Hirotaka TACHIBANA

Last Updated :2026/04/21

Affiliations, Positions
Research Institute for Radiation Biology and Medicine, Assistant Professor
E-mail
htachibanahiroshima-u.ac.jp
Self-introduction
I am undertaking a investigation to elucidate the molecular mechanisms underlying radiation‑induced carcinogenesis by conducting histological and molecular biological analyses of tissues and tumors derived from experimental mouse models after ionizing radiation exposure.

Basic Information

Major Professional Backgrounds

  • 2026/04, Hiroshima University, Research Institute for Radiation Biology and Medicine, Assistant Professor
  • 2026/04, Central Research Institute of Electric Power Industry, Susteinable System Research Laboratory, Visiting Researcher
  • 2025/04, Tokyo Metropolitan University, Visiting Researcher
  • 2024/04, National Institutes for Quantum Science and Technology, Visiting Researcher
  • 2023/08, 2026/03, Central Research Institute of Electric Power Industry, Biology and Environmental Chemistry Division, Sustainable System Research Laboratory, Research Scientist
  • 2022/04, 2024/03, National Institutes for Quantum and Radiological Science and Technology
  • 2023/04, 2023/07, Central Research Institute of Electric Power Industry, Biology and Environmental Chemistry Division, Sustainable System Research Laboratory, Research Scientist
  • 2021/04, 2023/03, Chiba University, Graduate School of Science, JSPS Research Fellow
  • 2019/04, 2021/03, National Institutes for Quantum and Radiological Science and Technology

Educational Backgrounds

  • Chiba University, 2017/04, 2022/03
  • Toho University, Faculty of Science, Department of Biomolecular Science, 2013/04, 2017/03

Affiliated Academic Societies

  • Radiation Research Society, 2024/04
  • Japanese Society of Health Physics, 2023/07
  • The Molecular Biology Society of Japan, 2022/10
  • Japan Society for Biomedical Gerontology, 2022/06
  • The Japanese Society for Biological Sciences in Space, 2019/07
  • Japanese Cancer Association, 2018/05
  • The Japanese Radiation Research Society, 2017/06

Research Activities

Academic Papers

  1. Genomic and transcriptomic characterization of gamma ray– and heavy ion–induced precursor B-cell lymphomas in B6C3F1 mice: Radiation type-dependent interstitial chromosomal deletions at tumor-suppressor gene loci, Carcinogenesis, 20260116
  2. Importance of radiation-induced stem cell competition in the intestine, Radiation Biology Research Communications, 59(1), 58-74, 202403
  3. Azithromycin induces read-through of the nonsense Apc allele and prevents intestinal tumorigenesis in C3B6F1 Apc/+ mice, Biomedicine & Pharmacotherapy, 164, 114968-114968, 202308
  4. Interstitial deletion of the Apc locus in β-catenin-overexpressing cells is a signature of radiation-induced intestinal tumors in C3B6F1 ApcMin/+ mice†., Journal of radiation research, 64(3), 622-631, 20230525
  5. Genomic profile of radiation-induced early-onset mouse B-cell lymphoma recapitulates features of Philadelphia chromosome-like acute lymphoblastic leukemia in humans., Carcinogenesis, 43(7), 693-703, 20220830
  6. Early induction and increased risk of precursor B-cell neoplasms after exposure of infant or young-adult mice to ionizing radiation., Journal of radiation research, 61(5), 648-656, 20200908

Awards

  1. 2022/10, Poster Award, Planning and Acting Network for Low Dose Radiation Research (PLANET)

External Funds

Acceptance Results of Competitive Funds

  1. 2024/04/01, 2028/03/31
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  2. 2025/04, 2026/03
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  3. 2025/04, 2026/03
  4. 2023/04, 2026/03
  5. Grants-in-Aid for Scientific Research Grant-in-Aid for JSPS Fellows, Study on the initial process of B-cell leukemogenesis by ionizing radiation exposure, 2021/04/28, 2023/03/31
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