Yukihito Higashi

Last Updated :2024/05/15

Affiliations, Positions
Research Institute for Radiation Biology and Medicine, Professor
E-mail
yhigashihiroshima-u.ac.jp
Other Contact Details
1-2-3　Kasumi Minami-ku Hiroshima, Japan
TEL : (+81)82-257-5831 FAX : (+81)

Basic Information

Major Professional Backgrounds

  • 2009/04/01, 2013/09/19, 広島大学病院再生医療部部長（併任）, 広島大学病院再生医療部部長（併任）
  • 2013/09/20, 広島大学病院未来医療センター長（併任）, 広島大学病院未来医療センター長（併任）

Educational Backgrounds

  • Hiroshima University, Faculty of Medicine, Japan, 1982/04, 1988/03

Academic Degrees

  • Medical Doctor, Hiroshima University

Educational Activity

  • [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine
  • [Master's Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences : Program of Biomedical Science
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences : Program of Biomedical Science
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Radiation Biology and Medicine

In Charge of Primary Major Programs

  • Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Boundary medicine;Laboratory medicine

Research Keywords

  • oxidative stress
  • myocradial regeneration
  • nitric oxide
  • angiogenesis
  • endothelial function
  • hypertension

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, Year, Clinical diagnosis and treatment I
  2. 2024, Undergraduate Education, Intensive, Practice for medical research
  3. 2024, Graduate Education (Master's Program) , First Semester, Seminar
  4. 2024, Graduate Education (Master's Program) , Second Semester, Seminar
  5. 2024, Graduate Education (Master's Program) , First Semester, Research
  6. 2024, Graduate Education (Master's Program) , Second Semester, Research
  7. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar
  8. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar
  9. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research
  10. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research
  11. 2024, Graduate Education (Master's Program) , Second Semester, Pathologic Basis of Diseases
  12. 2024, Graduate Education (Doctoral Program) , 1Term, Integrated Radiation Medical Science
  13. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Regenerative Medicine
  14. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Regenerative Medicine
  15. 2024, Graduate Education (Doctoral Program) , First Semester, Adcanced Research on Regenerative Medicine
  16. 2024, Graduate Education (Doctoral Program) , Second Semester, Adcanced Research on Regenerative Medicine

Research Activities

Academic Papers

  1. Effects of low-dose colchicine on serum high-sensitive C reactive protein level in coronary artery disease patients with type 2 diabetes mellitus and enhanced inflammatory response. Protocol for a randomized, double-blind, placebo-controlled, phase II, dose- finding study., Biomed Hub, 7(3), 156-164, 20221201
  2. ★, A good time to reconsider the associations of calcium and magnesium with hypertension., Circ J, 86(9), 1474-1475, 202208
  3. Effect of novel stratified lpid risk by "LDL-Window" and flow-mediated dilation on the prognosis of coronary artery disease using the FMD-J Study A data, Circ J., 86(9), 1444-1454, 202208
  4. ★, Reply to a letter to the editor regarding "Short stature is associated with low flow-mediated vasodilation in Japanese men", Hypertens Res., 45(7), 1221, 202207
  5. ★, Beneficial effects of supplementation on endothelial function: what mechanisms?, J Atheroscler Thromb, 29(9), 1268-1270, 202209
  6. ★, Clinical implication of impaired skin microvascular function in patients with hypertension., Hypertens Res, 45(3), 535-537, 202203
  7. ★, Effect of exposure to radiation caused by an atomic bomb on endothelial function in atomic bomb survivors, FRONTIERS IN CARDIOVASCULAR MEDICINE, 10, 20230217
    Link to Paper Search Results by DOI
  8. ★, Current topic of vascular function in hypertension, HYPERTENSION RESEARCH, 46(3), 630-637, 202303
    Link to Paper Search Results by DOI
  9. ★, Early-Phase Changes in Serum Free Fatty Acid Levels After Glucose Intake Are Associated With Type 2 Diabetes Incidence: The Hiroshima Study on Glucose Metabolism and Cardiovascular Diseases, DIABETES CARE, 45(10), 2309-2315, 202210
    Link to Paper Search Results by DOI
  10. ★, The prevalence of cardiovascular disease is higher in patients with bilateral low ankle-brachial index than in patients with unilateral low ankle-brachial index, ATHEROSCLEROSIS, 360, 8-14, 202211
    Link to Paper Search Results by DOI
  11. ★, Roles of Oxidative Stress and Inflammation in Vascular Endothelial Dysfunction-Related Disease, ANTIOXIDANTS, 11(10), 202210
    Link to Paper Search Results by DOI
  12. ★, Adipose tissue insulin resistance predicts the incidence of hypertension: The Hiroshima Study on Glucose Metabolism and Cardiovascular Diseases, HYPERTENSION RESEARCH, 45(11), 1763-1771, 202211
    Link to Paper Search Results by DOI
  13. ★, Serum Potassium Levels of 4.5 to Less Than 5.0 mmol/L Are Associated with Better Vascular Function, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 29(11), 1588-1602, 2022
    Link to Paper Search Results by DOI
  14. ★, Effectiveness of High-Intensity Interval Training and Continuous Moderate-Intensity Training on Blood Pressure in Physically Inactive Pre-Hypertensive Young Adults, JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE, 9(8), 202208
    Link to Paper Search Results by DOI
  15. ★, Promising Assessment of Vascular Function for Future Cardiovascular Events, J Atheroscler Thromb, 28(11), 1123-1125, 2021
  16. ★, Relationship of Daily Coffee Intake with Vascular Function in Patients with Hypertension, NUTRIENTS, 14(13), 202207
    Link to Paper Search Results by DOI
  17. ★, Cardiovascular risk in patients receiving antihypertensive drug treatment from the perspective of endothelial function, HYPERTENSION RESEARCH, 45(8), 1322-1333, 202208
    Link to Paper Search Results by DOI
  18. Update on Hypertension Research in 2021, HYPERTENSION RESEARCH, 45(8), 1276-1297, 202208
    Link to Paper Search Results by DOI
  19. ★, Obesity and Endothelial Function, BIOMEDICINES, 10(7), 202207
    Link to Paper Search Results by DOI
  20. ★, Temporal Changes in Sparing and Enhancing Dose Protraction Effects of Ionizing Irradiation for Aortic Damage in Wild-Type Mice, CANCERS, 14(14), 202207
    Link to Paper Search Results by DOI
  21. ★, White blood cell count is not associated with flow-mediated vasodilation or nitroglycerine-induced vasodilation, SCIENTIFIC REPORTS, 12(1), 20220517
    Link to Paper Search Results by DOI
  22. ★, Long-Term Effect of Febuxostat on Endothelial Function in Patients With Asymptomatic Hyperuricemia: A Sub-Analysis of the PRIZE Study, FRONTIERS IN CARDIOVASCULAR MEDICINE, 9, 20220428
    Link to Paper Search Results by DOI
  23. ★, Relationship between hemoglobin A1c level and flow-mediated vasodilation in patients with type 2 diabetes mellitus receiving antidiabetic drugs, JOURNAL OF DIABETES INVESTIGATION, 13(4), 677-686, 202204
    Link to Paper Search Results by DOI
  24. ★, Self-reported total sitting time on a non-working day is associated with blunted flow-mediated vasodilation and blunted nitroglycerine-induced vasodilation, SCIENTIFIC REPORTS, 12(1), 20220416
    Link to Paper Search Results by DOI
  25. ★, Implantation of Hypoxia-Induced Mesenchymal Stem Cell Advances Therapeutic Angiogenesis, STEM CELLS INTERNATIONAL, 2022, 20220320
    Link to Paper Search Results by DOI
  26. ★, Association of Flow Parameters and Diameter in the Common Carotid Artery with Impaired Glucose Metabolism, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 29(5), 654-666, 2022
    Link to Paper Search Results by DOI
  27. ★, Isolated diastolic hypertension is not associated with endothelial dysfunction, HYPERTENSION RESEARCH, 45(4), 698-707, 202204
    Link to Paper Search Results by DOI
  28. ★, Poor tooth brushing behavior is associated with high risk of cardiovascular events: A prospective observational study, INTERNATIONAL JOURNAL OF CARDIOLOGY, 350, 111-117, 20220301
    Link to Paper Search Results by DOI
  29. Annual reports on hypertension research 2020, HYPERTENSION RESEARCH, 45(1), 15-31, 202201
    Link to Paper Search Results by DOI
  30. ★, Association of obesity with serum free fatty acid levels in individuals at different stages of prediabetes, CLINICAL OBESITY, 12(1), 202202
    Link to Paper Search Results by DOI
  31. ★, Short stature is associated with low flow-mediated vasodilation in Japanese men, HYPERTENSION RESEARCH, 45(2), 308-314, 202202
    Link to Paper Search Results by DOI

Publications such as books

  1. 2019, Billrubin and endothelial function, J Atheroscler Thromb, 2019, 2019, Scholarly Book, Joint work, English, Maruhashi Tatsuya, Kihara Yasuki, Higashi Yukihito
  2. 2019, 臨床泌尿器科, 男性の百寿社会のために テストステロンの徹底理解. テストステロンと血管内皮機能., 医学書院, 2019, 1, Scholarly Book, Single work, 日本語, Higashi Yukihito
  3. 2019, DIABETES UPDATE, メディカルレビュー社, 2019, Scholarly Book, Single work, 日本語, Higashi Yukihito
  4. 2019, Heart View., メディカルレビュー社, 2019, Scholarly Book, Single work, 日本語, Higashi Yukihito
  5. 2018, 高尿酸血症・痛風の治療ガイドライン 第３版, 日本痛風・拡散代謝学会 ガイドライン改定委員会, 2018, 2018, Textbook, Joint work, Higashi Yukihito
  6. 2018, 文春クリニック　食の新常識, 文藝春秋（株）, 2018, 2018, Others, Single work, 日本語, Higashi Yukihito
  7. 2018, 「糖尿病」HbA1c・血糖値をピタッと下げるコツとワザ, 主婦の友インフォス（株）, 2018, 2018, Others, Single work, 日本語, Higashi Yukihito
  8. 2018, 「高齢者歯周治療学」Part 2.第2章 2-3 血管系の変化とその対策・治療上の注意点, インターアクション（株）, 2018, 2018, Others, Joint work, 日本語, Higashi Yukihito
  9. 2018/20/18, 「糖尿病」HbA1c・血糖値をピタッと下げるコツとワザ, 主婦の友インフォス（株）, 2018, 2018, Others, Joint work, 日本語, Higashi Yukihito
  10. 2018/20/18, 高尿酸血症・痛風の治療ガイドライン 第３版.ダイジェスト・ポケット版, 日本痛風・拡散代謝学会 ガイドライン改定委員会, 2018, 2018, Textbook, Joint work, 日本語, Higashi Yukihito
  11. 2018, Assessment of endothelium-independent vasodilation: from methodology to clinical perspectives, J Hypertens, 2018, 2018, Scholarly Book, Joint work, English, Maruhashi Tatsuya, Kihara Yasuki, Higashi Yukihito
  12. 2018, Hyperuricemia and endothelial function: from molecular background to clinical perspectives, Atherosclerosis, 2018, 2018, Scholarly Book, Joint work, English, Maruhashi Tatsuya, Hisatome Ichiro, Kihara Yasuki, Higashi Yukihito
  13. 2018, Physiological diagnosis criteria for vascular failure, Hypertension, 2018, 2018, Scholarly Book, Joint work, English, Tanaka Atsushi, Tomiyama Hirofumi, Maruhashi Tatsuya, Matsuzawa Yasushi, Miyoshi Toru, Kabutoya Tomiyuki, Kario Kazuomi, Sugiyama Seigo, Munakata Masanori, Ito Hiroshi, Higashi Yukihito, Inoue Teruo, Node Koichi
  14. 2018, Cilostazol for the treatment of cerebral infarction, Expert Opin Pharmacother, 2018, 2018, Scholarly Book, Joint work, English, Noma Kensuke, Higashi Yukihito
  15. 2018, Official Announcement of Physiological Diagnostic Criteria for Vascular Failure from the Japanese Society for Vascular Failure, Vasc Fail, 2018, 2018, Scholarly Book, Joint work, English, Tanaka Atsushi, Tomiyama Hirofumi, Maruhashi Tatsuya, Matsuzawa Yasushi, Miyoshi Toru, Kabutoya Tomoyuki, Kario Kazunori, Sugiyama Seigo, Munakata Masanori, Ito Hiroshi, Higashi Yukihito, Inoue Teruo, Node Koichi.
  16. 2018, 1.血管内皮細胞機能の臨床的評価, 血管内皮細胞機能を再考する, Thrombosis Medicine, 2018, 2018, Scholarly Book, Single work, 日本語, Higashi Yukihito
  17. 2018, 血圧・血管内皮細胞機能から見て. 糖尿病の最新治療, 糖尿病と動脈硬化Update, フジメディカル出版, 2018, 2018, Scholarly Book, Single work, 日本語, Higashi Yukihito, 5
  18. 2018, III.検査診断学の進歩. 5.血管内皮細胞機能評価, 血栓・塞栓症 -診断・治療・予防の最新動向-, 日本臨床, 2018, 2018, Textbook, Single work, 日本語, Higashi Yukihito, 7
  19. 2018, 循環器内科医, 高尿酸血症は心血管病のリスクか？, 科学評論社, 2018, Scholarly Book, Single work, 日本語, Higashi Yukihito
  20. 2018, 「脳心血管坑加齢研究会2018:日々是好日：脳心血管加齢を処方す」開催にあたって., 「脳心血管坑加齢研究会2018:日々是好日：脳心血管加齢を処方す」開催にあたって., Anti-aging Science., 2018, Scholarly Book, Single work, 日本語, Higashi Yukihito
  21. 2018, 循環器内科医が考える糖尿病治療 〜血管内皮機能〜, 循環器内科医が考える糖尿病治療 〜血管内皮機能〜, 山県郡医師会報, 2018, Scholarly Book, Single work, 日本語, Higashi Yukihito
  22. 2018, 研究最前線. 緊急被ばく医療における再生医療の確立と血管機能研究., 研究最前線. 緊急被ばく医療における再生医療の確立と血管機能研究., 広島大学広報誌BHS NEWS., 2018, Scholarly Book, Single work, 日本語, Higashi Yukihito
  23. 2017, Therapeutic Angiogenesis., Therapeutic Angiogenesis., Springer, 2017, 2017, Scholarly Book, Compilation, English, Editors: Yukihtio Hiagshi, Toyoaki Murohara
  24. 2016, NO, ADMA(asymmetric dimethylarginine), NO, ADMA(asymmetric dimethylarginine), 2016, Scholarly Book, Joint work, 日本語, Tatsuya Maruhashi, Yasuki Kihara, Yukihito Higashi, 7, 87-93
  25. 1991, Enhanced rectal and nasal absorption of human epidermal growrg factor by combined use of the absorption promoter and the synthetic polymer in rats , Eur. J. Drug Metab. Pharmacokin.= special issue No. 111, 1991, Scholarly Book, Joint work, 7
  26. 2015/05, LEARN MORE 研究者インタビュー 体の中にテニスコートが6面!? 血管内皮機能を知れば,動脈硬化と骨粗鬆症がもっとわかる, O.li.v.e. : osteo lipid vascular & endocrinology : 骨代謝と生活習慣病の連関, 唐橋 ユミ;東 幸仁;山岸 昌一
  27. 2010/10, RASと血管内皮機能障害, 最新医学, 東 幸仁
  28. 2006/01, RASによる血管内皮機能障害を探る, Vascular medicine : journal of vascular medicine / 「Vascular medicine」編集委員会 編, 東 幸仁
  29. 2008, アンチエイジングの臨床(循環器), 広島医学, 東 幸仁
  30. 2007/08/10, 医学と医療の最前線 動脈硬化の第一段階としての血管内皮障害, 日本内科学会雑誌, 東 幸仁
  31. 2012/08, 運動療法と血管内皮機能, 循環器内科 / 循環器内科編集委員会 編, 東 幸仁
  32. 2015/09, 血管機能と代謝疾患, 循環器内科 = Cardioangiology / 循環器内科編集委員会 編, 東 幸仁
  33. 2013/08, 血管内皮機能障害に対する運動刺激, 体育の科学 / 日本体育学会 編, 東 幸仁
  34. 2011, 血管内皮機能の役割, 日本臨床スポーツ医学会誌 / 日本臨床スポーツ医学会編集委員会 編, 東 幸仁
  35. 2011/12, 血管内皮機能の役割, 臨床スポーツ医学, 東 幸仁
  36. 2012/09, 血管内皮障害の機序, 日本臨床, 東 幸仁
  37. 2011/11, 抗凝固・抗血小板とアンチエイジング(第3回)血小板と血管内皮機能, Anti-aging science : 脳心血管抗加齢研究会機関誌 / 脳心血管抗加齢研究会事務局 [編], 野間 玄督;東 幸仁
  38. 2007/06/02, 高血圧治療と抗アルドステロン薬, 医学のあゆみ, 東 幸仁
  39. 2015/01, 高血圧と心不全, 循環器内科 / 循環器内科編集委員会 編, 野間 玄督;木原 康樹;東 幸仁
  40. 2007/12, 高脂血症, 体育の科学 / 日本体育学会 編, 東 幸仁
  41. 2014, 高尿酸血症のメカニズム 血管代謝・動脈硬化の側面から, Cardio vascular contemporary, 東 幸仁
  42. 2006, 骨髄間葉系幹細胞を用いた血管新生療法とその臨床応用 : 間葉系幹細胞バンク化の検討, [東幸仁], 東幸仁, 広島大学 [著];東, 幸仁;広島大学
  43. 2009/04, 脂質異常症, 日本臨床, 東 幸仁
  44. 2009/10, 心・血管機能調節系 血管内皮機能, 日本臨床, 東 幸仁
  45. 2010/03, 心雑音, 診断と治療, 野間 玄督;東 幸仁
  46. 2010/03, 徐脈と頻脈, 診断と治療, 野間 玄督;東 幸仁
  47. 2008/01, 生活習慣病のための検査--検査値をどうみるか(第5回)血管内皮機能, Life style medicine : journal of life style medicine / 「Life style medicine」編集委員会 編, 東 幸仁
  48. 2011/12, 糖尿病における血管内皮機能検査, 糖尿病, 東 幸仁
  49. 2011/07, 動脈硬化の非侵襲的検査, 綜合臨床, 野間 玄督;東 幸仁
  50. 2010/09, 内皮機能検査--血流依存性血管拡張反応(FMD,プレチスモグラフィーなど), 呼吸と循環, 東 幸仁
  51. 2011/12, 分子マーカー, 救急医学, 野間 玄督;東 幸仁
  52. 2007, 閉経後日本人女性における体格指数と歯の喪失との関係--肥満女性において高骨密度は歯の喪失抑制にはたらくのか?, オステオポローシスジャパン : 日本骨粗鬆症学会雑誌, 田口 明;真田 光博;東 幸仁 他;東 幸仁
  53. 2003, 閉塞性動脈硬化症・ビュルガー病に対する自家骨骨髄細胞移植 : 骨髄間葉系幹細胞急速増殖法の応用および新生血管での血管内皮機能評価, [東幸仁], 東幸仁, 広島大学 [著];東, 幸仁;広島大学
  54. 2013/04, 慢性炎症と血管機能をみる, Vascular medicine : journal of vascular medicine / 「Vascular medicine」編集委員会 編, 東 幸仁
  55. 2002/05, 有酸素運動が血管内皮機能へ及ぼす影響, 理学療法科学 / 理学療法科学学会 編, 後藤 力;東 幸仁;佐々木 正太 他;佐々木 正太
  56. 2003/10/20, 閉塞性動脈硬化症患者における血管内皮機能の評価(第82回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 真田 博明;末田 泰二郎;渡橋 和政;東 幸仁
  57. 1992/07/20, 右心 Ejection Fraction Computer (REF-1) を用いた右室駆出率の検討(日本循環器学会 第57回中国・四国地方会), Japanese circulation journal, 東 幸仁;榎木 俊彦;高岡 克寿;福山 慎二;小畠 真;斉藤 紀;山木 戸道郎
  58. 1995/03/01, P528 ヒト血小板における細胞内マグネシウム濃度および細胞内カルシウム濃度の血圧との関連性について, Japanese circulation journal, 平賀 裕之;吉村 光功;松浦 秀夫;小野 法久;東 幸仁;渡辺 光章;梶山 梧朗;大島 哲也
  59. 1996, Renal response to L-arginine in salt-sensitive patients with essential hypertension(食塩感受性本態性高血圧症患者におけるL-アルギニン投与による腎反応性), 東幸仁 [著];東幸仁
  60. 2007/03/10, ストレインゲージプレチスモグラムを利用した血管壁インピーダンスの推定(<特集>生体医工学シンポジウム2006), 生体医工学 : 日本エム・イー学会誌, 柴 建次;寺尾 譲;辻 敏夫;吉栖 正生;東 幸仁;西岡 健司
  61. 2003/10/20, 冠攣縮性狭心症患者においてATP負荷心筋シンチは正常か? : 冠攣縮誘発試験陰性者との比較(第82回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺島 宏樹;上田 健太郎;木村 祐之;三浦 史晴;平尾 秀和;茶山 一章;大島 哲也;東 幸仁;吉栖 正生
  62. 2007/04/20, 111)兄弟3人に静脈系血栓症を発症したAT III欠損症の1家系(第89回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 藤井 雄一;寺川 宏樹;西岡 健司;出井 尚美;端 孝樹;曽我 潤子;竹本 博明;新宮 哲司;東 幸仁;吉栖 正生;大島 哲也;茶山 一彰
  63. 1999/03/01, P411 エストロゲン補充が自律神経活動およびQT時間に及ぼす影響, Japanese circulation journal, 中野 由紀子;大島 哲也;小園 亮次;松本 敏幸;神辺 眞之;平尾 秀和;東 幸仁;佐々木 正太;山田 忠克;大上 泰生;村岡 裕司;山形 東吾;松浦 秀夫;梶山 梧朗
  64. 2006/04/20, 20)アルコール摂取と冠動脈内皮機能の関係(第87回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;曽我 潤子;三保 成正;田渕 久美子;上田 佳子;小田 登;尾木 浩;三好 美和;中野 由紀子;茶山 一彰;東 幸仁;吉栖 正雄;大島 哲也
  65. 1999/10/20, 99) Liddle diseaseの1例, Japanese circulation journal, 砂川 真由美;東 幸仁;佐々木 正太;石田 隆史;吉水 功憲;植田 篤;上田 智広;大上 泰生;栗栖 智;杉野 浩;中河 啓悟;松浦 秀夫;梶山 梧朗;大島 哲也;小園 亮次;石田 万里;松本 敏幸;中野 由紀子;神辺 眞之
  66. 1995/06/20, 105)治療困難であった両側性腎血管性高血圧症の一例(日本循環器学会第64回中国地方会), Japanese circulation journal, 西亀 知子;東 幸仁;渡辺 光章;吉村 光功;平賀 裕之;石田 隆史;石田 万里;小野 法久;山形 東吾;唐川 真二;松浦 秀夫;梶山 梧朗;大島 哲也
  67. 2007/04/20, 85)循環器疾患患者のおけるN端末pro BNP測定の有用性 : BNPとの比較(第89回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 奥原 宏一郎;寺川 宏樹;西岡 健司;出井 尚美;端 孝樹;藤井 雄一;曽我 潤子;竹本 博明;日域 大輔;渡 雄一郎;東 幸仁;小園 亮治;新宮 哲司;吉栖 正生;大島 哲也;茶山 一彰
  68. 2000/03/01, 0610 性周期により自律神経活動及びQT時間は変化するか : 心拍変動解析を用いた検討, Japanese circulation journal, 中野 由紀子;大島 哲也;松本 敏幸;石田 万理;小園 亮次;神辺 眞之;東 幸仁;中河 啓悟;大上 泰生;平尾 秀和;山田 忠克;三浦 史晴;村岡 祐司;山形 東吾;松浦 秀夫;梶山 梧郎
  69. 2005/10/20, 上腕動脈の血管拡張反応と脈波伝播速度との関連(第86回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;岡野 勝二;日高 貴之;竹本 博明;尾木 浩;三好 美和;中野 由紀子;茶山 一彰;東 幸仁;吉栖 正雄;大島 哲也
  70. 1999/03/01, P682 減量による降圧におけるインスリン感受性と自律神経機能の影響 : 心拍変動による検討, Japanese circulation journal, 中野 由紀子;大島 哲也;小園 亮次;松本 敏幸;神辺 眞之;佐々木 正太;東 幸仁;植田 篤;吉水 功憲;栗栖 智;松浦 秀夫;梶山 梧朗
  71. 2004/03/25, 高血圧と血管内皮機能 : 酸化ストレスにおけるアンジオテンシンIIとメカニカルストレスの関与について(1. 高血圧性心血管病の成因・治療・予防 : 進歩と課題)(<特集II> : 第67回日本循環器学会学術集会), 循環器専門医 : 日本循環器学会専門医誌, 東 幸仁;吉栖 正生
  72. 2008/04/20, 35) 冠動脈疾患患者におけるCKDの血管内皮機能に及ぼす影響(第91回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;西岡 健司;藤村 憲崇;光波 直也;槙田 祐子;曽我 潤子;渡 雄一郎;藤井 雄一;奥原 宏一郎;新宮 哲司;東 幸仁;吉栖 正雄;茶山 一彰
  73. 2004/10/20, 20) TIMI frame countを用いて冠血流予備能の評価が可能か?(第84回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;木村 祐之;岡野 勝二;竹中 創;三浦 史晴;中野 由紀子;新宮 哲司;茶山 一彰;東 幸仁;吉栖 正雄;大島 哲也
  74. 1993/08/20, 急性心不全を発症した左右冠動脈左室瘻の1例 : 日本循環器学会第58回中国・四国地方会, Japanese circulation journal, 東 幸仁;福山 慎二;榎木 俊彦;高岡 克寿;小畠 真;斎藤 紀
  75. 2003/10/20, Sildenafil(Viagra^R)はsmokerの血管内皮機能異常を改善する : 内因性一酸化窒素(NO)の役割(第82回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 木村 祐之;日域 大輔;原 佳子;野間 玄督;中河 啓悟;東 幸仁;吉栖 正雄
  76. 2003/10/20, 冠動脈疾患患者における高感度C-reactive protein(CRP)の再現性(第82回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;木村 祐之;三浦 史晴;寺尾 秀和;茶山 一彰;大島 哲也;東 幸仁;吉栖 正生
  77. 2000/03/01, P362 心拍変動スペクトル解析とカプトプリル負荷試験を組み合わせた腎血管性高血圧症の診断, Japanese circulation journal, 中野 由紀子;大島 哲也;松本 敏幸;石田 万里;小園 亮次;神辺 眞之;東 幸仁;石田 隆史;石岡 規生;佐々木 正太;植田 篤;大上 泰生;杉野 浩;上田 智広;中河 啓悟;松浦 秀夫;梶山 梧朗
  78. 1999/10/20, 98) 血漿ノルエピネフリン(NE)高値にも関わらず高血圧を呈しなかった褐色細胞腫の一例, Japanese circulation journal, 木戸 和枝;佐々木 正太;東 幸仁;石田 隆史;植田 篤;吉水 功憲;上田 智広;大上 泰生;栗栖 智;杉野 浩;中河 啓悟;松浦 秀夫;梶山 梧朗;大島 哲也;小園 亮次;石田 万里;松本 敏幸;中野 由紀子;神辺 眞之
  79. 2013/02/28, PADと細胞移植(<特集>動脈硬化とアフェレシス), 日本アフェレシス学会雑誌, 東 幸仁
  80. 1998/02/28, P758 DipperおよびNon-dipper型本態性高血圧患者における自律神経活動の相違, Japanese circulation journal, 中野 由紀子;大島 哲也;小園 亮次;松本 敏幸;神辺 眞之;東 幸仁;佐々木 伸夫;佐々木 正太;植田 篤;吉水 功憲;栗栖 智;松浦 秀夫;梶山 梧朗
  81. 1994/03/01, 本態性高血圧症患者と健常者の食塩抵抗性の機序の差について : 第58回日本循環器学会学術集会, Japanese circulation journal, 大島 哲也;東 幸仁;小園 亮次;平賀 裕之;石田 隆史;石田 万里;渡辺 光章;吉村 光功;小野 法久;中崎 育明;松浦 秀夫;梶山 梧朗
  82. 2003/04/20, 16)冠動脈疾患患者における炎症反応と血管内皮機能の関係, Circulation journal : official journal of the Japanese Circulation Society, 寺田 宏樹;松田 圭司;上田 健太郎;木村 祐之;三浦 史晴;平尾 秀和;大島 哲也;東 幸仁;吉栖 正生
  83. 2005/04/20, 1177 運動強度の違いが酸化ストレスに与える影響(内部障害系理学療法11), 理学療法学, 後藤 力;東 幸仁;西岡 健司;日域 大輔;梅村 隆史;上田 佳子;吉栖 正生
  84. 1996/02/20, 0541 腎機能障害を有する高血圧症患者の内皮依存性腎血管拡張作用 : 正常血圧者および軽症本態性高血圧症患者との比較, Japanese circulation journal, 東 幸仁;石岡 規生;佐々木 伸夫;小野 法久;平賀 裕之;吉村 光功;渡辺 光章;松浦 秀夫;梶山 梧朗;中野 由紀子;大島 哲也
  85. 1997/03/05, 0995 食塩負荷は食塩感受性本態性高血圧患者の夜間降圧を抑制しnon-dipper typeの頻度を増加させる, Japanese circulation journal, 東 幸仁;佐々木 正太;井上 敏明;吉水 功憲;石岡 規生;佐々木 伸夫;吉村 光功;石橋 克彦;松浦 秀夫;梶山 梧朗;松本 敏幸;中野 由紀子;小園 亮次;大島 哲也
  86. 2007/10/20, 150)胸部症状の安定していた冠攣縮性狭心症患者の上顎洞術後に生じた重症冠攣縮(第90回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;西岡 健司;藤井 雄一;出井 尚美;端 孝樹;奥原 宏一郎;渡 雄一郎;久留島 秀治;荘川 知己;東 幸仁;吉栖 正生;大島 哲也;茶山 一彰
  87. 2001/04/20, 298 有酸素運動が血管内皮機能に及ぼす影響, 理学療法学, 後藤 力;東 幸仁;佐々木 正太;中河 啓悟;河村 光俊;奈良 勲
  88. 1995/06/20, 103)特発性アルドステロン症の一例(日本循環器学会第64回中国地方会), Japanese circulation journal, 藤高 一慶;渡辺 光章;東 幸仁;吉村 光功;平賀 裕之;石田 隆史;石田 万里;小野 法久;山形 東吾;唐川 真二;松浦 秀夫;梶山 梧朗;大島 哲也
  89. 1994/03/01, Deoxycorticoster one acetate(DOCA)食塩高血圧ラットにおける血小板Ca^<2+>動態とNa^+濃度 : 第58回日本循環器学会学術集会, Japanese circulation journal, 石田 万里;松浦 秀夫;石田 隆史;小園 亮次;小野 法久;吉村 光功;平賀 裕之;東 幸仁;渡辺 光章;中崎 育明;梶山 梧朗;大島 哲也
  90. 2004/04/20, 96) 上腕動脈の血流依存性拡張反応は冠動脈内皮機能と相関するか?(第83回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;木村 祐之;岡野 勝二;西岡 健司;竹中 創;三浦 史晴;中野 由紀子;茶山 一彰;東 幸仁;吉栖 正生
  91. 2006/04/20, 50)ステント内の器質化血栓をIntegrated Backscatter Intravascular Ultrasoundにて評価した急性冠症候群の1例(第87回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;曽我 潤子;三保 成正;上田 佳子;田渕 久美子;小田 登;尾木 浩;三好 美和;中野 由紀子;茶山 一彰;西岡 健司;東 幸仁;吉栖 正雄;大島 哲也
  92. 2002/04/20, 運動強度の違いが血管内皮機能に及ぼす影響(運動・神経生理), 理学療法学, 後藤 力;東 幸仁;中河 啓吾;木村 祐之;野間 玄督;原 佳子;佐々木 正太;茶山 一彰;河村 光俊;奈良 勲
  93. 2000/04/20, 182) レプチンはヒト末梢血管を拡張する, Japanese circulation journal, 中河 啓悟;東 幸仁;佐々木 正太;大島 哲也;松浦 秀夫;梶山 梧朗
  94. 1999/03/01, 0088 ヒト心筋細胞のアンジオテンシン2タイプ2受容体(AT2)蛋白の発現は心機能と相関する。 : 免疫学的検討, Japanese circulation journal, 松本 敏幸;小園 亮次;中野 由紀子;石田 万里;大島 哲也;中河 啓悟;上田 智広;大上 泰生;杉野 浩;栗栖 智;植田 篤;佐々木 正太;吉水 功憲;東 幸仁;石田 隆史;松浦 秀夫;梶山 梧朗;末田 泰二郎;松浦 雄一郎
  95. 2006/10/20, 242)Framingham risk scoreと冠動脈内皮機能の関係(第88回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 寺川 宏樹;上田 健太郎;曽我 潤子;西岡 健司;日域 大輔;三保 成正;梅村 隆史;東 幸仁;吉栖 正雄;大島 哲也;茶山 一彰
  96. 2007/10/20, 123)心室中隔欠損症手術後シャント残存症例に発症した感染性心内膜炎(第90回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 藤井 雄一;寺川 宏樹;西岡 健司;出井 尚美;端 孝樹;奥原 宏一郎;渡 雄一郎;東 幸仁;吉栖 正生;小園 亮次;大島 哲也;茶山 一彰
  97. 2006/10/20, 246)思いがけず冠攣縮誘発試験がその診断に有用であった2症例(第88回日本循環器学会中国・四国合同地方会), Circulation journal : official journal of the Japanese Circulation Society, 曽我 潤子;寺川 宏樹;上田 健太郎;西岡 健司;日域 大輔;三保 成正;中田 篤範;中野 由紀子;東 幸仁;吉栖 正雄;大島 哲也;茶山 一彰
  98. 2008/04/20, 76) 臨床的にその合併を考えなかったものの心筋生検にて確定診断を得た心アミロイドーシスの1例(第91回日本循環器学会中国地方会), Circulation journal : official journal of the Japanese Circulation Society, 渡邊 紀晶;寺川 宏樹;西岡 健司;光波 直也;藤村 憲崇;槙田 祐子;新宮 哲司;東 幸仁;吉栖 正雄;茶山 一彰

Invited Lecture, Oral Presentation, Poster Presentation

  1. Association between Upstroke Time at the Ankle and Coronary Artery Disease among Subjects with Normal Ankle-brachial Index, Tatsuya Maruhashi, Masato Kajikawa, Shinji Kishimoto, Takayuki Yamaji, Takahiro Harada, Yu Hashimoto, Farina Mohamad Yusoff, Yukiko Nakano, Yukihito Higashi, 2022/03/13, Without Invitation, English, experimental
  2. Relationship between a Body Shape Index and Endothelial Function: FMD-Japan Registry, Masato Kajikawa, Tatsuya Maruhashi, Shinji Kishimoto, Takayuki Yamaji, Takahiro Harada, Yu Hashimoto, Yiming Han, Farina Mohamad Yusoff, Ayumu Nakashima, Yukihito Higashi., 2022/03/11, Without Invitation, English, experimental
  3. Brachial-ankle pulse wave velocity is useful for cardiovascular risk assessment in well-treated hypertensive patients with coronary heart disease, Tatsuya Maruhashi, Masato Kajikawa, Shinji Kishimoto, Takahiro Harada, Yu Hashimoto, Farina Mohamad Yusoff, Yukiko Nakano, Ayumu Nakashima, Bonpei Takase, Hirofumi Tomiyama, Akira Yamashina, Yukihito Higashi, The 29th Scientific Meeting of the International Society of Hypertension, 2022/10/14, Without Invitation, English, experimental
  4. Blood pressure control was improved by a change in the timing of antihypertensive medication in a patient with nocturnal hypertension: a case report, Tatsuya Maruhashi, Yukihito Higashi, The 29th Scientific Meeting of the International Society of Hypertension., 2022/10/13, Without Invitation, English, The 29th Scientific Meeting of the International Society of Hypertension., kyoto, experimental
  5. Impact of underweight, overweight, and obesity on endothelial function: FMD-Japan registry., Masato Kajikawa, Tatsuya Maruhashi, Shinji Kishimoto, Takahiro Harada, Yu Hashimoto, Aya Mizobuchi, Yiming Han, Farina Mohamad Yusoff, Ayumu Nakashima, Yukihito Higashi., the 29th Scientific Meeting of the International Society of Hypertension (ISH2022), 2022/10/16, Without Invitation, English, the 29th Scientific Meeting of the International Society of Hypertension (ISH2022), kyoto, experimental
  6. Convolutional Neural Network-Based Assessment Method for Atherosclerosis Using Earlobe Crease Images., Harutoyo Hirano, Haruki Goto, Satoshi Ota, Masato Futagawa, Yu Hashimoto, Haruki Hashimoto, Shinji Kishimoto, Nozomu Oda, Masato Kajikawa, Tatsuya Maruhashi, Yukihito Higashi., 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2022/07/11, Without Invitation, English, 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), Glasgow, UK, experimental
  7. Sparing and enhancing effects of radiation dose protraction for aortic vascular damage in wild-type mice., Nobuyuki Hamada, Ki-ichiro Kawano, Takaharu Nomura, Kyoji Furukawa, Farina Mohamad Yusoff, Tatsuya Maruhashi, Makoto Maeda, Ayumu Nakashima, Yukihito Higashi., The 68th Annual Meeting of the Radiation Research Society, 2022/10/16, With Invitation, English, The 68th Annual Meeting of the Radiation Research Society, Hawaii, USA, experimental
  8. Update of Vascular Function, Tatsuya Maruhashi, Yukihito Higashi, The 29th Scientific Meeting of the International Society of Hypertension (ISH2022), 2022/10/16, With Invitation, English, ISH2022, kyoto, experimental
  9. Clinical implication of FMD., Yukihito Higashi., The 29th Scientific Meeting of the International Society of Hypertension (ISH2022)., 2022/10/13, With Invitation, English, ISH2022, Kyoto, experimental
  10. Role of triglycerides in residual risk of cardiovascular events., Yukihito Higashi., he 19th International Symposium on Atherosclerosis (ISA2021), 2021/10/25, With Invitation, English
  11. Association of Extremely High Levels of High-density Lipoprotein Cholesterol with Endothelial Dysfunction in Men., Yuji Takaeko, Shogo Matsui, Masato Kajikawa, Tatsuya Maruhashi, Shinji Kishimoto, Haruki hashimoto, Yukihito Higashi., 92th Scientific Sessions, American Heart Association, 2019/11, Without Invitation, English, 92th Scientific Sessions, American Heart Association, Philadelphia
  12. Eplerenone Improves Vascular Function, Arterial Stiffness and Rho-associated Kinase Activity in Patients with Idiopathic Hyperaldosteronism, Shinji Kishimoto, Yukihito Higashi, Takayuki Yamaji, Takahiro Harada cYuji Takaeko, Farina Mohamad Yusoff, Haruki Hashimoto, Shogo Matsui, Masato Kajikawa, Tatsuya Maruhashi, Kensuke Noma, Yasuki Kihara, 92th Scientific Sessions, American Heart Association, 2019/11, Without Invitation, English, 92th Scientific Sessions, American Heart Association, Philadelphia
  13. Association Between Endothelial Function Measured by Enclosed Zone Flow-mediated Vasodilation and Cardiovascular Risk Factors, 92th Scientific Sessions, American Heart Association, 2019/11, Without Invitation, English, 92th Scientific Sessions, American Heart Association, Philadelphia.
  14. Patients with Diastolic Ventricular Hypertrophy and Ventricular Dysfunction may occur Heart Failure with Preserved Ejection Fraction through Endothelial Dysfunction, Shinji Kishimoto, Yukihito Higashi, Takayuki Yamaji, Takahiro Harada, Yuji Takaeko, Farina Mohamad Yusoff, Haruki Hashimoto, Masato Kajikawa, Tatsuya Maruhashi, Takayuki Hidaka, Yasuki Kihara, 2019/10, Without Invitation, English
  15. Short-term effect of empagliflozin on endothelial function in patients with type 2 diabetes and cardiovascular diseases: a placebo-controlled randomised trial (EMBLEM), Atsushi Tanaka, Yukihito Higashi, Koichi Node, ESAD 2019, 2019/09, Without Invitation, English, ESAD 2019, Spain
  16. Nocturia is a Predictor of Cardiovascular Events in the Elderly Population: Two-year Follow-up of Multicenter Observational Study, Shogo Matsui, Yukihito Higashi, Masato Kajikawa, Tatsuya Maruhashi, Shinji Kishimoto, Haruki Hashimoto, Takayuki Hidaka, Farina Mohamad Yusoff, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara, 2019/03, Without Invitation, English
  17. Association of Oral Health Based on Tooth Brushing Behavior with Cardiovascular Outcome: Two-year Follow-up Prospective Observational Study, Shogo Matsui, Yukihito Higashi, Masato Kajikawa, Tatsuya Maruhashi, Shinji Kishimoto, Haruki Hashimoto, Takayuki Hidaka, Farina Mohamad Yusoff, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara., 2019/03, Without Invitation, English
  18. Eplerenone Improves Endothelial Function, Arterial Stiffness and Rho-associated Kinase Activity in Patients with Idiopathic Hyperaldosteronism, Shinji Kishimoto, Yukihito Higashi, Yuji Takaeko, Farina Mohamad Yusoff, Haruki Hashimoto, Shogo Matsui, Masato Kajikawa, Tatsuya Maruhashi, Kensuke Noma, Yasuki Kihara, 2019/03, Without Invitation, English
  19. Endothelial Function Measured by Enclosed Zone Flow-mediated Vasodilation and Cardiovascular Risk Factors, Masato Kajikawa, Haruka Morimoto, Haruki Hashimoto, Shogo Matsui, Tatsuya Maruhashi, Shinji Kishimoto, Takayuki Hidaka, Farina Mohamad Yusoff, Yasuki Kihara, Kensuke Noma, Ayumu Nakashima, Teiji Ukawa, Toshio Tsuji, Yukihito Higashi, 2019/03, Without Invitation, English
  20. Role of Resisting-like Molecule b in Akt/ AMPK/Hsp90/eNOS Pathway, Shinji Kishimoto, Yuji Takaeko, Farina Mohamad Yusoff, Haruki Hashimoto, Shogo Matsui, Masato Kajikawa, Tatsuya Maruhashi, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara, Yukihito Higash, 2019/01, Without Invitation, English, FUKUSHIMA
  21. Assessment of endothelial function, Higashi Yukihito, Artery2018, 2018/10, With Invitation, English, Artery2018, Portugal
  22. BPH/LUTSと血管内皮機能, Higashi Yukihito, 第68回日本泌尿器学会中部総会, 2018/10, With Invitation, Japanese, 第68回日本泌尿器学会中部総会, Nagoya
  23. Endothelial function and inflammation, Higashi Yukihito, WCP2018, 2018/07, With Invitation, Japanese, WCP2018, Kyoto
  24. 血管機能より動脈硬化を考える, Higashi Yukihito, KyushuPRevent 2018, 2018/05/13, With Invitation, Japanese, KyushuPRevent 2018, Fukuoka
  25. Concept and new evidence of vascular biomarker: FMD, Higashi Yukihito, The 15th Pulse of Asia, 2018/05, With Invitation, English, The 15th Pulse of Asia, Kyoto
  26. 血管内皮機能の心血管病における役割, Higashi Yukihito, 第71回日酸化ストレス学会/第18回日本NO学会合同学術集会, 2018/05, With Invitation, Japanese, 第71回日酸化ストレス学会/第18回日本NO学会合同学術集会, Kyoto
  27. 多施設共同研究FMD-Jから見えてきたもの, Higashi Yukihito, 第3回日本血管不全学会, 2018/04, With Invitation, Japanese, 第3回日本血管不全学会, Kyoto
  28. Endothelial function and therapeutic angiogenesis in patients with critical limb ischemia., Higashi Yukihito, 第82回日本循環器学会総会, 2018/03, With Invitation, Japanese, 第82回日本循環器学会総会, Osaka
  29. Endothelial function and therapeutic angiogenesis in patients with critical limb ischemia., Higashi Yukihito, 第81回日本循環器学会総会, 2017/03, With Invitation, English, 第81回日本循環器学会総会, Kanazawa
  30. Measurement of Flow-mediated Vasodilation (FMD), Tatsuya Maruhashi, Yasuki Kihara, Yukihito Higashi, 2016/12/09, With Invitation, Japanese, Nagasaki
  31. Light to Moderate Alcohol Consumption Does Not Alter Endothelial Function., Nozomu Oda, Yukihito Higashi, Masato Kajikawa, Tatsuya Maruhashi, Shinji Kishimoto, Shogo Matsui, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Hirofumi Tomiyama, Bonpei Takase, Akira Yamashina, Yasuki Kihara., 89th Scientific Session, American Heart Association, 2016/11/15, Without Invitation, English, 89th Scientific Session, American Heart Association, New Orlrans
  32. A Significant Correlation Between Nitroglycerine-induced Vasodilation in Coronary and Brachial Arteries, Tatsuya Maruhashi, Yukihito Higashi, Masato Kajikawa, Ayumu Nakashima, Yumiko Iwamoto, Akimichi Iwamoto, Nozomu Oda, Shinji Kishimoto, Shogo Matsui, Tadanao Higaki, Takashi Shimonaga, Noriaki Watanabe, Hiroki Ikenaga, Takayuki Hidaka, Yoshiki Aibara, Kensuke Noma, Yasuki Kihara, 89th Scientific Sessions, American Heart Association, 2016/11/13, Without Invitation, English, 89th Scientific Sessions, American Heart Association, New Orleans
  33. Vascular Function and Rho-associated Kinase Activity in Patients with Idiopathic hyperaldosteronism, Shinji Kishimoto, Takeshi Matsumoto, Shogo matsui, Nozomu Oda, Masato Kajikawa, Yumiko Iwamoto, Tatsuya Maruhashi, Ayumu Nakashima, Takayuki Hidaka, Kensuke Noma, Yasuki Kihara, Yukihito Higashi., Pulse of Asia 2016, 2016/09/25, Without Invitation, English, Pulse of Asia 2016, Seoul
  34. Impact of Triglycerides as Residual Risk for Cardiovascular Events on Endothelial Function: FMD-Japan Registry, Masato Kajikawa, Tatsuya Maruhashi, Nozomu Oda, Shinji Kishimoto, Shogo Matsui, Takayuki Hidaka, Yasuki Kihara, Kensuke Noma, Ayumu Nakashima, Hirofumi Tomiyama, Bonpei Takase, Akira Yamashina, Yukihito Higashi, The Pulse of Asia 2016, 2016/09/25, Without Invitation, English, The Pulse of Asia 2016, Seoul
  35. Endothelial Function Is Impaired in Subjects with Decreased Frequency and Duration of Tooth Brushing., Shogo Matsui, Yukihito Higashi, Masato Kajikawa, Tatsuya Maruhashi, Akimichi Iwamoto, Nozomu Oda, Shinji Kishimoto, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara., Pulse of Asia 2016, 2016/09/25, Without Invitation, English, Pulse of Asia 2016, Seoul
  36. Endothelial function, hypertension, and aging., Yukihito Higashi, Pulse of Asia, 2016/09/24, With Invitation, English, Pulse of Asia, Soul
  37. Vascular Smooth Muscle function in Coronary and Brachial Arteries in Patients with Suspected Coronary Artery Disease, Tatsuya Maruhashi, Masato Kajikawa, Ayumu Nakashima, Yumiko Iwamoto, Akimichi Iwamoto, Nozomu Oda, Shinji Kishimoto, Shogo Matsui, Kensuke Noma, Yasuki Kihara, Yukihito Higashi, The Pulse of Asia 2016, 2016/09/24, Without Invitation, English, The Pulse of Asia 2016, Seoul
  38. One-Year Prevalence of Cerebrovacular and Heart Diseases among 996,637 Employees Based on Medical Claim and Health Checks in Japan., Arata Matsushima, Hiroyuki Aizu, Masayo Yamato, Masayuki Ohisa, Basilua Andre Muezembo, mami Yamashita, Aya Sugiyama, Masayasu Yoneda, Yukihito Higashi, Junko Tanaka, The 48th Asia-Pacofoc Accademic Consortium for Public Health Conference, 2016/09/16, Without Invitation, English, The 48th Asia-Pacofoc Accademic Consortium for Public Health Conference, Tokyo
  39. Endothelial function and hypertension, Yukihito Higashi, The 6th Chinese Society of Hypertension, 2016/07/24, With Invitation, English, The 6th Chinese Society of Hypertension, Changchun
  40. Endothelial function and hypertension, Yukihito Higashi, The 6th International Hypertension Meeting, 2016/07, With Invitation, English
  41. Endothelial function and oxidative stress., Yukihito Higashi, The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide, 2016/05/22, With Invitation, English, The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide, Sendai
  42. Endothelial function and oxidative stress, Higashi Yukihito, The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide, 2016/05, With Invitation, Japanese, The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide, sendai
  43. Endothelial Function is impaired in Subjects with Increased Serum Triglyceride Levels, Masato Kajikawa, Yukihito Higashi, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi Iwamoto, Nozomu Oda, Shinji Kishimoto, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Hirofumi Tomiyama, Bonpei Takase, Akira Yamashina, Yasuki Kihara, 2016/03/19, Without Invitation, English, Sendai
  44. Reliability of Endothelial Function Assessment Using a Semi-automated Device across Multiple Institutions and Establishment of Normal/Reference Values., Hirofumi Tomiyama, Yukihito Higashi, Akira Yamashina., 2016/03/18, With Invitation, English, Tokyo
  45. Vascular Function and Vascular Structure are Impaired in Patients with Heart Failure with Preserved Ejection Fraction, Shinji Kishimoto, Yukihito Higashi, Nozomu Oda, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yumiko Iwamoto, Tatsuya Maruhashi, Ayumu Nakashima, Takayuki Hidaka, Kensuke Noma, Yasuki Kihara., 2016/03/18, Without Invitation, Japanese, Sendai
  46. Endothelial Function Is Impaired in Subjects with Decreased Frequency of Tooth Brushing., Masato Kajikawa, Yukihito Higashi, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi iwamoto, Takeshi Matsumoto, Nozomu Oda, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara., 87th Scientific Sessions, American Heart Association, 2014/11, Without Invitation, English, Chicago, IL.
  47. Prognostic Value of Combination of Flow-mediated Vasodilation and Nitroglycerine-induced Vasodilation., Masato Kajikawa, Yukihito Higashi, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi iwamoto, Takeshi Matsumoto, Nozomu Oda, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara., 87th Scientific Sessions, American Heart Association, 2014/11, Without Invitation, English, Chicago, IL.
  48. Endothelial Function Is Impaired in Peripheral Arterial Disease with Borderline Ankle-Brachial Index., Masato Kajikawa, Yukihito Higashi, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi iwamoto, Takeshi Matsumoto, Nozomu Oda, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara., 87th Scientific Sessions, American Heart Association, 2014/11, Without Invitation, English
  49. Nitroglycerine-induced Vasodilation was Significantly Impaired in Peripheral Artery Disease-patients with Critical Limb Ischemia Compared with Those without., Tatsuya Maruhashi, Yukihito Higashi, Nozomu Oda, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yumiko Iwamoto, Ayumu Nakashima, Takayuki Hidaka, Kensuke Noma, Yasuki Kihara., 87th Scientific Sessions, American Heart Association, 2014/11, Without Invitation, English, Chicago, IL.
  50. A Comparison of Nitroglycerine-induced Vasodilation with Flow-mediated Vasodilation as a Cardiovascular Risk Marker., Tatsuya Maruhashi, Nozomu Oda, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yumiko Iwamoto, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara, Yukihito Higashi., European Society of Cardiology Congress 2014, 2014/09, Without Invitation, English, Barcelona
  51. Regulation of eNOS mRNA destabilization via ROCK2-mediated eEF1A1 phosphorylation, Kensuke Noma, James K Liao, Yasuki Kihara, Yukihito Higashi, 19th World Congress on Heart Disease. International Academy of Cardiology Annual Scientific Sessions 201, 2014/07, With Invitation, English, Boston, MA, USA
  52. Clinical Impact of ROCK in Sustained Vasoconstriction in Patients with Essential Hypertension., Kensuke Noma, Chikara Goto, Yasuki Kihara, Yukihito Higashi., 2014/07, With Invitation, English
  53. Gidelines for Non-invasive Vascular Function Test (JCS 2013): Endothelial Function., Yukihito Higashi, The 11th Pulse of Asia, 2014/06, With Invitation, Japanese, Athena, Greece
  54. Relationships between Nitroglycerine-induced Vasodilation in the Brachial Artery and Cardiovascular Risk Factors., Tatsuya Maruhashi, Nozomu Oda, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yumiko Iwamoto, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara, Yukihito Higashi., The 11th Pulse of Asia 2014, 2014/06, Without Invitation, English, Athena, Greece
  55. Impact of Aldosterone Producing Adenoma on Endothelial Function in Patients With Primary Aldosteronism., Takeshi Matsumoto, Nozomu Oda, Akimichi Iwamoto, Yumiko Iwamoto, Masato Kajikawa, Tatsuya Maruhashi, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara, Yukihito Higashi., The 11th Pulse of Asia, 2014/06, Without Invitation, English, Athena, Greece
  56. Combination of Flow-mediated Vasodilation and Nitroglycerine-induced Vasodilation for Prediction of Cardiovascular Events., Masato Kajikawa, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi iwamoto, Takeshi Matsumoto, Takayuki Hidaka, Ayumu Nakashima, Kensuke Noma, Yasuki Kihara, Yukihito Higashi., The 11th Pluse of Asia, 2014/06, Without Invitation, English, Athena, Greece
  57. ROCK Activity and Endothelial Function: Potential Candidates for Vascular and Anti-aging Biomarkers, 2014/06, With Invitation, English
  58. Destabilization of eNOS mRNA via ROCK2-mediated eEF1A1 phosphorylation., 2014/05, Without Invitation, English
  59. Uric Acid and Endothelial Function: Role of Oxidative Stress., Yukihito Higashi, The 17th International Vascular Biology Meeting, 2014/04, With Invitation, English, Kyoto
  60. Role of ROCK in Sustained Arterial Vasoconstriction in Patients with Essential Hypertension., Kensuke Noma, Chikara Goto, Yasuki Kihara, James K Liao, Yukihito Higashi., The 18th International Vascular Biology Meeting (IVBM 2014), 2014/04, Without Invitation, English
  61. Therapeutic Angiogenesis and Endothelial Function in Patients with Peripheral Artery Disease., 2014/03, With Invitation, English
  62. Six months follow-up of cardiovascular events in patients with ASO treated with antiplatelet agents: Interim report from SEASON., Yukihito Higashi, Tetsuro Miyata, Hiroshi Shigematsu, Hideki Origasa, Masatoshi Fujita, Hiroshi Matsuo, Hiroaki Naritomi, Hiroaki Matsuda., 2014/03, With Invitation, English
  63. Nitroglycerine-induced Vasodilation in the Brachial Artery and Cardiovascular Risk Factors., Tatsuya Maruhashi, Yukihito Higashi, Nozomu Oda, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yumiko Iwamoto, Ayumu Nakashima, Takayuki Hidaka, Kensuke Noma, Yasuki Kihara., 2014/03, Without Invitation, English
  64. ROCK as a Modulator of Sustained Vasoconstriction of ResistanceArtery in Patients with Essential Hypertension., Kensuke Noma, Chikara Goto, Yasuki Kihara, James K Liao, Yukihito Higashi., 2014/03, Without Invitation, English
  65. Difference Between Nitroglycerine-induced Vasodilation and Flow-mediated Vasodilation in Association with the Severity of Atherosclerosis., Tatsuya Maruhashi, Yukihito Higashi, Nozomu Oda, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yumiko Iwamoto, Ayumu Nakashima, Takayuki Hidaka, Kensuke Noma, Yasuki Kihara., 2014/03, Without Invitation, English
  66. Poor Oral Health Behavior is Associated with Endothelial Dysfunction., Masato Kajikawa, Yukihito Higashi, Kensuke Noma, Takayuki Hidaka, Ayumu Nakashima, Shinsuke Mikami, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi Iwamoto, Yasuki Kihara., 2014/03, Without Invitation, Japanese
  67. Rho-Associated Kinase Activity and Risk of Cardiovascular Events., Masato Kajikawa, Yukihito Higashi, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi iwamoto, Takeshi Matsumoto, Takayuki Hidaka, Ayumu Nakashima, James K. Liao, Kensuke Noma, Yasuki Kihara., 2014/03, Without Invitation, English
  68. Regulation of eNOS mRNA stability vie ROCK2-mediated phosphorylation of eEF1A., 2014/02, Without Invitation, English
  69. Low Intensity Pulsed Ultrasound Induced Angiogenesis through Activation of Integrin Signaling in Endothelial Cells., 2014/02, Without Invitation, English

External Funds

Acceptance Results of Competitive Funds

  1. 2022
  2. Promoting Clinical Trials for Development of New Drugs and Medical Devices, 2021/04/01, 2022/03/31
  3. Research Project for Practical Applications of Regenerative Medicine, 2021/04/01, 2022/03/31
  4. Practical Research Project for Life-Style related Diseases including Cardiovascular Diseases and Diabetes Mellitus, 2015/04/01, 2016/03/31
  5. KAKENHI, 2013, 2015
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  6. KAKENHI, 2012, 2014
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  7. KAKENHI, Role of ROCK activity in cardiovascular diseases: a translational research, 2011, 2013
    Permalink
  8. KAKENHI, Development of Diagnostic System of Vascular Function for Assessment of Atherosclerosis, 2009, 2011
    Permalink
  9. KAKENHI, Development of oral health-related indices for identifying individuals with increased risk of ischemic cardiovascular diseases, 2009, 2011
    Permalink
  10. KAKENHI, Therapeutic Angiogenesis with Autologous Mesenchymal Stem Cell in Patients with Peripheral Artery Diseases: Mesenchymal Stem Cell Storing System, 2006, 2007
    Permalink
  11. KAKENHI, 2005, 2007
    Permalink
  12. KAKENHI, 2004, 2005
    Permalink
  13. KAKENHI, Systematization of Non-invasive Evaluation of Atherosclerosis in Clinical Laboratory Medicine, 2003, 2004
    Permalink
  14. KAKENHI, Autologous Bone-marrow Mononuclear Cell Implantation in Patients with Peripheral Artery Diseases : Mesenchymal Stem Cell Acute Culture Method and Assessment of Endothelial Function in Angiogenesis, 2003, 2004
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  15. Health and Labour Sciences Research Grants, 2014/07/23, 2015/03/31
  16. KAKENHI, 2013, 2015
    Permalink
  17. KAKENHI, 2015, 2018
  18. KAKENHI, 2015
  19. Practical Research Project for Life-Style related Diseases including Cardiovascular Diseases and Diabetes Mellitus , 2016/04/01, 2017/03/31
  20. 2016
  21. KAKENHI, 2016, 2018
  22. KAKENHI, 2016
  23. KAKENHI, 2016, 2019
  24. KAKENHI, 2016, 2018
  25. Promoting Clinical Trials for Development of New Drugs and Medical Devices , 2017/05/01, 2018/03/31
  26. Development of Medical Devices through Collaboration between Medicine and Industry , 2017/04/14, 2018/03/31
  27. Promoting Clinical Trials for Development of New Drugs and Medical Devices , 2018/04/01, 2019/03/31
  28. Research Project for Practical Applications of Regenerative Medicine , 2019/04/01, 2020/03/31
  29. Promoting Clinical Trials for Development of New Drugs and Medical Devices , 2019/04/01, 2020/03/31
  30. Promoting Clinical Trials for Development of New Drugs and Medical Devices, 2020/04/01, 2021/03/31
  31. Research Project for Practical Applications of Regenerative Medicine, 2020/04/01, 2021/03/31

Social Activities

Organizing Academic Conferences, etc.

  1. 2021/05, 2021/05
  2. The 2nd Annual Scientific Meeting of Japan Society for Vascular Failure, 2017/04, 2017/04
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  3. 脳心血管抗加齢研究会2018, 学会長, 2018/12, 2018/12
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Other Social Contributions

  1. 広島南警察署講演会, 健康な体は正常な血管から, 広島南警察署, IZUMI, 2019/05/15, 広島南警察署, Lecturer, Lecture, Governmental agency
  2. 市民公開講座 おしっこのトラブルと生活習慣病, おしっこと血管の意外なつながり, 朝日新聞社, 朝日新聞社, 2018/03/20, 2018/03/20, Lecturer, Newspaper or magazine, General
  3. 林修の今でしょ！講座, 林修の今でしょ！講座, テレビ朝日, テレビ朝日, 2018/07/03, Lecturer, TV or radio program, General