TOMOHIRO SUGIMOTO

Last Updated :2026/06/02

Affiliations, Positions
Hiroshima University Hospital, Assistant Professor
E-mail
tsugimotohiroshima-u.ac.jp

Basic Information

Major Professional Backgrounds

  • 2010/04/01, 2012/03/31, Hiroshima Prefectural Hospital, Clinical Resident
  • 2012/04/01, 2014/03/31, Shobara Red Cross Hospital, Doctor
  • 2014/04/01, 2016/03/31, Onomichi municipal Hospital Setoda Clinic, Doctor
  • 2016/04/01, 2018/03/31, Jinsekikougen Town Hospital, Doctor
  • 2018/04/01, 2019/03/31, Hiroshima Prefecture, Doctor
  • 2019/04/01, Hiroshima University Hospital, Department of Clinical Immunology and Rheumatology, Assistant Professor

Educational Backgrounds

  • Jichi Medical School, Japan, 2004/04, 2010/03

Academic Degrees

  • Hiroshima University

In Charge of Primary Major Programs

  • Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Collagenous pathology / Allergology

Research Keywords

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Collagenous pathology / Allergology

Affiliated Academic Societies

  • The Japanese Society of Clinical Immunology
  • Japan College of Rheumatology
  • The Japanese Society of Internal Medicine
  • The Japanese Association for Infectious Diseases
  • Japanese Society for Sjogren's Syndrome

Educational Activity

Course in Charge

  1. 2026, Undergraduate Education, Year, Clinical diagnosis and treatment II
  2. 2026, Undergraduate Education, Intensive, Practice for medical research

Award of Education

  1. 2023/03/24

Research Activities

Academic Papers

  1. Serum calprotectin elevation and interferon-α-induced neutrophil priming in macrophage activation syndrome associated with systemic lupus erythematosus: clinical and experimental insights., Mod Rheumatol., 20260224
  2. Frequent detection of antinuclear antibodies and low-titre rheumatoid factor in female patients with undifferentiated peripheral spondyloarthritis in Japan: A prospective observational study, MODERN RHEUMATOLOGY, 35(4), 753-761, 202507
    Link to Paper Search Results by DOI
  3. Hsa-miR-21-5p is induced by interleukin-6 and affects multiple pathogenic factors associated with fibroblast-like synoviocytes in rheumatoid arthritis, SCIENTIFIC REPORTS, 15(1), 20250603
    Link to Paper Search Results by DOI
  4. Effectiveness and safety of rituximab in severely relapsed antineutrophil cytoplasmic antibody-associated vasculitis: a retrospective analysis of a Japanese multicentre cohort from the J-CANVAS, CLINICAL RHEUMATOLOGY, 43(10), 3195-3204, 202410
    Link to Paper Search Results by DOI
  5. Progressive multifocal leukoencephalopathy associated with systemic lupus erythematosus: longitudinal observation of lymphocytes, JC virus in cerebrospinal fluid, and brain magnetic resonance imaging, JOURNAL OF NEUROVIROLOGY, 30(2), 197-201, 202404
    Link to Paper Search Results by DOI
  6. The Lipopolysaccharide Mutant Re-LPS Is a Useful Tool for Detecting LPS Contamination in Rheumatoid Synovial Cell Cultures, PATHOBIOLOGY, 89(2), 92-100, 20220322
    Link to Paper Search Results by DOI
  7. Disseminated Mycobacterium abscessus infection with osteoarticular manifestations as an important differential diagnosis of inflammatory arthritis: A case report and literature review, MODERN RHEUMATOLOGY CASE REPORTS, 8(1), 49-54, 20231229
    Link to Paper Search Results by DOI
  8. Seasonal Influence on Development of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Retrospective Cohort Study Conducted at Multiple Institutions in Japan ( J- CANVAS), JOURNAL OF RHEUMATOLOGY, 50(9), 1152-1158, 20230901
    Link to Paper Search Results by DOI
  9. Tumor Necrosis Factor and Interleukin-1 beta Upregulate NRP2 Expression and Promote SARS-CoV-2 Proliferation, VIRUSES-BASEL, 15(7), 202307
    Link to Paper Search Results by DOI
  10. Safe Introduction of Hydroxychloroquine Focusing on Early Intolerance Due to Adverse Drug Reactions in Patients with Systemic Lupus Erythematosus, INTERNAL MEDICINE, 62(14), 2051-2057, 2023
    Link to Paper Search Results by DOI
  11. Fluorodeoxyglucose-positron emission tomography/computed tomography-positive ear lesions responsive to immunosuppressive therapy in a patient with otitis media with antineutrophil cytoplasmic antibody-associated vasculitis, MODERN RHEUMATOLOGY CASE REPORTS, 7(1), 134-137, 20230103
    Link to Paper Search Results by DOI
  12. Appearance of anti-MDA5 antibody-positive dermatomyositis after COVID-19 vaccination, MODERN RHEUMATOLOGY CASE REPORTS, 7(1), 108-112, 20230103
    Link to Paper Search Results by DOI
  13. Association between increased serum IL-23 levels and ACPA positivity in patients with rheumatoid arthritis, Clin Exp Rheumatol ., 202305
  14. Seasonal influence on development of anti-neutrophil cytoplasmic antibody-associated vasculitis: a retrospective cohort study conducted at multiple institutions in Japan (J-CANVAS), J Rheumatol, 2023
  15. Ameliorated nailfold capillary morphology of patients with pulmonary arterial hypertension in systemic sclerosis, treated with riociguat, Rheumatol Adv Pract, 20230119
  16. Safe Introduction of Hydroxychloroquine Focusing on Early Intolerance Due to Adverse Drug Reactions in Patients with Systemic Lupus Erythematosus, Intern Med, 20221116
  17. Appearance of anti-MDA5 antibody-positive dermatomyositis after COVID-19 vaccination, Mod Rheumatol Case Rep, 7(1), 108-112, 20230103
    Link to Paper Search Results by DOI
  18. Portal Vein Thrombosis as a Cause of Undetermined Thrombocytopenia with Liver Dysfunction in a Patient with Eosinophilic Granulomatosis with Polyangiitis, INTERNAL MEDICINE, 62(1), 123-127, 20230101
    Link to Paper Search Results by DOI
  19. Expression of factor XIII originating from synovial fibroblasts and macrophages induced by interleukin-6 signaling, INFLAMMATION AND REGENERATION, 43(1), 20230106
    Link to Paper Search Results by DOI
  20. Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography-Positive Ear Lesions Responsive to Immunosuppressive Therapy in a Patient with Otitis Media with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis, Mod Rheumatol Case Rep., 20230103
  21. Cryoglobulinemic Vasculitis Associated with Monoclonal Gammopathy of Undetermined Significance Developed after Sustained Virologic Response of Hepatitis C: A Case Report, Intern Med, 20221116
  22. C-reactive protein and ground-glass opacity as predictors for intractable interstitial lung disease in patients with systemic sclerosis under cyclophosphamide treatment regardless of concomitant glucocorticoids, MODERN RHEUMATOLOGY, 32(1), 141-148, 20220105
    Link to Paper Search Results by DOI
  23. Importance of anti-centromere antibodies in the diagnosis of Sjogren's syndrome, JOURNAL OF ORAL SCIENCE, 64(4), 324-326, 20221001
    Link to Paper Search Results by DOI
  24. Bilateral facial nerve palsy responded to immunosuppressive therapy in a patient with eosinophilic granulomatosis with polyangiitis, Rheumatol Adv Pract ., 20220829
  25. The Efficacy of Amenamevir for the Treatment of Disseminated Herpes Zoster Complicated with Probable Varicella-zoster Pneumonia in an Immunocompromised Patient, INTERNAL MEDICINE, 61(11), 1785-1788, 20220601
    Link to Paper Search Results by DOI
  26. ★, Nailfold capillaries and myositis-specific antibodies in anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis, RHEUMATOLOGY, 61(5), 2006-2015, 20220505
    Link to Paper Search Results by DOI
  27. The Lipopolysaccharide Mutant Re-LPS Is a Useful Tool for Detecting LPS Contamination in Rheumatoid Synovial Cell Cultures, Pathobiology, 89(2), 92-100, 2022
  28. Comment on: Combination of immunosuppressive therapy and nintedanib improves capillaroscopic changes in systemic sclerosis-interstitial lung disease: a case report, Rheumatol Adv Pract., 6(1), 20220531
  29. Exacerbation of systemic lupus erythematosus after receiving mRNA-1273-based coronavirus disease 2019 vaccine, J Dermatol., 49(6), e199-e200, 2022
  30. Comment on: Nailfold capillaries and myositis-specific antibodies in anti-melanoma differentiation-associated gene 5 antibody-positive DM. Reply, Rheumatology (Oxford), 61(5), e122-e124, 2022
  31. Lower CH50 as a predictor for intractable or recurrent lupus enteritis: A retrospective observational study, MODERN RHEUMATOLOGY, 31(3), 643-648, 20210504
    Link to Paper Search Results by DOI
  32. Tapering and discontinuation of oral glucocorticoids without deterioration of disease status in patients with rheumatoid arthritis under a stable treatment, MODERN RHEUMATOLOGY, 31(4), 803-808, 20210704
    Link to Paper Search Results by DOI
  33. The clinical characteristics and predictors of severe digital ischemia in patients with anti-aminoacyl transfer RNA synthetase antibodies, JOURNAL OF DERMATOLOGY, 48(7), 1044-1051, 202107
    Link to Paper Search Results by DOI
  34. Immunoglobulin D-kappa multiple myeloma in a patient with rheumatoid arthritis: a case report and review of the literature, MODERN RHEUMATOLOGY CASE REPORTS, 5(1), 22-28, 20210102
    Link to Paper Search Results by DOI
  35. Rapid changes of nailfold capillary abnormalities during treatment for a patient with dermatomyositis complicated by lung cancer: a case report, MODERN RHEUMATOLOGY CASE REPORTS, 5(1), 95-100, 20210102
    Link to Paper Search Results by DOI
  36. Asymptomatic coronary aneurysms in a patient with eosinophilic granulomatosis with polyangiitis who developed a digital gangrene, MODERN RHEUMATOLOGY CASE REPORTS, 5(1), 130-136, 20210102
    Link to Paper Search Results by DOI
  37. A Rare Case of IgG4-Related Disease Presenting as a Unilateral Severe Dacryoadenitis Complicated by Hypophysitis and Hypertrophic Pachymeningitis., J Clin Rheumatol, 27(8S), S571-S573, 2021
  38. Methotrexate-associated reversible liver atrophy in a patient with rheumatoid arthritis, Rheumatol Adv Pract, 2020
  39. Successful hydroxychloroquine treatment in a patient with systemic lupus erythematosus-associated nailfold capillary abnormalities., Rheumatol Adv Pract., 5(4), 2, 2020
  40. Multiple External Root Resorption of Teeth as a New Manifestation of Systemic Sclerosis-A Cross-Sectional Study in Japan, JOURNAL OF CLINICAL MEDICINE, 8(10), 201910
    Link to Paper Search Results by DOI

Publications such as books

  1. RHEUMATOLOGY, Nailfold capillary abnormalities in anti-MDA5 antibody-positive dermatomyositis, dermatomyositis, MDA5, nailfold capillary, nailfold video-capillaroscopy(NVC), KAGAKU-HYORONSHA Co., 2023, 2023, Scholarly Book, Single work, 日本語, Tomohiro Sugimoto, 336-343

Invited Lecture, Oral Presentation, Poster Presentation

  1. Clinical Diagnosis and Nailfold Capillaroscopy Abnormalities in Anti-Centromere Antibody-Positive Patients, Tomohiro Sugimoto, Naoya Oka, Hiroki Kobayashi, Takuji Omoto, Yohei Hosokawa, Genki Kidoguchi, Michinori Ishitoku, Yusuke Yoshida, Sho Mokuda, Shintaro Hirata, The 70th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology, 2026/04/24, Without Invitation, English, Japan College of Rheumatology, Fukuoka, Japan
  2. Arginase as potential indicators for improvement in nailfold capillary abnormalities in patients with systemic sclerosis treated with cyclophosphamide, Tomohiro Sugimoto, Michinori Ishitoku, Yusuke Yoshida, Sho Mokuda, Shintaro Hirata, 27th Asia-Pacific League of Associations for Rheumatology Congress, 2025/09/06, Without Invitation, English, APLAR, Fukuoka, Japan
  3. Unremarkable nailfold capillary abnormalities at baseline predict a poor prognosis in patients with anti-MDA5 antibody-positive dermatomyositis, Tomohiro Sugimoto, Michinori Ishitoku, Yusuke Yoshida, Sho Mokuda, Shintaro Hirata, The 69th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology, 2025/04/06, Without Invitation, English, Japan College of Rheumatology
  4. Impact of Rituximab vs. Cyclophosphamide on Nailfold Capillary Abnormalities in Patients with Systemic Sclerosis, Tomohiro Sugimoto, Hirofumi Watanabe, Yusuke Yoshida, Sho Mokuda, Shintaro Hirata, The 68th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology, 2024/04/20, Without Invitation, English, Japan College of Rheumatology
  5. Characteristics of nailfold capillary abnormalities in anti RNA polymerase III antibody positive systemic sclerosis, Tomohiro Sugimoto, Yusuke Yoshida, Sho Mokuda , Shintaro Hirata, The 67th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology, 2023/04/26, Without Invitation, English, Japan College of Rheumatology, Fukuoka
  6. Insufficient efficacy of immunosuppressants on skin sclerosis in patients with systemic sclerosis without interstitial lung disease, Tomohiro Sugimoto, Michinori Ishitoku, Hiroki Kohno, Yusuke Yoshida, Shintaro Hirata, The 66th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology, 2022/04/25, Without Invitation, English
  7. Insufficient efficacy of immunosuppressants on skin sclerosis in patients with systemic sclerosis without interstitial lung disease., Sugimoto T., Yoshida Y. Hirata S., 23rd Asia Pacific League of Associations for Rheumatology, 2021/08/28, Without Invitation, English
  8. Usefulness of nailfold video-capillaroscopy for diagnosing patients positive for anti-centromere antibody, Sugimoto T., Kobayashi H. Suma H. Hosokawa Y. Ishitoku M. Watanabe H. Tokunaga T. Ohnari S. Yoshida Y. Mokuda S. Hirata S. Sugiyaa E., The 65th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology, 2021/04/26, Without Invitation, English
  9. Nailfold Capillary Changes in Patients with Anti-Melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis., Sugimoto T., Yoshida Y., Mokuda S., Hirata S., Sugiyama E., 22rd Asia Pacific League of Associations for Rheumatology, 2020/10/24, Without Invitation, English
  10. Immunosuppressive treatment promptly improves abnormalities in nailfold capillaries in patients with dermatomyositis, Tomohiro Sugimoto, Takuji Omoto, Hiroki Kohno, Hirofumi Watanabe, Kazutoshi Yukawa, Tadahiro Tokunaga, Tatsuomi Kuranobu, Katsuhiro Oi, Yusuke Yoshida, Sho Mokuda, Keisuke Oda, Shintaro Hirata, Takaki Nojima, Eiji Sugiyama, 2020/08/17, Without Invitation, English

Awards

  1. APLAR 2025 Travel Award on JCR, The 27th Asia Pacific League of Associations for Rheumatology Congress (APLAR 2025)
  2. MRCR Most Cited Articles 2024