736-740, 20070420
  199. Estimating Arterial Wall Impedance Using a Strain-gauge Plethysmogram, Transactions of the Japanese Society for Medical and Biological Engineering : BME, 45(1), 55-62, 20070310
  200. 1 Method for Assessing Endothelial Function in Humans : A Strain-Gauge Plethysmography(Clinical Evaluation and Application of Endothelial Function, The 71st Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 71(0), 20070301
  201. PE-423 Pioglitazone Improves Endothelial Function in Hypertensive Patients with Impaired Glucose Tolerance : Role of Akt/eNOS/NO Pathway(Endothelium-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 71(0), 20070301
  202. PE-544 Flow-Mediated Vasodilation of Brachial Artery in Thromboangitis Obliterans (Buerger's Disease) : Role of Endothelial Progenitor Cells(Peripheral circulation/Vascular disease-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 71(0), 20070301
  203. PJ-452 Assessment of Coronary Microvascular Endothelial Function Using the Framingham Risk Score(Coronary circulation, basic/clinical-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 71(0), 584-585, 20070301
  204. PJ-456 Does Aspirin Improve Coronary Endothelial Function?(Coronary circulation, basic/clinical-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 71(0), 20070301
  205. PJ-703 Impact of the Presence of a Depressive State on Endothelial Dysfunction in Patients with Coronary Artery Disease(Preventive medicine/Epidemiology/Education-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 71(0), 20070301
  206. PJ-787 Geranylgeranylacetone Improves Endothelium-Dependent Vasodilation in Forearm Circulation in Smokers though an Increases in NO Production(Endothelium-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 71(0), 20070301
  207. FRS-039 Endothelial Function in Thromboangitis Obliterans (Buerger's Disease) : Role of Endothelial Progenitor Cells(Peripheral Vascular Disease(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 72(0), 151-152, 20080301
  208. FRS-058 Pioglitazone Improves Endothelial Function in Hypertensive Patients with Impaired Glucose Tolerance : Role of AMPK-eNOS pathway(New Insights into Metabolic Syndrome(02)(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 72(0), 20080301
  209. OE-265 Low-intensity Pulsed Ultrasound (LIPUS) Induces Angiogenesis in a Rat lschemic Hind Limb Model : Role of VEGF(Peripheral circulation/Vascular disease(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 72(0), 20080301
  210. OE-329 Periodontitis is Associated with Endothelial Dysfunction in Healthy Subjects as Well as Hypertensive Patients(Hypertension, clinical(02)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 72(0), 20080301
  211. OJ-205 Aging and Hypertension Are Independent Risk Factors for Reduced Number of Circulating Endothelial Progenitor Cells(Hypertension, clinical(03)(H),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 72(0), 20080301
  212. PE-118 Autologous Bone-Marrow Mesenchymal Stem Cell Implantation Induces Angiogenesis and Improves Endothelial Function in a Rabbit Ischemic Limb Model(Peripheral circulation/Vascular disease(03)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 72(0), 20080301
  213. PE-160 Smoking Abolishes Ischemic Preconditioning-induced Augmentation of Endothelium-Dependent Vasodilation : Role of Endothelium-Derived Nitric Oxide and Endothelial Progenitor Cells(Atherosclerosis, clinical(05)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 72(0), 20080301
  214. PE-212 Oral Infection-Inflammatory Pathway, Periodontitis, is a Risk Factor for Endothelial Dysfunction in Humans(Infection/Inflammation/Immunity(02)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 72(0), 20080301
  215. PE-503 Relationship between the Number of Circulating Endothelial Progenitor Cells and Medical History of Cardiovascular Diseases(Atherosclerosis, clinical(08)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 72(0), 20080301
  216. PJ-367 Does Depression Influence Endothelial Function More Strongly in Men or in Women with Coronary Artery Disease?(Preventive medicine/Epidemiology/Education(06)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 72(0), 603-604, 20080301
  217. PJ-532 Impact of the Presence of Chronic kidney Disease on Endothelial Function in Patients with Coronary Artery Disease(Kidney/Renal circulation(07)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 72(0), 20080301
  218. PJ-553 Classification of Corkscrew Collaterals in Thromboangitis Obliterans (Buerger's Disease) Using an Ultrasonography(Peripheral circulation/Vascular disease(08)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 72(0), 20080301
  219. PJ-731 Can the Angiographic Severity of Coronary Artery Disease Be Indetified Using Transient Ischemic Left Ventricular Dilation?(Nuclear cardiology(10)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 72(0), 20080301
  220. Endothelial Function and Oxidative Stress in Cardiovascular Diseases, Circulation journal : official journal of the Japanese Circulation Society, 73(3), 411-418, 20090220
  221. OE-175 Low-intensity Pulsed Ultrasound (LIPUS) Enhanced Angiogenesis in a Rat Hind Limb Ischemia Model, VEGF-A Expression and Mobilization in HUVEC(OE30,Preventive Medicine/Epidemiology/Education (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 73(0), 20090301
  222. OE-340 Rho Kinase Activity is Associated with Left Ventricular Hypertrophy in Hypertensive Patients(OE58,Hypertension, Clinical 2 (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 73(0), 20090301
  223. OE-391 Increased Leukocyte Rho Kinase (ROCK) Activity and Endothelial Dysfunction in Cigarette Smokers(OE66,Atherosclerosis (Clinical/Pathophysiology) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 73(0), 20090301
  224. PE-153 Activation of Rho Kinase (ROCK) Leads to Left Ventricular Diastolic Function in Patients with Essential Hypertension(PE026,Cardiac Function (Clinical) 1 (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 73(0), 20090301
  225. PE-424 Age and Baseline Vascular Brachial Artery Diameter are Independent Predictors of Flow-mediated Vasodilation in Healthy Subjects(PE071,Echo/Doppler (Peripheral/Vascular) (I),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 73(0), 20090301
  226. PJ-217 Impact of Chronic Kidney Disease on Myocardial Ischemia(PJ037,Nuclear Cardiology (Coronary, Myocardium) 1 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 73(0), 20090301
  227. PJ-442 A Combination Tablet of Losartan/Hydrochlorothiazide, PREMINENT[○!R], Improves Endothelial Function in Patients with Essential Hypertension(PJ075,Hypertension, Clinical 1 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 73(0), 20090301
  228. PJ-494 Is Angiographically Proven Good Collateral Circulation Functionally Adequate? : Assessment of Myocardial Perfusion Imaging(PJ083,Nuclear Cardiology (Coronary, Myocardium) 3 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 73(0), 20090301
  229. PJ-517 Do not Miss the Presence of Deep Echo Attenuation without Calcification on Intravascular Ultrasound!(PJ087,Coronary Revascularization, PCI (Restenosis/Others) 2 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 73(0), 20090301
  230. PJ-665 Periodontitis, Oral Infection-Inflammatory Pathway, is a Risk Factor for Endothelial Dysfunction in Patients with Coronary Artery Disease(PJ112,Atherosclerosis (Clinical/Pathophysiology) 2 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 73(0), 20090301
  231. PJ-718 The Effect of Selective Mineralocorticoid Receptor Blocker Eplerenone on Endothelial Function in Patients with Essential Hypertension(PJ121,Hypertension, Clinical 2 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 73(0), 20090301
  232. PJ-723 ACE Inhibitor Imidapril versus ARB Valsaratan on Endothelial Function in Patients with Essential Hypertension(PJ121,Hypertension, Clinical 2 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 73(0), 20090301
  233. PJ-748 Smoking Decreases the Number of Endothelial Progenitor Cells in Healthy Subjects but not in Patients with Cardiovascular Diseases(PJ126,Smoking/Alcohol/Life Style (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Circulation journal : official journal of the Japanese Circulation Society, 73(0), 20090301
  234. PAD and Cell Therapy, Japanese journal of apheresis, 32(1), 62-67, 20130228
  235. Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease, Atheroscierosis, 206(2), 604-610, 200910
  236. Sarpogrelate Hydrochloride, a Selective 5-hydroxytryptamine(2A) Antagonist, Augments Autologous Bone Marrow Mononuclear Cell Implantation-induced Improvement in Endothelium-dependent Vasodilation in Patients With Critical Limb Ischemia, Journal of Cardiovascular Pharmacology, 55(1), 56-61, 201001
  237. Dietary Phosphorus Acutely Impairs Endothelial Function, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 20(7), 1504-1512, 2009
  238. Relationships Among Hyperuricemia, Metabolic Syndrome, and Endothelial Function, AMERICAN JOURNAL OF HYPERTENSION, 24(7), 770-774, 2011
  239. Autologous Bone-Marrow Mesenchymal Stem Cell Implantation and Endothelial Function in a Rabbit Ischemic Limb Model, PLoS ONE, 8(7), 20130704
  240. Reliability of measurement of endothelial function across multiple institutions and establishment of reference values in Japanese, Atherosclerosis, 242(2), 433-442, 201510
  241. Anti-Aging Medicine in Cardiovascular Disease, Anti-Aging Med, 7(5), 45-49, 2010
  242. Study Design of SEASON Registry Prospective Surveillance of Cardiovascular Events in Antiplatelet-Treated ArterioSclerosis Obliterans Patients in JapaN (SEASON):Prospective Surveillance of Cardiovascular Events in Antiplatelet-Treated ArterioSclerosis Obliterans Patients in JapaN (SEASON), Japanese Heart Journal, 51(5), 337-342, 2010
  243. Effect of Amlodipine and Cilazapril Treatment on Platelet Ca2+ Handling in Spontaneously Hypertensive Rats, International Heart Journal, 38(4), 569-569, 1997
  244. A Multicenter Study Design to Assess the Clinical Usefulness of Semi-Automatic Measurement of Flow-Mediated Vasodilatation of the Brachial Artery, Japanese Heart Journal, 53(3), 170-175, 2012
  245. Poor Oral Health, That Is, Decreased Frequency of Tooth Brushing, Is Associated With Endothelial Dysfunction, JAPANESE CIRCULATION JOURNAL, 78(4), 950-954, 2014
  246. Leptin Causes Nitric-Oxide Independent Coronary Artery Vasodilation in Humans., Hypertension Research, 26(2), 147-152, 2003
  247. Estimation of Arterial Viscoelastic Properties during the Flow-mediated Dilation Test, Transactions of the Society of Instrument and Control Engineers, 49(11), 1029-1036, 2013
  248. a, Program and Abstracts of Annual Meeting of the Japanese Society of Periodontology, 2011(0), 8-8, 2011
  249. Evaluation of Vascular Endothelial Function Based on Oscillometric Method, BME, 52(0), O-387-O-388, 2014
  250. Borderline Ankle-Brachial Index Value of 0.91–0.99 Is Associated With Endothelial Dysfunction, JAPANESE CIRCULATION JOURNAL, 78(7), 1740-1745, 2014
  251. Depletion of Uric Acid Due to SLC22A12 (URAT1) Loss-of-Function Mutation Causes Endothelial Dysfunction in Hypouricemia, JAPANESE CIRCULATION JOURNAL, 0(0), 2015
  252. Assessment of Endothelial Function:History, Methodological Aspects, and Clinical Perspectives, Japanese Heart Journal, 56(2), 125-134, 2015
  253. Aging and vascular function, Blood & Vessel, 26(3), 302-309, 2015
  254. Effect of a Low-Intensity Pulsed Ultrasound Device, SX-1001, on Clinical Symptoms in Buerger Disease With Limb Ischemia:A Multicenter, Double-Blind, Parallel Randomized Clinical Trial, Japanese Heart Journal, 0(0), 2015
  255. Treatment of hypertension with anti-aldosterone agent, 221(9), 787-792, 20070602
  256. Educational lecture for physicians anti-aging, clinical (circulation), The journal of the Hiroshima Medical Association, 61(2), 80-85, 2008
  257. Dyslipidemia, Japanese journal of clinical medicine, 67(0), 284-289, 200904
  258. Endothelial function, Japanese journal of clinical medicine, 67(0), 144-148, 200910
  259. Measurement of endothelial function, endothelium-dependent vasodilation (e.g., FMD, plethysmography), Respiration and circulation, 58(9), 871-878, 201009
  260. Renin-angiotensin system and endothelial dysfunction, 65(10), 2233-2239, 201010
  261. Latest noninvasive methods to evaluate atherosclerosis, 60(7), 1516-1523, 201107
  262. Biomarkers for thrombosis and embolism, 35(13), 1762-1767, 201112
  263. Mechanisms of impairment of endothelial cell, 70(9), 1519-1523, 201209
  264. Aerobic exercise and endothelial function, 72(2), 243-252, 201208
  265. Interrelationship between hypertension and heart failure, 77(1), 36-40, 201501
  266. Vascular function and metabolic disease, 78(3), 283-287, 201509
  267. Role of Angiotensin II-Related Oxidative Stress and Nitric Oxide in Endothelial Function in Hypertension, 43(2), 47-52, 20030225
  268. A combination of flow-mediated vasodilation combined with nitroglycerine-induced vasodilation is more useful for prediction of cardiovascular events., Hypertension, 67(5), 1045-1052
  269. Exercise is a double-edge sword for endothelial function., Hypertens Research, 39, 61-63
  270. Long-term effect of sitagliptin on endothelial function in type 2 diabetes: a-sub-analysis of the PROLOGUE study., Cardiovasc Diabetol, 15, 134-134
  271. Vascular function and intima-media thickness of a leg artery in peripheral artery disease: a comparison of Buerger disease and atherosclerotic peripheral artery disease., Journal of Atherosclerosis and Thrombosis, 23, 1261-1269
  272. Response to Letter to the Editor: Re: Differences in the risk of osteoporotic femur fractures among Japanese and white women as predicted by carotid artery calcification visualized on panoramic images., Oral Surg Oral Med Oral Pathol Oral Radiol, 122, 655-656
  273. Corkscrew Collaterals in Raynaud's Syndrome, BMJ Case Reports, bcr2016215841.
  274. Anti-platele drugs and endothelial function, J Atheroscler Thromb., 23, 1147-1149
  275. Mesenchymal stem cell-derived exosomes promote fracture healing in a mouse model., Stem Cells Transl Med, 5, 1620-1630
  276. Rationale and design of a multicenter randomized controlled study to evaluate the preventive effect of ipragliflozin on carotid atherosclerosis: the PROTECT study., Cardiovasc Diabetol, 15, 133-133
  277. Circulating level of pigment epithelium-derived factor is associated with vascular function and brachial artery intima-media thickness., Int J Cardiol., 225, 91-95
  278. Association between number of teeth present and mandibular cortical erosion in Japanese men and women aged 40 years and older: a cross-sectional study., Osteoporos Sarcopenia, 2, 250-255
  279. Linagliptin Ameliorates Methylglyoxal-Induced Peritoneal Fibrosis in Mice., PLoS One, 11, e0160993-e0160993

Publications such as books

  1. 1991, Enhanced rectal and nasal absorption of human epidermal growrg factor by combined use of the absorption promoter and the synthetic polymer in rats , Eur. J. Drug Metab. Pharmacokin.= special issue No. 111, 1991, 7
  2. 2015/-0, LEARN MORE 研究者インタビュー 体の中にテニスコートが6面!? 血管内皮機能を知れば,動脈硬化と骨粗鬆症がもっとわかる, O.li.v.e. : osteo lipid vascular & endocrinology : 骨代謝と生活習慣病の連関, 唐橋 ユミ;東 幸仁;山岸 昌一
  3. 2010/-1, RASと血管内皮機能障害, 最新医学, 東 幸仁
  4. 2006/-0, RASによる血管内皮機能障害を探る, Vascular medicine : journal of vascular medicine / 「Vascular medicine」編集委員会 編, 東 幸仁
  5. 2008, アンチエイジングの臨床(循環器), 広島医学, 東 幸仁
  6. 2007/-0/8-, 医学と医療の最前線 動脈硬化の第一段階としての血管内皮障害, 日本内科学会雑誌, 東 幸仁
  7. 2012/-0, 運動療法と血管内皮機能, 循環器内科 / 循環器内科編集委員会 編, 東 幸仁
  8. 2015/-0, 血管機能と代謝疾患, 循環器内科 = Cardioangiology / 循環器内科編集委員会 編, 東 幸仁
  9. 2013/-0, 血管内皮機能障害に対する運動刺激, 体育の科学 / 日本体育学会 編, 東 幸仁
  10. 2011, 血管内皮機能の役割, 日本臨床スポーツ医学会誌 / 日本臨床スポーツ医学会編集委員会 編, 東 幸仁
  11. 2011/-1, 血管内皮機能の役割, 臨床スポーツ医学, 東 幸仁
  12. 2012/-0, 血管内皮障害の機序, 日本臨床, 東 幸仁
  13. 2011/-1, 抗凝固・抗血小板とアンチエイジング(第3回)血小板と血管内皮機能, Anti-aging science : 脳心血管抗加齢研究会機関誌 / 脳心血管抗加齢研究会事務局 [編], 野間 玄督;東 幸仁
  14. 2007/-0/6-, 高血圧治療と抗アルドステロン薬, 医学のあゆみ, 東 幸仁
  15. 2015/-0, 高血圧と心不全, 循環器内科 / 循環器内科編集委員会 編, 野間 玄督;木原 康樹;東 幸仁
  16. 2007/-1, 高脂血症, 体育の科学 / 日本体育学会 編, 東 幸仁
  17. 2014, 高尿酸血症のメカニズム 血管代謝・動脈硬化の側面から, Cardio vascular contemporary, 東 幸仁
  18. 2006/;2/00, 骨髄間葉系幹細胞を用いた血管新生療法とその臨床応用 : 間葉系幹細胞バンク化の検討, [東幸仁], 東幸仁, 広島大学 [著];東, 幸仁;広島大学
  19. 2009/-0, 脂質異常症, 日本臨床, 東 幸仁
  20. 2009/-1, 心・血管機能調節系 血管内皮機能, 日本臨床, 東 幸仁
  21. 2010/-0, 心雑音, 診断と治療, 野間 玄督;東 幸仁
  22. 2010/-0, 徐脈と頻脈, 診断と治療, 野間 玄督;東 幸仁
  23. 2008/-0, 生活習慣病のための検査--検査値をどうみるか(第5回)血管内皮機能, Life style medicine : journal of life style medicine / 「Life style medicine」編集委員会 編, 東 幸仁
  24. 2011/-1, 糖尿病における血管内皮機能検査, 糖尿病, 東 幸仁
  25. 2011/-0, 動脈硬化の非侵襲的検査, 綜合臨床, 野間 玄督;東 幸仁
  26. 2010/-0, 内皮機能検査--血流依存性血管拡張反応(FMD,プレチスモグラフィーなど), 呼吸と循環, 東 幸仁
  27. 2011/-1, 分子マーカー, 救急医学, 野間 玄督;東 幸仁
  28. 2007, 閉経後日本人女性における体格指数と歯の喪失との関係--肥満女性において高骨密度は歯の喪失抑制にはたらくのか?, オステオポローシスジャパン : 日本骨粗鬆症学会雑誌, 田口 明;真田 光博;東 幸仁 他;東 幸仁
  29. 2003/;2/00, 閉塞性動脈硬化症・ビュルガー病に対する自家骨骨髄細胞移植 : 骨髄間葉系幹細胞急速増殖法の応用および新生血管での血管内皮機能評価, [東幸仁], 東幸仁, 広島大学 [著];東, 幸仁;広島大学
  30. 2013/-0, 慢性炎症と血管機能をみる, Vascular medicine : journal of vascular medicine / 「Vascular medicine」編集委員会 編, 東 幸仁
  31. 2002/-0, 有酸素運動が血管内皮機能へ及ぼす影響, 理学療法科学 / 理学療法科学学会 編, 後藤 力;東 幸仁;佐々木 正太 他;佐々木 正太
  32. 2003/-1/0-, 閉塞性動脈硬化症患者における血管内皮機能の評価(第82回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 真田 博明;末田 泰二郎;渡橋 和政;東 幸仁
  33. 1992/-0/7-, 右心 Ejection Fraction Computer (REF-1) を用いた右室駆出率の検討(日本循環器学会 第57回中国・四国地方会), Japanese circulation journal, 東 幸仁;榎木 俊彦;高岡 克寿;福山 慎二;小畠 真;斉藤 紀;山木 戸道郎
  34. 1995/-0/3-, P528 ヒト血小板における細胞内マグネシウム濃度および細胞内カルシウム濃度の血圧との関連性について, Japanese circulation journal, 平賀 裕之;吉村 光功;松浦 秀夫;小野 法久;東 幸仁;渡辺 光章;梶山 梧朗;大島 哲也
  35. 1996, Renal response to L-arginine in salt-sensitive patients with essential hypertension(食塩感受性本態性高血圧症患者におけるL-アルギニン投与による腎反応性), 東幸仁 [著];東幸仁
  36. 2007/-0/3-, ストレインゲージプレチスモグラムを利用した血管壁インピーダンスの推定(<特集>生体医工学シンポジウム2006), 生体医工学 : 日本エム・イー学会誌, 柴 建次;寺尾 譲;辻 敏夫;吉栖 正生;東 幸仁;西岡 健司
  37. 2003/-1/0-, 冠攣縮性狭心症患者においてATP負荷心筋シンチは正常か? : 冠攣縮誘発試験陰性者との比較(第82回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺島 宏樹;上田 健太郎;木村 祐之;三浦 史晴;平尾 秀和;茶山 一章;大島 哲也;東 幸仁;吉栖 正生
  38. 2007/-0/4-, 111)兄弟3人に静脈系血栓症を発症したAT III欠損症の1家系(第89回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 藤井 雄一;寺川 宏樹;西岡 健司;出井 尚美;端 孝樹;曽我 潤子;竹本 博明;新宮 哲司;東 幸仁;吉栖 正生;大島 哲也;茶山 一彰
  39. 1999/-0/3-, P411 エストロゲン補充が自律神経活動およびQT時間に及ぼす影響, Japanese circulation journal, 中野 由紀子;大島 哲也;小園 亮次;松本 敏幸;神辺 眞之;平尾 秀和;東 幸仁;佐々木 正太;山田 忠克;大上 泰生;村岡 裕司;山形 東吾;松浦 秀夫;梶山 梧朗
  40. 2006/-0/4-, 20)アルコール摂取と冠動脈内皮機能の関係(第87回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;曽我 潤子;三保 成正;田渕 久美子;上田 佳子;小田 登;尾木 浩;三好 美和;中野 由紀子;茶山 一彰;東 幸仁;吉栖 正雄;大島 哲也
  41. 1999/-1/0-, 99) Liddle diseaseの1例, Japanese circulation journal, 砂川 真由美;東 幸仁;佐々木 正太;石田 隆史;吉水 功憲;植田 篤;上田 智広;大上 泰生;栗栖 智;杉野 浩;中河 啓悟;松浦 秀夫;梶山 梧朗;大島 哲也;小園 亮次;石田 万里;松本 敏幸;中野 由紀子;神辺 眞之
  42. 1995/-0/6-, 105)治療困難であった両側性腎血管性高血圧症の一例(日本循環器学会第64回中国地方会), Japanese circulation journal, 西亀 知子;東 幸仁;渡辺 光章;吉村 光功;平賀 裕之;石田 隆史;石田 万里;小野 法久;山形 東吾;唐川 真二;松浦 秀夫;梶山 梧朗;大島 哲也
  43. 2007/-0/4-, 85)循環器疾患患者のおけるN端末pro BNP測定の有用性 : BNPとの比較(第89回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 奥原 宏一郎;寺川 宏樹;西岡 健司;出井 尚美;端 孝樹;藤井 雄一;曽我 潤子;竹本 博明;日域 大輔;渡 雄一郎;東 幸仁;小園 亮治;新宮 哲司;吉栖 正生;大島 哲也;茶山 一彰
  44. 2000/-0/3-, 0610 性周期により自律神経活動及びQT時間は変化するか : 心拍変動解析を用いた検討, Japanese circulation journal, 中野 由紀子;大島 哲也;松本 敏幸;石田 万理;小園 亮次;神辺 眞之;東 幸仁;中河 啓悟;大上 泰生;平尾 秀和;山田 忠克;三浦 史晴;村岡 祐司;山形 東吾;松浦 秀夫;梶山 梧郎
  45. 2005/-1/0-, 上腕動脈の血管拡張反応と脈波伝播速度との関連(第86回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;岡野 勝二;日高 貴之;竹本 博明;尾木 浩;三好 美和;中野 由紀子;茶山 一彰;東 幸仁;吉栖 正雄;大島 哲也
  46. 1999/-0/3-, P682 減量による降圧におけるインスリン感受性と自律神経機能の影響 : 心拍変動による検討, Japanese circulation journal, 中野 由紀子;大島 哲也;小園 亮次;松本 敏幸;神辺 眞之;佐々木 正太;東 幸仁;植田 篤;吉水 功憲;栗栖 智;松浦 秀夫;梶山 梧朗
  47. 2004/-0/3-, 高血圧と血管内皮機能 : 酸化ストレスにおけるアンジオテンシンIIとメカニカルストレスの関与について(1. 高血圧性心血管病の成因・治療・予防 : 進歩と課題)(<特集II> : 第67回日本循環器学会学術集会), 循環器専門医 : 日本循環器学会専門医誌, 東 幸仁;吉栖 正生
  48. 2008/-0/4-, 35) 冠動脈疾患患者におけるCKDの血管内皮機能に及ぼす影響(第91回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;西岡 健司;藤村 憲崇;光波 直也;槙田 祐子;曽我 潤子;渡 雄一郎;藤井 雄一;奥原 宏一郎;新宮 哲司;東 幸仁;吉栖 正雄;茶山 一彰
  49. 2004/-1/0-, 20) TIMI frame countを用いて冠血流予備能の評価が可能か?(第84回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;木村 祐之;岡野 勝二;竹中 創;三浦 史晴;中野 由紀子;新宮 哲司;茶山 一彰;東 幸仁;吉栖 正雄;大島 哲也
  50. 1993/-0/8-, 急性心不全を発症した左右冠動脈左室瘻の1例 : 日本循環器学会第58回中国・四国地方会, Japanese circulation journal, 東 幸仁;福山 慎二;榎木 俊彦;高岡 克寿;小畠 真;斎藤 紀
  51. 2003/-1/0-, Sildenafil(Viagra^R)はsmokerの血管内皮機能異常を改善する : 内因性一酸化窒素(NO)の役割(第82回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 木村 祐之;日域 大輔;原 佳子;野間 玄督;中河 啓悟;東 幸仁;吉栖 正雄
  52. 2003/-1/0-, 冠動脈疾患患者における高感度C-reactive protein(CRP)の再現性(第82回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;木村 祐之;三浦 史晴;寺尾 秀和;茶山 一彰;大島 哲也;東 幸仁;吉栖 正生
  53. 2000/-0/3-, P362 心拍変動スペクトル解析とカプトプリル負荷試験を組み合わせた腎血管性高血圧症の診断, Japanese circulation journal, 中野 由紀子;大島 哲也;松本 敏幸;石田 万里;小園 亮次;神辺 眞之;東 幸仁;石田 隆史;石岡 規生;佐々木 正太;植田 篤;大上 泰生;杉野 浩;上田 智広;中河 啓悟;松浦 秀夫;梶山 梧朗
  54. 1999/-1/0-, 98) 血漿ノルエピネフリン(NE)高値にも関わらず高血圧を呈しなかった褐色細胞腫の一例, Japanese circulation journal, 木戸 和枝;佐々木 正太;東 幸仁;石田 隆史;植田 篤;吉水 功憲;上田 智広;大上 泰生;栗栖 智;杉野 浩;中河 啓悟;松浦 秀夫;梶山 梧朗;大島 哲也;小園 亮次;石田 万里;松本 敏幸;中野 由紀子;神辺 眞之
  55. 2013/-0/2-, PADと細胞移植(<特集>動脈硬化とアフェレシス), 日本アフェレシス学会雑誌, 東 幸仁
  56. 1998/-0/2-, P758 DipperおよびNon-dipper型本態性高血圧患者における自律神経活動の相違, Japanese circulation journal, 中野 由紀子;大島 哲也;小園 亮次;松本 敏幸;神辺 眞之;東 幸仁;佐々木 伸夫;佐々木 正太;植田 篤;吉水 功憲;栗栖 智;松浦 秀夫;梶山 梧朗
  57. 1994/-0/3-, 本態性高血圧症患者と健常者の食塩抵抗性の機序の差について : 第58回日本循環器学会学術集会, Japanese circulation journal, 大島 哲也;東 幸仁;小園 亮次;平賀 裕之;石田 隆史;石田 万里;渡辺 光章;吉村 光功;小野 法久;中崎 育明;松浦 秀夫;梶山 梧朗
  58. 2003/-0/4-, 16)冠動脈疾患患者における炎症反応と血管内皮機能の関係, Circulation journal : official journal of the Japanese Circulation Society, 寺田 宏樹;松田 圭司;上田 健太郎;木村 祐之;三浦 史晴;平尾 秀和;大島 哲也;東 幸仁;吉栖 正生
  59. 2005/-0/4-, 1177 運動強度の違いが酸化ストレスに与える影響(内部障害系理学療法11), 理学療法学, 後藤 力;東 幸仁;西岡 健司;日域 大輔;梅村 隆史;上田 佳子;吉栖 正生
  60. 1996/-0/2-, 0541 腎機能障害を有する高血圧症患者の内皮依存性腎血管拡張作用 : 正常血圧者および軽症本態性高血圧症患者との比較, Japanese circulation journal, 東 幸仁;石岡 規生;佐々木 伸夫;小野 法久;平賀 裕之;吉村 光功;渡辺 光章;松浦 秀夫;梶山 梧朗;中野 由紀子;大島 哲也
  61. 1997/-0/3-, 0995 食塩負荷は食塩感受性本態性高血圧患者の夜間降圧を抑制しnon-dipper typeの頻度を増加させる, Japanese circulation journal, 東 幸仁;佐々木 正太;井上 敏明;吉水 功憲;石岡 規生;佐々木 伸夫;吉村 光功;石橋 克彦;松浦 秀夫;梶山 梧朗;松本 敏幸;中野 由紀子;小園 亮次;大島 哲也
  62. 2007/-1/0-, 150)胸部症状の安定していた冠攣縮性狭心症患者の上顎洞術後に生じた重症冠攣縮(第90回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;西岡 健司;藤井 雄一;出井 尚美;端 孝樹;奥原 宏一郎;渡 雄一郎;久留島 秀治;荘川 知己;東 幸仁;吉栖 正生;大島 哲也;茶山 一彰
  63. 2001/-0/4-, 298 有酸素運動が血管内皮機能に及ぼす影響, 理学療法学, 後藤 力;東 幸仁;佐々木 正太;中河 啓悟;河村 光俊;奈良 勲
  64. 1995/-0/6-, 103)特発性アルドステロン症の一例(日本循環器学会第64回中国地方会), Japanese circulation journal, 藤高 一慶;渡辺 光章;東 幸仁;吉村 光功;平賀 裕之;石田 隆史;石田 万里;小野 法久;山形 東吾;唐川 真二;松浦 秀夫;梶山 梧朗;大島 哲也
  65. 1994/-0/3-, Deoxycorticoster one acetate(DOCA)食塩高血圧ラットにおける血小板Ca^<2+>動態とNa^+濃度 : 第58回日本循環器学会学術集会, Japanese circulation journal, 石田 万里;松浦 秀夫;石田 隆史;小園 亮次;小野 法久;吉村 光功;平賀 裕之;東 幸仁;渡辺 光章;中崎 育明;梶山 梧朗;大島 哲也
  66. 2004/-0/4-, 96) 上腕動脈の血流依存性拡張反応は冠動脈内皮機能と相関するか?(第83回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;木村 祐之;岡野 勝二;西岡 健司;竹中 創;三浦 史晴;中野 由紀子;茶山 一彰;東 幸仁;吉栖 正生
  67. 2006/-0/4-, 50)ステント内の器質化血栓をIntegrated Backscatter Intravascular Ultrasoundにて評価した急性冠症候群の1例(第87回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;曽我 潤子;三保 成正;上田 佳子;田渕 久美子;小田 登;尾木 浩;三好 美和;中野 由紀子;茶山 一彰;西岡 健司;東 幸仁;吉栖 正雄;大島 哲也
  68. 2002/-0/4-, 運動強度の違いが血管内皮機能に及ぼす影響(運動・神経生理), 理学療法学, 後藤 力;東 幸仁;中河 啓吾;木村 祐之;野間 玄督;原 佳子;佐々木 正太;茶山 一彰;河村 光俊;奈良 勲
  69. 2000/-0/4-, 182) レプチンはヒト末梢血管を拡張する, Japanese circulation journal, 中河 啓悟;東 幸仁;佐々木 正太;大島 哲也;松浦 秀夫;梶山 梧朗
  70. 1999/-0/3-, 0088 ヒト心筋細胞のアンジオテンシン2タイプ2受容体(AT2)蛋白の発現は心機能と相関する。 : 免疫学的検討, Japanese circulation journal, 松本 敏幸;小園 亮次;中野 由紀子;石田 万里;大島 哲也;中河 啓悟;上田 智広;大上 泰生;杉野 浩;栗栖 智;植田 篤;佐々木 正太;吉水 功憲;東 幸仁;石田 隆史;松浦 秀夫;梶山 梧朗;末田 泰二郎;松浦 雄一郎
  71. 2006/-1/0-, 242)Framingham risk scoreと冠動脈内皮機能の関係(第88回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;曽我 潤子;西岡 健司;日域 大輔;三保 成正;梅村 隆史;東 幸仁;吉栖 正雄;大島 哲也;茶山 一彰
  72. 2007/-1/0-, 123)心室中隔欠損症手術後シャント残存症例に発症した感染性心内膜炎(第90回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 藤井 雄一;寺川 宏樹;西岡 健司;出井 尚美;端 孝樹;奥原 宏一郎;渡 雄一郎;東 幸仁;吉栖 正生;小園 亮次;大島 哲也;茶山 一彰
  73. 2006/-1/0-, 246)思いがけず冠攣縮誘発試験がその診断に有用であった2症例(第88回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 曽我 潤子;寺川 宏樹;上田 健太郎;西岡 健司;日域 大輔;三保 成正;中田 篤範;中野 由紀子;東 幸仁;吉栖 正雄;大島 哲也;茶山 一彰
  74. 2008/-0/4-, 76) 臨床的にその合併を考えなかったものの心筋生検にて確定診断を得た心アミロイドーシスの1例(第91回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 渡邊 紀晶;寺川 宏樹;西岡 健司;光波 直也;藤村 憲崇;槙田 祐子;新宮 哲司;東 幸仁;吉栖 正雄;茶山 一彰

Invited Lecture, Oral Presentation, Poster Presentation

  1. Uric Acid and Endothelial Function: Role of Oxidative Stress., Yukihito Higashi, The 17th International Vascular Biology Meeting, 2014/04, With Invitation, Kyoto
  2. Gidelines for Non-invasive Vascular Function Test (JCS 2013): Endothelial Function., Yukihito Higashi, The 11th Pulse of Asia, 2014/06, With Invitation, Athena, Greece
  3. Regulation of eNOS mRNA destabilization via ROCK2-mediated eEF1A1 phosphorylation, Kensuke Noma, James K Liao, Yasuki Kihara, Yukihito Higashi, 19th World Congress on Heart Disease. International Academy of Cardiology Annual Scientific Sessions 201, 2014/07, With Invitation, Boston, MA, USA
  4. Relationships between Nitroglycerine-induced Vasodilation in the Brachial Artery and Cardiovascular Risk Factors., Tatsuya Maruhashi, Nozomu Oda, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yumiko Iwamoto, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara, Yukihito Higashi., The 11th Pulse of Asia 2014, 2014/06, Without Invitation, Athena, Greece
  5. Impact of Aldosterone Producing Adenoma on Endothelial Function in Patients With Primary Aldosteronism., Takeshi Matsumoto, Nozomu Oda, Akimichi Iwamoto, Yumiko Iwamoto, Masato Kajikawa, Tatsuya Maruhashi, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara, Yukihito Higashi., The 11th Pulse of Asia, 2014/06, Without Invitation, Athena, Greece
  6. Combination of Flow-mediated Vasodilation and Nitroglycerine-induced Vasodilation for Prediction of Cardiovascular Events., Masato Kajikawa, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi iwamoto, Takeshi Matsumoto, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara, Yukihito Higashi., The 11th Pluse of Asia, 2014/06, Without Invitation, Athena, Greece
  7. A Comparison of Nitroglycerine-induced Vasodilation with Flow-mediated Vasodilation as a Cardiovascular Risk Marker., Tatsuya Maruhashi, Nozomu Oda, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yumiko Iwamoto, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara, Yukihito Higashi., European Society of Cardiology Congress 2014, 2014/09, Without Invitation, Barcelona
  8. Endothelial Function Is Impaired in Subjects with Decreased Frequency of Tooth Brushing., Masato Kajikawa, Yukihito Higashi, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi iwamoto, Takeshi Matsumoto, Nozomu Oda, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara., 87th Scientific Sessions, American Heart Association, 2014/11, Without Invitation, Chicago, IL.
  9. Prognostic Value of Combination of Flow-mediated Vasodilation and Nitroglycerine-induced Vasodilation., Masato Kajikawa, Yukihito Higashi, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi iwamoto, Takeshi Matsumoto, Nozomu Oda, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara., 87th Scientific Sessions, American Heart Association, 2014/11, Without Invitation, Chicago, IL.
  10. Endothelial Function Is Impaired in Peripheral Arterial Disease with Borderline Ankle-Brachial Index., Masato Kajikawa, Yukihito Higashi, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi iwamoto, Takeshi Matsumoto, Nozomu Oda, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara., 87th Scientific Sessions, American Heart Association, 2014/11, Without Invitation
  11. Nitroglycerine-induced Vasodilation was Significantly Impaired in Peripheral Artery Disease-patients with Critical Limb Ischemia Compared with Those without., Tatsuya Maruhashi, Yukihito Higashi, Nozomu Oda, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yumiko Iwamoto, Ayumu Nakashima, Takayuki Hidaka, Kensuke Noma, Yasuki Kihara., 87th Scientific Sessions, American Heart Association, 2014/11, Without Invitation, Chicago, IL.
  12. Therapeutic Angiogenesis and Endothelial Function in Patients with Peripheral Artery Disease., 2014/03, With Invitation
  13. ROCK Activity and Endothelial Function: Potential Candidates for Vascular and Anti-aging Biomarkers, 2014/06, With Invitation
  14. Clinical Impact of ROCK in Sustained Vasoconstriction in Patients with Essential Hypertension., Kensuke Noma, Chikara Goto, Yasuki Kihara, Yukihito Higashi., 2014/07, With Invitation
  15. Six months follow-up of cardiovascular events in patients with ASO treated with antiplatelet agents: Interim report from SEASON., Yukihito Higashi, Tetsuro Miyata, Hiroshi Shigematsu, Hideki Origasa, Masatoshi Fujita, Hiroshi Matsuo, Hiroaki Naritomi, Hiroaki Matsuda., 2014/03, With Invitation
  16. Nitroglycerine-induced Vasodilation in the Brachial Artery and Cardiovascular Risk Factors., Tatsuya Maruhashi, Yukihito Higashi, Nozomu Oda, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yumiko Iwamoto, Ayumu Nakashima, Takayuki Hidaka, Kensuke Noma, Yasuki Kihara., 2014/03, Without Invitation
  17. ROCK as a Modulator of Sustained Vasoconstriction of ResistanceArtery in Patients with Essential Hypertension., Kensuke Noma, Chikara Goto, Yasuki Kihara, James K Liao, Yukihito Higashi., 2014/03, Without Invitation
  18. Difference Between Nitroglycerine-induced Vasodilation and Flow-mediated Vasodilation in Association with the Severity of Atherosclerosis., Tatsuya Maruhashi, Yukihito Higashi, Nozomu Oda, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yumiko Iwamoto, Ayumu Nakashima, Takayuki Hidaka, Kensuke Noma, Yasuki Kihara., 2014/03, Without Invitation
  19. Poor Oral Health Behavior is Associated with Endothelial Dysfunction., Masato Kajikawa, Yukihito Higashi, Kensuke Noma, Takayuki Hidaka, Ayumu Nakashima, Shinsuke Mikami, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi Iwamoto, Yasuki Kihara., 2014/03, Without Invitation
  20. Rho-Associated Kinase Activity and Risk of Cardiovascular Events., Masato Kajikawa, Yukihito Higashi, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi iwamoto, Takeshi Matsumoto, Takayuki Hidaka, Ayumu Nakashima, James K. Liao, Kensuke Noma, Yasuki Kihara., 2014/03, Without Invitation
  21. Role of ROCK in Sustained Arterial Vasoconstriction in Patients with Essential Hypertension., Kensuke Noma, Chikara Goto, Yasuki Kihara, James K Liao, Yukihito Higashi., The 18th International Vascular Biology Meeting (IVBM 2014), 2014/04, Without Invitation
  22. Destabilization of eNOS mRNA via ROCK2-mediated eEF1A1 phosphorylation., 2014/05, Without Invitation
  23. Regulation of eNOS mRNA stability vie ROCK2-mediated phosphorylation of eEF1A., 2014/02, Without Invitation
  24. Low Intensity Pulsed Ultrasound Induced Angiogenesis through Activation of Integrin Signaling in Endothelial Cells., 2014/02, Without Invitation
  25. Endothelial function and oxidative stress., Yukihito Higashi, The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide, 2016/05/22, With Invitation, The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide, Sendai
  26. Endothelial function and hypertension, Yukihito Higashi, The 6th Chinese Society of Hypertension, 2016/07/24, With Invitation, The 6th Chinese Society of Hypertension, Changchun
  27. Endothelial function, hypertension, and aging., Yukihito Higashi, Pulse of Asia, 2016/09/24, With Invitation, Pulse of Asia, Soul