広島大学

Basic Information

Academic Degrees

• Hiroshima University

Educational Activity

• [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine
• [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Medicine

Research Fields

• Medicine,dentistry, and pharmacy;Clinical surgery;Otorhinolaryngology

Research Keywords

• head and neck cancer, swallowing function study

Affiliated Academic Societies

• The Oto-Rhino-Laryngological Society of Japan, Japan society for head and neck surgery, Japan society for head and neck cancer, The Japan broncho-esophagological society, The society of practical otolaryngology

Educational Activity

Course in Charge

1. 2025, Undergraduate Education, Year, Clinical diagnosis and treatment II
2. 2025, Undergraduate Education, Intensive, Practice of Medicine I
3. 2025, Undergraduate Education, Intensive, Practice of Medicine II
4. 2025, Undergraduate Education, 2Term, Otorhinology
5. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Otorhinolaryngology,Head and Neck Surgery
6. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Otorhinolaryngology,Head and Neck Surgery
7. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Otorhinolaryngology,Head and Neck Surgery
8. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Otorhinolaryngology,Head and Neck Surgery

Research Activities

Academic Papers

1. Pneumococcal conjugate vaccines reduce myringotomy with tympanostomy tube insertion in young children in Japan, Laryngoscope investigative otolaryngology, 2022
2. Association Between Subjective Voice Assessment and Psychological Distress After Thyroidectomy, Journal of Perianesthesia nursing, 2022
3. Utility of plasma circulating tumor DNA and tumor DNA profiles in head and neck squamous cell carcinoma, SCIENTIFIC REPORTS, 2022
4. Effectiveness of Expanded Instantaneous Input Dynamic Range Adjustment on Speech Perception, 2022
5. Deep Association between Transglutaminase 1 and Tissue Eosinophil Infiltration Leading to Nasal Polyp Formation and/or Maintenance with Fibrin Polymerization in Chronic Rhinosinusitis with Nasal Polyps, 2022
6. Determining Invasion Depth in Superficial Pharyngeal Carcinoma by Transoral Ultrasonography, LARYNGOSCOPE, 2022
7. Nitric oxide synthase-2 (CCTTT)n polymorphism is associated with local gene expression and clinical manifestations in patients with chronic rhinosinusitis, 2022
8. Impact of Preventive Measures on Subjective Symptoms and Antigen Sensitization against Japanese Cedar, Cypress Pollen and House Dust Mites in Patients with Allergic Rhinitis: A Retrospective Analysis in the COVID-19 Era, ATMOSPHERE, 2022
9. Co-Expression and Localization of Angiotensin-Converting Enzyme-2 (ACE2) and the Transmembrane Serine Protease 2 (TMPRSS2) in Paranasal Ciliated Epithelium of Patients with Chronic Rhinosinusitis, AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 2022
10. Examination of micro-superficial lesions of up to 5 mm in size in the pharyngeal region, J Laryngol Oto, 202208
11. Swallowing function after transoral surgery for laryngopharyngeal cancer, PLoS One, 2022
12. Utility of plasma circulating tumor DNA and tumor DNA profiles in head and neck squamous cell carcinoma, Sci Rep, 202206
13. Distinct Gene Set Enrichment Profiles in Eosinophilic and Non-Eosinophilic Chronic Rhinosinusitis with Nasal Polyps by Bulk RNA Barcoding and Sequencing, Int J Mol Sci., 202205
14. A Case of Primary Osteosarcoma of the Mandible That Responded to Preoperative Chemotherapy: p16 as a Potential Prognostic Factor, Acta Med Okayama, 202204
15. ★, Severe multiple simultaneous immune-related adverse events in a patient with head and neck cancer, Auris Nasus Larynx, 202202
16. Association between subjective voice Assessment and psychological distress after thyroidectomy, Journal of perianesthesia nursing, 202202
17. Pneumococcal conjugate vaccines reduce myringotomy with tympanostomy tube insertion in young children in Japan, LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY, 7(1), 259-265, 202202
    Link to Paper Search Results by DOI
18. Nitric oxide synthase-2 (CCTTT)n polymorphism is associated with local gene expression and clinical manifestations in patients with chronic rhinosinusitis, EUROPEAN JOURNAL OF INFLAMMATION, 20, 20220101
    Link to Paper Search Results by DOI
19. Differential expression of angiotensin-converting enzyme-2 in human paranasal sinus mucosa in patients with chronic rhinosinusitis, JOURNAL OF LARYNGOLOGY AND OTOLOGY, 135(9), 773-778, 202109
    Link to Paper Search Results by DOI
20. The Functional Diversity of Nitric Oxide Synthase Isoforms in Human Nose and Paranasal Sinuses: Contrasting Pathophysiological Aspects in Nasal Allergy and Chronic Rhinosinusitis, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(14), 202107
    Link to Paper Search Results by DOI
21. Baseline Neutrophil-to-Lymphocyte Ratio and Glasgow Prognostic Score are Associated with Clinical Outcome in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Treated with Nivolumab, ACTA MEDICA OKAYAMA, 75(3), 335-343, 202106
22. Identification of a Novel Copy Number Variation of EYA4 Causing Autosomal Dominant Non-syndromic Hearing Loss, OTOLOGY & NEUROTOLOGY, 42(7), E866-E874, 202108
    Link to Paper Search Results by DOI
23. ★, A long survival patient of anaplastic thyroid carcinoma treated with lenvatinib, Auris Nasus Larynx, 2020
24. A Case Report of Bulky Venous Malformation in the Parapharyngeal Space, International Journal of Practical Otolaryngology, 2020
25. Lacrimal Gland Adenocarcinoma with Apocrine Metaplasia: A Case Report, Journal of Head and Neck Surgery, 2019
26. A Single Institution's Experience of Definitive Radiotherapy Using Volumetric-modulated Arc Therapy for Hypopharyngeal Cancers, ANTICANCER RESEARCH, 40(7), 4183-4190, 202007
    Link to Paper Search Results by DOI
27. Increased Tissue Expression of Lectin-Like Oxidized LDL Receptor-1 (LOX-1) Is Associated with Disease Severity in Chronic Rhinosinusitis with Nasal Polyps, DIAGNOSTICS, 10(4), 202004
    Link to Paper Search Results by DOI
28. Extra-axial chordoma of the gingiva, AURIS NASUS LARYNX, 47(2), 299-304, 202004
    Link to Paper Search Results by DOI
29. Baseline neutrophil-to-lymphocyte ratio (NLR) is associated with clinical outcome in recurrent or metastatic head and neck cancer patients treated with nivolumab, Acta Oto-Laryngologica, 2019
30. ★, Evaluation of role of prophylactic swallowing rehabilitation in chemoradiotherapy for advanced head and neck cancer using novel software analysis of videofluorography images, Hirosihma Journal of Medical Sciences, 68(2.3), 27-34, 2019
31. Ganglioneuroma in the neck region: a case report, Hiroshima Journal of Medical Sciences, 68(2.3), 49-53, 2019
32. Efficacy of anti-PD-1 therapy in a patient with brain metastasis of parotid carcinoma: A case report, AURIS NASUS LARYNX, 46(5), 813-817, 201910
    Link to Paper Search Results by DOI
33. Nasal nitric oxide in the inferior turbinate surface decreases with intranasal steroids in allergic rhinitis: A prospective study, AURIS NASUS LARYNX, 46(4), 507-512, 201908
    Link to Paper Search Results by DOI
34. Low-dose dexamethasone with fosaprepitant and palonosetron to prevent cisplatin-induced nausea and vomiting in head and neck cancer patients, ACTA OTO-LARYNGOLOGICA, 138(10), 921-925, 2018
    Link to Paper Search Results by DOI
35. Management of Intractable Nasal Hyperreactivity by Selective Resection of Posterior Nasal Nerve Branches, Int J Otolaryngol
36. Extraskeletal osteosarcoma in the parotid gland: A case report, Auris Nasus Larynx, 45(3), 644-647, 2018
37. ★, Nine cases of carcinoma with neuroendocrine features in the head and neck: clinicopathological characteristics and clinical outcomes, Jpn J Clin Oncol,, 45(4), 328-335, 2015
38. Age-dependent changes in the expression of klotho protein, TPRV5 and TRPV6 in mouse inner ear., Acta Otolaryngol, 129(12), 1340-1350, 2009
39. Expression of transient receptor potential vanilloid (TRPV) families 1, 2, 3 and 4 in the mouse olfactory epithelium., Rhinology, 47(3), 242-247, 2009
40. Expression of transient receptor potential channel melastin (TRPM) 1-8 and TRPA1 (ankyrin) in mouse inner ear., Acta Otoralyngol, 129(10), 1050-1060, 2009
41. ★, Localization of transient receptor potential vanilloid in the human larynx., Acta Otoralyngol, 129(5), 560-568, 2009
42. ★, Localization of transient receptor potential channel vanilloid subfamilies in the mouse larynx, Acta Otolaryngol, 128(6), 685-693, 2008

Invited Lecture, Oral Presentation, Poster Presentation

1. Safety Study of Percutaneous Sensory Nerve Stimulation in Patients with Head and Neck Cancer Undergoing Chemoradiotherapy, 2023/01/18, Without Invitation, English, published
2. Localization of transient receptor potential channel vanilloid subfamilies in the larynx., Hamamoto T, Takumida M, Hirakawa K, et al, 2008, Without Invitation, English
3. Nine cases of carcinoma with neuroendocrine features in the head and neck, Hamamoto. T, Hayashi R, Fujii S, et al, 2th Congress of Asian Society of Head and Neck Oncology, 2013, Without Invitation, Japanese
4. Clinical Study of Parotid Cancer, Hamamoto. T, Hirakawa K, Takeno S, et al., 4th Congress of Asian Society of Head and Neck Oncology, 2015, Without Invitation, Japanese

External Funds

Acceptance Results of Competitive Funds

1. 2022/04/01, 2025/03/31
2. 2019/04/01, 2023/03/31
3. 2009
4. 2006
5. 2016, 2018

Social Activities

History as Peer Reviews of Academic Papers

1. 2021, American Journal of Case Reports, Others
2. 2020, Current Oncology, Others, 1
3. 2020, JCM, Others
4. 2020, Archives of Otolaryngology and Rhinology, Others
5. 2017, SAGE Open Medical Case Reports, Others
6. 2019, BMJ Case Reports, Others