EISO HIYAMA
Last Updated :2025/01/07
- Affiliations, Positions
- Natural Science Center for Basic Research and Development, Professor (Special Appointment)
- E-mail
- eisohiroshima-u.ac.jp
Basic Information
Academic Degrees
- Medical Doctor, Hiroshima University
Research Fields
- Medicine,dentistry, and pharmacy;Clinical internal medicine;Pediatrics
- Medicine,dentistry, and pharmacy;Clinical surgery;Pediatric surgery
Research Keywords
- Digestive Organ
- Immortalization
- Cancer
- Oncogene
- Telomere
- microarray
- Oncogene
- Neuroblastoma
- Telomerase
Educational Activity
Course in Charge
- 2024, Undergraduate Education, Intensive, Practice of Medicine I
- 2024, Undergraduate Education, Intensive, Practice of Medicine II
- 2024, Graduate Education (Master's Program) , First Semester, Seminar
- 2024, Graduate Education (Master's Program) , Second Semester, Seminar
- 2024, Graduate Education (Master's Program) , First Semester, Research
- 2024, Graduate Education (Master's Program) , Second Semester, Research
- 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar
- 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar
- 2024, Graduate Education (Master's Program) , First Semester, Basic Human Genetics Practice
Research Activities
Academic Papers
- Neoplastic transformation by TERT in FGF-2-expanded human mesenchymal stem cells, INTERNATIONAL JOURNAL OF ONCOLOGY, 39(1), 5-11, 201107
- Telomerase activation without shortening of telomeric 3 '-overhang is a poor prognostic factor in human colorectal cancer, CANCER SCIENCE, 102(2), 330-335, 201102
- Impact of Intratumoral Thymidylate Synthase Expression on Prognosis After Surgical Resection for Ampullary Carcinoma, JOURNAL OF SURGICAL ONCOLOGY, 103(7), 663-668, 20110601
- New method for absolute spinal cord ischemia protection in rabbits, JOURNAL OF VASCULAR SURGERY, 54(4), 1109-1116, 201110
- Wnt signaling and telomerase activation of hepatoblastoma: correlation with chemosensitivity and surgical resectability, JOURNAL OF PEDIATRIC SURGERY, 46(12), 2221-2227, 201112
- Histological Loss of Pancreatic Exocrine Cells Correlates With Pancreatic Exocrine Function After Pancreatic Surgery, PANCREAS, 41(6), 928-933, 201208
- Prognostic Significance of Telomerase Activity and Human Telomerase Reverse Transcriptase Expression in Ampullary Carcinoma, ANNALS OF SURGICAL ONCOLOGY, 19(9), 3072-3080, 201209
- Telomerase in tumorigenesis and development of solid neoplasias., 13(13), 1515-1520, 19950901
- Cellular immortalization and telomerase, 14(4), 551-556, 19960401
- Telomerase and Human Diseases, 51(8), 1508-1511, 19960801
- Telomerase in Development and Differentiation, 51(11), 2255-2259, 19961101
- Telomerase -Detection of Telomerase Activity and Its Clinical Implication-, Biotherapy, 11(1), 67-74, 19970101
- Activation of Telomerase in Hematopoietic Progenitor Cells and Lymphocytes, 52(3), 379-384, 19970301
- Telomerase and Early Detection of Cancer, 23(1), 21-24, 19970101
- Telomere and Telomerase in Human Cancer, 24(2), 196-201, 19970101
- Telomerase Activity in Neuroblastoma, 29(3), 445-451, 19970301
- Telomerase activity in adult and childhood solid malignant tumors., Surgery Frontier, 4(1), 29-36, 19970401
- Telomerase activity as a novel marker of lung cancer, 56(5), 1253-1257, 19980501
- Application of telomerase inhibitors for gastrointestinal cancer therapy, 184(12), 907-911, 19980301
- Relationship between telomere length and clinical and biological characteristics of the cancer with telomerase reactivation, 56(5), 1139-1145, 19980501
- Advance of research on telomerase, 25(8), 1105-1110, 19980701
- Telomerae activity in cancers of digestive organs, 59(8), 911-916, 19970801
- Telomerase as a novel target for anticancer therapy, Molecular Medicine, 35(11), 1374-1382, 19981001
- N-myc gene amplification and other prognosis -associated factors in neuroblastoma, J. Pediatric Surgery, 19900401
- Neuroblastoma with DNA amplification and rearrangement in N-myc gene region, Cancer Research, 1946-1651, 19900401
- Immunohistochemical analysis of N-myc protein expression in neuroblastoma, Journal of Pediatric Surgery, 838-843, 19910401
- Length of telomeric in neuroblastoma, Japanese Journal of Cancer Research, 153-164, 19920401
- Length of telomeric repeats in neuroblastoma, Journal of Experimental Medicine, 205, 19930401
- Alteration of telomeric repeat length in adult and childhood neoplasias, INTERNATIONAL JOURNAL OF ONCOLOGY, 6, 13-16, 19950401
- Surgical management of tracheal ageuesis, Journal of thoracic cardiovascular Surgery, 108, 830-833, 19940401
- Alterations in telomeric repeat length in lung cancer are associated with loss of hererozygosity in p53 and Rb, Oncogene, 10, 937-944, 19950401
- Alteration of telomeric repear length in neuroblaetoma, Japanese Journal of Pediatrie Surgery, 27(5), 508-513, 19950401
- Alterations of telomere length in neuroblastoma., Journal of Experimental Medicine, 164, 205, 19930401
- pulmonary hyper tension with portal hypertension., Journal of Experimental Medicine, 164, 205, 19930401
- emergent CT scan for abdominal injury in children, Japanese Journal of Pediatric Surgery, 25, 38-45, 19930401
- Cancer-cell proliferation and alteration in length of telomeric repeats. Tiss., Cult. Res. Commun=, 12, 291-7, 19930401
- Treatments for MRSA infections in pediatric surgery, Journal of Clinical Surgery, 48, 759-66, 19930401
- Asepetic surgery in children, Medicament News, 1287, 2-7, 19930401
- Antibacterial therapy against surgical infections, Antibiotics and chemotherapy, 9, 2120-30, 19930401
- Postoperative infections and multiple organ failure, Surgery Frontier, 1, 29-36, 19940401
- Pseudomonas infections in surgical patients, 18, 19-22, 19940401
- Treatments for prevention of postoperative infections., Gastroenterological Surgery, 17, 19-25, 19940401
- Immarlodeficiency in elder patients and treatments for Surgical infection in these patients, Gastroenterological Surgery, 17, 1577-84, 19940401
- Bacterial translocation and multiple organ failure, 18, 259-63, 19940401
- trk A gene expression in neuroblastoma., Cancer, 76, 1085-6, 19950401
- Alteration in length of telomeric repeats in lung Cancer., Lung Cancer, 11, 29-41, 19940401
- Mac-1 expression and superoxide feneration of the peripheral polymorphonuclear leukocyte following gastrectomy and esophagectomy., Hiroshima Journal of Medical Science, 44, 39-46, 19950401
- Telomerase activity in small-cell and non-small-cell lung cancers., J ournal of the National Cancer Institute, 87, 895-902, 19950401
- Activation if telomerase in humar lymphocytes and hematopoietic progenitor cells., Journal of Immunology, 155, 3711-5, 19950401
- Advances in cytokine and anticytokine treatments for sepsis, with special reference to G-CSF replacement therapy., Current Opinion in Surgical Infection, 3, 91-8, 19950401
- Purulent liver abscess., The Japanese Journal of Clinical Medicine, 別冊, 39-42, 19950401
- telomeric repeat lengths and prognosis in heuroblastoma, Japanese Journal of Pediatric Surgery, 27, 508-13, 19950401
- Causatire organisms and toxins of peritonitis, Surgery, 57, 1388-91, 19950401
- Penicillins for surgical infections, 95, 56-60, 19950401
- G-CSF treatments for severe infections, Surgery Frontier, 2, 295-99, 19950401
- Telomerase activity in solid cancers., 13, 1515-20, 19950401
- SIRS in surgery, Gastroenterological Surgery, 18, 159-66, 19950401
- Basic cares of postoperative patients, Journal of Clinical Surgery, 50, 418-9, 19950401
- Activation of Telomerase in Hematopoietic Progenitor Cells and Lymphocytes, 52(3), 81-86, 19970401
- Telomere and telomerase in lung cancer for a new target of therapy., 86(1), 95-99, 19970401
- Telomerase in Development and Differentiation, 51(11), 117-121, 19960401
- Telomerase and Human Diseases, 51(8), 148-151, 19960401
- Telomerase activity in adult and Childhood Solid malignant tumors., Surgery Frontier, 4(1), 29-36, 19970401
- Telomere and telomerase in cancer, 24(2), 196-201, 19970401
- Cell immortalization and telomerase, 14(4), 551-556, 19960401
- Telomerase activity as a novel marker of lung cancer, 56(5), 1253-1257, 19980401
- Telomerase activity as a novel marker of lung cancer and immune-associated lung diseases., Int. J. Mol. Med., 1(3), 545-549, 19980401
- Telmerae activity in cancers of digestive organs, 59(8), 911-916, 19970401
- Relationship between telomere length and clinical and biological characteristics of the cancer with telomerase reactivation, 56(5), 1139-1145, 19980401
- Advance of research on telomerase, 25(8), 1105-1110, 19980401
- Telomerase activity in neuroblastoma : is it a prognostic indicator of clinical behaviour?, Eur. J. Cancer, 33(12), 1932-1936, 19970401
- Application of telomerase inhibitors for gastrointestinal cancer therapy, 184(12), 907-911, 19980401
- Telomere length for cancer diagnosis., 27(3), 245-254, 19980401
- Differential diagnosis of acute abdomen, Current Therapy, 17(4), 621-626, 19990401
- Application of telomerase for diagnosis and treatment of cancer, Surgery, 60(12), 1653-1658, 19980401
- Emerging of vancomycin resistant hospital strains-mechanism of vancomycin resistant expression, Surgery Frontier, 6(1), 49-53, 19990401
- Telomerase as a novel target for anticancer therapy, Molucular Medicine, 35(11), 1374-1382, 19980401
- Design and management for medical field, 75(10), 2104-2108, 19980401
- Surgical soft tissue infection-infected atheroma, perifollicaulitis(furuncle, furunculosis, carbuncle), cellulitis, Surgical Therapy, 79, 392-397, 19980401
- Age-related clanges in immune functions, 10(2), 111-117, 19980401
- Telomerase activity in human cancers, 6(6), 605-610, 19980401
- Administrations of prophylactic antibiotics for high risk patients, Surgery, 60(8), 870-875, 19980401
- Acute gastric mucosal lesion and bacterial translocation, 22(13), 1954-1958, 19980401
- Antibacterial treatment for infections by multidrug-resistant strains, Intersive & Critical Care Medicine, 10(11), 1177-1184, 19980401
- Expression of telomerase activity in human endometrium is localized to epithelial glandular cells and regulated in a merstrual phase-dependent manner correlated with cell proliferation., American Journal of Pathdogy, 153(6), 1985-1991, 19980401
- Telomerase activity in digesrive organ cancers, 22(12), 1783-1798, 19990401
- Surgical approaches for pancreatic ascits, Surgery Today, 29(4), 458-461, 19990401
- Genetic analysis with calcium-induced calcium release test in Japanese malignant hyperthermia susceptable(MHS)families, Hiroshima Journal of Medical Science, 48(1), 9-15, 19990401
- Preoperative diagnosis of early pancreatic caranoma with special attention to telomerase activity, 20(9), 765-769, 19990401
- Tolomere and telomerase in human lung cancer, 2(4), 485-492, 19990401
- Lack of CD44 variant 6 expression advanced extrahepatic bile duct/ampullary carcinoma, Cancer, 86(9), 1691-1699, 19990401
- Inhibitory Effect of Telomere-Mimic Phosphorothioate Oligodeoxy Nucleotides (SODNS) on Human Tumor Cell Lines, Orclogy, 57(Suppl.2), 27-36, 19990401
- Telomerase for cancer chiagnosis, 191(3), 227-228, 19990401
- Down-regulation of KAI1 messenger RNA expression is not associated with loss of heterozygosity of the KAI1gene region in lung adenocarcinoma., Japanese Journal of Cancer Resesrch, 90, 970-976, 19990401
- Chromosomal telomere and telomerase in lung asucer, 25(8), 1550-1553, 19990401
- Analysis of mec regulator genes in clinical methicillin-resistant Staphylococcus aureus isolates according to the production of coagulase,types of enterotoxin, and toxic shocl syndrome toxin-1., Hiroshima Journal of Medical Science, 48(2), 49-56, 19990401
- Interleukin-10 expression in intesine of Crohn disease, International Journal of Molecular Medicine, 5(3), 389-395, 20000401
- Generation of pro-inflammatory and anti-inflammatory cytokines in the gut in zymosaninduced peritonitis, Hirosima Journal of Medical Sciences, 49(1), 43-48, 20000401
- Telomerase activity in gastric cancer, Cancer Res., 55(15), 3258-3262, 19950801
- Correlating telomerase activity levels with human neuroblastoma outcomes, Nature Med, 1(3), 249-255, 19950301
- Progression of primary biliary cirrhosis after proctocolectomy for ulcerative colitis., J. Gastroenterol., 35(6), 870-872, 20000601
- High Telomerase Activity Is an Independent Prognostic Indicator of Poor Outcome in Colorectal Cancer., Clinical Cancer Research, 6(10), 2696-2701, 20001001
- Telomerase activity as a marker of breast carcinoma in fine-needle aspirated samples, Cancer Cytopathol, 90(4), 235-8, 20000801
- Multifocal neuroblastoma: biologic behavior and surgical aspects, Cancer, 88(8), 1955-63, 20000401
- Rapid detection of MYCN gene amplification and telomerase expression in neuroblastoma, Clin. Cancer Res., 5(3), 601-9, 19990501
- Telomerase activity as a novel marker of lung cancer and immune-associated lung diseases, Int. J. Mol. Med., 1(3), 545-549, 19980301
- Telomerase activity in rheumatoid synovium correlates with the mononuclear cell infiltration level and disease aggressiveness of rheumatoid arthritis, J.Rheumatol., 25(2), 214-220, 19980201
- Telomerase activity for the preoperative diagnosis of pancreatic cancer, J. Natl. Cancer Inst., 89(21), 1621-1623, 19971101
- Telomerase activity in neuroblastoma: is it a prognostic indicator of clinical behaviour?, Eur. J. Cancer, 33(12), 1932-36, 19970101
- Re: Telomerase activity in human breast tumors [letter], J. Natl. Cancer Inst., 88(12), 839-840, 19960901
- Alterations in telomeric repeat length in lung cancer are associated with loss of heterozygosity in p53 and Rb, Oncogene, 10(5), 937-944, 19950301
- Alteration of telomeric repeat length in adult and childhood solid neoplasias, Int J Oncol, 6(1), 13-16, 19950101
- N-myc gene amplification and other prognosis-associated factors in neuroblastoma, J Pediatr Surg, 25(10), 1095-1099, 19901001
- Frequent deletions and mutations of the beta-catenin gene are associated with overexpression of cyclin D1 and fibronectin and poorly differentiated histology in childhood hepatoblastoma, Clin. Cancer Res., 7(4), 901-8., 20010401
- Kupffer cell function in ischemic and nonischemic livers after hepatic partial ischemia/reperfusion, Surgery Today, 31(2), 140-148, 20010401
- Differential diagnosis of Th1/Th2-response by T-cell and monocyte function between sepsis and non-infectious SIRS via fowcytometry, Critical Care, 5(S1), S28, 20010301
- Immunohistochemical detection of telomerase (hTERT) protein in human cancer tissues and a subset of cells in normal tissues, Neoplasia, 3(1), 17-26, 20010201
- Biological characteristics of neuroblastoma with partial deletion in the short arm of chromosome 1, Medical and Pediatric Oncology, 36(1), 67-74, 20010101
- Telomerase activity as a marker of breast carcinoma in fine-needle aspirated samples, Cancer, 90(4), 235-238, 20000801
- Multifocal Neuroblastoma: Biological Features and Surgical Aspects, Cancer, 88(8), 1955-1963, 20000801
- High Telomerase Activity Is an Independent Prognostic Indicator of Poor Outcome in Colorectal Cancer, Clinical Cancer Research, 6, 2696-2701, 20000701
- Allelotype and loss of heterozygosity around the L-myc gene locus in primary lung cancers, Lung Cancer, 28, 117-125, 20000501
- Interleukin-10 expression in intestine of Crohn disease, International Journal of Molecular Medicine, 5(2), 389-395, 20000401
- Progression of primary biliary cirrhosis after proctocolectomy for ulcerative colitis, J. Gastroenterol., 35, 870-872, 20001101
- Down-regulation of KAI1 messenger RNA expression is not associated with loss of heterozygosity of hte KAI1 gene region in lung adenocarcinoma, Jpn.J.Cancer Res., 90, 970-976, 19990901
- Surgical approaches for pancreatic ascites: report of three cases, Surg Today, 29, 458-461, 19990501
- An additional dose of cefazolin for intraoperative prophylaxis, Surgery Today, 29, 1233-1236, 19991201
- Lack of CD44 variant 6 expression in advanced extrahepatic bile duct/ampullary carcinoma., Cancer, 86(9), 1691-1699, 19991101
- Genetic analysis with calcium-induced calcium release test in Japanese malignant hyperthermia susceptable (MHS) families, Hiroshima J. Med. Sci., 48(1), 9-15, 19990301
- Rapid detection of MYCN gene amplification and telomerase expression in neuroblastoma, Clinical Cancer Research, 5, 601-609, 19990301
- Analysis of mec regulator genes in clinical methicillin-resistant Staphylococcus aureus isolates according to the production of coagulase types of enterotoxin and toxic shock syndrome toxin-1., Hiroshima J. Med. Sci., 48(2), 49-56, 19990101
- Inhibitory Effect of Telomere-Mimic Phosphorothioate Oligodeoxy Nucleotides (S-ODNS) on Human Tumor Cell Lines., Oncology, 57(Suppl 2), 27-36, 19990101
- Expression of telomerase activity in human endometrium is localized to epithelial glandular cells and regulated in a menstrual phase-dependent manner correlated with cell proliferation, American Journal Pathology, 153(6), 1985-1991, 19981201
- Age-dependent telomerase shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress, Life Science, 63(11), 935-948, 19981101
- Telomerase activity as a novel marker of lung cancer and immune-associated lung diseases, International Journal of Molecular Medicine, 1, 545-549, 19980301
- Telomerase activity in rheumatoid synovium correlates with mononuclear cell infiltration level and disease aggressiveness of rheymatoid arthritis, Journal of Rheumatology, 25, 214-220, 19980201
- Postoperative enteritis caused by methicillin-resistant Sthaphylococcus aureus, Surgery Today, 27, 816-825, 19970901
- Clinical investigation of neuroblastoma with partial deletion in the short arm of chromosome 1, Clinical Cancer Research, 3, 1221-1228, 19970701
- Telomerase activity for the preoperative diganosis of pancreatic cancer, J ournal of the National Cancer Institute, 89(21), 1621-1623, 19971101
- Telomerase activity is detected in pancreatic cancer but not in benign tumors, Cancer Research, 57, 326-331, 19970101
- Telomerase activity in neuroblastoma: is it a prognostic indicator of clinical behavior, European Journal of Control, 33(12), 1932-1936, 19970101
- Telomerase activity in human intestine, INTERNATIONAL JOURNAL OF ONCOLOGY, 9, 453-458, 19960901
- ★, Telomerase activity in human breast tumors, Journal of National Cancer Institute, 88(2), 116-122, 19960101
- trk A gene expression in neuroblastoma, Cancer, 76, 1086-1095, 19950901
- Severity and predicted outcome of postoperative Pseudomonas aeruginosa infections, Surgery Today, 25, 672-678, 19950801
- ★, Telomerase activity in gastric cancer, Cancer Research, 55(8), 3258-3262, 19950801
- Mac-1 expression and superoxide generation of the peripheral polymorphonuclear leukocyte following gastrectomy and esophagectomy, Hiroshima Journal of Medical Science, 44(2), 39-46, 19950601
- ★, Telomerase activity in small-cell and non-small-cell lung cancers, J ournal of the National Cancer Institute, 87(12), 895-902, 19950601
- Alterations in telomeric repeat length in lung cancer are associated with loss of heterozygosity in p53 and Rb, Oncogene, 10, 937-944, 19950301
- ★, Correlating telomerase activity levels with human neuroblastoma outcomes, Nature Medicine, 1(3), 249-255, 19950301
- Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP), Method in Cell Science, 17, 1-15, 19950101
- Activation of telomerase in human lymphocytes and hematopoietic progenitor cells, Jouranl of Immunology, 155, 3711-3715, 19950101
- Alteration of telomeric repeat length in adult and childhood solid neoplasias, INTERNATIONAL JOURNAL OF ONCOLOGY, 6(1), 13-16, 19950101
- Poor outcome in patients with advanced stage neuroblastoma and coincident opsomyoclonus syndrome, Cancer, 74(6), 1824-1826, 19940901
- Alteration in length of telomeric repeats in lung cancer, Lung Cancer, 11, 29-41, 19940701
- Prognositic Prediction in Neuroblastomas: Clinical significance of combined Analysis for Ha-ras p21 expression and N-myc gene amplification, Cancer Detection and Prevention, 18(4), 283-289, 19940401
- Surgical management of tracheal agenesis, The Japanese Journal of Thoracic and Cardiovascular Surgery, 108(11), 830-833, 19941101
- Generation of pro-inflammatory and anti-inflammatory cytokines in the gut in zymosan-induced peritonitis, Hiroshima Journal of Medical Science, 49(1), 43-48, 20000301
- Long-term survival of peripheral intrahepatic cholangiocarcinoma with metastasis to the para-aortic lymph nodes., Surgery, 126, 105-106, 20000101
- Length of telomeric repeats in neuroblastoma: correlation with prognosis and other biological characteristics, Japanese Journal of Cancer Resesrch, 83(2), 159-164, 19920201
- Immunohistochemical analysis of N-myc protein expression in neuroblastoma: Correlation with prognosis of patients, J Pediatr Surg, 26(7), 838-843, 19910701
- CHARGE association with neuroblastoma, Pediatric Surgery, 5(4), 463-465, 19900401
- N-myc gene amplification and other prognosis-associated factors in neuroblastoma, J Pediatr Surg, 25(10), 1095-1099, 19900101
- Impending gastric rupture in a neonate with gastric outlet obstruction due to malrotation, Hiroshima Journal of Medical Science, 35, 105-107, 19860601
- VIP-producing neruogenic tumors in children: Two case report, Hirosima Journal of Medical Sciences, 33(3), 393-396, 19840901
- A case report of postradiation sarcoma, Hiroshima Journal of Mediacal Science, 33(2), 247-250, 19840601
- Poor Outcome in Patients with Advanced Stage Neuroblastoma and Coincident Opsomyoclonus Syndrome, Cancer, 74(6), 1821-1826, 19940601
- Surgical approachs for pancreatic ascites: report of three cases, Surgery Today, 29(5), 458-461, 19990501
- Multifocal Neuroblastoma, Cancer, 88(8), 1955, 20000801
- Alterations in telomeric repeat length in lung cancer are associated with loss of heterozygosity in p53 and Rb, Oncogene, 10, 937-944, 19950101
- Telomerase and cancer, Human molecular genetics, ?677-685, 20010401
- Clinical utility of telomerase in cancer, Oncogene, in press, 20011201
- Experience with Internatiional Neuroblastoma Staging Systemand Pathology Classification., British Journal of Cancer, 86, 1110-1116, 20021001
- High-dose chemotherapy in children with metastatic hepatoblastoma, Pediatric International, 44, 300-305, 20020401
- Detection of telomerase activity in lung cancer tissues, Humana Press, 1(1), 403-414, 20031001
- Differential gene expression profiles between neuroblastomas with high telomerase activity and low telomerase activity, J Pediatr Surg, 38(12), 1730-1734, 20031201
- Fluorescent-based BAT-26 analysis for distinct screening of microsatellite instability in colorectal cancers, Int J Oncol, 22, 807-813, 20030801
- Relevance of antimicrobial agent-induced endotoxin release from in vitro cultured Escherichia coli and in vivo experimental infection with Gram-negative bacilli, Int J Antimicrob Agents, 21, 463-470, 20030401
- Comparative analysis of K-ras point mutation, telomerase activity, and p53 overexpression in pancreatic tumours, Oncol.Rep., 10, 177-283, 20030301
- Telomerase as tumor marker., Cancer lett., 194, 221-233, 20030601
- Differential gene expressions during immortalization of normal human fibroblasts and endothelial cells transfected with human telomerase reverse transcriptase gene., Int J Oncol, 24, 1435-1442, 20040801
- Clinical surveillance of surgical imipenem-resistant Pseudomonas aeruginosa infection in a Japanese hospital., J Hosp Infect, 56(2), 111-118, 20040201
- Systemic inflammatory response syndrome (SIRS) as a predictor of strangulated small bowel obstruction., Hepatogastroenterology, 51, 1393-1396, 20040701
- An evaluation of laparoscopic cholecystectomy after selective percutaneous transhepatic gallbladder drainage for acute cholecystitis., Gastrointest Endosc, 53, 839-844, 20040901
- Expression profiling and differential screening between hepatoblastomas the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastoma, Oncogene, 23, 5901-5911, 20040901
- Slow-down of age-dependent telomere shortening is executed in human skin keratinocytes by hormesis-like-effects of trace hydrogen peroxide or by anti-oxidative effects of pro-vitamin C in common concurrently with reduction of intracellular oxidative stress., J. Cell. Biochem., 59(6), 588-592, 20040801
- High expression of telomerase is an independent prognostic indicator of poor outcome in hepatoblastoma., Br J Cancer, 91, 972-979, 20040501
- Expression profiling of favorable and unfavorable neuroblastomas, Pediatr Surg Int, 20(1), 33-38, 20040101
- Expression profiling of favorable and unfavorable neuroblastomas., Pediatr Surg Int, 20, 33-38, 20040101
- Differential gene expression profiles between neuroblastomas with high telomerase activity and low telomerase activity., J Pediatr Surg, 38(12), 1730-1734, 20031201
- Differential gene expressions during immortalization of normal human fibroblasts and endothelial cells transfected with human telomerase reverse transcriptase gene., Int J Oncol, 24(6), 1435-1442, 20040601
- Telomerase expression in noncancerous bronchial epithelia is a possible marker of early development of lung cancer., Cancer Res., 65(21), 9623-9627, 20050401
- Telomerase expression in non-cancerous bronchial epithelia is a possible marker of early development of lung cancer, Cancer Research, 65(21), 1-5, 20051101
- Differential regulation of DEC2 among hypoxia-inducible genes in endometrial carcinomas, Oncol. Rep., 17(4), 871-878, 20070401
- EGFR activating aberration occurs independently of other genetic aberrations or telomerase activation in adenocarcinoma of the lung, Oncol. Rep., 17(6), 1405-1411, 20070601
- Selection of a novel drug-response predictor in esophageal cancer: A novel screening method using microarray and identification of IFITMI as a potent marker gene of CDDP response, Int. J. Oncol., 32(2), 413-423, 20080201
- Telomere and telomerase in stem cells, Br. J. Cancer, 96(7), 1020-4, 20070401
- A mathematical model for affymetrix genechip probe level data, JP Journal of Biostatics, 1(3), 1431-1438, 20071101
- Clinical surveillance of surgical imipenem-resistant Pseudomonas aeruginosa infection in a Japanese hospital., Journal of Hospital Infection, 56, 111-118, 20040401
- Expression profiling of favorable and unfavorable neuroblastomas., Pediatr Surg Int, 20, 33-38, 20040401
- Hepatic regeneration promotes engraftment of intraportally transplanted islet cells., Surgery, 137, 612-619, 20050401
- Hepatic regeneration promotes engraftment of intraportally transplanted islet cells., surgery, 612-619, 20050601
- Intracellular cytokine patterns of peripheral blood T cells as a useful indicator of activeness of Crohn's disease., Hiroshima J Med Sci, 1-8, 20050301
- Attenuation of telomerase activity by hammerhead ribozymes targeting human telomerase RNA and telomerase reverse transcriptase in pancreatic carcinoma cells., Hiroshima J Med Sci, 21-27, 20050301
- Slow-down of age-dependent telomere shortening is executed in human skin keratinocytes by hormesis-like-effects of trace hydrogen peroxide or by anti-oxidative effects of pro-vitamin C in common concurrently with reduction of intracellular oxidativestress., J Cell Biochem, 588-597, 20041001
- Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas., Oncogene, 23, 5901-5911, 20040801
- Systemic inflammatory response syndrome (SIRS) as a predictor of strangulated small bowel obstruction., Hepatogastroenterology, 51, 1393-1396, 20041001
- Laparoscopic and open approach in perforated peptic ulcer., Hepatogastroenterology, 51, 1536-1539, 20040901
- An evaluation of laparoscopic cholecystectomy after selective percutaneous transhepatic gallbladder drainage for acute cholecystitis., Gastrointest Endosc, 59, 839-844, 20040601
- Differential gene expressions during immortalization of normal human fibroblasts and endothelial cells transfected with human telomerase reverse transcriptase gene., Int J Oncol, 24, 1435-1442, 20041201
- High expression of telomerase is an independent prognostic indicator of poor outcome in hepatoblastoma., Br J Cancer, 91, 972-979, 20040801
- Postradiation malignant fibrous histiocytoma and osteosarcoma of a patient with high telomerase activities 25:2951-2955, Anticancer Res, 25, 2951-2955, 20050101
- Postradiation malignant fibrous histiocytoma and osteosarcoma of a patient with high telomerase activities, Anticancer Res, 25, 2951-2955, 20050701
- Molecular epidemiology of enteritis-causing methicillin-resistant Staphylococcus aureus, J Hosp Infect, 62, 37-43, 20060101
- Telomerase expression in noncancerous bronchial epithelia is a possible marker of early development of lung cancer, Cancer Res, 65(21), 9623-9627, 20051101
- Diagnostic and prognostic impact of beta-catenin alterations in pediatric liver tumors, Oncology Reports, 15, 551-556, 20060101
- Molecular and biological heterogeneity in neuroblastoma, Current Genomi, 3, 319-332, 20050301
- Prediction of individual response to platinum/paclitaxel combination using novel marker genes in ovarian cancers, Mol Cancer Ther, 5(3), 767-775, 20060301
- Chemosensitivity prediction in esophageal squamous cell carcinoma: Novel marker genes and efficacy-prediction formulae using their expression data, Int J Oncol, 28, 1153-1162, 20060501
- Pretreatment and one-shot separating analysis of whole catecholamine metabolites in plasma by using LC/MS, Anal Bioanal Chem, 385, 814-820, 20060701
- MYCN gene amplification is a powerful prognostic factor even in infantile neuroblastoma detected by mass screening, Br J Cancer, 94, 1510-1515, 20060502
- Single nucleotide polymorphism array analysis to predict clinical outcome in neuroblastoma patients, J Pediatr Surg, 41, 2032-2036, 20061201
- Possibility of selection of chondrogenic progenitor cells by telomere length in FGF-2-expanded mesenchymal stromal cells, Cell Prolif, 39, 575-584, 20060101
- [Bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents--special references to bacteria isolated between April 2003 and March 2004], Jpn J Antibiot, 59, 72-116, 20060401
- Reciprocal expression of CCAAT/enhancer binding proteins alpha and beta in hepatoblastomas and its prognostic significance, Oncol Rep, 17, 341-344, 20070201
- Telomere and telomerase in stem cells, British Journal of Cancer, 96, 1020-1024, 20070401
- Telomere length and telomerase activity in extra-abdominal desmoid tumors, Anticancer Res, 27, 411-415, 20070101
- Differential regulation of DEC2 among hypoxia-inducible genes in endometrial carcinomas, Oncology Reports, 17, 871-878, 20070401
- EGFR activating aberration occurs independently of other genetic aberrations or telomerase activation in adenocarcinoma of the lung, Oncology Reports, 17, 1405-1411, 20070601
- High-dose chemotherapy in children with metastatic hepatoblastoma., Pediatrics International, 44, 300-305, 20020301
- Single nucleotide polymorphism array analysis to predict clinical outcome in neuroblastoma patients, Journal of Pediatric Surgery, 41(12), 2032-2036, 20061201
- Telomerase detection in the diagnosis and prognosis of cancer, Cytotechnology, 45(1-2), 64-74, 20040601
- Exploration of the genes responsible for unlimited proliferation of immortalized lung fibroblasts., Exp Lung Res, 34(7), 373-390, 20080901
- Human mismatch repair gene, MLH1, is transcriptionally repressed by hypoxia-inducible transcription factors, DEC1 and DEC2., Oncogene, 27(30), 4200-4209, 20080701
- EMP3 as a tumor suppressor gene for esophageal squamous cell carcinoma., Cancer Letters, 274(2009), 25-32, 20090201
- Effectiveness of screening for neuroblastoma at 6 months of age: a retrospective population-based cohort study, The Lancet, 371, 1173-1180, 20080401
- EMP3 as a candidate tumor suppressor gene for solid tumors., Expert Opin. Ther. Targets., 13(7), 811-822, 20090701
- Detection of island hypermethylation of caspase-8 in neuroblastoma using an oligonucleotide array., Pediatr Blood Cancer, 52(7), 777-783, 20090701
- Telomere biology in neuroblastoma: telomere binding proteins and alternative strengthening of telomeres., Eur.J.Pediatric, 44(12), 2258-2266, 20091201
- Surgical intervention for patent ductus venosus., Pediatric Surgery Int, 26(10), 2010, 20101001
- Surgical intervention for patent ductus venosus., Pediatric Surgery Int, 26(10), 1025-1030, 20101001
- A robust method for estimating gene expression states using Affymetrix microarray probe level data, BMC Bioinformatics, 11, 20100401
- Bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents--special references to bacteria isolated between April 2009 and March 2010, The Japanese Journal of Antibiotics, 64(3), 125-69, 20110601
- EMP3 as a tumor suppressor gene for esophageal squamous cell carcinoma, Cancer Lett, 274(1), 25-32, 20090201
- Long-term survival of peripheral intrahepatic cholangiocarcinoma with metastasis to the para-aortic lymph nodes, SURGERY, 127(1), 105-106, 200001
- Interleukin-10 expression in intestine of Crohn disease, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 5(4), 389-395, 200004
- Multifocal neuroblastoma - Biologic behavior and surgical aspects, CANCER, 88(8), 1955-1963, 20000415
- Allelotype and loss of heterozygosity around the L-myc gene locus in primary lung cancers, LUNG CANCER, 28(2), 117-125, 200005
- Biological characteristics of neuroblastoma with partial deletion in the short arm of chromosome 1, MEDICAL AND PEDIATRIC ONCOLOGY, 36(1), 67-74, 200101
- High telomerase activity is an independent prognostic indicator of poor outcome in colorectal cancer, CLINICAL CANCER RESEARCH, 6(7), 2696-2701, 200007
- Telomerase activity as a marker of breast carcinoma in fine-needle aspirated samples, CANCER CYTOPATHOLOGY, 90(4), 235-238, 20000825
- Progression of primary biliary cirrhosis after proctocolectomy for ulcerative colitis, JOURNAL OF GASTROENTEROLOGY, 35(11), 870-872, 200011
- Immunohistochemical detection of telomerase (hTERT) protein in human cancer tissues and a subset of cells in normal tissues, NEOPLASIA, 3(1), 17-26, 2001
- Kupffer cell function in ischemic and nonischemic livers after hepatic partial ischemia/reperfusion, SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY, 31(2), 140-148, 2001
- Telomerase and cancer, HUMAN MOLECULAR GENETICS, 10(7), 677-685, 200104
- Clinical utility of telomerase in cancer, ONCOGENE, 21(4), 643-649, 20020121
- High-dose chemotherapy in children with metastatic hepatoblastoma, PEDIATRICS INTERNATIONAL, 44(3), 300-305, 200206
- Fluorescent-based BAT-26 analysis for distinct screening of microsatellite instability in colorectal cancers, INTERNATIONAL JOURNAL OF ONCOLOGY, 22(4), 807-813, 200304
- Successful pre-operative diagnosis of malignant intraductal papillary mucinous tumor of the pancreas by detecting telomerase activity, JOURNAL OF GASTROINTESTINAL CANCER, 31(1-3), 117-121, 2002
- Comparative analysis of K-ras point mutation, telomerase activity, and p53 overexpression in pancreatic tumours, ONCOLOGY REPORTS, 10(2), 277-283, 2003
- Relevance of antimicrobial agent-induced endotoxin release from in vitro cultured Escherichia coli and in vivo experimental infection with Gram-negative bacilli, INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 21(5), 463-470, 200305
- Telomerase as tumor marker, CANCER LETTERS, 194(2), 221-233, 20030515
- Differential gene expression profiles between neuroblastomas with high telomerase activity and low telomerase activity, JOURNAL OF PEDIATRIC SURGERY, 38(12), 1730-1734, 200312
- Clinical surveillance of surgical imipenem-resistant Pseudomonas aeruginosa infection in a Japanese hospital, JOURNAL OF HOSPITAL INFECTION, 56(2), 111-118, 200402
- Expression profiling of favorable and unfavorable neuroblastomas, PEDIATRIC SURGERY INTERNATIONAL, 20(1), 33-38, 200401
- Differential gene expressions during immortalization of normal human fibroblasts and endothelial cells transfected with human telomerase reverse transcriptase gene, INTERNATIONAL JOURNAL OF ONCOLOGY, 24(6), 1435-1442, 200406
- An evaluation of laparoscopic cholecystectomy after selective percutaneous transhepatic gallbladder drainage for acute cholecystitis, GASTROINTESTINAL ENDOSCOPY, 59(7), 839-844, 200406
- Systemic Inflammatory Response syndrome (SIRS) as a predictor of strangulated small bowel obstruction, HEPATO-GASTROENTEROLOGY, 51(59), 1393-1396, 2004
- Laparoscopic and open approach in perforated peptic ulcer, HEPATO-GASTROENTEROLOGY, 51(59), 1536-1539, 2004
- High expression of telomerase is an independent prognostic indicator of poor outcome in hepatoblastoma, BRITISH JOURNAL OF CANCER, 91(5), 972-979, 20040831
- Slow-down of age-dependent telomere shortening is executed in human skin keratinocytes by hormesis-like-effects of trace hydrogen peroxide or by anti-oxidative effects of pro-vitamin C in common concurrently with reduction of intracellular oxidative stress, JOURNAL OF CELLULAR BIOCHEMISTRY, 93(3), 588-597, 20041015
- Telomerase detection in the diagnosis and prognosis of cancer, CYTOTECHNOLOGY, 45(1-2), 61-74, 200401
- Hepatic regeneration promotes engraftment of intraportally transplanted islet cells, SURGERY, 137(6), 612-619, 200506
- Postradiation malignant fibrous histiocytoma and osteosarcoma of a patient, with high telomerase activities, ANTICANCER RESEARCH, 25(4), 2951-2955, 2005
- Molecular and biological heterogeneity in neuroblastoma, CURRENT GENOMICS, 6(5), 319-332, 200508
- Telomerase expression in noncancerous bronchial epithelia is a possible marker of early development of lung cancer, CANCER RESEARCH, 65(21), 9623-9627, 20051101
- Molecular epidemiology of enteritis-causing methicillin-resistant Staphylococcus aureus, JOURNAL OF HOSPITAL INFECTION, 62(1), 37-43, 200601
- Diagnostic and prognostic impact of beta-catenin alterations in pediatric liver tumors, ONCOLOGY REPORTS, 15(3), 551-556, 200603
- Prediction of individual response to platinum/paclitaxel combination using novel marker genes in ovarian cancers, MOLECULAR CANCER THERAPEUTICS, 5(3), 767-775, 200603
- Chemosensitivity prediction in esophageal squamous cell carcinoma: Novel marker genes and efficacy-prediction formulae using their expression data, INTERNATIONAL JOURNAL OF ONCOLOGY, 28(5), 1153-1162, 200605
- MYCN gene amplification is a powerful prognostic factor even in infantile neuroblastoma detected by mass screening, BRITISH JOURNAL OF CANCER, 94(10), 1510-1515, 20060522
- Pretreatment and one-shot separating analysis of whole catecholamine metabolites in plasma by using LC/MS, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 385(5), 814-820, 200607
- Telomere and telomerase in stem cells, BRITISH JOURNAL OF CANCER, 96(7), 1020-1024, 20070410
- Telomere length and telomerase activity in extra-abdominal desmoid tumors, ANTICANCER RESEARCH, 27(1A), 411-415, 2007
- EGFR activating aberration occurs independently of other genetic aberrations or telomerase activation in adenocarcinoma of the lung, ONCOLOGY REPORTS, 17(6), 1405-1411, 200706
- Possibility of selection of chondrogenic progenitor cells by telomere length in FGF-2-expanded mesenchymal stromal cells, CELL PROLIFERATION, 39(6), 575-584, 200612
- Single nucleotide polymorphism array analysis to predict clinical outcome in neuroblastoma patients, JOURNAL OF PEDIATRIC SURGERY, 41(12), 2032-2036, 200612
- Differential regulation of DEC2 among hypoxia-inducible genes in endometrial carcinomas, ONCOLOGY REPORTS, 17(4), 871-878, 200704
- Functional analysis of Src homology 3-encoding exon (exon 2) of p130Cas in primary fibroblasts derived from exon 2-specific knockout mice, GENES TO CELLS, 13(2), 145-157, 200802
- Telomerase activity in giant cell tumors of bone, ANNALS OF SURGICAL ONCOLOGY, 14(10), 2896-2902, 200710
- Heterogeneous subgroups in human neuroblastoma for clinically relevant risk stratification, PEDIATRIC SURGERY INTERNATIONAL, 23(11), 1051-1058, 200711
- Detection of human telomerase reverse transcriptase (hTERT) expression in tissue and pancreatic juice from pancreatic cancer, SURGERY, 143(1), 113-125, 200801
- Telomere shortening and telomerase expression during multistage carcinogenesis of intraductal papillary mucinous neoplasms of the pancreas, JOURNAL OF GASTROINTESTINAL SURGERY, 12(1), 17-28, 200801
- Selection of a novel drug-response predictor in esophageal cancer: A novel screening method using microarray and identification of IFITM1 as a potent marker gene of CDDP response, INTERNATIONAL JOURNAL OF ONCOLOGY, 32(2), 413-423, 200802
- Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression, JOURNAL OF SURGICAL ONCOLOGY, 97(5), 469-475, 20080401
- Effectiveness of screening for neuroblastoma at 6 months of age: a retrospective population-based cohort study, LANCET, 371(9619), 1173-1180, 20080405
- Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2, ONCOGENE, 27(30), 4200-4209, 200807
- Exploration of the genes responsible for unlimited proliferation of immortalized lung fibroblasts, EXPERIMENTAL LUNG RESEARCH, 34(7), 373-390, 2008
- Evaluation of genes identified by microarray analysis in favorable neuroblastoma, PEDIATRIC SURGERY INTERNATIONAL, 25(11), 931-937, 200911
- EMP3 as a tumor suppressor gene for esophageal squamous cell carcinoma, CANCER LETTERS, 274(1), 25-32, 20090208
- Telomere-Maintenance Mechanisms in Soft-Tissue Malignant Fibrous Histiocytomas, JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 91A(4), 928-937, 200904
- Detection of CpG Island Hypermethylation of Caspase-8 in Neuroblastoma Using an Oligonucleotide Array, PEDIATRIC BLOOD & CANCER, 52(7), 777-783, 20090701
- Consensus criteria for sensitive detection of minimal neuroblastoma cells in bone marrow, blood and stem cell preparations by immunocytology and QRT-PCR: recommendations by the International Neuroblastoma Risk Group Task Force, BRITISH JOURNAL OF CANCER, 100(10), 1627-1637, 20090512
- Changes in the agr Locus Affect Enteritis Caused by Methicillin-Resistant Staphylococcus aureus, JOURNAL OF CLINICAL MICROBIOLOGY, 47(5), 1528-1535, 200905
- EMP3 as a candidate tumor suppressor gene for solid tumors, EXPERT OPINION ON THERAPEUTIC TARGETS, 13(7), 811-822, 200907
- Usefulness of Human Telomerase Reverse Transcriptase in Pancreatic Juice as a Biomarker of Pancreatic Malignancy, PANCREAS, 38(5), 527-533, 200907
- Preimplantation Development of Somatic Cell Cloned Embryos in the Common Marmoset (Callithrix jacchus), CLONING AND STEM CELLS, 11(4), 575-583, 200912
- Carcinogenesis and cellular immortalization without persistent inactivation of p16/Rb pathway in lung cancer, INTERNATIONAL JOURNAL OF ONCOLOGY, 36(5), 1217-1227, 201005
- Telomere biology in neuroblastoma: telomere binding proteins and alternative strengthening of telomeres, JOURNAL OF PEDIATRIC SURGERY, 44(12), 2258-2266, 200912
- Telomere Maintenance as Therapeutic Target in Embryonal Tumours, ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 10(3), 196-212, 201003
- A robust method for estimating gene expression states using Affymetrix microarray probe level data, BMC BIOINFORMATICS, 11, 20100412
- Surgical intervention for patent ductus venosus, PEDIATRIC SURGERY INTERNATIONAL, 26(10), 1025-1030, 201010
- Edaravone, a Free Radical Scavenger, Promotes Engraftment of Intraportally Transplanted Islet Cells, PANCREAS, 40(1), 126-130, 201101
- Outcome of hepatoblastomas treated using the Japanese Study Group for Pediatric Liver Tumor (JPLT) protocol-2: report from the JPLT, PEDIATRIC SURGERY INTERNATIONAL, 27(1), 1-8, 201101
- Establishment of ES Cells from Inbred Strain Mice by Dual Inhibition (2i), JOURNAL OF REPRODUCTION AND DEVELOPMENT, 58(1), 77-83, 201202
- Is the prognosis of stage 4s neuroblastoma in patients 12 months of age and older really excellent?, EUROPEAN JOURNAL OF CANCER, 48(11), 1707-1712, 201207
- Clinical feature of anaplastic lymphoma kinase-mutated neuroblastoma, JOURNAL OF PEDIATRIC SURGERY, 47(10), 1789-1796, 201210
- A cisplatin plus pirarubicin-based JPLT2 chemotherapy for hepatoblastoma: experience and future of the Japanese Study Group for Pediatric Liver Tumor (JPLT), PEDIATRIC SURGERY INTERNATIONAL, 29(10), 1071-1075, 201310
- Detection of MYCN amplification using blood plasma: noninvasive therapy evaluation and prediction of prognosis in neuroblastoma, PEDIATRIC SURGERY INTERNATIONAL, 29(11), 1139-1145, 201311
- Hepatoblastoma state of the art: pathology, genetics, risk stratification, and chemotherapy, CURRENT OPINION IN PEDIATRICS, 26(1), 19-28, 201402
- Characterization of common marmoset (Callithrix jacchus) bone marrow-derived mesenchymal stem cells, FOLIA HISTOCHEMICA ET CYTOBIOLOGICA, 51(4), 292-299, 2013
- Towards an international pediatric liver tumor consensus classification: proceedings of the Los Angeles COG liver tumors symposium, MODERN PATHOLOGY, 27(3), 472-491, 201403
- FAST-id system for enrichment of cells with TALEN-induced mutations and large deletions, GENES TO CELLS, 19(5), 419-431, 201405
- Clinical features of ATRX or DAXX mutated neuroblastoma, JOURNAL OF PEDIATRIC SURGERY, 49(12), 1835-1838, 201412
- Balloon-occluded retrograde transvenous obliteration successfully performed for a large gastric varix in combination with temporary occlusion of the splenic artery in a child, ACTA RADIOLOGICA OPEN, 4(3), 201503
- Embolization therapy for bleeding from jejunal loop varices due to extrahepatic portal vein obstruction, MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES, 25(1), 57-61, 20160102
- The (C)under-barhildren's (H)under-barepatic tumors (I)under-barnternational (C)under-barollaboration (CHIC): Novel global rare tumor database yields new prognostic factors in hepatoblastoma and becomes a research model, EUROPEAN JOURNAL OF CANCER, 52, 92-101, 201601
- Direct Lipido-Metabolomics of Single Floating Cells for Analysis of Circulating Tumor Cells by Live Single-cell Mass Spectrometry, ANALYTICAL SCIENCES, 31(12), 1215-1217, 201512
- Circulating free DNA as non-invasive diagnostic biomarker for childhood solid tumors, JOURNAL OF PEDIATRIC SURGERY, 50(12), 2094-2097, 201512
- Mortality and morbidity in primarily resected hepatoblastomas in Japan: Experience of the JPLT (Japanese Study Group for Pediatric Liver Tumor) trials, JOURNAL OF PEDIATRIC SURGERY, 50(12), 2098-2101, 201512
- Nerve Growth Factor Expression Is Not Associated with Perineural Invasion in Extrahepatic Cholangiocarcinoma, DIGESTIVE DISEASES AND SCIENCES, 61(3), 774-784, 201603
- Prognostic value of circulating tumour DNA in patients undergoing curative resection for pancreatic cancer, BRITISH JOURNAL OF CANCER, 115(1), 59-65, 20160628
- Serum-Based Quantification of MYCN Gene Amplification in Young Patients with Neuroblastoma: Potential Utility as a Surrogate Biomarker for Neuroblastoma, PLOS ONE, 11(8), 20160811
- Resectability and tumor response after preoperative chemotherapy in hepatoblastoma treated by the Japanese Study Group for Pediatric Liver Tumor (JPLT)-2 protocol, JOURNAL OF PEDIATRIC SURGERY, 51(12), 2053-2057, 201612
- Telomere biology including TERT rearrangements in neuroblastoma: a useful indicator for surgical treatments, JOURNAL OF PEDIATRIC SURGERY, 51(12), 2080-2085, 201612
- Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration, LANCET ONCOLOGY, 18(1), 122-131, 201701
- Hepatoblastoma state of the art: pathology, genetics, risk stratification, and chemotherapy, Current Opinion in Pediatrics, 26(1), 19-28, 2014
- Clinical prognostic value of DNA methylation in hepatoblastoma: Four novel tumor suppressor candidates, Cancer Science, 107(6), 812-819, 201606
- The Children's Hepatic tumors International Collaboration (CHIC): Novel global rare tumor database yields new prognostic factors in hepatoblastoma and becomes a research model, European Journal of Cancer, 1(52), 92-101, 2015
- Inflammatory myofibroblastic tumors of the lung carrying a chimeric A2M-ALK gene: report of 2 infantile cases and review of the differential diagnosis of infantile pulmonary lesions, HUMAN PATHOLOGY, 66, 177-182, 201708
- Differentiated embryo chondrocyte plays a crucial role in DNA damage response via transcriptional regulation under hypoxic conditions, PLOS ONE, 13(2), 20180221
- 2017 PRETEXT: radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT), PEDIATRIC RADIOLOGY, 48(4), 536-554, 201804
- Sodium Thiosulfate for Protection from Cisplatin-Induced Hearing Loss, NEW ENGLAND JOURNAL OF MEDICINE, 378(25), 2376-2385, 20180621
Publications such as books
- 1999, Bacterial adhesion and growth , 1999
- 2000, Telomerase as a biomarker and prognositc marker in neuroblastoma , Neuroblastoma KEYWORD Pubishing Services Ltd= Barking= England, 2000
- 2000/08, Neuroblastoma , Neuroblastoma KEYWORD Pubishing Services Ltd= Barking= England, 2000, 08, Cocompilation
- Telomere and telomerase in lung cancer , HChiba University=, Scholarly Book, Cocompilation
- 2003/07, Clinical application of microarray as a tool of underestanding cancer biology , Transwprld Research Network, 2003, 07, Scholarly Book, Cocompilation, 18
- 2004/12, Telomerase and lung cancer , Lippincott Williams & Wilkins. Lung Cancer -Principles and practice Third ed., 2004, 12, Textbook, Cocompilation, 934
- 2010/03, Diagnostic and prognostic molecular markers in neuroblastoma. In: Clinical application of molecular diagnosis -cancer, radiation effects, and human diseases-, 2010, 03, Scholarly Book, Compilation, 9788178954080, 220
- 2009/03, Diagnostic Value Ⅰ: Solid Tumors. In: Telomeres and telomerase in cancer, 2009, 03, Scholarly Book, Compilation, 9781603273060, 373
- 2009/03, Role of Telomeres and Telomerase in Cancer. In: Telomeres and telomerase in cancer, 2009, 03, Scholarly Book, Compilation, 9781603273060, 373
- 2009/03, Telomeres and Telomerase in Humans. In: Telomeres and telomerase in cancer, 2009, 03, Scholarly Book, Compilation, 9781603273060, 373
- 2009, Clinical application of molecular diagnosis -cancer, radiation effects, and human diseases- , 2009, Scholarly Book, Compilation, 9788178954080
- 2009/03, Telomere and telomerase for the regulation of stem cells. In: Regulatory Networks in Stem Cells, Humana Press, 2009, 03, Scholarly Book, Cocompilation, 9781603272261, 601
- 2010/03, Public databases useful for molecular diagnosis. In: Clinical application of molecular diagnosis -cancer, radiation effects, and human diseases-, Transworld Research Network, 2010, 03, Scholarly Book, Compilation, 9788178954080 , 220
- 2010/03, Clinical application of molecular diagnosis -cancer, radiation effects, and human diseases-, 2010, 03, Scholarly Book, Compilation, 9788178954080, 220
- 2014, Translational Pediatrics, Pediatric Hepatoblastoma: diagnosis and treatment, 2014, x
Invited Lecture, Oral Presentation, Poster Presentation
- Prediction of prognosis by preoperative chemotherapy response in hepatoblastoma patients treated by JPLT-2 protocol, Hiyama E, Hishiki T, Ida K, Watanabe K, Oue T, Yano M, Hoshino K, Iehara T, Koh K, Tanaka Y, Kurihara S, Ueda Y, SIOP 2015, 2015/10/09, With Invitation, English, Cape Town, South Africa
- Cisplatin plus pirarubicin based chemotherapy for hepatoblastoma: Experience and future in japanese study group for pediatric liver tumor (JPLT), Hiyama E, Kamimatsuse A, ueda Y, Ogura K, Watanabe K, Hishiki T, Tajiri T, Ida K, Yano M, Kondo S, Oue T, Sasaki F, The 7th SIOP Asia Congress, 2012/04/22, Without Invitation, English, Yogyakarta, Indonesia
- Early detection for neuroblastoma: Japanese experience of screening and new strategies for early detection, Hiyama E, Fukuzawa M, Hosoi H, Yano K, Nakayama M, Yoneda A, Iehara T, Masujima T, Ohtaki M, The 7th SIOP Asia Congress, 2012/04/22, Without Invitation, English, Yogyakarta, Indonesia
- Next-generation sequencing: Integrated exotome analysis in human multiple neuroblastoma, Hiyama E, Kamimatsuse A, Ogura K, Ueda Y, Hiyama K, ANR2012, 2012/06/19, Without Invitation, English, Tronto, Canada
- Identification of new candidate biomarkers in progression of neuroblastoma cells using differential transcriptome and proteome analysis, Hiyama E, Kamimatsuse A, Ueda Y, Ogura K, Sueda T, Hiyama K, ANR2012, 2012/06/20, Without Invitation, English, Tronto, Canada
- Echanism of Wnt signal pathway activation in hepatoblastoma, Ueda Y, Kamimatsuse A, Ogura K, Onitake Y, Hiyama K, Hiyama E, SIOP2012, 2012/10/06, Without Invitation, English, London
- ALK activating infant neuroblastoma cases including mass-screening detected cases, Kawashima M, Hiyama E, Kamei N, Kamimatsuse A, Ueda Y, Ogura K, Hiyama K, SIOP2012, 2012/10/06, Without Invitation, English, London
- A genome-wide association study identifies new candidate loci associated with progression of hepatoblastoma in JPLT2 study experience, Hiyama E, SIOP2012, 2012/10/06, Without Invitation, English, London
- FURTHER STUDY: IDENTIFICATION OF NEW CANDIDATE GENES IN PROGRESSION OF HEPATOBLASTOMA USING GENOME-WIDE ASSOCIATION STUDY, Hiyama E, Ueda Y, Onitake Y, Ida K, Ogura K, Kondo S, Kamijyo T, Watanabe K, Oue T, Hishiki T, Tajiri T, Horie H, Inoue T, Tanaka Y, 45th Congress of the International Society of Pediatric Oncology, 2013/09/27, Without Invitation, English, Hong Kong, China
- Detection of Cancer Stem Cells in Childhood Cancers, Hiyama E, BITS 4th Annual World Congress of Molegular & Cel, Without Invitation, English, Dailen, China
- Clinical feature of ATRX or DAXX mutated neuroblastoma, Hiyama E, Kurihara S, Onitake Y, Yamaoka E, Fukuba I, Hiyama K, PAPS2014, 2014/05/25, Without Invitation, English, Calgary, Canada
- Surgical managements for refractory neuroblastoma in young children, Hiyama E, Kurihara S, Onitake Y, Ueda Y, Miki M, Kawaguchi H, Nakamura K, Kobayashi M, BAPS61st Annual Congress, 2014/07/22, Without Invitation, English, Edinburgh, Scotland.
- Outcome and morbidity of primary resection of hepatoblastoma in JPLT-1 and 2 protocols, Hiyama E, Hishiki T, Watanabe K, Ida K, yano M, Oue T, Iehara T, Hoshino K, Koh K, Tanaka Y, Kurihara S., SIOP2014, 2014/10/22, Without Invitation, English, Toronto, Canada
- Molecular diagnosis of lung cancer, Hiyama E, APSR2014, 2014/11/13, Without Invitation, English, Bali. Indonesia
- Telomere biology in neuroblastoma: focusing on alteration of TERT promoter lesion, Hiyama E, Kawashima M, Kurihara S, Ueda Y, Onitake Y, Hiyama K, Advances in Neuroblastoma Research Congress (ANR) 2016, 2016/06/20, Without Invitation, English, Cairns Convention Centre (Queensland, Australia)
- Cancer Fluid Biopsy Using Circulating Tumour Cells and Circulating Free DNA in Childhood Solid Tumors, Hiyama E, Kurihara S, Ueda Y, Kawashima M, Hiyama K, 48th Congress of the International Society of Paediatric Oncology (SIOP), 2016/10/21, Without Invitation, English, Dublin, Ireland
- Two Year Results of a Randomised Phase III Trial for Standard Risk Hepatoblastoma (SR-HB) SIOPEL 6; Cisplatin and Sodium Thiosulfate (STS) Vs Cisplatin Alon, Brock P, Childs M, Rajput K, Maibach R, Brugieres L, Roebuck D, Sullivan M, Laithier V. Rhonge M, dall’Igna P, Hiyama E, Brichard B, Skeen J, Mateos M. E, Capra M, Fabre M, Perilongo G, Czauderna P, Morland B, Neuwelt E., 48th Congress of the International Society of Paediatric Oncology (SIOP), 2016/10/22, Without Invitation, English, Dublin, Ireland
- Surgical Resectability and Tumour Response to Preoperative Chemotherapy in Hepatoblastoma Patients Treated by the Japanese Study Group for Paediatric Liver Tumour (JPLT)-2 Protocol., Hiyama E, Hishiki T, Oue T, Hoshino K, Kurihara S, Kawashima M, Ueda Y, 48th Congress of the International Society of Paediatric Oncology (SIOP), 2016/10/20, Without Invitation, English, Dublin, Ireland
- Congenital Abnormalities and Genetic Backgrounds Associated with Paediatric Malignant Liver Tumour in the Japanese Study Group for Paediatric Liver Tumour, Watanabe K, Hishiki T, Ida K, Oue T, Yano M, Hoshino K, Iehara T, Koh K, Tanaka Y, Hiyama E, 48th Congress of the International Society of Paediatric Oncology (SIOP), 2016/10/20, Without Invitation, English, Dublin, Ireland
- Radiotherapy Quality Management System for Conducting Nationwide Clinical Trials: An Instrument Established by the Japan Chidlren’s Cancer Group, Fuji H, Soejima T, Nozaki M, Masaki H, Nozawa K, Miyazaki O, Kitamura M, Tajiri T, Koshinaga T, Hosoi H, Hiyama E, Takimoto T, Fukuzawa M, Kiyokawa N, Hara J, 48th Congress of the International Society of Paediatric Oncology (SIOP), 2016/10/20, Without Invitation, English, Dublin, Ireland
- Genetic Risk Facotrs of Chemotherapy-Related Ototoxicity and Cardiotoxicity in Hepatoblastoma, Hiyama E, Hishiki T, Ida K, Watanabe K, Oue T, Yano M, Hoshino K, Iehara T, Koh K, Tanaka Y, Kurihara S, Kawashima M, Ueda Y, 48th Congress of the International Society of Paediatric Oncology (SIOP), 2016/10/20, Without Invitation, English, Dublin, Ireland
- NABIGATION SURGERY USING ICG FLUORESCENCE IMAGING FOR HEPATOBLASTOMA LUNG METASECTOMY, Hiyama E, Kurihara S, Ueda Y, Oue T, Kitagawa N, JCCG Liver Tumor Committee(JPLT), Japan, SIOPEL SPRING MEETING 2017, 2017/04/08, Without Invitation, English, Paris, France
- Comprehensive profiling of hepatoblastoma revealed the clinically useful methylation patterns and the ectopic enhancers, 2017/09/28, Without Invitation, Japanese
- DHRS3 and NR0B1 promotes cellular differentiation and growth suppression of neuroblastoma cell lines., 2017/09/29, Without Invitation, English
- PHARMACOGENETICS ANALYSIS for TREATMENT-RELATED TOXICITIES OF HEPATOBLASTOMA PATIENTS IN JAPAN, Hirahara S, Hiyama E, Kimura S,Kuriahra S, Kawashima M, Ueda Y, Onitake Y, The 49th Congress of the International Society of Paediatric Oncology (SIOP2017), 2017/10/13, Without Invitation, English, Washington, DC, USA
- Surgical and Interventional Treatment for ruptured hepatic Tumors in Japanese Study Group Experience, Hiyama E, Hishiki T, Hoshino K, Yokoi A, Tamata T, Kazama T, Honda S, Taguchi T, Kurihara S, Kawashima M, Ueda Y, The 49th Congress of the International Society of Paediatric Oncology (SIOP2017), 2017/10/13, Without Invitation, English, Washington, DC, USA
- Integrated Genetic and Epigenetic Analysis novel Molecular Subgroups in Hepatoblastoma, Hiyama E, Kurihara S, Hirano S, Irisuna F, Ueda Y, Kawashima M, The 49th Congress of the International Society of Paediatric Oncology (SIOP2017), 2017/10/13, Without Invitation, English, Washington, DC, USA
- Sodium Thiosulfate (STS) as Otoprotectant to Reduce the Incidence of Cisplatin-Induced Hearing Loss: Final Results of The SIOPEL6 Trial for Standard Risk Hepatoblastoma (SR-HB), Brock P, Maibach R, Childs M, Rajput K, Fabre M, Roebuck D, Sullivan M, Laithier V, Rhonge M, Dall’lgna P, Hiyama E, Benedicte B, Skeen J, Mateos M, Rangaswami A, Brugieres L, Perliongo G, Czauderna P, Morland B, Neuwelt E, The 49th Congress of the International Society of Paediatric Oncology (SIOP2017), 2017/10/14, Without Invitation, English, Washington, DC, USA
- Survival and Lates Effects of JPLT(Japanese Study Group for Pediatric Liver Tumor)-2 Risk-Stratified Study for Hepatoblastoma, Hiyama E, Hishiki T, Ida K, Watanabe K, Tanaka Y, Aoki Y, Iehara T, Kazama T, Kihira K, Taguchi T, Fujimura J, Hoshino K, Honda S, Matsumoto K, Mori M, Yano M, The 49th Congress of the International Society of Paediatric Oncology (SIOP2017), 2017/10/15, Without Invitation, English, Washington, DC, USA
- Pathological evaluation of ICG navigation surgery for hepatoblastoma pulmonary metastases, Hiyama E, 2018 INTERNATIONAL PEDIATRIC LIVER TUMOR CONFERENCE, 2018/02/16, Without Invitation, English, Houston, TX , USA
- Global clinical trial for childhood liver tumors: PHITT trial, Hiyama E, AMED TR-SPRINT Research Utilization Support Project 3rd Global ARO Network Workshop, 2018/03/07, With Invitation, Japanese, Tokyo
- Telomere biology including rearrangement of TERT promoter lesion in neuroblastoma, Hiyama E, Kawashima M, Kurihara S, Ueda Y, Kimura S, Irisuna A, Morihara N, Hirano S, Hiyama K, Advances in Neuroblastoma Research 2018, 2018/05/12, Without Invitation, English, San Francisco, California, USA
- SingLe cell RNA Sequencing of neuroblastoma, Hiyama E, Kurihara S, Kawashima M, Takemoto M, Ueda Y, Hiyama K, Advances in Neuroblastoma Research 2018, 2018/05/12, Without Invitation, English, San Francisco, California, USA
- Decline of ?-fetoprotein before tumor resection as a prognosis-
predicting factor for hepatoblastoma, Eiso Hiyama, 2018 PAPS meeting, 2018/05/17, Without Invitation, English, Sapporo, Hokkaido
- Cancer fluid biopsy using circulating tumor cells in childhood solid tumors, Yuka Ueda, Eiso Hiyama, Sho Kurihara, Masumi Kawashima, Masato Kojima, Satoshi Hirahara, Keiko Hiyama, 2018 PAPS meeting, 2018/05/14, Without Invitation, English, Sapporo, Hokkaido
- Surgical intervention for portosystemic venous shunt in children, Kurihara S, Hiyama E, Ueda Y, Kawashima M, Kojima M, Hirahara S, 2018 PAPS meeting, 2018/05/15, Without Invitation, Japanese, Sapporo, Hokkaido
- Survival and delayed effects of risk-stratified hepatoblastoma patients treated in the JPLT-2 trial, Hiyama E, Kurihara S, Ueda Y, Hishiki T, Ida K, Iehara T, Oue T, Yano M, Watanabe K, Hoshino K, Ko K, Tanaka Y, 2018 ASCO Annual Meeting, 2018/06/02, Without Invitation, English, Chicago, USA
- Genomic landscape of hepatoblastoma, Aburatani H, Nakagawa H, Hiyama E, 2018/09/28, Without Invitation, English
- Clinical limitations, implications and ethical considerations of genetic analysis in hereditary tumors, Hiyama E, 第77回日本癌学会学術集会, 2018/09/28, Without Invitation, English
- Comprehensive analysis of Hepatoblastoma, Yamamoto S, Tatsuno K, Nagae G, Fujita M, Nakagawa H, Hiyama E, Aburatani H, 2018/09/28, Without Invitation, English, Osaka, Japan