NAOTO HIROSE

Last Updated :2024/04/23

Affiliations, Positions
Hiroshima University Hospital(Dental), Associate Professor or Lecturer
Web Site
https://orthod.hiroshima-u.ac.jp/
E-mail
hirosehiroshima-u.ac.jp
Other Contact Details
1-2-3，Kasumi，Minami-ku，Hiroshima, Japan
TEL : (+81) FAX : (+81)
Self-introduction
My specialty is orthodontics. The research field is about teeth development and enamel proteins, especially Ameloblastin, and temporomandibular disorders(TMD) including osteoarthritis. Another area of my study is about bone diseases, tissue regeneration,inflammatory diseases.

Basic Information

Major Professional Backgrounds

  • 2022/10/01, Department of Orthodontics, Division of Oral Health and Development, Hiroshima University Hospital, Associate professor
  • 2021/04/01, Hiroshima University, Hospital, Lecturer
  • 2006/04/17, 2006/04/30, Hiroshima University, Hospital, Clinical Resident
  • 2006/05/01, 2006/09/30, Iris dental clinic, Clinical Resident
  • 2006/10/01, 2007/03/31, Hiroshima University, Hospital, Clinical Resident
  • 2007/04/01, 2008/03/31, Hiroshima University, Hospital, Clinical Fellow
  • 2011/04/01, 2013/10/31, Hiroshima University, Hospital, Clinical Fellow
  • 2013/11/01, 2019/03/31, Hiroshima University, Institute of Biomedical & Health Sciences, Assistant Professor
  • 2019/04/01, 2021/03/31, Hiroshima University, Graduate School of Biomedical & Health Sciences, Assistant Professor

Educational Backgrounds

  • Hiroshima University, Japan, 2007/04, 2011/03
  • Hiroshima University, Japan, 2000/04, 2006/03

Academic Degrees

  • Doctor of Philosophy in Dental Science, Hiroshima University

Educational Activity

  • [Bachelor Degree Program] School of Dentistry : Program of Dentistry : Dentistry
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Dental Sciences

In Charge of Primary Major Programs

  • Dentistry

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Orthodontics / Pediatric dentistry
  • Medicine,dentistry, and pharmacy;Dentistry;Morphological basic dentistry
  • Medicine,dentistry, and pharmacy;Dentistry;Functional basic dentistry
  • Medicine,dentistry, and pharmacy;Dentistry;Dental engineering / Regenerative dentistry

Research Keywords

  • enamel proteins
  • temporomandibular joint disorder
  • regeneration medicine
  • Root resorption
  • Cell adhesion
  • Cell proliferation
  • Chondrocytes
  • Cell　differentiation

Affiliated Academic Societies

  • Japanese Orthodontic society
  • Chu-Shikoku orthodontic society
  • The Japanese society for Tempormandibular Joint
  • Japanese Cleft palate Association
  • The Japanese Society for Jaw Deformities
  • World federation of orthodontics
  • JADR, 2018/12
  • IADR, 2018/12

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, 4Term, Overview of Dentistry
  2. 2024, Undergraduate Education, 3Term, Stomatognathic Function
  3. 2024, Undergraduate Education, 1Term, Orthodontics I
  4. 2024, Undergraduate Education, 2Term, Orthodontics II
  5. 2024, Undergraduate Education, First Semester, Dental Research Practices I
  6. 2024, Undergraduate Education, 3Term, Basic Practice of Orthodontics I
  7. 2024, Undergraduate Education, 4Term, Basic Practice of Orthodontics II
  8. 2024, Undergraduate Education, Second Semester, Dental Research Practices II
  9. 2024, Undergraduate Education, 2Term, Advanced Course in Growth and Development of Occlusion
  10. 2024, Undergraduate Education, 2Term, General Seminar on Clinical Dentistry
  11. 2024, Undergraduate Education, First Semester, Dental Research Practices III
  12. 2024, Undergraduate Education, Academic Year, Clinical Practice (Preventive Dentistry)
  13. 2024, Undergraduate Education, Academic Year, Clinical Practice (Orthodontics)
  14. 2024, Undergraduate Education, Second Semester, Clinical Practice on Oral Health
  15. 2024, Undergraduate Education, Intensive, Clinical practice on oral health
  16. 2024, Undergraduate Education, Intensive, Clinical Practice on Oral Health Management
  17. 2024, Undergraduate Education, 3Term, Practice of Orthodontics I
  18. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Orthodontics and Craniofacial Developmental Biology
  19. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Orthodontics and Craniofacial Developmental Biology
  20. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Orthodontics and Craniofacial Developmental Biology
  21. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Orthodontics and Craniofacial Developmental Biology
  22. 2024, Graduate Education (Doctoral Program) , First Semester, Training Course for Orthodontic Specialist
  23. 2024, Graduate Education (Doctoral Program) , Second Semester, Training Course for Orthodontic Specialist

Research Activities

Academic Papers

  1. Longitudinal effects of estrogen on mandibular growth and changes in cartilage during the growth period in rats, DEVELOPMENTAL BIOLOGY, 492, 126-132, 20221201
    Link to Paper Search Results by DOI
  2. Orthodontic Treatment for a Patient with Root Resorption of All Four Maxillary Incisors due to Bilaterally Impacted Canines, CASE REPORTS IN DENTISTRY, 2022, 20220919
    Link to Paper Search Results by DOI
  3. High-frequency near-infrared diode laser irradiation suppresses IL-1 beta-induced inflammatory cytokine expression and NF-kappa B signaling pathways in human primary chondrocytes, LASERS IN MEDICAL SCIENCE, 37(2), 1193-1201, 202203
    Link to Paper Search Results by DOI
  4. Characteristics of the Maxillofacial Morphology in Patients with Idiopathic Mandibular Condylar Resorption, JOURNAL OF CLINICAL MEDICINE, 11(4), 20220211
    Link to Paper Search Results by DOI
  5. Effects of Low-Intensity Pulsed Ultrasound on the Expression of Cyclooxygenase-2 in Mandibular Condylar Chondrocytes, JOURNAL OF ORAL & FACIAL PAIN AND HEADACHE, 28(3), 261-268, 2014
    Link to Paper Search Results by DOI
  6. Effects of Enzymatic Degradation after Loading in Temporomandibular Joint, JOURNAL OF DENTAL RESEARCH, 94(2), 337-343, 201502
    Link to Paper Search Results by DOI
  7. Celecoxib exerts protective effects on extracellular matrix metabolism of mandibular condylar chondrocytes under excessive mechanical stress., 201406
  8. ★, Ameloblastin in Hertwig’s Epithelial Root Sheath Regulates Tooth Root Formation and Development, 8, 1-8, 2013
  9. P2X7 receptor in the trigeminal sensory nuclear complex contributes to tactile allodynia/　hyperalgesia following trigeminal nerve injury:, European Journal of Pain, 17, 185-199, 2013
  10. Effects of hyaluronan oligosaccharides on apoptosis of human gingival fibroblasts, Open Journal of Stomatology, 3, 19-24, 2013
  11. Longitudinal changes in the height and location of bone bridge from autogenous iliac bone graft in patients with cleft lip and palate:, Open Journal of Stomatology, 3, 58-62, 2013
    Link to Paper Search Results by DOI
  12. P2X7 Receptor and Cytokines Contribute to Extra-territorial Facial Pain:, Journal of Dental Research, 92, 260-265, 2013
  13. Effects of bFGF on the modulation of apoptosis in gingival fibroblasts with different host ages:, .: Interantional Journal of Dentistry, 2013
  14. Synthesis of hyaluronan and superficial zone protein in synovial membrane cells modulated by fluid flow:, European Journal of Oral Sciences, 121, 566-572, 2013
  15. ★, The Second Report: A case of Temporomandibular Joint Osteoarthritis with Mandibular Recession and Open Bite: Onset after the Orthodontic Treatment in Adolescence, 第48巻(第２号), 56-62, 2016
  16. ★, A Case of Temporomandibular Joint Osteoarthritis with Mandibular Recession and Open Bite, 第４４巻(第２号), １３８-１４３, 2012
  17. Effects of C-Terminal Amelogenin Peptide on Proliferation of Human Cementoblast Lineage Cells, JOURNAL OF PERIODONTOLOGY, 87(7), 820-827, 201607
    Link to Paper Search Results by DOI
  18. Effects of C-terminal amelogenin peptides on the metabolism of osteoblasts, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 482(4), 1154-1159, 20170122
    Link to Paper Search Results by DOI
  19. The C-terminus of amelogenin enhances osteogenic differentiation of human cementoblast lineage cells, JOURNAL OF PERIODONTAL RESEARCH, 52(2), 218-224, 201704
    Link to Paper Search Results by DOI
  20. Hyaluronan enhances proteoglycan4 expression in synovial cells, 5(2), 2017
  21. The C-terminus of the amelogenin peptide influences the proliferation of human bone marrow mesenchymal stem cells, JOURNAL OF PERIODONTOLOGY, 89(4), 496-505, 201804
    Link to Paper Search Results by DOI
  22. Semaphorin 3A Inhibits Inflammation in Chondrocytes under Excessive Mechanical Stress, MEDIATORS OF INFLAMMATION, 2018
    Link to Paper Search Results by DOI
  23. Effects of high-frequency near-infrared diode laser irradiation on the proliferation and migration of mouse calvarial osteoblasts, LASERS IN MEDICAL SCIENCE, 33(5), 959-966, 201807
    Link to Paper Search Results by DOI
  24. Effect of high-frequency near-infrared diode laser irradiation on periodontal tissues during experimental tooth movement in rats, LASERS IN SURGERY AND MEDICINE, 50(7), 772-780, 201809
    Link to Paper Search Results by DOI
  25. Cyclic Tensile Strain Upregulates Pro-Inflammatory Cytokine Expression Via FAK-MAPK Signaling in Chondrocytes, INFLAMMATION, 41(5), 1621-1630, 201810
    Link to Paper Search Results by DOI
  26. ★, a comprehensive orthodontic-prosthetic treatment of crowding with loss of an upper central incisor and alveolar bone defect by an accident, 45, 13-19, 2018
  27. ★, Elucidation of the inflammatory mechanism of mandibular cartilage development and the establishment of a prevention method for PCR using Sema3A, Impact, 3(4), 67-69, 2019
  28. Protective effects of cilengitide on inflammation in chondrocytes under excessive mechanical stress, CELL BIOLOGY INTERNATIONAL, 44(4), 966-974, 20200401
    Link to Paper Search Results by DOI
  29. High-Frequency Near-Infrared Diode Laser Irradiation Attenuates IL-1 beta-Induced Expression of Inflammatory Cytokines and Matrix Metalloproteinases in Human Primary Chondrocytes, JOURNAL OF CLINICAL MEDICINE, 9(3), 20200301
    Link to Paper Search Results by DOI
  30. IL-1beta in the trigeminal subnucleus caudalis contributes to extra-territorial allodynia/hyperalgesia following a trigeminal nerve injury., 15(467), 1-14, 2011
  31. Angle Orthodontist,, 78, 1110-1118, 2008
  32. ANGPTL2 Promotes Inflammation via Integrin a5b1 in Chondrocytes, Cartilage, 20190101
  33. ★, FAK inhibition protects condylar cartilage under excessive mechanical stress, Oral Diseases, 2020
  34. ★, Orthodontic Treatment Combined with Miniscrew Anchorage for an Angle Class II Division 1 Case with Severe Crowding and TMDs, 3(3), 20200826
  35. Examination of the effect of combined use of Er:YAG laser irradiation and mechanical force loading on bone metabolism using primary human gingival fibroblasts, LASERS IN MEDICAL SCIENCE, 35(9), 2059-2064, 20201220
    Link to Paper Search Results by DOI
  36. ANGPTL2 Induces Synovial Inflammation via LILRB2, INFLAMMATION, 44(3), 1108-1118, 20210601
    Link to Paper Search Results by DOI
  37. ANGPTL2 Promotes Inflammation via Integrin alpha 5 beta 1 in Chondrocytes, CARTILAGE, 13(2_SUPPL), 885S-897S, 202112
    Link to Paper Search Results by DOI

Invited Lecture, Oral Presentation, Poster Presentation

  1. Role of Semaphorin3A in endochondral ossification of mandibular condyle, Tsuboi E., Asakawa Y., Hirose N., Yanoshita M., Takano M., Nishiyama S., Kubo N., Onishi A., Yamauchi Y., Tanimoto K, The 9th International Orthodontic Congress, The 12th Asian Pacific Orthodontic Congress, The 79th Annual Meeting of the Japanese Orthodontic Society, 2020/10/04, With Invitation, English, Japanese orthodontic sosiety
  2. The difference of cephalometric features between the past and present Japanese adults with normal occlusion, Yamauchi Y., Hirose N., Yanoshita M., Onishi A., Takano M., Nishiyama S., Kagawa H., Tsuboi E., Kubo N., Tanimoto K, The 9th International Orthodontic Congress, The 12th Asian Pacific Orthodontic Congress, The 79th Annual Meeting of the Japanese Orthodontic Society (, 2020/10/04, With Invitation, English, Japanese orthodontic society
  3. Oral and maxillofacial features of 3 rare congenital diseases uncovered by the Japanese National Health Insurance, Onishi A., Hirose N., Yamauchi Y., Yanoshita M., Takano M., Nishiyama S., Kagawa H., Tsuboi E., Kubo N., Tanimoto K, The 9th International Orthodontic Congress, The 12th Asian Pacific Orthodontic Congress, The 79th Annual Meeting of the Japanese Orthodontic Society, 2020/10/04, Without Invitation, English, Japanese orthodontic sosiety
  4. Familial cases with Hyper-IgE syndrome, Oral/maxillofacial features and Orthodontic treatment plan, Yanoshita M., Hirose N., Takano M., Onishi A., Yamauchi Y., Nishiyama S., Kagawa H., Tsuboi E., Kubo N., Asakawa Y., Tanimoto K, The 9th International Orthodontic Congress, The 12th Asian Pacific Orthodontic Congress, The 79th Annual Meeting of the Japanese Orthodontic Society, 2020/10/04, Without Invitation, English, Japanese orthodontic society
  5. An open bite case with temporomandibular disorders caused by a car accident ; a case report, Hirose N., Yanoshita M., Onishi A., Yamauchi Y., Nishiyama S., Takano M., Tsuboi E., Kubo N., Tanimoto K., The 9th International Orthodontic Congress, The 12th Asian Pacific Orthodontic Congress, The 79th Annual Meeting of the Japanese Orthodontic Society, 2020/10/04, Without Invitation, English, Japanese Orthodontic Society
  6. Changes in maxillofacial morphology in normal occlusion of Japanese adult, Yamauchi Y., Hirose N., Yanoshita M., Onishi A., Nishiyama S., Kagawa H., Kubo N., Yoshimi Y., Tanimoto K, The 59th Hiroshima Prefectural Dental Association, The 104th Hiroshima University Dental Society, 2020/11/15, Without Invitation, Japanese
  7. Effects of amelogenin on the metabolism of human osteoblast-like cells―Development of bone regeneration therapy using the peptide derived from enamel protein―:, Awada T.,Kunimatsu R.,Yoshimi Y.,Hirose N.,Kojima S.,Kaku M.,Hirata I.,Kato K.,Tanne K.,Tanimoto K, 2014, Without Invitation, Japanese
  8. Role of mechanoreceptor in the metabolism of chondrocytes under excessive mechanical stimuli, Okamoto Y., Asakawa Y., Shirakura M.,Kunimatsu R.,Hirose N.,Mitsuyoshi T.,Su S., Tanne K.,Tanimoto K., Okamoto Y., Asakawa Y., Shirakura M.,Kunimatsu R.,Hirose N.,Mitsuyoshi T.,Su S., Tanne K.,Tanimoto K., The 27th Annual Meeting of The Japanese Society for Temporomandibular Joint(Fukuoka), 2014., 2014, Without Invitation, Japanese
  9. Effects of Matrix degradation via EP4 receptor in condylar chondrocytes under excessive mechanical stress., Mitsuyoshi T, SU Shaoching, Asakawa Y, Hirose N, Awada T, Okamoto Y, Tanne K and Tanimoto K.:, The 27th Annual Meeting of the Society for the Temporomandibular Joint(Fukuoka),, 2014, Without Invitation, Japanese
  10. A case report of CHARGE syndrome with cleft plate and bimaxillary hypoplasia:, Yuko Nakao, Myongsun Koh, Tomomi Date, Kayo Horie, Yu Matsumura, Naoto Hirose, Hiroshi Ueda, Kotaro Tanimoto., 57th Annual Meeting of Chu-Shikoku Orthodontic Society（Yamaguchi）,2014., 2014, Without Invitation, Japanese
  11. Evaluation of orthodontic treatment for twins with or without tooth extraction:, 2014, Without Invitation, Japanese
  12. Evaluation of the cleaning effect of the tooth surface by use of nano particks from shell:, Kunimatsu R., Sumi K., Asakawa Y., Hirose N., Mitsuyoshi T., Yoshimi Y., Gunji H, The 73th Annual Meeting of the Japanese Orthodontic Society (Makuhari), 2014., 2014, Without Invitation, Japanese
  13. Effects of Er;YAG laser during experimental tooth movement：, Without Invitation, Japanese
  14. A crowding case with an upper central incisor presenting substitutional root resorption treated with auto-transplantation, Date T., Myongsun Koh M., Horie K., Matsumura Y., Nakao Y., Yanoshita M., Hirose N., Ueda H., Tanne K., Tanimoto K, 2014, Without Invitation, English
  15. Functional mechanism of Integrin as mechanoreceptor in the metabolism of chondrocytes under excessive mechanical stress:, Okamoto Y., Asakawa-Tanne Y., Kunimatsu R., Hirose N., Mitsuyoshi T., Tanne K., Tanimoto K.:, The 47th Annual Scientific Congress of Korean Association of Orthodontists(Seoul),2014., 2014, Without Invitation, English
  16. Role of mechanoreceptor in the metabolism of chondrocytes under excessive mechanical stimuli:, Okamoto Y., Asakawa Y., Shirakura M., Kunimatsu R., Hirose N., Mitsuyoshi T., Su S., Irome K., Tanne K., Tanimoto K.juvenile idiopathic arthritis (JIA)(Tampere Finland), 2014., The 6th EuroTMjoint Congress on temporomandibular joint (TMJ) in juvenile idiopathic arthritis (JIA)(Tampere Finland), 2014., 2014, Without Invitation, English
  17. Role of mechanoreceptor in the metabolism of chondrocytes under excessive mechanical stimuli:, Okamoto Y., Asakawa Y., Shirakura M.,Kunimatsu R.,Hirose N.,Mitsuyoshi T.,Su S., Tanne K.,Tanimoto K.:, The 47th Annual Meeting of the Hiroshima University Dental Society(Hiroshima), 2014., 2014, Without Invitation, English
  18. Amelogenin variants promote the proliferation and differentiation of human cementoblasts;, Yoshimi Y., Tanimoto K., Kunimatsu R., Hirose N., Tanne K.: 113th Annual Session of American Association of Orthodontists (Philadelphia), 2013., 113th Annual Session of American Association of Orthodontists (Philadelphia), 2013., Without Invitation, English
  19. Effect of Celecoxib on extracellular matrix metabolism in condylar chondrocytes under excessive mechanical stress:, Su S.C., Tanimoto K., Tanne Y., Hirose N., Mitsuyoshi T., Tanne K.:, The 26th Annual Meeting of the Japanese Society for the Temporomandibular Joint (Tokyo), 2013., 46th Korean Association of Orthodontists (Jeju), 2013., 2013, Without Invitation, English
  20. Effects of C-terminal amelogenin on the metabolism of human osteoblast- like cells:, Awada T., Kunimatsu R., Hirose N., Yoshimi Y., Tanne Y., Hirata I., Kato K., Tanne K., Tanimoto K., 46th Korean Association of Orthodontists (Jeju), 2013., 2013, Without Invitation, English
  21. Application of human recombinant amelogenin to regeneration of cementum:, Kunimatsu R., Tanimoto K., Tanne Y., Hirose N., Yoshimi Y., Miyauchi M., Takata T., Tanne K, The 46 Korean Association Orthodontists (Jeju), 2013., 2013, Without Invitation, English
  22. Amelogenin-guided biomineralization of hydroxyapatite crystal on tooth enamel:, Tanimoto K., Kunimatsu R., Tanne Y., Hirose N., Yoshimi Y., Sumi K., Tanne K: The 46th Korean Association Orthodontists (Jeju), 2013., The 46th Korean Association Orthodontists (Jeju), 2013., 2013, Without Invitation, English
  23. The analysis and evaluation after orthodontic treatment for twins (extraction and non-extraction cases):, Taiwan Association of Orthodontists' Annual Meeting (Taiwan), 2013., 2013, Without Invitation, English
  24. Effect of celecoxib on extracellular matrix metabolism in condylar chondrocytes under excessive mechanical stress: ., Su S.C., Tanne Y., Hirose N., Mitsuyoshi T., Okamoto Y., Tanne K., Tanimoto K.:, 25th Taiwan Association of Orthodontists Annual Conference (Kaohsiung), 2013., 2013, Without Invitation, English
  25. A case of temporomandibular disorder with occlusal disharmony caused by an inappropriate use of splint, Naoto Hirose, Makoto Yanoshita, Mami Takano, Chikako Sumi, Yuki Okamoto, Tetsuya Awada, Yuki Asakawa, Kotaro Tanimoto, 2016, Without Invitation, Japanese, Hakone, Kanagawa
  26. 広島大学病院矯正歯科における先天性疾患患者に関する統計学調査, 2015/07/05, Without Invitation, Japanese, Takamatsu, Japan
  27. Clinical investigation into patients with Angle Class I malocclucion by the Orthodontics Department of Hiroshima University Hospital, Sumi C.,Ueda H.,Hiose N.,Sumi H.,Tanimoto K., 2015/12/04, Without Invitation, English
  28. An orthodontic case report of a skeletal Class II patient with temporomandibular disorder, mandibular recession and open bite, Naoto Hirose., Yu Matsumura., Chikako Sumi., Cynthia Concepcion., Makoto Yanoshita., Hiroshi Ueda., Kotaro Tanimoto, .: 8th International Orthodontic Congress(London), 2015., 2015/09/27, Without Invitation, English, World federation of orthodontis
  29. Amelogenin isoforms effect the proliferation in human periodontal tissue cells:, Yoshimi Y., Kunimatsu R., Hirose N., Awada T., Mitsuyoshi T., Gunji H., Takata T., Tanne K., Tanimoto T.:, 8th International orthodontic congress (London), 2015., 2015/09/27, Without Invitation, English, WFO
  30. Effects of Low molecular weight hyaluronan on the expression of PRG4 through CD44 in synovial membrane cells, Mitsuyoshi T, Asakawa Y , Hirose N, Okamoto Y, Yanoshita M, Tanne k, Tanimoto K, ..: 8th international orthodontic congress(London), 2015., 2015/09/27, Without Invitation, English, WFO
  31. Amelogenin variants increased the proliferation of HCEM through the MAPK-ERK signaling pathway, Yoshimi Y., Kunimatsu R., Awada T., Hirose N., Mitsuyoshi T., Sumi K., Gunji H., Nakajima K., Kimura A., Miyauchi M., Takata T., Tanimoto K.:, The 74th Annual Meeting of the Japanese Orthodontic Society (Fukuoka), 2015., 2015/11/08, Without Invitation, English
  32. Effects of human full length amelogenin on the proliferation of human osteoblasts:, Kunimatsu R., Yoshimi Y., Awada T., Asakawa Y., Hirose N., Mitsuyoshi T., Sumi K., Gunji H., Tsuka Y., Tanne K., Tanimoto K, .: The 74th Annual Meeting of the Japanese Orthodontic Society (Fukuoka), 2015., 2015/11/08, Without Invitation, English, Fukuoka
  33. 　 Elucidation of the inflammation promoted by ANGPTL2 in excessive mechanical loading on chondrocytes:, 2017/07/29, Without Invitation, Japanese, published
  34. Effects of FAK inhibitor on condylar cartilage under the excessive mechanical stress., ：Yanoshita M., Hirose N., Sumi C., Takano M., Nishiyama S., Tanimoto K, The 57th Hiroshima Prefecture Dental Association, The 102th Hiroshima University Dental Society (Hiroshima), 2018/06/22, Without Invitation, Japanese, hiroshima
  35. The role of Semaphorin3A in chondrocyte, ：Sumi C., Hirose N., Yanoshita M., Takano M., Nishiyama S., Tsuboi E., Asakawa Y., Tanimoto K, The 77th Annual Meeting of the Japanese Orthodontic Society (Yokohama), 2018/10/30, Without Invitation, Japanese
  36. Effects of FAK inhibitor on condylar cartilage under the excessive mechanical stress, Yanoshita M., Hirose N., Sumi C., Takano M., Nishiyama S., Tanimoto K, The 77th Annual Meeting of the Japanese Orthodontic Society (Yokohama),, 2018/10/30, Without Invitation, Japanese
  37. New therapeutic medicines for temporomandibular joint disorders, Chikako Sumi, Naoto hirose, Orthodontic Seminar in Hiroshima, 2018/04/16, Without Invitation, Japanese, hiroshima
  38. Evaluation of oral function before and after orthognathic surgery~ by use of EPG~, Naoto Hirose, 2019/06/09, With Invitation, Japanese
  39. Semaphorin3A Inhibits inflammation in Chondrocytes under Excessive Mechanical Stress, Naoto Hirose, Chikako sumi, Makoto Yanoshita, Sayuri Nishiyama, Eri Tsuboi, Azusa onishi, Yuka Yamauchi, Yuki Asakawa, Kotaro Tanimoto, IADR(iadr international association for dental research) Annual meeting, 2019/06/19, Without Invitation, English, IADR(iadr international association for dental research)
  40. ANGPTL2 promotes inflammation in chondrocytes, 2019/07/27, Without Invitation, Japanese

Awards

  1. award of Japanese orthodontic society, Longitudinal effects of estrogen on mandibular growth and changes in cartilage during the growth period in rats
  2. 2012, 2012, Best poster presentation award, Korean Association of Orthodontists, Ameloblastin regulates proliferation and differentiation of ameloblasts and maintains morphology
    Related URL
  3. 2013, the 26 th Japanese society of osteoarthritis cartilage best award ishibashi, 日本顎関節学会, Effect of Celecoxib on extracellular matrix metabolism in condylar chondrocytes under excessive mechanical stress
  4. 2014, The 47th Annual Scientific Congress of Korean Association of Orthodontists(Seoul), 2014., ＫＡＯ, Functional mechanism of Integrin as mechanoreceptor in the metabolism of chondrocytes under excessive mechanical stress
  5. 2014, 47th hiroshima university dentistry congress encouragingprize, Role of mechanoreceptor in the metabolism of chondrocytes under excessivemechanical stimuli
  6. 2012, poster presentation award, The 45th Scientific Congress of Korean Association of Orthodontists 4th Joint Symposium of KAO and JOS (Seoul), 2012., TNF-α in the trigeminal subnucleus caudalis contributes to extra- territorial allodynia/hyperalgesia following a trigeminal nerve injur

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI, 2014, 2015
    Permalink
  2. KAKENHI, Elucidation of the mechanism ameloblastin upregulates formation of tooth root, and application to the treatment of root resorption, 2012, 2013
    Permalink
  3. KAKENHI, Elucidation of condylar cartilage resorption mechanism in TMJ-osteoarthritis and search of a new regulatory factor., 2011, 2013
    Permalink
  4. KAKENHI, 2016, 2018
  5. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2019, 2021

Social Activities

Organizing Academic Conferences, etc.

  1. angle society, 2018/04, 2019/03

History as Peer Reviews of Academic Papers

  1. 2024, Oral and Maxillofacial Surgery, Others, Reviewer, 1
  2. 2023, Scientific reports, Others, reviewer, 1
  3. 2023, European Journal of Oral Sciences, Others, reviewer, 1
  4. 2017, cell proliferation, Editor, 1
  5. 2018, Cellular and Molecular Life Sciences, Editor, 1
  6. 2018, Cellular Physiology and Biochemistry, Editor, 1
  7. 2018, Frontiers in Pharmacology, Editor, Reviewer, 1
  8. 2019, pharmacology, Editor, Reviewer, 1
  9. 2019, Clinical and Experimental Pharmacology and Physiology, Editor
  10. 2019, Oxidative Medicine and Cellular Longevity, Editor, reviewer, 1