Shigehiro Ono

Last Updated :2024/10/01

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Dentistry & Oral Health Sciences), Assistant Professor
E-mail
onoshigehiroshima-u.ac.jp
Self-introduction
Shigehiro Ono, DDS, Ph.D, FIBCSOMS

Basic Information

Major Professional Backgrounds

  • 2003/10/01, 2007/03/31, Hiroshima University Graduate School of Biomedical Sciences, Assistant Professor
  • 2007/04/01, 2012/03/31, Hiroshima University Graduate School of Sciences, Oral and Maxillofacial Surgery, Assistant Professor
  • 2011/04/04, 2012/03/16, Hannover Medical School, Dept. of Craniomaxillofacial Surgery, researcher
  • 2012/04/01, 2019/03/31, Institute of Biomedical and Health Sciences, Hiroshima University, Department of Oral and Maxillofacial Surgery, Assistant Professor
  • 2019/04/01, Hiroshima University, Graduate School of Biomedical & Health Sciences, Assistant Professor

Educational Backgrounds

  • Hiroshima University, Graduate School, Division of Dental Research, Japan, 1998/04, 2002/03
  • Hiroshima University, Faculty of Dentistry, Japan, 1992/04, 1998/03

Academic Degrees

  • Doctor of Philosophy in Dental Science, Hiroshima University

Educational Activity

  • [Bachelor Degree Program] School of Dentistry : Program of Dentistry : Dentistry
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Dental Sciences

In Charge of Primary Major Programs

  • Dentistry

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Surgical dentistry

Research Keywords

  • Jaw Deformity
  • Onco-pathology
  • Implantology

Affiliated Academic Societies

  • Japanese Society of Oral and Maxillofacial Surgery
  • Japanese Society for Jaw Deformities
  • Japanese Society of Oral Oncology
  • Japanese Association for Oral Infectious Diseases
  • Hiroshima University Dental Society

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, 1Term, Oral and Maxillofacial Surgery I
  2. 2024, Undergraduate Education, 2Term, Oral and Maxillofacial Surgery II
  3. 2024, Undergraduate Education, First Semester, Dental Research Practices I
  4. 2024, Undergraduate Education, 3Term, Basic Practice of Oral and Maxillofacial Medicine III
  5. 2024, Undergraduate Education, 4Term, Basic Practice of Oral and Maxillofacial Medicine IV
  6. 2024, Undergraduate Education, 3Term, Clinical Anatomy for Dentistry I
  7. 2024, Undergraduate Education, 4Term, Clinical Anatomy for Dentistry II
  8. 2024, Undergraduate Education, 3Term, Practice of Clinical Anatomy for Dentistry I
  9. 2024, Undergraduate Education, 4Term, Practice of Clinical Anatomy for Dentistry II
  10. 2024, Undergraduate Education, Second Semester, Dental Research Practices II
  11. 2024, Undergraduate Education, 2Term, Advanced Course in Applied Oral Biology and Medicine
  12. 2024, Undergraduate Education, 2Term, Advanced Course in Oral and Maxillofacial Medicine
  13. 2024, Undergraduate Education, 2Term, General Dentistry III
  14. 2024, Undergraduate Education, First Semester, Dental Research Practices III
  15. 2024, Undergraduate Education, Academic Year, Clinical Practice (Oral Surgery II)
  16. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Oral and Maxillofacial Surgery
  17. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Oral and Maxillofacial Surgery
  18. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Oral and Maxillofacial Surgery
  19. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Oral and Maxillofacial Surgery

Research Activities

Academic Papers

  1. Surgical Orthodontic Treatment for Skeletal Maxillary Protrusion in Sturge-Weber Syndrome, Cureus, 16(5), e59964, 20240509
  2. Correction of Severe Skeletal Class II High Angle with Mandibular Retrusion and Gummy Smile by Double-Jaw Surgery., Correction of Severe Skeletal Class II High Angle with Mandibular Retrusion and Gummy Smile by Double-Jaw Surgery., 63(4), 177-187, 20230111
  3. ACE2 expression and spike S1 protein-mediated immune responses in oral mucosal cells, Oral Dis., 30(4), 2293-2305, 20230719
  4. Anesthetic management of a patient with Sturge-Weber syndrome in sagittal split ramus osteotomy surgery, CLINICAL CASE REPORTS, 12(4), 202404
  5. Ghost cell odontogenic carcinoma arising in dentinogenic ghost cell tumor, peripheral: A case report, PATHOLOGY INTERNATIONAL, 73(8), 367-372, 202308
  6. Efficacy and safety of remimazolam besilate for sedation in outpatients undergoing impacted third molar extraction: a prospective exploratory study, BMC ORAL HEALTH, 23(1), 20231021
  7. Camouflage Correction of Skeletal Class III Severe Open Bite with Tooth Ankylosis Treated by Temporary Anchorage Devices: A Case Report, DENTISTRY JOURNAL, 11(4), 202304
  8. Analgesia-based Sedation for Oral Surgery in Patients With Chronic Respiratory Obstructive Disease, JOURNAL OF CRANIOFACIAL SURGERY, 34(1), 2023
  9. Chemical inhibition of LSD1 leads to epithelial to mesenchymal transition in vitro of an oral squamous cell carcinoma OM-1 cell line via release from LSD1-dependent suppression of ZEB1, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 647, 23-29, 20230305
  10. Correction of Severe Skeletal Class II High Angle with Mandibular Retrusion and Gummy Smile by Double-Jaw Surgery, BULLETIN OF TOKYO DENTAL COLLEGE, 63(4), 177-187, 2022
  11. Inhibition of angiogenesis and tumor progression of MK-0429, an integrin alpha v beta(3) antagonist, on oral squamous cell carcinoma, JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 148(12), 3281-3292, 202212
  12. Usefulness of Tranexamic Acid Administration During Sagittal Split Ramus Osteotomy, J Craniofac Surg ., 32(1), 273-276, 20210201
  13. In vitro investigation of the cell compatibility and antibacterial properties of titanium treated with calcium and ozone, Dent Mater J ., 40(3), 712-718, 20210529
  14. Long-standing temporomandibular joint dislocation treated by intraoral condylectomy: a case report and review of the literature, JOURNAL OF MEDICAL CASE REPORTS, 16(1), 20220623
  15. Development of a radiomics and machine learning model for predicting occult cervical lymph node metastasis in patients with tongue cancer, ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 134(1), 93-101, 20220701
  16. Dexamethasone resets stable association of nuclear Snail with LSD1 concomitant with transition from EMT to partial EMT, BIOCHEMISTRY AND BIOPHYSICS REPORTS, 30, 20220701
  17. In vitro investigation of the cell compatibility and antibacterial properties of titanium treated with calcium and ozone, DENTAL MATERIALS JOURNAL, 40(3), 712-718, 20210601
  18. Melatonin enhances cisplatin-induced cell death through inhibition of DERL1 in mesenchymal-like CD44(high) OSCC cells, JOURNAL OF ORAL PATHOLOGY & MEDICINE, 51(3), 281-289, 20220301
  19. PGE(2) targets squamous cell carcinoma cell with the activated epidermal growth factor receptor family for survival against 5-fluorouracil through NR4A2 induction, CANCER LETTERS, 307(2), 227-236, 20110828
  20. Myxolipoma in the tongue - A clinical case report and review of the literature, HEAD & NECK ONCOLOGY, 3, 20111220
  21. Histone acetylation and gastrointestinal carcinogenesis., Ann. N. Y. Acad. Sci., 983, 220-231, 20030401
  22. Detection of human papillomavirus-16 and HPV-18 DNA in normal, dysplastic, and malignant oral epithelium., Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 95, 594-600, 20030401
  23. Correlation of CENP-F gene expression with tumor-proliferating activity in human salivary gland tumors., Oral Oncology, 41, 716-722, 20050401
  24. Increased expression of CENP-H gene in human oral squamous cell carcinomas harboring high-proliferative activity., Oncol.Rep., 16, 1071-1075, 20060401
  25. Effect of trichostatin A on cell growth and expression of cell cycle- and apoptosis-related molecules in human gastric and oral carcinoma cell lines, INTERNATIONAL JOURNAL OF CANCER, 88(6), 992-997, 20001215
  26. Up-regulation of stromal cell-derived factor-1 alpha and its receptor CXCR4 expression accompanied with epithelial-mesenchymal transition in human oral squamous cell carcinoma, ONCOLOGY REPORTS, 19(4), 993-998, 200804
  27. Overexpression of the receptor for hyaluronan-mediated motility, correlates with expression of microtubule-associated protein in human oral squamous cell carcinomas, INTERNATIONAL JOURNAL OF ONCOLOGY, 34(6), 1565-1571, 200906
  28. Snail promotes Cyr61 secretion to prime collective cell migration and form invasive tumor nests in squamous cell carcinoma, CANCER LETTERS, 329(2), 243-252, 20130228
  29. Risk of bacterial contamination of bone harvesting devices used for autogenous bone graft in implant surgery, HEAD & FACE MEDICINE, 9, 20130111
  30. Malignant ossifying fibromyxoid tumor of the tongue: case report and review of the literature, HEAD & FACE MEDICINE, 9, 20130624
  31. AKT Primes Snail-Induced EMT Concomitantly With the Collective Migration of Squamous Cell Carcinoma Cells, JOURNAL OF CELLULAR BIOCHEMISTRY, 114(9), 2039-2049, 201309
  32. Autocrine galectin-1 promotes collective cell migration of squamous cell carcinoma cells through up-regulation of distinct integrins, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 441(4), 904-910, 20131129
  33. Aesthetic recovery of alveolar atrophy following autogenous onlay bone grafting using interconnected porous hydroxyapatite ceramics (IP-CHA) and resorbable poly-L-lactic/polyglycolic acid screws: case report, BMC ORAL HEALTH, 14, 20140602
  34. Professional oral health care reduces the duration of hospital stay in patients undergoing orthognathic surgery, BIOMEDICAL REPORTS, 4(1), 55-58, 201601
  35. CD44(high)/ALDH1(high) head and neck squamous cell carcinoma cells exhibit mesenchymal characteristics and GSK3-dependent cancer stem cell properties, JOURNAL OF ORAL PATHOLOGY & MEDICINE, 45(3), 180-188, 201603
  36. Gene expression profiling to identify genes associated with high-invasiveness in human squamous cell carcinoma with epithelial-to-mesenchymal transition, CANCER LETTERS, 264(2), 256-264, 2008
  37. Delta Np63 alpha-dependent expression of Id-3 distinctively suppresses the invasiveness of human squamous cell carcinoma, INTERNATIONAL JOURNAL OF CANCER, 124(12), 2837-2844, 2009
  38. Histopathological evaluation including cytokeratin 13 and Ki-67 in the border between Lugol-stained and -unstained areas, ONCOLOGY REPORTS, 24(1), 9-14, 2010
  39. Increased telomerase activity and hTERT expression in human salivary gland carcinomas, ONCOLOGY LETTERS, 2(5), 845-850, 2011
  40. Snail-induced CD44(high) cells in HNSCC with high ABC transporter capacity exhibit potent resistance to cisplatin and docetaxel, INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 9(8), 7908-7918, 2016
  41. Resection of a tongue fibroma in a patient with serum butyrylcholinesterase deficiency, Journal of Oral Surgery Society of Japan, 52(5), 303-306, 20060520
  42. Comparison of genes expressed in cell lines derived from the primary lesion and lymph node metastasis of a squamous cell carcinoma arising in the tongue : A trial designed to identify metastasis-related genes, Journal of Oral Surgery Society of Japan, 51(10), 482-488, 20051020
  43. A case of congenital tooth with cleft uvula, 15(2), 131-134, 20051225
  44. The analysis of deltaNp63alpha-depending invasive ability in squamous cell carcinoma through epithelial-mesenchymal transition, 26(1), 20070331
  45. Hemostatic Management for Tooth Extraction in Patients Receiving Anticoagulant Therapy, 39(1), 19-23, 20070601
  46. Immediate Reconstructive Surgery with Pedicle and Free Myocutaneous Flap after Oral Cancer Ablation, 38(2), 143-149, 20061201
  47. A Case Report : Superselective Intraarterial Concomitant Chemoradiation for Advanced Tongue Carcinoma by Seldinger Technique, 38(2), 157-161, 20061201
  48. Autologous Blood Injection for the Treatment of Recurrent Temporomandibular Joint Dislocation in a Demented Patient, 38(1), 80-83, 20060601
  49. The Treatment of the Maxillofacial Bone Fractures with the Bioabsorbable Poly-L-Lactide Bone Mini Plate, 37(2), 145-150, 20051201
  50. Comparison of Genes Expressed in Cell Lines Derived from a Primary Lesion and Metastasized Lymph Nodes of Tongue Squamous Cell Carcinoma : A Trial Study of Identifying Metastasis-related Genes, 43, 64-69, 20070301
  51. Increased Expression of CENP-H Gene in Human Salivary Gland Carcinomas, OSI, 5(1), 43-51, 20080501
  52. A case of basal cell adenoma arising in the submandibular gland, 58(2), 92-96, 20120220
  53. A case of peripheral osteoma arising in the inferior border of the mandible, 58(4), 272-276, 20120420
  54. A case of acute sialadenitis in a submandibular gland induced by a penetrated fish bone, 58(6), 400-404, 20120620
  55. Third molar extraction during bypass therapy in a patient with hemophilia A inhibitor, Journal of Oral Surgery Society of Japan, 59(10), 658-662, 2013
  56. A case of a large osteoma containing maxillary mucosa in the maxillary sinus, Japanese Journal of Oral and Maxillofacial Surgery, 61(12), 673-677, 20151201
  57. Preoperative oral health care reduces postoperative inflammation and complications in oral cancer patients., Experimental and therapeutic medicine, 12(3), 2016
  58. Differential regulation by IFN‑ganma on TNF‑alpha‑induced chemokine expression in synovial fibroblasts from temporomandibular joint., Mol Med Rep., 10, 20170907
  59. Clinicopathological analysis of salivary gland carcinomas and literature review, MOLECULAR AND CLINICAL ONCOLOGY, 3(1), 202-206, 2015
  60. A case of severe stomatitis associated with pancytopenia that developed during methotrexate therapy for rheumatoid arthritis, Japanese Journal of Oral and Maxillofacial Surgery, 64(8), 497-501, 20180801
  61. A Case of Mandibular Prognathism with Crouzon Syndrome Treated by Application of Maxillary Distraction Osteogenesis and Sagittal Split Ramus Osteotomy, Jpn. J. Jaw Deform, 28(1), 52-60, 20180401
  62. A research analysis of the Thrombocytopenia patient with Compound odontoma in the maxillary primary canine, Japanese Journal of Dental Welfare, 23(1), 26-25, 20180601
  63. The Cases of Inverted Supernumerary Tooth in the Central Maxilla Which was Removed Surgically from the Floor of the Nasal Cavity, The journal of Hiroshima University Dental Society, 50(1), 21-25, 20180601
  64. A case of skeletalk maxillary protrusion with open bite and hypoplasia of the condyle treated using maxillary surgery alone, The Japanese Journal of Jaw Deformities, 29(1), 59-65, 20190514
  65. A case of venous aneurysm in the submandibular region, Japanese Journal of Oral and Maxillofacial Surgery, 65(10), 689-693, 20191020
  66. Zoledronate Inhibits Osteoclast Differentiation via Suppressing Vascular Endothelial Growth Factor Receptor 2 Expression, BIOCHEMICAL GENETICS, 58(3), 473-489, 20200601
  67. Morphological Evaluation of Bone by CT to Determine Primary Stability-Clinical Study, MATERIALS, 13(11), 202006
  68. A case of Angioleiomyoma of the Hard Palate, The journal of Hiroshima University Dental Society, 51(2), 116-120, 20191201
  69. A case of Lipoma of the Oral Floor Filling the Sublingual Space, The journal of Hiroshima University Dental Society, 51(2), 121-126, 20191201
  70. Melatonin-induced miR-181c-5p enhances osteogenic differentiation and mineralization of human jawbone-derived osteoblastic cells, MOLECULAR MEDICINE REPORTS, 22(4), 3549-3558, 202010
  71. Intranasal midazolam conscious sedation for dental surgery in child with left ventricular noncompaction, JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY, 33(2), 165-168, 20210301
  72. High cervical transmasseteric anteroparotid approach for mandibular condylectomy, JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY, 33(3), 276-280, 20210501
  73. The squamous cell carcinoma cell line OM-1 retains both p75-dependent stratified epithelial progenitor potential and cancer stem cell properties, BIOCHEMISTRY AND BIOPHYSICS REPORTS, 26, 20210701
  74. Relationships between intraoral ultrasonographic and histopathological findings in patients with tongue cancer, HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 43(9), 2778-2785, 20210901
  75. Effects of miR-224-5p-enhanced downregulation of pannexin-1 on docetaxel-induced apoptosis in amoeboid-like CD44(high) oral cancer cells, EUROPEAN JOURNAL OF ORAL SCIENCES, 129(5), 20211001
  76. Postoperative Complications of Impacted Mandibular Third Molar Extraction Related to Patient's Age and Surgical Difficulty Level: A Cross-Sectional Retrospective Study, INTERNATIONAL JOURNAL OF DENTISTRY, 2022, 20220103

Publications such as books

  1. 2019/10/01, Dental Implant Treatment in Medically Compromised Patients, This book is an ideal reference guide for clinicians seeking to improve their decision making and treatment outcomes when placing dental implants in medically compromised patients, in whom conditions for osseointegration and soft tissue healing may be unfavorable. Up-to-date information is provided on the potential impacts of a wide variety of diseases and disorders on dental implant treatment and the factors that need to be considered when deciding on the feasibility of such treatment. More specifically, for each condition possible disease-related changes in the oral environment are explained and key treatment issues are identified, including surgical and prosthodontic aspects and pharmacological considerations. The book will help general dentists, periodontists, and oral surgeons to reduce the risk of treatment failure and complications and to ensure that the implant therapy is successful in achieving excellent quality of life and functional benefits, thereby improving patient satisfaction., Dental Implant Treatment in Medically Compromised Patients, Springer, 2019, 10, Scholarly Book, Joint work, English, Quan Yuan, Masaaki Takechi, Shigehiro Ono et al., 978-3-030-28557-9, 253, 63-64, 4.4.Hepatitis

Invited Lecture, Oral Presentation, Poster Presentation

  1. A case of Central Giant Cell Granuloma of the condyle, Okuda S, Ono S, Tada M, Ishida F, Mizuta K, Uetsuki R, Kakimoto N, Ogawa I, Takechi M, The 38th Annual Meeting of Japanese Society of Oral Oncology, 2020/01/24, Without Invitation, Japanese
  2. Clinical investigation of implant cases with complication in our department after the implant treatment, Ninomiya N, Ono S, Tada M, Nakagawa T, Ishida F, Okuda S, Takechi M, The 23rd Annual Meeting of the Japanese Academy of Maxillofacial implants, 2019/11/30, Without Invitation, Japanese
  3. A case of occlusal reconstruction by Bone Anchored Device for Wide Edentulous Area after partial maxillectomy, Ishioka Y, Ono S, Murodumi H, Yokoyama S, Sasaki K, Ninomiya Y, Kubo T, Takechi M, The 39th Annual Meeting of Japanese Society of Oral Implantology Chugoku Shikoku Branch, 2019/11/17, Without Invitation, Japanese
  4. Analysis of provided treatment-resistant by EMT in oral squamous carcinoma, Higashikawa K, Uetsuki R, Ishida F, Shigeishi H, Shimasue H, Ono S, Takechi M, The 64th Annual Meeting of the Japanese Society of Oral and Maxillofacial Surgery (Sapporo), 2019/10/26, Without Invitation, Japanese, Hokkaido University, Sapporo
  5. 24) Clinical study of failed implant cases in our department, Ninomiya Y, Ono S, Mizuta K, Tada M, Takechi M, The 64th Annual Meeting of the Japanese Society of Oral and Maxillofacial Surgery, 2019/10/25, Without Invitation, Japanese
  6. Analyses of the cancer stem cell-like property in Snail-induced EMT phenotype oral cancer cells, Uetsuki R, Higashikawa K, Shigeishi H, Ishida F, Ono S, Shimasue H, Takechi M, The 64th Annual Meeting of the Japanese Society of Oral and Maxillofacial Surgery, 2019/10/25, Without Invitation, Japanese
  7. A case of adenosquamous carcinoma of the mandibular, Fukui A, Ono S, Ohta K, Tada M, Ogawa I, Takechi M, The 64th Annual Meeting of the Japanese Society of Oral and Maxillofacial Surgery, 2019/10/25, Without Invitation, Japanese
  8. A case of mesenchymal chondrosarcoma of the mandible., Tada M, Ono S, Ohta K, Okuda S, Ogawa I, Sakamoto S, Kakimoto N, Konishi M, Takechi M, The 64th Annual Meeting of the Japanese Society of Oral and Maxillofacial Surgery, 2019/10/25, Without Invitation, Japanese
  9. Three cases of surgical orthodontics treatment for jaw deformities with condyle deformity, Ono S, Mizuta K, Tada M, Sasaki K, Naruse T, Uetsuki R, Takechi M, The 64th Annual Meeting of the Japanese Society of Oral and Maxillofacial Surgery, 2019/10/25, Without Invitation, Japanese, Sapporo
  10. Analysis of Runx2-induced expression of melatonin in human mandible osteoblasts origin, Murodumi H, Shigeishi H, Kato H, Yokoyama S, Sakuma M, Tada M, Ono S, Ohta K, Takechi M, The 67th Japanese Stomatological Society The Chugoku & Shikoku Districts, 2019/10/12, Without Invitation, Japanese, Hiroshima University
  11. 14) The Effect of Tranexamic Acid during Sagittal Split Ramus Osteotomy, Yoshida M, Yoshida K, Ono S, Shimizu Y, Mukai A, Doi M, Irifune M, The 2019 IADR/AADR/CADR General Session & Exhibition, 2019/09/25, Without Invitation, English, IADR, Vancouver, CANADA
  12. A case of intraoral condylectomy for dislocation of temporomandibular joint due to prolonged case of condyler of mandible, Uetsuki R, Ono S, Tada M, Mizuta K, Takechi M, The 21st Annual Meeting of Japanese Society of Oral and Maxillofacial Trauma, 2019/07/05, Without Invitation, Japanese, Gifu University, Gifu
  13. A Case of Horizontal Alveolar Bone Resorption treated by Splitcrest Technique and GBR with Interconnected Porous Hydroxyapatite Ceramics, Sasaki K, Ninomiya Y, Tsuka H, Ishida F, Mizuta K, Ono S, Ohta K, Tsuga K, Takechi M, 103th Hiroshima University Dental Society, 2019/06/15, Without Invitation, Japanese
  14. A case of skeletal maxillary protrusion with open bite and hypoplasia of the condyle treated using maxillary surgery alone, Uetsuki R, Ono S, Kaku M, Yamamoto T, Ohta K, Mizuta K, Tanimoto K, Takechi M, The 52th Annual Meeting of Hiroshima University Dental Society, 2019/06/15, Without Invitation, English, The Hiroshima University Dental Society, Hiroshima
  15. A case of orthognathic surgery for jaw deformity due to condylar fracture in early childhood, Mizuta K, Ono S, Hanaoka K, Hanaoka H, Kaku M, Sasaki K, Murodumi H, Yamamoto T, Tanimoto K, Takechi M, The 29th Annual Meeting of the Japanese Society for Jaw Deformities, 2019/06/08, Without Invitation, Japanese, Nihon University, Tokyo
  16. A case of venous aneurysm in the submandibular region, Uetsuki R, Ono S, Tada M, Inoue S, Ogawa I, Takechi M, The 48th Congress of the Japanese Society of Oral and Maxillofacial Surgeons Chugoku Shikoku Branch, 2019/05/25, Without Invitation, Japanese, Fukuyama
  17. 2) A Case report of Left Cervical Metastasis of Tongue Cancer During Pregnancy, Mizuta K, Ohta K, Ono S, Sasaki K, Kato H, Takechi M, The 37th Annual Meeting of Japanese Society of Oral Oncology, 2019/01/24, Without Invitation, Japanese, Nagasaki University, Nagasaki
  18. Occlusal Reconstruction Using Bone Anchored Device for Wide Edentulous After Surgical Treatments of Carcinoma of the Maxillary, Ono S, Mizuta K, Uetsuki R, Ohta K, Takechi M, The 37th Annual Meeting of Japanese Society of Oral Oncology, 2019/01/24, Without Invitation, Japanese, Nagasaki University, Nagasaki
  19. Two Cases of Occlusal Reconstruction by Bone Anchored Device for Wide Edentulous Area after Partial Maxillectomy, Ono S, Ninomiya Y, Ishida F, Tada M, Ohta K, Okuda S, Takechi M, The 22nd Annual Meeting of Japanese Academy of Maxillofacial Implants, 2018/12/01, Without Invitation, Japanese
  20. A Case using Absorbable Mesh in Bone Window of Maxillary Sinus Elevation, Ninomiya Y, Ono S, Tada M, Ishida F, Ohta K, Okuda S, Takechi M, The 22nd Annual Meeting of Japanese Academy of Maxillofacial Implants, 2018/12/01, Without Invitation, Japanese, Kanagawa Dental college, Tokyo
  21. A Case Report of the Cervical Necrotising Fasciitis with Diabetes, Fukada S, Shimasue H, Ohta K, Ono S, Fukui A, Sasaki K, Ishida Y, Sakuma M, Mizuta K, Takechi M, The 66th Japanese Society of Oral Science, Branch of Chugoku and Shikoku Region, 2018/11/22, Without Invitation, Japanese
  22. A Case of GBR with NEOBONE, Okuda S, Ninomiya Y, IshidaF, Tada M, Ono S, Tsuka H, Tsuga K, Takechi M, The 38th Japanese Society of Oral Implantology, 2018/11/18, Without Invitation, Japanese
  23. Two Case of Bone Anchored Device for Wide Edentulous Area in Patient with Maxillary Pertectomy, Ono S, Takechi M, Sasaki K, Seino S, Uetsuki R, Ninomiya Y, Tohmori H, Ohta K, The 63th Congress of the japanese Society of Oral and Maxillofacial surgeons, 2018/11/03, Without Invitation, Japanese
  24. Clinical Study of Pediatric Patients during the Past 10 Years in Our Department, Sasaki K, Ono S, Yokoyama S, Fukada S, Shigeishi H, Takechi M, The 63th Congress of the japanese Society of Oral and Maxillofacial surgeons, 2018/11/03, Without Invitation, Japanese
  25. Analysis of trans-differenciation properties in a tongue cancer-derived cell line OM-1, Uetsuki R, Higashikawa K, Shigeishi H, Ishida F, Ono S, Shimasue H, Takechi M, The 63th Congress of the japanese Society of Oral and Maxillofacial surgeons, 2018/11/02, Without Invitation, Japanese
  26. A case of severe stomatitis associated with pancytopenia that developed during methotrexate therapy for rheumatoid arthritis, Seino S, Ono S, Murodumi H, Shimasue H, Mizuta Ku, Takechi M, The 102th Annual Meeting of HiroshimaUniversity Dental Society, 2018/09/30, Without Invitation, Japanese, Hiroshima University, Hiroshima
  27. A case of facial-cervical-mediastinal emphysema after CO2 raser treatment for Dental Use, Ishida Y, Ohta K, Sakuma M, Okuda S, Ono S, Takechi M, The 102th Annual Meeting of HiroshimaUniversity Dental Society, 2018/09/25, Without Invitation, Japanese
  28. A case report of reducation of taste disorder by hypozincemia drug Nobelzin®, Murodumi H, Ohtra K, Shintani T, Kato H, Sakuma M, Ono S, Shigeishi H, Kurihara H, Takechi M, The28th Annual Meting of Japanese Society of Oral Science, 2018/09/14, Without Invitation, Japanese
  29. Two case of Implant treatment for Maxillofacial Trauma by Jumping Suicide, Yokoyama S, Mizuta K, Ninomiya Y, Ono S, Tada M, Sasaki K, Takechi M, The48th Annual Meeting of Japanese Society of Oral Implantology, 2018/09/14, Without Invitation, Japanese, Osaka
  30. A Case of Orthognathic Surgery for a patient with facial asymmetry cased by mandible fracture in his childhood, Mizuta K, Ono S, Sasaki K, Murodumi H, Takechi M, The20th Annual Meeting of Japanese Society of Oral and Maxillofacial Traumatorogy, 2018/07/14, Without Invitation, Japanese
  31. A Case of Orthognathic Surgery for an Elderly Mandibular Prognathism Patient with Many Missing Teeth, The28th Annual Meeting of Japanese Society for Jaw Deformities, 2018/06/14, Without Invitation, Japanese
  32. A case of orthognathic surgical correction of mandibular prognathism with congenital myotonic dystrophy, Fukui A, Ono S, Ohta K, Kunimatsu R, Sumi K, Oki K, Tanimoto K, Takechi M, The28th Annual Meeting of Japanese Society for Jaw Deformities, 2018/06/14, Without Invitation, Japanese
  33. Clinical Analysis of Maxillifacial Trauma Patients in Our Department, Sasaki K, Mizuta K, Murodumi H, Ono S, Takechi M, The 72th Annual Meeting of Japanese Stmatological Society, 2018/05/12, Without Invitation, Japanese
  34. Evaluation of epithelial stem cell-like properties of oral squamous cll carcinoma cells, Uetsuki R, Ono S, Ohta K, Takechi M, The 36th Annual Meeting of Japanese Society of Oral Oncology, 2018/01/25, Without Invitation, Japanese, Niigata University, Niigata
  35. The Clinical Statistical Analysis of Elderly Oral Cancer Patients during 10 Years in Our Department, Ono, Uetsuki R, Ohta K, Takechi M, The 36th Annual Meeting of Japanese Society of Oral Oncology, 2018/01/25, Without Invitation, Japanese, Niigata University, Niigata
  36. The Clinical statistical Analysis of Elderly Oral Cancer patients in our Department, Ono S, 62th JOMS, 2017/10/20, Without Invitation, Japanese, Kyoto
  37. Histological examination of maxillary sinus floor elevation using interconnected porous calcium hydroxyapatite, Ninomiya Y, Ono S, Tada M, Nakagawa T, Takechi, M, 19th Annual meeting of the japanease academy of maxillofacial implants and annual meeting of pan pacific implant society, 2015/11/29, Without Invitation, Japanese, Kanagawa Dental college, Yokosuka
  38. Clinical study of the bone augmentation using the interconnected porous calcium hydroxyapatite, Tada M, Ninomiya Y, Ohta K, Nakagawa T, Ono S, Takechi M, 19th Annual meeting of the japanease academy of maxillofacial implants and annual meeting of pan pacific implant society, 2015/11/28, Without Invitation, Japanese, Kanagawa Dental College, Yokosuka
  39. A severe gammy smile patient treated by SSRO and horseshoe osteotomy after distraction osteogenesis, Ono S, Nakagawa T, Kubozono K, Kaku M, Sumi H, Ohta K, Tanimoto K, Takechi M, 98th Hiroshima university dental society, 2015/11/09, Without Invitation, Japanese, hiroshima university, hiroshima
  40. The Evaluation of the stability after Sagittal Split Ramus Osteotomy using Bi-cortical Screw and Locking plate, S. Ono, T. Nakagawa, K. Ohta, H. Shigeishi, K. Higashikawa, M. Takechi, The 60th congress of Japanese Society of Oral and Maxillofacial Surgeons, 2015/10/16, Without Invitation, Japanese, Gifu University, Nagoya
  41. Zinc transporter switch in the EMT induction mechanism of oral cancer cell, Uetsuki R, Higashikawa K, Okui G, Tanaka F, Yamamoto K, Shigeishi H, Ono S, Takechi M, The 60th congress of the japanese society of oral and maxillofacial surgeons, 2015/10/16, Without Invitation, Japanese, Gifu university, Nagoya
  42. A clinical study of maxillary sinus floor elevation using interconnected calcium hydroxyapatite, Ninomiya Y, Takechi M, Ohta K, Ono S, Nakagawa T, The 45th Annual meeting of tne japanese society of oral inplantology, 2015/09/23, Without Invitation, Japanese, Okayama university, Okayama
  43. Clinical study of the bone augmentation using the interconnected porous calcium hydroxyptite for dental implant treatment, Nakagawa T, Ohta K, Ninomiya Y, Ono S, Takechi M, The 45th Annual meeting of tne japanese society of oral inplantology, 2015/09/23, Without Invitation, Japanese, Okayama university, Okayama
  44. A Case of Orthognathic Surgical Correction of Mandibular Prognathism with L oss of Molar Occlusion, S.Ono, T. Nakagawa, J. Ohtani, E. Ishikawa, N, Oki, K, Tanimoto, M. Takechi, The 25th Annual Meeting of The Japanese Society for Jaw Defomites, 2015/06/04, Without Invitation, Japanese, Tokyo Dental College, Tokyo
  45. A mandibular prognathism with open bite case re-treated with glossectomy after orthognathic treatment, Date T, Ko M, Nakao H, Hirose N, Ueda H, Ono S, Tanimoto K, 25th japanese society of jaw deformity, 2015/06/04, Without Invitation, Japanese
  46. Anatomical Analysis, Yokoyama S, Ninomiya Y, Murodumi H, Ono S, Tada M, Ohta K, Takechi M, 2015/05/12, Without Invitation, Japanese, Aichi Gakuin University, Nagoya
  47. A Clinical Study of Factors Affecting the Implant Stability Quotient, Shigehiro Ono, Yoshiaki Ninomiya, Kouji Ohta, Takayuki Nakagawa, Megumi Takamoto, Masaaki Takechi, JAMI, 2014/11/29, Without Invitation, Japanese, Shimane University, Izumo
  48. A Clinical Study of the Implant Stability Quotient and the Insertion Torque at Implant Placement, Shigehiro Ono, AAOMS 96th Annual Meeting, 2014/09/11, Without Invitation, English, AAOMS, Honolulu
  49. Prognostic utility of standardized uptake value using pre-treatment PET/CT in oral cancer patients., Mizuta K, Ohta K, Ono S, Nakagawa T, Fujimoto S, Okumura T, Uetsuki R, Takechi M, 2014/06/21, Without Invitation, Japanese
  50. Application of maxilla/alveolar distraction osteogenesis and two-jaw surgery to a patient with Crouzon syndrome, 2014/06/10, Without Invitation, Japanese
  51. A severe gammy smile patient with opisthogenia treated by SSRO and horseshoe osteotomy after distraction osteogenesis of mandible: a case report, Without Invitation, Japanese
  52. A case of facial-cervical-mediastinal emphysema after CO2 raser treatment, Ishida Y, Ohta K, Sakuma M, Okuda S, Ono S, Takechi M, The 47th Congress of Japanese Oral and Maxillofacial Surgeons, Chu-Shikoku Branch, Without Invitation, Japanese
  53. A case of Sagittal Split Ramus Osteotomy for Mandibular Prognathism with Congenital Myotonic dystrophy, Fukui A, Ono S, Ohta K, Takechi M, The 63th Congress of the japanese Society of Oral and Maxillofacial surgeons, Without Invitation, Japanese
  54. A Case of tooth Loss following Trigeminal Herpes Zoster Infection, Kubozono K, OkumuraT, Ono S, Takechi M, Tanaka K, The 63th Congress of the japanese Society of Oral and Maxillofacial surgeons, Without Invitation, Japanese
  55. A Case of Sinus Floor Elevation for a Patient with HIV Infection, Ishida, F, Ono S, Tada M, Ninomiya Y, Takechi M, The 22nd Annual Meeting of Japanese Academy of Maxillofacial Implants, Without Invitation, Japanese

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI, 2014, 2016
  2. KAKENHI, Expression and functional analysis of RHAMM in human salivary gland carcinomas, 2011, 2013
  3. KAKENHI, 2010, 2014
  4. KAKENHI, The participation of micro RNA acquiring the ability with high-invasiveness via Epithelial-mesenchymal Transition in squamous cell carcinoma, 2009, 2010
  5. KAKENHI, Analysis of epithelial integrity system in tumor invasion and metastasis of oral cancer, 2009, 2011
  6. KAKENHI, VEGF-C is required for the infiltration of squamous cell carcinomavia epithelial-mesenchymal transition, 2007, 2008
  7. KAKENHI, Functional Analysis of EMT and p63 in the invasiveness and metastasis of Oral cancer, 2007, 2008
  8. KAKENHI, Control of invasion and metastasis of oral cancer via clarification of the epithelial-mesenchymal transition, 2006, 2009
  9. KAKENHI, Snail-induced downregulation of deltaNp63 acquires invasive phenotype of human squamous cell carcinoma, 2005, 2007
  10. KAKENHI, 2005, 2006
  11. KAKENHI, Analysis of Molecular Mechanisms of Invasion and Metastasis of Oral Cancer via Epithelial-Mesenchymal Transition, 2003, 2005
  12. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2017, 2019
  13. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2020, 2022

Social Activities

History as Committee Members

  1. representative of the Japanese Society of Oral and Maxillofacial Surgeons, 2020/04/01