広島大学

Basic Information

Major Professional Backgrounds

• 2020/04, Hiroshima University Research Institute for Radiation Biology and Medicine, Department of Disease Model, Assistant Professor
• 2017/04, 2020/03, RIKEN BioResource Research Center, Bioresource Engineering Division, Postdoctoral Researcher

Educational Backgrounds

• The University of Tokyo, Graduate School of Agricultural and Life Sciences, Veterinary Medical Science, 2013/04, 2017/03
• The University of Tokyo, Faculty of Agriculture, Veterinary Medical Science, 2007/04, 2013/03

Academic Degrees

• The University of Tokyo

Educational Activity

• [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine
• [Master's Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences : Program of Biomedical Science
• [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences : Program of Biomedical Science
• [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Radiation Biology and Medicine

Affiliated Academic Societies

• THE JAPANESE SOCIETY OF VETERINARY SCIENCE
• SOCIETY FOR REPRODUCTION AND DEVELOPMENT
• JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE

Educational Activity

Course in Charge

1. 2024, Liberal Arts Education Program1, 1Term, Foundation biology for life science
2. 2024, Undergraduate Education, Intensive, Practice for medical research
3. 2024, Undergraduate Education, 1Term, Dysphagia Rehabilitation
4. 2024, Undergraduate Education, 1Term, Dysphagia Rehabilitation
5. 2024, Undergraduate Education, 1Term, Dysphagia Rehabilitation
6. 2024, Graduate Education (Master's Program) , First Semester, Seminar
7. 2024, Graduate Education (Master's Program) , Second Semester, Seminar
8. 2024, Graduate Education (Master's Program) , First Semester, Research
9. 2024, Graduate Education (Master's Program) , Second Semester, Research
10. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar
11. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar
12. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research
13. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research
14. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Disease Model
15. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Disease Model
16. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Disease Model
17. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Disease Model
18. 2024, Graduate Education (Doctoral Program) , Second Semester, Introduction to Radiation Biology
19. 2024, Graduate Education (Master's Program) , OutOfTerm(1st), Basic Training of Genome Editing

Research Activities

Academic Papers

1. Paternal knockout of Slc38a4/SNAT4 causes placental hypoplasia associated with intrauterine growth restriction in mice., Proceedings of the National Academy of Sciences of the United States of America, 116(42), 21047-21053, 201910
2. ★, Molecular and genetic characterization of partial masculinization in embryonic ovaries grafted into male nude mice., PloS one, 14(3), e0212367, 2019
3. ★, Application of auxin-inducible degron technology to mouse oocyte activation with PLCz., The Journal of reproduction and development, 64(4), 319-326, 201808
4. CRISPR/Cas9-mediated knock-in of the murine Y chromosomal Sry gene., The Journal of reproduction and development, 64(3), 283-287, 2018
5. ★, Defects in the first wave of folliculogenesis in mouse XO ovaries., The Journal of reproduction and development, 63(3), 333-338, 201706
6. In vivo dynamics of GFRa1-positive spermatogonia stimulated by GDNF signals using a bead transplantation assay., Biochemical and biophysical research communications, 476(4), 546-552, 2016
7. Production of Sry knockout mouse using TALEN via oocyte injection., Scientific reports, 3, 3136, 2013
8. Heterogeneity in sexual bipotentiality and plasticity of granulosa cells in developing mouse ovaries., Journal of cell science, 126(Pt 13), 2834-2844, 2013
9. Early gonadogenesis in mammals: significance of long and narrow gonadal structure., Developmental dynamics : an official publication of the American Association of Anatomists, 242(4), 330-8, 2013
10. ★, Generation of chimeric mice with spermatozoa fully derived from embryonic stem cells using a triple-target CRISPR method for Nanos3, Biology of reproduction, 2021
11. ★, Role of CD4 + T Cells in Allergic Airway Diseases: Learning from Murine Models, International Journal of Molecular Science, 21(20), 7480, 2020
12. Suppressive effect of dexamethasone on murine Th9 cell-mediated nasal eosinophlic inflammation, ASIA PACIFIC ALLERGY, 11(3), 202107
    Link to Paper Search Results by DOI
13. L-type amino acid transporter 1 inhibitor suppresses murine Th2 cell-mediated bronchial hyperresponsiveness independently of eosinophil accumulation, ASIA PACIFIC ALLERGY, 11(3), 20210719
    Link to Paper Search Results by DOI
14. Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas, Nature Communications, 2020
15. Early Crypt Formation Defects in the Uterine Epithelia of Sox17 Heterozygous Mice, Sexual Development, 2021

Publications such as books

1. 2018, Reproductive and Developmental Strategies: the Continuity of Life., Sex Determination and Differentiation in Mammals, Springer, Joint work

Awards

1. 2019, Journal of Reproduction and Development Outstanding Paper Award in 2018, "Application of auxin-inducible degron technology to mouse oocyte activation with PLCz", J Reprod Dev 64(4): 319–326, 2018
2. 2018, Journal of Reproduction and Development Outstanding Paper Award in 2017, "Defects in the first wave of folliculogenesis in mouse XO ovaries", J. Reprod. Dev. 63(3): 333–338, 2017
3. 2013, The Dean Award for Academic Excellence