HIDEO SIGEMATSU

Last Updated :2024/02/01

Affiliations, Positions
Research Institute for Radiation Biology and Medicine, Associate Professor or Lecturer
E-mail
shigematu1330hiroshima-u.ac.jp
Self-introduction
I work as a breast oncologist. My research theme is omisson of surgery for breast cancer patients showing clinical complete response to primary systemic therapy.

Basic Information

Academic Degrees

  • Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;General surgery

Educational Activity

Course in Charge

  1. 2023, Graduate Education (Doctoral Program) , 1Term, Practice of Oncology

Research Activities

Academic Papers

  1. Long-Term Outcomes of a Randomized Study of Neoadjuvant Induction Dual HER2 Blockade with Trastuzumab and Lapatinib Followed by Weekly Paclitaxel Plus Dual HER2 Blockade for HER2-Positive Primary Breast Cancer (Neo-Lath Study)., Cancers, 20210809
  2. Omitting surgery for early breast cancer showing clinical complete response to primary systemic therapy, Jpn J Clin Oncol, 20200610
  3. Cryotherapy for the prevention of weekly paclitaxel-induced peripheral adverse events in breast cancer patients, Support Care Cancer, 20201028
  4. Minimal prognostic significance of sentinel lymph node metastasis in patients with cT1-2 and cN0 breast cancer, World J Surg Oncol, 20190223
  5. Effect of denosumab on low bone mineral density in postmenopausal Japanese women receiving adjuvant aromatase inhibitors for non-metastatic breast cancer: 24-month results, Breast Cancer, 20180727
  6. Overexpression of topoisomerase II alpha protein is a factor for poor prognosis in patients with luminal B breast cancer, Oncotarget, 20180101
  7. Comparison of CK-IHC assay on serial frozen sections, the OSNA assay, and in combination for intraoperative evaluation of SLN metastases in breast cancer., Breast Cancer, 20171101
  8. Role of 18F-PET/CT in Predicting Prognosis of Patients With Breast Cancer After Neoadjuvant Chemotherapy., Clin Breast Cancer, 20170919
  9. A case report of locally advanced triple negative breast cancer showing pathological complete response to weekly paclitaxel with bevacizumab treatment following disease progression during anthracycline-based neoadjuvant chemotherapy., Int J Surg Case Rep, 293-296, 20170901
  10. Neutrophil elastase induces cell proliferation and migration by the release of TGF-alpha, PDGF and VEGF in esophageal cell lines, Oncol Rep, 17(1), 161-7, 20070101
  11. Significant survival improvement of patients with recurrent breast cancer in the periods 2001-2008 vs. 1992-2000, BMC CANCER, 11, 20110331
  12. A case of HER-2-positive recurrent breast cancer showing a clinically complete response to trastuzumab-containing chemotherapy after primary treatment of triple-negative breast cancer, WORLD JOURNAL OF SURGICAL ONCOLOGY, 9, 20111107
  13. Technical Feasibility and Cosmetic Advantage of Hybrid Endoscopy-Assisted Breast-Conserving Surgery for Breast Cancer Patients, JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES, 23(2), 91-99, 201302
  14. Role of FDG-PET/CT in evaluating surgical outcomes of operable breast cancer - Usefulness for malignant grade of triple-negative breast cancer, BREAST, 22(5), 958-963, 201310
  15. Three models for predicting the risk of non-sentinel lymph node metastasis in Japanese breast cancer patients, BREAST CANCER, 21(5), 571-575, 201409
  16. Role of FDG-PET/CT in Prediction of Underestimation of Invasive Breast Cancer in Cases of Ductal Carcinoma In Situ Diagnosed at Needle Biopsy, CLINICAL BREAST CANCER, 14(5), 358-364, 201410
  17. Utility of F-18 FDG-PET/CT for predicting prognosis of luminal-type breast cancer, BREAST CANCER RESEARCH AND TREATMENT, 150(1), 209-217, 201502
  18. The Efficacy and Safety of Preoperative Chemotherapy With Triweekly Abraxane and Cyclophosphamide Followed by 5-Fluorouracil, Epirubicin, and Cyclophosphamide Therapy for Resectable Breast Cancer: A Multicenter Clinical Trial, CLINICAL BREAST CANCER, 15(2), 110-116, 201504
  19. Clinical Significance of Extracapsular Invasion at Sentinel Lymph Nodes in Breast Cancer Patients with Sentinel Lymph Node Involvement, ANNALS OF SURGICAL ONCOLOGY, 22(7), 2365-2371, 201507
  20. EVALUATION OF MALIGNANCY GRADE OF BREAST CANCER USING PERFLUBUTANE-ENHANCED ULTRASONOGRAPHY, ULTRASOUND IN MEDICINE AND BIOLOGY, 42(5), 1049-1057, 201605
  21. Ability of contrast-enhanced ultrasonography to determine clinical responses of breast cancer to neoadjuvant chemotherapy, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 46(4), 303-309, 201604