Hideki Hanada

Last Updated :2025/07/05

Affiliations, Positions
Amphibian Research Center, Assistant Professor
E-mail
hanadahiroshima-u.ac.jp

Basic Information

Major Professional Backgrounds

  • 1990/04/01, 2000/03/31, Hiroshima University, Faculty of Science, Institute for Amphibian Biology, -
  • 2000/04/01, 2007/03/31, Hiroshima University, Graduate School of Science, Institute for Amphibian Biology, -
  • 2007/04/01, 2016/09/30, Hiroshima University, Graduate School of Science, Institute for Amphibian Biology, Assistant Professor

Academic Degrees

  • Doctor of Philosophy in Medical Science, Okayama University
  • Master of Education, Fukuoka University of Education

Research Fields

  • Biology;Basic biology;Genetics / Chromosome dynamics

Educational Activity

Course in Charge

  1. 2025, Liberal Arts Education Program1, 3Term, The life science of amphibians
  2. 2025, Undergraduate Education, 1Term, Endocrinology・Immunology
  3. 2025, Undergraduate Education, Second Semester, Seminar for Amphibian Biology
  4. 2025, Undergraduate Education, First Semester, Practice for Fundamental Biology I
  5. 2025, Undergraduate Education, Second Semester, Practice for Fundamental Biology II
  6. 2025, Undergraduate Education, Second Semester, Practice for Fundamental Biology IV
  7. 2025, Undergraduate Education, First Semester, Practice for Fundamental Biology IV
  8. 2025, Graduate Education (Master's Program) , 3Term, Natural History Sciences

Research Activities

Academic Papers

  1. Anticancer agent doxorubicin toxicity to in vitro X. laevis tadpole organ heart and mature frog heart and liver mitochondria, The Journal of Toxicological Sciences, 50(7), 2025
  2. Long-term Xenopus laevis tadpole -heart-organ-culture: Physiological changes in cholinergic and adrenergic sensitivities of tadpole heart with thyroxine-treatment, CURRENT RESEARCH IN PHYSIOLOGY, 6, 2023
    Link to Paper Search Results by DOI
  3. Amiodarone bioconcentration and suppression of metamorphosis in Xenopus., Aquatic Toxicology, 228(228), 105623, 2020
  4. Dl-a-tocopherol enhances the herbicide 1,1 '-dimetyl-4,4 '-bipyridium dichloride (paraquat, PQ) genotoxicity in cultured anuran leukocytes, HEREDITAS, 148(4-5), 118-124, 201111
    Link to Paper Search Results by DOI
  5. Strong expression of the calreticulin gene in the liver of Rana rugosa tadpoles, but not adult frogs, Journal of Experimental Zoology, 275(4), 431-443, 19960401
  6. Alteration of the sex determining system resulting from structural change of the sex chromosomes in the frog Rana rugosa., Journal of Experimental Zoology, 286(3), 313-319, 20000201
  7. Comparison of catalase in diploid and haploid Rana rugosa using heat and chemical inactivation techniques, Comparative Biochemistry and Physiology, B118(3), 499-503, 19970401
  8. Evidence for two successive pericentric inversions in sex lampbrush chromosomes of Rana rugosa (Anura: Ranidae), Chromosoma, 106, 178-182, 19970401
  9. Thyroxine enhancement and the role of reactive oxygen species in tadpole tail apoptosis, Free Radical Biology and Medicine, 26, 1001-1009, 19990401
  10. Reactive oxygen species and the mechanism for tail apoptosis in Rana rugosa and Rana japonica, Comparative Biochemistry and Physiology part A, 1, 51-66, 20000401
  11. Do reactive oxygen species underlie the mechanism of apoptosis in the tadpole tail?, Free Radical Biology and Medicine, 23(2), 294-301, 19970401
  12. Inhibitor and temperature effect on catalase in the liver of adult diploid and haploid Rana rugosa, Comparative Biochemistry and Physiology, B119, 235-239, 19970401
  13. Structural differences between XX and ZW sex lampbrush chromosomes in Rana rugosa females (Anura: Ranidae), Chromosoma, 105(4), 237-241, 19960401
  14. Four kinds of sex chromosomes in Rana rugosa, Scientific Report of the Laboratory for Amphibian Biology= Hiroshima University, 13, 1-34, 19940401
  15. Sex of reciprocal hybrids between the Hamakita (XX-XY type) population and the Murakami (ZW- ZZ type) population in Rana rugosa, Scientific Report of the Laboratory for Amphibian Biology, Hiroshima University, 13, 35-50, 19940101
  16. G and C banding show structural differences between the Z and W chromosomes in the frog Buergeria buergeri, Hereditas, 136, 151-154, 20020401
  17. An investigation into the role of reactive oxygen species in tadpole tail apoptosis by means of thyroxine enhancement, IBC's Fifth Annual Conference on Apoptosis, International Business Communications, 281, 19980401
  18. Evidence for heteromorphic sex chromosomes in males of Rana tagoi and Rana sakuraii in Nishitama district of Tokyo (Anura: Ranidae), Chromosome Research, 7, 31-42, 19990401
  19. Effects of high gravity on amphibian development, Biological Sciences in Space, 17, 215-216, 20030401
  20. Anti-thyroid hormonal activity of tetrabrmobisphenol A, a flame retardant, and related compounds: affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis, Life Science, 76, 1589-1601, 20050401
  21. Development of metamorphosis assay using Silurana tropicalis for the detection of thyroid system-disrupting chemicals, Ecotoxicology and Environmental Safety, 64, 281-287, 20060401
  22. Xenopus tropicalis: An Ideal Experimental Animal in Amphibia, Experimental Animals, 59(4), 395, 20100701
  23. Alteration of the sex determining system resulting from structural change of the sex chromosomes in the frog Rana rugosa, JOURNAL OF EXPERIMENTAL ZOOLOGY, 286(3), 313-319, 20000215
    Link to Paper Search Results by DOI
  24. Cyclosporin A inhibits thyroid hormone-induced shortening of the tadpole tail through membrane permeability transition, COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 135(3), 473-483, 200307
    Link to Paper Search Results by DOI
  25. Development of metamorphosis assay using Silurana tropicalis for the detection of thyroid system-disrupting chemicals, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 64(3), 281-287, 200607
    Link to Paper Search Results by DOI
  26. Effects of endocrine disrupting chemicals on amphibian metamorphosis and mitochondrial membrane permeability transition, JOURNAL OF HEALTH SCIENCE, 54(3), 273-280, 200806
    Link to Paper Search Results by DOI
  27. Disruption of Thyroid Hormone Function by Environmental Pollutants, JOURNAL OF HEALTH SCIENCE, 55(2), 147-160, 200904
    Link to Paper Search Results by DOI
  28. Acetyl-L-carnitine suppresses thyroid hormone-induced and spontaneous anuran tadpole tail shortening, HEREDITAS, 150(1), 1-9, 201302
    Link to Paper Search Results by DOI
  29. Developmental changes in drug-metabolizing enzyme expression during metamorphosis of Xenopus tropicalis, JOURNAL OF TOXICOLOGICAL SCIENCES, 42(5), 605-613, 201710
  30. Amiodarone bioconcentration and suppression of metamorphosis in Xenopus, AQUATIC TOXICOLOGY, 228, 202011
    Link to Paper Search Results by DOI
  31. Xenopus tropicalis: An Ideal Experimental Animal in Amphibia, Proceedings of The Japanese Society of Animal Models for Human Diseases, 59(4), 395-405, 2010
  32. Dl-α-tocopherol enhances the herbicide 1,1'-dimetyl-4,4'-bipyridium dichloride (paraquat, PQ) genotoxicity in cultured anuran leukocytes., Dl-α-tocopherol enhances the herbicide 1,1'-dimetyl-4,4'-bipyridium dichloride (paraquat, PQ) genotoxicity in cultured anuran leukocytes., 148(4-5), 2011
  33. G and C banding show structural differences between the Z and W chromosomes in the frog Buergeria buergeri., G and C banding show structural differences between the Z and W chromosomes in the frog Buergeria buergeri., 136(2), 2002
  34. Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis., Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis., 76(14), 2005
  35. Effects of high gravity on amphibian development., Effects of high gravity on amphibian development., 17(3), 2003
  36. Phenolic antioxidant 2,6-di-tert-butyl-p-cresol (vitamin E synthetic analogue) does not inhibit 1,1'-dimetyl-4,4'-bipyridium dichloride (paraquat)-induced structural chromosomal damage in cultured leukocytes of the dark-spotted-frog Pelophylax (Rana) nigromaculatus., Phenolic antioxidant 2,6-di-tert-butyl-p-cresol (vitamin E synthetic analogue) does not inhibit 1,1'-dimetyl-4,4'-bipyridium dichloride (paraquat)-induced structural chromosomal damage in cultured leukocytes of the dark-spotted-frog Pelophylax (Rana) nigromaculatus., 149(5), 2012

Publications such as books

  1. 1998, An investigation into the role of reactive oxygen species in tadpole tail apoptosis by means of thyroxine enhancement , IBC’s Fifth Annual Conference on Apoptosis, 1998, Report
  2. 1998, 生命誕生と生物の生存戦略 , 1998, Scholarly Book