HIDEKI ITO

Last Updated :2025/04/02

Affiliations, Positions
Hiroshima University Hospital(Patient Support Center), Professor
E-mail
itohhidehiroshima-u.ac.jp

Basic Information

Major Professional Backgrounds

  • 2019/08, Hiroshima University Hospital, Professor
  • 2017/07, Shiga University of Medical Science, Associate professor
  • 2016/07, Shiga University of Medical Science, Associate professor
  • 2012/07, Shiga University of Medical Science, Assistant professor
  • 2011/02, France Sorbonne Universites, UPMC Univ Paris 06, UMR_S1166, Researcher
  • 2007/04, Shiga University of Medical Science, Assistant professor
  • 2006/04, Shiga University of Medical Science, Assistant professor
  • 2005/04, Yasu Hospital, Director
  • 2004/04, Ishikawa Prefectural Central Hospital, Head Physician
  • 2003/04, NIPS, Postdoctoral Researcher
  • 2002/04, Takaoka City Hospital, Doctor
  • 2001/04, Fukui Cardiovascular Center, Doctor
  • 2000/11, Kanazawa University Hospital, Doctor
  • 2000/04, Kanazawa Cardiovascular Hospital, Clinical fellow
  • 1999/04, Saiseikai Kanazawa Hospital, Doctor
  • 1998/04, Kanazawa Universiy Hospital, Doctor
  • 1997/04, Keiju Medical Center, Doctor
  • 1996/04, Kanazawa University Hospital, medical intern

Educational Backgrounds

  • Kanazawa University, 1996
  • Kanazawa University Graduate School of Medical Sciences, 2002

Academic Degrees

  • Kanazawa University

Research Activities

Academic Papers

  1. CTG repeat length underlying cardiac events and sudden death in myotonic dystrophy type 1, Eur Heart J Open, 2024
    Link to Paper Search Results by DOI
  2. Novel KCNQ1 Q234K variant, identified in patients with long QT syndrome and epileptiform activity, induces both gain- and loss-of-function of slowly activating delayed rectifier potassium currents, FRONTIERS IN PHYSIOLOGY, 15, 20240719
    Link to Paper Search Results by DOI
  3. Clinical characterization of type 1 long QT syndrome caused by C-terminus Kv7.1 variants, HEART RHYTHM, 21(7), 1113-1120, 202407
    Link to Paper Search Results by DOI
  4. A Clinical Trial Evaluating the Efficacy of Deep Learning-Based Facial Recognition for Patient Identification in Diverse Hospital Settings, BIOENGINEERING-BASEL, 11(4), 202404
    Link to Paper Search Results by DOI
  5. Efficacy and Tolerability of Ivabradine for Cardiomyopathy in Patients with Duchenne Muscular Dystrophy One Year Treatment Results in Japanese National Hospitals, INTERNATIONAL HEART JOURNAL, 65(2), 211-217, 202403
    Link to Paper Search Results by DOI
  6. Novel CACNA1C R511Q mutation, located in domain I-II linker, causes non-syndromic type-8 long QT syndrome, PLOS ONE, 17(7), 20220721
    Link to Paper Search Results by DOI
  7. JCS/JHRS 2020 Guideline on Pharmacotherapy of Cardiac Arrhythmias, JOURNAL OF ARRHYTHMIA, 38(6), 833-973, 202212
    Link to Paper Search Results by DOI
  8. JCS/JHRS 2020 Guideline on Pharmacotherapy of Cardiac Arrhythmias, CIRCULATION JOURNAL, 86(11), 1790-1924, 202211
    Link to Paper Search Results by DOI
  9. Novel CALM3 Variant Causing Calmodulinopathy With Variable Expressivity in a 4-Generation Family, CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 15(3), 202203
    Link to Paper Search Results by DOI
  10. Sudden death after inappropriate shocks of implantable cardioverter defibrillator in a catecholaminergic polymorphic ventricular tachycardia case with a novel RyR2 mutation, JOURNAL OF ELECTROCARDIOLOGY, 69, 111-118, 2021
    Link to Paper Search Results by DOI
  11. Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls, GENETICS IN MEDICINE, 23(1), 47-58, 202101
    Link to Paper Search Results by DOI
  12. Differences in Pharmaceutical Intervention Triggers for the Optimization of Medication by Patient Age: A University Hospital Study, BIOLOGICAL & PHARMACEUTICAL BULLETIN, 44(8), 1060-1066, 202108
    Link to Paper Search Results by DOI
  13. High incidence of major bleeding with off-label use of edoxaban, JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 69(3), 311-316, 202111
    Link to Paper Search Results by DOI
  14. Cardiac conduction disorders as markers of cardiac events in myotonic dystrophy type 1, JAHA: Journal of the American Heart Association, 2020
  15. A computational analysis of the effect of sevoflurane in a human ventricular cell model of long QT syndrome: Importance of repolarization reserve in the QT-prolonging effect of sevoflurane, EUROPEAN JOURNAL OF PHARMACOLOGY, 883, 20200915
    Link to Paper Search Results by DOI
  16. The genetics underlying acquired long QT syndrome. Impact for genetic screening., Eur Heart J, 37(18), 1456-1464, 2016
  17. Splicing misregulation of SCN5A contributes to cardiac conduction delay and heart arrhythmia in myotonic dystrophy., Nat Commun, 7, 11067, 2016
  18. A Kir3.4 mutation causes Andersen–Tawil syndrome by an inhibitory effect on Kir2.1., Neurology, 82(12), 1058-1064, 2014
  19. Aortopulmonary artery dissection, J Am Coll Cardiol, 54(21), 1990, 2009
  20. Latent genetic backgrounds and molecular pathogenesis in drug-induced long-QT syndrome., Circulation Arrhythmia Electrophysiology, 2(5), 511-523, 2009
  21. D85N, a KCNE1 polymorphism, is a disease-causing gene variant in long QT syndrome., J Am Coll Cardiol, 54(9), 812-819, 2009
  22. Clinical features of hypertrophic cardiomyopathy caused by a Lys183 deletion mutation in the cardiac troponin I gene., Circulation, 102(6), 663-669, 2000
  23. A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation., J Am Coll Cardiol, 52(16), 1326-1334, 2008
  24. The E1784K mutation in SCN5A is associated with mixed clinical phenotype of type 3 long QT syndrome., J Clin Invest, 118(6), 2219-2229, 2008
  25. A novel gain-of-function KCNJ2 mutation associated with short-QT syndrome impairs inward rectification of Kir2.1 currents., Cardiovasc Res, 93(4), 666-673, 2012
  26. Identification of a KCNQ1 polymorphism acting as a protective modifier against arrhythmic risk in long-QT syndrome., Circulation Cardiovascular Genetics, 6(4), 354-361, 2013
  27. Population Pharmacokinetics and Pharmacodynamics of Apixaban Linking Its Plasma Concentration to Intrinsic Activated Coagulation Factor X Activity in Japanese Patients with Atrial Fibrillation., AAPS J, 21(5), 80, 2019
  28. Population pharmacokinetics and pharmacogenomics of apixaban in Japanese adult patients with atrial fibrillation., Br J Clin Pharmacol, 84(6), 1301-1312, 2018
  29. A hERG mutation E1039X produced a synergistic lesion on IKs together with KCNQ1-R174C mutation in a LQTS family with three compound mutations., Sci Rep, 8(1), 21442-21446, 2018
  30. A challenge for mutation specific risk stratification in long QT syndrome type 1., J Cardiol, 72(1), 56-65, 2018
  31. Bradycardia Is a Specific Phenotype of Catecholaminergic Polymorphic Ventricular Tachycardia Induced by RYR2 Mutations., Intern Med, 57(13), 1813-1817, 2018
  32. Novel intracellular transport-refractory mutations in KCNH2 identified in patients with symptomatic long QT syndrome., J Cardiol, 71(4), 401-408, 2018
  33. Impact of ABCB1, ABCG2, and CYP3A5 polymorphisms on plasma trough concentrations of apixaban in Japanese patients with atrial fibrillation., Pharmacogenet Genomics, 27(9), 329-336, 2017
  34. Drug-induced fatal arrhythmias: Acquired long QT and Brugada syndromes., Pharmacol Ther, 176, 48-59, 2017
  35. Arrhythmia risk and β-blocker therapy in pregnant women with long QT syndrome., Heart, 103(17), 1374-1379, 2017
  36. Contribution of a KCNH2 variant in genotyped long QT syndrome: Romano-Ward syndrome under double mutations and acquired long QT syndrome under heterozygote., J Cardiol, 70(1), 74-79, 2017
  37. Phenotypic Variability of ANK2 Mutations in Patients With Inherited Primary Arrhythmia Syndromes., Circ J, 80(12), 2435-2442, 2016
  38. Patient-Specific Human Induced Pluripotent Stem Cell Model Assessed with Electrical Pacing Validates S107 as a Potential Therapeutic Agent for Catecholaminergic Polymorphic Ventricular Tachycardia., PLoS One, 11(10), e0164795, 2016
  39. A type 2 ryanodine receptor variant associated with reduced Ca2+ release and short-coupled torsades de pointes ventricular arrhythmia., Heart Rhythm, 14(1), 98-107, 2017
  40. A Novel SCN5A Mutation Associated with Drug Induced Brugada Type ECG., PLoS One, 11(8), e0161872, 2016
  41. Early repolarization and risk of arrhythmia events in long QT syndrome., Int J Cardiol, 223, 540-542, 2016
  42. Impact of Updated Diagnostic Criteria for Long QT Syndrome on Clinical Detection of Diseased Patients: Results From a Study of Patients Carrying Gene Mutations., JACC Clin Electrophysiol, 2(3), 279-287, 2016
  43. Practical applicability of landiolol, an ultra-short-acting β1-selective blocker, for rapid atrial and ventricular tachyarrhythmias with left ventricular dysfunction., J Arrhythm, 32(2), 82-88, 2016
  44. Multigenerational Inheritance of Long QT Syndrome Type 2 in a Japanese Family., Intern Med., 55(3), 259-262, 2016
  45. Pediatric Cohort With Long QT Syndrome- KCNH2 Mutation Carriers Present Late Onset But Severe Symptoms., Circ J, 80(3), 696-702, 2016
  46. Asymmetry of parental origin in long QT syndrome: preferential maternal transmission of KCNQ1 variants linked to channel dysfunction., Eur J Hum Genet, 24(8), 1160-1166, 2016
  47. Löffler Endocarditis and Lacking Heart., Intern Med, 54(23), 3093, 2015
  48. A Common Mutation of Long QT Syndrome Type 1 in Japan., Circ J, 79(9), 2026-2030, 2015
  49. Long-term pharmacological therapy of Brugada syndrome: is J-wave attenuation a marker of drug efficacy?, Intern Med, 53(14), 1523-1526, 2014
  50. Long QT syndrome type 8: novel CACNA1C mutations causing QT prolongation and variant phenotypes., Europace, 16(12), 1828-1837, 2014
  51. Mosaic KCNJ2 mutation in Andersen-Tawil syndrome: targeted deep sequencing is useful for the detection of mosaicism., Clin Genet, 87(3), 279-283, 2015
  52. Gain-of-function KCNH2 mutations in patients with Brugada syndrome., J Cardiovasc Electrophysiol, 25(5), 522-530, 2014
  53. Exon 3 deletion of RYR2 encoding cardiac ryanodine receptor is associated with left ventricular non-compaction., Europace, 16(11), 1646-1654, 2014
  54. Nonsense-mediated mRNA decay due to a CACNA1C splicing mutation in a patient with Brugada syndrome., Heart Rhythm, 11(4), 629-634, 2014
  55. Cardiac channelopathies associated with infantile fatal ventricular arrhythmias: from the cradle to the bench., J Cardiovasc Electrophysiol, 25(1), 66-73, 2014
  56. A novel KCNQ1 missense mutation identified in a patient with juvenile-onset atrial fibrillation causes constitutively open IKs channels., Heart Rhythm, 11(1), 67-75, 2014
  57. Genetic background of catecholaminergic polymorphic ventricular tachycardia in Japan., Circ J, 77(7), 1705-1713, 2013
  58. L-type calcium channel mutations in Japanese patients with inherited arrhythmias., Circ J, 77(7), 1799-1806, 2013
  59. Age-dependent clinical and genetic characteristics in Japanese patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia., Circ J, 77(6), 1534-1542, 2013
  60. Seasonal and circadian distributions of cardiac events in genotyped patients with congenital long QT syndrome., Circ J, 76(9), 2112-2118, 2012
  61. Phenotype variability in patients carrying KCNJ2 mutations., Circ Cardiovasc Genet, 5(3), 344-353, 2012
  62. Clinical and electrocardiographic characteristics of patients with short QT interval in a large hospital-based population., Heart Rhythm, 9(1), 66-74, 2012
  63. KCNE5 (KCNE1L) variants are novel modulators of Brugada syndrome and idiopathic ventricular fibrillation., Circ Arrhythm Electrophysiol, 4(3), 352-361, 2011
  64. Atrioventricular block-induced Torsades de Pointes with clinical and molecular backgrounds similar to congenital long QT syndrome., Circ J, 74(12), 2562-2571, 2010
  65. Heart rate-dependent variability of cardiac events in type 2 congenital long-QT syndrome., Europace, 12(11), 1623-1629, 2010
  66. Long QT syndrome with compound mutations is associated with a more severe phenotype: a Japanese multicenter study., Heart Rhythm, 7(10), 1411-1418, 2010
  67. High prevalence of early repolarization in short QT syndrome., Heart Rhythm, 7(5), 647-652, 2010
  68. KCNE2 modulation of Kv4.3 current and its potential role in fatal rhythm disorders., Heart Rhythm, 7(2), 199-205, 2010
  69. Dynamic change in ST-segment and spontaneous occurrence of ventricular fibrillation in Brugada syndrome with a novel nonsense mutation in the SCN5A gene during long-term follow-up., Circ J, 73(3), 584-588, 2009
  70. Hydroxyzine, a first generation H(1)-receptor antagonist, inhibits human ether-a-go-go-related gene (HERG) current and causes syncope in a patient with the HERG mutation., J Pharmacol Sci, 108(4), 462-471, 2008
  71. A novel KCNH2 mutation as a modifier for short QT interval., Int J Cardiol, 137(1), 83-85, 2009
  72. Mutation site dependent variability of cardiac events in Japanese LQT2 form of congenital long-QT syndrome., Circ J, 72(5), 694-699, 2008
  73. Age- and genotype-specific triggers for life-threatening arrhythmia in the genotyped long QT syndrome., J Cardiovasc Electrophysiol, 19(8), 794-799, 2008
  74. Disorders of cardiac repolarization: long QT and short QT syndromes., Circ J, 71(Supple A), A50-A53, 2007
  75. A paradoxical effect of lidocaine for the N406S mutation of SCN5A associated with Brugada syndrome., Int J Cardiol, 121(3), 239-248, 2007
  76. N- and C-terminal KCNE1 mutations cause distinct phenotypes of long QT syndrome., Heart Rhythm, 4(3), 332-340, 2007
  77. Arrhythmogenesis in the short-QT syndrome associated with combined HERG channel gating defects: a simulation study., Circ J, 70(4), 502-508, 2006
  78. Usefulness of fluorine-18-fluorodeoxyglucose positron emission tomography in a patient with Takayasu's arteritis associated with antiphospholipid syndrome., Int Heart J, 47(2), 311-317, 2006
  79. A novel missense mutation in the SCN5A gene associated with Brugada syndrome bidirectionally affecting blocking actions of antiarrhythmic drugs., J Cardiovasc Electrophysiol, 16(5), 486-493, 2005
  80. Clinical and electrophysiological characteristics of Brugada syndrome caused by a missense mutation in the S5-pore site of SCN5A., J Cardiovasc Electrophysiol, 16(4), 378-383, 2005
  81. Brugada syndrome with ventricular tachycardia and fibrillation related to hypokalemia., Circ J, 67(1), 93-95, 2003
  82. T-peak to T-end interval may be a better predictor of high-risk patients with hypertrophic cardiomyopathy associated with a cardiac troponin I mutation than QT dispersion., Clin Cardiol, 25(7), 335-339, 2002
  83. Perfusable tissue index obtained by positron emission tomography as a marker of myocardial viability in patients with ischemic ventricular dysfunction., Circ J, 66(4), 341-344, 2002
  84. Septal wall thinning and systolic dysfunction in patients with hypertrophic cardiomyopathy caused by a cardiac troponin I gene mutation., Am Heart J, 143(4), 690-695, 2002
  85. Cardiovascular imaging in-a-month. A 49-year-old man with lip swelling. Angioedema associated with angiotensin II receptor blockade, J Cardiol, 38(6), 355-356, 2001
  86. Increased QT dispersion does not reflect the increased regional variation of cardiac sympathetic nervous activity in hypertrophic cardiomyopathy., Am Heart J, 142(2), 358-362, 2001
  87. Arrhythmias in patients with Brugada-type electrocardiographic findings., Circ J, 65(6), 483-486, 2001
  88. Systolic dysfunction and blood pressure responses to supine exercise in patients with hypertrophic cardiomyopathy., Jpn Circ J, 65(4), 325-329, 2001
  89. A 65-year-old man with syncope, J Cardiol, 37(2), 121-124, 2001
  90. Microvascular ischemia in patients with myotonic dystrophy., Jpn Circ J, 64(9), 720-722, 2000
  91. Clinical Care Recommendations for Cardiologists Treating Adults with Myotonic Dystrophy, JAHA: Journal of the American Heart Association, 2020
  92. Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome, Circulation, 2020
  93. A computational analysis of the effect of sevoflurane in a human ventricular cell model of long QT syndrome: Importance of repolarisation reserve in the QT-prolonging effect of sevoflurane., European Journal of Pharmacology, 2020
  94. Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls., Genet Med, 2020
  95. Systematic Evaluation of KCNQ1 Variant Using ACMG/AMP Guidelines and Risk Stratification in Long QT Syndrome Type 1, Circ Genom Precis Med, 2020
  96. 2020 JCS/JHRS Guideline on Pharmacotherapy of Cardiac Arrhythmias On behalf of the Japanese Circulation Society and Japanese Heart Rhythm Society Joint Working Group, Circ J, 2021
  97. High incidence of major bleeding with off-label use of edoxaban, 2021
  98. Differences in pharmaceutical intervention triggers for the optimization of medication by patient age: A university hospital study, Biol Pharm Bull, 2021
  99. Sudden death after inappropriate shocks of implantable cardioverter defibrillator in a catecholaminergic polymorphic ventricular tachycardia case with a novel RyR2 mutation, Journal of Electrocardiology, 2021

Publications such as books

  1. Management of Cardiac Arrhythmias, 3rd ed., 20. Acquired long QT syndrome and torsades de pointes, Springer Nature, Scholarly Book, Joint work, Yan GX, Kowey PR, Antzelevitch C (Eds.) Itoh H, Shimizu W (Chap20)

Invited Lecture, Oral Presentation, Poster Presentation

  1. An incident caused by mismatched implant selection during surgery assessed with FRAM, Yusuke Watadani, Kiyoko Ukon, Satoru Izumitani, Sachiko Nakata, Akiko Kimura, Hideki Itoh, International Forum on Quality and Safety in Healthcare, 2024/04/11, Without Invitation, English, BMJ, London
  2. Impact of safety-II approach against the disconnection of drainage tubes, Kimura A, Izumitani S, Ukon K, Nakata S, Watadani Y, Itoh H, International Forum on Quality and Safety in Healthcare, 2024/04/11, Without Invitation, English, BMJ, London
  3. Phenotype variability in patients carrying KCNJ2 mutations, Kimura H, Zhou J, Itoh H., Mizusawa Y, Miyamoto A, Kawamura M, Makiyama T, Ito M, Matsuura H, Horie M, ESC Congress 2011 (Paris), 2011/08, Without Invitation, English
  4. Long QT syndrome with compound mutations is associated with a severer phenotype: a Japanese multicenter study, H. Itoh, W. Shimizu, K. Hayashi, K. Yamagata, T. Sakaguchi, T. Makiyama, Y. Miyamoto, M. Yamagishi, S. Kamakura, M. Horie, ESC congress 2010 (Stockholm), 2010/09, Without Invitation, English
  5. SCN5A and Lamin A/C Gene Mutations are Highly Prevalent in Patients with Familial Bradyarrhythmic Disorders, Makiyama Takeru, Akao Masaharu, Shizuta Satoshi, Doi Takahiro, Oono Seiko, Nishio Yukiko, Hattori Tetsuhisa, Tsuji Keiko, Itoh Hideki, Kimura Takesi, Yokode Masayuki, Kita Toru, Horie Minoru, The 73rd Annual Scientific Meeting of The Japanese Circulation Society, Without Invitation, English
  6. Severer Phenotypes of Long QT Syndrome are Associated with Compound Mutations : A Multicenter Study, Itoh Hideki, Shimizu Wataru, Yamagata Kenichiro, Sakaguchi Tomoko, Oono Seiko, Makiyama Takeru, Akao Masaharu, Noda Takashi, Miyamoto Yoshihiro, Kamakura Shiro, Horie Minoru, The 73rd Annual Scientific Meeting of The Japanese Circulation Society, Without Invitation, English
  7. Event ECG Recording is Useful Tool for Atrial Fibrillation (AF) Recurrence after Pulmonary Vein Isolation (PVI), Ito Makoto, Nakazawa Yuko, Yao Takenori, Ashihara Takashi, Joh Hikari, Itoh Hideki, Sugimoto Yoshihisa, Horie Minoru, The 73rd Annual Scientific Meeting of The Japanese Circulation Society (Symposium ), Without Invitation, English
  8. A Novel Genetic Marker for Potential Risk of QT Prolongation and Cardiac Sudden Death : KCNE1-D85N Polymorphism, Nishio Yukiko, Itoh Hideki, Makiyama Takeru, Sakaguchi Tomoko, Oono Seiko, Akao Masaharu, Matsuura Hiroshi, Kita Toru, Horie Minoru, The 73rd Annual Scientific Meeting of The Japanese Circulation Society (Symposium ), Without Invitation
  9. SCN5A and Lamin A/C Gone Mutations are Highly Prevalent In Patients with Familial Bradyarrhythmic Disorders, Takeru Maklyama, Masaharu Akao, Satoshi Shizuta, Takahiro Doi, Seiko Ohno, Yukko Nishio, Keiko Tsuji, Hideki Itoh, Toru Kita, Minoru Horie, 81st Annual Scientific Session of the American-Heart-Association, 2008/10, Without Invitation, English
  10. A KCNE1 polymorphism, D85N, is a disease-causing gene variant in congenital long QT syndrome, M. Horie, S. Ohno, Y. Nishio, H. Itoh, K. Tsuji, T. Sakaguchi, T. Makiyama, M. Akao, ESC congress 2008, Without Invitation, English
  11. Overlap Between LQT3 and Brugada Syndrome : Clinical Features in a Common Mutation and Underlying Biophysical Mechanisms, Makita Naomasa, Shimizu Wataru, Horie Minoru, Itoh Hideki, Kamakura Shiro, Tsutsui Hiroyuki, The 72nd Annual Scientific Meeting of the Japanese Circulation Society, 2008/03, Without Invitation
  12. Brugada Syndrome and Diverse Phenotypes of Cardiac Sodium Channelopathies, Makiyama Takeru, Akao Masaharu, Doi Takahiro, Oono Seiko, Nishio Yukiko, Oka Yuko, Tsuji Keiko, Itoh Hideki, Kita Toru, Horie Minoru, The 72nd Annual Scientific Meeting of the Japanese Circulation Society, 2008/03, Without Invitation
  13. A Common KCNE1 Polymorphism, D85N, is a Genetic Modifier of Long QT Syndrome, Nishio Yukiko, Yamamoto Satoshi, Makita Naomasa, Makiyama Takeru, Itoh Hideki, Sakaguchi Tomoko, Ohno Seiko, Akao Masaharu, Kita Toru, Horie Minoru, The 72nd Annual Scientific Meeting of the Japanese Circulation Society, 2008/03, Without Invitation, Japanese
  14. Additional Linear Ablation Lines do not Reduce AF Recurrence after Pulmonary Vein Isolation in the Paroxysmal and Persistent AF, Ito Makoto, Nakazawa Yuko, Yao Takenori, Joh Hikari, Itoh Hideki, Ashihara Takashi, Sugimoto Yoshihisa, Horie Minoru, The 72nd Annual Scientific Meeting of the Japanese Circulation Society, 2008/03, Without Invitation, English
  15. Cardiac sodium channel gene mutations are prevalent in Japanese patients with familial sick sinus syndrome, Makiyama Takeru, Akao Masaharu, Oka Yuko, Doi Takahiro, Oono Seiko, Nishio Yukiko, Tsuji Keiko, Itoh Hideki, Kita Toru, Horie Minoru, The 72nd Annual Scientific Meeting of the Japanese Circulation Society, 2008/03, Without Invitation, English
  16. Early and Late Recurrences of Atrial Fibrillation after Pulmonary Vein Isolation : A Study Using Event-ECG Monitors, Ashihara Takashi, Nakazawa Yuko, Yao Takenori, Hikari Joh, Itoh Hideki, Sugimoto Yoshihisa, Ito Makoto, Horie Minoru, The 72nd Annual Scientific Meeting of the Japanese Circulation Society, 2008/03, Without Invitation, English
  17. A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation, Makiyama Takeru, Akao Masaharu, Shizuta Satoshi, Doi Takahiro, Nishiyama Kei, Oka Yuko, Oono Seiko, Nishio Yukiko, Tsuji Keiko, Itoh Hideki, Kimura Takeshi, Kita Toru, Horie Minoru, The 72nd Annual Scientific Meeting of the Japanese Circulation Society, 2008/03, Without Invitation, English
  18. Plasma endotheline-1 level before extensive encircling pulmonary vein isolation as a predictor of atrial fibrillation recurrences after 6 months, Y. Nakazawa, T. Ashihara, T. Yao, T. Tanaka, H. Sakai, H. Jo, H. Itoh, T. Yagi, Y. Sugimoto, T. Tsutamoto, M. Ito, M. Horie, 10th International Workshop on Cardiac Arrhythmias, 2007/10, Without Invitation, English
  19. Prediction and prevention of T-WAVE oversensing in patients with implantable cardioverter defibrillators, T. Yao, H. Jo, Y. Nakazawa, T. Ashihara, H. Itoh, Y. Sugimoto, M. Ito, M. Horie, 10th International Workshop on Cardiac Arrhythmias, 2007/10, Without Invitation, English
  20. Age-related triggers for life-threatning arrhythmia in the genotyped long QT syndrome, Tomoko Sakaguchi, Wataru Shimizu, Hideki Ito, Takashi Noda, Yoshihiro Miyamoto, Iori Nagaoka, Takashi Ashihara, Makoto Ito, Keiko Tsuji, Seiko Ohno, Takeru Makiyama, Shiro Kamakura, Minoru Horie, 80th Annual Scientific Session of the American-Heart-Association, 2007/10, Without Invitation, English
  21. Overlap between LQT3 and Brugada syndrome: Clinical features in a common mutation and underlying biophysical mechanisms, Naomasa Makita, Elijah Behr, Wataru Shimizu, Minoru Horie, Lia Crotti, Hideki Itoh, Koji Miyamoto, Shiro Kamakura, Horoyuki Tsutsui, Peter J. Schwartz, Alfred L. George, Dan M. Roden, 80th Annual Scientific Session of the American-Heart-Association, 2007/10, Without Invitation, English
  22. Bradycardia before beta-blocker therapy as an arrhythmic risk in LQT2 form of congenital long-QT syndrome, I. Nagaoka, W. Shimizu, H. Itoh, T. Ashihara, M. Ito, S. Ohno, M. Akao, Y. Miyamoto, S. Kamakura, M. Horie, ESC congress, Without Invitation, English
  23. N- And C-terminal KCNE1 Mutations Cause Distinct Phenotypes of Long QT Syndrome, Ohno Seiko, Zankov Dimitar, Yoshida Hidetada, Tsuji Keiko, Makiyama Takeru, Itoh Hideki, Akao Masaharu, Kita Toru, Horie Minoru, 56th Annual Scientific Session of the American-College-of-Cardiology, 2007/03/06, Without Invitation, English
  24. Mutation Analysis for the Human Cardiac Ryanodine Receptor Gene (RyR2) in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT), Nagaoka Iori, Itoh Hideki, Sakaguchi Tomoko, Oka Yuko, Ashihara Takashi, Yao Takenori, Joh Hikari, Nakazawa Yuko, Ito Makoto, Sumitomo Naokata, Horie Minoru, 56th Annual Scientific Session of the American-College-of-Cardiology, 2007/03/06, Without Invitation, English
  25. Variable Genetic Backgrounds Between Congenital and Acquired Long-QT Syndromes, Itoh Hideki, Makiyama Takeru, Oono Seiko, Tsuji Keiko, Oka Yuko, Sakaguchi Tomoko, Nagaoka Iori, Nakazawa Yuko, Yao Takenori, Ashihara Takashi, Ito Makoto, Akao Masaharu, Horie Minoru, The 71st Annual Scientific Meeting of the Japanese Circulation Society, 2007/03, Without Invitation, English
  26. Clinical Characteristics for Japanese Patients with Genotyped Long-QT Syndrome, Oka Yuko, Makiyama Takeru, Itoh Hideki, Oono Seiko, Sakaguchi Tomoko, Nagaoka Iori, Ashihara Takashi, Ito Makoto, Akao Masaharu, Horie Minoru, The 71st Annual Scientific Meeting of the Japanese Circulation Society, 2007/03, Without Invitation, English
  27. Variable genetic backgrounds between congenital and acquired long QT syndromes, Hideki Itoh, Takeru Makiyama, Seiko Ohno, Yuko Oka, Tomoko Sakaguchi, Iori Nagaoka, Takashi Ashihara, Makoto Ito, Masaharu Akao, Minoru Horie, 56th Annual Scientific Session of the American-College-of-Cardiology, 2007/03/06, Without Invitation, English
  28. A novel KCNH2 mutation associated with the short QT interval of Brugada syndrome: Impaired deactivation for the I-Kr channel, Hideki Itoh, Tomoko Sakaguchi, Wei-Guang Ding, Keiko Tsuji, Takashi Ashihara, Yuko Nakazawa, Hikari Jo, Takenori Yao, Makoto Ito, Hiroshi Matsuura, Minoru Horie, 56th Annual Scientific Session of the American-College-of-Cardiology, 2007/03/06, Without Invitation, English
  29. Clinical Characteristics Associated with Mutation Sites in LQT2 Form of Congenital Long-QT Syndrome, Nagaoka Iori, Shimizu Wataru, Itoh Hideki, Yamamoto Satoshi, Sakaguchi Tomoko, Yoshida Hidetada, Oono Seiko, Akao Masaharu, Horie Minoru, The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society, 2006/03, Without Invitation, English
  30. Age-Related Triggers for Life-Threatening Arrhythmia in Genotyped Long-QT Syndrome, Sakaguchi Tomoko, Itoh Hideki, Yamamoto Satoshi, Nagaoka Iori, Yoshida Hidetada, Oono Seiko, Makiyama Takeru, Akao Masaharu, Horie Minoru, The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society, 2006/03, Without Invitation, English
  31. Lidocaine Prevents Brugada Syndrome with the N406S Mutation of SCN5A from Going into the Intermediate Inactivation, Itoh Hideki, Imoto Keiji, Ito Makoto, Horie Minoru, The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society, 2006/03, Without Invitation, English
  32. High Incidence of Cardiac Events for Long-QT Syndrome with Compound Mutations, Itoh Hideki, Sakaguchi Tomoko, Yamamoto Satoshi, Nagaoka Iori, Makiyama Takeru, Yoshida Hidetada, Ohno Seiko, Tsuji Keiko, Akao Masaharu, Horie Minoru, The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society, 2006/03/01, Without Invitation, English
  33. A KCNE1 Single Nucleotide Polymorphism, D85N, Serves as a Modifier in Forme-fruste Type of Long QT syndrome, Yamamoto Satoshi, Itoh Hideki, Sakaguchi Tomoko, Nagaoka Iori, Yoshida Hidetada, Oono Seiko, Makiyama Takeru, Akao Masaharu, Makita Naomasa, Shimizu Wataru, Horie Minoru, The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society, 2006/03/01, Without Invitation, English
  34. Lidocaine prevents Brugada syndrome with the N406S mutation of SCN5A from going into the intermediate inactivation, H Itoh, K Imoto, M Ito, M Horie, 78th Annual Scientific Session of the American-Heart-Association, 2005/10, Without Invitation, English
  35. A Novel Missense Mutation of SCN5A Gene Associated with Brugada Syndrome by Bidirectional Effects on Blocking Actions of Antiarrhythmic Drugs: Featured Research Session, Itoh Hideki, Imoto Keiji, Shimizu Masami, Mabuchi Hiroshi, 2004/03/01, Without Invitation, English
  36. SCN5A Mutations in the S5-S6 Region Cause Brugada Syndromeand Cardiac Conduction Disturbances, Itoh Hideki, Hirase Hiroaki, Araie Etsuro, Sakai Osamu, Shimizu Masami, 2003/03/01, Without Invitation
  37. SCN5A mutations in the S5-S6 region cause brugada syndrome and cardiac conduction disturbances, H Itoh, M Shimizu, H Mabuchi, 52nd Annual Scientific Session of the American-College-of-Cardiology, 2003/03, Without Invitation, English
  38. SCN5A gene mutations and clinical characteristics in patients with Brugada-type electrocardiogram, ITOH H, Shimizu Masami, Ino Hidekazu, Yamaguchi Masato, Hayashi Kenshi, Mabuchi Hiroshi, Without Invitation, Japanese
  39. SCN5A gene mutations and clinical characteristics in patients with Brugada syndrome, H Itoh, M Shimizu, H Ino, M Yamaguchi, K Hayashi, H Mabuchi, American Heart Association 2001 Scientific Sessions, 2001/10, Without Invitation, English
  40. Left ventricular functions in patients with coronary artery disease assessed by quantitative blood-pool SPECT and gated Technetium-99m Tetrofosmin SPECT: Comparison with assessment by contrast ventriculography, Itoh H, 2001, Without Invitation, English
  41. Arrhythmic events and ST-segment elevation in Brugeda syndrome, Hideki Itoh, Masami Shimizu, Hidekazu Ino, Masato Yamaguchi, Hiroshi Mabuchi., THE AMERICAN COLLEGE OF CARDIOLOGY 49TH ANNUAL SCIENTIFIC SESSION, 2000/02, Without Invitation, English, ANAHEIM, CALIFORNIA
  42. Clinical characteristics and effect of sex difference on clinical outcomes in octogenarians with acute coronary syndrome, K Oe, M Shimizu, H Ino, K Okeie, M Yamaguchi, K Hayashi, M Nagata, T Iwaki, H Ito, H Mabuchi, ESC congress 2001, 2001/09, Without Invitation, English
  43. A novel KvLQT1 mutation (F193L) characterized by mild phenotype in long QT syndrome, M Yamaguchi, M Shimizu, H Ino, K Hayashi, M Nagata, H Ito, T Iwaki, K Oe, T Konno, H Mabuchi, ESC congress 2001, 2001/09, Without Invitation, English
  44. Genotype-phenotypes relations of SCN5A-positive Brugada syndrome, Itoh Hideki, Makiyama Takeru, Yoshida Hidetada, Akao Masaharu, Makita Naomasa, Horie Minoru, 2006/03, Without Invitation
  45. Latent genetic backgrounds and molecular pathogenesis inacquired long QT syndrome with distinct arrhythmic triggers, Itoh H, Oka Y, Ding WG, Sakaguchi T, Kimura H, Mizusawa Y, Miyamoto A, Wu J, Ohno S, Makiyama T, Ito M, Matsuura H, Horie M, American Heart Association (AHA) 2010 Scientific Sessions (Chicago), 2010/11, Without Invitation, English
  46. Over-expression of heterozygous KCNJ2-M301K channels, identified in a patient with short QT syndrome, shortened action potential durations in neonatal rat ventricular myocytes, Hattori T, Makiyama T, Akao M, Ehara E, Ohno S, Iguchi M, Sasaki K, Itoh H, Horie M, Kimura T, ESC Congress 2011 (Paris), 2011/08, Without Invitation, English
  47. Long QT Syndromes are heterogeneous disease entities presenting not only QT prolongation but multiple phenotypes - Cases with compound heterozygous mutations, Horie M, Itoh H, Shimizu W, Hayashi K, Ohno S, Makiyama T, Yamagishi M, Kamakura S, APHRS2011 & 26th JHRS 28th JSE, 2011/09, Without Invitation
  48. Mutations of the cardiac ryanodine Recepter (RyR2) gene in catecholaminergic polymorphic ventricular tachycardia, Kawamura M, Nagaoka I, Kenichi, Nishio Y, Itoh H, Kimura H, Miyamoto A, Mizusawa Y, Jito Y, Ishida K, Ito M, Makiyama T, Ohno S, Sumitomo N, Oyama K, Horie M, APHRS2011 & 26th JHRS 28th JSE, 2011/09, Without Invitation
  49. Site-specific arrhythmogenesis in structurally normal heart of non-brugada patients with ventricular arrhythmias originating from ventricular outflow tract. Mini-Symposium, Ozawa T, Ito M, Itoh H, Nakazawa Y, Sugimoto Y, Yao T, Miyamoto A, Ashihara T, Horie M, APHRS2011 & 26th JHRS 28th JSE, 2011/09, Without Invitation
  50. KCNE5 variants are novel modulators of brugada syndrome and idiopathic ventricular fibrillation. Young Investigator Award Competition, Ohno S, Zankov DP, Ding WG, Itoh H, Makiyama T, Doi T, Shizuta S, Hattori T, Miyamoto A, Naiki N, Matsuura H, Horie M, APHRS2011 & 26th JHRS 28th JSE, 2011/09, Without Invitation
  51. Clinical differences between KCNH2 and SCN5A mutation carriers with Brugada syndrome and Brugada-like ECG patients in Japan, Ohno S, Miyamoto A, T Makiyama, Itoh H, Horie M, AHA Scientific Sessions 2011 Orlando, Florida, U.S.A., 2011/11, Without Invitation, English
  52. Clinical and genetic characterization of Japanese patients with arrhythmogenic right ventricular cardiomyopathy, Ohno S, Nishio Y, Nagaoka I, Miyamoto A, Kimura H, Itoh H, Makiyama T, Horie M, AHA Scientific Sessions 2011 Orlando, Florida, U.S.A., 2011/11, Without Invitation, English
  53. KCNJ2-R218Q/W is a hot spot with strong phenotype in Andersen-tawil syndrome, Kimura H, Ohno S, Itoh H, Kawamura M, Naiki N, Wang Q, Makiyama T, Ito M, Horie M, The Heart Rhythm Society's 33rd Annual Scientific Sessions, 2012/05, Without Invitation, English
  54. Novel CACNA1C mutations identified in Japanese patients caused both Brugada syndrome and Idiopathic Ventricular Fibrillation without QT shortening, FukuyamaM, Ohno S, Wang Q, Kimura H, Miyamoto A, Makiyama T, Itoh H, Itoh M, Horie M, ESC CONGRESS 2012 (Munich, Germany), 2012/08, Without Invitation, English
  55. Age dependent clinical and genetic characteristics in Japanese patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia, Ohno S, Nishio Y, Nagaoka I, Fukuyama M, Kimura H, Itoh H, Makiyama T, Shimizu A, Horie M, The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (Taipe), 2012/10, Without Invitation, English
  56. Functional analysis of novel KCNH2, Wang Q, Ohno S, Miyamoto A, Ding WG, Wu J, Kimura H, Itoh H, Makiyama T, Matsuura H, Horie M, The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (Taipe), 2012/10, Without Invitation, English
  57. Mutations identified in Brugada syndrome patients with or without ventricular fibrillation, Kawamura M, Ohno S, Naiki N, Nagaoka I, Dohchi K, Kimura H, Hasegawa K, Wang Q, Itoh H, Makiyama T, Horie M, The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (Taipe), 2012/10, Without Invitation, English
  58. Genetic background of catecholaminergic polymorphic ventricular tachycardia in Japan CHA2DS2-VASc score and left atrial size are important to predict recurrence of atrial fibrillation after pulmonary vein isolation: usefulness of event ECG home monitoring, Ito M, Ozawa T, Nakazawa Y, Sugimoto Y, Itoh H, Ashihara T, Dochi K, Kato K, Horie M, The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (Taipe), 2012/10, Without Invitation, English
  59. A Rare KCNE1 Polymorphism, D85N, is a Genetic Modifier in Congenital Long QT Syndrome, Hasegawa K, Ohno S, Itoh H, Makiyama T, Horie M., The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (Taipe), 2012/10, Without Invitation, English
  60. Genotype-Phenotype Relationships in Patients with Familial Bradyarrhythmias; SCN5A Versus LMNA Gene Mutations, Makiyama T, Sasaki K, Kamakura T, Shizuta S, Cheng J, Wuriyanghai Y, Ohno S, Itoh H, Horie M, Kimura T, The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (Taipe), 2012/10, Without Invitation, English
  61. CACNA1C Mutations in Japanese Patients with Brugada Syndrome or Idiopathic Ventricular Fibrillation, Fukuyama M, Ohno S, Wang Q, Kimura H, Itoh H, Makiyama T, Ito M, Horie M, The 5th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with The 8th Asia-Pacific Atrial Fibrillation Symposium (Taipe), 2012/10, Without Invitation, English
  62. Novel KCNQ1 missense mutation associated with juvenile-onset atrial fibrillation, Hasegawa K, Ohno S, Itoh H, Hattori T, Makiyama T, Toyoda F, Ding WG, Chinushi M, Matsuura H, Horie M, AHA Scientific Sessions 2012, 2012/11, Without Invitation, English
  63. Asymmetry of parental origin in Long QT syndrome, Itoh H, Berthet M, Fressart V, Denjoy I , Maugenre S, Klug D, Mizusawa Y, Makiyama T, Hofman N, Husemann A, Shimizu W, Wilde AA , Schulze-Bahr E, Horie M, du Montcel ST, Guicheney P, European Human Genetics Conference, 2013/06, Without Invitation, English
  64. Exon-3 deletion of RyR2 encoding cardiac ryanodine receptor related to left ventricular non-compaction (LVNC) with ventricular arrhythmia and bradycardia, Ohno S, Omura M, Kawamura M, Kimura H, Itoh H, Makiyama T, Ushinohama H, Makita N, Horie M, EHRA EUROPACE 2013, 2013/06, Without Invitation, English
  65. Underlying Mechanisms in Forme Fruste Long QT Syndrome Manifested by Acquired Factors, Itoh H, The 2nd HD Physiology International Symposium (Tokyo), 2013/06, Without Invitation
  66. Novel CACNA1C mutations in Long QT syndrome patients- The subtype of Long QT syndrome type 8, Fukuyama M, Wang Q, Kato K, Ohno S, Kimura H, Makiyama T, Itoh H, Ito M, Matsuura H, Horie M, Denis Escande Symposium 2013, 2013/08, Without Invitation, English
  67. Copy number variation in KCNQ1 gene were frequently identified in the pediatric patients of long QT syndrome and caused exercise related QT prolongation, Ohno S, Fukuyama M, Itoh H, Makiyama T, Horie M, ESC CONGRESS 2013 (Amsterdam, The Netherlands), 2013/08, Without Invitation, English
  68. Altered splicing of cardiac sodium channel might be responsible for cardiac conduction defects in myotonic dystrophy, Kokunai Y, Kino Y, Li M, Itoh H, Nakamori M, Kimura T, Matsumura T, Fujimura H, Nukina N, Sakoda S, Horie M, Imoto K, Ishiura S, Swanson MS, Charlet-Berguerand N, Takahashi MP, The 9th International Myotonic Dystrophy Consortium (Basque, Spain), 2013/10, Without Invitation, English
  69. Phenotypic characterization of three patients with lethal arrhythmia related to KCNH2-R148W missense mutation, Ohno S, Wang Q, Hasegwas K, Itoh H, Makiyama T, Horie M, 6th APHRS & CardioRhythm 2013 (Hong Kong, China), 2013/10, Without Invitation, English
  70. The high prevalence of early repolarization in genotyped long-standing persistent atrial fibrillation, Hasegawa K, Watanabe H, Ohno S, Itoh H, Makiyama T, Ashihara T, Hayashi H, Horie M, The 10th Asia-Pacific Heart Rhythm Society Scientific Session (APHRS) in conjunction with the Annual Meeting of the Japanese Heart Rhythm Society (JHRS), 2017/09, Without Invitation, English
  71. The high prevalence of early repolarization in genotyped long QT syndrome, Hasegawa K, Watanabe H, Ohno S, Itoh H, Makiyama T, Ashihara T, Hayashi H, Horie M, American Heart Association (AHA) 85th Scientific Sessions, 2013/11, Without Invitation, English
  72. Mosaic KCNJ2 Mutation in Andersen-Tawil syndrome:Targeted Deep Sequencing is Useful for the Detection of Mosaicism, Hasegawa K, Ohno S, Kimura H, Itoh H, Makiyama T, Yoshida Y, Horie M, Heart Rhythm2014 (San Francisco,Ca,U.S.A), 2014/05, Without Invitation, English
  73. Genetics in acquired long QT syndrome, Pedrazzini M, Itoh H, Crotti L, Aiba T, Denjoy I, Fressart V, Hayashi K, Nakajima T, Ohno S, Makiyama T, Wu J, Hasegawa K, Mastantuono E, Dagradi F, Yamagishi M, Berthet M, Shimizu W, Guicheney P, Schwartz PJ, Horie M, ESHG 2014 (Milano, Italy), 2014/05, Without Invitation, English
  74. Identification of latent mutations in primary inherited arrhythmia syndromes using benchtop next generation sequencer, Ohno S, Fukuyama M, Itoh H, Makiyama T, Horie M, ESC CONGRESS 2014 (Barcelona, Spain), 2014/08, Without Invitation, English
  75. High frequency of ANK2 mutations in patients with non-genotyped primary inherited arrhythmia syndromes, Ohno S, Fukuyama M, Itoh H, Makiyama T, Horie M, ESC CONGRESS 2014 (Barcelona, Spain), 2014/08, Without Invitation, English
  76. Identification of novel SCN10A variants in Brugada syndrome patients, Fukuyama M, Ohno S, Makiyama T, Hasegawa K, Itoh H, Horie M, ESC CONGRESS 2014 (Barcelona, Spain), 2014/08, Without Invitation, English
  77. Acquired long QT syndrome, Itoh H, 7th APHRS 2014 (New Delhi, India), 2014/10, With Invitation, English
  78. Young long QT syndrome patients with KCNH2 mutations have late onset but severe symptoms, Ozawa J, Ohno S, Itoh H, Makiyama T, Horie M, AHA Scientific Sessions 2014 (2014.11.15-19. Chicago, IL, U.S.A.), 2014/11, Without Invitation, English
  79. The Prognosis of Andersen-Tawil syndrome is not so benign as ever thought, Kimura H, Itoh H, Ohno S, Fukuyama M, Kato K, Ichikawa M, Fujii Y, Makiyama T, Horie M, AHA Scientific Sessions 2014 (2014.11.15-19. Chicago, IL, U.S.A.), 2014/11, Without Invitation, English
  80. Arrhythmogenic ventricular cardiomyopathy with peculiar ventricular aneurysm and TMEM43 mutations, Ichikawa M, Ohno S, Fujii Y, Ozawa J, Sonoda K, Fukuyama M, Kato K, Itoh H,Horie M, (2015.6.21-24. Milan, Italy), 2015/06, Without Invitation, English
  81. AKAP9 mutations identified in young patientswith idiopathic ventricular fibrillation or polymorphic ventricular tachycardia, Sonoda K, Ohno S, Ichikawa M, Fujii Y, Wang Q, Kato K, Fukuyama M, Ito H, Hayashi H, Horie M, ESC CONGRESS 2015 (2015.8.29-9.2, London, England), 2015/08, Without Invitation, English
  82. A novel CACNA1C mutation identified in a patient with atypical Timothy syndrome exerts both loss- and gain-of-function effects on Cav1.2, Ozawa J, Ohno S, Toyoda F, Itoh H, Fukuyama M, Harita T, Makiyama T, Hiroshi Suzuki, Akihiko Saitoh, Matsuura H, Horie M, ESC CONGRESS 2016 (2016.8.26-9.1. Rome, Italy), 2016/08, Without Invitation, English
  83. Triple mutations in three major genes for long QT syndrome are very rare but produce severe phenotypes, Ohno S, Wu J, Sonoda K, Itoh H, Makiyama T, Horie M, ESC CONGRESS 2016 (2016.8.26-9.1. Rome, Italy), 2016/08, Without Invitation, English
  84. Copy Number Variations in SCN5A associated with Brugada Syndrome, Sonoda K, Ohno S, Ozawa J, Hayano M, Ichikawa M, Ito H, Makiyama T, Horie M, ESC CONGRESS 2016 (2016.8.26-9.1. Rome, Italy), 2016/08, Without Invitation, English
  85. Triple mutations in three major genes for long QT syndrome are very rare and cause complicated phenotypes with ventricular arrhythmia, Ohno S, Wu J, Mizusawa Y, Sonoda K, Itoh H, Makiyama T, Horie M, ESC CONGRESS 2016 (2016.8.26-9.1. Rome, Italy), 2016/08, Without Invitation, English
  86. Copy number variations in SCN5A associated with Brugada syndrome, Sonoda K, Ohno S, Ozawa J, Hayano M, Ito H, Makiyama T, Horie M, ESC CONGRESS 2016 (2016.8.26-9.1. Rome, Italy), 2016/08, Without Invitation, English
  87. Specific phenotypes caused by RYR2 mutations relate with bradycardia but not with mutation locations in RYR2, Ohno S, Ozawa J, Fujii Y, Itoh H, Horie M, ESC CONGRESS 2016 (2016.8.26-9.1. Rome, Italy), 2016/08, Without Invitation, English
  88. RYR2 mutations underlying in patients with short-coupled variant of torsade de pointes, Fujii Y, Itoh H, Ohno S, Blancard M, Aoki H, Nakagawa Y, Yamamoto S, Matsui Y, Ichikawa M, Sonoda K, Ozawa T, Ohkubo K, Watanabe I, Guicheney P, Horie M, ESC CONGRESS 2016 (2016.8.26-9.1. Rome, Italy), 2016/08, Without Invitation, English
  89. KCNH2 mutation in patients with long QT syndrome type 2, Fukumoto D, Ohno S, Wada Y, Fujii Y, Ichikawa M, Ito H, Ding WG, Matsuura H, Horie M, 9th APHRS Scientific Session (2016.10.12-15. Korea), 2016/08, Without Invitation, English
  90. Various ANK2 mutations in patients with inherited primary arrhythmia syndromes, Ichikawa M, Aiba T, Ohno S, Shigemizu D, Ozawa J, Sonoda K, Fukuyama M, Itoh H, Miyamoto Y, Tsunoda T, Makiyama T, Tanaka T, Shimizu W, Horie M, 9th APHRS Scientific Session (2016.10.12-15. Korea), 2016/08, Without Invitation, English
  91. Novel N-Terminal KCNH2 Mutations Identified in Symptomatic Long QT Syndrome Patients, Fukumoto D, Ohno S, Wada Y, Fujii Y, Ichikawa M, Takayama K, Fukuyama M, Itoh H, Ding WG, Matsuura H, Horie M, APHRS2017 (2017.9.14-17. Yokohama), 2017/09, Without Invitation
  92. Next-Generation Sequencing Is One of the Promising Ways for Identifying Copy Number Variations in Patients with Inherited Primary Arrhythmia Syndromes, Ichikawa M, Ohno S, Fukumoto D, Takayama K, Wada Y, Fukuyama M, Makiyama T, Itoh H, Horie M, APHRS2017 (2017.9.14-17. Yokohama), 2017/09, Without Invitation
  93. Long QT Syndrome Type8. Novel CACNA1C Mutations Showing Variant Phenotypes, Fukuyama M, Wang Q, Kato K, Ohno S, Kimura H, Makiyama T, Itoh H, Ito M, Horie M, 2014/03, Without Invitation
  94. Nonsense-Mediated mRNA Decay due to a CACNA1C Splicing Mutation in a Patient with Brugada Syndrome, Fukuyama M, Ohno S, Wang Q, Shirayama T, Itoh H, Horie M, 2014/03, Without Invitation
  95. Cardiac Channelopathies Associated with Infantile Fatal Ventricular Arrhythmias, Kato K, Makiyama T, Wu J, Kimura H, Naiki N, Ohno S, Itoh H, Nakanishi T, Matsuura H, Horie M, 2014/03, Without Invitation
  96. The High Prevalence of Early Repolarization in Genotyped Long QT Syndrome, Hasegawa K, Watanabe H, Ohno S, Itoh H, Makiyama T, Ashihara T, Hayashi H, Horie M, 2014/03, Without Invitation
  97. Nonsense-Mediated mRNA Decay due to a CACNA1C Splicing Mutation in a Patient with Brugada Syndrome, Fukuyama M, Ohno S, Wang Q, ShirayamaT, Itoh H, Horie M, 2015/07, Without Invitation
  98. Usefulness of Benchtop Next Generation Sequencer in Research of Inherited Primary Arrhythmia Syndromes, Ohno S, Fukuyama M, Itoh H, Makiyama T, Horie M, 2015/04, Without Invitation
  99. The management of long QT syndrome. data in Japan and Europe, Itoh H, Horie M, 2016/07, Without Invitation
  100. RYR2 mutations underlying in patients with short-coupled variant of torsade de pointes, Fujii Y, Itoh H, Ohno S, Blancard M, Aoki H, Nakagawa Y, Yamamoto S, Matsui Y, Ichikawa M, sonoda K, Ozawa T, Ohkubo K, Watanabe I, Guicheney P, Horie M, 2016/03, Without Invitation
  101. AKAP9 mutations identified in young patients with idiopathic ventricular fibrillation or polymorphic ventricular tachycardia, Sonoda K, Ohno S, Wada Y, Ichikawa M, Fujii Y, Ozawa J, Itoh H, Ashihara T, Hayashi H, Horie M, 2016/03, Without Invitation
  102. A Novel Transport Refractory Mutation in KCNH2 Identified in Symptomatic Long QT Syndrome Patients, 2017/03, Without Invitation
  103. Copy Number Variations of SCN5A in Brugada Syndrome, 2017/03, Without Invitation
  104. Usefulness of Genetic Screening for Long QT syndrome in the School-Based Electrocardiographic Screening Programs, Fukuyama M, Ohno S, Ozawa J, Takayama K, Kato K, Itoh H, Aoki H, Makiyama T, Horie M, 2019/03, Without Invitation
  105. Identification of copy number variations by next generation sequencer in patients with inherited primary arrhythmia syndromes, Ichikawa M, Ohno S, Fukumoto D, Takayama K, Wada Y, Fukuyama M, Makiyama T, Itoh H, Horie M, ESC Congress 2017 (2017. 8. 26-30. Spain), 2017/08, Without Invitation
  106. Genetic analysis of candidate gene mutations in patients with short QT syndrome, Hattori T , Makiyama , Ohno S, Sasaki K, Kamakura T, Hayashi H, Itoh H, Horie M, Kimura T, 2012/03, Without Invitation
  107. Clinical characterisation of the patient with a common splicing mutation, KCNQ1-A344A, Dochi K, Ohno S, Itoh H, Itoh M, Horie M, 2012/03, Without Invitation
  108. Genetic Background for Arrhythmogenic Right Ventricular Cardiomyopathy/ Dysplasia(ARVC/D)in Japan, Horie M, Ohno S, Nagaoka I, Fukuyama M, Kimura H, Itoh H, 2012/07, Without Invitation

External Funds

Acceptance Results of Competitive Funds

  1. Practical Research Project for Rare / Intractable Diseases, 2024/04/01, 2025/03/31
  2. 2023
  3. 2022, 2022
  4. 2021, 2022
  5. 2007
  6. 2020, 2022

Social Activities

History as Committee Members

  1. 2017